fluorouracil and uridine monophosphate

fluorouracil has been researched along with uridine monophosphate in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's5 (38.46)18.2507
2000's2 (15.38)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Clynes, MM; Duke, EJ1
Cloos, J; Noordhuis, P; Peters, GJ; Pinedo, HM; Smid, K; van der Wilt, CL1
Laurensse, E; Meijer, S; Peters, GJ; Pinedo, HM; Smid, K; van der Wilt, CL; van Groeningen, CJ1
Grem, JL1
de Montigny, J; Jund, R; Kern, L; Lacroute, F1
Elias, L; Sandoval, JM1
Ahmed, NK1
Brennan, RG; Carter, D; Roos, DS; Schumacher, MA; Scott, DM; Ullman, B1
Hoskins, J; Scott Butler, J1
Agudo, R; Arias, A; Domingo, E; Escarmís, C; Jorge, A; Marina, A; Pariente, N; Perales, C1
Akiyama, S; Che, XF; Furukawa, T; Ikeda, R; Kanekura, T; Kanzaki, T; Mataki, H; Matsushita, S; Minami, K; Miyadera, K; Nishizawa, Y; Tabata, S; Tajitsu, Y; Takeda, Y; Ushiyama, M; Yamada, K; Yamamoto, M1
Fairlamb, AH; Ong, HB; Patterson, S; Sienkiewicz, N; Wyllie, S1
Aradi, J; Benkő, I; Géresi, K; Megyeri, A; Németh, J; Szabó, B; Szabó, Z1

Reviews

1 review(s) available for fluorouracil and uridine monophosphate

ArticleYear
Biochemical modulation of fluorouracil by dipyridamole: preclinical and clinical experience.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3

    Topics: Colonic Neoplasms; Deoxyuridine; Dipyridamole; DNA Damage; DNA, Neoplasm; Drug Interactions; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Methotrexate; Nucleosides; Nucleotides; RNA, Neoplasm; Thymidine; Tumor Cells, Cultured; Uridine Monophosphate

1992

Other Studies

12 other study(ies) available for fluorouracil and uridine monophosphate

ArticleYear
Altered pyrimidine-salvage metabolism in a 5-fluorouracil-resistant mutant of Drosophila melanogaster.
    Biochemical Society transactions, 1976, Volume: 4, Issue:5

    Topics: Animals; Drosophila melanogaster; Drug Resistance; Fluorouracil; Mutation; Pentosyltransferases; Pyrimidines; Species Specificity; Thymidine Kinase; Uridine Kinase; Uridine Monophosphate

1976
Effect of folinic acid on fluorouracil activity and expression of thymidylate synthase.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3

    Topics: Animals; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Leucovorin; Mice; Mice, Inbred BALB C; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured; Uridine Monophosphate

1992
Time course of inhibition of thymidylate synthase in patients treated with fluorouracil and leucovorin.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3

    Topics: Adult; Aged; Colorectal Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Thymidylate Synthase; Time Factors; Uridine Monophosphate

1992
The FUR1 gene of Saccharomyces cerevisiae: cloning, structure and expression of wild-type and mutant alleles.
    Gene, 1990, Apr-16, Volume: 88, Issue:2

    Topics: Alleles; Amino Acid Sequence; Base Sequence; Chromosome Deletion; Cloning, Molecular; DNA Mutational Analysis; DNA, Recombinant; Fluorouracil; Genes, Fungal; Molecular Sequence Data; Orotate Phosphoribosyltransferase; Pentosyltransferases; Plasmids; Saccharomyces cerevisiae; Uracil; Uridine Monophosphate

1990
Interferon effects upon fluorouracil metabolism by HL-60 cells.
    Biochemical and biophysical research communications, 1989, Sep-15, Volume: 163, Issue:2

    Topics: Fluorouracil; Humans; Interferon Type I; Recombinant Proteins; Thymidylate Synthase; Tumor Cells, Cultured; Uridine Monophosphate

1989
Enzymes of the de novo and salvage pathways for pyrimidine biosynthesis in normal colon, colon carcinoma, and xenografts.
    Cancer, 1984, Oct-01, Volume: 54, Issue:7

    Topics: Adenocarcinoma; Animals; Carboxy-Lyases; Colon; Colonic Neoplasms; Fluorouracil; Humans; Intestinal Mucosa; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Pentosyltransferases; Phosphotransferases; Transplantation, Heterologous; Uracil Nucleotides; Uridine Kinase; Uridine Monophosphate

1984
Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
    The EMBO journal, 1998, Jun-15, Volume: 17, Issue:12

    Topics: Amino Acid Sequence; Animals; Antimetabolites; Conserved Sequence; Crystallography, X-Ray; Dimerization; Drug Design; Fluorouracil; Models, Molecular; Molecular Sequence Data; Pentosyltransferases; Prodrugs; Protein Conformation; Protozoan Proteins; Pyrimidines; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Toxoplasma; Uridine Monophosphate

1998
Evidence for distinct DNA- and RNA-based mechanisms of 5-fluorouracil cytotoxicity in Saccharomyces cerevisiae.
    Yeast (Chichester, England), 2007, Volume: 24, Issue:10

    Topics: Antimetabolites, Antineoplastic; DNA; DNA Repair; Fluorouracil; RNA; Saccharomyces cerevisiae; Uracil; Uridine Monophosphate

2007
Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis.
    Journal of molecular biology, 2008, Oct-10, Volume: 382, Issue:3

    Topics: Animals; Antimetabolites; Base Sequence; Cell Line; Fluorouracil; Foot-and-Mouth Disease Virus; Genome, Viral; Humans; Mutagenesis; RNA-Dependent RNA Polymerase; RNA, Viral; Uridine Monophosphate; Uridine Triphosphate; Viral Proteins; Virus Replication

2008
The role of thymidine phosphorylase in the induction of early growth response protein-1 and thrombospondin-1 by 5-fluorouracil in human cancer carcinoma cells.
    International journal of oncology, 2010, Volume: 36, Issue:5

    Topics: Antimetabolites, Antineoplastic; Carcinoma; Cell Line, Tumor; Dideoxynucleotides; Early Growth Response Protein 1; Fluorodeoxyuridylate; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Skin Neoplasms; Stomach Neoplasms; Thrombospondin 1; Thymidine Phosphorylase; Uridine Monophosphate

2010
Trypanosoma brucei (UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy.
    Molecular microbiology, 2013, Volume: 90, Issue:2

    Topics: Amides; Animals; Biological Transport; Cell Line; Deoxyuridine; Fluorouracil; Gene Knockout Techniques; Mice; Multienzyme Complexes; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Transfection; Trypanocidal Agents; Trypanosoma brucei brucei; Uracil; Uridine; Uridine Monophosphate; Virulence

2013
Myelotoxicity of carboplatin is increased in vivo in db/db mice, the animal model of obesity-associated diabetes mellitus.
    Cancer chemotherapy and pharmacology, 2015, Volume: 75, Issue:3

    Topics: Animals; Antineoplastic Agents; Bone Marrow Diseases; Carboplatin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Doxorubicin; Fluorouracil; Granulocyte-Macrophage Progenitor Cells; Male; Mice; Mice, Inbred C57BL; Neutropenia; Obesity; Thionucleotides; Uridine Monophosphate

2015