fluoxetine and doxepin

fluoxetine has been researched along with doxepin in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19904 (14.29)18.7374
1990's7 (25.00)18.2507
2000's8 (28.57)29.6817
2010's9 (32.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Shafey, H1
Friedman, LM; Marby, DW; Orzack, MH1
Lazarus, A1
Lehtinen, VV; Tamminen, TT1
Fisch, C1
Cohn, JB; Feighner, JP1
Carter, RB; Leander, JD1
Findling, RL; Perel, JM; Wisner, KL1
Baker, B; Dorian, P; Irvine, MJ; Mitchell, J; Sandor, P; Schell, C; Shapiro, C1
Baker, B; Dorian, P; Irvine, J; Khaykin, Y; Mironov, D; Newman, D; Sandor, P; Shapiro, C1
Baker, B; Dorian, P; Irvine, J; McKessok, D; Mendlowitz, S; Sandor, P1
Pan, GZ; Qian, JM; Wang, WA1
Bateman, DN; Chick, J; Good, AM; Kelly, CA; Masterton, G1
Bartels, M; Buchkremer, G; Eschweiler, GW; Klein, R; Köhler, N; Laske, C; Leyhe, T; Richartz, E; Schott, K; Stransky, E; Wittorf, A1
Chen, CC; Gerner, P; Huang, CJ; Hung, YC; Pan, YY; Srinavasan, V; Suzuki, S; Wang, CF1
Davies, H; Fang, M; Hu, X; Hu, Z; Jiang, F; Li, Y; Ling, S; Rudd, JA1
Makuch, W; Mika, J; Przewlocka, B; Rojewska, E; Zychowska, M1
Baik, HJ; Chung, RK; Kim, DY; Lee, GY; Park, HJ; Woo, JH; Zuo, Z1
Jiao, Y; Liang, Y; Lin, J; Qu, H; Sun, Y; Xu, J; Zhao, C1

Reviews

2 review(s) available for fluoxetine and doxepin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antidepressant treatment during breast-feeding.
    The American journal of psychiatry, 1996, Volume: 153, Issue:9

    Topics: Age Factors; Antidepressive Agents; Antidepressive Agents, Tricyclic; Breast Feeding; Depression, Postpartum; Doxepin; Female; Fluoxetine; Humans; Infant; Infant, Newborn; Lactation; Milk, Human; Pregnancy; Risk Assessment

1996

Trials

6 trial(s) available for fluoxetine and doxepin

ArticleYear
Weight changes on fluoxetine as a function of baseline weight in depressed outpatients.
    Psychopharmacology bulletin, 1990, Volume: 26, Issue:3

    Topics: Adult; Aged; Body Weight; Depression; Double-Blind Method; Doxepin; Female; Fluoxetine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Time Factors

1990
A double-blind parallel study to compare fluoxetine with doxepin in the treatment of major depressive disorders.
    International clinical psychopharmacology, 1989, Volume: 4 Suppl 1

    Topics: Adult; Depressive Disorder; Double-Blind Method; Doxepin; Female; Fluoxetine; Humans; Male; Middle Aged; Random Allocation

1989
Double-blind comparative trials of fluoxetine and doxepin in geriatric patients with major depressive disorder.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:3 Pt 2

    Topics: Age Factors; Aged; Anxiety; Blood Pressure; Body Weight; Clinical Trials as Topic; Depressive Disorder; Dizziness; Double-Blind Method; Doxepin; Female; Fluoxetine; Headache; Heart Rate; Humans; Male; Middle Aged; Nausea; Propylamines; Psychiatric Status Rating Scales; Sleep Stages; Xerostomia

1985
Electrocardiographic effects of fluoxetine and doxepin in patients with major depressive disorder.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Doxepin; Electrocardiography; Female; Fluoxetine; Heart Conduction System; Humans; Long QT Syndrome; Male; Middle Aged; Personality Inventory; Signal Processing, Computer-Assisted

1997
Autonomic correlates of antidepressant treatment using heart-rate variability analysis.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1998, Volume: 43, Issue:2

    Topics: Analysis of Variance; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Autonomic Nervous System; Depressive Disorder; Double-Blind Method; Doxepin; Fluoxetine; Heart Rate; Humans; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

1998
Effectiveness of fluoxetine and doxepin in treatment of melancholia in depressed patients.
    Depression and anxiety, 1998, Volume: 7, Issue:2

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Doxepin; Female; Fluoxetine; Humans; Male; Middle Aged; Personality Inventory; Treatment Outcome

1998

Other Studies

20 other study(ies) available for fluoxetine and doxepin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations

2002
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The effect of fluoxetine in depression associated with multiple sclerosis.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1992, Volume: 37, Issue:2

    Topics: Adult; Cognition Disorders; Depressive Disorder; Doxepin; Female; Fluoxetine; Humans; Multiple Sclerosis

1992
Rhabdomyolysis in a depressed patient following overdose with combined drug therapy and alcohol.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:2

    Topics: Adult; Alcoholic Intoxication; Depressive Disorder; Diazepam; Doxepin; Fluoxetine; Humans; Male; Rhabdomyolysis

1990
Effect of fluoxetine on the electrocardiogram.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:3 Pt 2

    Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Bundle-Branch Block; Doxepin; Electrocardiography; Female; Fluoxetine; Heart; Heart Conduction System; Heart Rate; Humans; Imipramine; Male; Middle Aged; Propylamines; Retrospective Studies

1985
Effects of norepinephrine and serotonin uptake inhibitors on the schedule-controlled behavior of the pigeon.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 20, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Columbidae; Conditioning, Operant; Desipramine; Doxepin; Fluoxetine; Iprindole; Male; Norepinephrine; Protriptyline; Reinforcement Schedule; Serotonin Antagonists

1984
[Treatment of refractory irritable bowel syndrome with subclinical dosage of antidepressants].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2003, Volume: 25, Issue:1

    Topics: Adult; Antidepressive Agents; Doxepin; Female; Fluoxetine; Follow-Up Studies; Humans; Irritable Bowel Syndrome; Male; Middle Aged; Paroxetine; Quality of Life

2003
Are selective serotonin re-uptake inhibitors associated with an increased risk of self-harm by antidepressant overdose?
    European journal of clinical pharmacology, 2004, Volume: 60, Issue:3

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Doxepin; Drug Overdose; Drug Prescriptions; Emergency Service, Hospital; Female; Fluoxetine; Humans; Imipramine; Information Services; Male; Mianserin; Mirtazapine; Paroxetine; Patient Admission; Patient Readmission; Poison Control Centers; Retrospective Studies; Risk Assessment; Scotland; Selective Serotonin Reuptake Inhibitors; Self-Injurious Behavior; Sertraline; Trazodone; Venlafaxine Hydrochloride

2004
Increased BDNF serum concentration in fibromyalgia with or without depression or antidepressants.
    Journal of psychiatric research, 2007, Volume: 41, Issue:7

    Topics: Amitriptyline; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Depressive Disorder, Major; Dose-Response Relationship, Drug; Doxepin; Female; Fibromyalgia; Fluoxetine; Humans; Male; Middle Aged; Neuronal Plasticity; Nociceptors; Pain Threshold; Reference Values; Spinal Cord

2007
Resiniferatoxin combined with antidepressants preferentially prolongs sensory/nociceptive block in rat sciatic nerve.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Behavior, Animal; Diterpenes; Doxepin; Drug Synergism; Fluoxetine; Male; Nerve Block; Nociceptors; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sensory Receptor Cells

2010
The alteration of 5-HT(2A) and 5-HT(2C) receptors is involved in neuronal apoptosis of goldfish cerebellum following traumatic experience.
    Neurochemistry international, 2012, Volume: 61, Issue:2

    Topics: Analysis of Variance; Animal Fins; Animals; Antidepressive Agents, Tricyclic; Apoptosis; bcl-Associated Death Protein; Behavior, Animal; Blotting, Western; Brain Injuries; Cerebellum; Doxepin; Fluoxetine; Goldfish; Immunohistochemistry; In Situ Nick-End Labeling; Neurons; Proto-Oncogene Proteins c-fos; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Selective Serotonin Reuptake Inhibitors; Stress Disorders, Post-Traumatic

2012
The influence of microglia activation on the efficacy of amitriptyline, doxepin, milnacipran, venlafaxine and fluoxetine in a rat model of neuropathic pain.
    European journal of pharmacology, 2015, Feb-15, Volume: 749

    Topics: Amitriptyline; Animals; Antidepressive Agents; Calcium-Binding Proteins; Cyclohexanols; Cyclopropanes; Doxepin; Fluoxetine; Ganglia, Spinal; Hyperalgesia; Male; Microfilament Proteins; Microglia; Milnacipran; Neuralgia; Rats, Wistar; Sciatic Nerve; Spinal Cord; Treatment Outcome; Venlafaxine Hydrochloride

2015
Doxepin and imipramine but not fluoxetine reduce the activity of the rat glutamate transporter EAAT3 expressed in Xenopus oocytes.
    BMC anesthesiology, 2015, Aug-08, Volume: 15

    Topics: Animals; Antidepressive Agents; Dose-Response Relationship, Drug; Doxepin; Excitatory Amino Acid Transporter 3; Female; Fluoxetine; Glutamic Acid; Imipramine; Oocytes; Protein Kinase C; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Xenopus laevis

2015
Comparative efficacy and acceptability of antidepressant treatment in poststroke depression: a multiple-treatments meta-analysis.
    BMJ open, 2017, Aug-03, Volume: 7, Issue:8

    Topics: Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Depression; Depressive Disorder; Doxepin; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Morpholines; Paroxetine; Patient Acceptance of Health Care; Reboxetine; Selective Serotonin Reuptake Inhibitors; Stroke; Treatment Outcome

2017