fluoxetine and gemfibrozil

fluoxetine has been researched along with gemfibrozil in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (14.29)29.6817
2010's17 (80.95)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Fernandes, D; Porte, C; Schnell, S1
Bragg, LM; Dixon, G; Oakes, KD; Pawliszyn, J; Servos, MR; Wang, S1
Higgins, S; Iftikar, FI; Irshad, A; Jandoc, R; Lee, M; Smith, EM; Wilson, JY1
Dowd, KE; Downing, SS; Duran, C; Eslamfam, S; Hoose, SA; Hoover, EM; Malik, I; Polymenis, M; Shasserre, SC; Smith, R1
Coleman, HM; Khan, SJ; Le-Clech, P; Stuetz, RM; Trinh, T; van den Akker, B1
Prosser, RS; Sibley, PK; Trapp, S1
Ribalta, C; Solé, M1
Gu, QY; Jiang, B; Ni, YF; Wang, FY; Wang, H; Wang, JL; Wang, YJ1
Doucette, WJ; Lombardero, LR; Pérez, DJ1

Reviews

1 review(s) available for fluoxetine and gemfibrozil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

20 other study(ies) available for fluoxetine and gemfibrozil

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Can pharmaceuticals interfere with the synthesis of active androgens in male fish? An in vitro study.
    Marine pollution bulletin, 2011, Volume: 62, Issue:10

    Topics: Androgens; Animals; Anti-Inflammatory Agents; Antidepressive Agents; Biomarkers; Carps; Clofibrate; Clofibric Acid; Diclofenac; Fibric Acids; Fluoxetine; Gemfibrozil; Ibuprofen; Male; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase; Testis; Water Pollutants, Chemical

2011
Validation and use of in vivo solid phase micro-extraction (SPME) for the detection of emerging contaminants in fish.
    Chemosphere, 2011, Volume: 85, Issue:9

    Topics: Animals; Atrazine; Benzhydryl Compounds; Carbamazepine; Diclofenac; Environmental Monitoring; Fishes; Fluoxetine; Gemfibrozil; Ibuprofen; Naproxen; Phenols; Solid Phase Extraction; Solid Phase Microextraction; Waste Disposal, Fluid; Water Pollutants, Chemical

2011
In vitro inhibition of cytochrome P450-mediated reactions by gemfibrozil, erythromycin, ciprofloxacin and fluoxetine in fish liver microsomes.
    Aquatic toxicology (Amsterdam, Netherlands), 2012, Volume: 109

    Topics: Animals; Ciprofloxacin; Cytochrome P-450 Enzyme System; Enzyme Activation; Erythromycin; Fish Proteins; Fluoxetine; Gemfibrozil; Microsomes, Liver; Oncorhynchus mykiss; Water Pollutants, Chemical; Zebrafish

2012
Systematic analysis of cell cycle effects of common drugs leads to the discovery of a suppressive interaction between gemfibrozil and fluoxetine.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Cell Cycle; Cell Proliferation; Drug Interactions; Flow Cytometry; Fluoxetine; Gemfibrozil; Mitosis

2012
Removal of trace organic chemical contaminants by a membrane bioreactor.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2012, Volume: 66, Issue:9

    Topics: Amitriptyline; Bioreactors; Carbamazepine; Diazepam; Diclofenac; Fluoxetine; Gemfibrozil; Omeprazole; Organic Chemicals; Pharmaceutical Preparations; Sulfamethoxazole; Trimethoprim; Waste Disposal, Fluid; Water Pollutants, Chemical

2012
Modeling uptake of selected pharmaceuticals and personal care products into food crops from biosolids-amended soil.
    Environmental science & technology, 2014, Oct-07, Volume: 48, Issue:19

    Topics: Agriculture; Carbamazepine; Carbanilides; Cimetidine; Cosmetics; Crops, Agricultural; Diphenhydramine; Fluoxetine; Gemfibrozil; Miconazole; Models, Theoretical; Pharmaceutical Preparations; Plant Roots; Plant Shoots; Sewage; Soil Pollutants; Triclosan

2014
In vitro interaction of emerging contaminants with the cytochrome p450 system of Mediterranean deep-sea fish.
    Environmental science & technology, 2014, Oct-21, Volume: 48, Issue:20

    Topics: Animals; Benzopyrans; Cytochrome P-450 Enzyme System; Diclofenac; Female; Fish Proteins; Fishes; Fluoxetine; Gemfibrozil; Male; Mediterranean Sea; Phenols; Triclosan; Water Pollutants, Chemical; Xenobiotics

2014
Gemfibrozil has antidepressant effects in mice: Involvement of the hippocampal brain-derived neurotrophic factor system.
    Journal of psychopharmacology (Oxford, England), 2018, Volume: 32, Issue:4

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Carbazoles; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Fenclonine; Fluoxetine; Gemfibrozil; Hippocampus; Immobility Response, Tonic; Indole Alkaloids; Male; Membrane Glycoproteins; Mice; Motor Activity; Oxazoles; Protein-Tyrosine Kinases; RNA, Small Interfering; Serotonin; Signal Transduction; Tyrosine

2018
Influence of exposure time, physicochemical properties, and plant transpiration on the uptake dynamics and translocation of pharmaceutical and personal care products in the aquatic macrophyte Typha latifolia.
    The Science of the total environment, 2023, Oct-20, Volume: 896

    Topics: Carbamazepine; Chromatography, Liquid; Cosmetics; Fluoxetine; Gemfibrozil; Pharmaceutical Preparations; Plant Transpiration; Tandem Mass Spectrometry; Triclosan; Typhaceae; Water Pollutants, Chemical

2023