fluoxetine and fenfluramine

fluoxetine has been researched along with fenfluramine in 132 studies

Research

Studies (132)

TimeframeStudies, this research(%)All Research%
pre-199026 (19.70)18.7374
1990's76 (57.58)18.2507
2000's25 (18.94)29.6817
2010's4 (3.03)24.3611
2020's1 (0.76)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Quock, RM; Weick, BG1
Sanders-Bush, E; Steranka, LR1
Clineschmidt, BV; McGuffin, JC1
Clineschmidt, BV; McGuffin, JC; Pflueger, AB; Totaro, JA; Wishousky, TI; Zacchei, AG1
Dawsey, WJ; Geyer, MA; Mandell, AJ1
Górka, Z; Kwiatek, H; Maj, J; Wojtasik, E1
Silverstone, T1
Bizzi, A; Caccia, S; Garattini, S; Mennini, T1
Azmitia, EC; Berger, UV; Gu, XF1
Li, ET; Luo, S1
Asin, KE; Bednarz, L; Davis, JD1
Abercrombie, ED; Jackson, D1
Kriete, M; Rapoport, JL; Ryland, DH1
Anthony, DT; Fallon, BA; Hollander, E; Klein, DF; Liebowitz, MR; Schneier, FR; Stein, DJ1
Fisher, H; Lu, MR; Wagner, GC3
Dinan, TG; McLoughlin, D; O'Keane, V1
Richards, JB; Sabol, KE; Seiden, LS2
Frittoli, E; Garattini, S; Gobbi, M; Mennini, T1
McGuirk, J; Muscat, R; Willner, P1
Gleason, R; Morse, AN; Sarkissian, CF; Wurtman, RJ1
Gardier, AM; Wurtman, RJ1
Hodge, J; Munro, JF; Scott, C1
Black, CK; Fadayel, GM; Kehne, JH; McCloskey, TC; Schmidt, CJ; Taylor, VL1
Brammer, GL; McGuire, MT; Pollack, DB; Raleigh, MJ; Yuwiler, A1
Meinders, AE1
Koppeschaar, HP; Meinders, AE; Pijl, H; Zelissen, PM1
Li, ET; Luo, SQ2
DeCaria, CM; Hollander, E; Klein, DF; Liebowitz, MR; Schneier, FR; Schneier, HA1
McGuirk, J; Muscat, R; Phillips, G; Willner, P1
Fuller, RW; Robertson, DW; Snoddy, HD1
Auerbach, SB; Minzenberg, MJ; Wilkinson, LO1
Cooper, SJ; Neill, JC2
Kim, SH; Wurtman, RJ1
Bethea, CL; Richardson, KD; Urban, JH; Van de Kar, LD1
Fuller, RW1
Richardson, KD; Urban, JH; Van de Kar, LD1
Lalonde, R; Vikis-Freibergs, V1
Fornal, C; Radulovacki, M1
Bardakdjian, J; Costa, MF; Fages, C; Gonnard, P; Tardy, M1
McElroy, JF; Meyer, JS; Miller, JM1
Feldman, RS; McElroy, JF1
Fuller, RW; Snoddy, HD1
Dumbrille-Ross, A; Tang, SW1
Appel, JB; White, FJ1
Du Pont, AF; Feldman, RS; McElroy, JF1
Broekkamp, CL; Garrigou, D; LLoyd, KG1
Hutson, PH; Knott, PJ1
Dalló, J; Knoll, J; Yen, TT1
Buitrago, F; Díaz Pérez de Madrid, J; Mendoza Espejo, R1
el-Khoury, A; Goldberg, H; McDermott, J; Pingitore, R; Spring, B; Wurtman, J; Wurtman, R1
McCann, UD; Ricaurte, GA; Yuan, J1
Crespi, D; Gobbi, M; Mennini, T1
Day, J; Fibiger, HC; Hirano, H1
Auerbach, SB; Rutter, JJ1
Borve, T; Fisher, H; Johnson, SK; Pole, N; Wagner, GC1
Bonanno, G; Raiteri, M; Vallebuona, F1
Bell, RC; Campbell, TC; Frongillo, EA; Lanou, AJ; Levitsky, DA1
Brownfield, MS; Levy, AD; Li, Q; Rittenhouse, PA; Van de Kar, LD1
Bertrand, J; Costentin, J; Simon, P1
Azmitia, EC; Leonardi, ET1
Snyman, JR; Sommers, DK; van Wyk, M1
Bonanno, G; Fassio, A; Raiteri, M; Ruelle, A; Severi, P1
Chambers, JW; Coscina, DV; Currie, PJ; Fletcher, PJ1
Holtzman, SG; Steinfels, GF1
Berry, E; Gleason, R; Goldberg, H; Kahne, M; McDermott, J; Tsay, R; Wurtman, J; Wurtman, R1
Maj, J; Moryl, E1
Adler, L; Huether, G; Poeggeler, B; Rüther, E1
Duhault, J; Espinal, J; Lacour, F; Rolland, Y1
Emsley, RA; Jordaan, GP; Roberts, MC1
Avanzini, P; Caccavari, R; Delsignore, R; Fertonani, G; Gerra, G; Lucchini, A; Rota-Graziosi, I; Zaimovic, A1
Carpenter, LL; Epperson, CN; McDougle, CJ; Price, LH1
Hatzidimitriou, G; McCann, UD; Ricaurte, GA1
Halpern, A; Lima, N; Medeiros-Neto, G; Pedrinola, F; Sztejnsznajd, C1
Schechter, MD1
Curzon, G; Gibson, EL; Oluyomi, AO1
Anchors, M1
Bowyer, JF; Clausing, P; Newport, GD; Rushing, LG1
Abdeen, MA; Frishman, WH; Michaelson, MD; Weiser, M1
Anelli, M; Bergami, A; Caccia, S; Confalonieri, S; Fracasso, C; Garattini, S1
Heal, DJ; Hutchins, LJ; Jackson, HC; Mazurkiewicz, SE; Needham, AM1
Auerbach, SB; Gundlah, C; Heal, DJ; Martin, KF1
Boyd, LD; Dwyer, JT; Papas, A1
Coccaro, EF; Hauger, RL; Kavoussi, RJ2
Erfurth, A; Wurtman, RJ1
Gray, TS; Javed, A; Van De Kar, LD1
Njo, L; Rich, JM; Roberts, KW; Smith, KP1
Darmani, NA1
Coscina, DV; Currie, PJ; Fletcher, PJ1
Borrell, L; Foreyt, JP; Haddock, CK; Poston, WS1
Costall, B; Neill, JC; Wilson, AW1
Ayestas, MA; Baumann, MH; Rothman, RB1
Bengel, D; Heils, A; Isaacs, KR; Lesch, KP; Murphy, DL1
Cowley, G; Springen, K1
Campbell, TC; King, JM; Levitsky, DA; Lin, X1
Mitropoulou, V; New, AS; Reynolds, D; Schopick, F; Siever, LJ; Silverman, J; Trestman, RL; Woo-Ming, A1
Knobelman, DA; Kung, HF; Lucki, I1
Henderson, DR; Konkle, DM; Mitchell, GS1
Antonelli, T; Bebe, BW; Ferraro, L; Fuxe, K; Rambert, FA; Tanganelli, S; Tomasini, MC1
Cooper, J; Greenslade, RG; Mitchell, SN1
Yan, QS1
Anwyl, R; Rowan, MJ; Shakesby, AC1
Aspley, S; Auerbach, S; Brammer, R; Fray, A; Heal, D; Tao, R1
Subramanian, S; Vollmer, RR2
Hallas, BH; Horowitz, JM; Torres, G1
Burmeister, JJ; Lungren, EM; Neisewander, JL1
Badauê-Passos, D; Olivares, EL; Reis, LC; Silva, LF; Ventura, RR1
Jones, SL; Miller, DK; Wellman, PJ1
Pan, WJ; Song, HR; Wang, F; Wang, YL; Wu, CF; Yang, JY1
Dunlop, PC; Johnson, GJ; Leis, LA; Weir, EK1
Barnes, NM; Blakely, RD; Bunce, CM; Challa, A; Chamba, A; Drake-Lee, A; Drayson, MT; Dyer, MJ; Gordon, J; Holder, MJ; Meredith, EJ; Pilkington, G1
Bertrand, PP; Chavez, C; Gogos, A; Jones, M; Paranavitane, UT; van den Buuse, M1
Atkinson, RL; Dhurandhar, NV; Rahko, PS; Whigham, LD1
Lim, DS; Welch, JT1
Baumann, MH; Rothman, RB; Zolkowska, D1
Amitani, H; Asakawa, A; Fujimiya, M; Fujitsuka, N; Hayashi, M; Inui, A; Kojima, S; Sameshima, M1
Ayala, ME1
Hazell, P; Silove, N; Wheeler, DM; Williams, K1
Goodman, MM; Howell, LL; Kimmel, HL; Mun, J; Nye, JA; Rice, KC; Sawyer, EK; Stehouwer, JS; Voll, RJ1
Brignell, A; Hazell, P; Randall, M; Silove, N; Williams, K1
Albakry, A; Aminov, S; Bodnar, RJ; Fazylov, D; Jean-Philippe-Morisset, B; Lulu, EB; Macanian, J; Mustac, T; Nashed, M; Yuabov, A1

Reviews

11 review(s) available for fluoxetine and fenfluramine

ArticleYear
Progress report on the anorectic effects of dexfenfluramine, fluoxetine and sertraline.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1992, Volume: 16 Suppl 3

    Topics: 1-Naphthylamine; Animals; Appetite Depressants; Brain; Eating; Fenfluramine; Fluoxetine; Humans; Serotonin; Serotonin Antagonists; Sertraline

1992
Appraisal of the clinical value of serotoninergic drugs.
    The American journal of clinical nutrition, 1992, Volume: 55, Issue:1 Suppl

    Topics: Appetite Depressants; Fenfluramine; Fluoxetine; Humans; Obesity; Serotonin; Weight Loss

1992
Very low calorie diets and recently developed anti-obesity drugs for treating overweight in non-insulin-dependent diabetics.
    The Netherlands journal of medicine, 1990, Volume: 37, Issue:3-4

    Topics: Adrenergic beta-Agonists; Diabetes Mellitus, Type 2; Diet, Reducing; Fenfluramine; Fluoxetine; Humans; Obesity

1990
[Regulation of food intake and the treatment of obesity using centrally-active serotonergic drugs].
    Nederlands tijdschrift voor geneeskunde, 1991, Apr-20, Volume: 135, Issue:16

    Topics: Adult; Energy Intake; Energy Metabolism; Female; Fenfluramine; Fluoxetine; Humans; Male; Middle Aged; Obesity; Serotonin

1991
Biochemical pharmacology of the serotonin system.
    Advances in neurology, 1986, Volume: 43

    Topics: Alanine; Brain; Citalopram; Clomipramine; Fenfluramine; Fluoxetine; Fluvoxamine; Humans; Monoamine Oxidase Inhibitors; Neurons; Oximes; p-Chloroamphetamine; Paroxetine; Piperidines; Propylamines; Receptors, Serotonin; Reserpine; Serotonin; Serotonin Antagonists; Synapses; Tetrabenazine; Zimeldine

1986
A risk-benefit assessment of drugs used in the management of obsessive-compulsive disorder.
    Drug safety, 1996, Volume: 15, Issue:2

    Topics: 1-Naphthylamine; Adult; Aged; Antidepressive Agents; Buspirone; Child; Clomipramine; Clonazepam; Costs and Cost Analysis; Dopamine Antagonists; Drug Interactions; Drug Tolerance; Fenfluramine; Fluoxetine; Fluvoxamine; Humans; Lithium; Obsessive-Compulsive Disorder; Paroxetine; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Sertraline; Tryptophan

1996
Appetite suppression by commonly used drugs depends on 5-HT receptors but not on 5-HT availability.
    Trends in pharmacological sciences, 1997, Volume: 18, Issue:1

    Topics: Appetite Depressants; Body Weight; Brain; Dopamine Agonists; Eating; Female; Fenfluramine; Fluoxetine; Humans; Male; Neuropeptide Y; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Agents

1997
The pharmacologic approach to the treatment of obesity.
    Journal of clinical pharmacology, 1997, Volume: 37, Issue:6

    Topics: Adrenergic beta-Agonists; Appetite Depressants; Cardiovascular Diseases; Cyclobutanes; Energy Metabolism; Fenfluramine; Fluoxetine; Humans; Obesity

1997
Challenges in obesity management.
    Southern medical journal, 1998, Volume: 91, Issue:8

    Topics: 1-Naphthylamine; Adrenergic beta-Agonists; Appetite Depressants; Behavior Therapy; Caffeine; Cyclobutanes; Diethylpropion; Ephedrine; Fenfluramine; Fluoxetine; Humans; Lactones; Leptin; Lipase; Obesity; Orlistat; Phentermine; Proteins; Sertraline

1998
Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD).
    The Cochrane database of systematic reviews, 2010, Aug-04, Issue:8

    Topics: Adult; Age Factors; Autistic Disorder; Child; Citalopram; Fenfluramine; Fluoxetine; Fluvoxamine; Humans; Obsessive-Compulsive Disorder; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors

2010
Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD).
    The Cochrane database of systematic reviews, 2013, Aug-20, Issue:8

    Topics: Adult; Age Factors; Autistic Disorder; Child; Child Development Disorders, Pervasive; Citalopram; Fenfluramine; Fluoxetine; Fluvoxamine; Humans; Obsessive-Compulsive Disorder; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors

2013

Trials

10 trial(s) available for fluoxetine and fenfluramine

ArticleYear
Drug treatment of canine acral lick. An animal model of obsessive-compulsive disorder.
    Archives of general psychiatry, 1992, Volume: 49, Issue:7

    Topics: 1-Naphthylamine; Animals; Clomipramine; Dermatitis; Desipramine; Disease Models, Animal; Dog Diseases; Dogs; Double-Blind Method; Fenfluramine; Fluoxetine; Follow-Up Studies; Grooming; Humans; Neurotransmitter Uptake Inhibitors; Obsessive-Compulsive Disorder; Serotonin; Sertraline; Ulcer

1992
D-fenfluramine-induced prolactin and cortisol release in major depression: response to treatment.
    Journal of affective disorders, 1992, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Amitriptyline; Depressive Disorder; Electroconvulsive Therapy; Female; Fenfluramine; Fluoxetine; Humans; Hydrocortisone; Male; Middle Aged; Personality Inventory; Prognosis; Prolactin; Receptors, Serotonin; Serotonin

1992
[Effectiveness of serotonergic agonists in the treatment of obese patients].
    Atencion primaria, 1995, Oct-15, Volume: 16, Issue:6

    Topics: Adult; Appetite Depressants; Body Mass Index; Diet, Reducing; Female; Fenfluramine; Fluoxetine; Follow-Up Studies; Humans; Male; Middle Aged; Obesity; Serotonin Receptor Agonists; Time Factors

1995
Efficacies of dexfenfluramine and fluoxetine in preventing weight gain after smoking cessation.
    The American journal of clinical nutrition, 1995, Volume: 62, Issue:6

    Topics: Adult; Analysis of Variance; Appetite Depressants; Body Mass Index; Dietary Carbohydrates; Dietary Proteins; Double-Blind Method; Feeding Behavior; Female; Fenfluramine; Fluoxetine; Humans; Obesity; Selective Serotonin Reuptake Inhibitors; Smoking Cessation; Surveys and Questionnaires; Survival Analysis; Weight Gain

1995
Dexfenfluramine-induced prolactin release as an index of central synaptosomal 5-hydroxytryptamine during treatment with fluoxetine.
    European journal of clinical pharmacology, 1994, Volume: 46, Issue:5

    Topics: Adult; Central Nervous System; Fenfluramine; Fluoxetine; Humans; Male; Prolactin; Receptors, Serotonin; Serotonin; Single-Blind Method; Synaptosomes

1994
Hostility in heroin abusers subtypes: fluoxetine and naltrexone treatment.
    Progress in neuro-psychopharmacology & biological psychiatry, 1995, Volume: 19, Issue:8

    Topics: Adult; Aggression; Antidepressive Agents, Second-Generation; Fenfluramine; Fluoxetine; Heroin Dependence; Hostility; Humans; Male; Naltrexone; Narcotic Antagonists; Neurosecretory Systems; Psychiatric Status Rating Scales; Treatment Outcome

1995
The addition of dexfenfluramine to fluoxetine in the treatment of obesity: a randomized clinical trial.
    Obesity research, 1996, Volume: 4, Issue:6

    Topics: Adult; Aged; Body Mass Index; Drug Therapy, Combination; Female; Fenfluramine; Fluoxetine; Humans; Lipids; Male; Middle Aged; Obesity, Morbid; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Treatment Outcome; Weight Loss

1996
Serotonin function and antiaggressive response to fluoxetine: a pilot study.
    Biological psychiatry, 1997, Oct-01, Volume: 42, Issue:7

    Topics: Adolescent; Adolescent Behavior; Adult; Aggression; Double-Blind Method; Fenfluramine; Fluoxetine; Humans; Male; Mood Disorders; Personality Disorders; Pilot Projects; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Serotonin

1997
Prolactin response to d-fenfluramine in major depression before and after treatment with serotonin reuptake inhibitors.
    Biological psychiatry, 1999, Feb-01, Volume: 45, Issue:3

    Topics: Adult; Analysis of Variance; Depressive Disorder; Double-Blind Method; Female; Fenfluramine; Fluoxetine; Fluvoxamine; Humans; Male; Prolactin; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Time Factors

1999
Serotonin and the prediction of response time to fluoxetine in patients with mild depression.
    Psychiatry research, 1999, Nov-08, Volume: 88, Issue:2

    Topics: Adult; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Double-Blind Method; Female; Fenfluramine; Fluoxetine; Humans; Male; Predictive Value of Tests; Prolactin; Remission Induction; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Severity of Illness Index; Treatment Outcome

1999

Other Studies

111 other study(ies) available for fluoxetine and fenfluramine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
p-Chloroamphetamine-induced hyperthermia pharmacologically distinct from fenfluramine-induced hyperthermia.
    The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:1

    Topics: Amphetamines; Animals; Body Temperature; Brain Stem; Cyproheptadine; Fenclonine; Fenfluramine; Fluoxetine; Haloperidol; Hydrazines; Lysergic Acid Diethylamide; Male; Metergoline; p-Chloroamphetamine; Rabbits; Serotonin; Time Factors

1979
Long-term effects of fenfluramine on central serotonergic mechanisms.
    Neuropharmacology, 1979, Volume: 18, Issue:11

    Topics: Animals; Brain; Catecholamines; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Male; Rats; Serotonin; Tryptophan Hydroxylase

1979
Pharmacological differentiation of the central 5-hydroxytryptamine-like actions of MK-212 (6-chloro-2[1-piperazinyl]-pyrazine),p-methoxyamphetamine and fenfluramine in an in vivo model system.
    European journal of pharmacology, 1978, Aug-15, Volume: 50, Issue:4

    Topics: Amphetamines; Animals; Dextroamphetamine; Drug Interactions; Fenclonine; Fenfluramine; Fluoxetine; In Vitro Techniques; Male; Metergoline; Muscle Contraction; Piperazines; Pyrazines; Rats; Serotonin; Time Factors

1978
Fenfluramine and brain serotonin.
    Annals of the New York Academy of Sciences, 1978, Jun-12, Volume: 305

    Topics: 5-Hydroxytryptophan; Aging; Animals; Animals, Newborn; Brain; Dealkylation; Dihydroxyphenylalanine; Female; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Rats; Serotonin; Time Factors

1978
Fading: a new cytofluorimetric measure quantifying serotonin in the presence of catecholamines at the cellular level in brain.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 207, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Brain Mapping; Clomipramine; Dopamine; Extracellular Space; Fenfluramine; Fluoxetine; Histocytochemistry; Lysergic Acid Diethylamide; Male; Norepinephrine; Pargyline; Rats; Serotonin; Spectrometry, Fluorescence

1978
Action of serotoninmimetics in the behavioral despair test in rats.
    Communications in psychopharmacology, 1979, Volume: 3, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Haloperidol; Imipramine; Immobilization; Lysergic Acid Diethylamide; Premedication; Quipazine; Rats; Receptors, Serotonin; Serotonin

1979
Drugs, serotonin and appetite control in humans.
    Clinical neuropharmacology, 1992, Volume: 15 Suppl 1 Pt A

    Topics: Animals; Appetite; Fenfluramine; Fluoxetine; Rats; Serotonin; Serotonin Antagonists; Synaptic Transmission

1992
The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine.
    European journal of pharmacology, 1992, May-14, Volume: 215, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Calcium; Cocaine; Fenfluramine; Fluoxetine; In Vitro Techniques; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; p-Chloroamphetamine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptosomes

1992
Effect of 5-HT agonists on rats fed single diets with varying proportions of carbohydrate and protein.
    Psychopharmacology, 1992, Volume: 109, Issue:1-2

    Topics: Animals; Dietary Carbohydrates; Dietary Proteins; Dose-Response Relationship, Drug; Eating; Fenfluramine; Fluoxetine; Indoles; Male; Rats; Rats, Wistar; Serotonin Receptor Agonists

1992
Differential effects of serotonergic and catecholaminergic drugs on ingestive behavior.
    Psychopharmacology, 1992, Volume: 109, Issue:4

    Topics: Animals; Dextroamphetamine; Eating; Fenfluramine; Fluoxetine; Male; Parasympathomimetics; Phenylpropanolamine; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists

1992
In vivo neurochemical evaluation of striatal serotonergic hyperinnervation in rats depleted of dopamine at infancy.
    Journal of neurochemistry, 1992, Volume: 58, Issue:3

    Topics: Animals; Animals, Newborn; Biogenic Amines; Corpus Striatum; Dialysis; Dopamine; Extracellular Space; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Potassium; Rats; Rats, Inbred Strains; Serotonin

1992
Serotonergic medications for sexual obsessions, sexual addictions, and paraphilias.
    The Journal of clinical psychiatry, 1992, Volume: 53, Issue:8

    Topics: Adolescent; Adult; Behavior, Addictive; Clomipramine; Fenfluramine; Fluoxetine; Fluvoxamine; Humans; Male; Middle Aged; Neurotransmitter Uptake Inhibitors; Obsessive-Compulsive Disorder; Paraphilic Disorders; Psychiatric Status Rating Scales; Retrospective Studies; Serotonin

1992
Ethanol intake of chickens treated with fenfluramine, fluoxetine, and dietary tryptophan.
    Alcoholism, clinical and experimental research, 1992, Volume: 16, Issue:5

    Topics: Alcohol Drinking; Animals; Body Temperature Regulation; Brain; Chickens; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Male; Receptors, Serotonin; Serotonin; Taste; Tryptophan

1992
Fluoxetine attenuates the DL-fenfluramine-induced increase in extracellular serotonin as measured by in vivo dialysis.
    Brain research, 1992, Jul-10, Volume: 585, Issue:1-2

    Topics: Animals; Dialysis; Extracellular Space; Fenfluramine; Fluoxetine; Hippocampus; Male; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists

1992
Releasing activities of d-fenfluramine and fluoxetine on rat hippocampal synaptosomes preloaded with [3H]serotonin.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:1

    Topics: Animals; Calcium; Chromatography, High Pressure Liquid; Fenfluramine; Fluoxetine; Hippocampus; Male; Rats; Reserpine; Serotonin; Serotonin Antagonists; Synaptosomes

1992
Effects of chronically administered fluoxetine and fenfluramine on food intake, body weight and the behavioural satiety sequence.
    Psychopharmacology, 1992, Volume: 106, Issue:3

    Topics: Animals; Behavior, Animal; Body Weight; Feeding Behavior; Fenfluramine; Fluoxetine; Grooming; Male; Motor Activity; Rats; Satiety Response; Substance Withdrawal Syndrome

1992
Effects of fluoxetine or D-fenfluramine on serotonin release from, and levels in, rat frontal cortex.
    Brain research, 1990, Oct-08, Volume: 529, Issue:1-2

    Topics: Animals; Cerebral Cortex; Dialysis; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Kinetics; Male; Rats; Rats, Inbred Strains; Reference Values; Serotonin

1990
Persistent blockade of potassium-evoked serotonin release from rat frontocortical terminals after fluoxetine administration.
    Brain research, 1991, Feb-01, Volume: 540, Issue:1-2

    Topics: Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Male; Potassium Chloride; Rats; Rats, Inbred Strains; Reference Values; Serotonin

1991
Effects of the serotonin releasers 3,4-methylenedioxymethamphetamine (MDMA), 4-chloroamphetamine (PCA) and fenfluramine on acoustic and tactile startle reflexes in rats.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Animals; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Indenes; Male; N-Methylaspartate; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Reflex, Acoustic; Reflex, Startle; Serotonin; Touch

1992
Serotonergic mechanisms promote dominance acquisition in adult male vervet monkeys.
    Brain research, 1991, Sep-20, Volume: 559, Issue:2

    Topics: Aggression; Animals; Behavior, Animal; Chlorocebus aethiops; Cyproheptadine; Fenfluramine; Fluoxetine; Male; Serotonin; Social Dominance; Tryptophan

1991
Effects of repeated administration of serotonergic agonists on diet selection and body weight in rats.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:3

    Topics: Animals; Body Weight; Diet; Drug Administration Schedule; Fenfluramine; Fluoxetine; Indoles; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin

1991
Fenfluramine augmentation of serotonin reuptake blockade antiobsessional treatment.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:3

    Topics: Adult; Clomipramine; Drug Administration Schedule; Drug Therapy, Combination; Female; Fenfluramine; Fluoxetine; Fluvoxamine; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Oximes; Serotonin Antagonists

1990
Behavioural analysis of the anorectic effects of fluoxetine and fenfluramine.
    Psychopharmacology, 1990, Volume: 102, Issue:2

    Topics: Animals; Appetite Depressants; Conditioning, Operant; Dose-Response Relationship, Drug; Drinking; Feeding Behavior; Fenfluramine; Fluoxetine; Grooming; Male; Rats; Reinforcement Schedule; Satiety Response; Sucrose

1990
Food intake and selection pattern of rats treated with dexfenfluramine, fluoxetine and RU 24969.
    Brain research bulletin, 1990, Volume: 24, Issue:6

    Topics: Animals; Feeding Behavior; Fenfluramine; Fluoxetine; Indoles; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin

1990
Mechanisms of effects of d-fenfluramine on brain serotonin metabolism in rats: uptake inhibition versus release.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:3

    Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Animals; Brain; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Kinetics; Male; Rats; Rats, Inbred Strains; Reference Values; Serotonin

1988
Extracellular serotonin and 5-hydroxyindoleacetic acid in hypothalamus of the unanesthetized rat measured by in vivo dialysis coupled to high-performance liquid chromatography with electrochemical detection: dialysate serotonin reflects neuronal release.
    Brain research, 1989, Oct-16, Volume: 499, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Hypothalamus; Male; Rats; Serotonin

1989
Selective reduction by serotonergic agents of hypertonic saline consumption in rats: evidence for possible 5-HT1C receptor mediation.
    Psychopharmacology, 1989, Volume: 99, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Drinking Behavior; Fenfluramine; Fluoxetine; Hypertonic Solutions; Indoles; Male; Piperazines; Pyrazines; Quinoxalines; Quipazine; Rats; Receptors, Serotonin; Serotonin

1989
Selective effects of CGS 10686B, dl-fenfluramine or fluoxetine on nutrient selection.
    Physiology & behavior, 1988, Volume: 42, Issue:4

    Topics: Animals; Brain; Dietary Carbohydrates; Dietary Proteins; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Food Preferences; Organic Chemicals; Propylamines; Rats; Receptors, Serotonin; Serotonin Antagonists; Synaptic Transmission

1988
Pharmacological studies on the serotoninergic and nonserotonin-mediated stimulation of prolactin and corticosterone secretion by fenfluramine. Effects of pretreatment with fluoxetine, indalpine, PCPA, and L-tryptophan.
    Neuroendocrinology, 1985, Volume: 41, Issue:4

    Topics: Animals; Antidepressive Agents; Corticosterone; Fenclonine; Fenfluramine; Fluoxetine; Kinetics; Male; Piperidines; Prolactin; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1985
Evidence for serotonergic modulation of sucrose sham-feeding in the gastric-fistulated rat.
    Physiology & behavior, 1988, Volume: 44, Issue:4-5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Eating; Fenfluramine; Fluoxetine; Male; Neurons; Quipazine; Rats; Rats, Inbred Strains; Satiation; Satiety Response; Serotonin; Stomach; Taste; Tetrahydronaphthalenes

1988
Serotonin and norepinephrine-dependent effects of fenfluramine on plasma renin activity in conscious male rats.
    Neuropharmacology, 1985, Volume: 24, Issue:6

    Topics: Animals; Blood Pressure; Desipramine; Dose-Response Relationship, Drug; Fenclonine; Fenfluramine; Fluoxetine; Heart Rate; Male; Norepinephrine; Piperidines; Rats; Rats, Inbred Strains; Renin; Serotonin; Serotonin Antagonists; Time Factors; Tryptophan

1985
Manipulations of 5-HT activity and memory in the rat.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Avoidance Learning; Drug Interactions; Fenfluramine; Fluoxetine; Imipramine; Lithium; Male; Memory; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tranylcypromine

1985
Sleep suppressant action of fenfluramine in rats. II. Evidence against the involvement of presynaptic serotonergic mechanism.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:3

    Topics: Animals; Electroencephalography; Fenclonine; Fenfluramine; Fluoxetine; Male; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Sleep; Synapses; Wakefulness

1983
Uptake and binding of serotonin by primary cultures of mouse astrocytes.
    Developmental neuroscience, 1982, Volume: 5, Issue:1

    Topics: Animals; Astrocytes; Bucladesine; Cell Membrane; Cells, Cultured; Clomipramine; Fenfluramine; Fluoxetine; Kinetics; Mice; Serotonin

1982
Fenfluramine, p-chloroamphetamine and p-fluoroamphetamine stimulation of pituitary-adrenocortical activity in rat: evidence for differences in site and mechanism of action.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 228, Issue:3

    Topics: Adrenocorticotropic Hormone; Amphetamines; Animals; Corticosterone; Fenfluramine; Fluoxetine; Male; Methysergide; p-Chloroamphetamine; Pituitary-Adrenal System; Rats; Receptors, Serotonin; Serotonin

1984
Discriminative stimulus properties of fenfluramine: evidence for serotonergic involvement.
    Psychopharmacology, 1984, Volume: 83, Issue:2

    Topics: Amphetamine; Analysis of Variance; Animals; Cues; Discrimination Learning; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Generalization, Stimulus; Male; Rats; Receptors, Serotonin; Satiation; Stereoisomerism

1984
Effect of serotonin-releasing drugs on serum corticosterone concentration in rats.
    Neuroendocrinology, 1980, Volume: 31, Issue:2

    Topics: Amphetamines; Animals; Corticosterone; Fenclonine; Fenfluramine; Fluoxetine; Male; p-Chloroamphetamine; Quipazine; Rats; Serotonin

1980
Manipulations of synaptic serotonin: discrepancy of effects on serotonin S1 and S2 sites.
    Life sciences, 1983, Jun-06, Volume: 32, Issue:23

    Topics: Animals; Cerebral Cortex; Fenfluramine; Fluoxetine; Male; Rats; Receptors, Serotonin; Serotonin; Spiperone; Tryptophan

1983
A neuropharmacological analysis of the discriminative stimulus properties of fenfluramine.
    Psychopharmacology, 1981, Volume: 73, Issue:2

    Topics: Animals; Cocaine; Cues; Discrimination, Psychological; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Hallucinogens; Lisuride; Lysergic Acid Diethylamide; Male; p-Chloroamphetamine; Piperazines; Pyrazines; Quipazine; Rats; Serotonin; Serotonin Antagonists

1981
The effects of fenfluramine and fluoxetine on the acquisition of the conditioned avoidance response in rats.
    Psychopharmacology, 1982, Volume: 77, Issue:4

    Topics: Analysis of Variance; Animals; Avoidance Learning; Conditioning, Psychological; Fenfluramine; Fluoxetine; Male; Propylamines; Rats; Rats, Inbred Strains; Serotonin

1982
Serotonin-mimetic and antidepressant drugs on passive avoidance learning by olfactory bulbectomised rats.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 13, Issue:5

    Topics: Animals; Antidepressive Agents; Avoidance Learning; Clonidine; Ergolines; Fenfluramine; Fluoxetine; Imipramine; Male; Metergoline; Mianserin; Olfactory Bulb; Quipazine; Rats; Serotonin; Serotonin Antagonists

1980
Stress-induced stereotypy in the rat: neuropharmacological similarities to Tourette syndrome.
    Advances in neurology, 1982, Volume: 35

    Topics: Animals; Disease Models, Animal; Fenfluramine; Fluoxetine; Humans; Male; Nervous System; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Rodent Diseases; Stereotyped Behavior; Stress, Physiological; Tourette Syndrome

1982
The selectivity of the anorectic effect of satietin. IV. The ineffectiveness of satietin on the sexual performance of male CFY rats.
    Polish journal of pharmacology and pharmacy, 1982, Volume: 34, Issue:1-3

    Topics: Amphetamine; Animals; Appetite Depressants; Copulation; Fenfluramine; Fluoxetine; Glycopeptides; Male; Rats; Time Factors

1982
Fenfluramine's appetite suppression and serotonin neurotoxicity are separable.
    European journal of pharmacology, 1995, Sep-05, Volume: 283, Issue:1-3

    Topics: Animals; Anorexia; Appetite; Body Weight; Drug Combinations; Eating; Fenfluramine; Fluoxetine; Male; Rats; Rats, Sprague-Dawley; Serotonin; Time Factors

1995
Effects of fluoxetine on basal and K(+)-induced tritium release from synaptosomes preloaded with [3H]serotonin.
    Life sciences, 1995, Volume: 56, Issue:10

    Topics: Animals; Cerebral Cortex; Fenfluramine; Fluoxetine; Hippocampus; Hydroxyindoleacetic Acid; Male; Pargyline; Potassium; Rats; Serotonin; Spinal Cord; Synaptosomes; Tritium

1995
Serotonergic regulation of acetylcholine release in rat frontal cortex.
    Journal of neurochemistry, 1995, Volume: 65, Issue:3

    Topics: Acetylcholine; Animals; Benzazepines; Dialysis; Fenfluramine; Fluoxetine; Frontal Lobe; Ketanserin; Kinetics; Male; Rats; Rats, Wistar; Serotonin

1995
Acute uptake inhibition increases extracellular serotonin in the rat forebrain.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:3

    Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Diencephalon; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Male; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline

1993
Effects of monoaminergic agonists on alcohol-induced increases in mouse aggression.
    Journal of studies on alcohol. Supplement, 1993, Volume: 11

    Topics: Aggression; Animals; Behavior, Animal; Brain; Drug Synergism; Ethanol; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Male; Mice; Tryptophan

1993
In vitro and in vivo effects of d-fenfluramine: no apparent relation between 5-hydroxytryptamine release and hypophagia.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:2

    Topics: Animals; Eating; Fenfluramine; Fluoxetine; Hypothalamus; In Vitro Techniques; Male; Metergoline; Microdialysis; Rats; Rats, Sprague-Dawley; Serotonin; Synaptosomes

1995
Accuracy and reliability of total body electrical conductivity (TOBEC) for determining body composition of rats in experimental studies.
    Physiology & behavior, 1994, Volume: 56, Issue:4

    Topics: Adipose Tissue; Animals; Body Composition; Body Weight; Dose-Response Relationship, Drug; Electric Conductivity; Female; Fenfluramine; Fluoxetine; Male; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Reference Values; Regression Analysis; Reproducibility of Results; Signal Processing, Computer-Assisted

1994
Hypothalamic paraventricular, but not supraoptic neurons, mediate the serotonergic stimulation of oxytocin secretion.
    Brain research bulletin, 1995, Volume: 36, Issue:1

    Topics: Animals; Fenfluramine; Fluoxetine; Ibotenic Acid; Male; Neurons; Oxytocin; p-Chloroamphetamine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Serotonin; Supraoptic Nucleus

1995
5-HT1A receptor blockade increases penile erections induced by indirect serotonin agonists.
    Neuroreport, 1993, Dec-13, Volume: 5, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Drug Synergism; Fenfluramine; Fluoxetine; Labetalol; Male; Penile Erection; Piperazines; Propanolamines; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes

1993
MDMA (ecstasy) inhibition of MAO type A and type B: comparisons with fenfluramine and fluoxetine (Prozac).
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1994, Volume: 10, Issue:4

    Topics: Animals; Binding, Competitive; Brain; Drug Interactions; Fenfluramine; Fluoxetine; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; N-Methyl-3,4-methylenedioxyamphetamine; Phenethylamines; Rats; Rats, Sprague-Dawley; Serotonin

1994
Fluoxetine (Prozac) and other drugs for treatment of obesity.
    The Medical letter on drugs and therapeutics, 1994, Nov-25, Volume: 36, Issue:936

    Topics: Clinical Trials as Topic; Drug Therapy, Combination; Fenfluramine; Fluoxetine; Humans; Obesity; Phentermine

1994
Fenfluramine releases serotonin from human brain nerve endings by a dual mechanism.
    Journal of neurochemistry, 1994, Volume: 63, Issue:3

    Topics: Calcium; Cerebral Cortex; Fenfluramine; Fluoxetine; Humans; Nerve Endings; Serotonin; Sumatriptan; Synaptosomes; Tritium

1994
Radiofrequency lesions of the PVN fail to modify the effects of serotonergic drugs on food intake.
    Brain research, 1993, Dec-10, Volume: 630, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Weight; Clonidine; Feeding Behavior; Fenfluramine; Fluoxetine; Male; Paraventricular Hypothalamic Nucleus; Piperazines; Radio Waves; Rats; Rats, Sprague-Dawley

1993
Ethanol consumption following acute treatment with methysergide, fluoxetine, fenfluramine, and their combination.
    Alcoholism, clinical and experimental research, 1994, Volume: 18, Issue:1

    Topics: Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Male; Methysergide; Rats; Rats, Sprague-Dawley; Serotonin; Synaptic Transmission

1994
Monoamine systems in the discriminative effects of spiradoline, a kappa-opioid agonist.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:3

    Topics: Analgesics; Animals; Avoidance Learning; Biogenic Monoamines; Discrimination, Psychological; Dopamine Antagonists; Fenfluramine; Fluoxetine; Generalization, Stimulus; Ketanserin; Male; Piperidines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptic Transmission

1994
Fluoxetine prevents the disruptive effects of fenfluramine on differential-reinforcement-of-low-rate 72-second schedule performance.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Fenfluramine; Fluoxetine; Male; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Serotonin; Time Factors

1993
Dexfenfluramine, fluoxetine, and weight loss among female carbohydrate cravers.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1993, Volume: 9, Issue:3

    Topics: Adult; Dietary Carbohydrates; Dietary Proteins; Eating; Female; Fenfluramine; Fluoxetine; Humans; Motor Activity; Weight Loss

1993
Effects of fluoxetine given chronically on the responsiveness of 5-HT receptor subpopulations to their agonists.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1993, Volume: 3, Issue:2

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Temperature; Exploratory Behavior; Fenfluramine; Fluoxetine; Male; Mice; Motor Activity; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists

1993
Effects of indirectly acting 5-HT receptor agonists on circulating melatonin levels in rats.
    European journal of pharmacology, 1993, Jul-20, Volume: 238, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Fenfluramine; Fluoxetine; Injections, Intraperitoneal; Male; Melatonin; Pargyline; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Selegiline; Serotonin Receptor Agonists; Tryptophan

1993
Ethanol consumption following acute fenfluramine, fluoxetine, and dietary tryptophan.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:4

    Topics: Alcohol Drinking; Animals; Diet; Dose-Response Relationship, Drug; Drinking Behavior; Energy Intake; Fenfluramine; Fluoxetine; Male; Rats; Rats, Sprague-Dawley; Serotonin; Sucrose; Tryptophan

1993
Effect of activation of the serotoninergic system during prolonged starvation on subsequent caloric intake and macronutrient selection in the Zucker rat.
    Appetite, 1993, Volume: 20, Issue:2

    Topics: Animals; Anorexia; Dietary Carbohydrates; Energy Intake; Fenfluramine; Fluoxetine; Food Preferences; Male; Rats; Rats, Zucker; Serotonin; Starvation

1993
Serotonergic agents in the treatment of hypothalamic obesity syndrome: a case report.
    The International journal of eating disorders, 1996, Volume: 20, Issue:1

    Topics: Adult; Body Weight; Brain Damage, Chronic; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Humans; Hyperphagia; Hypothalamic Diseases; Male; Obesity; Selective Serotonin Reuptake Inhibitors; Treatment Failure

1996
Prolactin response to fenfluramine is independent of serotonin release.
    European journal of pharmacology, 1996, Sep-26, Volume: 312, Issue:2

    Topics: Animals; Fenfluramine; Fluoxetine; Male; Prolactin; Rats; Rats, Sprague-Dawley; Serotonin

1996
Serotonergic mediation of fenfluramine discriminative stimuli in fawn-hooded rats.
    Life sciences, 1997, Volume: 60, Issue:6

    Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Ibogaine; Male; Methoxydimethyltryptamines; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Quipazine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents; Serotonin Receptor Agonists

1997
Fluoxetine is a safer alternative to fenfluramine in the medical treatment of obesity.
    Archives of internal medicine, 1997, Jun-09, Volume: 157, Issue:11

    Topics: Appetite Depressants; Fenfluramine; Fluoxetine; Humans; Hypertension, Pulmonary; Obesity; Selective Serotonin Reuptake Inhibitors

1997
Determination of D-fenfluramine, D-norfenfluramine and fluoxetine in plasma, brain tissue and brain microdialysate using high-performance liquid chromatography after precolumn derivatization with dansyl chloride.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, May-09, Volume: 692, Issue:2

    Topics: Animals; Brain; Chromatography, High Pressure Liquid; Dansyl Compounds; Fenfluramine; Fluoxetine; Indicators and Reagents; Microdialysis; Norfenfluramine; Rats; Reference Standards; Selective Serotonin Reuptake Inhibitors

1997
Neuropharmacological effects of low and high doses of repeated oral dexfenfluramine in rats: a comparison with fluoxetine.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 57, Issue:4

    Topics: Administration, Oral; Animals; Appetite Depressants; Body Weight; Brain Chemistry; Catecholamines; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Hippocampus; Indoles; Male; Norfenfluramine; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Stereoisomerism; Time Factors

1997
Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat.
    British journal of pharmacology, 1997, Volume: 121, Issue:8

    Topics: Animals; Cyclobutanes; Cyclohexanols; Eating; Fenfluramine; Fluoxetine; Male; Neurotransmitter Uptake Inhibitors; Obesity; Rats; Rats, Sprague-Dawley; Venlafaxine Hydrochloride

1997
In vivo criteria to differentiate monoamine reuptake inhibitors from releasing agents: sibutramine is a reuptake inhibitor.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cyclobutanes; Fenfluramine; Fluoxetine; Male; Microdialysis; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin

1997
Nutritional implications of xerostomia and rampant caries caused by serotonin reuptake inhibitors: a case study.
    Nutrition reviews, 1997, Volume: 55, Issue:10

    Topics: Adult; Antidepressive Agents; Dental Caries; Diet; Female; Fenfluramine; Fluoxetine; Humans; Obesity; Oral Health; Selective Serotonin Reuptake Inhibitors; Xerostomia

1997
Sensitive measurement of agonist-stimulated [3H]inositol monophosphate accumulation in rat cortical miniprisms.
    Brain research. Brain research protocols, 1997, Volume: 1, Issue:2

    Topics: Animals; Carbachol; Cerebral Cortex; Fenfluramine; Fluoxetine; Histological Techniques; Inositol Phosphates; Male; Monoamine Oxidase Inhibitors; Neurology; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Serotonin; Serotonin Agents; Tranylcypromine; Tritium

1997
p-Chlorophenylalanine and fluoxetine inhibit D-fenfluramine-induced Fos expression in the paraventricular nucleus, cingulate cortex and frontal cortex but not in other forebrain and brainstem regions.
    Brain research, 1997, Nov-07, Volume: 774, Issue:1-2

    Topics: Animals; Appetite Depressants; Brain Stem; Fenclonine; Fenfluramine; Fluoxetine; Frontal Lobe; Gyrus Cinguli; Male; Paraventricular Hypothalamic Nucleus; Prosencephalon; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Agents

1997
Unusual hypotension and bradycardia in a patient receiving fenfluramine, phentermine, and fluoxetine.
    Anesthesiology, 1998, Volume: 88, Issue:2

    Topics: Anesthesia, Conduction; Anesthetics, Intravenous; Appetite Depressants; Bradycardia; Drug Interactions; Fenfluramine; Fentanyl; Fluoxetine; Humans; Hypotension; Intraoperative Complications; Male; Middle Aged; Phentermine; Selective Serotonin Reuptake Inhibitors; Sympathomimetics

1998
Cocaine and selective monoamine uptake blockers (sertraline, nisoxetine, and GBR 12935) prevent the d-fenfluramine-induced head-twitch response in mice.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:1

    Topics: 1-Naphthylamine; Animals; Behavior, Animal; Cocaine; Fenfluramine; Fluoxetine; Male; Mice; Mice, Inbred ICR; Monoamine Oxidase Inhibitors; Piperazines; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Sertraline

1998
Reversal of fenfluramine and fluoxetine anorexia by 8-OH-DPAT is attenuated following raphe injection of 5,7-dihydroxytryptamine.
    Brain research, 1998, Jul-27, Volume: 800, Issue:1

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Brain; Corpus Striatum; Dopamine; Feeding Behavior; Fenfluramine; Fluoxetine; Hippocampus; Hydroxyindoleacetic Acid; Hypothalamus; Infusions, Parenteral; Male; Neurotoxins; Norepinephrine; Piperazines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists

1998
An investigation into the effects of 5-HT agonists and receptor antagonists on ethanol self-administration in the rat.
    Alcohol (Fayetteville, N.Y.), 1998, Volume: 16, Issue:3

    Topics: Animals; Buspirone; Dose-Response Relationship, Drug; Ethanol; Female; Fenfluramine; Fluoxetine; Metergoline; Ondansetron; Piperazines; Rats; Rats, Sprague-Dawley; Ritanserin; Selective Serotonin Reuptake Inhibitors; Self Administration; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors

1998
Functional consequences of central serotonin depletion produced by repeated fenfluramine administration in rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Nov-01, Volume: 18, Issue:21

    Topics: Animals; Behavior, Animal; Body Weight; Brain; Corticosterone; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Male; Prolactin; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Time Factors

1998
The appetite suppressant d-fenfluramine induces apoptosis in human serotonergic cells.
    Neuroreport, 1998, Sep-14, Volume: 9, Issue:13

    Topics: Apoptosis; Appetite Depressants; Biological Transport; Carrier Proteins; Cell Nucleus; Cell Size; Choriocarcinoma; DNA Fragmentation; Dose-Response Relationship, Drug; Female; Fenfluramine; Fluoxetine; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Time Factors; Tumor Cells, Cultured

1998
After fen-phen.
    Newsweek, 1997, Sep-29, Volume: 130, Issue:13

    Topics: Antidepressive Agents, Second-Generation; Appetite Depressants; Consumer Product Safety; Fenfluramine; Fluoxetine; Heart Valve Diseases; Humans; Obesity; Phentermine; Risk Factors; United States; Weight Loss

1997
The promotion effect of anorectic drugs on aflatoxin B(1)-induced hepatic preneoplastic foci.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: Adipose Tissue, Brown; Aflatoxin B1; Amphetamine; Animals; Appetite Depressants; Biomarkers; Body Temperature Regulation; Carcinogens; Chemical and Drug Induced Liver Injury; Cocarcinogenesis; Dopamine; Drug Synergism; Eating; Energy Metabolism; Fenfluramine; Fluoxetine; gamma-Glutamyltransferase; Growth Disorders; Hypothyroidism; Liver Diseases; Liver Neoplasms, Experimental; Male; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344; Selective Serotonin Reuptake Inhibitors; Serotonin; Weight Loss

1999
Regulation of extracellular concentrations of 5-hydroxytryptamine (5-HT) in mouse striatum by 5-HT(1A) and 5-HT(1B) receptors.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:3

    Topics: Animals; Autoreceptors; Corpus Striatum; Fenfluramine; Fluoxetine; Male; Mice; Microdialysis; Oxadiazoles; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Tetrahydronaphthalenes

2000
Serotonin reuptake inhibition does not enhance short term modulation of the exercise ventilatory response.
    Respiration physiology, 2000, Volume: 121, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Female; Fenfluramine; Fluoxetine; Goats; Physical Exertion; Respiratory Dead Space; Respiratory Mechanics; Selective Serotonin Reuptake Inhibitors; Serotonin

2000
Modafinil does not affect serotonin efflux from rat frontal cortex synaptosomes: comparison with known serotonergic drugs.
    Brain research, 2001, Mar-16, Volume: 894, Issue:2

    Topics: Animals; Benzhydryl Compounds; Fenfluramine; Fluoxetine; Frontal Lobe; In Vitro Techniques; Male; Modafinil; Neuroprotective Agents; Paroxetine; Potassium; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sleep; Synaptic Transmission; Synaptosomes; Tritium

2001
LY393558, a 5-hydroxytryptamine reuptake inhibitor and 5-HT(1B/1D) receptor antagonist: effects on extracellular levels of 5-hydroxytryptamine in the guinea pig and rat.
    European journal of pharmacology, 2001, Nov-30, Volume: 432, Issue:1

    Topics: Administration, Oral; Animals; Cyclic S-Oxides; Dose-Response Relationship, Drug; Extracellular Space; Female; Fenfluramine; Fluoxetine; Frontal Lobe; Guinea Pigs; Hypothalamus; Injections, Intraperitoneal; Male; Oxadiazoles; Paroxetine; Piperazines; Rats; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Tetrodotoxin; Thiadiazines; Time Factors

2001
Reduced serotonin release and serotonin uptake sites in the rat nucleus accumbens and striatum after prenatal cocaine exposure.
    Brain research, 2002, Mar-01, Volume: 929, Issue:1

    Topics: Animals; Animals, Newborn; Citalopram; Cocaine; Cocaine-Related Disorders; Electric Stimulation; Female; Fenfluramine; Fetus; Fluoxetine; Methiothepin; Neostriatum; Nucleus Accumbens; p-Chloroamphetamine; Potassium; Pregnancy; Prenatal Exposure Delayed Effects; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents

2002
Overcoming the effects of stress on synaptic plasticity in the intact hippocampus: rapid actions of serotonergic and antidepressant agents.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, May-01, Volume: 22, Issue:9

    Topics: Animals; Antidepressive Agents; Corticosterone; Drug Antagonism; Electrodes, Implanted; Excitatory Postsynaptic Potentials; Exercise Test; Fenfluramine; Fluoxetine; Hippocampus; Long-Term Potentiation; Male; Neuronal Plasticity; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Stress, Physiological; Synapses; Thiazepines

2002
Effects on serotonin in rat hypothalamus of D-fenfluramine, aminorex, phentermine and fluoxetine.
    European journal of pharmacology, 2002, Jun-07, Volume: 445, Issue:1-2

    Topics: Aminorex; Animals; Drug Combinations; Fenfluramine; Fluoxetine; Hypothalamus; Male; Phentermine; Rats; Rats, Sprague-Dawley; Serotonin

2002
Sympathetic activation by fenfluramine depletes brown adipose tissue norepinephrine content in rats.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 73, Issue:3

    Topics: Adipose Tissue; Adipose Tissue, Brown; Adrenal Glands; Animals; Body Temperature; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Male; Myocardium; Nicotinic Antagonists; Norepinephrine; Pentolinium Tartrate; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sympathetic Nervous System

2002
Rat strain differences to fluoxetine in striatal Fos-like proteins.
    Neuroreport, 2002, Dec-20, Volume: 13, Issue:18

    Topics: Animals; Animals, Outbred Strains; Fenfluramine; Fluoxetine; Male; Neostriatum; Proto-Oncogene Proteins c-fos; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Species Specificity

2002
Effects of fluoxetine and d-fenfluramine on cocaine-seeking behavior in rats.
    Psychopharmacology, 2003, Volume: 168, Issue:1-2

    Topics: Animals; Behavior, Addictive; Cocaine; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Rats; Rats, Sprague-Dawley; Reaction Time

2003
Effect of brain serotoninergic stimulation on sodium appetite of euthyroid and hypothyroid rats.
    Experimental physiology, 2003, Volume: 88, Issue:2

    Topics: Animals; Appetite Regulation; Brain; Drinking; Ergolines; Fenfluramine; Fluoxetine; Hypothyroidism; Male; Methimazole; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Sodium Chloride, Dietary

2003
Effects of preexposure to dexfenfluramine, phentermine, dexfenfluramine-phentermine, or fluoxetine on sibutramine-induced hypophagia in the adult rat.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 75, Issue:1

    Topics: Animals; Antidepressive Agents, Second-Generation; Appetite Depressants; Body Weight; Cyclobutanes; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Eating; Fenfluramine; Fluoxetine; Male; Norepinephrine; Phentermine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors

2003
The serotonergic system may be involved in the sleep-inducing action of oleamide in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 368, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Fenfluramine; Fluoxetine; Hypnotics and Sedatives; Male; Neural Pathways; Oleic Acids; Piperazines; Pyridines; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sleep; Sleep, REM; Wakefulness

2003
The effect of the anorectic agent, d-fenfluramine, and its primary metabolite, d-norfenfluramine, on intact human platelet serotonin uptake and efflux.
    Journal of thrombosis and haemostasis : JTH, 2003, Volume: 1, Issue:12

    Topics: Appetite Depressants; Blood Platelets; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Humans; Hydrogen-Ion Concentration; Norfenfluramine; Phentermine; Reserpine; Secretory Vesicles; Selective Serotonin Reuptake Inhibitors; Serotonin

2003
Fenfluramine-induced hypothermia is associated with cutaneous dilation in conscious rats.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 77, Issue:2

    Topics: Animals; Body Temperature; Fenfluramine; Fluoxetine; Hypothermia; Male; Nicotinic Antagonists; Oxygen Consumption; Pentolinium Tartrate; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Selective Serotonin Reuptake Inhibitors; Skin; Tail; Vasodilation

2004
The serotonin transporter (SLC6A4) is present in B-cell clones of diverse malignant origin: probing a potential anti-tumor target for psychotropics.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Burkitt Lymphoma; Cell Line, Tumor; Clomipramine; Fenfluramine; Fluoxetine; Humans; Lymphoma, B-Cell; N-Methyl-3,4-methylenedioxyamphetamine; Proto-Oncogene Proteins c-bcl-2; Psychotropic Drugs; Serotonin Plasma Membrane Transport Proteins

2005
The effect of low estrogen state on serotonin transporter function in mouse hippocampus: a behavioral and electrochemical study.
    Brain research, 2005, Dec-07, Volume: 1064, Issue:1-2

    Topics: Analysis of Variance; Animals; Aromatase; Estrogens; Female; Fenfluramine; Fluoxetine; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Organ Size; Ovariectomy; Reflex, Startle; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Uterus

2005
Comparison of combinations of drugs for treatment of obesity: body weight and echocardiographic status.
    International journal of obesity (2005), 2007, Volume: 31, Issue:5

    Topics: Adult; Appetite Depressants; Body Mass Index; Drug Therapy, Combination; Fenfluramine; Fluoxetine; Heart Valve Diseases; Humans; Medical Records; Obesity; Phentermine; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Ultrasonography; Weight Loss

2007
The synthesis and biological activity of pentafluorosulfanyl analogs of fluoxetine, fenfluramine, and norfenfluramine.
    Bioorganic & medicinal chemistry, 2007, Nov-01, Volume: 15, Issue:21

    Topics: Animals; Fenfluramine; Fluoxetine; Humans; Norfenfluramine; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors

2007
Serotonin (5-HT) transporter ligands affect plasma 5-HT in rats.
    Annals of the New York Academy of Sciences, 2008, Volume: 1139

    Topics: Animals; Fenfluramine; Fluoxetine; Humans; Ligands; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins

2008
Selective serotonin reuptake inhibitors modify physiological gastrointestinal motor activities via 5-HT2c receptor and acyl ghrelin.
    Biological psychiatry, 2009, May-01, Volume: 65, Issue:9

    Topics: Animals; Drugs, Chinese Herbal; Eating; Fenfluramine; Fluoxetine; Fluvoxamine; Gastrointestinal Motility; Ghrelin; Growth Hormone; Injections, Intraventricular; Male; Oligopeptides; Paroxetine; Piperazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Ghrelin; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists

2009
Brain serotonin, psychoactive drugs, and effects on reproduction.
    Central nervous system agents in medicinal chemistry, 2009, Volume: 9, Issue:4

    Topics: Affect; Amphetamine-Related Disorders; Animals; Biological Clocks; Brain; Cognition Disorders; Depressive Disorder; Drug Interactions; Female; Fenfluramine; Fluoxetine; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Obesity; Psychotropic Drugs; Reproduction; Serotonin; Serotonin Receptor Agonists; Sexual Behavior, Animal; Substance-Related Disorders; Synaptic Transmission

2009
Neurobiological changes mediating the effects of chronic fluoxetine on cocaine use.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:8

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Fenfluramine; Fluoxetine; Functional Neuroimaging; Macaca mulatta; Male; Microdialysis; Positron-Emission Tomography; Prolactin; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Self Administration; Serotonin; Serotonin Plasma Membrane Transport Proteins

2012
Acute d-fenfluramine, but not fluoxetine decreases sweet intake in BALB/c, C57BL/6 and SWR inbred mouse strains.
    Physiology & behavior, 2020, 10-01, Volume: 224

    Topics: Animals; Fenfluramine; Fluoxetine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Narcotic Antagonists; Sucrose

2020