fluoxetine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

fluoxetine has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's3 (33.33)18.2507
2000's1 (11.11)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brooks, WJ; Jarvis, MF; Wagner, GC2
Cohen, O; Globus, M; Melamed, E; Rosenthal, J; Uzzan, A1
Andrews, AM; Murphy, DL2
Ackland, MJ; Alex, AA; de Groot, MJ; Horne, VA; Jones, BC1
He, XJ; Nakayama, H; Shibui, Y; Uchida, K1
Bok, E; Chung, ES; Chung, YC; Jin, BK; Jin, M; Kim, SR; Kim, YS; Ko, HW; Park, ES; Park, JY; Park, KW; Won, SY; Yoon, SH1
Chung, YC; Jin, BK; Kim, KI1

Other Studies

9 other study(ies) available for fluoxetine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

ArticleYear
Astrocytes as a primary locus for the conversion MPTP into MPP+.
    Journal of neural transmission, 1989, Volume: 76, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Astrocytes; Biotransformation; Corpus Striatum; Dopamine; Fluoxetine; Male; Mice; Monoamine Oxidase; Neurotoxins; Pyridines; Pyridinium Compounds; Reference Values; Serotonin

1989
Attenuation of MPTP-induced dopaminergic neurotoxicity by a serotonin uptake blocker.
    Journal of neural transmission, 1988, Volume: 71, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Corpus Striatum; Dopamine; Fluoxetine; Male; Neurotoxins; Propylamines; Pyridines; Rats; Rats, Inbred Strains; Serotonin

1988
Dopamine but not norepinephrine or serotonin uptake inhibitors protect mice against neurotoxicity of MPTP.
    European journal of pharmacology, 1985, Oct-08, Volume: 116, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Clomipramine; Corpus Striatum; Desipramine; Dopamine; Fluoxetine; Male; Mice; Mice, Inbred C57BL; Nomifensine; Norepinephrine; Pyridines; Serotonin Antagonists

1985
Fluoxetine and desipramine selectively attenuate 2'-NH2-MPTP-induced depletions in serotonin and norepinephrine.
    European journal of pharmacology, 1993, Dec-07, Volume: 250, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Body Temperature; Brain Chemistry; Carrier Proteins; Chromatography, High Pressure Liquid; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters

1993
2'-NH2-MPTP in Swiss Webster mice: evidence for long-term (6-month) depletions in cortical and hippocampal serotonin and norepinephrine, differential protection by selective uptake inhibitors or clorgyline and functional changes in central serotonin neuro
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cerebral Cortex; Clorgyline; Desipramine; Fluoxetine; Hippocampus; Male; Mice; Monoamine Oxidase Inhibitors; MPTP Poisoning; Neurotransmitter Uptake Inhibitors; Norepinephrine; Paroxetine; Selegiline; Serotonin; Serotonin Receptor Agonists; Synaptic Transmission; Time Factors

1993
A novel approach to predicting P450 mediated drug metabolism. CYP2D6 catalyzed N-dealkylation reactions and qualitative metabolite predictions using a combined protein and pharmacophore model for CYP2D6.
    Journal of medicinal chemistry, 1999, Oct-07, Volume: 42, Issue:20

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Betaxolol; Cytochrome P-450 CYP2D6; Dealkylation; Fluoxetine; Loratadine; Models, Molecular; Pharmaceutical Preparations; Procainamide; Ritonavir; Substrate Specificity; Sumatriptan

1999
MPTP-induced neuroblast apoptosis in the subventricular zone is not regulated by dopamine or other monoamine transporters.
    Neurotoxicology, 2009, Volume: 30, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenergic Uptake Inhibitors; Adult Stem Cells; Animals; Apoptosis; Cerebral Ventricles; Desipramine; Dopamine Uptake Inhibitors; Drug Interactions; Fluoxetine; Gene Expression Regulation; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurotoxins; Neurotransmitter Transport Proteins; Piperazines; Selective Serotonin Reuptake Inhibitors; Tetrabenazine

2009
Fluoxetine prevents MPTP-induced loss of dopaminergic neurons by inhibiting microglial activation.
    Neuropharmacology, 2011, Volume: 60, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Cell Count; Coculture Techniques; Corpus Striatum; Cytokines; Dopamine; Fluoxetine; Male; Mice; Mice, Inbred C57BL; Microglia; MPTP Poisoning; NADPH Oxidases; Nerve Degeneration; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type II; Oxidative Stress; Recovery of Function; Rotarod Performance Test; Substantia Nigra

2011
Norfluoxetine Prevents Degeneration of Dopamine Neurons by Inhibiting Microglia-Derived Oxidative Stress in an MPTP Mouse Model of Parkinson's Disease.
    Mediators of inflammation, 2018, Volume: 2018

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Dopaminergic Neurons; Fluoxetine; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Microglia; Oxidative Stress; Parkinson Disease; Rats; Rats, Sprague-Dawley

2018