fluorouracil and thiouracil

fluorouracil has been researched along with thiouracil in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199013 (65.00)18.7374
1990's0 (0.00)18.2507
2000's4 (20.00)29.6817
2010's3 (15.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Beck, CF; Howlett, GJ1
Arenhövel, C; Golovinsky, E; Schuster, G1
Harbers, E1
Beridze, TG; Cherkashina, NA; Odintsova, MS; Sissakian, NM1
Bronchart, R; De Barsy, T; Deltour, R1
Lohmann, W; Penka, V1
Kaiser, II1
Hirai, T; Nomura, A; Taniguchi, T1
Thiry, L1
Dubash, PJ; Rege, DV1
Bunker, JE; Keller, F; Tyrrill, AR1
ANDERSON, EP; BROCKMAN, RW1
WU, C1
Al Safarjalani, ON; El Kouni, MH; Naguib, FN; Rais, RH; Schinazi, RF; Shi, J; Zhou, XJ1
Al Safarjalani, ON; el Kouni, MH; Naguib, FN; Rais, R; Schinazi, RF; Shi, J1
Camoutsis, C; Dalezis, P; Geromichalos, GD; Geromichalou, E; Grivas, AA; Kontos, M; Papageorgiou, A; Trafalis, DT; Tsigris, C1
Al Safarjalani, ON; el Kouni, MH; Naguib, FN; Rais, R1
Elferich, J; Forquer, I; Riscoe, MK; Shinde, U; Soysa, R; Ullman, B; Wilson, ZN; Yates, PA1

Reviews

1 review(s) available for fluorouracil and thiouracil

ArticleYear
BIOCHEMISTRY OF CANCER (METABOLIC ASPECTS).
    Annual review of biochemistry, 1963, Volume: 32

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Azaguanine; Azaserine; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Floxuridine; Fluorouracil; Folic Acid; Glutamine; Leukemia L1210; Mercaptopurine; Methotrexate; Mitomycin; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Puromycin; Pyrimidines; Research; RNA; RNA, Neoplasm; Thioguanine; Thiouracil

1963

Other Studies

19 other study(ies) available for fluorouracil and thiouracil

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
The nature of the miscoding caused by growth in the presence of 2-thiouracil.
    Journal of molecular biology, 1977, Mar-25, Volume: 111, Issue:1

    Topics: Bacterial Proteins; Codon; Escherichia coli; Fluorouracil; Mutation; Phenotype; RNA, Bacterial; RNA, Messenger; Salmonella typhimurium; Thiouracil; Uracil

1977
Analogues of pyrimidine base precursors as antiphytoviral agents.
    Antiviral research, 1987, Volume: 7, Issue:3

    Topics: Antiviral Agents; Cycloheximide; Fluorouracil; Orotic Acid; Plant Viruses; Thiouracil; Triazines; Virus Replication

1987
[The function of nucleic acids in cellular metabolism].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1966, Volume: 253, Issue:1

    Topics: DNA; Fluorouracil; In Vitro Techniques; Mercaptopurine; Nucleic Acids; RNA; Thioguanine; Thiouracil

1966
The effect of nucleic acid synthesis inhibitors on the chlorophyll formation by etiolated bean leaves.
    Biochemical and biophysical research communications, 1966, Jun-13, Volume: 23, Issue:5

    Topics: Azaguanine; Chlorophyll; Dactinomycin; Floxuridine; Fluorouracil; In Vitro Techniques; Mitomycins; Plants, Edible; Thiouracil; Thymidine; Uridine

1966
Study of nucleolar vacuolation and RNA synthesis in embryonic root cells of Zea mays.
    Journal of cell science, 1974, Volume: 16, Issue:1

    Topics: Autoradiography; Cell Nucleolus; Dactinomycin; Fluorouracil; Inclusion Bodies; Microscopy, Electron; Plants; RNA, Ribosomal; Temperature; Thiouracil; Tritium; Uridine; Zea mays

1974
Influence of metal ions on systems of dimethylsulfoxide-uracil-derivatives: NMR investigations.
    Biophysik, 1973, Volume: 10, Issue:3

    Topics: Barbiturates; Bromouracil; Cobalt; Copper; Deuterium; Dimethyl Sulfoxide; Fluorouracil; Ions; Iron; Ligands; Magnetic Resonance Spectroscopy; Metals; Nickel; Silver; Thiouracil; Uracil; Zinc

1973
Studies on 5-fluorouracil-containing RNA. II. Gross reduction of 4-thiouracil in fluorouracil-containing tRNA from Escherichia coli.
    Biochimica et biophysica acta, 1969, Jun-17, Volume: 182, Issue:2

    Topics: Benzoates; Chemical Phenomena; Chemistry; Cytosine; Escherichia coli; Fluorouracil; Mercury; Oxidation-Reduction; RNA, Bacterial; RNA, Transfer; Spectrophotometry; Thiouracil; Ultraviolet Rays

1969
The structure of tobacco mosaic virus from base analogue treated tobacco leaves.
    Japanese journal of microbiology, 1969, Volume: 13, Issue:2

    Topics: Alkalies; Azaguanine; Carbon Isotopes; Cellulose; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Fluorouracil; Nicotiana; Plants, Toxic; RNA, Viral; Thiouracil; Tobacco Mosaic Virus

1969
Viruses grown in the presence of base analogs: specific alteration of susceptibility to inactivation by radiations, mutagens, and protodyes.
    Virology, 1966, Volume: 28, Issue:4

    Topics: Arboviruses; Coloring Agents; Fluorouracil; Guanine; Hydroxylamines; In Vitro Techniques; Light; Methylene Blue; Newcastle disease virus; Nitrites; Nucleic Acids; Nucleosides; Photosensitivity Disorders; Purines; Sulfates; Thiouracil; Ultraviolet Rays; Uracil; Uridine; Virus Cultivation; Xanthine Oxidase

1966
Chlorophyll formation in Euglena gracilis var. bacillaris: interference by analogues of purines, pyrimidines and amino acids.
    Journal of general microbiology, 1967, Volume: 48, Issue:2

    Topics: Azaguanine; Chlorophyll; Citric Acid Cycle; Ethionine; Euglena; Fluorouracil; Mercaptopurine; Methionine; Purines; Thiouracil; Uracil

1967
A direct synthesis of 1-beta-D-arabinofuranosyl-5-fluorocytosine.
    Journal of medicinal chemistry, 1967, Volume: 10, Issue:5

    Topics: Antineoplastic Agents; Arabinose; Cytosine; Fluorine; Fluorouracil; Nucleosides; Pyrimidines; Thiouracil; Uracil

1967
GLUTAMINE SYNTHETASE. 3. FACTORS CONTROLLING ITS ACTIVITY IN THE DEVELOPING RAT.
    Archives of biochemistry and biophysics, 1964, Jul-20, Volume: 106

    Topics: Amino Acids; Ammonium Compounds; Animals; Animals, Newborn; Azaguanine; Brain; Dactinomycin; Ethionine; Fluorouracil; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Humans; Hydrocortisone; Kidney; Lactates; Ligases; Liver; Male; Nucleosides; Pharmacology; Phenylalanine; Puromycin; Quaternary Ammonium Compounds; Rats; Research; Testis; Thiouracil; Thyroxine

1964
5-(Phenylthio)acyclouridine: a powerful enhancer of oral uridine bioavailability: relevance to chemotherapy with 5-fluorouracil and other uridine rescue regimens.
    Cancer chemotherapy and pharmacology, 2005, Volume: 55, Issue:6

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Biological Availability; Body Weight; Female; Fluorouracil; Mice; Mice, Inbred Strains; Thiouracil; Uracil; Uridine; Uridine Phosphorylase

2005
Modulation of 5-fluorouracil host-toxicity and chemotherapeutic efficacy against human colon tumors by 5-(Phenylthio)acyclouridine, a uridine phosphorylase inhibitor.
    Cancer chemotherapy and pharmacology, 2006, Volume: 58, Issue:5

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorouracil; Humans; Male; Mice; Mice, SCID; Survival Analysis; Thiouracil; Uridine; Uridine Phosphorylase; Xenograft Model Antitumor Assays

2006
In silico/in vitro study of hybrid D-modified steroidal alkylator anticancer activity using uridine phosphorylase as target protein.
    Anticancer research, 2011, Volume: 31, Issue:3

    Topics: Alkylating Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Computational Biology; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Ligands; Models, Molecular; Molecular Targeted Therapy; Neoplasm Proteins; Steroids; Thermodynamics; Thiouracil; Uridine Phosphorylase

2011
Potent combination therapy for human breast tumors with high doses of 5-fluorouracil: remission and lack of host toxicity.
    Cancer chemotherapy and pharmacology, 2012, Volume: 69, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Female; Fluorouracil; Humans; Mice; Mice, SCID; Thiouracil; Uridine; Xenograft Model Antitumor Assays

2012
Substrate inhibition of uracil phosphoribosyltransferase by uracil can account for the uracil growth sensitivity of Leishmania donovani pyrimidine auxotrophs.
    The Journal of biological chemistry, 2013, Oct-11, Volume: 288, Issue:41

    Topics: Cations, Divalent; Chromatography, Gel; Enzyme Stability; Feedback, Physiological; Fluorouracil; Hydrogen-Ion Concentration; Kinetics; Leishmania donovani; Mutation; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Protein Multimerization; Protozoan Proteins; Pyrimidines; Recombinant Proteins; Spectrophotometry; Substrate Specificity; Temperature; Thiouracil; Uracil

2013