fluorouracil and zidovudine

fluorouracil has been researched along with zidovudine in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.96)	18.7374
1990's	23 (45.10)	18.2507
2000's	15 (29.41)	29.6817
2010's	11 (21.57)	24.3611
2020's	1 (1.96)	2.80

Authors

Authors	Studies
Cessac, JW; Chanh, TC; Delgado, AV; Schinazi, RF; Taraporewala, IB	1
Juodawlkis, A; Liotta, DC; McAtee, JJ; Schinazi, RF; Schlueter Wirtz, S; Shi, J; Tharnish, P	1
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Agelis, G; Botić, T; Cencic, A; Dolinsek, J; Komiotis, D; Tsoukala, E	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Agelis, G; Botić, T; Cencic, A; Komiotis, D; Manta, S	1
Agelis, G; Botić, T; Cencic, A; Komiotis, D; Tzioumaki, N	1
Agelis, G; Botić, T; Cencic, A; Komiotis, D; Tselios, T; Tzioumaki, N	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Celewicz, L; Gajecka, M; Klich, K; Kubicka, MM; Przybylski, P; Pyta, K; Ruszkowski, P	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Liu, Y; Xu, Z; Zhao, SJ	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Ashida, N; Baba, M; Ikeda, T; Machida, H; Sakata, S; Shigeta, S	1
Bigley, J; Clark, J; Clendennin, N; Corvese, D; Cummings, FJ; Darnowski, JW; Dudley, MN; Murray, C; Posner, MR; Weitberg, AB	1
Taniki, T; Weber, G; Zhen, YS	1
Nagai, M; Nakamura, H; Olah, E; Prajda, N; Szekeres, T; Weber, G	1
Kawasaki, K; Nagai, K; Suda, T; Yamaguchi, Y	1
Beitz, J; Browne, MJ; Brunetti, I; Calabresi, P; Clark, J; Corvese, D; Cummings, FJ; Curt, G; Darnowski, JW; Posner, MR	1
Brunetti, I; Calabresi, P; Darnowski, JW; Falcone, A; Goulette, FA	1
Ichikawa, S; Nagai, M; Natsumeda, Y; Weber, G	1
Kashani-Sabet, M; Scanlon, KJ; Sowers, LC	1
Allegra, CJ; Grogan, L; Sotos, GA	1
Henson, E; McClarty, G; Wang, LL	1
Beitz, JG; Bigley, JW; Browne, MJ; Clark, JW; Cummings, FJ; Damowski, JW; Weitberg, AB	1
Oh-hara, T; Tsuruo, T; Yusa, K	1
Chandrasekaran, B; Duch, DS; Kute, TE	1
Brunetti, I; Conte, PF; Danesi, R; Dargenio, F; Del Tacca, M; Falcone, A; Nethersell, AB; Pfanner, E	1
Allegrini, G; Andreuccetti, M; Antonuzzo, A; Conte, PF; Danesi, R; Del Tacca, M; Falcone, A; Malvaldi, G	1
Akerley, W; Beitz, J; Bigley, J; Browne, M; Clark, J; Cole, B; Cummings, F; Darnowski, J; Kennedy, T; Sikov, W; Wanebo, H; Weitberg, A	1
Findenig, G; Fritzer-Szekeres, M; Jaeger, W; Mader, RM; Steger, GG; Szekeres, T	1
Kato, M; Kuroda, D; Ohyanagi, H; Yasuda, C	1
Allegrini, G; Andreuccetti, M; Antonuzzo, A; Brunetti, I; Conte, PF; Danesi, R; Del Tacca, M; Falcone, A; Lencioni, M; Malvaldi, G; Pfanner, E	1
Gao, WY; Johns, DG; Mitsuya, H; Tanaka, M	1
Büchele, T; Dempke, W; Grothey, A; Schmoll, HJ	1
Horowitz, D; King, AG	1
Broccoli, D; Brown, T; Rogatko, A; Sigurdson, E	1
Akiyama, S; Baba, M; Furukawa, T; Gotanda, T; Haraguchi, M; Hongye, Z; Nakagawa, M; Sumizawa, T; Tachiwada, T; Tsuneyoshi, K	1
Goltz, D; Jauch, C; Schott, H; Schott, TC; Schwendener, RA	1
Du, L; Jin, Y; Yang, F	1
Jena, G; Kansara, BR; Khan, S; Kushwaha, S; Shekh, K	1

Reviews

4 review(s) available for fluorouracil and zidovudine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships. European journal of medicinal chemistry, 2019, Dec-01, Volume: 183 Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triazoles	2019
Preclinical and clinical aspects of biomodulation of 5-fluorouracil. Cancer treatment reviews, 1994, Volume: 20, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cisplatin; Colorectal Neoplasms; DNA, Neoplasm; Fluorouracil; Humans; Idoxuridine; Immunologic Factors; Interferons; Leucovorin; Methotrexate; Mice; Phosphonoacetic Acid; RNA, Neoplasm; Uracil; Uridine; Zidovudine	1994
Where do we stand with 5-fluorouracil? Seminars in oncology, 1999, Volume: 26, Issue:6 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Chronotherapy; Colorectal Neoplasms; Dipyridamole; Drug Synergism; Fluorouracil; Humans; Interferons; Leucovorin; Levamisole; Methotrexate; Phosphonoacetic Acid; Radiation-Sensitizing Agents; Trimetrexate; Zidovudine	1999

Trials

6 trial(s) available for fluorouracil and zidovudine

Article	Year
High-dose intravenous zidovudine with 5-fluorouracil and leucovorin. A phase I trial. Cancer, 1992, Dec-15, Volume: 70, Issue:12 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Middle Aged; Neoplasms; Zidovudine	1992
Oral zidovudine, continuous-infusion fluorouracil, and oral leucovorin calcium: a phase I study. Journal of the National Cancer Institute, 1990, Nov-07, Volume: 82, Issue:21 Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; DNA; DNA Damage; Dose-Response Relationship, Drug; Drug Evaluation; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Male; Middle Aged; Neoplasms; Zidovudine	1990
Phase I trial of high-dose infused zidovudine combined with leucovorin plus fluorouracil. Cancer investigation, 1995, Volume: 13, Issue:5 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasms; Zidovudine	1995
Intravenous azidothymidine with fluorouracil and leucovorin: a phase I-II study in previously untreated metastatic colorectal cancer patients. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:3 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Confidence Intervals; Drug Administration Schedule; Female; Fluorouracil; Humans; Hypotension; Infusions, Intravenous; Leucovorin; Male; Middle Aged; Zidovudine	1996
Phase II study of 5-fluoruracil leucovorin and azidothymidine in patients with metastatic colorectal cancer. Journal of cancer research and clinical oncology, 1996, Volume: 122, Issue:9 Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Male; Middle Aged; Zidovudine	1996
Maximum tolerable doses of intravenous zidovudine in combination with 5-fluorouracil and leucovorin in metastatic colorectal cancer patients. Clinical evidence of significant antitumor activity and enhancement of zidovudine-induced DNA single strand break Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:6 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; DNA Damage; DNA, Neoplasm; DNA, Single-Stranded; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Injections, Intravenous; Leucovorin; Leukocytes, Mononuclear; Male; Middle Aged; Neoplasm Metastasis; Zidovudine	1997

Other Studies

41 other study(ies) available for fluorouracil and zidovudine

Article	Year
HIV-1 neutralization and tumor cell proliferation inhibition in vitro by simplified analogues of pyrido[4,3,2-mn]thiazolo[5,4-b]acridine marine alkaloids. Journal of medicinal chemistry, 1992, Jul-24, Volume: 35, Issue:15 Topics: Alkaloids; Antiviral Agents; Cell Division; Cells, Cultured; Cytopathogenic Effect, Viral; DNA; HIV-1; Humans; Interferon-gamma; Lymphocytes; Radioimmunoassay; Structure-Activity Relationship; Tumor Cells, Cultured	1992
Synthesis and biological evaluation of 2',3'-didehydro-2',3'- dideoxy-5-fluorocytidine (D4FC) analogues: discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase. Journal of medicinal chemistry, 1999, Mar-11, Volume: 42, Issue:5 Topics: Animals; Anti-HIV Agents; Antineoplastic Agents; Drug Screening Assays, Antitumor; HIV Reverse Transcriptase; Humans; Organophosphates; Rats; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured; Zalcitabine	1999
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
An efficient synthesis of 3-fluoro-5-thio-xylofuranosyl nucleosides of thymine, uracil, and 5-fluorouracil as potential antitumor or/and antiviral agents. Bioorganic & medicinal chemistry, 2007, May-01, Volume: 15, Issue:9 Topics: Antineoplastic Agents; Antiviral Agents; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Intestines; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Rotavirus; Stereoisomerism; Structure-Activity Relationship; Thymine; Uracil; Xylose; Zidovudine	2007
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Unsaturated fluoro-ketopyranosyl nucleosides: synthesis and biological evaluation of 3-fluoro-4-keto-beta-d-glucopyranosyl derivatives of N(4)-benzoyl cytosine and N(6)-benzoyl adenine. European journal of medicinal chemistry, 2008, Volume: 43, Issue:2 Topics: Adenine; Antiviral Agents; Cell Line, Tumor; Cytosine; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Rotavirus; Spectrometry, Mass, Electrospray Ionization	2008
Exomethylene pyranonucleosides: efficient synthesis and biological evaluation of 1-(2,3,4-trideoxy-2-methylene-beta-d-glycero-hex-3-enopyranosyl)thymine. Bioorganic & medicinal chemistry, 2007, Aug-15, Volume: 15, Issue:16 Topics: Antiviral Agents; Cell Line; Cell Proliferation; Inhibitory Concentration 50; Methylation; Molecular Structure; Nucleosides; Structure-Activity Relationship; Thymine	2007
Synthesis and molecular modelling of unsaturated exomethylene pyranonucleoside analogues with antitumor and antiviral activities. European journal of medicinal chemistry, 2008, Volume: 43, Issue:7 Topics: Antineoplastic Agents; Antiviral Agents; Caco-2 Cells; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleosides; Rotavirus; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Synthesis, Antibacterial, and Anticancer Evaluation of Novel Spiramycin-Like Conjugates Containing C(5) Triazole Arm. Journal of medicinal chemistry, 2016, 09-08, Volume: 59, Issue:17 Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Line, Tumor; Cycloaddition Reaction; Drug Screening Assays, Antitumor; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Models, Molecular; Solubility; Spiramycin; Structure-Activity Relationship; Thermodynamics; Triazoles	2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
In vitro drug combination of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil with anti-human immunodeficiency virus or anticancer nucleosides. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:1 Topics: Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Cytarabine; Drug Combinations; Floxuridine; Fluorouracil; Herpesvirus 3, Human; HIV-1; Humans; Zidovudine	1992
Azidothymidine and dipyridamole as biochemical response modifiers: synergism with methotrexate and 5-fluorouracil in human colon and pancreatic carcinoma cells. Oncology research, 1992, Volume: 4, Issue:2 Topics: Adenocarcinoma; Cell Division; Cell Line; Cell Survival; Colonic Neoplasms; Dipyridamole; DNA Replication; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; Humans; Methotrexate; Pancreatic Neoplasms; Thymidine; Tumor Stem Cell Assay; Zidovudine	1992
AZT: a biochemical response modifier of methotrexate and 5-fluorouracil cytotoxicity in human ovarian and pancreatic carcinoma cells. Cancer communications, 1991, Volume: 3, Issue:4 Topics: Animals; Binding, Competitive; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Female; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Methotrexate; Ovarian Neoplasms; Pancreatic Neoplasms; Rats; Thymidine; Thymidine Kinase; Tumor Cells, Cultured; Zidovudine	1991
[Effects of L-carnosine on blood cells and biomembrane]. Nihon seirigaku zasshi. Journal of the Physiological Society of Japan, 1990, Volume: 52, Issue:10 Topics: Animals; Blood Cell Count; Carnosine; Cell Membrane; Erythrocytes; Fluorouracil; Leukocytes; Lysosomes; Male; Mitomycin; Mitomycins; Phenylhydrazines; Rats; Rats, Inbred Strains; Zidovudine	1990
5-Fluorouracil enhances azidothymidine cytotoxicity: in vitro, in vivo, and biochemical studies. Cancer research, 1990, Jul-01, Volume: 50, Issue:13 Topics: Animals; Cell Division; Colonic Neoplasms; DNA, Neoplasm; Drug Administration Schedule; Drug Synergism; Female; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Pyrimidine Nucleosides; Thymidylate Synthase; Tumor Cells, Cultured; Zidovudine	1990
Azidothymidine inhibition of thymidine kinase and synergistic cytotoxicity with methotrexate and 5-fluorouracil in rat hepatoma and human colon cancer cells. Cancer communications, 1990, Volume: 2, Issue:4 Topics: Animals; Cell Line; Cell Survival; Colonic Neoplasms; Drug Synergism; Fluorouracil; Humans; Kinetics; Liver Neoplasms, Experimental; Methotrexate; Rats; Thymidine; Thymidine Kinase; Tumor Cells, Cultured; Zidovudine	1990
Overexpression of DNA replication and repair enzymes in cisplatin-resistant human colon carcinoma HCT8 cells and circumvention by azidothymidine. Cancer communications, 1989, Volume: 1, Issue:4 Topics: Cell Line; Cisplatin; Colonic Neoplasms; DNA Polymerase I; DNA Polymerase II; DNA Repair; DNA Replication; Drug Resistance; Etoposide; Floxuridine; Fluorouracil; Humans; Methotrexate; Tetrahydrofolate Dehydrogenase; Thymidine Kinase; Thymidylate Synthase; Tumor Cells, Cultured; Zidovudine	1989
Characterization of trimethoprim- and sulphisoxazole-resistant Chlamydia trachomatis. Molecular microbiology, 1994, Volume: 14, Issue:2 Topics: Adenosine Triphosphate; Animals; Chlamydia trachomatis; DNA, Bacterial; Drug Resistance, Microbial; Fluorouracil; Guanosine Triphosphate; L Cells; Methotrexate; Mice; Microbial Sensitivity Tests; Mutation; Phenotype; RNA, Bacterial; Sulfisoxazole; Thymidine; Trimethoprim; Uracil; Zidovudine	1994
Induction of resistance to 1-beta-D-arabinofuranosylcytosine in human H9 cell line by simian immunodeficiency virus. Biochemical and biophysical research communications, 1995, Jan-17, Volume: 206, Issue:2 Topics: Cell Division; Cell Line; Cell Survival; Cytarabine; Cytidine Deaminase; Drug Resistance; Fluorouracil; Humans; Leukemia-Lymphoma, Adult T-Cell; Mercaptopurine; Simian Immunodeficiency Virus; Tetrahydrouridine; Tumor Cells, Cultured; Vidarabine; Zalcitabine; Zidovudine	1995
Synchronization of cells in the S phase of the cell cycle by 3'-azido-3'-deoxythymidine: implications for cell cytotoxicity. Cancer chemotherapy and pharmacology, 1995, Volume: 35, Issue:6 Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Division; Cell Survival; Colonic Neoplasms; Computer Simulation; DNA, Neoplasm; Drug Synergism; Flow Cytometry; Fluorouracil; Humans; Leukemia; Melanoma; Methotrexate; Pancreatic Neoplasms; S Phase; Tumor Cells, Cultured; Zidovudine	1995
Azidothymidine in combination with 5-fluorouracil in human colorectal cell lines: in vitro synergistic cytotoxicity and DNA-induced strand-breaks. European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:7 Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Death; Colorectal Neoplasms; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; Humans; Tumor Cells, Cultured; Zidovudine	1996
Modulation of 5-fluorouracil resistance in human colon tumor cell lines by azidothymidine. Oncology research, 1996, Volume: 8, Issue:5 Topics: Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Resistance; Drug Synergism; Fluorouracil; Humans; Orotate Phosphoribosyltransferase; Thymidine Kinase; Thymidine Phosphorylase; Thymidylate Synthase; Tumor Cells, Cultured; Uridine Phosphorylase; Zidovudine	1996
Experimental studies on potentiation of the antitumor activity of 5-fluorouracil with 3'-azido-3'-deoxythymidine for the gastric cancer cell line MKN28 in vivo. Japanese journal of cancer research : Gann, 1997, Volume: 88, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Drug Synergism; Female; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Stomach Neoplasms; Thymidine Kinase; Tumor Cells, Cultured; Zidovudine	1997
Suppression of replication of multidrug-resistant HIV type 1 variants by combinations of thymidylate synthase inhibitors with zidovudine or stavudine. Molecular pharmacology, 1999, Volume: 55, Issue:3 Topics: Anti-HIV Agents; Antimetabolites; Drug Interactions; Drug Resistance, Microbial; Drug Resistance, Multiple; Floxuridine; Fluorouracil; HIV-1; Humans; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Thymidylate Synthase; Thymine Nucleotides; Virus Replication; Zidovudine	1999
Colorimetric determination of inhibition of hematopoietic progenitor cells in soft agar. Journal of immunological methods, 2000, Oct-20, Volume: 244, Issue:1-2 Topics: Animals; Antimetabolites; Antimetabolites, Antineoplastic; Antiviral Agents; Colony-Forming Units Assay; Colony-Stimulating Factors; Colorimetry; Coloring Agents; Cytarabine; Cytokines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Fluorouracil; Ganciclovir; Growth Inhibitors; Hematopoietic Stem Cells; Humans; Inhibitory Concentration 50; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Tetrazolium Salts; Thiazoles; Zidovudine	2000
Telomerase inhibition using azidothymidine in the HT-29 colon cancer cell line. Annals of surgical oncology, 2003, Volume: 10, Issue:8 Topics: Analysis of Variance; Blotting, Southern; Colonic Neoplasms; Fluorouracil; HT29 Cells; Humans; Reverse Transcriptase Inhibitors; Telomerase; Tumor Cells, Cultured; Zidovudine	2003
Induction of thymidine phosphorylase expression by AZT contributes to enhancement of 5'-DFUR cytotoxicity. Cancer letters, 2006, Dec-08, Volume: 244, Issue:2 Topics: Antimetabolites; Cell Survival; Drug Synergism; Floxuridine; Fluorouracil; Humans; Thymidine Phosphorylase; Transfection; U937 Cells; Zidovudine	2006
N⁴-[Alkyl-(hydroxyphosphono)phosphonate]-cytidine-new drugs covalently linking antimetabolites (5-FdU, araU or AZT) with bone-targeting bisphosphonates (alendronate or pamidronate). Bioorganic & medicinal chemistry, 2011, Jun-01, Volume: 19, Issue:11 Topics: Alendronate; Animals; Antimetabolites, Antineoplastic; Arabinofuranosyluracil; Bone and Bones; Bone Density Conservation Agents; Cell Line, Tumor; Cytidine; Diphosphonates; Drug Screening Assays, Antitumor; Durapatite; Fluorouracil; Humans; Macrophages; Mice; Pamidronate; Uridine; Zidovudine	2011
Nanoassemblies containing a fluorouracil/zidovudine glyceryl prodrug with phospholipase A2-triggered drug release for cancer treatment. Colloids and surfaces. B, Biointerfaces, 2013, Dec-01, Volume: 112 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Carriers; Drug Delivery Systems; Female; Fluorouracil; HCT116 Cells; Humans; Mice; Nanoparticles; Phospholipases A2; Prodrugs; Tissue Distribution; Zidovudine	2013
3-Aminobenzamide--a PARP inhibitor enhances the sensitivity of peripheral blood micronucleus and comet assays in mice. Toxicology mechanisms and methods, 2014, Volume: 24, Issue:5 Topics: Animals; Benzamides; Comet Assay; Cyclophosphamide; Fluorouracil; Furosemide; Male; Mice; Micronucleus Tests; Mutagens; Poly(ADP-ribose) Polymerase Inhibitors; Zidovudine	2014