fluoxetine and donepezil

fluoxetine has been researched along with donepezil in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (20.00)29.6817
2010's15 (75.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Bolognesi, ML; Cavalli, A; Melchiorre, C; Minarini, A; Recanatini, M; Rosini, M; Tumiatti, V1
Lv, W; Xue, Y1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Sen, S; Sinha, N1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Qin, W; Tian, S; Wold, EA; Xu, Q; Ye, N; Zhen, XC; Zhou, J1
Garrido Barral, A; González Moneo, MJ1
de Boissezon, X; de Boysson, C; Démonet, JF; Peran, P1
Fritz, K; Marshall, K; Thom, W; Xiong, GL1
Chew, AP; Lim, WS; Tan, KT1
Chae, YJ; Choi, JS; Hahn, SJ; Jeon, JH; Kim, IB; Lee, HJ; Sung, KW1
Gore, C; Wu, C1

Reviews

6 review(s) available for fluoxetine and donepezil

ArticleYear
Multi-target-directed ligands to combat neurodegenerative diseases.
    Journal of medicinal chemistry, 2008, Feb-14, Volume: 51, Issue:3

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Binding Sites; Calcium Channel Blockers; Chelating Agents; Cholinesterase Inhibitors; Humans; Huntington Disease; Ligands; Multiple Sclerosis; Neurodegenerative Diseases; Neurofibrillary Tangles; Neurotransmitter Agents; Parkinson Disease; Plaque, Amyloid

2008
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases.
    Journal of medicinal chemistry, 2020, 12-24, Volume: 63, Issue:24

    Topics: Allosteric Regulation; Clinical Trials as Topic; Humans; Ligands; Nervous System Diseases; Piperidines; Receptors, sigma; Sigma-1 Receptor; Small Molecule Libraries

2020
[Latest therapies for treating dementia].
    Atencion primaria, 2002, May-15, Volume: 29, Issue:8

    Topics: Adult; Aged; Alzheimer Disease; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clinical Trials as Topic; Cognition; Cohort Studies; Controlled Clinical Trials as Topic; Dementia, Vascular; Donepezil; Female; Fluoxetine; Galantamine; Haloperidol; Hormone Replacement Therapy; Humans; Hydroxychloroquine; Indans; Middle Aged; Nootropic Agents; Piperidines; Placebos; Practice Guidelines as Topic; Quality of Life; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Time Factors; Trazodone

2002
Pharmacotherapy of aphasia: myth or reality?
    Brain and language, 2007, Volume: 102, Issue:1

    Topics: Amphetamine; Aphasia; Bromocriptine; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Dopamine Agents; Fluoxetine; GABA Agonists; Humans; Indans; Neuroprotective Agents; Paroxetine; Physostigmine; Piperidines; Piracetam; Pyridines; Selective Serotonin Reuptake Inhibitors; Serotonin; Stroke; Zolpidem

2007
Medical Therapies of Amblyopia: Translational Research to Expand Our Treatment Armamentarium.
    Seminars in ophthalmology, 2016, Volume: 31, Issue:1-2

    Topics: Amblyopia; Carbidopa; Cholinesterase Inhibitors; Donepezil; Dopamine Agonists; Drug Combinations; Fluoxetine; Humans; Indans; Levodopa; Neuronal Plasticity; Piperidines; Selective Serotonin Reuptake Inhibitors; Translational Research, Biomedical; Visual Cortex

2016

Other Studies

14 other study(ies) available for fluoxetine and donepezil

ArticleYear
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Prediction of acetylcholinesterase inhibitors and characterization of correlative molecular descriptors by machine learning methods.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Algorithms; Artificial Intelligence; Cholinesterase Inhibitors; Computational Biology; Drug Design; Models, Chemical; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Toxic interaction between fluoxetine and donepezil: a case of cholinergic toxidrome.
    The Journal of neuropsychiatry and clinical neurosciences, 2012,Spring, Volume: 24, Issue:2

    Topics: Aged; Antidepressive Agents, Second-Generation; Cholinesterase Inhibitors; Donepezil; Drug Interactions; Fluoxetine; Humans; Indans; Male; Piperidines

2012
Donepezil-induced hepatotoxicity in an elderly adult taking fluoxetine.
    Journal of the American Geriatrics Society, 2014, Volume: 62, Issue:10

    Topics: Aged; Alanine Transaminase; Alzheimer Disease; Antidepressive Agents, Second-Generation; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cholinesterase Inhibitors; Donepezil; Fluoxetine; Humans; Indans; Male; Piperidines

2014
Effects of donepezil on hERG potassium channels.
    Brain research, 2015, Feb-09, Volume: 1597

    Topics: Blotting, Western; Cell Membrane; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoxetine; HEK293 Cells; Humans; Indans; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Piperidines; Selective Serotonin Reuptake Inhibitors

2015