fluorouracil and thymidine

fluorouracil has been researched along with thymidine in 351 studies

Research

Studies (351)

TimeframeStudies, this research(%)All Research%
pre-1990271 (77.21)18.7374
1990's51 (14.53)18.2507
2000's19 (5.41)29.6817
2010's9 (2.56)24.3611
2020's1 (0.28)2.80

Authors

AuthorsStudies
Chen, MS; Prusoff, WH; Schinazi, RF1
Forsthoefel, PF; Williams, ML1
Faufmann, M; MAttern, J; Volm, M; Wayss, K1
Chu, BC; Lawley, PD1
Baker, MS; Benedict, WF; Heidelberger, C; Jones, PA; Mondal, S; Rapp, U1
Pfefferkorn, ER; Pfefferkorn, LC1
Pogosiants, EE; Sokova, OI; Volgareva, GM1
Cass, CE; Lynch, TP; Paterson, AR1
Blend, MJ; Forsthoefel, PF; Snow, JW1
Danhauser, L; Rustum, YM; Wang, G1
Bowen, D; Diasio, RB; Goldman, ID1
Hopkins, HA; Wakefield, JA1
DeMarchi, JM; Kaplan, AS1
Chavaudra, N; Malaise, EP1
Santelli, G; Valeriote, F2
Klahr, C; Presant, CA; Ratkin, GA; Vogel, SJ1
Friedman, MA; Sadée, W1
Goldin, A; Wolpert-Defilippes, MK1
Danhauser, LL; Rustum, YM2
Carrico, CK; Glazer, RI1
Reinhard, P; Schluchter, M1
Breland, JC; Carter, GL; Cory, JG1
Akao, T; Fujimoto, S; Itoh, B; Itoh, K; Kitsukawa, Y; Takahashi, M1
Alexander, JA; Wheeler, GP1
Redmann, K; Walliser, S1
Gloor, M; Schnyder, UW; Vollweiler, B; Wirth, H2
Hoshi, A; Kuretani, K; Yoshida, M1
de Loecker, W; van der Schueren, G1
Rizki, RM; Rizki, TM3
Camplejohn, RS; Maurer, W; Schultze, B1
Young, RC1
Håkansson, L1
Cabradilla, CD; Toliver, AP1
Jentzsch, K1
Dahn, I; Håkansson, L; Huldt, B1
Der, S; Jonek, JJ; Konecki, J1
Cohen, AM1
Feinendegen, LE; Myers, DK1
Chabner, BA; Myers, CE; Young, RC1
Fujieda, S; Ohtsubo, T; Saito, H; Tanigawa, N1
Arredondo, MA; Guimaraes, MA; Rustum, YM; Yin, MB; Zhang, ZG1
Ng, TC; Sijens, PE1
Cloos, J; Noordhuis, P; Peters, GJ; Pinedo, HM; Smid, K; van der Wilt, CL1
Hoffman, M; O'Connor, CJ; Schwartz, EL; Wadler, S1
Grem, JL1
Taniki, T; Weber, G; Zhen, YS1
Jeyanthi, R; Nagarajan, B; Rao, KP1
De Clercq, E; Marquez, VE; Murase, J1
Rustum, YM; Yin, MB1
Nagai, M; Nakamura, H; Olah, E; Prajda, N; Szekeres, T; Weber, G1
Cravo, ML; Mason, JB; Rosenberg, IH; Selhub, J1
Glass, J; Neefe, JR1
Choo, PH; Kitada, S; Lee, DA; Shapourifar-Tehrani, S; Wong, VK1
Hampson, J; Lord, BI; Redmond, S; Slocombe, P1
Dvilansky, A; Kafka, M; Nathan, I1
Imai, S; Morimoto, H; Nio, Y; Shiraishi, T; Tobe, T; Tseng, CC; Tsubono, M1
Holbrook, CT; Klann, RC; Nyce, J1
Goldberg, RM; Krook, JE; Kugler, JW; Laurie, JA; Moertel, CG; O'Connell, MJ; Pfeifle, DM; Rubin, J; Wieand, HS; Windschitl, HE1
Greenhalgh, DA; Parish, JH1
Germain, G; Houghton, JA; Houghton, PJ; Pennington, J; Radparvar, S; Rahman, A1
Ichikawa, S; Nagai, M; Natsumeda, Y; Weber, G1
Akazawa, S; Ayusawa, D; Kumai, R; Seno, T; Shimizu, K; Yoshida, K1
Laurensse, E; Leyva, A; Peters, GJ; Pinedo, HM2
Kane, MA; Raptis, G; Roth, E; Schreiber, C; Waxman, S1
Arbuck, SG; Creaven, PJ; Herrera, L; Mittelman, A; Petrelli, N; Rustum, YM; Trave, F; Zakrzewski, SF1
Milstone, LM; Schwartz, PM1
Burdett, DN; Chen, YP; Shah, RM1
Darland, G; Kaplan, L; Rosenbach, M1
Alcober, V; Pellicer, JA; Pertusa, J1
Kusumoto, H; Kusumoto, T; Maehara, Y; Sakaguchi, Y; Sugimachi, K1
Farquhar, D; Freed, JJ; Hampton, A1
Buroker, TR; Cullinan, SA; Everson, LK; Fleming, TR; Klaassen, DJ; Krook, JE; Laurie, JA; Mailliard, JA; Marschke, RF; Moertel, CG1
Armstrong, RD; Cadman, EC; Takimoto, CH1
Bollag, W; Hartmann, HR1
Bertino, JR; Mini, E; Moroson, BA1
Bertino, JR; Coronnello, M; Criscuoli, L; Gualtieri, M; Mazzei, T; Mini, E; Periti, P1
Lönn, S; Lönn, U1
Lin, FH; Williams, WM1
Fantes, F; Hajek, AS; Mallick, KS; Parrish, RK; Rivera, AH1
Hattori, T; Hirabayashi, N; Niimi, K; Niimoto, M; Nishiyama, M; Noso, Y; Toge, T; Yamaguchi, M1
Hattori, T; Hirabayashi, N; Niimoto, M; Nishiyama, M; Nosoh, Y; Toge, T; Yamaguchi, M1
Abe, Y; Ido, T; Ishiwata, K; Matsuzawa, T; Murakami, M1
Benedict, WF; Heidelberger, C; Peterson, AR1
Srivastava, BI1
Hoth, DF; King, SA; Leyland-Jones, B; O'Dwyer, PJ1
Bitny-Szlachto, S; Panfil, B1
Leyland-Jones, B; O'Dwyer, PJ1
Inokuchi, K; Maehara, Y; Masuda, H; Matsuoka, H; Sugimachi, K1
Fischer, PH; Grem, JL1
Alama, A; Canavese, G; Conte, PF; Di Marco, E; Nicolin, A; Rosso, R1
O'Dea, RF; Ramnaraine, ML; Tuchman, M2
Meyer, JS1
Kennedy, KA; Klubes, P; Parker, WB1
Germain, G; Houghton, JA; Houghton, PJ; Torrance, PM1
el-Assouli, SM1
Rustum, YM1
Gonçalves, O; Meuth, M; Trudel, M1
Ashman, CR; Davidson, RL; Kaufman, ER1
Balzarini, J; Bricaud, H; De Clercq, E; Desgranges, C; Drouillet, F; Herdewijn, P; Razaka, G1
Akazawa, S; Ayusawa, D; Kumai, R; Seno, T; Shimizu, K; Yoshida, S1
Chun, H; Kemeny, N; Lynch, G; Martin, D; Young, C1
Bedikian, A; Bodey, GP; Chiuten, DF; Freireich, EJ; Valdivieso, M1
Hajek, AS; Mallick, KS; Parrish, RK1
Bedikian, A; Benvenuto, JA; Bodey, GP; Chiuten, DF; Freireich, EJ; Loo, TL; Miller, A; Valdivieso, M1
Conte, PF; Drewinko, B; Fraschini, G1
Kanamoto, Y1
Briggs, L; Parry, N; Recher, L; Whitescarver, J1
Galt, RM; Knock, FE; Oester, YT; Sylvester, R2
Doolittle, CH; Hahn, GA; Mandel, HG1
Haki, K; Iwasa, H; Murakami, T; Sekizuka, H1
Goerttler, K; Kaufmann, M; Mattern, J; Volm, M; Wayss, K1
Seidel, HJ; Wegner, LA1
Wüst, GP1
Hahn, GA; Mandel, HG1
Bresler, SK; Mosevitskii, MI; Vyacheslavov, LG1
Craig, JM; Kury, G1
Beridze, TG; Cherkashina, NA; Odintsova, MS; Sissakian, NM1
Foley, GE; Lazarus, H1
Wolberg, WH3
Hoshino, T; Nagai, M; Sano, K1
Seeber, S; Warnecke, P; Weitzel, G1
Kummer, D1
Beck, CF; Ingraham, JL; Neuhard, J; Thomassen, E1
Williams, JP1
Hanna, C1
Bremer, K; Pinney, RJ; Smith, JT1
Ben-Porat, T; Kaplan, AS; Tennant, RW1
Bensch, KG; Fong, CK; Hsiung, GD1
Foltz, EL1
Baba, K; Minekawa, Y; Takahashi, M1
Birg, F; Meyer, G1
Dickson, JA; Suzangar, M1
Erbe, J; Plagemann, PG1
Bullock, J; Khalil, FL; Lea, MA; Morris, HP1
Clarkson, SG1
Bean, B; Tomasz, A1
Mikhailova, LN; Zalmanzon, ES1
Bull, FE; Ruddon, RW; Wheeler, RH1
Krishnan, D; Painter, RB1
Harrap, KR; Tattersall, MH1
Rosenbaum-Oliver, D; Zamenhof, S1
Boyle, JM1
Bolund, C; Sköld, O1
Schlammadinger, J; Szabó, G1
Curry, MC; Dustin, R; Kahn, G1
Lipkin, M; Troncale, FJ1
Peckham, MJ1
Douthit, HA; Rizki, RM; Rizki, TM1
Leskova, S; Merkulov, M1
Johanson, KJ1
Aingorn, ED; Akif'ev, AP2
Edlis, H; Herbert, V; Tisman, G1
Lee, TC; Maruyama, Y; Sullivan, S1
Ganzer, U; Nitze, HR; Vosteen, KH1
Painter, RB; Young, BR1
Bärwolff, D; Langen, P; Matthes, E1
Mattern, J; Volm, M; Wayss, K1
Birkett, S; Salaman, DF1
Benckhuijsen, C1
Velousova, AK1
Sköld, O1
Boyle, JM; Schenley, RL; Swenson, PA1
Mueller, M; Russo, V; Selzer, G; Stahl, FW; Yegian, CD1
Mandel, HG; Reich, M1
Hogg, L; Kemp, S; Wachsman, JT1
Bloch, A; Fleysher, MH; Hall, RH; Maue, RJ; Thedford, R1
Bass, RE; Saunders, GF; Saunders, PP1
Baranski, K; Bardos, TJ; Bloch, A; Kalman, TI1
Hand, RE; Tennant, RW1
Leskova, SG; Merkulov, MF1
Bruce, WR; Eaves, AC1
Cooper, GM; Dunning, WF; Greer, S1
Blunt, RJ; Jones, R1
Rowe-Jones, DC1
Nitze, HR; Rosemann, G1
Greenberg, DM; Reeves, WJ; Seid, A1
Hall, TC; Kessel, D; Reyes, P1
Hara, H1
Hong, CI; Irvin, JL; Piantadosi, C1
Ansfield, FJ; Wolberg, WH1
Fujimoto, S; Miyoshi, T; Watanabe, Y; Watanuki, S1
Bielka, H; Langen, P; Stahl, J1
McGuire, WL; O'Malley, BW1
Chae, CB; Irvin, JL; Piantadosi, C1
Bruce, WR; Madoc-Jones, H1
Garvey, BI; Hayashi, TT1
Kowollik, G; Langen, P1
Galun, E; Torrey, JG1
Herbert, V; Waxman, S1
Baserga, R; McDonough, M; Sasaki, T; Shimkin, MB; Thatcher, D; Wieder, R1
Astaldi, G; Eridani, S; Giangrande, A; Ponti, GB; Valentini, R1
Jordan, RL; Schumacher, H; Wilson, JG1
Jordan, RL; Schumacher, HJ; Wilson, JG1
Cailleau, R; Reeves, WJ1
Ben-Porat, T; Kamiya, T; Kaplan, AS1
Booth, BA; Sartorelli, AC1
Clarkson, B; O'Connor, A; Ohkita, T; Ota, K1
Galun, E; Gressel, J1
Green, WR; Lis, AW1
Bruce, WR1
Gallant, JA; Weisberg, RA1
Adams, JE; Breed, NL; Valenti, C1
Myers, CE1
Cerna, I; Klubes, P; Meldon, MA1
Mandel, HG1
Ellims, PH1
Maurer-Schultze, B1
Dolnick, BJ; Pink, JJ1
Benz, C; Cadman, E; Choti, M; Newcomer, L1
Engelbrecht, C; Lewan, L; Ljungquist, I; Yngner, T1
Au, JL; Creaven, PJ; Ledesma, EJ; Mittelman, A; Rustum, YM1
Egan, E; Herrick, D; Kufe, DW; Major, PP1
Kimura, K; Tanaka, M; Yoshida, S1
Cooper, AJ; Goeting, N; Morgan, GR; Taylor, I; Trotter, GA1
Powis, G1
Teufel, G1
Shapiro, WR; Young, DF1
Allegra, CJ; Chabner, BA; Curt, GA; Fine, RL; Yeh, GW1
Fujii, S; Shirasaka, T1
Burchenal, D; Clarkson, BD; Fried, J; Murgo, AJ; Strife, A; Vale, KL; Woodcock, T; Young, CW1
Fukuoka, K; Ishitsuka, H; Itoga, A; Maruyama, HB; Miwa, M; Takemoto, K1
Day, JL; Mandel, HG; Maybaum, J; Sadee, W; Ullman, B1
Au, J; Creaven, P; Mittelman, A; Petrelli, NJ; Rustum, Y; Sternberg, A1
Hahn, RG; Kvols, LK; Moertel, CG; O'Connell, MJ; Rubin, J; Schutt, AJ1
Mackinnon, WB; Nott, SE; Piper, AA; Tattersall, MH1
Hoshino, T; Kobayashi, S1
Clarkson, BD; Doblin, JM; Fried, J; Perez, AG2
Casper, ES; Kemeny, N; Martin, DS; Michaelson, RA; Young, CW1
Langen, P; Liermann, B; Matthes, E1
Boumah, CE; Kaplan, JG; Setterfield, G1
Leyva, A; Pinedo, HM; Schornagel, JH1
Benvenuto, J; Drewinko, B; Freireich, EJ; Ho, DH; Loo, TL; Yang, LY1
Fujii, S; Fukushima, M; Ikenaka, K; Kitano, S; Maehara, Y; Nakamura, H; Shirasaka, T1
Arking, R; Kalata, K; Parente, A1
Jellinghaus, W; Maurer, W; Müller, V; Schultze, B; Weis, G1
Tschiersch, B1
Tattersall, MH1
Covey, JM; Straw, JA1
Martin, D; Nayak, R; Ritzi, E; Sawyer, R; Spiegelman, S; Stolfi, R1
Evans, RM; Hakala, MT; Laskin, JD1
Martin, DS; Nayak, R; Sawyer, RC; Spiegelman, S; Stolfi, RL; Woodcock, T; Young, CW1
Au, JL; Danhauser, L; Luccioni, C; Rustum, YM1
Al-Jurf, AS1
Gonçalves, O; Meuth, M; Thom, P1
Eiselt, M; Gloor, M; Wirth, H1
Clarke, R; Murphy, RF; Van den Berg, HW1
Carlsson, J; Malmqvist, M; Nederman, T1
Nissen, E; Tanneberger, S1
Brockman, RW; DuBois, NF; Frye, JL; Shaddix, SC; Shealy, YF1
Martin, DS; Woodcock, TM; Young, CW1
Ensminger, W; Frei, E; Kirkwood, JM; Papathanasopoulos, N; Rosowsky, A1
Martin, D; Nayak, R; Sawyer, R; Spiegelman, S; Stolfi, R1
Damin, LA; Kemeny, NE; Martin, DS; Woodcock, TM; Young, CW1
Hopkins, HA; Looney, WB; Moore, JV1
Martin, DS; Nayak, R; Sawyer, RC; Spiegelman, S; Stolfi, RL1
Gans, JH; Smuckler, EA1
Filov, VA; Reztsova, VV; Stukov, AN1
Holland, JF; Mandel, E; Martin, DS; Ohnuma, T; Roboz, J; Waxman, S1
Henson, E; McClarty, G; Wang, LL1
Komada, Y; Sakai, H; Sakatoku, H; Sakurai, M; Tanaka, S; Xue, HL; Zhang, XL; Zhou, YW1
Bicknell, R; Harris, AL; Moghaddam, A; Patterson, AV; Stratford, IJ; Talbot, DC; Zhang, H1
Andreola, S; Benini, E; Brambilla, C; Daidone, MG; Ferrari, L; Greco, M; Luisi, A; Mastore, M; Silvestrini, R; Veneroni, S1
Aiba, K; Allegra, CJ; Chu, E; Copur, S; Drake, JC1
Hu, JL; Qi, CQ; Su, J; Zhen, YC1
Allegra, CJ; Geoffroy, FJ; Grem, JL; Sinha, B1
Morris, DL; Romani, R1
Alama, A; Camoriano, A; Campora, E; Gardin, G; Meazza, R; Merlini, L; Naso, C; Pronzato, P; Repetto, L; Rosso, R1
Handschumacher, RE; Pizzorno, G; Sun, Z1
Davis, MA; Lawrence, TS; Maybaum, J1
Bamberger, U; Chen, HX; Cheng, YC; Guo, X; Heckel, A1
Heiden, T; Lewin, F; Skog, S; Tribukait, B1
Kajimura, N; Miyazaki, N; Ohkura, H; Okazaki, N1
Bierkens, J; Borremans, B; Falla, N; Schoeters, G; Van Gorp, U1
Abbott, BD; Buckalew, AR; Elstein, KH; Kavlock, RJ; Lau, C; Logsdon, TR; Setzer, W; Zucker, RM1
Baumgart, F; Köpf-Maier, P; Tausch-Treml, R; Ziessow, D1
Horowitz, R; Schwartz, EL; Wadler, S1
Baldini, E; Bevilacqua, G; Collecchi, P; Conte, PF; Giannessi, PG; Naccarato, AG; Passoni, A1
Hickman, JA; Jackman, AL; Potten, CS; Pritchard, DM; Watson, AJ1
Amadori, A; Amadori, D; Amaducci, L; Giunchi, DC; Maltoni, R; Nanni, O; Saragoni, A; Silvestrini, R; Vio, A; Volpi, A1
Ishida, R; Ito, S; Koda, A; Mori, H; Nagai, H; Nakayama, K1
Esaki, T; Fujishima, H; Kondo, T; Masumoto, N; Nakano, S; Niho, Y; Tatsumoto, T1
Elstein, KH; Kavlock, RJ; Lau, C; Mole, ML; Rogers, JM; Setzer, RW; Zucker, RM1
Boisteau, O; Cordel, S; Grégoire, M; Heymann, MF; Le Pendu, J; Meflah, K; Oliver, L1
Peters, GJ; Pinedo, HM; van Groeningen, CJ1
Griffiths, JR; Judson, IR; Leach, MO; McSheehy, PM; Ojugo, AS; Rodrigues, LM; Seymour, MT1
Cao, S; McGuire, JJ; Rustum, YM1
Calvert, H; Hughes, A1
Allegra, CJ; Behan, K; Danenberg, KD; Danenberg, PV; Drake, J; Grem, JL; Monks, A; Nguyen, D; Parr, A; Young, L1
Backus, HH; Bunni, MA; Comijn, L; Jackman, AL; Jansen, G; Mitchell, F; Peters, GJ; Priest, DG; Smid, K; van der Wilt, CL; Veerman, G; Voorn, DA; Wouters, D1
Kojima, T; Miwa, M; Naruse, T1
Drouin, R; Lavoie, J1
FIELD, EO; KRISS, JP; TUNG, LA1
GEISSLER, E1
SALZMAN, NP; SEBRING, ED1
NICHOL, CA; WHITE, PJ1
GOLDE, A; VIGIER, P1
GOODMAN, F1
DUMONT, AE; SOHN, N1
KAPLAN, HS; MARCOVICH, H1
DUBBS, DR; KIT, S; PIEKARSKI, LJ1
DUBBS, DR; KIT, S1
BRUES, AM; MCDONALD, GO; STROUD, AN; SVOBODA, BR1
MILLER, E; SULLIVAN, RD1
BOND, SB; KRISS, JP1
BADER, JP1
KAPLAN, AS1
BENSON, JW; DAMM, H; DESPREZ, JD; KIEHN, CL1
CASSHYAP, P; RAZZELL, WE1
BUSCH, H; SMITH, SJ1
BODMER, WF; GRETHER, S1
MORSE, PA; POTTER, VR1
MOURAD, EB1
EDLIN, G1
BASCH, RS; KARNOFSKY, DA1
D'Costa, SS; Hurwitz, JL1
Ahn, JM; Kim, JH; Lee, HC; Lee, SN1
Antony, S; Gmeiner, WH; Kohlhagen, G; Liao, ZY; Pommier, Y; Sordet, O; Zhang, HL1
Aboagye, E; Pillai, RG; Price, P; Yau, K1
Al-Salabi, MI; Candlish, D; de Koning, HP; Gudin, S; Jarvis, SM; Quashie, NB; Ranford-Cartwright, LC1
Cricca, S; de Bruin, M; Laan, AC; Masterson, AJ; Noordhuis, P; Peters, GJ; Temmink, OH; Turksma, AW1
Clarke, SJ; Hoskins, J; Li, KM; Rivory, LP; Sharma, R1
Bowie, MB; Eaves, CJ; Hoodless, PA; Kent, DG; McCaffrey, L; McKnight, KD1
Cassidy, J; Collie-Duguid, ES; McLeod, HL; Wang, W1
Besier, S; Brade, V; Dehghani, F; Loitsch, S; Saum, SH; Wichelhaus, TA; Zander, J1
Gustafsson, SB; Jacobsson, SO; Jonsson, M; Lindgren, T1
Balzarini, J; Berndsen, SC; Direcks, WG; Lammertsma, AA; Molthoff, CF; Peters, GJ; Proost, N; Spreeuwenberg, MD1
Deng, J; Fazzone, W; LaBonte, MJ; Ladner, RD; Neamati, N; Wilson, PM1
Brody, JR; Costantino, CL; Eshleman, JR; Gallmeier, E; Hucl, T; Kern, SE; van der Heijden, MS; Wikiewicz, AK; Winter, JM; Yeo, CJ; Zhu, H1
Brazowski, E; Eisenthal, A; Eytan, K; Gitstein, G; Greenberg, R; Skornick, Y1
Banerjee, D; Bertino, JR; Blasberg, RG; Cai, S; de Stanchina, E; Kochetkov, T; Moroz, MA; Nair, J; Schwartz, GK; Serganova, I; Shamis, M; Wu, J1
Doseth, B; Kavli, B; Krokan, HE; Pettersen, HS; Slupphaug, G; Svaasand, EK; Vågbø, CB; Visnes, T1
Dingler, FA; Kemmerich, K; Neuberger, MS; Rada, C1
Basílio Janke, EM; Weisz, K1
Abel, G; Barthelmes, J; Dueregger, A; Guggenberger, F; Haunschild, J; Intelmann, D; Klocker, H; Ramoner, R; Sampson, N; Schuh, M; Stecher, G1
Chang, ML; Chen, YC; Chien, RN; Hsu, CW; Lin, CL; Yeh, C; Yeh, CT1
Bešker, N; D'Abramo, M; Gentili, P; Giansanti, L; Gradella Villalva, D; La Bella, A; Leonelli, F; Mancini, G; Petaccia, M1
Dong, Y; Guan, Z; Niu, B; Wang, J; Wang, X; Zhu, Z1
Aboagye, EO; Doblas, S; Döring, C; Faber, C; Fricke, IB; Griffiths, JR; Heinzmann, K; Heller, A; Hermann, S; Honess, DJ; Jacobs, AH; Just, N; Rieder, N; Schäfers, KP; Schelhaas, S; Schneider, R; Sinkus, R; Smith, DM; Wachsmuth, L1
Reigan, P; Warfield, BM1

Reviews

23 review(s) available for fluorouracil and thymidine

ArticleYear
The fluoropyrimidines: biochemical mechanisms and design of clinical trials.
    Cancer chemotherapy and pharmacology, 1978, Volume: 1, Issue:2

    Topics: Antineoplastic Agents; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Metabolism; Methotrexate; Pyrimidines; Thymidine; Thymine

1978
Biochemical modulation of fluorouracil by dipyridamole: preclinical and clinical experience.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3

    Topics: Colonic Neoplasms; Deoxyuridine; Dipyridamole; DNA Damage; DNA, Neoplasm; Drug Interactions; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Methotrexate; Nucleosides; Nucleotides; RNA, Neoplasm; Thymidine; Tumor Cells, Cultured; Uridine Monophosphate

1992
Oncogenic transformation of C3H/10T1/2 Cl 8 mouse embryo fibroblasts by inhibitors of nucleotide metabolism.
    Basic life sciences, 1985, Volume: 31

    Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Cytidine; Deoxycytidine; Deoxyribonucleotides; DNA; Embryo, Mammalian; Fibroblasts; Floxuridine; Fluorouracil; Idoxuridine; Methotrexate; Mice; Mice, Inbred C3H; Mutation; Thymidine; Trifluridine

1985
Role of thymidine in biochemical modulation: a review.
    Cancer research, 1987, Aug-01, Volume: 47, Issue:15

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cytarabine; Deoxycytidine Kinase; DNA Replication; DNA, Neoplasm; Drug Evaluation; Drug Synergism; Fluorouracil; Folic Acid Antagonists; Humans; Interphase; Kinetics; Leukemia; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Nucleic Acid Synthesis Inhibitors; Nucleotides; Phosphonoacetic Acid; RNA, Neoplasm; Species Specificity; Thymidine

1987
Biochemical modulation: application of laboratory models to the clinic.
    Cancer treatment reports, 1986, Volume: 70, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cytarabine; Dose-Response Relationship, Drug; Drug Evaluation; Fluorouracil; Humans; Methotrexate; Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid; Thymidine

1986
The genetic consequences of the Thy- mutation to CHO cells.
    Basic life sciences, 1985, Volume: 31

    Topics: Adenine Phosphoribosyltransferase; Alkylating Agents; Animals; Carbon-Nitrogen Ligases; Cell Line; Cricetinae; Cytarabine; Cytidine Triphosphate; Deoxycytosine Nucleotides; Deoxyribonucleotides; DNA; Drug Resistance; Female; Fluorouracil; Genes; Hypoxanthine Phosphoribosyltransferase; Ligases; Mutation; Ovary; Phenotype; Thymidine; Thymine Nucleotides; Ultraviolet Rays

1985
Bromodeoxyuridine mutagenesis and deoxyribonucleotide pool imbalance in mammalian cells.
    Basic life sciences, 1985, Volume: 31

    Topics: Animals; Base Composition; Bromodeoxyuridine; Cell Line; Cricetinae; Cytarabine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleotides; DNA; Drug Resistance; Fluorouracil; Hydroxyurea; Melanoma; Mutation; Ribonucleotide Reductases; Sister Chromatid Exchange; Thymidine

1985
The cell cycle and the development of pathology in the gastrointestinal tract.
    Pathobiology annual, 1972, Volume: 2

    Topics: Adenine; Animals; Autoradiography; Cell Count; Cell Division; Colon; Digestive System; DNA; Flucytosine; Fluorouracil; Humans; Intestine, Small; Methotrexate; Pentosyltransferases; RNA; Stomach; Thymidine; Thymidine Kinase; Tritium

1972
Obstacles to the improvement of radiotherapy of rectal cancer.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:12

    Topics: Adenocarcinoma; Animals; Cyclophosphamide; Fluorouracil; Humans; Laparotomy; Lymphography; Methods; Neoplasms, Experimental; Prognosis; Rectal Neoplasms; Thymidine; Tritium

1973
Chemotherapy and the life cycle of leukaemic cells. A comparison between the growth characteristics of human acute leukaemia and the murine leukaemia L 1210.
    Folia medica Neerlandica, 1969, Dec-02, Volume: 12, Issue:2

    Topics: Anilides; Animals; Cell Division; Cyclophosphamide; Cytarabine; DNA, Neoplasm; Fluorouracil; Humans; Hydroxyurea; In Vitro Techniques; Leukemia; Leukemia L1210; Leukemia, Lymphoid; Mechlorethamine; Mercaptopurine; Methotrexate; Mice; Mitosis; Nitroso Compounds; Prednisone; Thymidine; Time Factors; Tritium; Vinblastine; Vincristine

1969
[Various aspects of the problem of selectivity in the chemotherapy of cancer].
    Voprosy onkologii, 1969, Volume: 15, Issue:8

    Topics: Animals; Antimetabolites; Antineoplastic Agents; Chemical Phenomena; Chemistry; DNA, Neoplasm; Fluorouracil; Mercaptopurine; Molecular Biology; Neoplasms, Experimental; Nucleotides; Pyridines; Pyrimidines; RNA, Neoplasm; Thymidine; Transferases

1969
The pharmacology of the fluoropyrimidines.
    Pharmacological reviews, 1981, Volume: 33, Issue:1

    Topics: Animals; Chemical Phenomena; Chemistry; Deoxyuracil Nucleotides; Flucytosine; Fluorodeoxyuridylate; Fluorouracil; Fungi; Humans; Kinetics; RNA; Thymidine; Thymidylate Synthase

1981
The target cell determinants of the antitumor actions of 5-FU: does FU incorporation into RNA play a role?
    Cancer treatment reports, 1981, Volume: 65 Suppl 3

    Topics: Animals; DNA, Bacterial; DNA, Neoplasm; Fluorodeoxyuridylate; Fluorouracil; Mice; Neoplasms, Experimental; RNA, Bacterial; RNA, Neoplasm; Thymidine

1981
Thymidine as an anticancer agent, alone or in combination. A biochemical appraisal.
    Cancer chemotherapy and pharmacology, 1982, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents; Azacitidine; Cytarabine; Decitabine; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Neoplasms; Thymidine

1982
Dose-dependent metabolism, therapeutic effect, and toxicity of anticancer drugs in man.
    Drug metabolism reviews, 1983, Volume: 14, Issue:6

    Topics: Alanine; Antineoplastic Agents; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Fluorouracil; Humans; Ifosfamide; Kinetics; Methotrexate; Thymidine

1983
Neurological complications of antineoplastic therapy.
    Acta neurologica Scandinavica. Supplementum, 1984, Volume: 100

    Topics: Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Aspartic Acid; Cisplatin; Cytarabine; Fluorouracil; Humans; Methotrexate; Nervous System Diseases; Phosphonoacetic Acid; Thymidine; Vinblastine; Vincristine

1984
Is there a role for thymidine in cancer chemotherapy?
    Cancer treatment reviews, 1982, Volume: 9, Issue:4

    Topics: Cytarabine; Drug Therapy, Combination; Fluorouracil; Humans; Kinetics; Leukemia; Methotrexate; Neoplasms; Thymidine

1982
Treatment of cultured human colon carcinoma cells with fluorinated pyrimidines.
    Cancer, 1980, Mar-15, Volume: 45, Issue:5 Suppl

    Topics: Cell Line; Cell Survival; Colonic Neoplasms; Culture Media; Drug Evaluation, Preclinical; Fluorouracil; Humans; Tegafur; Thymidine; Uridine

1980
[Metabolic modulation as a method in tumor chemotherapy].
    Die Pharmazie, 1982, Volume: 37, Issue:7

    Topics: Antineoplastic Agents; Cytarabine; Fluorouracil; Humans; Methotrexate; Neoplasms; Tegafur; Thymidine; Uracil

1982
An overview of thymidine.
    Cancer, 1980, Mar-15, Volume: 45, Issue:5 Suppl

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Methylthioinosine; Mice; Neoplasms; Thymidine

1980
Determinants of response to antimetabolites and their modulation by normal purine and pyrimidine metabolites.
    Cancer treatment reports, 1981, Volume: 65 Suppl 3

    Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; DNA, Neoplasm; Fluorodeoxyuridylate; Fluorouracil; Humans; Leukemia L1210; Neoplasms; Neoplasms, Experimental; Thymidine; Thymidylate Synthase; Uridine

1981
Modulation of 5-fluorouracil by interferon: a review of potential cellular targets.
    Medical oncology (Northwood, London, England), 1995, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Combined Modality Therapy; Fluorouracil; Humans; Interferons; Neoplasms; Neovascularization, Pathologic; Thymidine; Thymidine Phosphorylase; Thymidylate Synthase; Tumor Cells, Cultured

1995
Multifunctional role of thymidine phosphorylase in cancer.
    Trends in cancer, 2022, Volume: 8, Issue:6

    Topics: Fluorouracil; Humans; Neoplasms; Neovascularization, Pathologic; Thymidine; Thymidine Phosphorylase

2022

Trials

10 trial(s) available for fluorouracil and thymidine

ArticleYear
Phase I study of thymidine plus 5-fluorouracil infusions in advanced colorectal carcinoma.
    Cancer treatment reports, 1979, Volume: 63, Issue:1

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Middle Aged; Rectal Neoplasms; Thymidine

1979
A clinical trial of biochemical modulation of 5-fluorouracil with N-phosphonoacetyl-L-aspartate and thymidine in advanced gastric and anaplastic colorectal cancer.
    Cancer, 1990, Sep-01, Volume: 66, Issue:5

    Topics: Adult; Aged; Aspartic Acid; Clinical Trials as Topic; Colorectal Neoplasms; Drug Evaluation; Drug Synergism; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Phosphonoacetic Acid; Stomach Neoplasms; Thymidine

1990
A controlled evaluation of recent approaches to biochemical modulation or enhancement of 5-fluorouracil therapy in colorectal carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Levamisole; Male; Middle Aged; Neoplasm Metastasis; Phosphonoacetic Acid; Random Allocation; Rectal Neoplasms; Semustine; Streptozocin; Thymidine; Vincristine

1985
UV protective effects of 5-fluorouracil and thymidine.
    Dermatologica, 1973, Volume: 147, Issue:2

    Topics: Absorption; Candida albicans; Fluorouracil; Humans; Radiation Effects; Radiation-Protective Agents; Skin; Thymidine; Time Factors; Ultraviolet Rays

1973
Cancer chemotherapy. Progress and expectations, 1984.
    Cancer, 1984, Dec-01, Volume: 54, Issue:11 Suppl

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Cytarabine; Drug Resistance; Fluorouracil; Humans; Neoplasms; Thymidine; Time Factors

1984
Current studies of methotrexate and 5-fluorouracil and their interaction in human tumor cells.
    Seminars in oncology, 1983, Volume: 10, Issue:2 Suppl 2

    Topics: Animals; Cells, Cultured; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Leukemia L1210; Methotrexate; Mice; Neoplasm Transplantation; Purines; Random Allocation; Thymidine

1983
An overview of thymidine.
    Cancer, 1980, Mar-15, Volume: 45, Issue:5 Suppl

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Methylthioinosine; Mice; Neoplasms; Thymidine

1980
Changes in biological markers after primary chemotherapy for breast cancers.
    International journal of cancer, 1995, May-04, Volume: 61, Issue:3

    Topics: Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Breast Neoplasms; Cell Cycle; Cell Division; Cyclophosphamide; Diploidy; DNA, Neoplasm; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Mitoxantrone; Neoplasm Staging; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; S Phase; Thymidine; Tumor Suppressor Protein p53

1995
Effects of primary chemotherapy on biological parameters of locally advanced breast cancer.
    Annals of the New York Academy of Sciences, 1996, Apr-30, Volume: 784

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cisplatin; Cyclophosphamide; Epirubicin; Evaluation Studies as Topic; Female; Fluorouracil; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Methotrexate; Middle Aged; Prospective Studies; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptor, IGF Type 1; Thymidine; Treatment Outcome; Tritium

1996
Significant renoprotective effect of telbivudine during preemptive antiviral therapy in advanced liver cancer patients receiving cisplatin-based chemotherapy: a case-control study.
    Scandinavian journal of gastroenterology, 2014, Volume: 49, Issue:12

    Topics: Acute Kidney Injury; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Carcinoma, Hepatocellular; Cisplatin; Female; Fluorouracil; Hepatitis B, Chronic; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Mitomycin; Protective Agents; Telbivudine; Thymidine; Treatment Outcome

2014

Other Studies

319 other study(ies) available for fluorouracil and thymidine

ArticleYear
Synthesis and biological activities of some uronic acids, uronates, uronamides, and urononitriles of pyrimidine nucleosides.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:11

    Topics: Animals; Cell Division; Cells, Cultured; Chick Embryo; Pyrimidine Nucleosides; Sarcoma 180; Simplexvirus; Streptococcus; Structure-Activity Relationship; Substrate Specificity; Thymidine Kinase; Thymidylate Synthase; Uronic Acids; Virus Replication

1978
The effects of 5-fluorouracil and 5-fluorodeoxyuridine used alone and in combination with normal nucleic acid precursors on development of mice in lines selected for low and high expression of Strong's luxoid gene.
    Teratology, 1975, Volume: 11, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Cell Survival; Drug Synergism; Female; Fetal Death; Floxuridine; Fluorouracil; Forelimb; Genes; Hindlimb; Mice; Mutation; Nucleic Acids; Pregnancy; Protein Precursors; Thymidine; Thymine; Tibia; Toes; Uracil

1975
Sensitivity tests of tumors to cytostatic agents. I. Comparative investigations on transplanted tumors in vivo and in vitro.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1975, Volume: 83, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cell Division; Cricetinae; Dactinomycin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Fluorouracil; In Vitro Techniques; Melanoma; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Plasmacytoma; Procarbazine; Rats; Rats, Inbred ACI; Sarcoma 180; Thymidine; Triaziquone; Uridine

1975
Increased urinary excretion of nucleic acid and nicotinamide derivatives by rats after treatment with alkylating agents.
    Chemico-biological interactions, 1975, Volume: 10, Issue:5

    Topics: 2-Acetylaminofluorene; Alkylating Agents; Animals; Benz(a)Anthracenes; Busulfan; Chromatography, Thin Layer; Cytarabine; Deoxycytidine; Dichlorvos; Dimethylnitrosamine; Ethyl Methanesulfonate; Female; Fluorouracil; Hydrocarbons, Brominated; Mechlorethamine; Methylguanidine; Niacinamide; Nitrosourea Compounds; Rats; Thymidine; Uric Acid

1975
Oncogenic transformation of C3H/10T1/2 clone 8 mouse embryo cells by halogenated pyrimidine nucleosides.
    Cancer research, 1976, Volume: 36, Issue:1

    Topics: Animals; Antigens, Viral; Bromodeoxyuridine; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Idoxuridine; Mice; Oncogenic Viruses; Sarcoma, Experimental; Thymidine; Time Factors; Trifluridine

1976
Toxoplasma gondii: characterization of a mutant resistant to 5-fluorodeoxyuridine.
    Experimental parasitology, 1977, Volume: 42, Issue:1

    Topics: Animals; Cell Line; Deoxyuridine; DNA; Drug Resistance; Floxuridine; Fluorouracil; Genes; Mutation; RNA; Thymidine; Toxoplasma; Uridine

1977
[Mechanism of the chromosome damaging effect of ftorafur].
    Genetika, 1977, Volume: 13, Issue:3

    Topics: Animals; Cell Line; Chromosome Aberrations; Chromosomes; Cricetinae; Floxuridine; Fluorouracil; Mitosis; Mutagens; Tegafur; Thymidine

1977
Defective transport of thymidine by cultured cells resistant to 5-bromodeoxyuridine.
    Journal of supramolecular structure, 1977, Volume: 6, Issue:3

    Topics: Biological Transport, Active; Bromodeoxyuridine; Drug Resistance; Floxuridine; Fluorouracil; HeLa Cells; Kinetics; Mutation; Ribonucleosides; Thymidine; Thymidine Kinase

1977
Biochemical aspects of the interactions of the teratogens 5-fluorouracil and 5-fluorodeoxyuridine with normal nucleic acid precursors in mice selected for low and high expression of Strong's luxoid gene.
    Teratology, 1978, Volume: 18, Issue:2

    Topics: Animals; Carbon Radioisotopes; DNA; Embryo, Mammalian; Floxuridine; Fluorouracil; Mice; Mice, Mutant Strains; Nucleic Acid Precursors; RNA; Teratogens; Thymidine

1978
Selectivity of action of 5-FU: biochemical basis.
    Bulletin du cancer, 1979, Volume: 66, Issue:1

    Topics: Animals; Colonic Neoplasms; Drug Resistance; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Leukemia L1210; Mice; Mice, Inbred Strains; Rats; RNA, Neoplasm; Thymidine; Uridine

1979
Distinguishing between membrane transport and intracellular metabolism of fluorodeoxyuridine in Ehrlich ascites tumor cells by application of kinetic and high performance liquid chromatographic techniques.
    The Journal of biological chemistry, 1979, Jun-25, Volume: 254, Issue:12

    Topics: Animals; Biological Transport, Active; Carcinoma, Ehrlich Tumor; Cell Membrane; Chromatography, High Pressure Liquid; Deoxyuridine; Floxuridine; Fluorouracil; Kinetics; Mice; Thymidine; Uridine

1979
Utilization of 3H from deoxyuridine and thymidine for synthesis of DNA and tother macromolecules in various organs of the rat.
    Biochemical pharmacology, 1977, Jan-01, Volume: 26, Issue:1

    Topics: Animals; Bone Marrow; Carcinoma, Hepatocellular; Deoxyuridine; DNA; Fluorouracil; Intestinal Mucosa; Liver; Liver Neoplasms; Rats; Rats, Inbred ACI; RNA; Thymidine; Tritium

1977
Physiological state of human embryonic lung cells affects their response to human cytomegalovirus.
    Journal of virology, 1977, Volume: 23, Issue:1

    Topics: Antigens, Viral; Cell Line; Cytomegalovirus; DNA; DNA, Viral; Fluorouracil; Herpesvirus 1, Suid; Humans; Lung; Simplexvirus; Thymidine; Virus Replication

1977
In vitro incorporation of [3H]TdR in human and murine solid tumours. Influence of 5-fluorouracil and/or hyperbaric oxygen on spatial distribution of labelling.
    Cell and tissue kinetics, 1979, Volume: 12, Issue:6

    Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Fluorouracil; Humans; Mice; Neoplasms; Neoplasms, Experimental; Neoplasms, Germ Cell and Embryonal; Oxygen; Partial Pressure; Sarcoma; Thymidine; Tritium

1979
In vivo enhancement of 5-fluorouracil cytotoxicity to AKR leukemia cells by thymidine in mice.
    Journal of the National Cancer Institute, 1978, Volume: 61, Issue:3

    Topics: Animals; Cell Survival; Colony-Forming Units Assay; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Leukemia L1210; Leukemia, Experimental; Male; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred DBA; Thymidine; Time Factors

1978
Nude mouse models as predictors of chemotherapy in man: thymidine and pyrimidines.
    Bulletin du cancer, 1979, Volume: 66, Issue:1

    Topics: Animals; Antineoplastic Agents; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fluorouracil; Humans; Mice; Mice, Nude; Neoplasms, Experimental; Pyrimidines; Research; Thymidine; Transplantation, Heterologous

1979
A method for continuous drug infusion in unrestrained rats: its application in evaluating the toxicity of 5-fluorouracil/thymidine combinations.
    The Journal of laboratory and clinical medicine, 1979, Volume: 93, Issue:6

    Topics: Animals; Drug Synergism; Female; Fluorouracil; Infusions, Parenteral; Rats; Thymidine

1979
Augmentation by thymidine of the incorporation and distribution of 5-fluorouracil in ribosomal RNA.
    Biochemical and biophysical research communications, 1979, Apr-13, Volume: 87, Issue:3

    Topics: Animals; Fluorouracil; Liver; Liver Regeneration; Male; Orotic Acid; Poly A; Rats; RNA, Ribosomal; Thymidine; Transcription, Genetic

1979
Formation of dUMP-containing DNA by Brij-58 lysed CHO cells.
    FEBS letters, 1979, Sep-01, Volume: 105, Issue:1

    Topics: Animals; Cell Line; Cricetinae; Deoxyuracil Nucleotides; DNA; Female; Fluorouracil; Ovary; Surface-Active Agents; Thymidine; Uracil

1979
Effect of 5-fluorouracil on RNA metabolism in Novikoff hepatoma cells.
    Cancer research, 1979, Volume: 39, Issue:12

    Topics: Animals; Cell Line; Drug Resistance; Fluorouracil; Inosine; Liver Neoplasms, Experimental; Methylation; Rats; Ribonucleotides; RNA, Neoplasm; Thymidine; Thymidylate Synthase

1979
In vitro sensitivity test of stomach cancer tissues by the use of metal grid method.
    The Japanese journal of surgery, 1979, Volume: 9, Issue:4

    Topics: Antineoplastic Agents; Cytarabine; Drug Evaluation, Preclinical; Fluorouracil; Humans; In Vitro Techniques; Methotrexate; Mitomycins; Stomach Neoplasms; Thymidine

1979
Rate of DNA synthesis as an indication of drug toxicity and as a guide for scheduling cancer therapy.
    Cancer treatment reports, 1978, Volume: 62, Issue:5

    Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Lomustine; Methotrexate; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Thymidine

1978
Effect of 5-fluorouracil and thymidine on the transmembrane potential and zeta potential of HeLa cells.
    Cancer research, 1978, Volume: 38, Issue:10

    Topics: Cell Membrane; Fluorouracil; HeLa Cells; Membrane Potentials; Thymidine; Time Factors

1978
The effect of systemic treatment with 5-fluorouracil on the epidermis of the guinea pig.
    Archives of dermatological research, 1978, Sep-28, Volume: 263, Issue:1

    Topics: Animals; Autoradiography; Epidermal Cells; Epidermis; Fluorouracil; Guinea Pigs; Mitosis; Skin; Thymidine

1978
Prevention of antitumor effect of 5-fluorouracil by hypoxanthine.
    Biochemical pharmacology, 1978, Volume: 27, Issue:24

    Topics: Animals; Cell Division; Cell Line; Fluorouracil; Hypoxanthines; Leukemia, Experimental; Mice; Thymidine; Time Factors

1978
In vitro effects of methotrexate, 5-fluorouracil, cyclophosphamide and vincristine sulphate on the metabolism of induced mammary cancers in rats.
    European journal of cancer, 1978, Volume: 14, Issue:12

    Topics: Animals; Cyclophosphamide; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Fluorouracil; In Vitro Techniques; Mammary Neoplasms, Experimental; Methotrexate; Neoplasm Proteins; Rats; Thymidine; Vincristine

1978
The effect of systemic treatment with 5-fluorouracil on the epidermis of the guinea pig.
    Archives of dermatological research, 1978, Volume: 263, Issue:1

    Topics: Animals; Autoradiography; Demecolcine; Epidermis; Fluorouracil; Guinea Pigs; Male; Metaphase; Mitosis; Thymidine; Time Factors; Tritium

1978
Morphogenic effects of halogenated thymidine analogues on Drosophila. VI. Causal analysis of bromodeoxyuridine induced growth lesions.
    Differentiation; research in biological diversity, 1975, Aug-11, Volume: 3, Issue:1-3

    Topics: Animals; Bromodeoxyuridine; DNA; Dose-Response Relationship, Drug; Drosophila melanogaster; Drug Administration Schedule; Fluorouracil; Growth Disorders; Larva; Phenotype; Thymidine; Wings, Animal

1975
In vivo cell synchrony in the L1210 mouse leukaemia studied with 5-fluorouracil or 5-fluorouracil followed by cold thymidine infusion.
    British journal of cancer, 1977, Volume: 35, Issue:5

    Topics: Animals; Cell Division; DNA; Female; Fluorouracil; Leukemia L1210; Mice; Mitotic Index; Neoplasm Transplantation; Thymidine

1977
Kinetic aids to proper chemotherapeutic scheduling: labeled nucleoside incorporation studies in vivo.
    Cancer treatment reports, 1976, Volume: 60, Issue:12

    Topics: Animals; Bone Marrow; Cell Survival; Cyclophosphamide; DNA, Neoplasm; Drug Administration Schedule; Fluorouracil; Granulocytes; Intestinal Mucosa; Kinetics; Lomustine; Male; Melanoma; Methotrexate; Mice; Neoplasms, Experimental; Pyrimidine Nucleosides; Thymidine; Uridine

1976
Effect of cytostatic drugs on nucleic acid synthesis in mouse thymocytes and chick embryo cells.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:3

    Topics: Animals; Antineoplastic Agents; Cells, Cultured; Chick Embryo; Cytarabine; Dactinomycin; Deoxyadenosines; Deoxyuridine; DNA; Fluorouracil; Melphalan; Methotrexate; Mice; Mice, Inbred Strains; Thymidine; Thymus Gland; Triaziquone; Tritium; Uridine; Vinblastine

1975
On the character of the nuclear membrane-associated DNA of HeLa cells.
    Physiological chemistry and physics, 1975, Volume: 7, Issue:2

    Topics: Binding Sites; Carbon Radioisotopes; Cell Fractionation; Cell Nucleus; Centrifugation, Isopycnic; Choline; Chromatography; Deoxycholic Acid; Deoxyribonucleases; DNA; DNA Repair; Fluorouracil; HeLa Cells; Humans; Membranes; Nucleic Acid Denaturation; Peptide Hydrolases; Phospholipases; Ribonucleases; Sodium Chloride; Thymidine

1975
[Effect of 5-fluorouracil and irradiation of the cell kinetics of Walker carcinoma and the small intestine in rats].
    Strahlentherapie, 1975, Volume: 150, Issue:1

    Topics: Animals; Carcinoma 256, Walker; Cell Movement; Epithelial Cells; Epithelium; Fluorouracil; Intestine, Small; Mitosis; Radiation Effects; Rats; Thymidine; Time Factors; Tritium

1975
The effect of cytostatic drugs on the synthesis of DNA in adenocarcinomas of the stomach. An in vitro study.
    Acta chirurgica Scandinavica, 1975, Volume: 141, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Agents; Cells, Cultured; Depression, Chemical; DNA, Neoplasm; Fluorouracil; Humans; In Vitro Techniques; Melphalan; Methotrexate; Stomach Neoplasms; Thymidine; Tritium; Uridine; Vinblastine

1975
The effect of 5-fluorouracil on the mitotic cycle and DNA synthesis in the epithelium of mouse small intestine.
    Folia histochemica et cytochemica, 1975, Volume: 13, Issue:1-2

    Topics: Animals; DNA; Epithelial Cells; Epithelium; Fluorouracil; Intestinal Mucosa; Intestine, Small; Male; Mice; Mitosis; Thymidine

1975
Comparative effects of ftorafur and 5-fluorouracil on DNA synthesis in rat small intestine.
    Life sciences, 1975, Nov-01, Volume: 17, Issue:9

    Topics: Animals; Deoxyuridine; DNA; Fluorouracil; Furans; Intestine, Small; Male; Rats; Thymidine; Thymidylate Synthase

1975
Incorporation of thymidine and iododeoxyuridine into the DNA of mouse tissues.
    Canadian journal of physiology and pharmacology, 1975, Volume: 53, Issue:6

    Topics: Animals; DNA; Female; Fluorouracil; Idoxuridine; Iodine Radioisotopes; Mice; Mice, Inbred Strains; Thymidine; Time Factors

1975
Kinetic alterations induced by 5-fluorouracil in bone marrow, intestinal mucosa, and tumor.
    Cancer research, 1976, Volume: 36, Issue:5

    Topics: Animals; Bone Marrow; Carcinoma, Ehrlich Tumor; Cell Division; Deoxyuridine; DNA; DNA, Neoplasm; Dose-Response Relationship, Drug; Fluorouracil; Intestinal Mucosa; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Thymidine

1976
Chemosensitivity of head and neck cancer with the rapid thymidine incorporation assay and its clinical application.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1992, Volume: 249, Issue:7

    Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Child; Cisplatin; Colonic Neoplasms; DNA, Neoplasm; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Mitomycins; Peplomycin; Remission Induction; Stomach Neoplasms; Thymidine; Tritium; Tumor Cells, Cultured

1992
Time dependence of DNA lesions and growth inhibition by ICI D1694, a new quinazoline antifolate thymidylate synthase inhibitor.
    Cancer research, 1992, Nov-01, Volume: 52, Issue:21

    Topics: Cell Division; Cell Line; DNA; DNA Damage; DNA, Single-Stranded; Fluorouracil; Formyltetrahydrofolates; Methotrexate; Quinazolines; Rhodamines; Thiophenes; Thymidine; Thymidylate Synthase; Time Factors

1992
Thymidine-modulated 5-fluorouracil metabolism in liver and RIF-1 tumors studied by 19F magnetic resonance spectroscopy.
    Magnetic resonance imaging, 1992, Volume: 10, Issue:3

    Topics: Animals; Cell Line; Female; Fibrosarcoma; Fluorouracil; Liver; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C3H; Neoplasms, Radiation-Induced; Thymidine

1992
Effect of folinic acid on fluorouracil activity and expression of thymidylate synthase.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3

    Topics: Animals; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Leucovorin; Mice; Mice, Inbred BALB C; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured; Uridine Monophosphate

1992
Stimulation of 5-fluorouracil metabolic activation by interferon-alpha in human colon carcinoma cells.
    Biochemical and biophysical research communications, 1992, Feb-14, Volume: 182, Issue:3

    Topics: Adenosine; Biotransformation; Cell Line; Colonic Neoplasms; DNA, Neoplasm; Fluorouracil; Humans; Interferon alpha-2; Interferon-alpha; Kinetics; Radioisotope Dilution Technique; Recombinant Proteins; RNA, Neoplasm; Thymidine; Tritium

1992
Azidothymidine and dipyridamole as biochemical response modifiers: synergism with methotrexate and 5-fluorouracil in human colon and pancreatic carcinoma cells.
    Oncology research, 1992, Volume: 4, Issue:2

    Topics: Adenocarcinoma; Cell Division; Cell Line; Cell Survival; Colonic Neoplasms; Dipyridamole; DNA Replication; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; Humans; Methotrexate; Pancreatic Neoplasms; Thymidine; Tumor Stem Cell Assay; Zidovudine

1992
Solid tumour chemotherapy using implantable collagen-poly (HEMA) hydrogel containing 5-fluorouracil.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:1

    Topics: Animals; Collagen; Drug Implants; Female; Fibrosarcoma; Fluorouracil; Hydrogel, Polyethylene Glycol Dimethacrylate; Neoplasm Transplantation; Neoplasms, Experimental; Polyethylene Glycols; Rats; Rats, Inbred Strains; Thymidine

1991
Broad-spectrum antiviral and cytocidal activity of cyclopentenylcytosine, a carbocyclic nucleoside targeted at CTP synthetase.
    Biochemical pharmacology, 1991, Jun-15, Volume: 41, Issue:12

    Topics: Adenosine; Amides; Antiviral Agents; Azauridine; Carbon-Nitrogen Ligases; Cell Division; Cytarabine; Cytidine; Deoxycytidine; Drug Synergism; Fluorouracil; HeLa Cells; Humans; Ligases; Nucleosides; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Thymidine; Tumor Cells, Cultured; Uracil; Virus Replication; Viruses

1991
Comparative DNA strand breakage induced by FUra and FdUrd in human ileocecal adenocarcinoma (HCT-8) cells: relevance to cell growth inhibition.
    Cancer communications, 1991, Volume: 3, Issue:2

    Topics: Adenocarcinoma; Cell Division; Colonic Neoplasms; DNA; DNA Damage; Dose-Response Relationship, Drug; Drug Synergism; Floxuridine; Fluorouracil; Humans; In Vitro Techniques; Leucovorin; Thymidine; Time Factors

1991
AZT: a biochemical response modifier of methotrexate and 5-fluorouracil cytotoxicity in human ovarian and pancreatic carcinoma cells.
    Cancer communications, 1991, Volume: 3, Issue:4

    Topics: Animals; Binding, Competitive; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Female; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Methotrexate; Ovarian Neoplasms; Pancreatic Neoplasms; Rats; Thymidine; Thymidine Kinase; Tumor Cells, Cultured; Zidovudine

1991
Use of the deoxyuridine suppression test to evaluate localized folate deficiency in rat colonic epithelium.
    The American journal of clinical nutrition, 1991, Volume: 53, Issue:6

    Topics: Animals; Cells, Cultured; Colon; Deoxyuridine; DNA; Epithelium; Fluorouracil; Folic Acid; Male; Rats; Rats, Inbred Strains; Thymidine

1991
Abrogation of interferon-induced resistance to interferon-activated major histocompatibility complex-unrestricted killers by treatment of a melanoma cell line with 5-fluorouracil.
    Cancer research, 1991, Jun-15, Volume: 51, Issue:12

    Topics: Adult; Cell Line; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Drug Resistance; Fluorouracil; Humans; Interferon Type I; Killer Cells, Natural; Kinetics; Major Histocompatibility Complex; Melanoma; Recombinant Proteins; Thymidine

1991
Inhibition of rabbit ocular fibroblast proliferation by 5-fluorouracil and cytosine arabinoside.
    Journal of ocular pharmacology, 1991,Spring, Volume: 7, Issue:1

    Topics: Animals; Cell Adhesion; Cell Count; Cell Division; Cell Line; Cells, Cultured; Conjunctiva; Cytarabine; Dose-Response Relationship, Drug; Fibroblasts; Fluorouracil; Humans; Lethal Dose 50; Rabbits; Thymidine

1991
Inhibition of hematopoietic colony-forming cells. Normal bone marrow extract versus transforming growth factor-beta 1.
    Annals of the New York Academy of Sciences, 1991, Volume: 628

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Colony-Forming Units Assay; DNA Replication; Fluorouracil; Hematopoietic Stem Cells; Interleukin-3; Mice; Spleen; Thymidine; Transforming Growth Factor beta

1991
Mechanism of interaction between interferon-gamma and antineoplastic agent on the differentiation of HL-60 promyelocytic cells.
    Experimental hematology, 1990, Volume: 18, Issue:3

    Topics: Cell Differentiation; Cell Division; Cycloheximide; Dactinomycin; Drug Synergism; Fluorouracil; Humans; Interferon-gamma; Leukemia, Promyelocytic, Acute; Thymidine; Tumor Cells, Cultured

1990
Chemosensitivity correlation between the primary tumors and simultaneous metastatic lymph nodes of patients evaluated by DNA synthesis inhibition assay.
    Cancer, 1990, Mar-15, Volume: 65, Issue:6

    Topics: Breast Neoplasms; Carbazilquinone; Cisplatin; Colorectal Neoplasms; DNA, Neoplasm; Doxorubicin; Drug Screening Assays, Antitumor; Esophageal Neoplasms; Fluorouracil; Humans; Jejunal Neoplasms; Mitomycin; Mitomycins; Pancreatic Neoplasms; Stomach Neoplasms; Thymidine

1990
Biochemical modulation of 5-fluoropyrimidine toxicity by dehydroepiandrosterone in human colonic adenocarcinoma cells.
    Cancer communications, 1990, Volume: 2, Issue:6

    Topics: Adenocarcinoma; Carbon Radioisotopes; Colonic Neoplasms; Dehydroepiandrosterone; Fluorouracil; Humans; Interphase; Pyrimidines; Thymidine; Thymidine Monophosphate; Tumor Cells, Cultured; Uracil

1990
Effect of 5-fluorouracil combination therapy on RNA processing in human colonic carcinoma cells.
    British journal of cancer, 1990, Volume: 61, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Nucleolus; Cell Survival; Colonic Neoplasms; Fluorouracil; Humans; RNA Processing, Post-Transcriptional; RNA, Neoplasm; RNA, Ribosomal; Thymidine; Tumor Cells, Cultured

1990
Cellular pharmacology of 5-fluorouracil in a human colon adenocarcinoma cell line selected for thymidine kinase deficiency.
    Biochemical pharmacology, 1990, Jun-01, Volume: 39, Issue:11

    Topics: Adenocarcinoma; Cell Division; Colonic Neoplasms; Cytosol; Fluorouracil; Humans; Kinetics; Thymidine; Thymidine Kinase; Thymidylate Synthase; Tumor Cells, Cultured

1990
Azidothymidine inhibition of thymidine kinase and synergistic cytotoxicity with methotrexate and 5-fluorouracil in rat hepatoma and human colon cancer cells.
    Cancer communications, 1990, Volume: 2, Issue:4

    Topics: Animals; Cell Line; Cell Survival; Colonic Neoplasms; Drug Synergism; Fluorouracil; Humans; Kinetics; Liver Neoplasms, Experimental; Methotrexate; Rats; Thymidine; Thymidine Kinase; Tumor Cells, Cultured; Zidovudine

1990
The cytotoxicity of 5-fluorouracil is due to its incorporation into RNA not its inhibition of thymidylate synthase as evidenced by the use of a mouse cell mutant deficient in thymidylate synthase.
    Japanese journal of cancer research : Gann, 1986, Volume: 77, Issue:7

    Topics: Animals; Cell Survival; Fluorouracil; Mice; Mutation; RNA; Thymidine; Thymidylate Synthase

1986
Modulation of cytotoxicity and metabolism of 5-fluorouracil in two intestine cell lines.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: Cell Cycle; Cell Line; DNA; Drug Synergism; Floxuridine; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Organophosphorus Compounds; Pentosyltransferases; Pyrimidine Phosphorylases; Ribosemonophosphates; RNA; Thymidine; Thymidylate Synthase

1986
Effect of intracellular folate concentration on the modulation of 5-fluorouracil cytotoxicity by the elevation of phosphoribosylpyrophosphate in cultured human KB cells.
    Cancer research, 1987, Dec-15, Volume: 47, Issue:24 Pt 1

    Topics: Adenosine; Carcinoma, Squamous Cell; Cell Survival; Fluorouracil; Folic Acid; Glucose; Humans; KB Cells; Leucovorin; Leukemia, Myeloid, Acute; Methotrexate; Nasopharyngeal Neoplasms; Pentosephosphates; Phosphoribosyl Pyrophosphate; Thymidine

1987
Biochemical and pharmacologic basis for potentiation of 5-fluorouracil action by leucovorin.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:5

    Topics: Animals; Biotransformation; Cell Division; Colonic Neoplasms; DNA; Drug Synergism; Fluorouracil; Folic Acid; Humans; Leucovorin; Leukemia L1210; Mice; RNA; Stomach Neoplasms; Thymidine; Thymidylate Synthase

1987
Dipyridamole potentiates the growth-inhibitory action of methotrexate and 5-fluorouracil in human keratinocytes in vitro.
    The Journal of investigative dermatology, 1989, Volume: 93, Issue:4

    Topics: Cell Division; Dipyridamole; DNA; Drug Synergism; Epidermal Cells; Fluorouracil; Humans; Infant, Newborn; Keratins; Male; Methotrexate; Thymidine

1989
Palatal shelf reorientation in hamster embryos following treatment with 5-fluorouracil.
    Histology and histopathology, 1989, Volume: 4, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; DNA; Embryo, Mammalian; Epithelial Cells; Female; Fluorouracil; Gestational Age; Mesocricetus; Palate; Pregnancy; Thymidine

1989
Isolation of a thymidine kinase negative mutant of Nocardia lactamdurans.
    FEMS microbiology letters, 1989, Volume: 53, Issue:1-2

    Topics: DNA, Bacterial; Floxuridine; Fluorouracil; Mutation; Nocardia; Phenotype; Thymidine; Thymidine Kinase; Thymine

1989
Binucleate cells in the Ehrlich ascites tumor. Autoradiographic labeling.
    Biology of the cell, 1989, Volume: 65, Issue:1

    Topics: Animals; Autoradiography; Carcinoma, Ehrlich Tumor; Cell Nucleus; Female; Fluorouracil; Mice; Mice, Inbred Strains; Mitotic Index; Thymidine; Tritium

1989
Species differences in substrate specificity of pyrimidine nucleoside phosphorylase.
    Journal of surgical oncology, 1989, Volume: 42, Issue:3

    Topics: Animals; Colon; Deoxyuridine; Digestive System; Digestive System Neoplasms; Fluorouracil; Humans; Liver; Mice; Pentosyltransferases; Pyrimidine Phosphorylases; Rats; Rectum; Species Specificity; Stomach; Substrate Specificity; Thymidine; Uridine

1989
Evidence for acyloxymethyl esters of pyrimidine 5'-deoxyribonucleotides as extracellular sources of active 5'-deoxyribonucleotides in cultured cells.
    Biochemical pharmacology, 1989, Oct-01, Volume: 38, Issue:19

    Topics: Animals; Blood Physiological Phenomena; Cells, Cultured; Deoxyuracil Nucleotides; Deoxyuridine; DNA; Esters; Fluorodeoxyuridylate; Fluorouracil; Mice; Thymidine; Thymidine Monophosphate

1989
Precursor-dependent differences in the incorporation of fluorouracil in RNA.
    Molecular pharmacology, 1986, Volume: 29, Issue:6

    Topics: Animals; Cell Survival; Cells, Cultured; Floxuridine; Fluorouracil; Mice; RNA, Neoplasm; Sarcoma, Experimental; Thymidine; Uridine

1986
Modulation of the effects of fluoropyrimidines on toxicity and tumor inhibition in rodents by uridine and thymidine.
    Medical oncology and tumor pharmacotherapy, 1986, Volume: 3, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Female; Floxuridine; Fluorouracil; Leukemia L1210; Lung Neoplasms; Male; Mice; Rats; Rats, Inbred Strains; Sarcoma 180; Thymidine; Uridine

1986
Cytotoxicity of floxuridine and 5-fluorouracil in human T-lymphoblast leukemia cells: enhancement by leucovorin.
    Cancer treatment reports, 1987, Volume: 71, Issue:4

    Topics: Cell Division; Cell Line; Cell Survival; Drug Synergism; Floxuridine; Fluorouracil; Humans; Leucovorin; Leukemia, Lymphoid; T-Lymphocytes; Thymidine

1987
Effects of 5-methyltetrahydrofolate on the activity of fluoropyrimidines against human leukemia (CCRF-CEM) cells.
    Biochemical pharmacology, 1987, Sep-15, Volume: 36, Issue:18

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Floxuridine; Fluorouracil; Humans; Leukemia, Lymphoid; Methionine; Tetrahydrofolates; Thymidine

1987
Increased levels of DNA lesions induced by leucovorin-5-fluoropyrimidine in human colon adenocarcinoma.
    Cancer research, 1988, Aug-01, Volume: 48, Issue:15

    Topics: Adenocarcinoma; Aphidicolin; Cell Line; Cell Survival; Colonic Neoplasms; Diterpenes; DNA; DNA Damage; Drug Synergism; Floxuridine; Fluorouracil; Humans; Leucovorin; Pyrimidines; Thymidine

1988
Catabolism of 5-fluoro-2'-deoxyuridine by isolated rat intestinal epithelial cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1988, Volume: 189, Issue:3

    Topics: Animals; Epithelium; Floxuridine; Fluorouracil; In Vitro Techniques; Intestinal Mucosa; Kinetics; Male; Pentosyltransferases; Pyrimidine Phosphorylases; Rats; Rats, Inbred Strains; Thymidine; Uracil

1988
Trifluorothymidine and 5-fluorouracil: antiproliferative activity in tissue culture.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1987, Volume: 22, Issue:1

    Topics: Animals; Cell Division; Cornea; Culture Techniques; Dose-Response Relationship, Drug; Epithelial Cells; Fibroblasts; Fluorouracil; Humans; Rabbits; Sclera; Thymidine; Trifluridine

1987
Comparative studies on in vitro human tumor clonogenic assay (HTCA) and in vivo nude mouse-isotope assay (NM-IA).
    The Japanese journal of surgery, 1987, Volume: 17, Issue:2

    Topics: Animals; Antineoplastic Agents; Colony-Forming Units Assay; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; In Vitro Techniques; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Mitomycins; Neoplasm Transplantation; Neoplasms; Predictive Value of Tests; Thymidine; Tumor Stem Cell Assay

1987
Comparative study on nude mice isotope assay (NM-IA) and subrenal capsule assay (SRCA) sensitivity tests of anticancer agents.
    The Japanese journal of surgery, 1987, Volume: 17, Issue:2

    Topics: Animals; Antineoplastic Agents; Cisplatin; Colony-Forming Units Assay; Cyclophosphamide; Doxorubicin; Fluorouracil; Kidney; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Mitomycins; Neoplasm Transplantation; Neoplasms, Experimental; Thymidine; Tritium; Tumor Stem Cell Assay

1987
Studies on 18F-labeled pyrimidines III. Biochemical investigation of 18F-labeled pyrimidines and comparison with 3H-deoxythymidine in tumor-bearing rats and mice.
    European journal of nuclear medicine, 1985, Volume: 10, Issue:1-2

    Topics: Animals; Floxuridine; Fluorouracil; Iron Radioisotopes; Liver Neoplasms, Experimental; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Pyrimidines; Radionuclide Imaging; Rats; Thymidine; Tissue Distribution; Tritium; Uridine

1985
Comments on "The molecular basis for the differential sensitivity of B and T lymphocytes to growth inhibition by thymidine and 5-fluorouracil".
    Leukemia research, 1988, Volume: 12, Issue:8

    Topics: B-Lymphocytes; Fluorouracil; Growth Inhibitors; Humans; T-Lymphocytes; Thymidine

1988
Effects of 5-fluorouracil on mitotic index and incorporation of 3H-thymidine into DNA in erythropoietic mouse spleens.
    Acta poloniae pharmaceutica, 1987, Volume: 44, Issue:2

    Topics: Animals; DNA; Erythropoiesis; Fluorouracil; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Mitosis; Mitotic Index; Spleen; Thymidine

1987
Purine nucleosides as cell-specific modulators of 5-fluorouracil metabolism and cytotoxicity.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:12

    Topics: Animals; Cell Division; Cell Line; Fluorouracil; Pentosephosphates; Purine Nucleosides; Ribosemonophosphates; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured

1987
Intratumoral injection of thymidine: enhancement of the antitumor activity and incorporation of 5-fluorouracil into tumor RNA in a murine tumor system.
    Cancer treatment reports, 1986, Volume: 70, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich Tumor; Dose-Response Relationship, Drug; Drug Synergism; Female; Fluorouracil; Injections, Intraperitoneal; Liver; Mice; Proteins; RNA, Neoplasm; Scintillation Counting; Thymidine; Time Factors

1986
Modulation of fluorouracil metabolism and cytotoxicity by nitrothiobenzylinosine.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: Cell Line; Cell Survival; Colonic Neoplasms; Fluorouracil; Humans; Inosine; Thioinosine; Thymidine

1986
Cytokinetic parameters of locally advanced human breast cancer treated with diethylstilbestrol and chemotherapy.
    Basic and applied histochemistry, 1986, Volume: 30, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Cycle; Cyclophosphamide; Diethylstilbestrol; DNA Polymerase II; Doxorubicin; Female; Fluorouracil; Humans; Mitotic Index; Receptors, Estrogen; Thymidine

1986
In vitro degradation of pyrimidine bases: studies of rat liver dihydropyrimidine dehydrogenase.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: Animals; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Kinetics; Liver; Oxidoreductases; Pyrimidines; Rats; Thymidine; Thymine; Uracil; Uridine

1986
Cell kinetics in selection and stratification of patients for adjuvant therapy of breast carcinoma.
    NCI monographs : a publication of the National Cancer Institute, 1986, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Carcinoma in Situ; Cell Cycle; DNA, Neoplasm; Epithelium; Evaluation Studies as Topic; Female; Flow Cytometry; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasm Invasiveness; Neoplasm Staging; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Thymidine; Tritium

1986
Schedule-dependent antitumor and toxic effects of thymidine and 5-fluorouracil in AKR and L1210 leukemias.
    Cancer chemotherapy and pharmacology, 1986, Volume: 18, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Female; Fluorouracil; Hematopoietic Stem Cells; Leukemia L1210; Leukemia, Experimental; Male; Mice; Mice, Inbred Strains; Neoplastic Stem Cells; Thymidine

1986
Dissociation of 5-fluorouracil-induced DNA fragmentation from either its incorporation into DNA or its cytotoxicity in murine T-lymphoma (S-49) cells.
    Cancer research, 1987, Feb-15, Volume: 47, Issue:4

    Topics: Animals; Cell Survival; Chromatography, High Pressure Liquid; Colony-Forming Units Assay; Crotalid Venoms; Deoxyribonuclease I; DNA; Fluorouracil; Lymphoma; Mice; Thymidine; Uridine

1987
Development and characterization of a human colon adenocarcinoma xenograft deficient in thymidine salvage.
    Cancer research, 1987, Apr-15, Volume: 47, Issue:8

    Topics: Adenocarcinoma; Animals; Carcinoembryonic Antigen; Colonic Neoplasms; Fluorouracil; Humans; Isoenzymes; L-Lactate Dehydrogenase; Mice; Mucins; Neoplasm Transplantation; Thymidine; Thymidine Kinase; Transplantation, Heterologous

1987
The molecular basis for the differential sensitivity of B and T lymphocytes to growth inhibition by thymidine and 5-fluorouracil.
    Leukemia research, 1985, Volume: 9, Issue:3

    Topics: B-Lymphocytes; Cells, Cultured; Chromatography, Gel; Chromatography, Ion Exchange; Drug Resistance; Fluorouracil; Growth Inhibitors; Humans; Leukemia; Lymphocytes, Null; Molecular Weight; T-Lymphocytes; Thymidine; Thymidine Phosphorylase

1985
Selective modulation of 5-fluorouracil action in patients with colorectal carcinoma.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1985, Volume: 4, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Humans; Kinetics; Leucovorin; Mice; Mice, Inbred BALB C; Rats; Rectal Neoplasms; Thymidine

1985
Effect of (E)-5-(2-bromovinyl)uracil on the catabolism and antitumor activity of 5-fluorouracil in rats and leukemic mice.
    Cancer research, 1986, Volume: 46, Issue:3

    Topics: Animals; Bromouracil; Dihydrouracil Dehydrogenase (NADP); Drug Synergism; Fluorouracil; Leukemia P388; Leukemia, Experimental; Liver; Metabolic Clearance Rate; Mice; Oxidoreductases; Pyrimidines; Rats; Thymidine; Thymine; Uracil

1986
[Biochemical modulation of 5-FU by thymidine and N-phosphoacetyl-L-aspartate: the relation between 5-FU incorporation into RNA and its cytocidal effect].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:4 Pt 1

    Topics: Animals; Aspartic Acid; Cell Division; Cell Survival; Cells, Cultured; DNA, Neoplasm; Drug Synergism; Female; Fluorouracil; Mammary Neoplasms, Experimental; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; RNA, Neoplasm; Thymidine; Tumor Stem Cell Assay

1986
Phase I evaluation and pharmacokinetic study of weekly iv thymidine and 5-FU in patients with advanced colorectal carcinoma.
    Cancer treatment reports, 1985, Volume: 69, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Fluorouracil; Half-Life; Humans; Infusions, Parenteral; Kinetics; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms; Thymidine

1985
Phase I-II clinical trial of thymidine, 5-FU, and PALA given in combination.
    Cancer treatment reports, 1985, Volume: 69, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic Neoplasms; Drug Evaluation; Fluorouracil; Humans; Middle Aged; Phosphonoacetic Acid; Rectal Neoplasms; Thymidine

1985
Fluorouracil (5-FU) and cytarabine (ara-C) inhibition of corneal epithelial cell and conjunctival fibroblast proliferation.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1985, Volume: 103, Issue:9

    Topics: Animals; Cell Division; Conjunctiva; Cornea; Culture Techniques; Cytarabine; Epithelial Cells; Fibroblasts; Fluorouracil; Rabbits; Thymidine

1985
Effects of uridine and thymidine on the degradation of 5-fluorouracil, uracil, and thymine by rat liver dihydropyrimidine dehydrogenase.
    Cancer research, 1985, Volume: 45, Issue:11 Pt 1

    Topics: Animals; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Kinetics; Liver; Oxidoreductases; Rats; Rats, Inbred Strains; Thymidine; Thymine; Uracil; Uridine

1985
Sequential administration of thymidine, 5-fluorouracil, and PALA. A phase I-II study.
    American journal of clinical oncology, 1985, Volume: 8, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Carcinoma, Bronchogenic; Chromatography, High Pressure Liquid; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Fluorouracil; Half-Life; Humans; Infusions, Parenteral; Middle Aged; Organophosphorus Compounds; Phosphonoacetic Acid; Stomach Neoplasms; Thymidine

1985
Estrogen induced expansion of the growth fraction in receptor negative human breast cancer.
    Journal of steroid biochemistry, 1985, Volume: 23, Issue:6B

    Topics: Breast Neoplasms; Cell Division; Cyclophosphamide; Diethylstilbestrol; DNA Polymerase II; DNA Replication; Doxorubicin; Drug Therapy, Combination; Estrogens; Female; Fluorouracil; Humans; Receptors, Estrogen; Thymidine

1985
Effect of various anticancer agents on DNA polymerase.
    Gan, 1971, Volume: 62, Issue:2

    Topics: Adenosine Triphosphate; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Bone Marrow; Carcinoma, Hepatocellular; Cytosine Nucleotides; Dactinomycin; Deoxyribonucleotides; DNA Nucleotidyltransferases; DNA, Neoplasm; Fluorouracil; Guanosine Triphosphate; Liver; Liver Neoplasms; Liver Regeneration; Mitomycins; Neoplasms, Experimental; Rats; Rifampin; Thymidine; Tritium

1971
Lead-positive nuclear structures and their behavior under the effect of various drugs.
    Journal of ultrastructure research, 1972, Volume: 38, Issue:3

    Topics: Adenosine; Cell Line; Cell Nucleolus; Cell Nucleus; Cycloheximide; Dactinomycin; Deoxyadenosines; Female; Fluorouracil; Histological Techniques; Humans; Lead; Methods; Microscopy, Electron; Pepsin A; Puromycin; Ribonucleases; Staining and Labeling; Thymidine; Trypsin; Uterine Cervical Neoplasms

1972
Inhibition of DNA polymerases and neoplastic cells by selected SH inhibitors.
    Oncology, 1972, Volume: 26, Issue:6

    Topics: Animals; Antineoplastic Agents; Arsenicals; Benzoates; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography, Thin Layer; Colonic Neoplasms; DNA Nucleotidyltransferases; DNA, Neoplasm; Dogs; Fluorouracil; Humans; In Vitro Techniques; Iodoacetates; Leukocytes; Liver; Liver Regeneration; Lung Neoplasms; Mechlorethamine; Mice; Neoplasms; Pancreatic Neoplasms; Reverse Transcriptase Inhibitors; Sulfhydryl Reagents; Thymidine; Thymine Nucleotides; Tritium

1972
A dissection of the inhibitory effects of 5-fluorouracil in Bacillus cereus.
    Chemotherapy, 1973, Volume: 19, Issue:1

    Topics: Bacillus cereus; Carbon Radioisotopes; Cell Count; Cell Division; Cell Nucleus; Cell Survival; Colorimetry; Depression, Chemical; DNA, Bacterial; Fluorouracil; Guanine; Staining and Labeling; Thymidine; Time Factors

1973
Effect of anticancer chemotherapy on the lymphocyte blastoid transformation.
    Gan, 1973, Volume: 64, Issue:5

    Topics: Adult; Aged; Animals; Bleomycin; Cyclophosphamide; Fluorouracil; Gastrointestinal Neoplasms; Humans; Lectins; Lung Neoplasms; Lymphocyte Activation; Middle Aged; Mitomycins; Neoplasms, Experimental; Rabbits; Thymidine; Tritium

1973
[Selective tumour chemotherapy using oncobiograms (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Jan-11, Volume: 99, Issue:2

    Topics: Animals; Antineoplastic Agents; Bleomycin; Cricetinae; Culture Techniques; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Evaluation; Drug Resistance; Fluorouracil; Humans; Methods; Methotrexate; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Procarbazine; Radioisotopes; Rats; Scintillation Counting; Thymidine; Triaziquone; Uridine

1974
[Estimation of tumor sensitivity in vitro. I. Comparative studies with the Jensen sarcoma in vivo and in vitro after 1-hour-incubation].
    Zeitschrift fur Krebsforschung, 1969, Volume: 72, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Autoradiography; Cycloparaffins; Dactinomycin; DNA, Neoplasm; Fluorouracil; In Vitro Techniques; Methods; Methotrexate; Mustard Compounds; Neoplasm Transplantation; Nucleosides; Rats; RNA, Neoplasm; Sarcoma, Experimental; Thymidine; Time Factors; Triaziquone; Tritium; Uridine; Vinblastine

1969
[On the question of preclinical selection of cytostatics in the area of treatment of human tumors].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Carcinoma 256, Walker; Cricetinae; Culture Techniques; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Fluorouracil; Humans; Lung Neoplasms; Methods; Methotrexate; Neoplasms; Neoplasms, Experimental; Radionuclide Imaging; Rats; RNA, Neoplasm; Stimulation, Chemical; Thymidine; Triaziquone; Tritium; Vinblastine; Vincristine

1969
The roles of various biochemical effects produced by 5-fluorouracil in early growth inhibition of Bacillus cereus.
    Biochemical pharmacology, 1974, Oct-01, Volume: 23, Issue:19

    Topics: Bacillus cereus; Carbon Radioisotopes; Centrifugation, Density Gradient; Fluorouracil; Guanine; Ribosomes; RNA, Bacterial; Spectrophotometry, Ultraviolet; Thymidine; Uracil

1974
Errors in DNA replication in bacteria in the presence of a thymidylic acid deficiency.
    Molecular biology, 1974, Volume: 8, Issue:2

    Topics: Bacillus subtilis; Bromouracil; Cell Survival; Deoxyribonucleosides; DNA Replication; Drug Resistance, Microbial; Escherichia coli; Fluorouracil; Glucose; Kinetics; Mathematics; Methyltransferases; Mutagens; Mutation; Probability; Species Specificity; Streptomycin; Thymidine; Thymidylate Synthase; Thymine; Time Factors; Tryptophan

1974
Congenital malformations produced in chickens by fluorinated pyrimidines.
    Archives of pathology, 1966, Volume: 81, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Chick Embryo; Floxuridine; Fluorouracil; Pyrimidines; Thymidine

1966
The effect of nucleic acid synthesis inhibitors on the chlorophyll formation by etiolated bean leaves.
    Biochemical and biophysical research communications, 1966, Jun-13, Volume: 23, Issue:5

    Topics: Azaguanine; Chlorophyll; Dactinomycin; Floxuridine; Fluorouracil; In Vitro Techniques; Mitomycins; Plants, Edible; Thiouracil; Thymidine; Uridine

1966
The response in vitro, of continuous cultures of human lymphoblasts (CCRF-CEM cells) to chemotherapeutic agents.
    Biochemical pharmacology, 1967, Volume: 16, Issue:4

    Topics: Animals; Azaserine; Chloramphenicol; Culture Media; Culture Techniques; Cyclophosphamide; Cytarabine; Dactinomycin; Deoxyuridine; Floxuridine; Fluorouracil; Humans; Hydrocortisone; Lymphocytes; Mechlorethamine; Mercaptopurine; Methotrexate; Mitomycins; Puromycin; Thymidine; Triazines; Vincristine

1967
Determinants of human tumor sensitivity to fluorinated pyrimidine chemotherapy.
    Annals of surgery, 1967, Volume: 166, Issue:4

    Topics: DNA, Neoplasm; Floxuridine; Fluorouracil; Humans; In Vitro Techniques; Ligases; Neoplasm Metastasis; Neoplasms; Phosphotransferases; Thymidine; Thymidine Kinase; Uracil Nucleotides; Uridine

1967
Radiosensitization of brain tumor cells with a thymidine analogue (bromouridine).
    Journal of neurosurgery, 1968, Volume: 28, Issue:6

    Topics: Astrocytoma; Brain Neoplasms; Bromodeoxyuridine; Culture Techniques; DNA; Floxuridine; Fluorouracil; Follow-Up Studies; Glioma; Humans; Meningioma; Methotrexate; Oligodendroglioma; Radiation-Sensitizing Agents; Thymidine

1968
[Comparative in vitro studies with 5-fluorouracil and some of its derivatives].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1969, Volume: 350, Issue:6

    Topics: Acyltransferases; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell-Free System; Depression, Chemical; DNA Nucleotidyltransferases; DNA, Neoplasm; Floxuridine; Fluorine; Fluorouracil; In Vitro Techniques; Leucine; Neoplasm Proteins; Nucleotides; RNA, Neoplasm; Thymidine; Uridine

1969
[Effects of cytostatics and x-rays on nucleic acid metabolism of solid, malignant tumors in vitro].
    Zeitschrift fur Krebsforschung, 1970, Volume: 74, Issue:1

    Topics: Adenine; Animals; Antineoplastic Agents; Carbon Isotopes; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Estriol; Fluorouracil; Formates; Glycine; Hypoxanthines; In Vitro Techniques; Leucine; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasm Proteins; Neoplasms, Experimental; Nucleosides; Orotic Acid; Radiation Effects; RNA, Neoplasm; Testosterone; Thymidine; Triaziquone; Uracil; Uridine

1970
Metabolism of pyrimidines and pyrimidine nucleosides by Salmonella typhimurium.
    Journal of bacteriology, 1972, Volume: 110, Issue:1

    Topics: Aminohydrolases; Cytidine; Cytosine; Deoxyuridine; Floxuridine; Flucytosine; Fluorouracil; Genetics, Microbial; Genotype; Mutation; Nucleosides; Nucleotidyltransferases; Pentosyltransferases; Phosphotransferases; Pyrimidines; Salmonella typhimurium; Thymidine; Uracil; Uracil Nucleotides; Uridine

1972
Incorporation of thymidine after administration of fluorouracil and fluorouridine to adult and embryo mice.
    Research communications in chemical pathology and pharmacology, 1971, Volume: 2, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Cleft Palate; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Fetus; Floxuridine; Fluorine; Fluorouracil; Mice; Mice, Inbred Strains; Pregnancy; Rats; Thymidine; Time Factors; Tritium; Uridine

1971
Incorporation of idoxuridine analogs into corneal herpes simplex virus.
    Annals of ophthalmology, 1972, Volume: 4, Issue:11

    Topics: Animals; Autoradiography; Bromodeoxyuridine; Cornea; DNA, Viral; Epithelium; Floxuridine; Fluorouracil; Herpes Simplex; Idoxuridine; Keratitis, Dendritic; Ophthalmic Solutions; Rabbits; Thymidine; Tritium; Uracil

1972
R factor elimination by inhibitors of thymidylate synthetase (fluorodeoxyuridine and showdomycin) and the occurrence of single strand breaks in plasmid DNA.
    Molecular & general genetics : MGG, 1974, Volume: 133, Issue:2

    Topics: Antibiotics, Antineoplastic; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Extrachromosomal Inheritance; Floxuridine; Fluorouracil; Genetics, Microbial; Methyltransferases; Molecular Biology; Nucleosides; Thymidine; Uracil Nucleotides

1974
Effect of 5-fluorouracil on the multiplication of a virulent virus (pseudorabies) and an oncogenic virus (polyoma).
    Virology, 1967, Volume: 32, Issue:3

    Topics: Autoradiography; Carbon Isotopes; Chromatography; Culture Techniques; DNA; DNA, Viral; Fluorescent Antibody Technique; Fluorouracil; Herpesviridae; Polyomavirus; Thymidine; Tritium

1967
Productive and abortive infections of simian and nonsimian cells with a simian adenovirus SV15. II. Viral biosynthesis and effects of chemical inhibitors.
    Virology, 1968, Volume: 35, Issue:2

    Topics: Adenoviridae; Animals; Antigens; Antimetabolites; Complement Fixation Tests; Cricetinae; Culture Techniques; Cycloheximide; Cytarabine; Cytopathogenic Effect, Viral; Dactinomycin; Defective Viruses; DNA, Viral; Fluorescent Antibody Technique; Fluorouracil; Haplorhini; Helper Viruses; Immunodiffusion; Phenylalanine; Polyomavirus; Thymidine; Tritium; Viral Proteins; Virus Replication

1968
Neurologic surgery.
    Surgery, gynecology & obstetrics, 1970, Volume: 130, Issue:2

    Topics: Animals; Brain Neoplasms; Cats; Dogs; Fluorouracil; Glioblastoma; Humans; Hypothermia, Induced; Laminectomy; Neurosurgery; Spinal Cord Injuries; Thymidine; Warfarin

1970
Cellular DNA synthesis in productive infection with adenoviruses.
    International journal of cancer, 1970, Nov-15, Volume: 6, Issue:3

    Topics: Adenoviridae; Adenoviridae Infections; Animals; Cricetinae; Culture Techniques; DNA; DNA, Viral; Embryo, Mammalian; Fluorouracil; Humans; Hybridization, Genetic; Kidney; Lung; Thymidine; Tritium; Virus Cultivation; Virus Replication

1970
Effect of various inhibitors on the expression of polyoma virus-induced surface antigen in BHK21 cells.
    The Journal of general virology, 1973, Volume: 20, Issue:1

    Topics: Amino Acids; Animals; Antigens, Viral; Autoradiography; Bromodeoxyuridine; Carbon Radioisotopes; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Cycloheximide; Cytarabine; DNA, Viral; Fluorescent Antibody Technique; Fluorouracil; Kidney; Microscopy, Fluorescence; Mitomycins; Polyomavirus; Puromycin; RNA, Viral; Thymidine; Time Factors; Tritium; Viral Proteins

1973
In vitro-in vivo studies on the susceptibility of the solid Yoshida sarcoma to drugs and hyperthermia (42 degrees).
    Cancer research, 1974, Volume: 34, Issue:6

    Topics: Animals; Antineoplastic Agents; Carbon Dioxide; Carbon Radioisotopes; Cell Survival; Cells, Cultured; Cyclophosphamide; Dactinomycin; Fluorouracil; Glycolysis; Hot Temperature; Leucine; Mesylates; Oxygen Consumption; Rats; Sarcoma, Yoshida; Thymidine; Time Factors; Uridine; Vinblastine

1974
The deoxyribonucleoside transport systems of cultured Novikoff rat hepatoma cells.
    Journal of cellular physiology, 1974, Volume: 83, Issue:3

    Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cell Membrane Permeability; Cells, Cultured; Cytochalasin B; Deoxyribonucleosides; Deoxyuridine; Depression, Chemical; Dipyridamole; Fluorouracil; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Rats; Thymidine; Time Factors; Tritium

1974
Incorporation of precursors and inhibitors of nucleic acid synthesis into hepatomas and liver of the rat.
    Cancer research, 1974, Volume: 34, Issue:12

    Topics: Amino Acids; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Fluorouracil; Injections, Intraperitoneal; Injections, Subcutaneous; Liver; Liver Neoplasms; Liver Regeneration; Male; Neoplasm Transplantation; Neoplasms, Experimental; Orotic Acid; Phosphates; Rats; RNA, Neoplasm; Schistosomicides; Thioxanthenes; Thymidine; Time Factors; Transplantation, Homologous; Tritium; Uracil; Uridine

1974
Nucleic acid and protein synthesis and pattern regulation in hydra. II. Effect of inhibition of nucleic acid and protein synthesis on hypostome formation.
    Journal of embryology and experimental morphology, 1969, Volume: 21, Issue:1

    Topics: Animals; Chloramphenicol; Cnidaria; Cytosine; Dactinomycin; DNA; Fluorouracil; Hydroxyurea; Morphogenesis; Protein Biosynthesis; RNA; RNA, Messenger; Thymidine; Transplantation; Tritium; Uridine

1969
Inhibitory effects and metabolism of 5-fluoropyrimidine derivatives in pneumococcus.
    Journal of bacteriology, 1971, Volume: 106, Issue:2

    Topics: Aluminum; Autoradiography; Bacterial Proteins; Bacteriological Techniques; Carbon Isotopes; Cell-Free System; Chemical Precipitation; Chromatography, Ion Exchange; Chromatography, Thin Layer; Colorimetry; Culture Media; Cytosine; DNA, Bacterial; Filtration; Floxuridine; Fluorouracil; Freezing; Microscopy, Phase-Contrast; Nucleotidyltransferases; Oxides; Pyrimidinones; RNA, Bacterial; Streptococcus pneumoniae; Thymidine; Trichloroacetic Acid

1971
The effect of pre-inhibition of DNA synthesis in continuous human amniotic cell culture (strain FL) on adenovirus type 5 reproduction.
    Acta virologica, 1969, Volume: 13, Issue:5

    Topics: Adenoviridae; Aminopterin; Amnion; Animals; Antigens; Autoradiography; Cell Line; Cell Nucleus; Cells, Cultured; DNA; Floxuridine; Fluorescent Antibody Technique; Fluorouracil; Humans; Immune Sera; Rabbits; Radiation Effects; Thymidine; Time Factors; Tritium; Ultraviolet Rays; Virus Replication

1969
The effect of heparin on the cytotoxicity and uptake of anti-neoplastic drugs in cultured Burkitt lymphoma cells.
    Cancer research, 1974, Volume: 34, Issue:12

    Topics: Burkitt Lymphoma; Cell Division; Cell Survival; Cells, Cultured; DNA, Neoplasm; Fluorouracil; Heparin; Humans; Mechlorethamine; Mercaptopurine; Methotrexate; Thymidine; Time Factors; Tritium

1974
In vitro estimate of sensitivity of individual human tumors to antitumor agents.
    Oncology, 1974, Volume: 30, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arsenicals; Benzoates; Breast Neoplasms; Carbon Radioisotopes; Carcinoma; Carcinoma, Ehrlich Tumor; Cattle; Depression, Chemical; DNA, Neoplasm; Female; Fluorouracil; Humans; In Vitro Techniques; Iodoacetates; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Lymphoma, Non-Hodgkin; Mechlorethamine; Methotrexate; Mice; Neoplasms; Phenylalanine; Succinate Dehydrogenase; Thymidine; Tritium

1974
An anomalous effect of hydroxyurea and visible light on nucleic acids of a photoreactivating mammalian cell Potorous tridactylis.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1972, Volume: 21, Issue:1

    Topics: Animals; Carbon Isotopes; Cells, Cultured; Deoxyribonucleosides; Depression, Chemical; DNA; Fluorouracil; Hydroxyurea; In Vitro Techniques; L Cells; Light; Marsupialia; Radiation Effects; Radiobiology; RNA; Thymidine; Tritium; Uridine

1972
Changes in the deoxyribonucleoside triphosphate pools of mouse 5178Y lymphoma cells following exposure to methotrexate or 5-fluorouracil.
    Cancer research, 1973, Volume: 33, Issue:12

    Topics: Adenosine Triphosphate; Animals; Cell Line; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyribonucleotides; Deoxyuridine; DNA, Neoplasm; Fluorouracil; Guanosine; Leukemia, Experimental; Leukemia, Lymphoid; Methotrexate; Mice; Phosphates; Thymidine; Tritium

1973
Degree of participation of exogenous thymidine in the overall deoxyribonucleic acid synthesis in Escherichia coli.
    Journal of bacteriology, 1972, Volume: 110, Issue:2

    Topics: Amino Acids; Culture Media; Deoxyribonucleotides; DNA, Bacterial; Escherichia coli; Fluorouracil; Genetics, Microbial; Mutation; Pentosyltransferases; Temperature; Thymidine; Tritium

1972
Genetic and physiological factors relating to excision-repair in Escherichia coli.
    The Johns Hopkins medical journal, 1972, Volume: 1

    Topics: Cell Survival; Coliphages; Deoxyribonucleases; DNA Nucleotidyltransferases; DNA Repair; DNA, Bacterial; DNA, Viral; Escherichia coli; Fluorouracil; Molecular Weight; Mutation; Nucleic Acid Denaturation; Pyrimidines; Radiation Effects; Thymidine; Thymine; Time Factors; Tritium; Ultraviolet Rays

1972
Regulation of early mRNA synthesis in bacteriophage T4-infected bacteria: dependence on bacteriophage-specific protein synthesis.
    Journal of virology, 1973, Volume: 12, Issue:1

    Topics: Carbon Isotopes; Chloramphenicol; Chromatography, Thin Layer; Coliphages; DNA Viruses; DNA, Viral; Escherichia coli; Fluorouracil; Mutation; Ribonucleotides; RNA, Messenger; Temperature; Thymidine; Time Factors; Transcription, Genetic; Tritium; Uracil; Viral Proteins

1973
Does 5-fluorouracil cause catabolite repression?
    FEBS letters, 1973, Sep-01, Volume: 35, Issue:1

    Topics: Enzyme Induction; Enzyme Repression; Escherichia coli; Fluorouracil; Galactosidases; Genetics, Microbial; Glucose; Kinetics; Lyases; Mutation; Spectrophotometry, Ultraviolet; Thymidine; Tryptophanase

1973
Morphogenic effects of halogenated thymidine analogs on Drosophila. II. Incorporation of 5 -bromodeoxyuridine into DNA.
    Mutation research, 1972, Volume: 14, Issue:1

    Topics: Autoradiography; Bromodeoxyuridine; Cell Nucleus; Centrifugation, Density Gradient; Densitometry; DNA; Drosophila melanogaster; Drug Interactions; Fluorouracil; Germ Cells; Larva; Thymidine; Tritium; Ultracentrifugation

1972
Incubation of surviving sections of ovarian tumours as a method of testing their sensitivity to cytostatics.
    Neoplasma, 1972, Volume: 19, Issue:4

    Topics: Culture Techniques; DNA, Neoplasm; Female; Fluorouracil; Humans; Melphalan; Nitrogen Mustard Compounds; Ovarian Neoplasms; Parathion; Thiotepa; Thymidine; Tritium

1972
Effects of 60 Co gamma radiation on the distribution, catabolism and incorporation of 125 I-5-iodo-2'-deoxyuridine into intestinal and splenic deoxyribonucleic acid in mice.
    Acta radiologica: therapy, physics, biology, 1972, Volume: 11, Issue:6

    Topics: Animals; Ascitic Fluid; Chromatography, Thin Layer; Cobalt Isotopes; DNA; DNA Replication; Fluorouracil; Idoxuridine; Intestine, Small; Iodine Isotopes; Male; Mice; Radiation Effects; Spleen; Thymidine

1972
DNA synthesis outside the replication phase. Report II. An autoradiographic study of H3-thymidine incorporation into the nuclei of PHA-stimulated human lymphocytes during the G1 period.
    Soviet genetics, 1972, Volume: 8, Issue:1

    Topics: Autoradiography; Cell Nucleus; Chromosome Aberrations; Colchicine; DNA; DNA Replication; Fluorouracil; Genotype; Humans; In Vitro Techniques; Lectins; Lymphocyte Activation; Lymphocytes; Mitosis; Thymidine; Tritium

1972
Determination of therapeutic index of drugs by in vitro sensitivity tests using human host and tumor cell suspensions.
    Cancer chemotherapy reports, 1973, Volume: 57, Issue:1

    Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Fluorouracil; Humans; In Vitro Techniques; Methotrexate; Neoplasms; Penicillamine; Thymidine; Time Factors; Tritium

1973
The role of thymidylate synthetase inhibitors in bromodeoxyuridine-induced neoplasia in Drosophila.
    Cancer research, 1973, Volume: 33, Issue:11

    Topics: Animals; Bromodeoxyuridine; Centrifugation, Density Gradient; DNA; Drosophila; Fluorine; Fluorouracil; Idoxuridine; Larva; Methotrexate; Methyltransferases; Neoplasms, Experimental; Thymidine; Thymidylate Synthase; Tritium

1973
Age cohort variation of tumor cells.
    Radiology, 1973, Volume: 109, Issue:1

    Topics: Animals; Cell Division; Disease Models, Animal; DNA, Neoplasm; Fluorouracil; Hydroxyurea; Lymphoma; Mice; Mitosis; Models, Biological; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; RNA, Neoplasm; Thymidine; Time Factors; Tritium

1973
DNA synthesis outside the replication phase. Report I. Cytogenetic analysis of the action of DNA-synthesis inhibitors on human lymphocytes in vitro as it relates to the functional state of the genome.
    Soviet genetics, 1974, Mar-01, Volume: 7, Issue:12

    Topics: Autoradiography; Cell Division; Chromosome Aberrations; Dactinomycin; DNA; DNA Replication; Drug Interactions; Fluorouracil; Genotype; Humans; In Vitro Techniques; Lectins; Lymphocytes; Thymidine; Transcription, Genetic; Tritium; Uracil Mustard

1974
Synchronization of human tissues and its consequences for cancer therapy in ENT. Cell kinetic and clinical studies.
    Advances in oto-rhino-laryngology, 1974, Volume: 21

    Topics: Aged; Animals; Carcinoma; Carcinoma, Squamous Cell; Cell Division; DNA Replication; DNA, Neoplasm; Ear Neoplasms; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Mice; Middle Aged; Mitosis; Nasopharyngeal Neoplasms; Neoplasms, Experimental; Skin Neoplasms; Thymidine; Tritium

1974
Repair replication induced by 3H incorporated into HeLa DNA.
    Mutation research, 1974, Volume: 22, Issue:2

    Topics: Bromouracil; Centrifugation, Density Gradient; Culture Media; DNA Repair; DNA Replication; DNA, Neoplasm; Fluorouracil; HeLa Cells; Humans; In Vitro Techniques; Iodine Radioisotopes; Thymidine; Tritium; Uracil

1974
Inhibition by 6-aminothymine of the degradation of nucleosides (5-iododeoxyuridine, thymidine) and pyrimidine bases (5-iodouracil, uracil and 5-fluorouracil) in vivo.
    Acta biologica et medica Germanica, 1974, Volume: 32, Issue:5

    Topics: Amines; Animals; Antimetabolites; Bone Marrow; Chromatography; DNA; Fluorouracil; Idoxuridine; Intestinal Mucosa; Iodine Radioisotopes; Male; Mice; Nucleosides; Pentosyltransferases; Rabbits; Spleen; Thymidine; Thymine; Thymus Gland; Uracil

1974
The effects of cytostatic drugs on transplanted tumours. An investigation of the correlation between in vivo and in vitro results.
    Archiv fur Geschwulstforschung, 1974, Volume: 43, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cricetinae; Cytarabine; Daunorubicin; Fluorouracil; Melanoma; Methotrexate; Mice; Neoplasm Transplantation; Plasmacytoma; Procarbazine; Rats; Thymidine; Tritium; Uridine

1974
Androgen-induced sexual differentiation of the brain is blocked by inhibitors of DNA and RNA synthesis.
    Nature, 1974, Jan-11, Volume: 247, Issue:5436

    Topics: Animals; Animals, Newborn; Brain; Dactinomycin; Depression, Chemical; DNA; Estrus; Female; Fluorouracil; Gonadotropins; Hydroxyurea; Hypothalamus; Mycotoxins; Organ Size; Ovary; Ovulation; Pregnancy; Protein Biosynthesis; Puromycin; Rats; RNA; Sex Factors; Testosterone; Thymidine; Tritium

1974
Regulation of early RNA synthesis in bacteriophage T4-infected Escherichia coli cells.
    Journal of molecular biology, 1970, Nov-14, Volume: 53, Issue:3

    Topics: Carbon Isotopes; Coliphages; Escherichia coli; Fluorouracil; Kinetics; Leucine; Mutation; RNA, Messenger; RNA, Viral; Temperature; Thymidine; Tritium; Uridine

1970
Role of pyridine nucleotides in 5-fluorouracil-mediated reactivation of ultraviolet radiation damage.
    Journal of bacteriology, 1971, Volume: 106, Issue:3

    Topics: Centrifugation, Density Gradient; Coliphages; Escherichia coli; Fluorouracil; Nucleotides; Oxygen Consumption; Pyridines; Radiation Effects; Spectrophotometry; Sucrose; Thymidine; Tritium; Ultraviolet Rays

1971
Properties of the DNA-delay mutants of bacteriophage T4.
    Virology, 1971, Volume: 46, Issue:3

    Topics: Aniline Compounds; Carbon Isotopes; Centrifugation, Density Gradient; Cesium; Chlorides; Coliphages; DNA Replication; DNA, Bacterial; DNA, Viral; Escherichia coli; Fluorouracil; Genes, Recessive; Genetic Complementation Test; Genetics, Microbial; Leucine; Muramidase; Mutation; Nitrogen Isotopes; RNA, Messenger; Thymidine; Time Factors; Tritium; Uracil; Viral Proteins; Virus Replication

1971
Dissociation of cellular functions in Bacillus cereus by 5-fluorouracil.
    Journal of bacteriology, 1966, Volume: 91, Issue:2

    Topics: Adenine; Amino Acids; Bacillus cereus; Bacterial Proteins; Carbon Isotopes; Cell Wall; DNA, Bacterial; Fluorouracil; In Vitro Techniques; Penicillinase; RNA, Bacterial; Thymidine; Tritium; Uracil

1966
Comparative effects of 5-fluorouracil on strains of Bacillus megaterium.
    Journal of bacteriology, 1964, Volume: 87, Issue:5

    Topics: Bacillus megaterium; Bacterial Proteins; Bacteriolysis; DNA, Bacterial; Drug Resistance, Microbial; Fluorouracil; RNA, Bacterial; Thymidine; Uridine

1964
Synthesis and biological activity of dinucleoside phosphates containing 5-fluorouracil residues.
    Journal of medicinal chemistry, 1966, Volume: 9, Issue:6

    Topics: Cell Membrane Permeability; Chemistry, Organic; Chromatography, Paper; Electrophoresis; Enterococcus faecalis; Fluorouracil; Organic Chemistry Phenomena; Spectrophotometry; Thymidine; Uridine

1966
Properties of 5-fluorouracil-containing ribonucleic acid and ribosomes from Bacillus subtilis.
    Journal of bacteriology, 1968, Volume: 96, Issue:2

    Topics: Amino Acids; Bacillus subtilis; Centrifugation, Density Gradient; Chromatography; Fluorouracil; Molecular Biology; Nucleic Acid Denaturation; Phosphates; Phosphorus Isotopes; Ribosomes; RNA, Bacterial; Thymidine; Tritium

1968
5-mercaptodeoxyuridine--its enzymatic synthesis and mode of action in microbiological systems.
    Biochemical pharmacology, 1969, Volume: 18, Issue:2

    Topics: Biological Assay; Cell-Free System; Chromatography, Ion Exchange; Drug Synergism; Enterococcus faecalis; Fluorouracil; Lactobacillus; Spectrum Analysis; Thymidine; Transferases; Ultraviolet Rays; Uridine

1969
Requirement of cellular synthesis for Kilham rat virus replication.
    Virology, 1970, Volume: 42, Issue:4

    Topics: Animals; Autoradiography; Culture Techniques; DNA; Fluorescent Antibody Technique; Fluorouracil; Herpesviridae; Leucine; Radiation Effects; Rats; Species Specificity; Thymidine; Tritium; Ultraviolet Rays; Uridine; Virus Cultivation; Virus Replication; Viruses, Unclassified

1970
[Effect of thiophosphamide and 5-fluorouracil on the incorporation of H 3-thymidine into DNA of surviving ovarian cancer sections].
    Farmakologiia i toksikologiia, 1971, Volume: 34, Issue:2

    Topics: Culture Techniques; Depression, Chemical; DNA, Neoplasm; Female; Fluorouracil; Humans; Ovarian Neoplasms; Temperature; Thiotepa; Thymidine; Time Factors; Tritium

1971
Morphogenic effects of halogenated thymidine analogs on Drosophila. 3. 5-Iododeoxyuridine.
    Experientia, 1972, Mar-15, Volume: 28, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Centrifugation, Density Gradient; Deoxyuridine; DNA; Drosophila; Fluorouracil; Larva; Thymidine; Tritium

1972
Endotoxin-induced sensitivity of hematopoietic stem cells to chemotherapeutic agents.
    Series haematologica (1968), 1972, Volume: 5, Issue:2

    Topics: Animals; Biological Assay; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cesium Isotopes; Culture Media; Cyclophosphamide; Cytarabine; Dactinomycin; Depression, Chemical; Endotoxins; Female; Fluorouracil; Hematopoietic Stem Cells; Mice; Radiation Effects; Spleen; Stimulation, Chemical; Thymidine; Tritium; Vinblastine

1972
Role of catabolism in pyrimidine utilization for nucleic acid synthesis in vivo.
    Cancer research, 1972, Volume: 32, Issue:2

    Topics: Animals; Azo Compounds; Dactinomycin; Depression, Chemical; DNA; DNA, Neoplasm; Fluorouracil; Intestine, Small; Iodine Isotopes; Leukemia, Experimental; Liver; Male; Nucleosides; Oxidoreductases; Pyrimidines; Rats; RNA; RNA, Neoplasm; Spleen; Thymidine; Thymine; Tritium; Uracil

1972
Response of DNA thymine synthesis in human tumor and normal tissue to 5-fluorouracil.
    Cancer research, 1972, Volume: 32, Issue:1

    Topics: Breast Neoplasms; Carbon Isotopes; Chromatography, Paper; Colon; Colonic Neoplasms; Depression, Chemical; DNA; DNA, Neoplasm; Female; Fluorouracil; Formates; Humans; In Vitro Techniques; Lung Neoplasms; Methyltransferases; Ovarian Neoplasms; Serine; Thymidine; Thymine; Thymine Nucleotides; Tritium; Uracil Nucleotides

1972
Inhibition of cell dcivision and denervation hypersensitivity in skeletal muscle.
    The Journal of physiology, 1972, Volume: 226, Issue:2

    Topics: Acetylcholine; Animals; Fluorouracil; Hindlimb; Methotrexate; Mitosis; Muscle Contraction; Muscle Denervation; Muscles; Rats; Receptors, Drug; Thymidine; Tritium; Vincristine

1972
Cytotoxic penetration and concentration in human malignant tumours.
    The British journal of surgery, 1969, Volume: 56, Issue:10

    Topics: Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Intestinal Neoplasms; Kidney Neoplasms; Neoplasms; Rectal Neoplasms; Thymidine; Tritium

1969
[The modification of the cell division rhythm in human tumors].
    Archiv fur klinische und experimentelle Ohren- Nasen- und Kehlkopfheilkunde, 1969, Volume: 193, Issue:2

    Topics: Adult; Aged; Autoradiography; Biopsy; Cell Division; Depression, Chemical; DNA, Neoplasm; Ear Neoplasms; Female; Fluorouracil; Humans; Male; Mandibular Neoplasms; Maxillary Neoplasms; Middle Aged; Neoplasms; Thymidine; Tongue Neoplasms; Tonsillar Neoplasms; Tritium

1969
The effect of 5-fluorouracil on DNA-thymine synthesis in human tumors.
    Cancer research, 1969, Volume: 29, Issue:12

    Topics: Carbon Isotopes; DNA, Neoplasm; Fluorouracil; Formates; Humans; Neoplasms; Thymidine; Thymine; Tritium

1969
A new paper chromatography solvent system resolving pyrimidine-pyrimidine riboside-pyrimidine deoxyriboside mixtures.
    Analytical biochemistry, 1969, Volume: 30, Issue:3

    Topics: Adenine Nucleotides; Animals; Carcinoma, Ehrlich Tumor; Chromatography, Paper; Culture Techniques; Cytosine Nucleotides; DNA; Fluorouracil; Guanine Nucleotides; Methods; Nucleosides; Pyrimidines; Solvents; Spectrophotometry; Thymidine; Thymine; Ultraviolet Rays; Uracil Nucleotides

1969
Metabolism of uracil and 5-fluorouracil in P388 murine leukemia cells.
    Molecular pharmacology, 1969, Volume: 5, Issue:5

    Topics: Animals; Carbon Isotopes; Cell Line; Cell-Free System; Culture Techniques; Fluorouracil; Leukemia, Experimental; Nucleosides; Nucleotides; Phosphotransferases; Pyrimidines; RNA; Thymidine; Transferases; Uracil; Uridine

1969
[Disturbances of development and differentiation induced in the amphibian embryo by 5-fluorouracil. (Histological and histoautoradiographic examinations)].
    Beitrage zur pathologischen Anatomie und zur allgemeinen Pathologie, 1970, Volume: 140, Issue:4

    Topics: Abnormalities, Drug-Induced; Amphibians; Animals; Anura; Autoradiography; Brain; Cell Nucleus; DNA; Eye; Fluorouracil; Germ Layers; Karyometry; Larva; Spinal Cord; Thymidine; Tritium

1970
Potential anticancer agents. VI. 5-Substituted pyrimidine-6-carboxaldehydes.
    Journal of pharmaceutical sciences, 1970, Volume: 59, Issue:11

    Topics: Aldehydes; Animals; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chemical Phenomena; Chemistry; DNA, Neoplasm; Fluorouracil; Formates; Mice; Orotic Acid; Phenylalanine; Protein Biosynthesis; Pyrimidines; RNA, Neoplasm; Thymidine; Tritium

1970
The relation of thymidine labeling index in human tumors in vitro to the effectiveness of 5-fluorouracil chemotherapy.
    Cancer research, 1971, Volume: 31, Issue:4

    Topics: Autoradiography; Fluorouracil; Humans; In Vitro Techniques; Methods; Neoplasms; Thymidine; Tritium

1971
[Indication for antineoplastic agents (using 3H-thymidine)].
    Saishin igaku. Modern medicine, 1971, Volume: 26, Issue:5

    Topics: Antineoplastic Agents; Culture Techniques; Depression, Chemical; DNA, Neoplasm; Fluorouracil; Humans; Methotrexate; Mitomycins; Stomach Neoplasms; Thymidine; Tritium; Vinblastine

1971
[On the biochemical causes of the cytostatic effect of glyceraldehyde].
    Acta biologica et medica Germanica, 1967, Volume: 19, Issue:1

    Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell-Free System; Fluorouracil; Glyceraldehyde; Glycine; Histocytochemistry; Mice; Nucleic Acids; Phenylalanine; Phosphates; Phospholipids; Phosphorus Isotopes; Protein Biosynthesis; Ribosomes; RNA, Messenger; Thymidine; Tritium; Uracil Nucleotides

1967
Studies on the mechanism of action of progesterone in regulation of the synthesis of specific protein.
    The Journal of clinical investigation, 1968, Volume: 47, Issue:3

    Topics: Amino Acids; Animals; Chickens; Colchicine; Culture Techniques; Cycloheximide; Dactinomycin; Diethylstilbestrol; Estrogens; Female; Fluorouracil; Hydroxyurea; Mitosis; Muramidase; Ovalbumin; Oviducts; Progesterone; Protein Biosynthesis; RNA; RNA Nucleotidyltransferases; Thymidine; Tritium; Uridine

1968
Fluorinated pyrimidine aldehydes. Inhibition of nucleic acid and protein biosynthesis in Ehrlich ascites carcinoma cells in vitro.
    Journal of medicinal chemistry, 1968, Volume: 11, Issue:3

    Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography, Ion Exchange; Chromatography, Thin Layer; DNA; Female; Fluorine; Fluorouracil; Formates; Glycine; In Vitro Techniques; Mice; Orotic Acid; Phenylalanine; Protein Biosynthesis; Purines; Pyrimidines; RNA; Thymidine; Tritium

1968
On the mechanism of the lethal action of 5-fluorouracil on mouse L cells.
    Cancer research, 1968, Volume: 28, Issue:10

    Topics: Dialysis; Fibroblasts; Fluorouracil; In Vitro Techniques; L Cells; Thymidine; Time Factors; Uridine

1968
Transplacental passage of nucleotides, nucleosides, and bases.
    American journal of obstetrics and gynecology, 1968, Dec-15, Volume: 102, Issue:8

    Topics: Alkalies; Animals; Carbon Isotopes; Colchicine; Female; Fetus; Fluorouracil; Injections, Intraperitoneal; Injections, Intravenous; Liver; Maternal-Fetal Exchange; Nucleosides; Nucleotides; Orotic Acid; Placenta; Pregnancy; Purines; Pyrimidines; Radiometry; Rats; RNA; Solubility; Thymidine; Time Factors; Uracil Nucleotides; Uridine

1968
[5'-desoxy-5'-fluorothymidine, a new inhibitor of the DNA synthesis].
    Acta biologica et medica Germanica, 1968, Volume: 20, Issue:3

    Topics: Animals; Carcinoma, Ehrlich Tumor; Colorimetry; Depression, Chemical; DNA, Neoplasm; Fluorouracil; Mercaptopurine; Phosphates; Phosphorus Isotopes; RNA, Neoplasm; Spectrum Analysis; Thymidine; Triazines; Tritium; Uracil

1968
Initiation and suppression of apical hairs of Fucus embryos Fucus embryos.
    Developmental biology, 1969, Volume: 19, Issue:5

    Topics: Cell Differentiation; Eukaryota; Fluorouracil; Hair; In Vitro Techniques; Thymidine; Time Factors; Uracil

1969
Mechanism of pyrimethamine-induced megaloblastosis in human bone marrow.
    The New England journal of medicine, 1969, Jun-12, Volume: 280, Issue:24

    Topics: Anemia, Macrocytic; Bone Marrow; Bone Marrow Diseases; Chorioretinitis; Culture Techniques; Deoxyuridine; DNA; Erythrocytes; Female; Fluorouracil; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Middle Aged; Nucleotides; Oxidation-Reduction; Pyrimethamine; Thymidine; Tritium

1969
Relation of thymidine index to pulmonary tumor response in mice receiving urethan and other carcinogens.
    Cancer research, 1969, Volume: 29, Issue:5

    Topics: Animals; Autoradiography; Carbamates; Carcinogens; Cytarabine; Dactinomycin; DNA; Fluorouracil; Injections, Intraperitoneal; Injections, Subcutaneous; Lung; Lung Neoplasms; Male; Mechlorethamine; Methylcholanthrene; Mice; Neoplasms, Experimental; Puromycin; Thymidine; Tritium; Urethane

1969
Influence of antiblastic agents applied either in vivo or in vitro on human lymphocyte transformation in cell culture.
    Blut, 1969, Volume: 19, Issue:1

    Topics: Antineoplastic Agents; Autoradiography; Colchicine; Culture Techniques; Cyclophosphamide; Daunorubicin; Fluorouracil; Humans; Hydrazines; Lectins; Lymphocyte Activation; Lymphocytes; Mechlorethamine; Prednisolone; Radiation Effects; Thymidine; Tritium; Uridine; Vinblastine

1969
Potentiation of the teratogenic effects of 5-fluorouracil by natural pyrimidines. I. Biological aspects.
    Teratology, 1969, Volume: 2, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Carbon Isotopes; Carbon Tetrachloride Poisoning; Drug Synergism; Embryo, Mammalian; Female; Fluorouracil; Injections, Intraperitoneal; Kidney; Liver; Male; Maternal-Fetal Exchange; Pregnancy; Pyrimidines; Rats; Thymidine; Thymine; Uracil; Uridine

1969
Potentiation of the teratogenic effects of 5-fluorouracil by natural pyrimidines. II. Biochemical aspects.
    Teratology, 1969, Volume: 2, Issue:2

    Topics: Animals; Carbon Isotopes; Depression, Chemical; DNA; Drug Synergism; Embryo, Mammalian; Extraembryonic Membranes; Female; Fluorouracil; Formates; Injections, Intraperitoneal; Ligases; Liver; Male; Phosphorus; Phosphorus Isotopes; Pregnancy; Rats; Thymidine; Thymidine Kinase; Thymine; Uracil

1969
Mechanism of growth inhibition by 5-fluorouracil. Reversal studies with pyrimidine metabolites in vitro.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 131, Issue:3

    Topics: Animals; Carcinoma, Ehrlich Tumor; Culture Techniques; Depression, Chemical; DNA, Neoplasm; Fluorouracil; Mice; Nucleotides; Orotic Acid; RNA, Neoplasm; Thymidine; Uridine

1969
Control of certain aspects of the infective process by progeny viral DNA.
    Virology, 1965, Volume: 26, Issue:4

    Topics: Animals; Bromodeoxyuridine; DNA; DNA, Viral; Enzymes; Fluorouracil; Herpesviridae; In Vitro Techniques; Kidney; Protein Biosynthesis; Puromycin; Rabbits; Thymidine; Virus Cultivation

1965
The synergistic anti-neoplastic activity of combinations of mitomycins with either 6-thioguanine or 5-fluorouracil.
    Cancer research, 1965, Volume: 25, Issue:9

    Topics: Animals; Antineoplastic Agents; DNA, Neoplasm; Drug Synergism; Female; Fluorouracil; In Vitro Techniques; Leukemia L1210; Lysine; Male; Mice; Mitomycins; Mortality; Neoplasm Proteins; Neoplasm Transplantation; Orotic Acid; RNA, Neoplasm; Sarcoma 180; Thioguanine; Thymidine; Thymidine Kinase

1965
Kinetics of proliferation of cancer cells in neoplastic effusions in man.
    Cancer, 1965, Volume: 18, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Agents; Autoradiography; Cell Division; DNA, Neoplasm; Exudates and Transudates; Female; Fluorouracil; Humans; Lymphoma; Middle Aged; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Stomach Neoplasms; Thymidine; Tritium; Uterine Neoplasms

1965
Morphogenesis in Trichoderma: suppression of photoinduction by 5-fluorouracil.
    Science (New York, N.Y.), 1966, Feb-11, Volume: 151, Issue:3711

    Topics: Carbon Isotopes; Cytosine Nucleotides; DNA; Fluorouracil; In Vitro Techniques; Mitosporic Fungi; Radiometry; RNA; Spores; Thymidine; Uracil; Uracil Nucleotides

1966
Effects of ultraviolet radiation on RNA C-C glycosyls and other derivatives of uracil.
    Radiation research, 1966, Volume: 29, Issue:4

    Topics: Chemical Phenomena; Chemistry, Physical; Fluorouracil; Nucleosides; Radiation Effects; RNA, Transfer; Spectrophotometry; Thymidine; Thymine; Ultraviolet Rays; Uracil; Uridine

1966
A model system for examining the action of anti-cancer agents at the cellular level in vivo.
    National Cancer Institute monograph, 1967, Volume: 24

    Topics: Animals; Antineoplastic Agents; Azaserine; Cyclophosphamide; Dactinomycin; Fluorouracil; Hematopoiesis; Lymphoma; Mechlorethamine; Methotrexate; Mice; Models, Theoretical; Neoplasm Transplantation; Neoplasms, Experimental; Spleen; Thymidine; Tritium; Vinblastine

1967
Dual function of the lambda prophage repressor.
    Journal of molecular biology, 1967, May-14, Volume: 25, Issue:3

    Topics: Adenine; Coliphages; DNA, Viral; Fluorouracil; Hot Temperature; Leucine; Molecular Biology; Mutation; Thymidine; Viral Proteins

1967
Enhancement of 5 fluorouracil cytotoxicity in synchronized human malignant cells in culture.
    Texas reports on biology and medicine, 1967,Fall, Volume: 25, Issue:3

    Topics: Culture Techniques; DNA, Neoplasm; Fluorouracil; HeLa Cells; Humans; Mitosis; Thymidine; Tritium

1967
Uridine rescue from the lethal toxicity of 5-fluorouracil in mice.
    Cancer chemotherapy and pharmacology, 1982, Volume: 8, Issue:1

    Topics: Animals; Deoxyuridine; Fluorouracil; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; RNA; Thymidine; Uridine

1982
[Autoradiography studies of cell proliferation and the effect of cytostatic agents on the proliferation of normal and tumor cells].
    Acta histochemica. Supplementband, 1983, Volume: 27

    Topics: Animals; Antineoplastic Agents; Autoradiography; Bleomycin; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Division; Fluorouracil; Jejunum; Mice; Rats; Tegafur; Thymidine; Vincristine

1983
5-fluorouracil modulation of dihydrofolate reductase RNA levels in methotrexate-resistant KB cells.
    The Journal of biological chemistry, 1983, Nov-10, Volume: 258, Issue:21

    Topics: Carcinoma; Cell Division; Cell Line; Clone Cells; Fluorouracil; Gene Amplification; Humans; Kinetics; Mouth Neoplasms; Poly A; RNA; RNA, Messenger; RNA, Neoplasm; Tetrahydrofolate Dehydrogenase; Thymidine; Transcription, Genetic

1983
Thymidine enhancement of methotrexate and 5-fluorouracil toxicity in cultured human colon carcinoma.
    Cancer chemotherapy and pharmacology, 1984, Volume: 12, Issue:2

    Topics: Cells, Cultured; Colonic Neoplasms; Drug Interactions; Flow Cytometry; Fluorouracil; Humans; Kinetics; Methotrexate; RNA; Thymidine

1984
Modulation of 5-fluorouracil metabolism by thymidine. In vivo and in vitro studies on RNA-directed effects in rat liver and hepatoma.
    Biochemical pharmacology, 1984, Mar-01, Volume: 33, Issue:5

    Topics: Animals; Body Weight; Bone Marrow; Cell Survival; Fluorouracil; Intestinal Mucosa; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred Strains; RNA; Thymidine

1984
Clinical pharmacological studies of concurrent infusion of 5-fluorouracil and thymidine in treatment of colorectal carcinomas.
    Cancer research, 1982, Volume: 42, Issue:7

    Topics: Colonic Neoplasms; Drug Therapy, Combination; Floxuridine; Fluorouracil; Humans; Infusions, Parenteral; Rectal Neoplasms; Thymidine; Thymine

1982
5-Fluorouracil incorporation in DNA of human breast carcinoma cells.
    Cancer research, 1982, Volume: 42, Issue:8

    Topics: Breast Neoplasms; Cell Line; DNA Replication; DNA, Neoplasm; Female; Floxuridine; Fluorouracil; Humans; Kinetics; Phosphorus Radioisotopes; Thymidine; Tritium

1982
Enhancement of the incorporation of 5-fluorodeoxyuridylate into DNA of HL-60 cells by metabolic modulations.
    Cancer research, 1983, Volume: 43, Issue:11

    Topics: Cell Line; Deoxyuracil Nucleotides; DNA Replication; DNA, Neoplasm; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Kinetics; Leukemia, Myeloid, Acute; Methotrexate; Thymidine; Tritium

1983
Prognostic factors and in vitro cytotoxic sensitivity in colorectal cancer.
    The British journal of surgery, 1984, Volume: 71, Issue:12

    Topics: Antineoplastic Agents; Cell Division; Cell Survival; Cells, Cultured; Colonic Neoplasms; Floxuridine; Fluorouracil; Humans; Neoplasm Staging; Prognosis; Rectal Neoplasms; Thymidine; Tumor Stem Cell Assay

1984
[Experiences with Volm's short-term tumor test in the primary treatment of ovarian carcinoma].
    Onkologie, 1984, Volume: 7 Suppl 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cell Division; Cells, Cultured; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Resistance; Female; Fluorouracil; Humans; Ovarian Neoplasms; Prognosis; Thymidine; Uridine

1984
[Regulation of enzyme activities involved in pyrimidine synthesis and its application to cancer chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:3 Pt 2

    Topics: Administration, Oral; Animals; Deoxyuridine; Dihydrouracil Dehydrogenase (NAD+); DNA, Neoplasm; Drug Synergism; Fluorouracil; Neoplasms, Experimental; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Pentosyltransferases; Phosphorylation; Pyrimidines; Sarcoma, Yoshida; Tegafur; Thymidine; Thymine; Uracil; Uridine

1984
Effects of thymidine and thymidine plus 5-fluorouracil on the growth kinetics of a human lymphoid cell line.
    Cancer research, 1980, Volume: 40, Issue:5

    Topics: Cell Cycle; Cell Division; Cell Line; Cell Survival; DNA Replication; Floxuridine; Fluorouracil; Humans; Thymidine; Thymine

1980
Role of uridine phosphorylase for antitumor activity of 5'-deoxy-5-fluorouridine.
    Gan, 1980, Volume: 71, Issue:1

    Topics: Animals; Biotransformation; Floxuridine; Fluorouracil; Leukemia L1210; Male; Mice; Pentosyltransferases; Sarcoma 180; Tegafur; Thymidine; Uridine; Uridine Phosphorylase

1980
Regulation of RNA- and DNA-directed actions of 5-fluoropyrimidines in mouse T-lymphoma (S-49) cells.
    Cancer research, 1980, Volume: 40, Issue:11

    Topics: Animals; Cell Cycle; DNA, Neoplasm; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Leukemia, Experimental; Lymphoma; Mice; Pyrimidine Nucleotides; Pyrimidines; RNA, Neoplasm; Thymidine

1980
A combination of 5-fluorouracil and thymidine in advanced colorectal carcinoma.
    Cancer chemotherapy and pharmacology, 1984, Volume: 13, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Colonic Neoplasms; Drug Synergism; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms; Thymidine

1984
Clinical trial of sequential N-phosphonacetyl-L-aspartate, thymidine, and 5-fluorouracil in advanced colorectal carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Ataxia; Colonic Neoplasms; Confusion; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Infusions, Parenteral; Male; Middle Aged; Phosphonoacetic Acid; Rectal Neoplasms; Thymidine

1984
Chemotherapeutic efficacy of 5-fluorouracil with concurrent thymidine infusion against transplantable colon tumors in rodents.
    Cancer drug delivery, 1984,Fall, Volume: 1, Issue:4

    Topics: Animals; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Thymidine

1984
Critical modulation by thymidine and hypoxanthine of sequential methotrexate-5-fluorouracil synergism in murine L1210 cells.
    Cancer research, 1983, Volume: 43, Issue:11

    Topics: Animals; Cell Survival; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Hypoxanthine; Hypoxanthines; Kinetics; Leukemia L1210; Methotrexate; Mice; Thymidine

1983
Combined cytotoxic effect of low-dose 5-fluorouracil and hydroxyurea on 9L cells in vitro.
    Cancer research, 1983, Volume: 43, Issue:11

    Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Hydroxyurea; Kinetics; Rats; Thymidine

1983
Factors modifying the synergistic toxicity of deoxycytidine in combination with thymidine plus 5-fluorouracil in HeLa cells.
    Cell and tissue kinetics, 1983, Volume: 16, Issue:6

    Topics: Cell Survival; Culture Media; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Fluorouracil; HeLa Cells; Humans; Hypoxanthine; Hypoxanthines; Interphase; Kinetics; Mitosis; Thymidine

1983
Phase I evaluation of a biochemically designed combination: PALA, thymidine, and 5-FU.
    Cancer treatment reports, 1984, Volume: 68, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Drug Evaluation; Fluorouracil; Humans; Neoplasms; Nervous System; Phosphonoacetic Acid; Thymidine

1984
Human tissues degrade uridine much less than thymidine. Possible consequence for 5-fluorouracil therapy.
    Biochemical pharmacology, 1984, Mar-01, Volume: 33, Issue:5

    Topics: Animals; Deoxyuridine; Fluorouracil; Humans; In Vitro Techniques; Liver; Mice; Models, Biological; Pentosyltransferases; Pyrimidine Phosphorylases; Rats; Spleen; Thymidine; Tissue Distribution; Uridine

1984
Purine and pyrimidine analogues irreversibly prevent passage of lymphocytes from the G1 to the S phase of the cell cycle.
    Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire, 1984, Volume: 62, Issue:5

    Topics: Animals; Azaguanine; DNA Replication; Fluorouracil; Humans; Interphase; Lymphocyte Activation; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Potassium; Protein Biosynthesis; Thymidine; Thymidylate Synthase

1984
Effect of coadministration of thymine or thymidine on the antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil and 5-fluorouracil.
    Gan, 1980, Volume: 71, Issue:1

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Biodegradation, Environmental; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Liver; Male; Mice; Phosphorylation; Rats; Sarcoma 180; Sarcoma, Yoshida; Tegafur; Thymidine; Thymidine Phosphorylase; Thymine; Uracil; Uridine; Uridine Phosphorylase

1980
Effect of DNA inhibitors upon DNA synthesis and development of Drosophila embryos.
    The Journal of experimental zoology, 1980, Volume: 212, Issue:2

    Topics: Age Factors; Animals; Arabinonucleotides; Cytidine Monophosphate; DNA; Drosophila melanogaster; Fluorouracil; Mitomycins; Nalidixic Acid; Thymidine; Time Factors

1980
Comparing cell kinetic studies of the effect of ftorafur and 5-fluorouracil on the L 1210 ascites tumor.
    Journal of cancer research and clinical oncology, 1981, Volume: 100, Issue:1

    Topics: Animals; Cell Division; Female; Fluorouracil; Kinetics; Leukemia L1210; Mice; Mitosis; Neoplasm Transplantation; Tegafur; Thymidine; Transplantation, Homologous; Uridine

1981
Nonlinear pharmacokinetics of thymidine, thymine, and fluorouracil and their kinetic interactions in normal dogs.
    Cancer research, 1983, Volume: 43, Issue:10

    Topics: Animals; Dogs; Drug Interactions; Fluorouracil; Kinetics; Metabolic Clearance Rate; Thymidine; Thymine

1983
Improving the anti-tumor activity of 5-fluorouracil by increasing its incorporation into RNA via metabolic modulation.
    Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:8

    Topics: Animals; DNA, Neoplasm; Drug Synergism; Female; Fluorouracil; Glycoproteins; Mammary Neoplasms, Experimental; Mice; Neoplasm Proteins; RNA, Neoplasm; Thymidine

1980
Effect of excess folates and deoxyinosine on the activity and site of action of 5-fluorouracil.
    Cancer research, 1981, Volume: 41, Issue:9 Pt 1

    Topics: Animals; Carcinoma; Cell Line; Deoxyribonucleosides; Deoxyribose; Deoxyuridine; Drug Synergism; Fluorouracil; Humans; Inosine; Leucovorin; Mice; Sarcoma, Experimental; Thymidine; Thymidylate Synthase

1981
Partial protection of the gastric toxicity of regional 5-fluorouracil infusion by thymidine and cimetidine.
    Journal of surgical oncology, 1982, Volume: 20, Issue:3

    Topics: Animals; Cimetidine; Dogs; Fluorouracil; Gastric Acid; Gastric Mucosa; Guanidines; Infusions, Intra-Arterial; Stomach; Stomach Ulcer; Thymidine

1982
A selection system specific for the Thy mutator phenotype.
    Somatic cell genetics, 1982, Volume: 8, Issue:4

    Topics: Animals; Cell Line; Cell Separation; Cricetinae; Cricetulus; Cytarabine; Deoxyribonucleotides; Drug Resistance; Female; Fluorouracil; Mutation; Ovary; Thymidine

1982
Comparative investigations on the effect of 5-fluorouracil on the epidermis and the skin appendages.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:8

    Topics: Animals; Cell Division; Cricetinae; Fluorouracil; Guinea Pigs; Hair; Male; Mesocricetus; Sebaceous Glands; Skin; Thymidine; Time Factors

1981
Failure of 5-fluorouracil and methotrexate to destroy the reproductive integrity of a human breast cancer cell line (MCF-7) growing in vitro.
    European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:12

    Topics: Breast Neoplasms; Cell Division; Cell Line; Cell Survival; Clone Cells; Deoxyuridine; DNA, Neoplasm; Dose-Response Relationship, Drug; Fluorouracil; Humans; Male; Methotrexate; Thymidine

1981
Penetration of substances into tumor tissue--a methodological study on cellular spheroids.
    In vitro, 1981, Volume: 17, Issue:4

    Topics: Albumins; Biological Transport; Cell Line; Clone Cells; Fluorouracil; Glioma; Humans; Leucine; Models, Biological; Neoplasms; Thymidine; Vinblastine

1981
Cytotoxic and cytokinetic effects of thymidine, 5-fluorouracil, and deoxycytidine on HeLa cells in culture.
    Cancer research, 1981, Volume: 41, Issue:7

    Topics: Cell Division; Cell Survival; Colony-Forming Units Assay; Deoxycytidine; DNA; Dose-Response Relationship, Drug; Fluorouracil; HeLa Cells; Humans; Thymidine; Time Factors

1981
Influence of pH and serum on the effectivity of antineoplastic agents in vitro.
    Archiv fur Geschwulstforschung, 1981, Volume: 51, Issue:1

    Topics: Antineoplastic Agents; Cells, Cultured; Culture Media; Fluorouracil; Humans; Hydrogen-Ion Concentration; Mesothelioma; Thymidine; Uridine; Vinblastine

1981
Carbocyclic analogues of 5-fluorouracil nucleosides.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:9

    Topics: Animals; Antineoplastic Agents; Fluorouracil; Leukemia L1210; Leukemia P388; Mice; Nucleosides; Thymidine

1981
Modulation of 5-FU action by thymidine in murine and human tumors.
    Cancer treatment reports, 1981, Volume: 65 Suppl 3

    Topics: Animals; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Fluorouracil; Humans; Kinetics; Mice; Neoplasms; Neoplasms, Experimental; Species Specificity; Thymidine

1981
Comparison of pharmacokinetics of 5-fluorouracil and 5-fluorouracil with concurrent thymidine infusions in a Phase I trial.
    Cancer research, 1980, Volume: 40, Issue:1

    Topics: Adult; Bone Marrow; Drug Evaluation; Female; Fluorouracil; Half-Life; Humans; Infusions, Parenteral; Male; Middle Aged; Neoplasms; Thymidine

1980
Potentiation of the anti-tumor activity of 5FU by thymidine and its correlation with the formation of (5FU)RNA.
    Cancer, 1980, Mar-15, Volume: 45, Issue:5 Suppl

    Topics: Animals; Colonic Neoplasms; DNA, Neoplasm; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; RNA, Neoplasm; Thymidine; Thymidine Kinase

1980
Combination clinical trials with thymidine and fluorouracil: a phase I and clinical pharmacologic evaluation.
    Cancer, 1980, Mar-15, Volume: 45, Issue:5 Suppl

    Topics: Adult; Aged; Bone Marrow; Colonic Neoplasms; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphoma; Middle Aged; Neoplasms; Ovarian Neoplasms; Thymidine

1980
Dynamic histology of a rat hepatoma and the response to 5-fluorouracil.
    Cell and tissue kinetics, 1980, Volume: 13, Issue:1

    Topics: Animals; DNA, Neoplasm; Female; Fluorouracil; Kinetics; Liver Neoplasms, Experimental; Mitotic Index; Rats; Rats, Inbred ACI; Thymidine; Uridine

1980
Protection by testosterone from fluorouracil-induced toxicity without loss of anticancer acitvity against autochthonous murine breast tumors.
    Cancer research, 1980, Volume: 40, Issue:8 Pt 1

    Topics: Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Leukocyte Count; Male; Mammary Neoplasms, Experimental; Mice; Testosterone; Thymidine

1980
The in vivo incorporation of triated thymidine into liver cell nuclear DNA in mice treated chronically with carbon tetrachloride or with diethylnitrosamine.
    Experimental and molecular pathology, 1980, Volume: 33, Issue:1

    Topics: Animals; Bromodeoxyuridine; Carbon Tetrachloride Poisoning; Cell Nucleus; Diethylnitrosamine; DNA; DNA Repair; Fluorouracil; Hydroxyurea; Liver; Mice; Nitrosamines; Thymidine

1980
[Experimental study of the combined effect of 5-fluorouracil and cyclophosphane on growth of Zajdela hepatoma and nucleic acid metabolism].
    Biulleten' eksperimental'noi biologii i meditsiny, 1980, Volume: 90, Issue:10

    Topics: Animals; Cyclophosphamide; DNA, Neoplasm; Drug Therapy, Combination; Fluorouracil; Liver Neoplasms, Experimental; Male; Neoplasm Transplantation; Rats; RNA, Neoplasm; Thymidine; Uridine

1980
Clinical pharmacologic effects of thymidine plus 5-FU.
    Cancer treatment reports, 1980, Volume: 64, Issue:12

    Topics: Adult; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukocyte Count; Male; Middle Aged; Neoplasms; Platelet Count; Thymidine; Thymine; Time Factors

1980
Characterization of trimethoprim- and sulphisoxazole-resistant Chlamydia trachomatis.
    Molecular microbiology, 1994, Volume: 14, Issue:2

    Topics: Adenosine Triphosphate; Animals; Chlamydia trachomatis; DNA, Bacterial; Drug Resistance, Microbial; Fluorouracil; Guanosine Triphosphate; L Cells; Methotrexate; Mice; Microbial Sensitivity Tests; Mutation; Phenotype; RNA, Bacterial; Sulfisoxazole; Thymidine; Trimethoprim; Uracil; Zidovudine

1994
Fas receptor (CD95)-mediated apoptosis is induced in leukemic cells entering G1B compartment of the cell cycle.
    Blood, 1995, Nov-15, Volume: 86, Issue:10

    Topics: Acute Disease; Antibodies, Monoclonal; Apoptosis; Cell Division; Child; Child, Preschool; DNA Damage; DNA, Neoplasm; fas Receptor; Fluorouracil; G1 Phase; Humans; Leukemia, Myeloid; Neoplastic Stem Cells; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured

1995
Increased sensitivity to the prodrug 5'-deoxy-5-fluorouridine and modulation of 5-fluoro-2'-deoxyuridine sensitivity in MCF-7 cells transfected with thymidine phosphorylase.
    British journal of cancer, 1995, Volume: 72, Issue:3

    Topics: Antineoplastic Agents; Biological Availability; Breast; Breast Neoplasms; Cell Communication; Cell Division; Drug Screening Assays, Antitumor; Floxuridine; Fluorouracil; Humans; Prodrugs; Thymidine; Thymidine Phosphorylase; Transfection; Tumor Cells, Cultured

1995
Thymidylate synthase gene amplification in human colon cancer cell lines resistant to 5-fluorouracil.
    Biochemical pharmacology, 1995, May-17, Volume: 49, Issue:10

    Topics: Cell Division; Cell Line; Colonic Neoplasms; DNA, Neoplasm; Drug Resistance; Fluorouracil; Gene Amplification; Humans; RNA, Messenger; Thymidine; Thymidylate Synthase; Up-Regulation

1995
Antibiotic C3368-A, a fungus-derived nucleoside transport inhibitor, potentiates the activity of antitumor drugs.
    Cancer chemotherapy and pharmacology, 1995, Volume: 36, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzofurans; Biological Transport; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Division; Colonic Neoplasms; Doxorubicin; Drug Synergism; Female; Fluorouracil; Humans; KB Cells; Liver Neoplasms; Methotrexate; Mice; Mice, Inbred BALB C; Mitomycin; Spiro Compounds; Thymidine; Tumor Cells, Cultured; Tumor Stem Cell Assay; Uridine

1995
Enhanced cytotoxicity with interleukin-1 alpha and 5-fluorouracil in HCT116 colon cancer cells.
    Oncology research, 1994, Volume: 6, Issue:12

    Topics: Biotransformation; Cell Division; Colonic Neoplasms; DNA, Neoplasm; Drug Synergism; Fluorouracil; Humans; Interleukin-1; Prodrugs; Receptors, Interleukin-1; Recombinant Proteins; RNA, Neoplasm; Thymidine; Thymine Nucleotides; Tumor Cells, Cultured; Tumor Stem Cell Assay; Uridine; Uridine Triphosphate

1994
SMS 201.995 (Sandostatin) enhances in-vitro effects of 5-fluorouracil in colorectal cancer.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1995, Volume: 21, Issue:1

    Topics: Adenocarcinoma; Carcinoma; Colonic Neoplasms; Colorimetry; Drug Synergism; Fluorouracil; Humans; Octreotide; Thymidine; Tumor Cells, Cultured

1995
Relationship of variations in tumor cell kinetics induced by primary chemotherapy to tumor regression and prognosis in locally advanced breast cancer.
    Breast cancer research and treatment, 1994, Volume: 32, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Thymidine

1994
Aberrant cell cycle inhibition pattern in human colon carcinoma cell lines after exposure to 5-fluorouracil.
    Biochemical pharmacology, 1995, Feb-14, Volume: 49, Issue:4

    Topics: Cell Cycle; Colonic Neoplasms; DNA; Drug Interactions; Fluorouracil; Humans; Leucovorin; S Phase; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured

1995
Dependence of 5-fluorouracil-mediated radiosensitization on DNA-directed effects.
    International journal of radiation oncology, biology, physics, 1994, Jun-15, Volume: 29, Issue:3

    Topics: Cell Cycle; Colonic Neoplasms; DNA; Fluorouracil; Humans; Radiation-Sensitizing Agents; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured

1994
BIBW 22, a dipyridamole analogue, acts as a bifunctional modulator on tumor cells by influencing both P-glycoprotein and nucleoside transport.
    Cancer research, 1993, May-01, Volume: 53, Issue:9

    Topics: Affinity Labels; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Membrane Permeability; Dipyridamole; Drug Synergism; Fluorouracil; Humans; Membrane Glycoproteins; Morpholines; Nucleosides; Photochemistry; Thymidine; Triamterene; Tumor Cells, Cultured; Vincristine

1993
DNA synthesis after combined treatment with cisplatin and 5-fluorouracil of a mouse ascites tumor growing in vivo.
    Anti-cancer drugs, 1994, Volume: 5, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Chromatography, High Pressure Liquid; Cisplatin; Cross-Linking Reagents; DNA, Neoplasm; Fluorouracil; Male; Mice; Neoplasms, Experimental; Thymidine; Thymidylate Synthase; Thymine Nucleotides; Tumor Cells, Cultured

1994
Semiautomated 14C-thymidine incorporation assay for in vitro screening of anticancer drug.
    Human cell, 1993, Volume: 6, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Carbon Radioisotopes; Carcinoma, Signet Ring Cell; Cell Division; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Mitomycin; Stomach Neoplasms; Tamoxifen; Thymidine; Tumor Cells, Cultured

1993
Characterization of a 5-fluorouracil-enriched osteoprogenitor population of the murine bone marrow.
    Blood, 1993, Dec-15, Volume: 82, Issue:12

    Topics: Alkaline Phosphatase; Animals; Bone Marrow; Bone Marrow Cells; Calcium; Cell Adhesion; Cells, Cultured; Collagen; Colony-Forming Units Assay; DNA; Durapatite; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fluorouracil; Hematopoietic Stem Cells; In Situ Hybridization; Kinetics; Mice; Mice, Inbred BALB C; Microscopy, Electron; Microscopy, Electron, Scanning; Minerals; Nylons; Osteoblasts; Osteocalcin; Plastics; Stem Cells; Thymidine; X-Ray Diffraction

1993
Effects of 5-fluorouracil on embryonic rat palate in vitro: fusion in the absence of proliferation.
    Teratology, 1993, Volume: 47, Issue:6

    Topics: Animals; Cell Cycle; Cell Division; Cleft Palate; DNA; Embryo, Mammalian; Fluorouracil; Gestational Age; Organ Culture Techniques; Palate; Rats; Rats, Sprague-Dawley; Thymidine

1993
5-Fluorouracil metabolism and cytotoxicity after pre-treatment with methotrexate or thymidine in human hypopharynx and colon carcinoma xenografts: a 19F-nuclear magnetic resonance spectroscopy study in vivo.
    Cancer chemotherapy and pharmacology, 1996, Volume: 37, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma; Colonic Neoplasms; Fluorine Radioisotopes; Fluorouracil; Humans; Magnetic Resonance Spectroscopy; Methotrexate; Mice; Mice, Nude; Pharyngeal Neoplasms; Thymidine; Transplantation, Heterologous

1996
Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: evidence for the involvement of RNA perturbation.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Mar-04, Volume: 94, Issue:5

    Topics: Animals; Apoptosis; Colon; Enzyme Inhibitors; Fluorouracil; Folic Acid Antagonists; Gene Expression Regulation; Histocytochemistry; Immunohistochemistry; Intestinal Mucosa; Intestine, Small; Male; Mice; Mice, Inbred Strains; Quinazolines; RNA; Thiophenes; Thymidine; Thymidylate Synthase; Tumor Suppressor Protein p53; Uridine

1997
Cell proliferation as a predictor of response to chemotherapy in metastatic breast cancer: a prospective study.
    Breast cancer research and treatment, 1997, Volume: 43, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Prospective Studies; Thymidine; Tumor Cells, Cultured

1997
Irreversible cytotoxic effect of a novel lowly immunosuppressive antitumor fluorouridine derivative, UK-21.
    Anti-cancer drugs, 1997, Volume: 8, Issue:5

    Topics: Antimetabolites, Antineoplastic; Cell Cycle; Cell Survival; Flow Cytometry; Floxuridine; Fluorouracil; Glycine; Humans; Immunosuppressive Agents; KB Cells; Neoplastic Stem Cells; Thymidine; Uridine

1997
Inhibition by 5-fluorouracil of ERCC1 and gamma-glutamylcysteine synthetase messenger RNA expression in a cisplatin-resistant HST-1 human squamous carcinoma cell line.
    Oncology research, 1997, Volume: 9, Issue:4

    Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cisplatin; DNA Repair; DNA Topoisomerases, Type I; DNA-Binding Proteins; Drug Resistance, Neoplasm; Endonucleases; Fluorouracil; Gene Expression Regulation, Neoplastic; Glutamate-Cysteine Ligase; Humans; Proteins; RNA, Messenger; RNA, Neoplasm; Thymidine

1997
Nucleoside-mediated mitigation of 5-fluorouracil-induced toxicity in synchronized murine erythroleukemic cells.
    Toxicology and applied pharmacology, 1997, Volume: 146, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Cycle; Deoxycytidine; Deoxyguanine Nucleotides; Embryo, Mammalian; Female; Flow Cytometry; Fluorouracil; Leukemia, Erythroblastic, Acute; Mice; Pregnancy; Rats; Rats, Sprague-Dawley; Thymidine; Thymine Nucleotides

1997
5-Fluorouracil-resistant colonic tumors are highly responsive to sodium butyrate/interleukin-2 bitherapy in rats.
    International journal of cancer, 1997, Dec-10, Volume: 73, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Butyrates; Butyric Acid; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Fluorouracil; Interleukin-2; Mice; Mice, Nude; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Recombinant Proteins; Survival Rate; Thymidine; Tumor Cells, Cultured

1997
Dihydropyrimidine dehydrogenase in livers from mouse and rat, and in human liver, colon tumors, and mucosa in relation to anabolism of 5-fluorouracil.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Animals; Biological Availability; Biotransformation; Colonic Neoplasms; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Humans; Intestinal Mucosa; Kinetics; Liver; Mice; Oxidoreductases; Rats; Species Specificity; Thymidine; Thymine; Uracil

1998
A pharmacokinetic and pharmacodynamic study in vivo of human HT29 tumours using 19F and 31P magnetic resonance spectroscopy.
    European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:14

    Topics: Animals; Antineoplastic Agents; Fluorouracil; HT29 Cells; Humans; Interferon-alpha; Liver Neoplasms, Experimental; Magnetic Resonance Spectroscopy; Mice; Mice, Nude; Neoplasm Transplantation; Thymidine

1997
Antitumor activity of ZD1694 (tomudex) against human head and neck cancer in nude mouse models: role of dosing schedule and plasma thymidine.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:7

    Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Quinazolines; Thiophenes; Thymidine; Transplantation, Heterologous; Tumor Cells, Cultured

1999
An update on thymidylate synthase inhibitors.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1999, Volume: 10, Issue:10

    Topics: Antimetabolites, Antineoplastic; Fluorouracil; Humans; Neoplasms; Thymidine; Thymidylate Synthase

1999
Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Division; Cell Line; Databases, Factual; Dihydrouracil Dehydrogenase (NADP); DNA; Drug Screening Assays, Antitumor; Floxuridine; Fluorouracil; Humans; Mutation; National Institutes of Health (U.S.); Oxidoreductases; RNA, Messenger; Thymidine; Thymidine Kinase; Thymidylate Synthase; Tumor Cells, Cultured; Tumor Suppressor Protein p53; United States

2001
Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors.
    Cancer research, 2001, May-01, Volume: 61, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Division; Colonic Neoplasms; Diet; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Female; Fluorouracil; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Leucovorin; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Pemetrexed; Quinazolines; Thiophenes; Thymidine; Thymidine Kinase; Thymidylate Synthase

2001
Serum factors attenuating the anti-tumor activity of 5-fluorouracil.
    Cancer biotherapy & radiopharmaceuticals, 2001, Volume: 16, Issue:4

    Topics: Antimetabolites, Antineoplastic; Colonic Neoplasms; Cytokines; DNA, Neoplasm; Drug Interactions; Drug Resistance; Fluorouracil; Humans; Immunoblotting; Interferon-gamma; Interleukin-1; Interleukin-6; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2001
Lymphoblasts already in the DNA synthesis phase of the cell cycle can be reversibly arrested at the R/G transition.
    Chromosoma, 2001, Volume: 110, Issue:7

    Topics: Bromodeoxyuridine; Cell Cycle; Cell Line, Transformed; Chromosome Banding; Chromosomes, Human; DNA; DNA Replication; Flow Cytometry; Fluorouracil; Humans; Karyotyping; Kinetics; Lymphocyte Activation; Lymphocytes; Methotrexate; Mimosine; S Phase; Thymidine

2001
Turnover of thymidine in the DNA of marrow and intestinal mucosa in mice, and its response to administration of 5-fluorouracil.
    Cancer research, 1961, Volume: 21

    Topics: Animals; Antineoplastic Agents; Bone Marrow; DNA; Fluorouracil; Intestinal Mucosa; Mice; Nucleosides; Nucleotides; Thymidine; Uracil

1961
[Studies on the mechanism of induction. I. The effect of some base analogs on lysogenic bacteria].
    Acta biologica et medica Germanica, 1963, Volume: 10

    Topics: Bacteria; Culture Media; Escherichia coli; Floxuridine; Fluorouracil; Lysogeny; Thymidine

1963
The coupled formation of deoxyribonucleic acid, nuclear ribonucleic acid and protein in animal-cell cultures.
    Biochimica et biophysica acta, 1962, Sep-17, Volume: 61

    Topics: Cell Culture Techniques; DNA; Floxuridine; Fluorouracil; Nucleosides; Proteins; RNA; Thymidine; Tissue Culture Techniques

1962
Effects of uracil and thymidine on the development of resistance to 5-fluorouracil in Pediococcus cerevisiae.
    Journal of bacteriology, 1963, Volume: 85

    Topics: Deoxyuridine; Fluorouracil; Pediococcus; Thymidine; Uracil

1963
KINETIC STUDY OF THE INHIBITION OF GROWTH OF ROUS SARCOMA VIRUS AND CELLS BY 5-FLUOROURACIL IN VITRO.
    Virology, 1963, Volume: 20

    Topics: Animals; Avian Sarcoma Viruses; Chick Embryo; Culture Media; Fluorouracil; In Vitro Techniques; Research; Rous sarcoma virus; Thymidine; Virus Cultivation

1963
NUCLEIC ACID METABOLISM AND BACTERIOPHAGE MULTIPLICATION: EFFECTS OF 5-FLUOROURACIL ON COLIPHAGE SYNTHESIS.
    Virology, 1963, Volume: 21

    Topics: Bacteriophages; Coliphages; DNA; DNA, Viral; Fluorouracil; RNA; RNA, Viral; Thymidine; Uracil

1963
EFFECT OF 5-FLUOROURACIL ON REGENERATION IN TADPOLES.
    Nature, 1963, Aug-10, Volume: 199

    Topics: Animals; Anura; DNA; Fluorouracil; Larva; Metabolism; Pharmacology; Regeneration; Research; Thymidine; Tritium

1963
INDUCTION BY 5-FLUOROURACIL OF BACTERIOPHAGE DEVELOPMENT IN LYSOGENIC E. COLI K12 (LAMBDA).
    Nature, 1963, Nov-02, Volume: 200

    Topics: Bacteriophages; Coliphages; Escherichia coli; Fluorouracil; Lysogeny; Research; Thymidine; Uracil

1963
EFFECTS OF 5-FLUOROURACIL, ACTINOMYCIN D AND MITOMYCIN C ON THE INDUCTION OF THYMIDINE KINASE BY VACCINIA-INFECTED L-CELLS.
    Journal of molecular biology, 1963, Volume: 7

    Topics: Dactinomycin; DNA; DNA, Viral; Enzyme Inhibitors; Floxuridine; Fluorouracil; Metabolism; Mice; Mitomycin; Mitomycins; Pharmacology; Phosphotransferases; Research; RNA; RNA, Viral; Thymidine; Thymidine Kinase; Tissue Culture Techniques; Tritium; Vaccinia; Vaccinia virus; Virus Cultivation

1963
EFFECT OF HALOGENATED PYRIMIDINES AND THYMIDINE ON GROWTH OF L-CELLS AND A SUBLINE LACKING THYMIDINE KINASE.
    Experimental cell research, 1964, Volume: 33

    Topics: Animals; Connective Tissue; Fluorouracil; L Cells; Metabolism; Mice; Pharmacology; Phosphotransferases; Pyrimidines; Research; Thymidine; Thymidine Kinase; Tissue Culture Techniques; Tritium

1964
UTILIZATION OF DNA AND RNA PRECURSORS AS INDICATORS OF DRUG EFFECT ON CANCER CELLS. ANL-6723.
    ANL, 1963

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Dactinomycin; DNA; DNA, Neoplasm; Fluorouracil; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mechlorethamine; Mice; Neoplasms; Nucleosides; Pharmacology; Research; RNA Precursors; Thymidine; Tritium

1963
THE CLINICAL EFFECTS OF THE CONTINUOUS INTRAVENOUS INFUSION OF CANCER CHEMOTHERAPEUTIC COMPOUNDS.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antineoplastic Agents; Floxuridine; Fluorouracil; Infusions, Intravenous; Infusions, Parenteral; Methotrexate; Mitomycin; Mitomycins; Neoplasms; Thymidine

1964
THE EFFECT OF NATURAL AND UNNNATURAL PYRIMIDINES AND PYRIMIDINE NUCLEOSIDES ON THE PHOSPHOROLYSIS OF 5-IODODEOXYURIDINE BY MOUSE LIVER EXTRACT.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Animals; Chromatography; Deoxyuridine; Floxuridine; Fluorouracil; Idoxuridine; Iodine Isotopes; Liver; Liver Extracts; Metabolism; Mice; Nucleosides; Pharmacology; Phosphotransferases; Pyrimidine Nucleosides; Pyrimidines; Research; Thymidine; Thymine; Uracil

1964
THE ROLE OF DEOXYRIBONUCLEIC ACID IN THE SYNTHESIS OF ROUS SARCOMA VIRUS.
    Virology, 1964, Volume: 22

    Topics: Animals; Avian Sarcoma Viruses; Colchicine; Dactinomycin; DNA; DNA, Neoplasm; DNA, Viral; Fluorouracil; Neoplasms; Nucleosides; Pharmacology; Poultry; Research; Rous sarcoma virus; Thymidine

1964
STUDIES ON THE REPLICATING POOL OF VIRAL DNA IN CELLS INFECTED WITH PSEUDORABIES VIRUS.
    Virology, 1964, Volume: 24

    Topics: Adenine; Antiviral Agents; Carbon Isotopes; Cesium; Deoxyribonucleases; DNA; DNA, Viral; Fluorouracil; Herpesviridae; Herpesvirus 1, Suid; Nucleosides; Pharmacology; Research; Simplexvirus; Thymidine; Tissue Culture Techniques; Virus Cultivation

1964
COMBINATION OF SURGERY AND CHEMOTHERAPY IN THE TREATMENT OF ORAL CANCER.
    American journal of surgery, 1964, Volume: 108

    Topics: DNA; DNA, Neoplasm; Drug Therapy; Fluorouracil; Humans; Methotrexate; Mouth Neoplasms; Neck Dissection; Neoplasms; Surgical Procedures, Operative; Thymidine

1964
SUBSTRATE SPECIFICITY AND INDUCTION OF THYMIDINE PHOSPHORYLASE IN ESCHERICHIA COLI.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Chloramphenicol; Escherichia coli; Fluorouracil; Glucosyltransferases; Nucleosides; Pharmacology; Research; Substrate Specificity; Thymidine; Thymidine Phosphorylase; Uracil

1964
EFFECTS OF URACIL MUSTARD ON IN VIVO INCORPORATION OF PRECURSORS INTO NUCLEIC ACIDS OF THE WALKER TUMOR.
    Texas reports on biology and medicine, 1964, Volume: 22

    Topics: Animals; Carcinoma; Carcinoma 256, Walker; DNA; DNA, Neoplasm; Fluorouracil; Kinetics; Metabolism; Nitrogen Mustard Compounds; Nucleic Acids; Pharmacology; Rats; Research; RNA; RNA, Neoplasm; Thymidine; Uracil Mustard

1964
UPTAKE AND INCORPORATION OF THYMINE, THYMIDINE, URACIL, URIDINE, AND 5-FLUOROURACIL INTO THE NUCLEIC ACIDS OF BACILLUS SUBTILIS.
    Journal of bacteriology, 1965, Volume: 89

    Topics: Bacillus subtilis; Carbon Isotopes; DNA; DNA, Bacterial; Fluorouracil; Metabolism; Nucleosides; Research; RNA; RNA, Bacterial; Thymidine; Thymine; Tritium; Uracil; Uridine

1965
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. I. SUSPENSION CELL CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA.
    Cancer research, 1965, Volume: 25

    Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Floxuridine; Fluorouracil; Glycine; Liver Neoplasms; Liver Neoplasms, Experimental; Metabolism; Methotrexate; Mutation; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Pyrimidines; Rats; Research; Serine; Thymidine; Thymidine Kinase; Thymine; Tissue Culture Techniques; Toxicology; Uracil

1965
EVIDENCE FOR CYTOPLASMIC DNA IN ROOT CELLS OF NICOTIANA.
    The Journal of cell biology, 1965, Volume: 24

    Topics: Autoradiography; Cell Nucleus; Cytoplasm; Dactinomycin; Deoxyribonucleases; DNA; DNA Replication; Fluorouracil; Kinetics; Metabolism; Mitomycin; Mitomycins; Nicotiana; Nucleosides; Research; Ribonucleases; RNA; Thymidine; Tritium

1965
AMINO ACID REGULATION OF BACTERIOPHAGE RNA SYNTHESIS.
    Journal of molecular biology, 1965, Volume: 12

    Topics: Amino Acids; Bacteriophages; Chloramphenicol; Coliphages; Fluorouracil; Metabolism; Molecular Biology; Mutation; Pharmacology; Research; RNA; RNA, Viral; Thymidine

1965
Effects of 5-fluorodeoxyuridine and related halogenated pyrimidines on the sand-dollar embryo.
    The Journal of biophysical and biochemical cytology, 1960, Volume: 7

    Topics: Cytidine; DNA; Female; Floxuridine; Fluorouracil; Humans; Orotic Acid; Pregnancy; Pyrimidines; Thymidine; Thymine; Uridine

1960
Phytohemagglutinin inhibits lymphoid tumor growth in vitro and in vivo.
    Leukemia & lymphoma, 2003, Volume: 44, Issue:10

    Topics: Animals; Annexin A5; Antimetabolites, Antineoplastic; Apoptosis; Cell Cycle; Drug Combinations; Drug Synergism; Fluorouracil; In Vitro Techniques; Lymphoma, B-Cell; Lymphoma, T-Cell; Male; Mice; Mice, SCID; Phytohemagglutinins; Thymidine; Tumor Cells, Cultured

2003
Overproduction of thymidine by recombinant brevibacterium helvolum amplified with thymidine monophosphate phosphohydrolase gene from bacteriophage PBS2.
    Biotechnology letters, 2004, Volume: 26, Issue:4

    Topics: Bacterial Proteins; Bacteriophages; Brevibacterium; Chromatography, High Pressure Liquid; Cloning, Molecular; Drug Resistance, Bacterial; Fermentation; Fluorouracil; Hydroxyurea; Mutation; Nucleotidases; Phosphoric Monoester Hydrolases; Plasmids; Recombinant Proteins; Thymidine; Thymidine Monophosphate; Trimethoprim

2004
A novel polypyrimidine antitumor agent FdUMP[10] induces thymineless death with topoisomerase I-DNA complexes.
    Cancer research, 2005, Jun-01, Volume: 65, Issue:11

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Death; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; DNA, Single-Stranded; Drug Screening Assays, Antitumor; Fluorodeoxyuridylate; Fluorouracil; Leukemia P388; Mice; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Topoisomerase I Inhibitors

2005
Elevation of radiolabelled thymidine uptake in RIF-1 fibrosarcoma and HT29 colon adenocarcinoma cells after treatment with thymidylate synthase inhibitors.
    European journal of nuclear medicine and molecular imaging, 2006, Volume: 33, Issue:9

    Topics: Adenocarcinoma; Biological Transport, Active; Cell Line, Tumor; Cell Survival; Cisplatin; Colonic Neoplasms; Enzyme Inhibitors; Fibrosarcoma; Fluorouracil; HT29 Cells; Humans; Quinazolines; Radionuclide Imaging; Radiopharmaceuticals; Thymidine; Thymidylate Synthase; Time Factors; Tritium

2006
Trypanosoma brucei: a survey of pyrimidine transport activities.
    Experimental parasitology, 2006, Volume: 114, Issue:2

    Topics: Animals; Antimetabolites; Biological Transport; Cytidine; Cytosine; Female; Fluorouracil; Parasitic Sensitivity Tests; Pyrimidines; Rats; Rats, Wistar; Thymidine; Thymine; Trypanocidal Agents; Trypanosoma brucei brucei; Uridine

2006
The role of thymidine phosphorylase and uridine phosphorylase in (fluoro)pyrimidine metabolism in peripheral blood mononuclear cells.
    The international journal of biochemistry & cell biology, 2006, Volume: 38, Issue:10

    Topics: Cells, Cultured; Floxuridine; Fluorouracil; Humans; Inhibitory Concentration 50; Leukocytes, Mononuclear; Pyrimidines; RNA; Substrate Specificity; Thymidine; Thymidine Phosphorylase; Uridine Phosphorylase

2006
Altered deoxyuridine and thymidine in plasma following capecitabine treatment in colorectal cancer patients.
    British journal of clinical pharmacology, 2007, Volume: 63, Issue:1

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Deoxyuridine; Female; Fluorouracil; Humans; Male; Thymidine

2007
Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect.
    The Journal of clinical investigation, 2006, Volume: 116, Issue:10

    Topics: Animals; Animals, Newborn; Bone Marrow Cells; Cell Cycle; Cell Proliferation; Chemokine CXCL12; Chemokines, CXC; Fluorouracil; Gene Expression; Graft Survival; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Hematopoietic System; Hyaluronan Receptors; Integrin alpha4; Liver; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-kit; Receptors, CXCR4; Thymidine; Vascular Cell Adhesion Molecule-1

2006
Mechanisms of acquired chemoresistance to 5-fluorouracil and tomudex: thymidylate synthase dependent and independent networks.
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:6

    Topics: Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Fluorouracil; Humans; NF-kappa B; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2007
Influence of dTMP on the phenotypic appearance and intracellular persistence of Staphylococcus aureus.
    Infection and immunity, 2008, Volume: 76, Issue:4

    Topics: Anti-Bacterial Agents; Cell Line; Cystic Fibrosis; Dihydropteroate Synthase; Fluorouracil; Folic Acid Antagonists; Humans; Lung; Phenotype; Staphylococcus aureus; Thymidine; Trimethoprim, Sulfamethoxazole Drug Combination; Uridine

2008
Cannabinoid receptor-independent cytotoxic effects of cannabinoids in human colorectal carcinoma cells: synergism with 5-fluorouracil.
    Cancer chemotherapy and pharmacology, 2009, Volume: 63, Issue:4

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antioxidants; Cannabinoid Receptor Antagonists; Cannabinoids; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cyclic AMP; Dronabinol; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Fatty Acids, Unsaturated; Fluorouracil; Humans; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidative Stress; Piperidines; Pyrazoles; Receptors, Cannabinoid; Thymidine; Tumor Cells, Cultured

2009
[18F]FDG and [18F]FLT uptake in human breast cancer cells in relation to the effects of chemotherapy: an in vitro study.
    British journal of cancer, 2008, Aug-05, Volume: 99, Issue:3

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Doxorubicin; Fluorodeoxyglucose F18; Fluorouracil; Humans; Paclitaxel; Thymidine; Thymidine Kinase

2008
Novel opportunities for thymidylate metabolism as a therapeutic target.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:9

    Topics: Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Computational Biology; DNA Damage; Drug Design; Drug Resistance, Neoplasm; Fluorouracil; Humans; Immunohistochemistry; Pyrophosphatases; Reproducibility of Results; Thymidine

2008
Limits to thymidylate synthase and TP53 genes as predictive determinants for fluoropyrimidine sensitivity and further evidence for RNA-based toxicity as a major influence.
    Cancer research, 2009, Feb-01, Volume: 69, Issue:3

    Topics: Alleles; Antimetabolites, Antineoplastic; Base Sequence; Cell Line, Tumor; Colorectal Neoplasms; Fluorouracil; Genes, p53; HCT116 Cells; Humans; Molecular Sequence Data; Mutation; RNA, Messenger; RNA, Neoplasm; Thymidine; Thymidylate Synthase; Uridine; Yeasts

2009
Effects of 5-FU on DNA synthesis and cytotoxicity of human lymphocytes induced by IL-2, TGF-beta3 and PGE2.
    Anticancer research, 2009, Volume: 29, Issue:10

    Topics: Cell Cycle; Cells, Cultured; Culture Media; Cytotoxicity, Immunologic; Dinoprostone; DNA; Drug Interactions; Fluorouracil; Humans; Interleukin-2; Lymphocyte Activation; Lymphocytes; Receptors, Interleukin-2; Thymidine; Transforming Growth Factor beta3

2009
Imaging colon cancer response following treatment with AZD1152: a preclinical analysis of [18F]fluoro-2-deoxyglucose and 3'-deoxy-3'-[18F]fluorothymidine imaging.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Mar-01, Volume: 17, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Dideoxynucleosides; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Fluorouracil; HCT116 Cells; Humans; Immunoblotting; Ki-67 Antigen; Methotrexate; Mice; Mice, Nude; Organophosphates; Positron-Emission Tomography; Quinazolines; Radiopharmaceuticals; Thymidine; Thymidine Kinase; Xenograft Model Antitumor Assays

2011
UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.
    Nucleic acids research, 2011, Volume: 39, Issue:19

    Topics: Animals; Cell Cycle; Cell Line, Tumor; DNA; DNA Damage; DNA Repair; Endodeoxyribonucleases; Floxuridine; Fluorouracil; Gene Knockdown Techniques; Humans; Mice; MutS Homolog 2 Protein; RNA; Thymidine; Thymine DNA Glycosylase; Uracil-DNA Glycosidase; Uridine

2011
Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice.
    Nucleic acids research, 2012, Volume: 40, Issue:13

    Topics: Animals; beta-Galactosidase; Cell Line; DNA Repair; Fibroblasts; Fluorouracil; Gene Targeting; Genetic Predisposition to Disease; Longevity; Mice; Mice, Inbred C57BL; Mice, Knockout; MutS Homolog 2 Protein; Neoplasms, Experimental; Pentoxyl; Thymidine; Uracil-DNA Glycosidase

2012
Low-temperature NMR studies on the geometry of base pairs involving 5-substituted uracil derivatives.
    The journal of physical chemistry. B, 2013, May-02, Volume: 117, Issue:17

    Topics: Adenosine; Base Pairing; Bromouracil; Cold Temperature; Fluorouracil; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Thymidine; Uracil; Uridine

2013
Attenuation of nucleoside and anti-cancer nucleoside analog drug uptake in prostate cancer cells by Cimicifuga racemosa extract BNO-1055.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2013, Nov-15, Volume: 20, Issue:14

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Bromodeoxyuridine; Cell Line; Cell Proliferation; Cimicifuga; Deoxycytidine; Dose-Response Relationship, Drug; Equilibrative Nucleoside Transport Proteins; Fluorouracil; Gemcitabine; Humans; Male; Nucleosides; Phytotherapy; Plant Extracts; Prostate; Prostatic Neoplasms; RNA, Small Interfering; Saponins; Thymidine; Vidarabine

2013
Kinetics and mechanistic study of competitive inhibition of thymidine phosphorylase by 5-fluoruracil derivatives.
    Colloids and surfaces. B, Biointerfaces, 2016, Apr-01, Volume: 140

    Topics: Antimetabolites; Binding Sites; Binding, Competitive; Dimyristoylphosphatidylcholine; Escherichia coli; Escherichia coli Proteins; Fluorouracil; Kinetics; Liposomes; Molecular Docking Simulation; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Thymidine; Thymidine Phosphorylase

2016
Inhibition of thymidylate synthase affects neural tube development in mice.
    Reproductive toxicology (Elmsford, N.Y.), 2018, Volume: 76

    Topics: Animals; Apoptosis; Cell Proliferation; Deoxyuracil Nucleotides; Embryonic Development; Fluorouracil; Mice, Inbred C57BL; Neural Tube; Neural Tube Defects; Neuroepithelial Cells; Thymidine; Thymidylate Synthase

2018
Thymidine Metabolism as a Confounding Factor for 3'-Deoxy-3'-
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2018, Volume: 59, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Artifacts; Biological Transport; Cell Transformation, Neoplastic; Colorectal Neoplasms; Dideoxynucleosides; Diffusion Magnetic Resonance Imaging; Female; Fluorouracil; HCT116 Cells; Humans; Leucovorin; Mice; Organoplatinum Compounds; Thymidine

2018