fluoxetine and benztropine

fluoxetine has been researched along with benztropine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.76)18.7374
1990's2 (11.76)18.2507
2000's6 (35.29)29.6817
2010's6 (35.29)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Ang, KK; Arkin, MR; Chen, S; Doyle, PS; Engel, JC; McKerrow, JH1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Marsden, CA; Routledge, C1
Gladfelter, WE; Heym, J1
Rothschild, AJ1
Huszonek, JJ1
Grundt, P; Katz, JL; Kopajtic, TA; Newman, AH1
Amara, SG; Mortensen, OV1
Preskorn, SH1
Desai, A; Fraser, R; Gnegy, ME; Guptaroy, B; Zhang, M1
Duarte, D; Nunes, M; Ricardo, S; Vale, N1

Reviews

1 review(s) available for fluoxetine and benztropine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

16 other study(ies) available for fluoxetine and benztropine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8

    Topics: Animals; Cattle; Cell Line; Cell Line, Tumor; Chagas Disease; Drug Evaluation, Preclinical; Hepatocytes; High-Throughput Screening Assays; Humans; Image Processing, Computer-Assisted; Muscle, Skeletal; Parasitic Sensitivity Tests; Trypanocidal Agents; Trypanosoma cruzi

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Lack of selectivity between the uptake of [3H]adrenaline and [3H]noradrenaline into rat hypothalamic slices.
    Journal of neurochemistry, 1987, Volume: 49, Issue:3

    Topics: Animals; Benztropine; Desipramine; Epinephrine; Fluoxetine; Hypothalamus; Male; Maprotiline; Norepinephrine; Rats; Rats, Inbred Strains; Tissue Distribution

1987
Serotonergic innervation of the lateral hypothalamus: evidence from synaptosomal uptake studies.
    Brain research bulletin, 1982, Volume: 8, Issue:2

    Topics: Absorption; Animals; Benztropine; Desipramine; Female; Fluoxetine; Hypothalamus; Kinetics; Mesencephalon; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes

1982
Delirium: an SSRI-benztropine adverse effect?
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:11

    Topics: Adult; Age Factors; Aged; Benztropine; Delirium; Drug Interactions; Fluoxetine; Humans; Middle Aged; Perphenazine; Schizophrenia; Selective Serotonin Reuptake Inhibitors

1995
Anticholinergic effects in a depressed parkinsonian patient.
    Journal of geriatric psychiatry and neurology, 1995, Volume: 8, Issue:2

    Topics: Aged; Benztropine; Carbidopa; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fluoxetine; Humans; Levodopa; Male; Parkinson Disease; Treatment Outcome

1995
N-8-Substituted benztropinamine analogs as selective dopamine transporter ligands.
    Bioorganic & medicinal chemistry letters, 2005, Dec-15, Volume: 15, Issue:24

    Topics: Amines; Benztropine; Binding Sites; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Muscarinic Antagonists; Parasympatholytics; Pirenzepine

2005
Gain of function mutants reveal sites important for the interaction of the atypical inhibitors benztropine and bupropion with monoamine transporters.
    Journal of neurochemistry, 2006, Volume: 98, Issue:5

    Topics: Alanine; Animals; Benztropine; Binding, Competitive; Biological Transport; Bupropion; Chlorocebus aethiops; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Models, Molecular; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Radioligand Assay; Serine; Transfection; Tritium

2006
Deconstructing a medication regimen.
    Journal of psychiatric practice, 2008, Volume: 14, Issue:2

    Topics: Adolescent; Antimanic Agents; Antipsychotic Agents; Benztropine; Biotransformation; Bipolar Disorder; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Fluoxetine; Humans; Lithium Carbonate; Metabolic Clearance Rate; Ranitidine; Risperidone; Stupor; Valproic Acid

2008
Site-directed mutations near transmembrane domain 1 alter conformation and function of norepinephrine and dopamine transporters.
    Molecular pharmacology, 2011, Volume: 79, Issue:3

    Topics: Amphetamine; Benztropine; Binding Sites; Biotinylation; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Fluoxetine; HEK293 Cells; Humans; Immunoblotting; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Pharmacokinetics; Protein Conformation

2011
Combination of Antimalarial and CNS Drugs with Antineoplastic Agents in MCF-7 Breast and HT-29 Colon Cancer Cells: Biosafety Evaluation and Mechanism of Action.
    Biomolecules, 2022, Oct-16, Volume: 12, Issue:10

    Topics: Adenosine Diphosphate; Antimalarials; Antineoplastic Agents; Artesunate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benztropine; Breast Neoplasms; Cell Line, Tumor; Chloroquine; Colonic Neoplasms; Containment of Biohazards; Doxorubicin; Drug Resistance, Neoplasm; Female; Fluorouracil; Fluoxetine; Fluphenazine; Humans; Ki-67 Antigen; MCF-7 Cells; Michigan; NF-kappa B; Paclitaxel; Poly(ADP-ribose) Polymerase Inhibitors; Ribose; Sertraline; Thioridazine

2022