fluoxetine and maprotiline

fluoxetine has been researched along with maprotiline in 71 studies

Research

Studies (71)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (16.90)	18.7374
1990's	18 (25.35)	18.2507
2000's	24 (33.80)	29.6817
2010's	17 (23.94)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Ahman, M; Holmén, AG; Wan, H	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Muscat, R; Papp, M; Willner, P	1
Maj, J; Rogóz, Z; Skuza, G; Sowińska, H	2
Cohen, LJ; Grothe, DR	1
Tejani-Butt, SM	1
Bianchi, E; Brunello, N; Perez, J; Racagni, G; Tinelli, D	1
de Jonghe, F; Ravelli, DP; Tuynman-Qua, H	1
Asakura, M; Imafuku, J; Kubota, H; Nakanishi, J; Nishizaki, J; Osada, K; Sato, A; Shibata, M; Shimbo, K; Tsukamoto, T	1
Haber, H; Poelinger, W	1
Schaffler, K	1
Asakura, M; Hasegawa, K; Imafuku, J; Ino, M; Kubota, H; Nishizaki, J; Sato, A; Shinbo, K; Tsukamoto, T	1
Ostrow, D	1
Hrdina, PD	1
Brown, TM; Evans, DL; Golden, RN; Miller, H	1
Abrahamsson, T; Carlsson, L	1
Marsden, CA; Routledge, C	1
Hauser, K; Häusler, A; Meeker, JB	1
Klimek, V; Kordecka-Magiera, A; Maj, J; Mogilnicka, E	1
Janne, P; Lejeune, D; Reynaert, C; Vause, M; Zdanowicz, N	1
Baker, GB; McManus, DJ; Todd, KG	1
Blier, P; De Montigny, C; Mongeau, R	1
Haenel, T; Stöckli, HR; Truog, P	1
Klimek, V; Mackowiak, M; Zak-Knapik, J	1
Battistin, L; Casson, S; Dam, M; De Boni, A; Ermani, M; Freo, U; Piron, L; Pizzolato, G; Tonin, P	1
Boyeson, MG	1
Hwang, CC; Ko, HC; Lu, RB; Shiah, IS	1
Bourin, M; Redrobe, JP	1
Lopukhov, IG	1
Aymard, G; Diquet, B; Livi, P; Pham, YT	1
Inoue, K; Sugimoto, Y; Yamada, J	1
Amelin, AV; Gonchar, MA; Korenko, LA; Skoromets, AA; Tumelevich, BCh	1
Capa Kaya, G; Degirmenci, B; Derebek, E; Durak, H; Ozdogan, O; Sayit, E; Turhal, U; Yemez, B	1
Dossenbach, M; Martényi, F; Metcalfe, S; Mraz, K	1
Hashimoto, S; Hattori, T; Kawasaki, K; Kitamura, Y; Miki, N; Mochizuki, D; Otsuka, Y; Tsujita, R; Yamada, S	1
Ginovart, N; Houle, S; Hussey, D; Meyer, JH; Wilson, AA	1
Sugimoto, Y; Yamada, J	1
Conca, A; Hubmann, MR; König, P; Moll, W; Waschgler, R	1
Amelin, AV; Ignatov, IuD; Skoromets, AA	1
Avedisova, AS; Bochkarev, VK; Liupaeva, NV	1
Ding, YS; Lin, KS	1
Benveniste, H; Carter, P; Ding, YS; Lin, KS; Logan, J	1
Arenas, MC; Everss, E; Ferrer-Añó, A; Martos, AJ; Monleón, S; Parra, A; Vinader-Caerols, C	1
Brenneman, D; Crooke, J; Malatynska, E; Pinhasov, A; Rosenthal, D	1
Chen, YC; Chou, CH; Hung, YJ; Perng, CH; Shen, YC; Yeh, CB	1
Dronjak, S; Gavrilovic, L; Spasojevic, N; Varagic, V	1
Acevedo, EO; Huang, CJ; Sufka, KJ; Warnick, JE	1
Belzung, C; Surget, A; Yalcin, I	1
Farooqui, AA; Lee, LH; Ong, WY; Shui, G; Tan, CH; Wenk, MR	1
Cloonan, SM; Drozgowska, A; Fayne, D; Williams, DC	1
Cloonan, SM; Williams, DC	1
Dronjak, S; Gavrilovic, L; Spasojevic, N	1
Andjelkovic, M; Jankovic, SM; Jovanovic, DB; Zdravkovic, N	1
Cavender, HM; Cooke, JD; Grover, LM; Lima, HK	1

Reviews

4 review(s) available for fluoxetine and maprotiline

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Major depression: its recognition and treatment. Part 2. Second-generation and newer antidepressants. American pharmacy, 1992, Volume: NS32, Issue:11 Topics: Antidepressive Agents; Bupropion; Clomipramine; Depression; Female; Fluoxetine; Humans; Male; Maprotiline; Selective Serotonin Reuptake Inhibitors; Trazodone	1992
The new antidepressants. North Carolina medical journal, 1988, Volume: 49, Issue:10 Topics: Alprazolam; Amoxapine; Antidepressive Agents; Fluoxetine; Maprotiline; Nomifensine; Seizures; Trazodone	1988
[Current views on migraine and anti-migraine preparations]. Vestnik Rossiiskoi akademii meditsinskikh nauk, 2003, Issue:10 Topics: Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Antidepressive Agents; Aza Compounds; Brain; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials as Topic; Clonidine; Fluoxetine; Humans; Imidazoles; Maprotiline; Methysergide; Migraine Disorders; Mutation; Pizotyline; Placebos; Propranolol; Research; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sympatholytics; Vasoconstrictor Agents	2003

Trials

10 trial(s) available for fluoxetine and maprotiline

Article	Year
A randomized, double-blind study of fluoxetine and maprotiline in the treatment of major depression. Pharmacopsychiatry, 1991, Volume: 24, Issue:2 Topics: Adolescent; Adult; Aged; Body Weight; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Hemodynamics; Humans; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales	1991
Fluoxetine 40 mg vs maprotiline 75 mg in the treatment of out-patients with depressive disorders. International clinical psychopharmacology, 1989, Volume: 4 Suppl 1 Topics: Adult; Aged; Anthracenes; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales	1989
The new generation antidepressants: promising innovations or disappointments? The Journal of clinical psychiatry, 1985, Volume: 46, Issue:10 Pt 2 Topics: Alprazolam; Antidepressive Agents; Benzodiazepines; Bupropion; Citalopram; Clinical Trials as Topic; Depressive Disorder; Dopamine; Drug Evaluation; Fluoxetine; Humans; Maprotiline; Nomifensine; Norepinephrine; Propiophenones; Propylamines; Receptors, Neurotransmitter; Serotonin; Trazodone; Zimeldine	1985
Clinical trials of antidepressants: the hidden face: where locus of control appears to play a key role in depression outcome. Psychopharmacology, 1995, Volume: 119, Issue:4 Topics: Adult; Antidepressive Agents; Depression; Fluoxetine; Humans; Internal-External Control; Maprotiline; Paroxetine; Psychiatric Status Rating Scales; Time Factors; Treatment Outcome	1995
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy. Stroke, 1996, Volume: 27, Issue:7 Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Generation; Brain Ischemia; Cerebrovascular Disorders; Depression; Female; Fluoxetine; Hemiplegia; Humans; Male; Maprotiline; Neurologic Examination; Physical Therapy Modalities; Placebos; Psychomotor Performance; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Walking	1996
Plasma free 3-methoxy-4-hydroxyphenylglycol predicts response to fluoxetine. Biological psychiatry, 1997, Apr-01, Volume: 41, Issue:7 Topics: Adult; Antidepressive Agents, Second-Generation; Blood Platelets; Depressive Disorder; Female; Fluoxetine; Humans; Male; Maprotiline; Methoxyhydroxyphenylglycol; Middle Aged; Personality Inventory; Prognosis; Serotonin; Treatment Outcome	1997
[A comparative efficiency of amitriptyline, fluoxetine and maprotiline in prevention of migraine in attack-free period]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2000, Volume: 100, Issue:8 Topics: Acute Disease; Adrenergic Uptake Inhibitors; Adult; Amitriptyline; Analgesics, Non-Narcotic; Female; Fluoxetine; Humans; Male; Maprotiline; Middle Aged; Migraine Disorders; Selective Serotonin Reuptake Inhibitors; Treatment Outcome	2000
Gender differences in the efficacy of fluoxetine and maprotiline in depressed patients: a double-blind trial of antidepressants with serotonergic or norepinephrinergic reuptake inhibition profile. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2001, Volume: 11, Issue:3 Topics: Adrenergic Uptake Inhibitors; Adult; Age Factors; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Sex Factors	2001
Comparisons of glucose-insulin homeostasis following maprotiline and fluoxetine treatment in depressed males. Journal of affective disorders, 2007, Volume: 103, Issue:1-3 Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents, Second-Generation; Blood Glucose; Body Mass Index; Body Weight; Depressive Disorder, Major; Fluoxetine; Glucose Tolerance Test; Homeostasis; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Maprotiline; Personality Inventory; Selective Serotonin Reuptake Inhibitors	2007
Gallbladder emptying in patients with major depression: a case series. Pharmacopsychiatry, 2011, Volume: 44, Issue:5 Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Case-Control Studies; Depressive Disorder, Major; Female; Fluoxetine; Gallbladder; Gallbladder Emptying; Humans; Male; Maprotiline; Middle Aged; Organ Size; Ultrasonography	2011

Other Studies

57 other study(ies) available for fluoxetine and maprotiline

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations	2002
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1 Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics	2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Reversal of stress-induced anhedonia by the atypical antidepressants, fluoxetine and maprotiline. Psychopharmacology, 1992, Volume: 109, Issue:4 Topics: Animals; Antidepressive Agents, Second-Generation; Chlordiazepoxide; Conditioning, Operant; Dopamine; Eating; Feeding Behavior; Fluoxetine; Food; Male; Maprotiline; Rats; Reward; Stress, Psychological; Sucrose	1992
The effect of antidepressant drugs on the locomotor hyperactivity induced by MK-801, a non-competitive NMDA receptor antagonist. Neuropharmacology, 1992, Volume: 31, Issue:7 Topics: Animals; Antidepressive Agents; Benzazepines; Citalopram; Dizocilpine Maleate; Fluoxetine; Imipramine; Isomerism; Male; Maprotiline; Motor Activity; Prazosin; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Sulpiride	1992
[3H]nisoxetine: a radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1 Topics: 5,7-Dihydroxytryptamine; Animals; Autoradiography; Binding, Competitive; Brain; Cerebral Cortex; Fluoxetine; Kinetics; Male; Maprotiline; Norepinephrine; Oxidopamine; Radioligand Assay; Rats; Rats, Inbred Strains; Stereoisomerism; Tritium	1992
cAMP binding proteins in the rat cerebral cortex after administration of selective 5-HT and NE reuptake blockers with antidepressant activity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1991, Volume: 4, Issue:1 Topics: Affinity Labels; Animals; Azides; Cerebral Cortex; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Fluoxetine; Male; Maprotiline; Microtubules; Molecular Weight; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Cyclic AMP; Serotonin Antagonists; Stereoisomerism	1991
Involvement of protein kinase in the regulation of beta-adrenergic receptors by antidepressants. International journal of clinical pharmacology research, 1989, Volume: 9, Issue:2 Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Antidepressive Agents; Bucladesine; Cerebral Cortex; Desipramine; Fluoxetine; Injections, Intraventricular; Male; Maprotiline; Mianserin; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Time Factors	1989
Study on performance and alcohol interaction with the antidepressant fluoxetine. International clinical psychopharmacology, 1989, Volume: 4 Suppl 1 Topics: Choice Behavior; Drug Interactions; Electrooculography; Ethanol; Fluoxetine; Humans; Male; Maprotiline; Psychomotor Performance; Reaction Time	1989
Role of serotonin in the regulation of beta-adrenoceptors by antidepressants. European journal of pharmacology, 1987, Sep-02, Volume: 141, Issue:1 Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Cerebral Cortex; Desipramine; Fenclonine; Fluoxetine; In Vitro Techniques; Male; Maprotiline; Membranes; Mianserin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Serotonin	1987
Regulation of high- and low-affinity [3H]imipramine recognition sites in rat brain by chronic treatment with antidepressants. European journal of pharmacology, 1987, Jun-19, Volume: 138, Issue:2 Topics: Animals; Antidepressive Agents; Binding, Competitive; Biogenic Amines; Brain; Carrier Proteins; Fluoxetine; In Vitro Techniques; Iprindole; Kinetics; Male; Maprotiline; Nortriptyline; Phenelzine; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, Neurotransmitter; Serotonin; Synaptosomes	1987
Characterization of the inhibitory effect of some antidepressant drugs on the outward transport of norepinephrine in the ischemic myocardium. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:2 Topics: Animals; Antidepressive Agents; Biological Transport, Active; Chromatography, High Pressure Liquid; Clonidine; Coronary Disease; Desipramine; Fluoxetine; Heart; Isomerism; Lidocaine; Male; Maprotiline; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains	1988
Lack of selectivity between the uptake of [3H]adrenaline and [3H]noradrenaline into rat hypothalamic slices. Journal of neurochemistry, 1987, Volume: 49, Issue:3 Topics: Animals; Benztropine; Desipramine; Epinephrine; Fluoxetine; Hypothalamus; Male; Maprotiline; Norepinephrine; Rats; Rats, Inbred Strains; Tissue Distribution	1987
Effects of subchronic administration of psychoactive substances on the circadian rhythm of urinary corticosterone excretion in rats. Psychoneuroendocrinology, 1985, Volume: 10, Issue:4 Topics: Animals; Antidepressive Agents; Circadian Rhythm; Clorgyline; Corticosterone; Fluoxetine; Imipramine; Male; Maprotiline; Pargyline; Propylamines; Rats; Trimipramine	1985
Chronic treatment with antidepressants: protentiation of clonidine-induced aggression in mice via noradrenergic mechanism. Journal of neural transmission, 1981, Volume: 52, Issue:3 Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents; Brompheniramine; Clonidine; Drug Synergism; Fluoxetine; Humans; Male; Maprotiline; Mice; Zimeldine	1981
The effect of selective inhibitors of noradrenaline and serotonin uptake on reserpine- and apomorphine induced hypothermia in mice. Polish journal of pharmacology and pharmacy, 1983, Volume: 35, Issue:1 Topics: Animals; Apomorphine; Body Temperature; Citalopram; Desipramine; Fluoxetine; Male; Maprotiline; Mice; Norepinephrine; Propylamines; Reserpine; Serotonin Antagonists	1983
Chronic administration of the antidepressants phenelzine, desipramine, clomipramine, or maprotiline decreases binding to 5-hydroxytryptamine2A receptors without affecting benzodiazepine binding sites in rat brain. Cellular and molecular neurobiology, 1995, Volume: 15, Issue:3 Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Brain; Clomipramine; Desipramine; Flunitrazepam; Fluoxetine; Ketanserin; Male; Maprotiline; Phenelzine; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, GABA-A; Receptors, Serotonin; Serotonin Antagonists	1995
Effect of long-term administration of antidepressant drugs on the 5-HT3 receptors that enhance the electrically evoked release of [3H]noradrenaline in the rat hippocampus. European journal of pharmacology, 1994, Dec-12, Volume: 271, Issue:1 Topics: Animals; Antidepressive Agents; Benzamides; Desipramine; Electric Stimulation; Fluoxetine; Hippocampus; In Vitro Techniques; Male; Maprotiline; Moclobemide; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Trimipramine	1994
[A case of rare side effects of certain antidepressive drugs]. Der Nervenarzt, 1995, Volume: 66, Issue:1 Topics: Adult; Antidepressive Agents; Clomipramine; Depressive Disorder; Diagnosis, Differential; Drug Therapy, Combination; Fluoxetine; Humans; Male; Malignant Hyperthermia; Maprotiline; Parkinson Disease, Secondary; Substance-Related Disorders; Tremor	1995
Effects of repeated treatment with fluoxetine and citalopram, 5-HT uptake inhibitors, on 5-HT1A and 5-HT2 receptors in the rat brain. Journal of psychiatry & neuroscience : JPN, 1994, Volume: 19, Issue:1 Topics: Animals; Antidepressive Agents; Binding Sites; Brain; Citalopram; Fluoxetine; Ketanserin; Male; Maprotiline; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin	1994
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy. Stroke, 1996, Volume: 27, Issue:11 Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents, Second-Generation; Cerebrovascular Disorders; Cluster Analysis; Depression; Fluoxetine; Humans; Maprotiline; Psychomotor Performance; Research Design; Selective Serotonin Reuptake Inhibitors	1996
Partial role of 5-HT2 and 5-HT3 receptors in the activity of antidepressants in the mouse forced swimming test. European journal of pharmacology, 1997, May-01, Volume: 325, Issue:2-3 Topics: Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Desipramine; Drug Interactions; Fluoxetine; Fluvoxamine; Imipramine; Ketanserin; Male; Maprotiline; Mice; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming	1997
[A comparative clinical evaluation of the antidepressive activity of fluoxetine and fluvoxamine]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1997, Volume: 97, Issue:4 Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Evaluation; Female; Fluoxetine; Fluvoxamine; Humans; Male; Maprotiline; Middle Aged; Time Factors	1997
Sensitive and rapid method for the simultaneous quantification of five antidepressants with their respective metabolites in plasma using high-performance liquid chromatography with diode-array detection. Journal of chromatography. B, Biomedical sciences and applications, 1997, Oct-24, Volume: 700, Issue:1-2 Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Fluoxetine; Humans; Imipramine; Maprotiline; Sensitivity and Specificity; Spectrophotometry, Ultraviolet	1997
Selective serotonin reuptake inhibitors fluoxetine and fluvoxamine induce hyperglycemia by different mechanisms. European journal of pharmacology, 1999, Oct-15, Volume: 382, Issue:3 Topics: Animals; Blood Glucose; Enzyme Inhibitors; Fenclonine; Fluoxetine; Fluvoxamine; Hyperglycemia; Insulin; Male; Maprotiline; Mice; Selective Serotonin Reuptake Inhibitors; Time Factors	1999
Technetium-99m DTPA inhalation scintigraphy in patients treated with fluoxetine and maprotiline: preliminary results. European journal of nuclear medicine, 2000, Volume: 27, Issue:9 Topics: Administration, Inhalation; Adrenergic Uptake Inhibitors; Adult; Female; Fluoxetine; Humans; Lung; Male; Maprotiline; Metabolic Clearance Rate; Middle Aged; Permeability; Selective Serotonin Reuptake Inhibitors; Serotonin; Smoking; Technetium Tc 99m Pentetate	2000
Neurochemical and behavioural characterization of milnacipran, a serotonin and noradrenaline reuptake inhibitor in rats. Psychopharmacology, 2002, Volume: 162, Issue:3 Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Behavior, Animal; Binding, Competitive; Brain Chemistry; Conditioning, Psychological; Cyclopropanes; Dose-Response Relationship, Drug; Fear; Fluoxetine; Fluvoxamine; Imipramine; Male; Maprotiline; Microdialysis; Milnacipran; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Prefrontal Cortex; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Cell Surface; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Swimming; Synaptosomes; Time Factors	2002
[11C]-DASB, a tool for in vivo measurement of SSRI-induced occupancy of the serotonin transporter: PET characterization and evaluation in cats. Synapse (New York, N.Y.), 2003, Volume: 47, Issue:2 Topics: Adrenergic Uptake Inhibitors; Animals; Benzylamines; Brain; Carrier Proteins; Cats; Citalopram; Dopamine Antagonists; Fluoxetine; Haloperidol; Maprotiline; Membrane Glycoproteins; Membrane Transport Proteins; Monoamine Oxidase Inhibitors; Nerve Tissue Proteins; Piperazines; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Time Factors; Tissue Distribution; Tomography, Emission-Computed; Tranylcypromine	2003
Differential effects of the 5-HT2 receptor antagonist on the anti-immobility effects of noradrenaline and serotonin reuptake inhibitors in the forced swimming test. Brain research, 2002, Dec-20, Volume: 958, Issue:1 Topics: Adrenergic Uptake Inhibitors; Animals; Brain; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Drug Interactions; Ergolines; Fluoxetine; Fluvoxamine; Male; Maprotiline; Mice; Motor Activity; Neurons; Norepinephrine; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Synaptic Transmission	2002
Simultaneous quantification of citalopram, clozapine, fluoxetine, norfluoxetine, maprotiline, desmethylmaprotiline and trazodone in human serum by HPLC analysis. International journal of clinical pharmacology and therapeutics, 2002, Volume: 40, Issue:12 Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Chromatography, High Pressure Liquid; Citalopram; Clozapine; Fluoxetine; Humans; Maprotiline; Trazodone	2002
[Placebo to antidepressant effects ratio by electroencephalographic data]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2004, Volume: 104, Issue:11 Topics: Adult; Alpha Rhythm; Antidepressive Agents, Second-Generation; Depression; Electroencephalography; Female; Fluoxetine; Functional Laterality; Humans; Male; Maprotiline; Middle Aged; Placebo Effect; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index	2004
Synthesis and C-11 labeling of three potent norepinephrine transporter selective ligands ((R)-nisoxetine, lortalamine, and oxaprotiline) for comparative PET studies in baboons. Bioorganic & medicinal chemistry, 2005, Aug-01, Volume: 13, Issue:15 Topics: Animals; Benzopyrans; Carbon Radioisotopes; Fluoxetine; Ligands; Maprotiline; Molecular Structure; Norepinephrine Plasma Membrane Transport Proteins; Papio; Positron-Emission Tomography; Stereoisomerism; Symporters	2005
Comparative evaluation of positron emission tomography radiotracers for imaging the norepinephrine transporter: (S,S) and (R,R) enantiomers of reboxetine analogs ([11C]methylreboxetine, 3-Cl-[11C]methylreboxetine and [18F]fluororeboxetine), (R)-[11C]nisox Journal of neurochemistry, 2005, Volume: 94, Issue:2 Topics: Adrenergic Uptake Inhibitors; Animals; Autoradiography; Benzopyrans; Binding, Competitive; Brain; Brain Chemistry; Brain Mapping; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Evaluation Studies as Topic; Fluorine Radioisotopes; Fluoxetine; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Maprotiline; Mice; Morpholines; Nordefrin; Norepinephrine Plasma Membrane Transport Proteins; Papio; Positron-Emission Tomography; Protein Binding; Radioligand Assay; Reboxetine; Symporters; Time Factors; Tissue Distribution	2005
Are the effects of the antidepressants amitriptyline, maprotiline, and fluoxetine on inhibitory avoidance state-dependent? Behavioural brain research, 2006, Jan-06, Volume: 166, Issue:1 Topics: Amitriptyline; Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Female; Fluoxetine; Inhibition, Psychological; Male; Maprotiline; Mice; Sex Factors	2006
Reduction of Submissive Behavior Model for antidepressant drug activity testing: study using a video-tracking system. Behavioural pharmacology, 2005, Volume: 16, Issue:8 Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Competitive Behavior; Dominance-Subordination; Feeding Behavior; Fluoxetine; Imipramine; Maprotiline; Mice; Naltrexone; Narcotic Antagonists; Rats	2005
Effects of noradrenaline and serotonin reuptake inhibitors on pituitary-adrenocortical and sympatho-adrenomedullar system of adult rats. Neuro endocrinology letters, 2007, Volume: 28, Issue:5 Topics: Adrenal Medulla; Adrenergic Uptake Inhibitors; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Corticosterone; Epinephrine; Fluoxetine; Hypothalamo-Hypophyseal System; Male; Maprotiline; Norepinephrine; Pituitary-Adrenal System; Random Allocation; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Sympathetic Nervous System	2007
Modelling the anxiety-depression continuum in chicks. Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:2 Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Chickens; Chlordiazepoxide; Clonidine; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxetine; Imipramine; Interleukin-6; Maprotiline; Social Isolation; Stress, Psychological	2009
Mouse strain differences in the unpredictable chronic mild stress: a four-antidepressant survey. Behavioural brain research, 2008, Nov-03, Volume: 193, Issue:1 Topics: Animals; Animals, Outbred Strains; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Chronic Disease; Depression; Desipramine; Fluoxetine; Grooming; Imipramine; Injections, Intraperitoneal; Male; Maprotiline; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Selective Serotonin Reuptake Inhibitors; Species Specificity; Stress, Psychological; Time Factors	2008
Lipidomic analyses of the mouse brain after antidepressant treatment: evidence for endogenous release of long-chain fatty acids? The international journal of neuropsychopharmacology, 2009, Volume: 12, Issue:7 Topics: Animals; Antidepressive Agents; Basal Ganglia; Brain; Ceramides; Cerebellum; Chromatography, High Pressure Liquid; Fatty Acids; Fluoxetine; Hippocampus; Injections, Intraperitoneal; Lysophospholipids; Male; Maprotiline; Mice; Mice, Inbred BALB C; Paroxetine; Phosphatidylcholines; Phospholipases A2; Prefrontal Cortex; Spectrometry, Mass, Electrospray Ionization; Sphingomyelins; Time Factors	2009
The antidepressants maprotiline and fluoxetine have potent selective antiproliferative effects against Burkitt lymphoma independently of the norepinephrine and serotonin transporters. Leukemia & lymphoma, 2010, Volume: 51, Issue:3 Topics: Animals; Antidepressive Agents; Apoptosis; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Fluoxetine; Humans; Leukemia; Leukocytes, Mononuclear; Maprotiline; Mice; Norepinephrine; Serotonin Plasma Membrane Transport Proteins	2010
The antidepressants maprotiline and fluoxetine induce Type II autophagic cell death in drug-resistant Burkitt's lymphoma. International journal of cancer, 2011, Apr-01, Volume: 128, Issue:7 Topics: Antidepressive Agents, Second-Generation; Apoptosis; Autophagy; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Burkitt Lymphoma; Calcium; Cell Death; Cell Line, Tumor; Cell Separation; Drug Resistance, Neoplasm; Flow Cytometry; Fluoxetine; Humans; Maprotiline; Microscopy, Confocal	2011
Effects of repeated maprotiline and fluoxetine treatment on gene expression of catecholamine synthesizing enzymes in adrenal medulla of unstressed and stressed rats. Autonomic & autacoid pharmacology, 2010, Volume: 30, Issue:4 Topics: Adrenal Medulla; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Dopamine beta-Hydroxylase; Epinephrine; Fluoxetine; Gene Expression Regulation, Enzymologic; Male; Maprotiline; Norepinephrine; Phenylethanolamine N-Methyltransferase; Random Allocation; Rats; Rats, Wistar; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Stress, Physiological; Stress, Psychological; Tyrosine 3-Monooxygenase	2010
Antidepressants that inhibit both serotonin and norepinephrine reuptake impair long-term potentiation in hippocampus. Psychopharmacology, 2014, Volume: 231, Issue:23 Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cyclohexanols; Fluoxetine; Hippocampus; Imipramine; Long-Term Potentiation; Male; Maprotiline; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptic Transmission; Venlafaxine Hydrochloride	2014