fluoxetine and ibuprofen

fluoxetine has been researched along with ibuprofen in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (20.00)29.6817
2010's23 (76.67)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Caron, G; Ermondi, G1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Buckley, DB; Funk, RS; Hensley, T; Kazmi, F; Loewen, GJ; Parkinson, A; Pope, C1
Bennis, K; Ducki, S; Lesage, F; Vivier, D1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Castle, DM; Johnson, DJ; Lam, M; Mabury, SA; Richards, SM; Sibley, PK; Solomon, KR; Wilson, CJ1
De Lange, HJ; Lürling, M; Murk, AJ; Noordoven, W; Peeters, ET1
André, C; Blaise, C; Gagné, F; Salazar, M1
Michael Saunders, F; Oh, D; Park, JJ; Reinhold, D; Vishwanathan, S1
Fernandes, D; Porte, C; Schnell, S1
Bragg, LM; Dixon, G; Oakes, KD; Pawliszyn, J; Servos, MR; Wang, S1
Bainy, AC; Bebianno, MJ; Gonzalez-Rey, M; Mattos, JJ; Piazza, CE1
Abd El-Samad, AA; El Gayar, NH; Hamza, M; Masoud, SI; Nasr, EA; Saleh, LA1
Budzinski, H; Choubert, JM; Coquery, M; Miège, C; Pomiès, M; Wisniewski, C1
Capela, JM; Cardoso, JL; de Moraes, NV; Lanchote, VL; Lepera, JS; Pereira, MP1
Brandão, ML; Carabelli, B; Cunha, JM; Cunha, TM; da Silva Dias, IC; de Carvalho, MC; de Morais, H; Ferraz, AC; Ishii, DK; Rizzo de Souza, LE; Zanata, SM; Zanoveli, JM1
Aliko, V; Faggio, C; Korriku, RS; Pagano, M1

Reviews

2 review(s) available for fluoxetine and ibuprofen

ArticleYear
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
    Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11

    Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship

2016
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

28 other study(ies) available for fluoxetine and ibuprofen

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells).
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4

    Topics: Adrenergic beta-Antagonists; Amines; Ammonium Chloride; Antidepressive Agents, Tricyclic; Atorvastatin; Cell Line, Transformed; Diuretics; Hepatocytes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imipramine; Lysosomes; Monensin; Nigericin; Propranolol; Pyrroles

2013
Effects of pharmaceutical mixtures in aquatic microcosms.
    Environmental toxicology and chemistry, 2004, Volume: 23, Issue:4

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Araceae; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Interactions; Ecosystem; Fishes; Fluoxetine; Food Chain; Ibuprofen; Multivariate Analysis; Phytoplankton; Population Dynamics; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Water Microbiology; Water Pollutants, Chemical; Zooplankton

2004
Behavioural responses of Gammarus pulex (Crustacea, Amphipoda) to low concentrations of pharmaceuticals.
    Aquatic toxicology (Amsterdam, Netherlands), 2006, Jun-30, Volume: 78, Issue:3

    Topics: Amphipoda; Analgesics, Non-Narcotic; Animals; Anticonvulsants; Antidepressive Agents, Second-Generation; Behavior, Animal; Carbamazepine; Cetrimonium; Cetrimonium Compounds; Dose-Response Relationship, Drug; Environmental Monitoring; Fluoxetine; Fresh Water; Ibuprofen; Lethal Dose 50; Motor Activity; Surface-Active Agents; Water Pollutants, Chemical

2006
Effects of pharmaceutical products and municipal wastewaters on temperature-dependent mitochondrial electron transport activity in Elliptio complanata mussels.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2006, Volume: 143, Issue:4

    Topics: Bivalvia; Caffeine; Carbamazepine; Cholestanol; Cotinine; Electron Transport; Fluoxetine; Ibuprofen; Lipid Peroxidation; Mitochondria; Novobiocin; Pharmaceutical Preparations; Sewage; Temperature; Trimethoprim; Xenobiotics

2006
Assessment of plant-driven removal of emerging organic pollutants by duckweed.
    Chemosphere, 2010, Volume: 80, Issue:7

    Topics: 2,4-Dichlorophenoxyacetic Acid; Araceae; Atrazine; Biodegradation, Environmental; Clofibric Acid; Cosmetics; DEET; Fluoxetine; Ibuprofen; Pesticides; Pharmaceutical Preparations; Picloram; Triclosan; Water Pollutants, Chemical; Wetlands

2010
Can pharmaceuticals interfere with the synthesis of active androgens in male fish? An in vitro study.
    Marine pollution bulletin, 2011, Volume: 62, Issue:10

    Topics: Androgens; Animals; Anti-Inflammatory Agents; Antidepressive Agents; Biomarkers; Carps; Clofibrate; Clofibric Acid; Diclofenac; Fibric Acids; Fluoxetine; Gemfibrozil; Ibuprofen; Male; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase; Testis; Water Pollutants, Chemical

2011
Validation and use of in vivo solid phase micro-extraction (SPME) for the detection of emerging contaminants in fish.
    Chemosphere, 2011, Volume: 85, Issue:9

    Topics: Animals; Atrazine; Benzhydryl Compounds; Carbamazepine; Diclofenac; Environmental Monitoring; Fishes; Fluoxetine; Gemfibrozil; Ibuprofen; Naproxen; Phenols; Solid Phase Extraction; Solid Phase Microextraction; Waste Disposal, Fluid; Water Pollutants, Chemical

2011
Effects of active pharmaceutical ingredients mixtures in mussel Mytilus galloprovincialis.
    Aquatic toxicology (Amsterdam, Netherlands), 2014, Volume: 153

    Topics: Animals; Biomarkers; Copper; Diclofenac; Enzyme Activation; Fluoxetine; Gene Expression Regulation, Enzymologic; Gills; Ibuprofen; Lipid Peroxidation; Mytilus; Oxidative Stress; Oxidoreductases; Water Pollutants, Chemical

2014
Ibuprofen suppresses depressive like behavior induced by BCG inoculation in mice: role of nitric oxide and prostaglandin.
    Pharmacology, biochemistry, and behavior, 2014, Volume: 125

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; BCG Vaccine; Brain Chemistry; Depression; Dinoprostone; Fluoxetine; Hippocampus; Ibuprofen; Male; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins

2014
Lab-scale experimental strategy for determining micropollutant partition coefficient and biodegradation constants in activated sludge.
    Environmental science and pollution research international, 2015, Volume: 22, Issue:6

    Topics: Aerobiosis; Anaerobiosis; Atenolol; Biodegradation, Environmental; Carbon; Denitrification; Diclofenac; Fluoxetine; Ibuprofen; Nitrification; Sewage; Wastewater; Water Pollutants, Chemical

2015
Impact of inhalational exposure to ethanol fuel on the pharmacokinetics of verapamil, ibuprofen and fluoxetine as in vivo probe drugs for CYP3A, CYP2C and CYP2D in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2015, Volume: 84

    Topics: Air Pollutants, Occupational; Animals; Aryl Hydrocarbon Hydroxylases; Atmosphere Exposure Chambers; Biofuels; Biomarkers; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inducers; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Fluoxetine; Ibuprofen; Inhalation Exposure; Limonene Hydroxylases; Male; Rats, Wistar; Toxicity Tests, Chronic; Verapamil

2015
Indoleamine-2,3-Dioxygenase/Kynurenine Pathway as a Potential Pharmacological Target to Treat Depression Associated with Diabetes.
    Molecular neurobiology, 2016, Volume: 53, Issue:10

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Blood Glucose; Cytokines; Depression; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fluoxetine; Hippocampus; Ibuprofen; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation Mediators; Kynurenine; Male; Minocycline; Molecular Targeted Therapy; Motor Activity; Norepinephrine; Rats, Wistar; Serotonin; Swimming; Tryptophan; Weight Gain

2016
Double-edged sword: Fluoxetine and ibuprofen as development jeopardizers and apoptosis' inducers in common toad, Bufo bufo, tadpoles.
    The Science of the total environment, 2021, Jul-01, Volume: 776

    Topics: Animals; Apoptosis; Bufo bufo; Fluoxetine; Ibuprofen; Larva; Water Pollutants, Chemical

2021