fluoxetine and gamma-aminobutyric acid

fluoxetine has been researched along with gamma-aminobutyric acid in 60 studies

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-19903 (5.00)18.7374
1990's10 (16.67)18.2507
2000's23 (38.33)29.6817
2010's21 (35.00)24.3611
2020's3 (5.00)2.80

Authors

AuthorsStudies
Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM1
Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L1
Anderson, GM; Craig, JS; During, MJ; Gallager, DW; Hernandez, TD1
Iovino, M; Maj, M; Monteleone, P; Steardo, L1
Colmers, WF; Pan, ZZ; Williams, JT1
Lloyd, KG; Pilc, A; Thuret, F1
Aghajanian, GK; De Montigny, C; Reader, TA; Wang, RY1
Goodwin, WB; Guyenet, PG; Huangfu, D1
Gale, K; Pasini, A; Tortorella, A1
Cooper, TB; Costa, E; Guidotti, A; Uzunov, DP1
Corá-Locatelli, G; Greenberg, BD; Martin, JD; Murphy, DL1
Matthews, J; Pollack, MH; Scott, EL1
Corá-Locatelli, G; Greenberg, BD; Martin, J; Murphy, DL1
Crites, GJ; Goldenberg, R; Malatynska, E; Schindler, NL; Tunnicliff, G; Yochum, A1
Churchill, LE; Connor, KM; Davidson, JR; Foa, EB1
Drafts, BC; Fisher, JL; Robinson, RT1
Bernardi, G; di Michele, F; Pace, M; Pasinib, A; Pompili, E; Romeo, E; Rupprecht, R1
Christodoulou, GN; Dimopoulos, NP; Gitsa, OE; Liappas, AI; Liappas, IA; Malitas, PN; Nikolaou, CK1
Chan, W; Yen, HL1
Hemrick-Luecke, SK; Iyengar, S; Simmons, RM; Webster, AA; Xu, JY1
Chopde, CT; Hirani, K; Mittal, N; Ugale, RR1
Yan, Z; Zhong, P1
Forray, MI; Gysling, K; Sotomayor, R1
Akaike, A; Katsuki, H1
Blackburn-Munro, G; Nielsen, AN; Pedersen, LH1
Anglard, P; Aunis, D; Burgun, C; Carouge, D; Cassel, S; Dietrich, JB; Gensburger, C; Zwiller, J1
Fonteles, MM; Freitas, RM; Sousa, FC; Viana, GS1
Davies, M; Derry, JM; Dunn, SM; Paulsen, IM1
Alexander, IM; Moore, A1
Berkman, K; Gören, MZ; Küçükibrahimoglu, E; Terzioglu, B1
Gökbakan, M; Onder, E; Tural, U1
Baroncelli, L; Castrén, E; De Pasquale, R; Maffei, L; Maya Vetencourt, JF; O'Leary, OF; Sale, A; Viegi, A1
Xu, TL; Ye, ZY; Zhou, JN; Zhou, KQ1
Costa, E; Guidotti, A; Pinna, G1
Calişkan, M; Gören, MZ; Kaplan, OK; Küçükibrahimoğlu, E; Saygin, MZ; Unsal, C1
Aharoni, A; Geffen, Y; Gil-Ad, I; Halbfinger, E; Nisemblat, Y; Nudelman, A; Rephaeli, A; Tarasenko, I; Tarasenko, N; Weizman, A1
Egeland, M; Greengard, P; Svenningsson, P; Warner-Schmidt, J1
Choi, HC; Kang, TC; Kim, DS; Kim, JE; Kim, YI; Song, HK1
Dempsey, CM; Griffin, CT; Hapiak, VM; Komuniecki, RW; Kuan, CJ; Kullyev, A; Miller, S; Sze, JY1
MacGregor, EA1
Bain, MJ; Fan, CM1
Girbig, D; Igl, BW; Lehmann, T; Obendorf, M; Patchev, VK; Prelle, K1
Abdel-Daiem, WM; Abdel-Sater, KA; Sayyed Bakheet, M1
Bacci, A; Méndez, P; Pazienti, A; Szabó, G1
Iwanaga, T; Miyakawa, T; Ohira, K; Takeuchi, R1
Baroncelli, L; Begenisic, T; Bonanno, G; Bonifacino, T; Cioni, G; Maffei, L; Milanese, M; Sale, A; Sansevero, G1
Gao, X; Qiao, M; Sun, P; Wei, S; Xue, L; Zhang, H1
Pehrson, AL; Sanchez, C1
Denenberg, S1
Oflaz, S; Soyata, AZ1
Ghorbani, R; Mohseni, A; Rahmanian, M1
André, E; de Sousa Pinto, ÍA; Gavioli, EC; Lovick, T; Santos, RO; Soares-Rachetti, Vde P1
DuBois, DW; Fincher, AS; Frye, GD; Henry, MM; Morgan, C; Shannonhouse, JL; Vela, AM; Wellman, PJ1
Nudmamud-Thanoi, S; Roboon, J; Thanoi, S1
Chung, SK; Lam, LC; Ma, SL; So, KF; Tsim, KW; Wong, YH; Yeung, PK; Zhou, L1
Flais, I; Lazarevic, V; Mantas, I; Svenningsson, P1
Di, T; Guo, J; Guo, X; Li, P; Liu, Y; Meng, Y; Qi, C; Wang, Y; Zhang, L; Zhao, J1
Chen, S; Chen, Z; Feng, P; Gu, J; Lin, S; Tao, Y; Wang, P; Xu, H; Xu, Z; Zhao, J1
Chi, X; Lu, Y; Ma, K; Pan, J; Shi, H; Wang, Y; Wu, J; Xue, X; Zhang, Z1

Reviews

5 review(s) available for fluoxetine and gamma-aminobutyric acid

ArticleYear
The role of receptor binding in drug discovery.
    Journal of natural products, 1993, Volume: 56, Issue:4

    Topics: Animals; Drug Design; Humans; Receptors, Drug

1993
Treating vasomotor symptoms of menopause: the nurse practitioner's perspective.
    Journal of the American Academy of Nurse Practitioners, 2007, Volume: 19, Issue:3

    Topics: Adrenergic alpha-Agonists; Algorithms; Amines; Citalopram; Clonidine; Complementary Therapies; Cyclohexanecarboxylic Acids; Estrogen Replacement Therapy; Evidence-Based Medicine; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Life Style; Menopause; Middle Aged; Nurse Practitioners; Paroxetine; Patient Education as Topic; Patient Selection; Practice Guidelines as Topic; Primary Health Care; Safety Management; Selective Serotonin Reuptake Inhibitors

2007
SSRIs act as selective brain steroidogenic stimulants (SBSSs) at low doses that are inactive on 5-HT reuptake.
    Current opinion in pharmacology, 2009, Volume: 9, Issue:1

    Topics: Animals; Brain; Fluoxetine; gamma-Aminobutyric Acid; Humans; Mental Disorders; Mood Disorders; Pregnanolone; Receptors, GABA-A; Selective Serotonin Reuptake Inhibitors; Social Isolation; Synaptic Transmission

2009
Perimenopausal migraine in women with vasomotor symptoms.
    Maturitas, 2012, Volume: 71, Issue:1

    Topics: Amines; Cyclohexanecarboxylic Acids; Estrogen Replacement Therapy; Estrogens; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Migraine Disorders; Neurotransmitter Agents; Perimenopause

2012
Altered γ-aminobutyric acid neurotransmission in major depressive disorder: a critical review of the supporting evidence and the influence of serotonergic antidepressants.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Animals; Antidepressive Agents; Brain; Depressive Disorder, Major; Evidence-Based Medicine; Fluoxetine; GABA Agents; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neural Inhibition; Piperazines; Selective Serotonin Reuptake Inhibitors; Serotonin; Sulfides; Synaptic Transmission; Vortioxetine

2015

Trials

4 trial(s) available for fluoxetine and gamma-aminobutyric acid

ArticleYear
Gabapentin augmentation for fluoxetine-treated patients with obsessive-compulsive disorder.
    The Journal of clinical psychiatry, 1998, Volume: 59, Issue:9

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Obsessive-Compulsive Disorder; Pilot Projects; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

1998
Effects of fluoxetine, indomethacine and placebo on 3 alpha, 5 alpha tetrahydroprogesterone (THP) plasma levels in uncomplicated alcohol withdrawal.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2000, Volume: 1, Issue:2

    Topics: Adult; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Ethanol; Fluoxetine; gamma-Aminobutyric Acid; Humans; Indomethacin; Male; Pregnanolone; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome

2000
Does gabapentin lead to early symptom improvement in obsessive-compulsive disorder?
    European archives of psychiatry and clinical neuroscience, 2008, Volume: 258, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Amines; Analysis of Variance; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Young Adult

2008
A crossover study comparing gabapentin and fluoxetine for the treatment of vasomotor symptoms among postmenopausal women.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015, Volume: 131, Issue:1

    Topics: Amines; Cross-Over Studies; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Iran; Middle Aged; Postmenopause; Selective Serotonin Reuptake Inhibitors; Surveys and Questionnaires; Sweating; Treatment Outcome

2015

Other Studies

51 other study(ies) available for fluoxetine and gamma-aminobutyric acid

ArticleYear
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
    Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

    Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship

2013
Effect of amygdala kindling on the in vivo release of GABA and 5-HT in the dorsal raphe nucleus in freely moving rats.
    Brain research, 1992, Jul-03, Volume: 584, Issue:1-2

    Topics: Amino Acids; Amygdala; Animals; Dialysis; Fluoxetine; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Nipecotic Acids; Potassium; Proline; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tetrodotoxin; Veratridine

1992
GABA, depression and the mechanism of action of antidepressant drugs: a neuroendocrine approach.
    Journal of affective disorders, 1990, Volume: 20, Issue:1

    Topics: Adult; Amitriptyline; Antidepressive Agents; Baclofen; Brain; Depressive Disorder; Fluoxetine; gamma-Aminobutyric Acid; Growth Hormone; Humans; Imipramine; Male; Middle Aged; Personality Tests; Receptors, GABA-A

1990
5-HT-mediated synaptic potentials in the dorsal raphe nucleus: interactions with excitatory amino acid and GABA neurotransmission.
    Journal of neurophysiology, 1989, Volume: 62, Issue:2

    Topics: Animals; Electric Stimulation; Fluoxetine; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Neurons; Pons; Raphe Nuclei; Rats; Serotonin; Spiperone; Synapses

1989
Upregulation of gamma-aminobutyric acid (GABA) B binding sites in rat frontal cortex: a common action of repeated administration of different classes of antidepressants and electroshock.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:1

    Topics: Animals; Antidepressive Agents; Cerebral Cortex; Desipramine; Dose-Response Relationship, Drug; Electroshock; Fluoxetine; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Male; Monoamine Oxidase Inhibitors; Nomifensine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin Antagonists; Time Factors; Viloxazine

1985
Monoaminergic denervation of the rat hippocampus: microiontophoretic studies on pre- and postsynaptic supersensitivity to norepinephrine and serotonin.
    Brain research, 1980, Nov-03, Volume: 200, Issue:2

    Topics: Animals; Denervation; Desipramine; Dihydroxytryptamines; Fluoxetine; gamma-Aminobutyric Acid; Hippocampus; Hydroxydopamines; Isoproterenol; Locus Coeruleus; Male; Norepinephrine; Rats; Serotonin; Synapses

1980
Sympatholytic effect of tricyclic antidepressants: site and mechanism of action in anesthetized rats.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 2

    Topics: Adrenergic alpha-Antagonists; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Baclofen; Blood Pressure; Brain Mapping; Desipramine; Dioxanes; Fluoxetine; gamma-Aminobutyric Acid; Idazoxan; Imidazoles; Male; Medulla Oblongata; Microinjections; Nordefrin; Oxidopamine; Rats; Rats, Sprague-Dawley; Splanchnic Nerves; Sympatholytics; Time Factors

1995
The anticonvulsant action of fluoxetine in substantia nigra is dependent upon endogenous serotonin.
    Brain research, 1996, Jun-10, Volume: 724, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anticonvulsants; Bicuculline; Convulsants; Fenclonine; Fluoxetine; gamma-Aminobutyric Acid; Male; Microinjections; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Seizures; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Substantia Nigra

1996
Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Oct-29, Volume: 93, Issue:22

    Topics: 20-alpha-Dihydroprogesterone; Adrenalectomy; Animals; Brain; Castration; Fluoxetine; GABA Modulators; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Imipramine; Male; Paroxetine; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley

1996
Rebound psychiatric and physical symptoms after gabapentin discontinuation.
    The Journal of clinical psychiatry, 1998, Volume: 59, Issue:3

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Obsessive-Compulsive Disorder; Recurrence; Substance Withdrawal Syndrome

1998
Gabapentin as a potential treatment for anxiety disorders.
    The American journal of psychiatry, 1998, Volume: 155, Issue:7

    Topics: Acetates; Adult; Alprazolam; Amines; Anticonvulsants; Anxiety Disorders; Cyclohexanecarboxylic Acids; Diazepam; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Panic Disorder; Phobic Disorders

1998
The GABA(A) receptor complex as a target for fluoxetine action.
    Neurochemical research, 1999, Volume: 24, Issue:10

    Topics: Animals; Chlorides; Dose-Response Relationship, Drug; Flunitrazepam; Fluoxetine; gamma-Aminobutyric Acid; Ion Transport; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Selective Serotonin Reuptake Inhibitors; Tritium

1999
Treating hot flashes with drugs: an update.
    Harvard women's health watch, 2002, Volume: 9, Issue:12

    Topics: Acetates; Amines; Anticonvulsants; Antidepressive Agents, Second-Generation; Antihypertensive Agents; Clonidine; Cyclohexanecarboxylic Acids; Cyclohexanols; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Venlafaxine Hydrochloride

2002
Hyperhidrosis in social anxiety disorder.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:7-8

    Topics: Acetates; Adult; Amines; Calcium Channel Blockers; Clinical Trials as Topic; Clonazepam; Cognitive Behavioral Therapy; Cyclohexanecarboxylic Acids; Female; Fluoxetine; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperhidrosis; Male; Phobic Disorders; Prognosis; Retrospective Studies; Selective Serotonin Reuptake Inhibitors

2002
Fluoxetine increases GABA(A) receptor activity through a novel modulatory site.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 304, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; gamma-Aminobutyric Acid; Mammals; Receptors, GABA-A; Recombinant Proteins; Selective Serotonin Reuptake Inhibitors

2003
Three cases of zolpidem dependence treated with fluoxetine: the serotonin hypothesis.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2003, Volume: 4, Issue:2

    Topics: Adult; Female; Fluoxetine; GABA Agonists; gamma-Aminobutyric Acid; Humans; Male; Pyridines; Selective Serotonin Reuptake Inhibitors; Serotonin; Substance-Related Disorders; Treatment Outcome; Zolpidem

2003
An East-West approach to the management of central post-stroke pain.
    Cerebrovascular diseases (Basel, Switzerland), 2003, Volume: 16, Issue:1

    Topics: Acetates; Acupuncture; Aged; Amines; Amitriptyline; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Pain; Pain Management; Physical Therapy Modalities; Stroke; Tramadol; Triazines

2003
Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:2

    Topics: Acute Disease; Amines; Amitriptyline; Animals; Conscious Sedation; Cyclohexanecarboxylic Acids; Cyclohexanols; Cyclopropanes; Disease Models, Animal; Drug Therapy, Combination; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Methyltyrosines; Milnacipran; Neuromuscular Junction; Norepinephrine; p-Chloroamphetamine; Pain; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Thiophenes; Venlafaxine Hydrochloride

2004
Essentiality of central GABAergic neuroactive steroid allopregnanolone for anticonvulsant action of fluoxetine against pentylenetetrazole-induced seizures in mice.
    Brain research, 2004, Oct-08, Volume: 1023, Issue:1

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; gamma-Aminobutyric Acid; Male; Mice; Pentylenetetrazole; Pregnanolone; Seizures

2004
Chronic antidepressant treatment alters serotonergic regulation of GABA transmission in prefrontal cortical pyramidal neurons.
    Neuroscience, 2004, Volume: 129, Issue:1

    Topics: Animals; Antidepressive Agents; Evoked Potentials; Fluoxetine; gamma-Aminobutyric Acid; Organ Culture Techniques; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Time Factors

2004
Acute morphine administration increases extracellular DA levels in the rat lateral septum by decreasing the GABAergic inhibitory tone in the ventral tegmental area.
    Journal of neuroscience research, 2005, Jul-01, Volume: 81, Issue:1

    Topics: Analysis of Variance; Animals; Dopamine; Drug Administration Schedule; Extracellular Fluid; Fluoxetine; gamma-Aminobutyric Acid; Male; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neural Inhibition; Neural Pathways; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Septum of Brain; Serotonin; Statistics, Nonparametric; Ventral Tegmental Area

2005
Quinolinic acid toxicity on orexin neurons blocked by gamma aminobutyric acid type A receptor stimulation.
    Neuroreport, 2005, Aug-01, Volume: 16, Issue:11

    Topics: Animals; Animals, Newborn; Bicuculline; Cell Count; Citalopram; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Magnesium; Neurons; Neuropeptides; Nipecotic Acids; Norepinephrine; Orexin Receptors; Orexins; Organophosphorus Compounds; Picrotoxin; Quinolinic Acid; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, GABA-A; Receptors, Neuropeptide; Selective Serotonin Reuptake Inhibitors; Serotonin

2005
Anti-nociception is selectively enhanced by parallel inhibition of multiple subtypes of monoamine transporters in rat models of persistent and neuropathic pain.
    Psychopharmacology, 2005, Volume: 182, Issue:4

    Topics: Amines; Analgesics; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Bupropion; Constriction; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Male; Morpholines; Motor Activity; Neurotransmitter Uptake Inhibitors; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reboxetine; Rotarod Performance Test; Spinal Cord Injuries; Vesicular Monoamine Transport Proteins

2005
Fluoxetine and cocaine induce the epigenetic factors MeCP2 and MBD1 in adult rat brain.
    Molecular pharmacology, 2006, Volume: 70, Issue:2

    Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cocaine; DNA-Binding Proteins; Epigenesis, Genetic; Fluoxetine; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Methyl-CpG-Binding Protein 2; Rats; Rats, Wistar; RNA, Messenger; Serotonin

2006
Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus.
    Neuroscience letters, 2006, Nov-13, Volume: 408, Issue:2

    Topics: Amines; Amitriptyline; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Male; Muscarinic Agonists; N-Methylaspartate; Pilocarpine; Pimozide; Rats; Seizures; Status Epilepticus

2006
A single point mutation of the GABA(A) receptor alpha5-subunit confers fluoxetine sensitivity.
    Neuropharmacology, 2007, Volume: 52, Issue:2

    Topics: Amino Acid Substitution; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Fluoxetine; GABA Agonists; gamma-Aminobutyric Acid; Isoxazoles; Membrane Potentials; Models, Molecular; Mutagenesis; Mutation; Oocytes; Patch-Clamp Techniques; Protein Subunits; Receptors, GABA-A; Recombinant Proteins; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Xenopus laevis

2007
Fluoxetine partly exerts its actions through GABA: a neurochemical evidence.
    Neurochemical research, 2007, Volume: 32, Issue:9

    Topics: Animals; Fluoxetine; gamma-Aminobutyric Acid; Glutamic Acid; Male; Rats; Rats, Sprague-Dawley

2007
The antidepressant fluoxetine restores plasticity in the adult visual cortex.
    Science (New York, N.Y.), 2008, Apr-18, Volume: 320, Issue:5874

    Topics: Amblyopia; Animals; Antidepressive Agents, Second-Generation; Brain-Derived Neurotrophic Factor; Diazepam; Dominance, Ocular; Evoked Potentials, Visual; Fluoxetine; gamma-Aminobutyric Acid; Long-Term Potentiation; Long-Term Synaptic Depression; Neuronal Plasticity; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptic Transmission; Visual Cortex

2008
Fluoxetine potentiates GABAergic IPSCs in rat hippocampal neurons.
    Neuroscience letters, 2008, Sep-05, Volume: 442, Issue:1

    Topics: Animals; Cells, Cultured; Fluoxetine; gamma-Aminobutyric Acid; Hippocampus; Inhibitory Postsynaptic Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Synaptic Transmission

2008
The change in plasma GABA, glutamine and glutamate levels in fluoxetine- or S-citalopram-treated female patients with major depression.
    European journal of clinical pharmacology, 2009, Volume: 65, Issue:6

    Topics: Antidepressive Agents, Second-Generation; Case-Control Studies; Chromatography, High Pressure Liquid; Citalopram; Depression; Female; Fluoxetine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans

2009
Gamma-aminobutyric acid amides of nortriptyline and fluoxetine display improved pain suppressing activity.
    Journal of medicinal chemistry, 2009, May-14, Volume: 52, Issue:9

    Topics: Analgesics; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Fluoxetine; Formaldehyde; gamma-Aminobutyric Acid; Inflammation; Male; Mice; Nortriptyline; Pain; Rats

2009
Neurogenic effects of fluoxetine are attenuated in p11 (S100A10) knockout mice.
    Biological psychiatry, 2010, Jun-01, Volume: 67, Issue:11

    Topics: Analysis of Variance; Animals; Annexin A2; Behavior, Animal; Cell Proliferation; Cell Survival; Fluoxetine; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; In Situ Hybridization; Male; Mice; Mice, Knockout; Microscopy, Fluorescence; Neurogenesis; Neuronal Plasticity; Neurons; S100 Proteins; Selective Serotonin Reuptake Inhibitors

2010
Effects of selective serotonin reuptake inhibitors on GABAergic inhibition in the hippocampus of normal and pilocarpine induced epileptic rats.
    Brain research, 2010, Oct-21, Volume: 1357

    Topics: Analysis of Variance; Animals; Citalopram; Electroencephalography; Epilepsy; Fluoxetine; gamma-Aminobutyric Acid; Hippocampus; Male; Neural Inhibition; Neurons; Paroxetine; Pilocarpine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Vesicular Inhibitory Amino Acid Transport Proteins

2010
A genetic survey of fluoxetine action on synaptic transmission in Caenorhabditis elegans.
    Genetics, 2010, Volume: 186, Issue:3

    Topics: Acetylcholine; Animals; Behavior, Animal; Biological Assay; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Fluoxetine; gamma-Aminobutyric Acid; Glutamic Acid; Muscle Relaxation; Mutation; Neurons; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Signal Transduction; Synaptic Transmission

2010
Animal behavior case of the month. Motivation for the tail-chasing behavior was considered to most likely be multifactorial.
    Journal of the American Veterinary Medical Association, 2012, Mar-15, Volume: 240, Issue:6

    Topics: Acepromazine; Amines; Animals; Anticonvulsants; Behavior, Animal; Compulsive Behavior; Cyclohexanecarboxylic Acids; Displacement, Psychological; Dog Diseases; Dogs; Dopamine Antagonists; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Selective Serotonin Reuptake Inhibitors

2012
Endpoints of drug discovery for menopausal vasomotor symptoms: interpretation of data from a proxy of disease.
    Menopause (New York, N.Y.), 2012, Volume: 19, Issue:8

    Topics: Acetamides; Amines; Animals; Body Temperature Regulation; Cyclohexanecarboxylic Acids; Cyclohexanols; Disease Models, Animal; Diurnal Enuresis; Drug Discovery; Estradiol; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Hypnotics and Sedatives; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Skin Temperature; Venlafaxine Hydrochloride

2012
The gender difference of selective serotonin reuptake inhibitor, fluoxetine in adult rats with stress-induced gastric ulcer.
    European journal of pharmacology, 2012, Aug-05, Volume: 688, Issue:1-3

    Topics: Animals; Catalase; Cerebral Cortex; Female; Fluoxetine; gamma-Aminobutyric Acid; Gastric Mucosa; Male; Malondialdehyde; Nitric Oxide; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Sex Characteristics; Stomach; Stomach Ulcer; Stress, Psychological

2012
Direct alteration of a specific inhibitory circuit of the hippocampus by antidepressants.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Nov-21, Volume: 32, Issue:47

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Biogenic Monoamines; CA1 Region, Hippocampal; Data Interpretation, Statistical; Electroencephalography; Evoked Potentials; Excitatory Postsynaptic Potentials; Female; Fluoxetine; gamma-Aminobutyric Acid; Hippocampus; Imipramine; Inhibition, Psychological; Interneurons; Male; Nerve Net; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Selective Serotonin Reuptake Inhibitors; Synaptic Transmission

2012
Chronic fluoxetine treatment reduces parvalbumin expression and perineuronal nets in gamma-aminobutyric acidergic interneurons of the frontal cortex in adult mice.
    Molecular brain, 2013, Nov-05, Volume: 6

    Topics: Aging; Animals; Apoptosis; CA3 Region, Hippocampal; Calbindin 2; Cell Count; Fluoxetine; Frontal Lobe; GABAergic Neurons; gamma-Aminobutyric Acid; Interneurons; Male; Mice; Mice, Inbred C57BL; Models, Biological; Parvalbumins; Somatostatin; Thalamus

2013
Fluoxetine in adulthood normalizes GABA release and rescues hippocampal synaptic plasticity and spatial memory in a mouse model of Down syndrome.
    Neurobiology of disease, 2014, Volume: 63

    Topics: Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Biophysics; Disease Models, Animal; Down Syndrome; Electric Stimulation; Fluoxetine; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Recognition, Psychology; Space Perception; Synaptosomes

2014
Shu‑Yu capsule, a Traditional Chinese Medicine formulation, attenuates premenstrual syndrome depression induced by chronic stress constraint.
    Molecular medicine reports, 2014, Volume: 10, Issue:6

    Topics: Animals; Body Mass Index; Depression; Drugs, Chinese Herbal; Female; Fluoxetine; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Medicine, Chinese Traditional; Oleanolic Acid; Premenstrual Syndrome; Rats; Rats, Wistar; Saponins

2014
Animal behavior case of the month. Tail chasing in a dog diagnosed as compulsive disorder.
    Journal of the American Veterinary Medical Association, 2015, May-01, Volume: 246, Issue:9

    Topics: Amines; Animals; Anticonvulsants; Behavior, Animal; Bites and Stings; Cyclohexanecarboxylic Acids; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Tail

2015
Gabapentin Treatment in Bruxism Associated With Fluoxetine.
    Journal of clinical psychopharmacology, 2015, Volume: 35, Issue:4

    Topics: Adult; Amines; Bruxism; Cyclohexanecarboxylic Acids; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2015
Short term, low dose fluoxetine blocks estrous cycle-linked changes in responsiveness to diazepam in female rats.
    Journal of psychopharmacology (Oxford, England), 2016, Volume: 30, Issue:10

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Brain; Diazepam; Estrous Cycle; Estrus; Female; Fluoxetine; gamma-Aminobutyric Acid; Locomotion; Maze Learning; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Selective Serotonin Reuptake Inhibitors; Serotonin

2016
Fluoxetine disrupts motivation and GABAergic signaling in adolescent female hamsters.
    Progress in neuro-psychopharmacology & biological psychiatry, 2016, 08-01, Volume: 69

    Topics: Anhedonia; Animals; Anxiety; Brain-Derived Neurotrophic Factor; Conflict, Psychological; Cricetinae; Exploratory Behavior; Feeding Behavior; Female; Fluoxetine; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Motivation; Neuronal Plasticity; Nucleus Accumbens; Receptors, GABA-A; Reward; RNA, Messenger; Sexual Maturation; Tissue Culture Techniques

2016
Recovery effect of pre-germinated brown rice on the alteration of sperm quality, testicular structure and androgen receptor expression in rat model of depression.
    Andrologia, 2017, Volume: 49, Issue:1

    Topics: Animals; Antidepressive Agents; Depressive Disorder; Disease Models, Animal; Fluoxetine; gamma-Aminobutyric Acid; Male; Oryza; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Sperm Motility; Spermatozoa; Swimming; Testis

2017
Anxiety and depression with neurogenesis defects in exchange protein directly activated by cAMP 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, Prozac.
    Translational psychiatry, 2016, 09-06, Volume: 6, Issue:9

    Topics: Affect; Aged; Aged, 80 and over; Alzheimer Disease; Animals; Anxiety; Asian People; Behavior, Animal; Cyclic AMP; Depression; Female; Fluoxetine; gamma-Aminobutyric Acid; Guanine Nucleotide Exchange Factors; Hippocampus; Humans; Male; Mice, Knockout; Neurogenesis; Restraint, Physical; Selective Serotonin Reuptake Inhibitors; Stress, Psychological

2016
Fluoxetine Suppresses Glutamate- and GABA-Mediated Neurotransmission by Altering SNARE Complex.
    International journal of molecular sciences, 2019, Aug-30, Volume: 20, Issue:17

    Topics: Animals; Calcium Channels; Exocytosis; Female; Fluoxetine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Models, Neurological; Presynaptic Terminals; Protein Kinase C; Rats, Wistar; SNARE Proteins; Synaptic Transmission

2019
Depressive-like behaviors in mice with Imiquimod-induced psoriasis.
    International immunopharmacology, 2020, Volume: 89, Issue:Pt B

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Brain; Cytokines; Depression; Disease Models, Animal; Epinephrine; Exploratory Behavior; Fluoxetine; Food Preferences; gamma-Aminobutyric Acid; Imiquimod; Male; Mice, Inbred BALB C; Neurotransmitter Agents; Norepinephrine; Open Field Test; Psoriasis; Serotonin; Skin

2020
Saffron essential oil ameliorates CUMS-induced depression-like behavior in mice via the MAPK-CREB1-BDNF signaling pathway.
    Journal of ethnopharmacology, 2023, Jan-10, Volume: 300

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Crocus; Depression; Disease Models, Animal; Dopamine; Eosine Yellowish-(YS); Fluoxetine; gamma-Aminobutyric Acid; Hematoxylin; Hippocampus; MAP Kinase Signaling System; Mice; Neuroprotective Agents; Oils, Volatile; Serotonin; Signal Transduction; Stress, Physiological; Stress, Psychological; Sucrose

2023
Mechanism of lily bulb and Rehmannia decoction in the treatment of lipopolysaccharide-induced depression-like rats based on metabolomics study and network pharmacology.
    Pharmaceutical biology, 2022, Volume: 60, Issue:1

    Topics: Animals; Antidepressive Agents; Cytokines; Depression; Drugs, Chinese Herbal; Endocannabinoids; Fluoxetine; gamma-Aminobutyric Acid; Glycosylphosphatidylinositols; Hormones; Interleukin-6; Lilium; Lipopolysaccharides; Metabolomics; Network Pharmacology; Plant Extracts; Rats; Rehmannia; Serotonin; Tumor Necrosis Factor-alpha

2022