fluoxetine has been researched along with diazepam in 104 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (4.81) | 18.7374 |
| 1990's | 6 (5.77) | 18.2507 |
| 2000's | 36 (34.62) | 29.6817 |
| 2010's | 50 (48.08) | 24.3611 |
| 2020's | 7 (6.73) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Both, FL; Elisabetsky, E; Henriques, AT; Kerber, VA; Meneghini, L | 1 |
| Caron, G; Ermondi, G | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
| Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ | 1 |
| Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Bagal, SK; Brown, AD; Cox, PJ; Omoto, K; Owen, RM; Pryde, DC; Sidders, B; Skerratt, SE; Stevens, EB; Storer, RI; Swain, NA | 1 |
| Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Beaumont, K; Di, L; Maurer, TS; Smith, DA | 1 |
| Cho, H; Elkamhawy, A; Heo, JC; Kim, HY; Kim, KH; Lee, CO; Nam, DH; Pae, AN; Park, WK; Roh, EJ; Seol, HJ; Viswanath, AN; Yang, H | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Lazarus, A | 1 |
| Nicholson, AN; Pascoe, PA; Turner, C | 1 |
| Bergstrom, RF; Bosomworth, JC; Lemberger, L; Rowe, H; Tenbarge, JB | 1 |
| Burns, M; Moskowitz, H | 1 |
| Aronoff, GR; Bergstrom, RF; Enas, GG; Farid, NA; Lemberger, L; Wolen, RL | 1 |
| Grandison, L | 1 |
| Corbett, R; Cornfeldt, M; Dunn, RW; Smith, C; Szewczak, M; Woods, A | 1 |
| Da-Rocha, MA; Puech, AJ; Thiébot, MH | 1 |
| Matthews, J; Pollack, MH; Scott, EL | 1 |
| Bustos, SG; Lacerra, C; Martijena, ID; Molina, VA | 1 |
| Bhattacharya, SK; Jaiswal, AK; Singh, M; Singh, Y | 1 |
| Carlson, EC; de Felipe, C; Harrison, T; Hunt, S; Oates, B; Owen, S; Rupniak, NM; Seward, E; Wheeldon, A | 1 |
| Dodman, NH | 1 |
| Ballard, TM; Higgins, GA; Sänger, S | 1 |
| Avisar, A; Joel, D | 1 |
| Barreau, S; Belzung, C; Calatayud, F; Le Guisquet, AM | 1 |
| Belzung, C; El Hage, W; Griebel, G; Moindrot, N | 1 |
| Cecil, A; Crites, G; Goldenberg, R; Knapp, RJ; Malatynska, E; Miller, C; Shuck, C; Watkins, J | 1 |
| Chrousos, GP; Gabry, KE; Gold, PW; McCann, SM; Mostafa, RM; Negrao, AB; Rice, KC; Sternberg, E; Webster, EL | 1 |
| Stone, A | 1 |
| Diaz, A; Fouilloux, C; Ortiz, S | 1 |
| Kamei, J; Miyata, S; Morita, K; Saitoh, A; Takeda, H | 1 |
| Belzung, C; El Hage, W; Griebel, G; Peronny, S | 1 |
| Borelli, KG; Brandão, ML; Coimbra, NC; Nobre, MJ | 1 |
| Bertotto, ME; Bustos, SG; Martijena, ID; Molina, VA | 1 |
| Griebel, G; Scatton, B; Stemmelin, J | 1 |
| Biba, A; Christodoulou, A; Chrysikakou, S; Giannou, H; Kontis, D; Maillis, A; Pallidi, S; Rabavilas, A; Tsaltas, E | 1 |
| Bosse, GM; Compton, R; Spiller, HA | 1 |
| Cohen, C; Depoortère, R; Griebel, G; Louis, C | 1 |
| Barsvári, B; Haller, J; Levay, G; Leveleki, C; Mikics, E; Soproni, K; Sziray, N | 1 |
| Juvonen, R; Korhonen, LE; Pelkonen, O; Raunio, H; Tolonen, A; Turpeinen, M; Uusitalo, J | 1 |
| Kolb, Y; Nicolas, LB; Prinssen, EP | 1 |
| Crabbe, JC; Kliethermes, CL | 1 |
| Alonso, R; Avenet, P; Bergis, O; Cohen, C; Decobert, M; Françon, D; Griebel, G; Keane, P; le Fur, G; Lopez-Grancha, M; Pichat, P; Santucci, V; Scatton, B; Stahl, SM; Stemmelin, J; Terranova, JP | 1 |
| Baroncelli, L; Castrén, E; De Pasquale, R; Maffei, L; Maya Vetencourt, JF; O'Leary, OF; Sale, A; Viegi, A | 1 |
| Bespalov, AY; Gross, G; Mezler, M; Schoemaker, H; Sukhotina, IA; van Gaalen, MM; Wicke, K | 1 |
| Lin, Y; Quartermain, D; Stone, EA | 1 |
| Castrén, E; Wu, X | 1 |
| Georgievskava, Z; Georgievsky, I; Marshall, KP | 1 |
| Henes, K; Mauch, CP; Micale, V; Pamplona, FA; Takahashi, RN; Wotjak, CT | 1 |
| Birkett, MA; Kessler, EJ; Meyer, JS; Ritchie, S; Rowlett, JK; Shinday, NM | 1 |
| Herzberg, D | 1 |
| Colwill, RM; Creton, R; Pelkowski, SD; Richendrfer, H | 1 |
| Baier, H; Ingraham, HA; Meijsing, SH; Muto, A; Schaaf, MJ; Schoonheim, PJ; Strasser, D; Yamamoto, KR; Ziv, L | 1 |
| Charoenphandhu, J; Charoenphandhu, N; Krishnamra, N; Lapmanee, S; Teerapornpuntakit, J | 1 |
| Coleman, HM; Khan, SJ; Le-Clech, P; Stuetz, RM; Trinh, T; van den Akker, B | 1 |
| Calo, G; Guerrini, R; Pulga, A; Rizzi, A; Ruzza, C | 1 |
| Clark, JA; Klee, N; Nizami, M; Platt, B; Schulenberg, J | 1 |
| Amaral, VC; Campos, KF; Miguel, TT; Nunes-de-Souza, RL; Rico, JL | 1 |
| Anderson, MH; Munafò, MR; Robinson, ES | 1 |
| Mendes-Gomes, J; Nunes-de-Souza, RL; Rico, JL; Rodgers, RJ; Sorregotti, T | 1 |
| Connor, B; Evans, J; Kydd, R; Russell, B; Sun, Y | 1 |
| David, DJ; Ebert, B; Gardier, AM; Guiard, BP; Guilloux, JP; Hen, R; Mendez-David, I; Miller, S; Orvoën, S; Pehrson, A; Repérant, C; Sanchez, C | 1 |
| Conkle, JL; Ernst, F; Gan, J; Wu, X | 1 |
| Al-Monajjed, R; Ciarimboli, G; Dobrivojevic, M; Edemir, B; Harrach, S; Holle, SK; Klassen, P; Massmann, V; Pavenstädt, H; Schlatter, E; Sindic, A | 1 |
| Fan, Y; Li, M; Li, S; Ma, Y; Ren, Y; Sawmiller, D; Tan, J; Wang, C | 1 |
| Atayee, RS; Best, BM; Luk, S; Ma, JD | 1 |
| Costa, EA; Da Rocha, FF; Fajemiroye, JO; Florentino, IF; Galdino, PM; Ghedini, PC; Polepally, PR; Zjawiony, JK | 1 |
| Avcikurt, AS; Kockar, F; Sinan, S | 1 |
| Abreu, MS; Barcellos, LJ; Ferreira, D; Giacomini, AC; Gusso, D; Koakoski, G; Oliveira, TA; Piato, AL; Rosa, JG | 1 |
| Endres, M; Gertz, K; Hellmann-Regen, J; Heuser, I; Kronenberg, G; Otte, C; Regen, F; Uhlemann, R | 1 |
| Almeida-Souza, TH; Goes, TC; Teixeira-Silva, F | 1 |
| Chen, H; Chen, W; Li, M; Qin, J; Sui, N; Yang, Y | 1 |
| Abreu, MS; Barcellos, LJG; Bonan, CD; Giacomini, ACVV; Giacomini, LV; Mocelin, R; Piato, AL; Rambo, CL; Siebel, AM; Zimerman, FF | 1 |
| Eder, M; Hladky, F; Holsboer, F; Schmidt, MV; Stepan, J; Uribe, A | 1 |
| Barcellos, HH; Barcellos, LJ; de Abreu, MS; de Oliveira, TA; Fagundes, M; Giacomini, AC; Gusso, D; Idalencio, R; Kalichak, F; Koakoski, G; Piato, AL; Rosa, JG | 1 |
| André, E; de Sousa Pinto, ÍA; Gavioli, EC; Lovick, T; Santos, RO; Soares-Rachetti, Vde P | 1 |
| Furuya, Y; Ino, M; Shibata, H; Shikata, K; Shin, K; Taguchi, R | 1 |
| Abreu, MS; Barcellos, LJ; Friedrich, MT; Giacomini, AC; Gusso, D; Koakoski, G; Piato, AL; Saibt, N; Zanandrea, R | 1 |
| Orlando, JM | 1 |
| Abbasi, MM; Ghorbanihaghjo, A; Kosari-Nasab, M; Salari, AA; Shokouhi, G | 1 |
| Chen, F; Chen, L; Gu, L; Lin, Z; Ouyang, L; Zhang, Q; Zhao, Y | 1 |
| Barbacci, DC; Bonci, A; Jackson, SN; Woods, AS | 1 |
| Garg, C; Garg, M; Walia, V | 1 |
| Bullich, S; Déglon, N; Delcourte, S; Guiard, BP; Haddjeri, N; Lejards, C; Malnou, CE; Portal, B; Rovera, R | 1 |
| Brito, ES; Campos, AR; Costa, AM; Dionisio, AP; Holanda, DKR; Iunes, MF; Moreira, RA; Ribeiro, PRV; Sousa, PHM; Wurlitzer, NJ | 1 |
| Lino-de-Oliveira, C; Pagani, MR; Ramirez, MF; Ramos-Hryb, AB | 1 |
| Ali, SM; Anwer, L; Khaliq, SA; Shamim, S; Younus, I | 1 |
| Esmaili, A; Farmanesh, E; Fereidoni, M; Moghimi, A; Rahati Quchani, M; Rahati Quchani, S | 1 |
| Graham, BM; Pestana, JE | 1 |
| Barbui, C; Bighelli, I; Caldwell, DM; Cipriani, A; Davies, SJ; Dawson, S; Dias, S; Furukawa, TA; Guaiana, G; Imai, H; Koesters, M; Meader, N; Pompoli, A; Robertson, L; Tajika, A | 1 |
4 review(s) available for fluoxetine and diazepam
| Article | Year |
|---|---|
Ion channels as therapeutic targets: a drug discovery perspective.
Topics: Drug Discovery; Humans; Ion Channels; Models, Molecular; Phylogeny | 2013 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Social reactions to Valium and Prozac: a cultural lag perspective of drug diffusion and adoption.
Topics: Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Chlordiazepoxide; Culture; Diazepam; Drug Industry; Fluoxetine; History, 20th Century; History, 21st Century; Humans; Marketing; Public Opinion; Social Environment | 2009 |
Pharmacological treatments in panic disorder in adults: a network meta-analysis.
Topics: Adult; Alprazolam; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzodiazepines; Clomipramine; Clonazepam; Desipramine; Diazepam; Fluoxetine; Humans; Network Meta-Analysis; Panic Disorder; Paroxetine; Reboxetine; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Venlafaxine Hydrochloride | 2023 |
2 trial(s) available for fluoxetine and diazepam
| Article | Year |
|---|---|
The effects on performance of two antidepressants, alone and in combination with diazepam.
Topics: Adult; Amitriptyline; Attention; Diazepam; Drug Interactions; Fluoxetine; Humans; Male; Memory; Psychological Tests; Reference Values | 1988 |
Open trial study of a combined antidepressant (amitryptiline, perphenazine, diazepam) versus fluoxetine or imipramine in ambulatory depressed patients.
Topics: Adolescent; Adult; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Depressive Disorder; Diazepam; Drug Combinations; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Perphenazine; Prospective Studies; Psychiatric Status Rating Scales | 2002 |
98 other study(ies) available for fluoxetine and diazepam
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Psychopharmacological profile of the alkaloid psychollatine as a 5HT2A/C serotonin modulator.
Topics: Anti-Anxiety Agents; Brazil; Diazepam; Glycosides; Indole Alkaloids; Memory; Models, Biological; Molecular Structure; Monoterpenes; Plants, Medicinal; Psychopharmacology; Psychotria; Receptors, GABA-A; Receptors, Serotonin; Serotonin Receptor Agonists | 2005 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats | 2007 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results | 2011 |
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Volume of Distribution in Drug Design.
Topics: Drug Design; Half-Life; Pharmacokinetics | 2015 |
Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM).
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Dose-Response Relationship, Drug; Drug Discovery; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Models, Molecular; Molecular Conformation; Quinazolines; Structure-Activity Relationship; Temozolomide; Urea | 2015 |
Rhabdomyolysis in a depressed patient following overdose with combined drug therapy and alcohol.
Topics: Adult; Alcoholic Intoxication; Depressive Disorder; Diazepam; Doxepin; Fluoxetine; Humans; Male; Rhabdomyolysis | 1990 |
Modulation of sleep by trimipramine in man.
Topics: Adult; Diazepam; Dibenzazepines; Fluoxetine; Humans; Male; Reaction Time; Sleep; Sleep Stages; Sleep, REM; Trimipramine | 1989 |
The effect of fluoxetine on the pharmacokinetics and psychomotor responses of diazepam.
Topics: Adult; Diazepam; Drug Interactions; Fluoxetine; Humans; Male; Middle Aged; Nordazepam; Propylamines; Psychomotor Performance | 1988 |
Fluoxetine: clinical pharmacology and physiologic disposition.
Topics: Administration, Oral; Adult; Age Factors; Aged; Animals; Antidepressive Agents; Blood Platelets; Blood Proteins; Carbon Radioisotopes; Chlorothiazide; Diazepam; Fasting; Fluoxetine; Half-Life; Humans; Intestinal Absorption; Kinetics; Propylamines; Rats; Renal Dialysis; Serotonin; Tolbutamide | 1985 |
Suppression of prolactin secretion by benzodiazepines in vivo.
Topics: 5-Hydroxytryptophan; Animals; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Female; Fluoxetine; Haloperidol; Male; Pregnancy; Proestrus; Prolactin; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Physiological | 1982 |
Selective serotonin re-uptake inhibitors decrease schedule-induced polydipsia in rats: a potential model for obsessive compulsive disorder.
Topics: Animals; Clomipramine; Conditioning, Operant; Desipramine; Diazepam; Disease Models, Animal; Drinking Behavior; Fluoxetine; Haloperidol; Male; Obsessive-Compulsive Disorder; Rats; Rats, Wistar; Reinforcement Schedule; Selective Serotonin Reuptake Inhibitors | 1993 |
Influence of anxiolytic drugs on the effects of specific serotonin reuptake inhibitors in the forced swimming test in mice.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Diazepam; Drug Interactions; Flumazenil; Fluoxetine; GABA Modulators; Male; Mice; Motor Activity; Selective Serotonin Reuptake Inhibitors | 1997 |
Gabapentin as a potential treatment for anxiety disorders.
Topics: Acetates; Adult; Alprazolam; Amines; Anticonvulsants; Anxiety Disorders; Cyclohexanecarboxylic Acids; Diazepam; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Panic Disorder; Phobic Disorders | 1998 |
Benzodiazepine withdrawal facilitates the subsequent onset of escape failures and anhedonia: influence of different antidepressant drugs.
Topics: Amphetamine; Animals; Anti-Anxiety Agents; Antidepressive Agents; Avoidance Learning; Conditioning, Classical; Cues; Desipramine; Diazepam; Electroshock; Escape Reaction; Fluoxetine; Male; Odorants; Phenelzine; Rats; Sexual Behavior, Animal; Substance Withdrawal Syndrome; Time Factors | 1999 |
Effect of prenatal diazepam, phenobarbital, haloperidol and fluoxetine exposure on foot shock induced aggression in rats.
Topics: Aggression; Animals; Diazepam; Drug Evaluation, Preclinical; Electroshock; Female; Fluoxetine; Haloperidol; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Psychotropic Drugs; Rats | 1998 |
Pharmacological blockade or genetic deletion of substance P (NK(1)) receptors attenuates neonatal vocalisation in guinea-pigs and mice.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Buspirone; Diazepam; Dose-Response Relationship, Drug; Female; Fluoxetine; Gene Deletion; Guinea Pigs; Imipramine; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Motor Activity; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Social Isolation; Stress, Psychological; Substance P; Tetrazoles; Vocalization, Animal | 2000 |
Animal behavior case of the month. Roomate rivalry.
Topics: Agonistic Behavior; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Behavior Therapy; Behavior, Animal; Diazepam; Dogs; Female; Fluoxetine; Humans; Male; Social Dominance | 2000 |
Inhibition of shock-induced foot tapping behaviour in the gerbil by a tachykinin NK1 receptor antagonist.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Aprepitant; Conditioning, Operant; Diazepam; Female; Fluoxetine; Gerbillinae; Humans; Male; Morpholines; Motor Activity; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1 | 2001 |
Excessive lever pressing following post-training signal attenuation in rats: a possible animal model of obsessive compulsive disorder?
Topics: Animals; Behavior, Animal; Conditioning, Operant; Cues; Diazepam; Disease Models, Animal; Fluoxetine; GABA Modulators; Handling, Psychological; Injections, Intraperitoneal; Male; Obsessive-Compulsive Disorder; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors | 2001 |
An investigation of the mechanisms responsible for acute fluoxetine-induced anxiogenic-like effects in mice.
Topics: Animals; Anxiety; Arousal; Buspirone; Diazepam; Exploratory Behavior; Fluoxetine; Humans; Male; Mianserin; Mice; Mice, Inbred BALB C; Motor Activity; Quinolines; Receptors, Dopamine; Receptors, Neurotransmitter; Social Environment | 2001 |
Behavioral and neurochemical changes following predatory stress in mice.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Brain Chemistry; Cats; Diazepam; Dopamine; Exploratory Behavior; Fluoxetine; Male; Mice; Mice, Inbred Strains; Norepinephrine; Predatory Behavior; Selective Serotonin Reuptake Inhibitors; Serotonin; Species Specificity; Stress, Psychological | 2001 |
Antidepressant activity of memory-enhancing drugs in the reduction of submissive behavior model.
Topics: Animals; Antidepressive Agents; Competitive Behavior; Desipramine; Diazepam; Dioxoles; Dose-Response Relationship, Drug; Fluoxetine; Injections, Intraperitoneal; Male; Maze Learning; Models, Animal; Nootropic Agents; Piperidines; Piracetam; Pyrrolidinones; Rats; Rats, Sprague-Dawley | 2002 |
Marked suppression of gastric ulcerogenesis and intestinal responses to stress by a novel class of drugs.
Topics: Analysis of Variance; Animals; Bupropion; Buspirone; Colon; Corticotropin-Releasing Hormone; Diazepam; Dose-Response Relationship, Drug; Fluoxetine; Gastric Mucosa; Male; Mucins; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Stomach Ulcer | 2002 |
Chemical weapons. U.S. research on sedatives in combat sets off alarms.
Topics: Behavior; Chemical Warfare; Chemical Warfare Agents; Diazepam; Drug and Narcotic Control; Fluoxetine; Humans; Hypnotics and Sedatives; International Cooperation; Research; Riot Control Agents, Chemical; United States | 2002 |
Effects of selective serotonin reuptake inhibitors on immobility time in the tail suspension test in streptozotocin-induced diabetic mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Anxiety Agents; Blood Glucose; Body Weight; Desipramine; Diabetes Mellitus, Experimental; Diazepam; Dose-Response Relationship, Drug; Fluoxetine; Fluvoxamine; Hindlimb Suspension; Male; Mice; Mice, Inbred ICR; Motor Activity; Selective Serotonin Reuptake Inhibitors | 2003 |
Impaired memory following predatory stress in mice is improved by fluoxetine.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Diazepam; Exploratory Behavior; Fluoxetine; Male; Memory Disorders; Mice; Predatory Behavior; Stress, Psychological | 2004 |
Effects of acute and chronic fluoxetine and diazepam on freezing behavior induced by electrical stimulation of dorsolateral and lateral columns of the periaqueductal gray matter.
Topics: Animals; Diazepam; Disease Models, Animal; Electric Stimulation; Escape Reaction; Fluoxetine; Immobilization; Male; Periaqueductal Gray; Rats; Rats, Wistar | 2004 |
Antidepressants attenuate both the enhanced ethanol intake and ethanol-induced anxiolytic effects in diazepam withdrawn rats.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Central Nervous System Depressants; Choice Behavior; Desipramine; Diazepam; Dose-Response Relationship, Drug; Drinking; Drug Administration Schedule; Drug Interactions; Ethanol; Fluoxetine; Male; Maze Learning; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Time Factors | 2005 |
Effects of the cannabinoid CB1 receptor antagonist rimonabant in models of emotional reactivity in rodents.
Topics: Aggression; Analysis of Variance; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Behavior, Animal; Depression; Diazepam; Dose-Response Relationship, Drug; Electroshock; Emotions; Fluoxetine; Gerbillinae; Immobility Response, Tonic; Male; Maze Learning; Mice; Models, Animal; Neuropsychological Tests; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant | 2005 |
Reinforced spatial alternation as an animal model of obsessive-compulsive disorder (OCD): investigation of 5-HT2C and 5-HT1D receptor involvement in OCD pathophysiology.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Desipramine; Diazepam; Disease Models, Animal; Fluoxetine; Indoles; Male; Maze Learning; Obsessive-Compulsive Disorder; Piperazines; Piperidines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1D; Receptor, Serotonin, 5-HT2C; Reinforcement, Psychology; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Tryptamines | 2005 |
Fatal fluoxetine ingestion with postmortem blood concentrations.
Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Bradycardia; Child, Preschool; Diazepam; Electrocardiography; Epilepsy, Tonic-Clonic; Fatal Outcome; Fluoxetine; GABA Modulators; Heart Arrest; Humans; Male; Midazolam; Obesity; Ventricular Fibrillation | 2005 |
Antidepressant-like effects of the corticotropin-releasing factor 1 receptor antagonist, SSR125543, and the vasopressin 1b receptor antagonist, SSR149415, in a DRL-72 s schedule in the rat.
Topics: Animals; Anti-Anxiety Agents; Antidiuretic Hormone Receptor Antagonists; Behavior, Animal; Conditioning, Operant; Diazepam; Fluoxetine; Hydrocarbons, Halogenated; Indoles; Male; Pyrrolidines; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Reinforcement Schedule; Reinforcement, Psychology; Selective Serotonin Reuptake Inhibitors; Thiazines | 2006 |
Pharmacological evaluation of the stress-induced social avoidance model of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Brain; Buspirone; Chlordiazepoxide; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Fluoxetine; Haloperidol; Male; Models, Neurological; Motor Activity; Phobic Disorders; Piperazines; Rats; Rats, Wistar; Reproducibility of Results; Serotonin Receptor Agonists; Stress, Psychological | 2006 |
Cytochrome P450 (CYP) inhibition screening: comparison of three tests.
Topics: Citalopram; Cytochrome P-450 Enzyme Inhibitors; Diazepam; Enzyme Inhibitors; Fluoxetine; Humans; Oxazepam; Propranolol; Sotalol | 2006 |
A combined marble burying-locomotor activity test in mice: a practical screening test with sensitivity to different classes of anxiolytics and antidepressants.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluoxetine; Haloperidol; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred CBA; Morphine; Motor Activity; Obsessive-Compulsive Disorder; Pyridines; Reproducibility of Results; Species Specificity; Spiro Compounds | 2006 |
Pharmacological and genetic influences on hole-board behaviors in mice.
Topics: Animals; Desipramine; Diazepam; Exploratory Behavior; Female; Fluoxetine; Male; Methamphetamine; Mice; Mice, Inbred Strains; Pentylenetetrazole; Piperazines; Selective Serotonin Reuptake Inhibitors | 2006 |
Stimulation of the beta3-Adrenoceptor as a novel treatment strategy for anxiety and depressive disorders.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Aggression; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety Disorders; Behavior, Animal; Cognition; Depressive Disorder; Diazepam; Ethanol; Exploratory Behavior; Fluoxetine; Gerbillinae; Imipramine; Interpersonal Relations; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, beta-3; Sleep; Substance-Related Disorders; Swimming; Tetrahydronaphthalenes | 2008 |
The antidepressant fluoxetine restores plasticity in the adult visual cortex.
Topics: Amblyopia; Animals; Antidepressive Agents, Second-Generation; Brain-Derived Neurotrophic Factor; Diazepam; Dominance, Ocular; Evoked Potentials, Visual; Fluoxetine; gamma-Aminobutyric Acid; Long-Term Potentiation; Long-Term Synaptic Depression; Neuronal Plasticity; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptic Transmission; Visual Cortex | 2008 |
Behavioral characterization of the mGlu group II/III receptor antagonist, LY-341495, in animal models of anxiety and depression.
Topics: Amino Acids; Amphetamine; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Operant; Darkness; Depression; Diazepam; Fever; Fluoxetine; Light; Male; Mice; Paroxetine; Receptors, Metabotropic Glutamate; Reinforcement Schedule; Stress, Psychological; Xanthenes | 2008 |
Evaluation of the repeated open-space swim model of depression in the mouse.
Topics: Adaptation, Psychological; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Cell Proliferation; Chronic Disease; Depression; Desipramine; Diazepam; Disease Models, Animal; Fluoxetine; Food Preferences; Haloperidol; Hindlimb Suspension; Hypnotics and Sedatives; Male; Mice; Motor Activity; Neurons; Swimming | 2008 |
Co-treatment with diazepam prevents the effects of fluoxetine on the proliferation and survival of hippocampal dentate granule cells.
Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Diazepam; DNA; Drug Combinations; Fluoxetine; GABA Modulators; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neurons; Selective Serotonin Reuptake Inhibitors; Time Factors | 2009 |
Prolonged fear incubation leads to generalized avoidance behavior in mice.
Topics: Animals; Antidepressive Agents, Second-Generation; Avoidance Learning; Behavior, Animal; Conditioning, Classical; Diazepam; Electroshock; Extinction, Psychological; Fear; Fluoxetine; Habituation, Psychophysiologic; Hypnotics and Sedatives; Male; Mice; Mice, Inbred C57BL; Odorants; Time Factors | 2011 |
Acute anxiogenic-like effects of selective serotonin reuptake inhibitors are attenuated by the benzodiazepine diazepam in BALB/c mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Citalopram; Corticosterone; Diazepam; Drug Interactions; Fluoxetine; Male; Mice; Mice, Inbred BALB C; Selective Serotonin Reuptake Inhibitors | 2011 |
Prescribing in an age of "wonder drugs".
Topics: Culture; Diazepam; Drug and Narcotic Control; Drug Discovery; Drug Industry; Drug Prescriptions; Ethics, Pharmacy; Fluoxetine; History, 20th Century; History, 21st Century; Humans; Patient Education as Topic; Psychotropic Drugs | 2011 |
On the edge: pharmacological evidence for anxiety-related behavior in zebrafish larvae.
Topics: Animals; Anxiety; Caffeine; Cues; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluoxetine; Spatial Behavior; Swimming; Zebrafish | 2012 |
An affective disorder in zebrafish with mutation of the glucocorticoid receptor.
Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Anti-Anxiety Agents; Arginine; Brain; Cell Line, Transformed; Chlorocebus aethiops; Corticotropin-Releasing Hormone; Cysteine; Diazepam; Disease Models, Animal; Escape Reaction; Exploratory Behavior; Fluoxetine; Freezing Reaction, Cataleptic; Hormone Antagonists; Humans; Hydrocortisone; Interpersonal Relations; Mifepristone; Mood Disorders; Mutation; Psychomotor Agitation; Radioimmunoassay; Receptors, Glucocorticoid; Serotonin; Transfection; Zebrafish | 2013 |
Duodenal calcium transporter mRNA expression in stressed male rats treated with diazepam, fluoxetine, reboxetine, or venlafaxine.
Topics: Animals; Calcium; Calcium Channels; Cyclohexanols; Diazepam; Duodenum; Fluoxetine; Gene Expression Regulation; Ion Transport; Male; Morpholines; Rats; Reboxetine; Restraint, Physical; RNA, Messenger; Venlafaxine Hydrochloride | 2012 |
Removal of trace organic chemical contaminants by a membrane bioreactor.
Topics: Amitriptyline; Bioreactors; Carbamazepine; Diazepam; Diclofenac; Fluoxetine; Gemfibrozil; Omeprazole; Organic Chemicals; Pharmaceutical Preparations; Sulfamethoxazole; Trimethoprim; Waste Disposal, Fluid; Water Pollutants, Chemical | 2012 |
Anxiolytic- and panicolytic-like effects of Neuropeptide S in the mouse elevated T-maze.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety; Diazepam; Dose-Response Relationship, Drug; Fluoxetine; Male; Maze Learning; Mice; Mice, Knockout; Neuropeptides; Panic Disorder; Reaction Time; Receptors, Neuropeptide | 2012 |
A depressive phenotype induced by Bacille Calmette Guérin in 'susceptible' animals: sensitivity to antidepressants.
Topics: Animals; Antidepressive Agents; BCG Vaccine; Chronic Disease; Depression; Desipramine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxetine; Inflammation; Male; Mice; Motor Activity; Phenotype | 2013 |
Ethopharmacological evaluation of the rat exposure test: a prey-predator interaction test.
Topics: Adrenergic alpha-2 Receptor Antagonists; Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents; Caffeine; Central Nervous System Stimulants; Diazepam; Escape Reaction; Factor Analysis, Statistical; Fluoxetine; Food Chain; Imipramine; Male; Mice; Motor Activity; Posture; Predatory Behavior; Rats; Rats, Long-Evans; Time Factors; Yohimbine | 2013 |
Investigating the psychopharmacology of cognitive affective bias in rats using an affective tone discrimination task.
Topics: Affect; Animals; Anti-Anxiety Agents; Antidepressive Agents; Bias; Cognition; Cues; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Drug Administration Schedule; Fluoxetine; Male; Morpholines; Rats; Reboxetine; Reward | 2013 |
Ethopharmacological analysis of the open elevated plus-maze in mice.
Topics: Adrenergic alpha-2 Receptor Antagonists; Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Convulsants; Corticosterone; Diazepam; Factor Analysis, Statistical; Fluoxetine; Male; Maze Learning; Mice; Pentylenetetrazole; Statistics, Nonparametric; Yohimbine | 2013 |
A benzodiazepine impairs the neurogenic and behavioural effects of fluoxetine in a rodent model of chronic stress.
Topics: Animals; Antidepressive Agents; Benzodiazepines; Brain-Derived Neurotrophic Factor; Diazepam; Disease Models, Animal; Exploratory Behavior; Feeding Behavior; Fluoxetine; Hippocampus; Male; Neurogenesis; Phosphopyruvate Hydratase; Rats; Rats, Wistar; Social Isolation; Stress, Psychological; Swimming; Thymidine; Time Factors | 2013 |
Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Dentate Gyrus; Diazepam; Drug Evaluation, Preclinical; Exploratory Behavior; Fluoxetine; Immobility Response, Tonic; Male; Mice; Motor Activity; Neurogenesis; Piperazines; Sulfides; Vortioxetine | 2013 |
Comparative uptake and translocation of pharmaceutical and personal care products (PPCPs) by common vegetables.
Topics: Adsorption; Carbanilides; Diazepam; Fluoxetine; Household Products; Meprobamate; Pharmaceutical Preparations; Plant Leaves; Plant Roots; Primidone; Tissue Distribution; Triclosan; Vegetables; Wastewater; Water Pollutants, Chemical | 2013 |
The organic cation transporter 3 (OCT3) as molecular target of psychotropic drugs: transport characteristics and acute regulation of cloned murine OCT3.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cells, Cultured; Diazepam; Fluoxetine; HEK293 Cells; Histamine; Humans; Ion Transport; Ketamine; Kidney Tubules, Proximal; Male; Mice; Octamer Transcription Factor-3; Organic Cation Transport Proteins; Psychotropic Drugs; Quaternary Ammonium Compounds; Serotonin; Species Specificity | 2014 |
Chronic mild stress-induced changes of risk assessment behaviors in mice are prevented by chronic treatment with fluoxetine but not diazepam.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Chronic Disease; Corticosterone; Diazepam; Fluoxetine; Male; Mice; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Stress, Psychological | 2014 |
Urinary diazepam metabolite distribution in a chronic pain population.
Topics: Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Chronic Pain; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Diazepam; Drug Interactions; Esomeprazole; Female; Fluoxetine; Humans; Male; Methadone; Nordazepam; Oxazepam; Retrospective Studies; Specimen Handling; Temazepam | 2014 |
Plurality of anxiety and depression alteration mechanism by oleanolic acid.
Topics: alpha-Methyltyrosine; Animals; Anti-Anxiety Agents; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Fenclonine; Fluoxetine; Hippocampus; Imipramine; Male; Mice; Monoamine Oxidase; Motor Activity; Oleanolic Acid; Pentylenetetrazole; Piperazines; Pyridines | 2014 |
Antidepressant and antipsychotic drugs differentially affect PON1 enzyme activity.
Topics: Acepromazine; Antidepressive Agents; Antipsychotic Agents; Aryldialkylphosphatase; Diazepam; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Female; Fluoxetine; Haloperidol; Humans; Kinetics; Molecular Structure | 2015 |
Diazepam and fluoxetine decrease the stress response in zebrafish.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Diazepam; Female; Fluoxetine; Male; Stress, Physiological; Water Pollutants, Chemical; Zebrafish | 2014 |
Direct inhibition of retinoic acid catabolism by fluoxetine.
Topics: Animals; Antidepressive Agents, Second-Generation; Benzhydryl Compounds; Cell Line, Tumor; Cell Survival; Cerebral Cortex; Chromatography, High Pressure Liquid; Diazepam; Dose-Response Relationship, Drug; Fluoxetine; Glutamic Acid; Humans; Modafinil; Neurons; Neuroprotective Agents; Rats, Wistar; Receptors, Retinoic Acid; Synaptosomes; Tretinoin | 2015 |
Pharmacological validation of the free-exploratory paradigm in male Wistar rats: A proposed test of trait anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Diazepam; Drug Evaluation, Preclinical; Exploratory Behavior; Fluoxetine; Male; Motor Activity; Pentylenetetrazole; Rats; Rats, Wistar | 2015 |
Behavioral and pharmacological investigation of anxiety and maternal responsiveness of postpartum female rats in a pup elevated plus maze.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Diazepam; Dopamine D2 Receptor Antagonists; Female; Fluoxetine; Haloperidol; Maternal Behavior; Maze Learning; Motivation; Postpartum Period; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors | 2015 |
Fluoxetine and diazepam acutely modulate stress induced-behavior.
Topics: Aggression; Animals; Behavior, Animal; Diazepam; Disease Models, Animal; Female; Fluoxetine; GABA Modulators; Male; Motor Activity; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Zebrafish | 2016 |
High-Speed imaging reveals opposing effects of chronic stress and antidepressants on neuronal activity propagation through the hippocampal trisynaptic circuit.
Topics: Animals; Antidepressive Agents; Azepines; Benzamides; Brain-Derived Neurotrophic Factor; Central Nervous System Agents; Chronic Disease; Diazepam; Disease Models, Animal; Dominance-Subordination; Fluoxetine; Haloperidol; Hippocampus; Ketamine; Lithium Compounds; Male; Mice, Inbred C57BL; Neural Pathways; Stress, Psychological; Tissue Culture Techniques; Voltage-Sensitive Dye Imaging | 2015 |
Waterborne psychoactive drugs impair the initial development of Zebrafish.
Topics: Animals; Diazepam; Embryo, Nonmammalian; Embryonic Development; Female; Fluoxetine; Larva; Male; Mortality; Psychotropic Drugs; Risperidone; Water Pollutants, Chemical; Zebrafish | 2016 |
Short term, low dose fluoxetine blocks estrous cycle-linked changes in responsiveness to diazepam in female rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Brain; Diazepam; Estrous Cycle; Estrus; Female; Fluoxetine; gamma-Aminobutyric Acid; Locomotion; Maze Learning; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Selective Serotonin Reuptake Inhibitors; Serotonin | 2016 |
Selective corticotropin-releasing factor 1 receptor antagonist E2508 has potent antidepressant-like and anxiolytic-like properties in rodent models.
Topics: Acetylcholine; Administration, Oral; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Cyclic AMP; Depressive Disorder, Major; Diazepam; Disease Models, Animal; Female; Fluoxetine; HEK293 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Muscle Strength; Pyrazoles; Pyridines; Pyrimidines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Selective Serotonin Reuptake Inhibitors; Sexual Behavior, Animal | 2016 |
Environmental and Pharmacological Manipulations Blunt the Stress Response of Zebrafish in a Similar Manner.
Topics: Animals; Diazepam; Environmental Exposure; Fluoxetine; Housing, Animal; Hydrocortisone; Stress, Physiological; Zebrafish | 2016 |
Animal Behavior Case of the Month.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Behavior, Animal; Diazepam; Dog Diseases; Dogs; Fear; Fluoxetine; Gabapentin; Male; Noise; Paroxetine; Phobic Disorders | 2017 |
Anxiolytic- and antidepressant-like effects of Silymarin compared to diazepam and fluoxetine in a mouse model of mild traumatic brain injury.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Brain Injuries, Traumatic; Diazepam; Disease Models, Animal; Fluoxetine; Maze Learning; Mice; Silymarin; Tumor Necrosis Factor-alpha | 2018 |
Hippocampal astrocyte atrophy in a mouse depression model induced by corticosterone is reversed by fluoxetine instead of benzodiazepine diazepam.
Topics: Animals; Antidepressive Agents; Astrocytes; Atrophy; Corticosterone; Depressive Disorder; Diazepam; Disease Models, Animal; Fluoxetine; Hippocampus; Male; Mice, Inbred C57BL; Random Allocation | 2018 |
An In Vitro Study of Aromatic Stacking of Drug Molecules.
Topics: Anti-Anxiety Agents; Antidepressive Agents; Antineoplastic Agents, Phytogenic; Binding Sites; Diazepam; Drug Interactions; Fluoxetine; Haloperidol; Humans; Models, Molecular; Paclitaxel; Sertraline; Spectrometry, Mass, Electrospray Ionization | 2019 |
Lithium potentiated, pyridoxine abolished and fluoxetine attenuated the anxiolytic effect of diazepam in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Brain; Diazepam; Fluoxetine; Glutamate Decarboxylase; Lithium; Male; Maze Learning; Mice; Pyridoxine | 2019 |
Genetic and pharmacological inactivation of astroglial connexin 43 differentially influences the acute response of antidepressant and anxiolytic drugs.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Astrocytes; Benzodiazepines; Connexin 43; Diazepam; Fluoxetine; Male; Mice; Mice, Inbred C57BL; Selective Serotonin Reuptake Inhibitors | 2020 |
Garlic passion fruit (Passiflora tenuifila Killip): Assessment of eventual acute toxicity, anxiolytic, sedative, and anticonvulsant effects using in vivo assays.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Anxiety; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Fluoxetine; Fruit; Mice; Motor Activity; Passiflora; Pentylenetetrazole; Plant Extracts; Seizures | 2020 |
Stress-mediated hyperactivity and anhedonia resistant to diazepam and fluoxetine in
Topics: Anhedonia; Animals; Diazepam; Disease Models, Animal; Drosophila; Fluoxetine; Stress, Psychological | 2021 |
Anxiolytic, antidepressant and inhibitory effect on MAO isoenzymes by Bougainvillea glabra flower extract in rats.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Diazepam; Flowers; Fluoxetine; Isoenzymes; Male; Monoamine Oxidase Inhibitors; Motor Activity; Nyctaginaceae; Plant Extracts; Psychomotor Performance; Rats; Rats, Wistar; Swimming | 2021 |
Behavioral and electrophysiological (ECoG) effects of haplophyllum robustum and TRPA1 antagonist in adult male wistar rats.
Topics: Animals; Diazepam; Fluoxetine; Plant Extracts; Rats; Rats, Wistar; Rutaceae; Seizures | 2023 |
Reproductive experience alters the effects of diazepam and fluoxetine on anxiety-like behaviour, fear extinction, and corticosterone levels in female rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Corticosterone; Diazepam; Estradiol; Extinction, Psychological; Fear; Female; Fluoxetine; Humans; Pregnancy; Pregnanolone; Progesterone; Rats | 2023 |