fluorouracil has been researched along with tegafur in 1372 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 456 (33.24) | 18.7374 |
| 1990's | 213 (15.52) | 18.2507 |
| 2000's | 399 (29.08) | 29.6817 |
| 2010's | 273 (19.90) | 24.3611 |
| 2020's | 31 (2.26) | 2.80 |
| Authors | Studies |
|---|---|
| Hashimoto, S; Moriyama, A; Suzue, T; Unemi, N; Yasumoto, M | 1 |
| Hashimoto, S; Marunaka, T; Yamawaki, I; Yasumoto, M | 1 |
| Benjamin, RS; Lin, AJ; Loo, TL; Rao, PN | 1 |
| Ferguson, PW; Holshouser, MH; Shipp, AM | 1 |
| Antonini, I; Cosby, LA; Kirkpatrick, DL; Lin, TS; Sartorelli, AC; Shiba, DA; Wang, L | 1 |
| Cook, AF; Holman, MJ; Kramer, MJ | 1 |
| Hronowski, LJ; Szarek, WA | 1 |
| Levin, VA | 1 |
| Fukawa, K; Haga, S; Hiiragi, M; Irino, O; Kametani, T; Kigasawa, K; Nagamatsu, Y; Nakayama, M; Nishimura, N; Okada, T; Sugi, H; Taguchi, A; Wakisaka, K; Yamamoto, T | 1 |
| Fujiwara, H; Kai, J; Masuda, T; Nakamura, K; Ueda, I | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Chen, IC; Chen, MC; Hsu, KC; Lai, MJ; Li, YH; Liao, YH; Lien, ST; Liou, JP; Liu, YM; Pan, SL; Wu, WC | 1 |
| Han, H; Qi, XR; Shen, L; Tang, HF; Xu, QZ; Yang, WS; Yi, YH; Yuan, CH | 1 |
| Gilev, AP; Khagi, KhB; Meĭren, DV; Sniedze, TN; Urbanovich, EL | 1 |
| Akiyoshi, H; Fujii, S; Minato, Y; Okuda, H; Toide, H | 1 |
| Mayr, AC | 1 |
| Asserkritova, IV; Garin, AM; Lichinitser, MR; Perevodchikova, NI; Vaarik, GKh | 1 |
| Drago, JR; Gershwin, ME; Goldman, LB; Maurer, RE | 1 |
| Lelieveld, P; Pantarotto, C; Salmona, M; Spreafico, F; van Putten, LM | 1 |
| Hiraiwa, K; Ichikawa, H; Kaneda, T | 1 |
| Soejima, S | 1 |
| Hashimoto, S; Ueda, S; Yamashita, J; Yasumoto, M | 1 |
| Pogosiants, EE; Sokova, OI; Volgareva, GM | 3 |
| Ariyama, J; Izumi, T; Kurihara, M; Miyasaka, K; Shirakabe, H | 1 |
| Bodey, GP; Issell, BF; Valdivieso, M | 1 |
| Hobara, N; Nagashima, H; Watanabe, A | 1 |
| Hobara, N; Watanabe, A | 2 |
| Akao, T; Fujimoto, S; Itoh, B; Koshizuka, I; Koyano, K | 1 |
| Benvenuto, JA; Loo, TL; Lu, K | 1 |
| Borisov, VI; Buracheskaia, NV; Karam, M; Lipatov, AM; Shkarenkov, VA | 1 |
| Bukharova, IK; Golubeva, VA; Osipov, NE | 1 |
| Sokova, OI; Volgareva, GM | 2 |
| Chao, LY; Saunders, PP | 1 |
| Kucerová, E; Tománková, H | 1 |
| Gilev, AP; Kozhukhov, AN; Meĭren, DV | 1 |
| Fukawa, O; Hori, S; Mori, T; Sato, T | 1 |
| Aledseev, VM; Blokhina, NG; Smolianskaia, AZ; Sokolova, VD | 1 |
| Misawa, S; Ohkuma, S; Sawai, K; Sonoda, Y; Takino, T | 1 |
| Bedikian, A; Bodey, GP; Burgess, MA; Hersh, EM; Mavligit, GM; Rodriguez, V; Valdivieso, M | 1 |
| Benjamin, RS; Hall, SW; Valdivieso, M | 1 |
| Baker, L; Buroker, T; McKenzie, M; Miller, A; Samson, M; Vaitkevicius, VK | 1 |
| Diggs, CH; Smyth, AC; Wiernik, PH | 1 |
| Andrzejewski, D; Brukwinski, W; Burke, M; Godefroi, VC; Hills, EB; Horwitz, JP; O'Leary, IA | 1 |
| Au, JL; Sadée, W; Wu, AT | 1 |
| Dovzhanskiĭ, SI; Suvorov, AP | 1 |
| Hikasa, Y; Kato, T; Kojima, T; Nomura, Y; Shioda, R | 1 |
| Ogawa, M | 1 |
| Baker, L; Buroker, T; DeMattia, M; Dindogru, A; Groth, C; Vaitkevicius, VK; Wojtaszak, B | 1 |
| Romanenko, NV; Smolianskaia, AZ | 1 |
| Honda, H | 1 |
| Shioda, R | 1 |
| Benjamin, RS; Benvenuto, JA; Hall, SW; Loo, TL; Lu, K | 1 |
| Kinami, Y; Miyazaki, H; Odagiri, S; Shinmura, K | 1 |
| Horio, T; Ikai, K; Murai, T | 1 |
| Benjamin, RS; Benvenuto, JA; Hall, SW; Loo, TL; Lu, K; McKelvey, EM | 1 |
| Sokova, OI | 1 |
| Babaian, LA; Borisov, VI; Perevodchikova, NI; Vaarik, KhM; Voznyĭ, EK | 1 |
| Hashimoto, S; Yamashita, J; Yasumoto, M | 1 |
| Au, JL; Friedman, MA; Sadée, W; Wu, AT | 1 |
| Cohen, AM; Dethlefsen, LA; Gray, JW; Pallavicini, MG | 1 |
| Izumi, T; Kamano, T; Kishino, H; Kurihara, M; Maruyama, T; Minakami, T; Miyasaka, K; Shirakabe, H; Yamaya, F | 1 |
| Hattori, T; Koh, T; Nakano, A; Niimoto, M; Nishimawari, K; Oride, M; Takiyama, W | 1 |
| Dalgat, DM | 1 |
| Buroker, T; Groppe, C; Guy, G; Heilbrun, L; Hoogstraten, B; McCracken, J; Padilla, F; Quagliana, J; Vaitkevicius, VK | 1 |
| Benvenuto, JA; Caprioli, RM; Farquhar, D; Liehr, JG; Loo, TL; Winkler, T | 1 |
| Fujimoto, S; Ishigami, H; Itoh, K; Kimura, K; Minami, T; Miyazaki, M | 1 |
| Hartwich, G | 2 |
| Fujii, S; Ikenaka, K; Kitano, S; Shirasaka, T | 1 |
| Hahn, S; Kim, DS | 1 |
| Blumenschein, GR; Bodey, GP; Burgess, MA; Buzdar, AU; Gutterman, JU; Hersh, EM; Hortobagyi, GN; Livingston, RB; Tashima, CK; Valdivieso, M | 1 |
| Belt, RJ; Stephens, R | 1 |
| Au, JL; Sadée, W | 4 |
| Denine, EP; Giles, HD; Harrison, SD | 1 |
| Arnold, H; Drings, P; Geldmacher, J; Hartwich, G; Kredel, L; Mayer, M; Neidhardt, B; Queisser, W; Rösch, W; Schaefer, J; von Oldershausen, HF; Wahrendorf, J | 1 |
| Belitskiĭ, GA; Bukhman, VM; Konopleva, IA | 1 |
| Haller, DG; Hoth, DF; MacDonald, JS; Rosenoff, S; Schein, PS; Smythe, T; Woolley, PV | 1 |
| Hara, Y | 1 |
| Benjamin, RS; Bodey, GP; Hall, SW; Murphy, WK; Valdivieso, M | 1 |
| Benjamin, RS; Blumenschein, GR; Bodey, GP; Buzdar, AU; Gutterman, JU; Hortobagyi, GN; Krutchik, AN; Tashima, CK; Yap, HY | 1 |
| Facchinetti, T; Fanelli, R; Filippeschi, S; Pantarotto, C; Salmona, M; Spreafico, F | 1 |
| Emmerling, DC; Freudenthal, RI | 1 |
| Kato, Y; Kawashima, Y; Kitade, F; Okada, K; Okajima, K; Osawa, N; Sakuramoto, K; Sekimoto, T; Yagi, A; Yamada, S | 1 |
| Voznyĭ, EK | 1 |
| Apinis, TA; Gilev, AP; Meĭrena, DV; Zhuk, RA; Zilbere, AM | 1 |
| Blokhin, NN | 1 |
| Garibjanian, BT; Gaston, MR; Goldin, A; Houchens, DP; Johnson, RK; Kline, I; Syrkin, AB | 1 |
| Gang, M; Garibjanian, BT; Goldin, A; Johnson, RK; Kline, I; Vadlamudi, S; Venditti, JM | 1 |
| Baumanis, EA; Brusovanik, VI; Iablonovskaia, LIa; Kalnina, IE | 1 |
| Krusanova, NI; Kubatkina, EI; Potapov, SL; Sevast'ianova, LA; Vasil'eva, NN | 1 |
| Aoki, K; Nose, H; Okada, S; Okazaki, N; Yoshimori, M | 1 |
| Abe, R; Arima, S; Fukuyama, N; Hisatsugu, T; Kuroda, Y; Nakamura, Y; Ohkuma, R; Ohsato, K; Yamamoto, H; Yamanouchi, A | 1 |
| Kato, T; Kitaichi, K; Koda, A; Mori, H; Sakamoto, O | 1 |
| Inaba, S; Kawai, K; Kondo, Y; Ogino, A; Tsuchiya, K; Ueda, Y; Umeda, T | 1 |
| Hosoda, Y; Miyakawa, T; Okamura, H; Okubo, S; Oshima, Y; Shiina, E; Shimizu, M; Suda, Y; Tokura, Y; Uchida, K | 1 |
| Baba, E; Fukushima, T; Kataoka, A; Kondo, Y; Masuko, H; Ohmori, K; Ohsawa, S; Sawaguchi, Y; Shiroto, H; Takahashi, T | 1 |
| Harada, M; Koga, K; Miura, I; Nishitani, H; Umeno, Y | 1 |
| Oguro, Y | 1 |
| Aziz Rani, A; Chudahman, M; Dharmika, D; Ismail Ali, A; Simadibrata, R | 1 |
| Emi, Y; Kohnoe, S; Maehara, Y; Sugimachi, K; Takahashi, I; Yoshida, M | 1 |
| Kanazawa, K; Kon, T; Konishi, F; Kotake, K; Koyama, Y; Namba, M; Nara, K; Nozawa, K; Shida, S; Umemoto, S | 1 |
| Baba, H; Emi, Y; Kohnoe, S; Kusumoto, H; Maehara, Y; Sugimachi, K; Takahashi, I; Yoshida, M | 1 |
| Hatta, Y; Kanda, M; Kikuchi, H; Kunimura, T; Miura, K; Morohoshi, T; Sato, M; Taguchi, S | 1 |
| Kusumoto, T; Miyagi, M; Nakashima, T | 1 |
| Kanamaru, R; Wakui, A | 1 |
| Akagi, M; Kakegawa, T; Maehara, Y; Shimazu, H; Sugimachi, K; Tomita, M | 1 |
| Hirano, T; Ifuku, M; Ishikawa, H; Kusano, H; Nakagoe, T; Shimizu, T; Tomita, M | 1 |
| Akino, H; Isomatu, Y; Kanimoto, Y; Miwa, Y; Okada, K; Suzuki, Y | 1 |
| Shparyk, IaV | 1 |
| Gotoh, M; Katsura, Y; Nomoto, K; Noritake, M; Shinomiya, N; Tsuru, S | 1 |
| Bosse, C; Czejka, MJ; Fogl, U; Jäger, W; Schüller, J | 1 |
| Anai, H; Emi, Y; Kohnoe, S; Maehara, Y; Sakaguchi, Y; Sugimachi, K | 1 |
| Fujita, K; Munakata, A | 1 |
| Mitsuyama, M; Nomoto, K; Yokokura, T; Yoshikai, Y | 1 |
| Adachi, S; Akaza, H; Ishitsuka, H; Kanazawa, K; Miwa, M; Nitta, K; Sekiguchi, F; Tokita, H | 1 |
| Akazai, Y; Fuchimoto, S; Iwagaki, H; Matsubara, N; Orita, K; Shiiki, S; Watanabe, T | 1 |
| Bando, Y; Furukawa, K; Iseki, T; Kawahito, M; Komi, N; Kunitomo, K; Miura, M; Morioka, K; Sasaki, K | 1 |
| Hayashi, H; Hazama, S; Murakami, T; Oka, M; Suzuki, T | 1 |
| Kawabata, N; Nakashima, T; Ohno, H; Yano, K | 1 |
| Ban, Y; Ito, Y; Kawada, Y; Kuriyama, M; Maeda, S; Shinoda, I; Tada, K; Takahashi, Y; Takeuchi, T; Yamamoto, N | 1 |
| Furusawa, M; Kakeji, Y; Maehara, Y; Sugimachi, K; Tomoda, H; Tsujitani, S; Watanabe, A | 1 |
| Fukuoka, M; Kudoh, S; Kusunoki, Y; Masuda, N; Matsui, K; Negoro, S; Ryu, S; Sakai, N; Takada, M; Takifuji, S | 1 |
| Camps, C; Godes, M; Soler, JJ | 1 |
| Chen, JT; Fujimoto, I; Hamada, T; Hasumi, K; Hirai, Y; Nakayama, K; Shimizu, Y; Teshima, H; Yamauchi, K; Yokosuka, K | 1 |
| Horiuchi, M; Kaneko, S; Komiyama, S; Miyake, H; Ogasawara, H; Sugita, M; Tsukuda, M | 1 |
| Amemiya, A; Emoto, T; Fujii, M; Han, N; Itou, A; Iwasaki, T; Tsujimura, T; Yoshikawa, K | 1 |
| Arai, K; Awane, Y; Kitamura, M; Miyashita, K | 1 |
| Katsuki, Y; Nishimura, A; Tsuji, Y; Yasuda, T | 1 |
| Fujita, M; Fujita, Y; Ota, J; Sakamoto, Y; Sugimoto, T; Taguchi, T | 1 |
| Houjo, K; Kawano, N; Moriya, Y; Sugihara, K | 1 |
| Hara, I; Kameyama, Y; Sakaki, Y; Tateishi, A; Yamada, N | 1 |
| Fukatsu, H; Hirata, N; Honda, N; Muramatsu, T; Segawa, A; Senda, H; Yamada, Y | 1 |
| Ishibiki, K; Kumai, K | 1 |
| Griffiths, JR; Maxwell, RJ; Prior, MJ | 1 |
| Imai, S; Morimoto, H; Nio, Y; Shiraishi, T; Tobe, T; Tseng, CC; Tsubono, M | 1 |
| Hirose, S; Kito, M; Takeshima, S; Urakami, K; Yoshida, S | 1 |
| Fujioka, T; Hasegawa, M; Ishikura, K; Koike, H; Kubo, T; Nomura, K; Okamoto, T; Tanji, S | 1 |
| Haruyama, K; Hase, S; Ishizawa, T; Katsura, Y; Niwa, K; Sameshima, T; Shimazu, H; Yamada, K; Yoshimura, A | 1 |
| Pedersen, H; Vestlev, PM | 1 |
| Brusentsov, NA; Glazkova, TIu; Iavorskaia, NP; Iurchenko, NIa | 1 |
| Cui, W; Wen, JQ | 1 |
| Hisamatsu, K; Ihara, T; Kirimoto, K; Matsuda, M; Nanba, K; Okamoto, E; Suemitsu, H; Yamada, M | 1 |
| Irie, G; Kamada, T; Matsuoka, Y; Shirato, H; Takamura, A; Tsuji, H; Tsujii, H | 1 |
| Ikeguchi, S; Muto, K; Namba, M; Shida, S | 1 |
| Asada, I; Furutani, M; Harada, T; Hayashi, S; Kitao, T; Matsushita, T; Shirosaki, H; Tanaka, T | 1 |
| Hieda, S; Ishihara, M; Noguchi, M; Sawaguchi, K; Ueno, N; Yabushita, H | 1 |
| Abe, O; Hattori, T; Kikuchi, K; Komi, N; Kondo, T; Kunii, Y; Nakajima, T; Nakazato, H; Taguchi, T; Tanabe, T | 1 |
| Anai, H; Kido, Y; Korenaga, D; Kusumoto, H; Kusumoto, T; Maehara, Y; Okamura, T; Sakaguchi, Y; Sugimachi, K | 1 |
| Barkanov, AI; Komov, DV; Roshchin, EM | 1 |
| Inoue, K; Mitani, K; Morishita, Y; Yamashita, K | 1 |
| Arima, S; Futami, K; Shimura, H; Toriya, H | 1 |
| Hosoi, H; Kitagawa, M; Sinmyo, K; Susaki, H; Suwa, H; Yamaguchi, K | 1 |
| Fujii, S; Fukushima, M; Shimamoto, Y; Shirasaka, T | 1 |
| Imai, S; Nio, Y; Ohgaki, K; Shiraishi, T; Tobe, T | 1 |
| Kimura, T; Kusama, S; Morioka, Y; Muto, T; Ogawa, N; Tomiyama, J | 1 |
| Furusawa, M; Hara, Y; Kono, A | 1 |
| Iwano, I; Kikuchi, Y; Kita, T; Kizawa, I; Kuki, E; Miyauchi, M; Oomori, K | 1 |
| Ono, M | 1 |
| Arima, S; Futami, K; Shimura, H; Yoshimura, S | 1 |
| Akashi, A; Hashimoto, J; Kawashima, Y; Matsumura, A; Minami, M; Mizuta, T; Nakagawa, K; Nakahara, K; Ohno, K; Takeda, S | 1 |
| Ono, T; Sawaki, S; Sudo, K; Tsukuda, M; Yanoma, S | 1 |
| Aoki, H; Ishibashi, M; Itoh, S; Kadowaki, A; Kogure, H; Tagaya, N; Tajima, T; Tajima, Y; Tomita, T | 1 |
| Hattori, T; Nakamura, T; Niimoto, M; Toge, T; Toi, M; Wada, T; Yamamoto, A | 1 |
| Ando, J; Kosaka, A; Sumiyoshi, K | 1 |
| Ahlgren, JD; Falchuk, SC; Macdonald, JS; Neefe, JR; Schein, PS; Smith, FP; Treat, J; Woolley, PV | 1 |
| Nishida, M; Sekiguchi, I; Suzuki, M; Tamada, T | 3 |
| Ito, Y; Matsuoka, S; Misawa, K; Nagafuchi, E; Nakajima, Y; Ogasawara, K; Sato, N; Uchino, J; Une, Y | 1 |
| Fujii, M; Hosoda, H; Inuyama, Y; Kohno, N; Takaoka, T; Tanaka, J | 1 |
| Suenaga, M | 1 |
| Ito, T; Izumi, T; Kurihara, M; Sasaki, J | 1 |
| Goto, S; Horiuchi, Y; Nagayo, T; Ohkita, T; Shimaji, T; Suga, S; Yokoyama, Y | 1 |
| Akine, Y; Egawa, S; Hijikata, J; Kajiura, Y; Kitagawa, T; Ogino, T; Tsukiyama, I; Yamashita, K | 1 |
| Koyama, H; Shiba, E | 1 |
| Baba, H; Kunimoto, T; Nitta, K; Sasaki, T; Takeuchi, M; Tanaka, T; Uehara, N | 1 |
| Wang, GT | 1 |
| Kato, T; Ota, K | 1 |
| Fujita, F; Fujita, M; Inaba, H; Sakamoto, Y; Shimozuma, K; Taguchi, T | 1 |
| Fujii, S | 1 |
| Eda, H; Fujimoto, K; Fukuda, H; Ishitsuka, H; Miwa, M | 1 |
| Hattori, T; Hirabayashi, N; Kirihara, Y; Niimoto, M; Nishiyama, M; Nosoh, Y; Saeki, T; Takagami, S | 1 |
| Hasegawa, H; Nakajima, Y; Obata, H; Ohnishi, K; Ohtsuki, T; Okazaki, N; Okuda, K; Tomimatsu, M | 1 |
| Fuse, M; Kondo, H; Mori, K; Ohta, Y; Onji, M; Yamashita, Y | 1 |
| Oguma, S; Ouchi, K; Owada, Y; Sakai, K; Sato, R; Sato, T | 1 |
| Imai, Y; Kawata, S; Minami, Y; Miyoshi, S; Noda, S; Saitoh, R; Tamura, S; Tarui, S | 1 |
| Inoue, S; Kato, H; Okada, Y; Takahashi, K; Yamanaka, A | 1 |
| Hanaue, H; Horie, F; Kitano, Y; Kurosawa, T; Miyakawa, S; Nemoto, A; Shikata, J | 2 |
| Aoki, N | 1 |
| Fujiwara, K; Inoue, K; Kaneshige, E; Kobashi, Y; Kono, I; Sekiba, K; Tanimura, T | 1 |
| Oiwa, T; Saito, H | 1 |
| Dokiya, T; Hashimoto, S; Kunieda, E; Miyamoto, H; Shigematsu, N; Tominaga, J | 1 |
| Furukawa, H; Iwanaga, T | 1 |
| Kobayashi, H; Obata, K; Sahashi, M | 1 |
| Bjerkeset, T; Fjøsne, HE | 1 |
| Kimura, M; Koida, T; Sugihara, S | 1 |
| Hoshi, A; Iigo, M; Kitagawa, H | 1 |
| Hayakawa, M; Morise, K; Ohno, R; Saito, H | 1 |
| Arima, S; Futami, K; Kinashi, M; Shigeta, M; Shimura, H | 1 |
| Fujita, H; Ikuzawa, M; Kawai, Y; Matsuki, M; Muto, S; Nakajima, S; Ogawa, K; Shimamura, M; Togawa, M; Yoshikumi, C | 2 |
| Nakamura, A; Ohkawa, T; Okamoto, Y | 1 |
| Abe, Y; Kido, Y; Kobayashi, M; Mori, T; Naruko, M; Niwa, H; Ogawa, Y; Tane, S | 1 |
| Kamiya, H; Nagai, S; Sakai, K; Sato, K | 1 |
| Aota, M; Daitoh, N; Jinno, K; Nakayama, S; Yokomise, H | 1 |
| Anai, H; Fukuchi, K; Kusumoto, H; Maehara, Y; Miyamoto, K; Sugimachi, K | 1 |
| Maeda, T | 1 |
| Burgess, M; Pasterz, R; Savaraj, N | 1 |
| Kimoto, M; Nagano, H; Sano, K | 2 |
| Ganina, KP; Zhero, SV | 1 |
| Anai, H; Kusumoto, H; Maehara, Y; Masuda, H; Sugimachi, K | 1 |
| Kimura, K; Seki, H; Takahashi, H | 1 |
| Asagoe, T; Hanaue, H; Kitano, Y; Kurosawa, T; Miyakawa, S; Nemoto, A; Shikata, J; Takada, T; Yamamoto, H; Yasuda, H | 1 |
| Asensio, F; Candel, M; Delgado, F; Garcia, J; Lledó, S; Redón, J; Roig, JV; Sanchez, A; Sanchis, C; Villar, A | 1 |
| Konishi, R; Nakamura, J; Sasaki, H; Shibasaki, J | 1 |
| Konami, T; Konishi, T; Pak, K; Takayama, H; Tomoyoshi, T | 1 |
| Amano, T; Fujimoto, Y; Imada, T; Matsumoto, A; Noguchi, Y; Tamura, S; Yamamoto, Y | 1 |
| Abe, T; Horiike, S; Inazawa, J; Misawa, S; Nishigaki, H; Okuda, T; Taniwaki, M; Tsuji, H; Yashige, H; Yokota, S | 1 |
| Fujita, H; Furue, H; Hasegawa, K; Kurihara, M; Nakao, I; Niitani, H; Tsukagoshi, S | 1 |
| Kamiwatari, M; Kosya, S; Nagata, Y; Shiokawa, H; Ueda, T; Yamada, E; Yamamoto, S | 1 |
| Kanno, M; Katakura, R; Kitahara, M; Mori, T; Niizuma, H; Suzuki, J; Wada, T; Yoshimoto, T | 1 |
| Aoki, Y; Fukunaga, H; Katsumi, M; Kawaguchi, T; Konishi, R; Oka, S; Takifuji, K; Tamaki, Y; Yukawa, H | 1 |
| De Clercq, E; Hoshi, A; Iigo, M; Nakajima, Y | 1 |
| Imai, S; Nio, Y; Ohgaki, K; Tobe, T | 1 |
| Gunge, N; Iwamoto, S; Kimoto, M; Murei, T; Nagano, H; Sano, K; Seo, Y; Yamamoto, Y | 1 |
| Fukuzumi, N; Ikeda, Y; Kaga, F; Kitajima, M; Kiuchi, T; Okada, N | 1 |
| Honda, M; Hosoya, Y; Mukae, K; Murahashi, I; Takasaki, E | 1 |
| Anai, H; Fukuchi, K; Kusumoto, H; Kusumoto, T; Maehara, Y; Miyamoto, K; Sugimachi, K | 1 |
| Adachi, S; Ishida, M; Kanazawa, K; Misawa, Y; Takeuchi, S; Yoshiya, N; Yuzawa, H | 1 |
| Ishizawa, T; Shimazu, H; Takao, S; Yamada, K | 1 |
| Fujita, Y; Nishioka, B; Otsuji, E; Takahashi, T; Yamaguchi, T; Yamane, T | 1 |
| Fujimoto, T; Ishida, T; Kurogoh, F; Ohyanagi, H; Okumura, S; Saitoh, Y; Shimada, Y; Tagashira, Y; Uchida, K; Yamamoto, M | 1 |
| Andersen, E; Pedersen, H | 1 |
| Anai, H; Kusumoto, H; Kusumoto, T; Maehara, Y; Sugimachi, K | 2 |
| Hamada, J; Hosokawa, M; Kobayashi, H; Komatsumoto, M; Li, S; Okayasu, T; Takeichi, N; Tanabe, T | 1 |
| Abe, M; Amano, T; Imada, T; Matsumoto, A; Tamura, S; Yamamoto, Y | 1 |
| Baba, T; Furukohori, N; Itoh, T; Kawata, K; Kimura, T; Munakata, A; Saitoh, S; Sakata, Y; Suzuki, H; Tamura, Y | 1 |
| Inoue, H; Kawada, S; Koide, S; Ogawa, J; Shohtsu, A | 1 |
| Arima, S; Futami, K; Sakaida, R; Shigeta, M; Shinohara, T; Tateishi, S; Yoshimura, S | 1 |
| Hattori, T; Jinushi, K; Kim, R; Kirihara, Y; Niimi, K; Niimoto, M; Nishiyama, M; Saeki, T; Takagami, S; Toge, T | 1 |
| Kikuchi, K; Kunii, Y; Mori, Y; Nitta, A; Saitou, T; Takahashi, N | 1 |
| Fukushi, G; Itoh, T; Kimura, M; Kimura, T; Kishibe, T; Saitoh, S; Sakata, Y; Suzuki, H; Tamura, Y; Tsushima, K | 1 |
| Ito, T; Nehashi, Y; Sasaki, J; Sasaki, Y | 1 |
| Peek, U | 1 |
| Hashimoto, T; Iigima, N; Iwasaki, M; Kameya, S; Narita, M; Sato, M; Sou, M; Takeshita, T | 1 |
| Eida, K; Fukuda, Y; Hirano, T; Ishii, T; Kotake, Y; Kusano, H; Nakagoe, T; Shimizu, T; Shimoyama, T; Tomita, M | 1 |
| Hatano, T; Hayakawa, M; Igarashi, M; Kashiwabara, N; Koyama, Y; Miyazato, T; Osawa, A; Saito, S; Sato, K | 1 |
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| Miki, H; Nakagawa, Y; Ogawa, N; Suzuki, H; Takahashi, M; Tominaga, M | 1 |
| Fuchimoto, S; Iwagaki, H; Miyake, M; Orita, K; Shiiki, S | 1 |
| Nakamura, K; Ozaki, H; Tajiri, H; Yoshimori, M | 1 |
| Furue, H; Goto, Y; Kimura, T; Kondo, T; Nakao, I; Orita, K; Sato, S; Taguchi, T; Takino, T; Uchino, H | 1 |
| Aogauchi, R; Ishii, N; Nakamura, K; Tsubota, N; Yamashita, C; Yoshikawa, K | 1 |
| Hayashi, K; Kitamura, M; Kosaki, G; Takahashi, I; Tominaga, T | 1 |
| Arai, Y; Endo, T; Kido, C; Ota, K; Suyama, K | 1 |
| Iizuka, N; Machida, T; Masuda, F; Mori, Y; Nakada, J; Ohnishi, T; Suzuki, M | 1 |
| Ichihashi, H; Ikenaga, T; Isomatsu, T; Kondo, T; Nakajima, T; Nakamura, T; Sakabe, T; Shiratori, T; Taguchi, T; Yamauchi, M | 1 |
| Furue, H; Hattori, T; Itoh, I; Kimura, T; Kondo, T; Ogawa, N; Taguchi, T | 1 |
| Byfield, JE; Floyd, RA; Frankel, SS; Griffiths, JC; Hornbeck, CL; Sharp, TR | 1 |
| Kataba, Y; Kikuchi, H; Maruyama, Y; Namatame, K; Otani, Y; Watanabe, H; Yamanaka, T; Yoshida, K | 1 |
| Hatta, M; Hirakawa, T; Kito, T; Kobari, T; Nakazato, H; Yamamura, Y; Yasue, M | 1 |
| Aoki, S; Hirahara, K; Hirose, S; Hori, M; Kitagawa, M; Nakagawa, H; Nishimura, K | 1 |
| Koyama, H; Nishizawa, Y; Shiba, E; Terasawa, T | 1 |
| Sakata, Y; Yoshida, Y | 1 |
| Kamiya, H; Nagai, S; Sakai, K; Sawada, T; Tsukasaki, K | 1 |
| Hasegawa, H; Takada, T; Uchiyama, K; Yasuda, H | 1 |
| Kimura, M; Koida, T | 1 |
| Arai, T; Honda, M; Kanbe, K; Kaneko, K; Maeda, S; Mukae, K; Murahashi, I; Sakuma, H; Tabata, Y; Takasaki, E | 1 |
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| Nakazato, H; Ota, K; Yamamura, Y; Yasue, M | 1 |
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| Segawa, T; Toide, K; Unemi, N | 1 |
| Byfield, JE; Frankel, SS; Griffiths, JC; Hornbeck, CL; Sharp, TR | 1 |
| Fujimoto, S; Higuchi, M; Kitsukawa, Y; Miyazaki, M; Okui, K | 1 |
| Asakawa, H; Koyama, K; Otake, S; Otawa, H | 1 |
| Kutsuna, T; Matsumoto, S; Nagai, K; Nomoto, S; Sugimoto, T; Yoshizaki, S | 1 |
| Asano, M; Kitamura, O; Kogire, M; Matsumoto, M; Noda, H; Yamada, T; Yoshida, A | 1 |
| Fujiwara, M; Futatsuki, K; Ishibashi, I; Izuno, O; Kanda, Y; Shimada, S; Suda, Y; Takayama, S; Takemori, Y; Takubo, K | 1 |
| Abe, O; Akiyama, H; Hattori, T; Inokuchi, K; Inoue, K; Kondo, T; Muto, T; Nakajima, T; Taguchi, T; Usugane, M | 1 |
| Hattori, Y; Horiuchi, M; Miyake, H; Murakami, T; Otake, H; Sawaki, S; Takahashi, H; Takeyama, I; Tamamushi, N; Yao, K | 1 |
| Hirano, H; Kawai, Y; Nishiyama, M; Sugiyama, Y; Taniguchi, H; Uematsu, A; Yanase, H | 1 |
| Ass, NIa; Borisov, VI; Mamontov, AS | 1 |
| Kobayashi, T; Mishina, T; Miyakoda, K; Nakagawa, S; Nakao, M; Toyoda, K | 1 |
| Hisazumi, H; Kanda, S; Katsumi, T; Kawaguchi, K; Mikawa, I; Misaki, T; Miyagi, T; Nakamura, T; Orito, M; Sakai, A | 1 |
| Ohwada, M; Sekiguchi, I; Suzuki, M; Tamada, T | 1 |
| Iwanaga, T; Koyama, H; Sasaki, Y; Shiba, E; Terasawa, T; Wada, A | 1 |
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| Ishijima, B; Mizutani, T; Morimatsu, Y; Sato, J; Yasue, M | 1 |
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| Furusawa, S; Monma, K; Sasaki, K; Takayanagi, G | 1 |
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| Heim, ME; Queisser, W | 1 |
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| Kimura, K; Suga, S | 1 |
| Abe, T; Fuse, Y; Nishida, K; Takino, T; Yokota, S; Yoshida, J | 1 |
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| Fujii, S; Shirasaka, T | 2 |
| Asaoka, K; Horiuchi, M; Inuyama, Y; Kohno, N; Mashino, S; Ozu, R | 1 |
| Anttila, MI; Kairaluoma, MI; Mokka, RE; Sotaniemi, EA; Sundquist, HT | 1 |
| Matsumoto, S; Nogaki, H; Tamaki, N; Taomoto, K | 1 |
| Andoh, H; Fujii, Y; Gotoh, M; Hagiwara, H; Hara, Y; Kataoka, J; Kobayashi, T; Komuro, K; Nagasaki, Y; Nagayama, A; Nakamura, K; Nakamura, R | 1 |
| Ishii, K; Kagaya, T; Koike, D; Odake, Y; Ohyama, K; Saitoh, T; Takebe, T; Takiyama, Y | 1 |
| Fukuda, K; Komatubara, S; Sato, G; Teramoto, S | 1 |
| Hattori, M; Horiike, N; Kanaoka, M; Ohta, Y; Onji, M; Yamashita, Y; Yoshida, T | 1 |
| Majima, H; Sueyoshi, K | 1 |
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| Akazawa, S; Futatsuki, K; Hattori, M; Ishibashi, I; Kanda, Y; Sendai, H; Shimada, S | 1 |
| Bedikian, AY; Bodey, GP; Karlin, D; Korinek, J; Stroehlein, J | 1 |
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| Creagan, ET; Hahn, RG; Moertel, CG; O'Connell, MJ; Rubin, J; Schutt, AJ | 1 |
| Fujii, M; Murakami, N | 1 |
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| Kamada, T; Kojima, J; Monna, J | 1 |
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| Abe, T; Fukuda, S; Fuse, Y; Kato, T; Kodama, T; Naito, E; Shimono, M; Takino, T; Tsuji, K; Yorioka, S | 1 |
| Ikeuchi, H; Kano, K; Machida, T; Miura, Y; Takahashi, M; Yoshida, K | 1 |
| Hara, Y; Kono, A; Sugata, S; Tanaka, M | 1 |
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| Abe, Y; Hiramoto, Y; Inokuchi, K; Kano, T; Kumashiro, R; Masuda, H; Notsuka, T | 1 |
| Arima, S; Futami, K; Jyozaki, H; Kinashi, M; Shigeta, M; Shimura, H | 1 |
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| Bedikian, AY; Bodey, GP; Burgess, MA; Valdivieso, M | 1 |
| Bekki, E; Hashimoto, I; Kasai, Y; Mikami, J; Nakamura, T; Nakanishi, Y; Nishi, H; Nishindai, H; Sawada, Y; Yoshimoto, M | 1 |
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| Taguchi, T; Wakui, A | 1 |
| Kawabata, N; Kitagawa, H; Kuwamura, T; Satoh, T; Sugiyama, S | 1 |
| Abe, O; Akiyama, H; Hattori, T; Inokuchi, K; Inoue, K; Ito, I; Kondo, T; Muto, T; Nakajima, T; Taguchi, T | 1 |
| Kawabata, N; Kuwamura, T; Odaka, Y; Satoh, T; Sugiyama, S | 1 |
| Izumi, T; Kurihara, M; Maruyama, T; Miyasaka, K; Sasaki, Y | 1 |
| Kako, N; Kawaguchi, T; Kimura, Y; Nomura, S; Okouchi, Y; Soejima, S; Soga, S | 1 |
| Fujii, S; Hoshino, A; Kamiya, O; Kimura, K; Kojima, T; Nagata, K; Ohara, K; Sugihara, T; Suzuki, M; Yamada, M | 1 |
| Ihara, O; Imamura, T; Johjima, Y; Kondo, Y; Murakami, T; Oohara, T; Shimazu, R | 1 |
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| Asakura, T; Hirano, H; Kawai, Y; Nishimura, K; Ri, T; Sugiyama, Y; Tamaishi, Y; Taniguchi, H; Uematsu, A | 1 |
| Haruno, A; Kunimune, Y; Morita, K; Unemi, N; Yamamoto, J; Yamashita, K; Yoshimura, Y | 1 |
| Okazaki, N; Reyes, JM; Yoshida, T; Yoshino, M | 1 |
| Fujimoto, S; Hosaka, T; Karaki, S; Kawanomoto, S; Kitsukawa, Y; Miyazaki, M; Okui, K | 1 |
| Aga, Y; Fujita, J; Sumiyoshi, Y; Uyama, T; Yamamoto, A; Yonezawa, M | 1 |
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| Kobayashi, T; Maegawa, M; Mishina, T; Nakagawa, S; Nakao, M; Watanabe, H | 1 |
| Grönross, M; Jäntti, V; Salminen, L | 1 |
| Fujimori, T; Fukui, H; Hasegawa, T; Hayashi, Y; Ishii, Y; Katayama, S; Kohno, I; Nakagiri, Y; Okazaki, H; Sakaguchi, K | 1 |
| Chin, N; Endoh, S; Fukui, H; Hasegawa, T; Hayashi, Y; Ishii, Y; Kohno, I; Nakagiri, Y; Okazaki, H; Rin, K | 1 |
| Hatsuse, K; Hiraide, H; Iwasa, H; Kadota, T; Kanabe, S; Kurokawa, T; Mimura, K; Mizoguchi, O; Tamaki, K; Terashima, H | 1 |
| Matsuura, H; Nakazawa, S | 1 |
| Fujii, S; Harada, N; Miyauchi, S; Nakamura, H; Nishioka, N; Shirasaka, T; Tanaka, H; Yu-Qin, W | 1 |
| Endo, S; Furukawa, R; Katsumi, S; Mukae, S; Sato, T; Sekine, S; Watanabe, I; Watanabe, S | 1 |
| Ajima, J; Kobayashi, N; Negishi, T; Owada, F; Saito, T; Satake, I; Tari, K; Yoshida, K | 1 |
| Hanatani, Y; Sato, H; Sato, T | 1 |
| Akazawa, S; Fujiki, T; Futatsuki, K; Honda, T; Izuno, O; Kanda, Y; Nakagawa, T; Sampi, K; Suda, Y | 1 |
| Abe, Y; Inokuchi, K; Kano, T; Kumashiro, R; Notsuka, T; Tamada, R | 1 |
| Mikhaĭlova, LM; Suslov, NI; Syrkin, AB; Voronia, TA | 1 |
| Ibayashi, J | 1 |
| Izumi, T; Kurihara, M; Maruyama, T; Sasaki, Y; Shirakabe, H | 1 |
| Akiyoshi, T; Arinaga, S; Kawaguchi, M; Koba, F; Miyazaki, S; Tsuji, H; Wada, T | 1 |
| Fujita, F; Fujita, M; Taguchi, T | 1 |
| Karakama, T; Kimura, S; Mitsushima, T; Okeda, R; Toizumi, S; Yokoyama, Y | 1 |
| Fukaya, Y; Imai, N; Kato, K; Kumazawa, H; Noguchi, A; Shioya, M | 1 |
| Honda, M; Kanbe, K; Kaneko, K; Maeda, S; Murahashi, I; Takahashi, E | 1 |
| Inokuchi, K; Kano, T; Kumashiro, R; Maehara, Y; Miyahara, M; Notsuka, T; Tamada, R | 1 |
| Arakawa, M; Inomata, T; Mizuno, H; Shimizu, F; Umezawa, T | 1 |
| Abe, O; Akiyama, H; Hattori, T; Inokuchi, K; Inoue, K; Kikuchi, K; Kondo, T; Muto, T; Nakajima, T; Taguchi, T | 1 |
| Byfield, JE; Hornbeck, CL; Tang, SG | 1 |
| Aoki, N; Hamada, S; Hirayama, R; Matsumura, J; Mishima, Y; Miyanaga, T; Takagi, Y | 1 |
| Furue, H; Furusawa, M; Hattori, T; Inokuchi, K; Ito, I; Niimoto, M; Ogawa, N; Orita, K; Tamada, R; Toda, T | 1 |
| Ando, Y; Ichijo, M; Kamamoto, Y; Moriyama, I; Nakanishi, A; Noda, T; Saitoh, S; Tsuji, Y; Yoh, S | 1 |
| Furue, H | 2 |
| Fujita, H; Kosaka, T; Miyazaki, I; Takashima, S; Ueno, K | 1 |
| Hatae, M; Hokanishi, H; Terahara, M | 1 |
| Müller, U; Tanneberger, S | 1 |
| Hirose, S; Iwamoto, M; Yoshida, S | 1 |
| Kawata, S; Marunaka, T; Minami, Y; Okamoto, M; Tarui, S; Yamano, T | 1 |
| Fukuda, M; Furuhata, A; Nakahashi, M; Ohshima, H; Satomi, Y; Senga, Y | 1 |
| Itoh, S; Kameda, C; Katsu, K; Saka, M; Shiomi, M; Tanaka, T | 1 |
| Kajitani, T; Kuno, K; Nakajima, T; Takagi, K; Takahashi, T | 1 |
| Hamaya, K; Hirose, S; Kataoka, K; Kimura, H; Kitamura, M; Mano, K; Ohara, T; Tsutsui, N | 1 |
| Asagoe, T; Hanaue, H; Horie, F; Kitano, Y; Kurosawa, T; Miura, S; Miyagawa, S; Nemoto, A; Shikata, J | 1 |
| Hsu, SC; Sun, CC | 1 |
| Fukuoka, K; Ishitsuka, H; Itoga, A; Maruyama, HB; Miwa, M; Takemoto, K | 1 |
| Ishitsuka, H; Kitta, K; Ohta, Y; Sueki, K; Takemoto, K; Yagi, Y | 1 |
| Fukazawa, H; Hongu, Y; Ichihara, S; Shimizu, H; Suzuki, S | 1 |
| Miyauchi, S; Unemi, N; Yamada, Y | 1 |
| Benvenuto, J; Drewinko, B; Freireich, EJ; Ho, DH; Loo, TL; Yang, LY | 1 |
| Grigorova, TM; Marenich, AF; Vartanian, LG | 1 |
| Gotohda, E; Hosokawa, M; Kawamura, T; Kobayashi, H; Kodama, T; Yamada, Y | 1 |
| Levenson, CH; Meyer, RB | 1 |
| Fujimoto, S; Gambe, K; Hikosaka, T; Hosaka, T; Itoh, K; Karaki, S; Kawanomoto, S; Tazawa, T | 1 |
| Fujii, S; Fukushima, M; Ikenaka, K; Kitano, S; Maehara, Y; Nakamura, H; Shirasaka, T | 1 |
| Fujii, S; Kawaguchi, Y; Marunaka, T; Morita, K; Nakamura, Y; Sato, T; Takeda, S; Unemi, N | 1 |
| Marunaka, T; Minami, Y; Umeno, Y | 1 |
| Berzinia, VIu; Britsis, FA; Krampe, RA; Purkalne, TS; Zakenfel'd, GK | 1 |
| Omuraliev, A | 1 |
| Namba, M; Ueki, H | 1 |
| Fujii, S; Marunaka, T; Minami, Y; Sato, T; Umeno, Y; Yasuda, A | 1 |
| Isobe, K; Kimura, K; Kitamura, M; Kubo, K; Shimaji, T; Suga, S; Suzuoki, Y | 1 |
| Mattern, J; Volm, M; Wayss, K; Weber, N | 1 |
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| Narisawa, T; Sato, M; Takahashi, T; Tani, M | 1 |
| Chudina, AP; Sel'chuk, VIu | 1 |
| Fujii, S; Marunaka, T; Minami, Y; Nagamachi, M; Umeno, Y; Yoshida, K | 1 |
| Akiyama, J; Gotohda, E; Hosokawa, M; Kawamura, T; Kobayashi, H; Kodama, T; Yamada, Y | 1 |
| Friedman, MA; Ignoffo, RJ | 1 |
| Marunaka, T; Umeno, Y | 1 |
| Sakurai, Y | 1 |
| Jellinghaus, W; Maurer, W; Müller, V; Schultze, B; Weis, G | 1 |
| Goetz, P; Novotná, B | 1 |
| Arnold, W; Fichtner, I; Naundorf, H | 1 |
| Fukuda, I; Iwanaga, T; Koyama, H; Nishizawa, Y; Takahashi, Y; Terasawa, T; Wada, T | 1 |
| Esaki, K; Horikoshi, N; Inagaki, J; Inoue, K; Kobayashi, T; Murosaki, S; Nagura, E; Ogawa, M; Okabe, K; Takano, Y; Ueoka, H | 1 |
| Kimura, K | 1 |
| Kawaguchi, Y; Masuda, H; Nagayama, S; Yasuda, A | 1 |
| Fujimoto, S; Kitsukawa, Y; Miyazaki, M; Okui, K | 1 |
| Arakawa, M; Inomata, T; Sasagawa, K; Shimizu, F; Shinkai, K | 1 |
| Adámek, R; Blasko, M; Brezina, V; Chrz, R; Goetz, P; Michalová, K; Musilová, J; Novotná, B; Pogosianz, HE; Raposa, T; Siracký, J; Sokova, OI; Thust, R; Ujházy, V; Volgareva, GM; Vrba, M | 1 |
| Haruno, A; Toide, K; Unemi, N; Yamamoto, J; Yoshimura, Y | 1 |
| Hara, Y; Kono, A; Matsushima, Y | 1 |
| Byfield, JE; Floyd, RA; Griffiths, JC; Hornbeck, CL | 1 |
| Mechl, Z | 1 |
| Klein, HO; Löffler, T; Mohr, R; Oerkermann, H; Voigtmann, R; Wickramanayake, PD | 1 |
| Arnold, H; Drings, P; Fritze, D; Geldmacher, J; Hartwich, G; Herrmann, R; Kempf, P; König, H; Meiser, RJ; Nedden, R; Pappas, A; Queisser, W; Schaefer, J; Schnitzler, G; Sievers, H; von Oldershausen, HF; Wahrendorf, J; Westerhausen, M; Witte, S | 1 |
| Belitsky, GA; Bukhman, VM; Konopleva, IA | 1 |
| Maezawa, S; Matsuoka, S; Ohira, S; Saito, T; Sakuma, M; Wakui, A | 1 |
| Aoki, Y; Furukawa, H; Iwanaga, T; Kabuto, T; Taniguchi, K; Terasawa, T | 1 |
| Blokhina, NG; Sorokina, GA | 1 |
| Jimi, S; Kato, Y; Kawakami, M; Matsuyama, T; Morita, T; Nishimura, A; Shigyo, R; Sugimori, H; Taki, I; Tanaka, M; Toyota, Y; Tsukamoto, N; Watanabe, E; Yamashita, H | 1 |
| Mori, T; Sakahira, H; Sato, S; Suzuki, M; Wakisaka, T; Yajima, A; Yamauchi, R | 1 |
| Kanbara, H; Kawashima, Y; Kitade, F; Kurokawa, A; Okada, K; Okajima, K; Sakuramoto, K; Yamada, S | 1 |
| Frendewey, DA; Kaiser, II; Kladianos, DM; Moore, VG | 1 |
| Pogosiants, EE; Stavrovskaia, AA; Volgareva, GM | 1 |
| Grossie, VB; Loo, TL; Rosenblum, MG | 1 |
| Gürtler, R; Lenk, H; Matthes, ML; Tanneberger, S | 1 |
| Amberger, H; Bachmann, U; Habs, M; Schmähl, D; Wagner, I | 1 |
| Tschiersch, B | 1 |
| Koyama, H; Terasawa, T; Wada, T | 1 |
| Fujiwara, T; Kobayashi, T; Maegawa, M; Mishina, T; Nakagawa, S; Nakao, M; Watanabe, H | 1 |
| Byfield, JE; Calabro-Jones, P; Klisak, I; Kulhanian, F | 1 |
| Hamada, S | 1 |
| Furusawa, S; Sasaki, K; Takayanagi, G | 1 |
| Iwanaga, T; Koyama, H; Nishizawa, Y; Terasawa, T; Wada, T | 1 |
| Komi, N; Korematsu, H; Kunitomo, K; Kuwashima, T; Tamura, T; Toyosaki, M; Yoshikawa, H | 1 |
| Ejiri, T; Kakizaki, K; Matsuno, S; Sato, T | 1 |
| Hirota, T; Okazaki, N; Tajiri, H; Yamaguchi, H; Yoshida, S; Yoshimori, M | 1 |
| Abe, O; Fujimoto, S; Furue, H; Furusawa, M; Hashimoto, I; Hattori, T; Inokuchi, K; Itoh, I; Koga, S; Kondo, T; Niimoto, M; Ogawa, N; Ohya, M; Orita, K; Sugiyama, Y; Tamada, R; Toda, T | 1 |
| Amano, R; Ando, H; Fujii, Y; Hara, Y; Hashiguchi, F; Komuro, K; Kurata, T; Nakamura, K; Nakamura, R; Sakamoto, R; Shimada, A; Yamazaki, M | 1 |
| Asakawa, H; Matsumoto, K; Otawa, H; Yamada, S | 1 |
| Babaya, K; Hiramatsu, T; Hirao, Y; Ijuin, M; Kihoin, K; Maruyama, Y; Ohara, S; Okajima, E; Tanaka, M | 1 |
| Fukuzumi, N; Ikeda, Y; Kaga, F; Kitajima, M; Seki, M; Sohma, S; Yagita, A | 1 |
| Inuo, T; Kaneko, H; Ohashi, A; Sekizawa, Y; Tsuchiya, S | 1 |
| Asahi, T; Kaneshige, T; Kumon, H; Matsumura, Y; Ohmori, H; Ozaki, Y; Tsushima, T; Yoshimoto, J | 1 |
| Higashi, Y; Nomoto, C; Suemasu, K | 1 |
| Goto, Y; Kikuchi, T; Nakazawa, I; Nomura, N; Ouchi, E; Suzuki, N | 1 |
| Fukuda, O; Inoue, S; Maeyama, M; Nakayama, M; Tajima, C; Tokunaga, T | 1 |
| Fukao, K; Ishikawa, A; Iwasaki, Y; Nagoshi, K; Okamura, T; Orii, K; Ozaki, A; Sarashina, H; Takase, Y; Takeshima, T; Todoroki, T | 1 |
| Sakamoto, A; Tomioka, M; Usami, M | 1 |
| Jimi, S; Kato, Y; Kawakami, M; Kidera, Y; Matsuyama, T; Morita, T; Nishimura, A; Shigyo, R; Sugimori, H; Tanaka, M; Toyota, Y; Tsukamoto, N; Watanabe, E; Yamashita, H | 1 |
| Abe, O; Akiyama, H; Hattori, T; Hayasaka, A; Inokuchi, K; Inoue, K; Ito, I; Kasai, Y; Kikuchi, K; Kondo, T; Muto, T; Nakajima, T; Sugie, S; Taguchi, T | 1 |
| Kikuchi, K; Majima, S; Murakami, M | 1 |
| Okuda, M; Sato, K; Teramoto, T; Uematsu, Y; Ushijima, Y; Yoshida, H | 1 |
| Yamada, E | 1 |
| Okabe, H; Takeda, S; Toko, T; Unemi, N; Yuasa, C | 1 |
| Demachi, H; Konishi, K; Kuroda, Y; Tsugawa, K; Tsuji, M; Yabushita, K | 1 |
| Kuroda, T; Moriyama, A; Murata, I; Ogami, Y; Otsuki, M; Tabaru, A; Yoshikawa, I | 1 |
| Hirata, K | 1 |
| Itokazu, T; Kochi, A; Koja, S; Maeda, H; Maeshiro, N; Matsumura, J; Noda, Y; Yasuda, S | 1 |
| Furukawa, H; Goto, S; Hiratsuka, M; Iwanaga, T; Kito, T; Nakajima, T; Nakazato, H; Ohta, K; Okabayashi, K; Yamamura, Y | 1 |
| Suda, Y; Uchida, K | 1 |
| Fort, FL; Kikuchi, Y; Nakamura, M | 1 |
| Akiyama, S; Furukawa, T; Haraguchi, M; Sumizawa, T | 1 |
| Hiroshige, K; Ikeda, T; Korenaga, D; Nishizaki, T; Sugimachi, K; Takenaka, K; Yoshida, K | 1 |
| Hirota, Y; Hongo, J; Iijima, Y; Inagaki, M; Koyama, M; Ozaki, M; Wada, K | 1 |
| Harada, S; Matsuo, M; Miyata, M; Obara, T; Oikawa, H; Ping, L; Takahashi, T; Yanagisawa, T | 1 |
| Ikeda, K; Shibata, N; Tamai, M | 1 |
| Arima, H; Arita, S; Hachisu, T; Hisikawa, E; Kashiwabara, H; Matsumoto, M; Sakamoto, K; Yaguchi, H; Yokoyama, T | 1 |
| Aida, I; Kasuga, Y; Ohwada, M; Sato, I; Suzuki, M; Tamura, T | 1 |
| Horiuchi, Y; Ina, K; Iwase, H; Kaneko, H; Kuroiwa, A; Kusugami, K; Morise, K; Oka, Y; Shinoda, M; Suga, S | 1 |
| Ban, K; Higashi, H; Ishihara, S; Kitazaki, M; Machida, T; Masuda, K; Matsumoto, M; Noma, M; Ota, M; Shida, H | 1 |
| Higaki, T; Ito, Y; Kono, S; Moriguchi, M; Nakata, Y; Oishi, H; Seki, N; Takahashi, T; Takano, S; Watanabe, Y | 1 |
| Wakui, A | 1 |
| Kitada, K; Mochida, A; Nakamura, H; Omori, S | 1 |
| Katai, H; Maruyama, K; Okajima, K; Sano, T; Sasako, M | 1 |
| Demachi, H; Hayakawa, Y; Hirose, S; Maruhashi, Y; Miwa, A; Nakagawa, H; Nakanuma, Y; Ohta, H; Satomura, Y | 1 |
| Kanetake, H; Minami, Y; Saito, Y; Sakai, H | 1 |
| Esu, H; Itokazu, T; Kamiya, S; Kanazawa, T; Koja, S; Maeshiro, N; Noda, Y; Simoji, Y; Yamauchi, M | 1 |
| Kanazawa, Y; Kurogi, S; Masuda, K; Noda, Y; Shinohara, S | 1 |
| Endo, T; Hatakeyama, S; Ho, N; Katagiri, J; Onuki, K; Sasagawa, T; Sekine, T; Sugiyama, K; Togashi, M; Tomidokoro, T | 1 |
| Aoki, T; Ashikaga, K; Hirai, K; Kawahara, H; Kimura, C; Kuroda, H; Ono, M; Sato, K; Yamada, Y | 1 |
| Hidaki, T; Kato, T; Sugimori, H; Tazaki, T; Tsukamoto, N; Yakushiji, M; Yamabe, T | 1 |
| Hayashi, K; Imaoka, T; Kawaguchi, T; Kubo, M; Matsui, Y; Miyauchi, S; Utsunomiya, T | 1 |
| Hashimoto, T; Hirano, K; Kanehira, E; Kawakami, K; Omura, K; Shirasaka, T; Watanabe, S; Watanabe, T; Watanabe, Y | 1 |
| Fuji, N; Ito, T; Kobayashi, M; Miyauchi, T; Yamada, A | 1 |
| Baba, H; Inutsuka, S; Kohnoe, S; Maehara, Y; Oshiro, T; Sugimachi, K; Takahashi, I; Takeuchi, H | 1 |
| Homma, A; Iizuka, K; Nakamaru, Y; Yonekawa, H | 1 |
| Fukagawa, H; Hirohashi, Y; Iwanaga, A; Iyama, A; Kitahara, K; Miyazaki, K; Mori, M; Sasatomi, E; Tsutsumi, N; Yakushiji, H | 1 |
| Hanai, J; Honjoh, M; Ishikawa, Y; Ohnishi, N; Sakaguchi, H; Takeyama, M | 1 |
| Kato, K; Kawai, Y; Koide, T; Koike, A; Kojima, T; Kuroda, H; Takeshige, K; Tanaka, K | 1 |
| Kimura, K; Ko, Y; Kumada, K; Makuuchi, M; Midorikawa, T; Nakano, H; Namatame, K; Sasaki, E; Shimada, K; Takahashi, H | 1 |
| Kusumoto, S; Nadai, T; Oku, N; Shimidzu, K; Suda, Y; Sumi, M; Yamashita, S | 1 |
| Kasahara, N; Kudo, H; Mizuno, M; Mori, T; Nagasawa, H; Sakamoto, S; Sugiura, Y; Suzuki, S | 1 |
| Kumagai, K; Masuo, K; Nishida, Y; Yasui, A; Yoshitoshi, A | 1 |
| Hashimoto, T; Ishida, F; Omura, K; Watanabe, Y | 1 |
| Baba, S; Itaya, S; Kobayashi, T; Matsuda, T; Motai, H; Shimada, J; Suzuki, K; Tsuge, I | 1 |
| Hirata, K; Sasaki, K; Shirasaka, T; Yamamitsu, S | 1 |
| Kosaki, G; Kurihara, M; Tominaga, T; Yoshida, Y | 1 |
| Furusawa, M; Kakeji, Y; Matsukuma, A; Matsuoka, H; Morita, M; Ohno, S; Seo, Y; Tomoda, H | 1 |
| Itsubo, M | 1 |
| Hishinuma, S; Ikeda, T; Inada, T; Kotake, K; Koyama, Y; Kubota, T; Ogata, Y; Ozawa, I; Shimizu, H | 1 |
| Higashigawa, M; Inagaki, S; Kagawa, Y; Kakito, H; Ohkubo, T; Ooi, K; Sakurai, M; Sumida, K | 1 |
| Ishikawa, H; Kusano, H; Miyashita, K; Nakazaki, T; Ogawa, T; Shimizu, T; Shimoyama, T; Yasutake, T; Yoshida, A; Yoshida, K | 1 |
| Azuma, S; Furuta, T; Kato, M; Kuno, T; Nishina, T; Saji, S; Takahashi, K; Tanemura, H | 1 |
| Fujita, F; Fujita, M; Inaba, H; Taguchi, T | 1 |
| Harada, M; Kimura, A; Koga, K; Miura, I; Nishitani, H | 1 |
| Kawamoto, T; Koike, N; Kondou, T; Mun, Y; Nithou, M; Nozue, M; Orii, K; Sindou, T; Todoroki, T; Toko, K | 1 |
| Sakakibara, N; Watanabe, H | 1 |
| Iida, A; Ikeda, N; Komatsu, T; Ookubo, K | 1 |
| De Caro, V; Di Stefano, V; Giannola, LI | 1 |
| Baccanari, DP; Cao, S; Davis, ST; Joyner, SS; Rustum, YM; Spector, T | 1 |
| Asano, K; Imai, R; Somekawa, Y; Taira, A | 1 |
| Honma, A; Ishikawa, N; Ishikawa, T; Kamimura, T; Oota, H; Ozaki, T; Takeda, K; Yoshida, T | 1 |
| Fujioka, A; Fukushima, M; Nakano, K; Okabe, H; Oyama, K; Saito, H; Satake, H; Shirasaka, T; Takechi, T; Takeda, S; Uchida, J; Unemi, N | 1 |
| Belón, J; Blanco, E; Espinosa, E; Feliu, J; García-Alfonso, P; García-Girón, C; Garrido, P; Gómez-Navarro, J; González Barón, M; Ordónez, A; Zamora, P | 1 |
| Inutsuka, K; Maruiwa, M; Noutomi, M; Ohta, J; Tokuhara, K | 1 |
| Dohi, K; Goto, T; Haruta, R; Kataoka, T | 1 |
| Fujii, M; Kajitani, T; Miwa, K; Nakajima, T; Ohmori, Y; Sakabe, T | 1 |
| Drengler, R; Eckardt, J; Eckhardt, G; Villalona-Calero, M; Von Hoff, D | 1 |
| Akiba, T; Okeda, R; Tajima, T | 1 |
| Araki, H; Hiramatsu, Y; Kamiyama, Y; Kojima, Y; Nakagawa, A; Nakagawa, M; Ogura, T; Shirasaka, T | 1 |
| Handa, H; Honjo, K; Kawanishi, J; Nakamura, T; Nakayama, N; Ohi, M; Tsuji, Y; Uehara, S; Watanabe, Y; Yoshihito, H | 1 |
| Fujii, M | 3 |
| Chaitchik, S; Inbar, MJ; Lotan, A; Ron, IG | 1 |
| Boudinot, FD; Jarugula, VR | 1 |
| Miura, K; Murayama, H; Sakamoto, J | 1 |
| Fujii, M; Imanishi, Y; Kanke, M; Ohno, Y; Tokumaru, Y | 1 |
| Kobayashi, K | 1 |
| De Guzman, LM; Fernando, GY; Guancia, AA; Romana, IB; Samson, MC; Villalon, AH | 1 |
| Rustum, YM | 2 |
| Asano, M; Mori, T; Takahashi, K; Yasuno, M | 1 |
| Kouchi, Y; Maeda, Y; Morinaga, H; Ohuchida, A | 1 |
| Kitamura, R; Matsushima, E; Yoshida, K | 1 |
| Kiyozumi, Y; Kurano, R; Nosaka, S; Sagara, K; Takamura, K; Takeshita, S | 1 |
| Iwama, T; Kawachi, Y; Kudo, H; Murakami, S; Okayasu, I; Sagara, T; Sakamoto, S; Tsukada, K | 1 |
| Fujita, Y; Honda, I; Watanabe, S | 1 |
| Inaji, H; Koyama, H; Motomura, K; Noguchi, S | 1 |
| Hata, K; Kaganoi, J; Nanbu, H; Nishitai, R; Ohsumi, K; Tokunaga, Y | 1 |
| Baba, H; Kakeji, Y; Maehara, Y; Ohno, S; Sugimachi, K | 1 |
| Pazdur, R | 1 |
| Jones, J; Mamounas, EP; Wickerham, DL; Wieand, HS; Wolmark, N | 1 |
| Skillings, JR | 1 |
| Carmichael, J | 1 |
| Diaz-Canton, E; Pazdur, R | 1 |
| Minsky, BD | 1 |
| Codes, M; Dugue, A; Garcia, E; Iglesias, L; Moreno, JA; Murillo, E; Torrija, E; Virizuela, JA | 1 |
| Diaz-Rubio, E; Garcia Carbonero, I; González-Larriba, JL; Perez Segura, P; Sastre Valera, J | 1 |
| Arikian, S; de Andrade, CA; Delfino, C; Doyle, J; Murad, A; Sinha, N | 1 |
| Katoh, K; Koyanagi, Y; Satoh, S | 1 |
| Akazawa, S; Ariyoshi, Y; Fujita, H; Furue, H; Hara, Y; Hasegawa, K; Inuyama, Y; Kanamaru, R; Kimura, K; Kurihara, M; Nakao, I; Niitani, H; Ota, K; Saito, T; Shimoyama, T; Suga, S; Sugimachi, K; Taguchi, T; Takai, S; Takashima, S; Toge, T; Tsukagoshi, S | 1 |
| Watanabe, T | 2 |
| Fukushima, M; Kato, T; Shimamoto, Y; Shirasaka, T | 1 |
| Inamura, Y; Kanemitsu, T; Kojima, T; Miyashita, A; Naruse, T; Owa, Y; Suzumura, K | 1 |
| Zhuk, R | 1 |
| Ando, E; Fukuda, H; Fukumori, K; Kato, O; Kusaba, T; Sata, M; Tanaka, M; Tanikawa, K; Yamamoto, H; Yamashita, F; Yano, Y | 1 |
| McCann, J | 1 |
| Punt, CJ | 1 |
| Kotera, H; Kusunoki, M; Noda, M; Yamamura, T; Yanagi, H | 1 |
| Fujioka, A; Fukushima, M; Kato, T; Nakano, K; Ohshimo, H; Okabe, H; Satake, H; Shimamoto, Y; Shirasaka, T; Takechi, T; Takeda, S; Uchida, J | 1 |
| Brown, N; Covington, W; Ho, DH; Huo, YY; Kuritani, J; Lassere, Y; Pazdur, R | 1 |
| Chimori, Y; Ikoma, H; Miyamoto, Y; Nanri, M; Nishioka, B; Oguro, A; Yamane, E | 1 |
| Ishikawa, K; Kanazawa, T; Kitamura, K; Miyata, M; Nishino, H; Tanaka, H | 1 |
| Abe, O; Demura, H; Endo, M; Kawamura, E; Kimura, K; Kubota, T; Nakao, I; Saito, T; Sasano, H; Sasano, N | 1 |
| Cao, S; Frank, C; Rustum, YM; Shirasaka, T | 1 |
| Chan, KK; Groshen, S; Jeffers, S; Leichman, CG; Leichman, L; Muggia, FM; Spicer, D; Wu, X | 1 |
| Brockstein, BE; Haraf, DJ; Humerickhouse, R; Vokes, EE | 1 |
| Bunnell, CA; Winer, EP | 1 |
| Ajani, JA | 1 |
| Brito, R; Hoff, PM; Medgyesy, D; Pazdur, R; Royce, M | 2 |
| Fukushima, M; Kato, T; Ohshimo, H; Shimamoto, Y; Shirasaka, T; Uchida, J; Yonekura, R | 1 |
| Brodowicz, T; Fiebiger, WC; Hejna, MH; Kornek, GV; Miholic, J; Raderer, M; Scheithauer, W; Valencak, JB; Weinlaender, G | 1 |
| Meropol, NJ | 1 |
| Cao, S; Lu, K; Rustum, YM; Shirasaka, T; Slocum, HK; Tóth, K | 1 |
| Ichikawa, A; Inada, T; Kawakubo, H; Ogata, Y | 1 |
| Kawabata, Y; Nio, Y; Ohishi, T; Sumi, S; Tamura, K; Yano, S | 1 |
| Aiba, K; Araki, H; Mikami, Y; Shirasaka, T; Suzuki, M; Terashima, M | 1 |
| González Barón, M | 1 |
| Hoshino, K; Ikeda, H; Koyama, T; Morishita, Y; Nakamura, M | 1 |
| Doki, Y; Inoue, M; Monden, M; Shiozaki, H; Tsujinaka, T; Yamamoto, M; Yano, M | 1 |
| Adachi, Y; Fukuda, M; Fukuma, E; Nakayama, Y; Nishikawa, T; Ogata, H; Ota, T; Shimizu, K; Yamaguchi, S | 1 |
| Brito, RA; Hoff, PM; Medgyesy, D; Pazdur, R; Ravandi-Kashani, F; Royce, ME; Zukowski, TH | 1 |
| Goto, M; Iwanaga, T; Kitamura, M; Kito, T; Nakajima, T; Nashimoto, A; Okabayashi, K | 1 |
| Diasio, RB | 3 |
| Ollendorf, D | 1 |
| Colangelo, L; Mamounas, EP; Smith, R; Wickerham, DL; Wieand, HS | 1 |
| Aoki, E | 1 |
| Basaki, Y; Chikahisa, L; Hashimoto, A; Miyadera, K; Okabe, S; Wierzba, K; Yamada, Y; Yonekura, K | 1 |
| Fujii, M; Imai, S; Mochizuki, F | 1 |
| Lamont, EB; Schilsky, RL | 1 |
| Adjei, AA | 1 |
| Macdonald, JS | 1 |
| Horikoshi, N; Maehara, Y; Mitachi, Y; Sakata, Y; Shimada, Y; Sugimachi, K; Taguchi, T | 1 |
| Blanke, CD; Choy, H; Teng, M | 1 |
| Fujinami, K; Kubota, Y | 1 |
| Fujioka, M; Idezuki, Y; Inokuma, S; Ishida, H; Kamano, T; Kishi, T; Kondo, K; Matsumoto, Y; Miura, T; Murata, N; Nakada, H; Odaka, A; Shimomura, K; Suzuki, T; Takeuchi, I; Yamada, H | 1 |
| Chollet, P; de Vries, MJ; Ganser, A; Hanauske, A; Rambusch, E; Schöffski, P; Wiese, KH | 1 |
| Cao, S; Rustum, YM | 1 |
| Bekradda, M; Cvitkovic, E | 1 |
| Hasegawa, K; Kurihara, M; Matsukawa, M; Muto, Y; Sakonji, M; Takebuchi, K; Watanabe, M | 1 |
| Fujiwara, Y; Itoh, R; Kusunoki, M; Nakagawa, K; Nakao, K; Yamamura, T | 1 |
| Izumi, S; Nakagawa, J; Nishihara, M; Onoda, Y; Shimizu, N; Shiota, K; Suzuka, I | 1 |
| Aiba, K; Horikoshi, N; Ito, Y; Mizunuma, N; Ohsawa, H; Sugiyama, K; Takahashi, S | 1 |
| Kawaida, M; Kitahara, S; Kohno, N; Ohmuma, T | 1 |
| Adenis, A; Conroy, T; Paillot, B | 1 |
| Musha, N; Oka, K; Saito, H; Sando, N; Sasaki, M; Setu, M; Setu, Y; Sunami, E | 1 |
| Ajisaka, H; Bando, E; Fujimura, T; Fushida, S; Hayashi, T; Minatoya, T; Miwa, K; Nishimura, G; Taniguchi, K; Yonemura, Y | 1 |
| Fujitomi, Y; Fujiyoshi, K; Yasue, K | 1 |
| Hoff, PM; Lassere, Y; Pazdur, R | 1 |
| Fujita, M; Furukawa, H; Hirata, K; Kaibara, N; Kakegawa, T; Kasai, Y; Kitamura, M; Kubota, T; Kunii, Y; Nagawa, H; Nose, Y; Takahashi, Y; Takao, T; Takashima, S; Toge, T; Tomita, M; Wakasugi, J | 1 |
| Hasegawa, K; Koizumi, W; Kurihara, M; Nakano, S | 1 |
| Ayabe, H; Eida, K; Furukawa, M; Ino, M; Ishikawa, H; Kunisaki, T; Nakagoe, T; Nakamura, Y; Nogawa, T; Sawai, T; Tobinaga, K; Tsuji, T | 1 |
| Nashimoto, A; Tanaka, O; Yabusaki, H | 1 |
| Damjanov, N; Meropol, NJ | 1 |
| Shirasaka, T | 2 |
| Ajani, JA; Yao, JC | 1 |
| Hirata, K; Shirasaka, T; Terashima, M; Tsuji, A; Yamamitsu, S | 1 |
| Hirakawa, Y; Kawaguchi, Y; Kuwata, K; Matsushima, E; Nagayama, S | 1 |
| Hironaga, K; Kawaguchi, Y; Nagayama, S; Yamaguchi, S; Yamamoto, A; Yoshisue, K | 1 |
| Ando, J; Fujisaki, M; Ikeda, T; Imoto, S; Kobayashi, H; Kojima, M; Oka, S; Tamura, H; Wada, N | 1 |
| Ikeda, Y; Mizuno, H; Nishimura, G; Satake, K; Taguchi, T; Tsukuda, M; Yanoma, S | 1 |
| Ikeda, K; Kawaguchi, Y; Masuda, H; Matsushima, E; Nagayama, S; Yoshisue, K | 1 |
| Kusunoki, M; Noda, M; Yamamura, T; Yanagi, H; Yoshikawa, R | 2 |
| Ahmed, F; Bissett, D; Cassidy, J; McLeod, H | 1 |
| Fukuda, J; Hayatsu, M; Hoshina, H; Iida, A; Kaji, M; Miyamoto, T; Miyaura, Y; Nagashima, K; Ono, K; Takagi, R; Tsurumaki, H | 1 |
| Baba, H; Kikunaga, H; Matsudo, A; Miura, H; Morisue, A; Nakai, H; Osakabe, Y; Sotome, K; Takao, M | 1 |
| Asahara, T; Nakahara, H; Nakahara, M; Okajima, M; Yano, M | 1 |
| Kitaoka, A; Ohsumi, K; Tokuka, A; Tokunaga, Y; Yagi, T | 1 |
| Hoff, PM; Pazdur, R; Royce, ME | 2 |
| Aschele, C; Grossi, F; Guglielmi, A; Puglisi, F; Sobrero, A | 1 |
| Peeters, M; Van Cutsem, E | 1 |
| Araki, H; Fukushima, M; Kamiyama, Y; Shirasaka, T | 1 |
| Shirasaka, T; Taguchi, T; Tsuji, A; Yamamitsu, S | 1 |
| Hamazaki, K; Inagaki, M; Kawashima, T; Morichika, T; Sadamori, H; Shima, Y; Tanaka, N; Uetsuka, H; Yagi, T | 1 |
| Hirose, F; Ikeda, Y; Nakamura, Y; Nishimura, G; Satake, K; Taguchi, T; Tsukuda, M; Yanoma, S | 1 |
| Komatsu, T; Nakajima, M; Shimada, N; Yamazaki, H; Yokoi, T | 1 |
| Köhne, CH; Peters, GJ | 1 |
| Colangelo, L; Lembersky, BC; Mamounas, EP; Smith, RE; Wieand, HS | 1 |
| Ishizu, K; Makuuchi, H; Sadahiro, S; Suzuki, T; Tajima, T; Tokunaga, N | 1 |
| Katai, H; Saka, M; Sano, T; Sasako, M | 1 |
| Ohtsu, A; Tahara, M | 1 |
| Chiba, K; Ikeda, K; Kawaguchi, Y; Kobayashi, K; Matsushima, E; Nagayama, S; Tyson, CA; Yoshisue, K | 1 |
| Lewis, NL; Meropol, NJ | 1 |
| Harboe, K; Lind, A; Ogreid, D; Todnem, K; Zotova, L | 1 |
| Wada, H | 1 |
| Maeda, Y; Sasaki, T | 1 |
| Kodaira, S; Nozawa, K; Shatari, T | 1 |
| Hayabuchi, N; Ikeda, S; Iwamoto, M; Nagata, S; Niiya, F; Odou, E | 1 |
| Fukunaga, M; Goda, F; Maeba, T; Maeta, H; Mihara, T; Mori, S; Ohkawa, M; Okada, H; Okano, K; Senda, S; Uchida, Y; Usuki, H; Wakabayashi, H | 1 |
| Dwivedy, S; Hoff, PM; Medgyesy, D; Pazdur, R; Royce, ME; Zukowski, TH | 1 |
| Hoff, PM; Saad, ED | 1 |
| Furuyama, JI; Hashimoto-Tamaoki, T; Kusunoki, M; Noda, M; Yamamura, T; Yanagi, H; Yoshikawa, R | 1 |
| Aoyagi, S; Hisamatsu, T; Ikezawa, T; Matsuoka, K; Mizuno, Y; Motohashi, Y; Nishida, J; Tatsuno, S | 1 |
| Ikeda, S; Iwamoto, M; Nagata, S; Niiya, F; Shirouzu, K | 1 |
| Colangelo, L; Wieand, S; Wolmark, N | 1 |
| de Bono, JS; Twelves, CJ | 1 |
| Alberts, D; Brooks, D; Damle, B; Ferreira, I; Kaul, S; Pazdur, R; Ravandi, F; Sonnichsen, D; Stewart, D | 1 |
| Kawaguchi, Y; Komatsu, T; Nagayama, S; Nakajima, M; Shimada, N; Yamazaki, H; Yokoi, T | 1 |
| Cunningham, D; James, RD | 1 |
| Kubota, T | 1 |
| Komatsu, T; Nakajima, M; Shimada, N; Takemoto, K; Yamazaki, H; Yokoi, T | 1 |
| Brátová, M; Kohout, P; Králícková, P; Melichar, B; Solichová, D; Zadák, Z | 1 |
| Kawaguchi, Y; Nagayama, S; Shindo, T; Yoshisue, K | 1 |
| Kaniwa, N; Murayama, N; Nakajima, Y; Ohno, Y; Ozawa, S; Sai, K; Sawada , J | 1 |
| Akagi, Y; Kobayashi, H; Matono, K; Miyagi, Y; Nakagawa, M; Nozoe, Y; Ogata, Y; Sasatomi, T; Shirouzu, K | 1 |
| White, RM | 1 |
| Iwase, H; Kameya, T; Makuuchi, H; Sadahiro, S; Suzuki, T; Tajima, T | 1 |
| Kohno, H; Nagasue, N; Nazmy El Assal, O; Ono, T; Yamanoi, A | 1 |
| Coleman, R; Cunningham, D | 1 |
| Kostromina, KN; Parkhomenko, IM; Pavlov, AS; Simakina, EP | 1 |
| Jones, R; Twelves, C | 1 |
| Borner, M; Maroun, J; Scheithauer, W; Twelves, C; Wilke, H | 1 |
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| Goto, M; Hamaguchi, T; Matsumura, Y; Muro, K; Shirao, K; Tsukioka, Y; Yamada, Y | 1 |
| Akamo, Y; Hasegawa, M; Manabe, T; Takeyama, H; Teranishi, F | 1 |
| Giaccone, G; Peters, GJ; van Groeningen, CJ | 1 |
| Reimer, P; Rückle-Lanz, H | 1 |
| Higashigawa, M; Kagawa, Y; Kakito, H; Kawasaki, H; Kojima, M; Ohkubo, T; Ooi, A; Sakurai, M | 1 |
| Alvarado, A; Alvarez, E; Calvo, FA; Cantalapiedra, R; Díaz-González, JA; García Alfonso, P; Gómez-Espí, M; Herranz, R; Marcos, P | 1 |
| Damle, BD; Kaul, S; Narasimhan, NI | 1 |
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| Borner, MM; Caponigro, F; Comella, G; de Boer, RF; de Wit, R; Fumoleau, P; Greim, G; Martin, C; Peters, GJ; Schoffski, P; Sulkes, A; van der Born, K; Wanders, J | 1 |
| Koyama, S; Shimoda, S; Takeda, N; Tanaka, N; Tsukahara, A; Yajima, K | 1 |
| Gomi, T; Kanaya, S; Katayama, T; Momoi, H; Ohtoshi, M; Tamaki, N; Wada, Y | 1 |
| Holen, KD; Saltz, LB | 1 |
| Aoyagi, K; Basaki, Y; Chikahisa, L; Hashimoto, A; Miyadera, K; Okabe, S; Wierzba, K; Yamada, Y; Yonekura, K | 1 |
| Ioka, Z; Nakane, Y; Nakano, K; Osaka, Y; Sako, H; Takemura, N; Tanabe, S; Tsuchiya, K | 2 |
| Daijo, H; Hoshino, T; Inokuma, S; Ishida, H; Nakada, H; Ohsawa, T; Takeuchi, I | 1 |
| Schöffski, P | 1 |
| Köhne, CH | 1 |
| Araki, S; Asakura, R; Itou, A; Kobayashi, K; Naganuma, J; Teruya, M; Yanagida, O | 1 |
| Hayashi, K; Iijima, S; Koyama, Y; Miyazawa, K; Morikawa, A; Murakami, M; Okabe, R; Ozaki, K; Sugiyama, A; Suzuki, A | 1 |
| Ohta, Y; Shuto, T; Takemura, M; Takemura, S | 1 |
| Croockewit, AJ; de Boer, JE; Koopmans, PP; van Loenhout, JW | 1 |
| Aabo, K; Adimi, P; Hansen, F; Jakobsen, A; Keldsen, N; Kjaer, M; Pfeiffer, P; Sandberg, E | 1 |
| Iizuka, R; Kakihara, N; Matsumura, H; Takahashi, S; Takenaka, A | 1 |
| Sugimura, T | 1 |
| Malet-Martino, M; Martino, R | 1 |
| Benner, SE; Davidson, N; Douillard, JY; Eisenberg, P; Harper, P; Hoff, PM; Lembersky, BC; Maniero, A; Skillings, JR; Thompson, S; Vincent, MD | 1 |
| Borner, M; Carmichael, J; Falk, S; Martin, C; Munier, S; Oza, A; Popiela, T; Radstone, D; Skovsgaard, T | 1 |
| Chinzei, T; Okada, Y; Tasaka, K; Tomofuji, Y | 1 |
| Chiba, M; Hayashi, K; Inaba, Y; Kamio, Y; Koyama, M; Ohe, S; Watabe, S | 1 |
| Hasebe, K; Sasaki, S; Takamura, H; Urade, M; Yagi, M | 1 |
| Azuma, T; Hatada, T; Inoue, Y; Kusunoki, M; Miki, C; Mohri, T; Ojima, E | 1 |
| Badea, I; Moja, D; Stoicescu, D; Tudose, A | 1 |
| Chen, JS; Hsu, KC; Tang, R; Wang, JY; Yang, TS | 1 |
| Eng, C; Kindler, HL; Schilsky, RL | 1 |
| Fukuoka, M; Hamada, M; Kaniwa, N; Matsumoto, Y; Murayama, N; Nakajima, Y; Ohno, Y; Ozawa, S; Sawada, J | 1 |
| Hatada, T; Inoue, Y; Kobayashi, M; Kusunoki, M; Miki, C; Ojima, E | 1 |
| Ishikawa, K; Maeda, Y; Makuuchi, H; Murayama, C; Sadahiro, S; Saguchi, T; Suzuki, T; Yamamoto, T; Yasuda, S | 1 |
| Asaoka, T; Imasato, M; Iwazawa, T; Kanoh, T; Kinuta, M; Matsui, S; Monden, T; Nakano, Y; Okada, K; Okamura, J; Tono, T; Yano, H | 1 |
| Ebuchi, M; Hasegawa, K; Maruyama, M; Nagahama, T; Natui, S; Ochiai, T; Takashima, I | 1 |
| Hashimoto, D; Hoshino, T; Inokuma, S; Ishida, H; Ishizuka, N; Matsumoto, Y; Miura, T; Murata, N; Nakada, H; Odaka, A; Ohsawa, T; Suzuki, T; Takeuchi, I; Yamada, H; Yokoyama, M | 1 |
| Boku, N; Fukuda, H; Hyodo, I; Ikeda, N; Miyata, Y; Ohtsu, A; Saito, H; Shimada, Y; Shirao, K; Yamamichi, N; Yamamoto, S; Yoshida, S | 1 |
| Shimizu, C; Watanabe, T | 1 |
| Nakajima, T; Ohta, K; Ohyama, S; Yamaguchi, T | 1 |
| Kakeji, Y; Kohnoe, S; Maehara, Y | 1 |
| Gochi, A; Hirata, K; Inokuchi, K; Kurosu, Y; Saji, S; Toge, T; Tominaga, S | 1 |
| Ito, T; Kamachi, H; Kamiyama, T; Kondo, M; Kurauchi, N; Matsushita, M; Nakagawa, T; Nishikawa, M; Ogata, T; Todo, S | 1 |
| Gotoh, M; Katsu, K; Kawabe, S; Ohta, S; Takiuchi, H | 1 |
| Ito, T; Kitagawa, T; Kurihara, Y; Morimoto, Y; Nakai, S; Nishimura, J; Tanaka, Y; Yamamoto, S | 1 |
| Hamano, K; Hirohata, S; Inoue, H; Kawaguchi, K; Maeda, T; Matsumoto, I; Nakashima, T; Niki, T; Nishisaki, H; Okutani, T; Sashikata, T; Yasutake, K | 1 |
| Fujiwara, Y; Monden, M; Mori, T; Takiguchi, S; Tamura, S; Yano, M; Yasuda, T | 2 |
| Araki, Y; Inaba, S; Koyama, H; Matsushita, Y; Matsuyama, T; Nakata, M; Ogino, A; Shimizu, T; Yamada, E | 1 |
| Endo, W; Fujito, T; Goda, F; Hojo, S; Maeura, Y; Matsuyama, J; Yamazaki, K; Yano, Y | 1 |
| de Bruin, M; Fukushima, M; Hoekman, K; Kruyt, FA; Peters, GJ; Pinedo, HM; van Capel, T; Van der Born, K | 1 |
| Aldaz, A; Castellanos, C; Giráldez, J; Zufía, L | 1 |
| Glimelius, B | 1 |
| Machida, Y; Nagai, T; Onishi, H; Yoshino, T | 1 |
| Fumoleau, P; Gall, H; Giaccone, G; Holwerda, U; Noordhuis, P; Peters, GJ; Schornagel, JH; Smid, K; Swart, MS; Turner, SL; Van Gennip, AH; Van Groeningen, CJ; Van Kuilenburg, AB; Voorn, D; Wanders, J | 1 |
| Bonneterre, J; Campone, M; Deporte-Fety, R; Fargeot, P; Fumoleau, P; Kerbrat, P; Urien, S | 1 |
| Maehara, Y | 1 |
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| Emi, Y; Kakeji, Y; Kimura, Y; Maehara, Y; Sakurai, M; Takahashi, I; Yonemura, Y | 1 |
| Hayashi, T; Iijima, S; Kato, T; Kikkawa, N; Kimura, Y; Kurokawa, E; Naoi, Y; Tanigawa, T; Yamamoto, H | 1 |
| Goda, F; Hagiike, M; Ishimura, K; Izuishi, K; Karasawa, Y; Maeta, H; Okano, K; Usuki, H; Yachida, S | 1 |
| Abe, K; Fujiwara, H; Gotoh, M; Hoshino, Y; Irinoda, T; Kanzaki, N; Kogure, M; Nakaya, T; Nemoto, T; Ohtani, S; Oyama, K; Saito, K; Takagane, A; Terashima, M; Yonezawa, H | 1 |
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| Kawabata, H; Murata, A; Nakajima, H; Takase, I; Watanabe, T | 1 |
| Ishibiki, Y; Kamano, T; Kawai, K; Matsuda, M; Sasaki, M; Shirasaka, T; Suzuki, Y; Watanabe, T | 1 |
| Hata, K; Hiraga, T; Ikeda, F; Tamura, D; Ueda, A; Williams, PJ; Yoneda, T | 1 |
| Akiyama, N; Arai, F; Funakoshi, K; Inayoshi, J; Kato, T; Kozakai, I; Motoyama, H; Ohta, T; Saito, Y; Takii, Y | 1 |
| Baba, Y; Hayashi, S; Ishikawa, T; Kamimura, T; Nomura, K; Oota, H; Yoshida, T | 1 |
| Goto, M; Hamaguchi, T; Matsumura, Y; Muro, K; Nagayama, S; Shimada, Y; Shirao, K; Yamada, Y | 1 |
| Cho, YS; Kang, JK; Kim, DJ; Kim, NK; Kim, TI; Kim, WH; Shin, SK; Suh, JH | 1 |
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| Azuma, M; Higuchi, K; Kitamura, T; Koizumi, W; Nagaba, S; Nakayama, N; Saigenji, K; Sasaki, T; Tanabe, S | 1 |
| Sato, A; Shimada, K; Taguchi, S | 1 |
| Futamura, N; Matsutomo, M; Sakamoto, K; Tateyama, K; Yasumura, M | 1 |
| Chu, D; Dong, Q; Gu, J; Liu, W; Paul Fawcett, J | 1 |
| Abe, K; Fujiwara, H; Fukushima, M; Irinoda, T; Nakaya, T; Oyama, K; Saito, K; Shirasaka, T; Takagane, A; Takahashi, M; Takechi, T; Terashima, M; Yonezawa, H | 1 |
| Maeda, Y; Sasaki, E; Sasaki, T | 2 |
| Hosokawa, A | 1 |
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| Doi, T; Ohtsu, A | 1 |
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| Brewer, N; Cowan, J; Kaltenthaler, E; Ward, S | 1 |
| Hashimoto, D; Hoshino, T; Inokuma, S; Ishida, H; Itoyama, S; Matsumoto, Y; Miura, T; Mori, T; Murata, N; Nakada, H; Odaka, A; Ohsawa, T; Okada, N; Shirakawa, K; Suzuki, T; Takeuchi, I; Yamada, H; Yokoyama, M | 1 |
| Ebuchi, M; Hasegawa, K; Kato, K; Maruyama, M; Nagahama, T; Shinoura, H; Takashima, I | 1 |
| Handa, R; Iijima, S; Kato, T; Kikkawa, N; Kurokawa, E; Naoi, Y; Oshima, S; Tsujie, M; Yamamoto, H | 1 |
| Furukawa, J; Katsumoto, Y; Kinuta, M; Maruyama, K; Maruyama, N; Nagai, K; Nakaguchi, K; Sue, F; Tanaka, J; Yokouchi, H | 1 |
| Handa, R; Iijima, S; Kato, T; Kikkawa, N; Kurokawa, E; Naoi, Y; Ohshima, S; Tsujie, M; Yamamoto, H | 2 |
| Enomoto, M; Higuchi, T; Sugihara, K; Uetake, H | 1 |
| Kobayashi, M; Konishi, N; Kusunoki, M; Mohri, Y; Ohmori, Y; Tanaka, K; Tonouchi, H | 1 |
| Arikawa, R; Kanekura, T; Kanzaki, T; Uchimiya, H | 1 |
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| Imamura, M; Yamaki, T; Yasuda, M | 1 |
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| Burzykowski, T; Buyse, M; Hamada, C; Ohashi, Y; Piedbois, P; Sakamoto, J | 1 |
| Folprecht, G; Köhne, CH | 1 |
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| Aihara, T; Fukuhara, A; Kouno, T; Murayama, M; Nakagawa, K; Nakamura, E; Niida, M; Nishimoto, Y; Nozaki, H; Syouda, S; Watanabe, Y; Yagyu, T; Yasuoka, H | 1 |
| Artru, P; Desramé, J; Taïeb, J | 1 |
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| Beijnen, JH; Fumoleau, P; Giaccone, G; Holwerda, U; Noordhuis, P; Peters, GJ; Schellens, JH; Schornagel, JH; Schrijvers, A; Van Groeningen, CJ; Voorn, D | 1 |
| Arai, W; Hirashima, Y; Hosoya, Y; Hyodo, M; Nagai, H; Shirasaka, T; Yasuda, Y; Yokoyama, T | 1 |
| Hashimoto, D; Inokuma, S; Ishida, H; Nakada, H; Ohsawa, T; Shirakawa, K; Yamada, H; Yokoyama, M | 1 |
| Au, GK; Chan, RT; Cheng, AC; Choy, DD; Chua, DT; Kwok, CC; Kwong, DL; Kwong, PW; Law, MW; Sham, JS; Wan, KY; Wu, PM; Yau, CC | 1 |
| Ajani, JA; Itoh, N; Itoi, H; Shirasaka, T; Ueda, Y; Yamagishi, H; Yamashita, T | 1 |
| Ferrero, JM; François, E; Milano, G | 1 |
| Formentini, A; Henne-Bruns, D; Kornmann, M | 1 |
| Arakawa, T; Fujiwara, Y; Hamaguchi, M; Higuchi, K; Matsumoto, T; Okazaki, H; Oshitani, N; Sasaki, E; Shiba, M; Suto, R; Tanigawa, T; Tominaga, K; Watanabe, T | 1 |
| Monden, M; Nagano, H; Sakon, M | 1 |
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| Hirakawa, K; Nakata, B; Yamagata, S | 1 |
| Hashimoto, K; Hitsuda, Y; Igishi, T; Kodani, M; Kurai, J; Makino, H; Matsumoto, S; Nakanishi, H; Shigeoka, Y; Shimizu, E; Takeda, K; Touge, H; Yasuda, K | 1 |
| Baba, Y; Ishikawa, T; Kamimura, T; Mizuno, K; Oota, H; Watanabe, K; Yoshida, T | 1 |
| Aoyagi, K; Imaizumi, T; Koufuji, K; Miyagi, M; Shirouzu, K; Takeda, J; Yano, S | 1 |
| Fukunaga, K; Kawai, M; Kotobuki, T; Niinobu, T; Taniguchi, H; Yamamoto, M | 1 |
| Dono, K; Hashimoto, K; Kubota, M; Marubashi, S; Miyamoto, A; Monden, M; Nagano, H; Nakamori, S; Sakon, M; Takahashi, H; Umeshita, K; Yamamoto, S | 1 |
| Ebuchi, M; Hasegawa, K; Kato, K; Koide, A; Maruyama, M; Maruyama, S; Ohbu, M; Takashima, I | 1 |
| Fujitani, K; Hirao, M; Ikenaga, M; Kashiwazaki, M; Masuda, N; Mishima, H; Sawamura, T; Takeda, Y; Takeno, A; Tsujinaka, T | 1 |
| Ebisui, C; Fujimoto, T; Fukuchi, N; Hasuike, Y; Hayashi, N; Izawa, H; Izumiyama, K; Koshino, T; Sakita, I; Soma, I; Yoshida, T | 1 |
| Damdinsuren, B; Dono, K; Kondo, M; Marubashi, S; Miyamoto, A; Monden, M; Nagano, H; Nakamori, S; Nakamura, M; Ota, H; Sakon, M; Umeshita, K; Wada, H; Yamamoto, T; Yang, Y | 1 |
| Iishi, H; Narahara, H; Sugimoto, N; Tatsuta, M | 1 |
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| Inada, K; Ishikawa, T; Kamoshida, S; Maeda, K; Matsuoka, H; Shimomura, R; Tsutsumi, Y | 1 |
| Enomoto, M; Higuchi, T; Iida, S; Sugihara, K; Tsunozaki, H; Uetake, H; Yasuno, M | 1 |
| Hirohashi, Y; Matsuyama, S; Sumi, K | 1 |
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| Endo, Y; Fukushima, T; Kanazawa, M; Ohki, S; Ohshima, T; Saito, M; Sekikawa, K; Takenoshita, S | 1 |
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| del Giglio, A; Lima, AP | 1 |
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| Ishikawa, T; Kamimura, T; Mizuno, K; Ohta, H; Seki, K; Togashi, T; Watanabe, K; Yoshida, T | 2 |
| Asama, T; Ashida, T; Ayabe, T; Chisato, N; Ebisawa, Y; Kamiya, K; Kasai, S; Kohgo, Y; Kono, T; Tomita, I | 1 |
| Hayakawa, K; Miyake, K; Morimoto, T; Mukaihara, S; Nishino, M | 1 |
| Fujioka, A; Fukushima, M; Ikeda, K; Kitazato, K; Nakagawa, F; Ohshimo, H; Okabe, H; Takechi, T | 1 |
| Hatakeyama, K; Muneoka, K; Okumura, S; Shirai, Y; Wakai, T; Yokoyama, N | 1 |
| Hirakawa, N; Komune, S; Kuratomi, Y; Masuda, M; Nakamura, K; Nakashima, T; Shioyama, Y; Umezaki, T; Yamamoto, T | 1 |
| Fujita, S; Okajima, S; Ooka, M; Tanaka, N; Tanaka, T | 1 |
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| Fujii, H; Hasegawa, S; Hatano, E; Ikai, I; Kawashima, K; Matsumoto, S; Satoh, S; Shimahara, Y | 1 |
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| Arcusa, A; Batiste-Alentorn, E; Boleda, M; Campos, JM; Cirera, L; de Mendizábal, EV; de Olaguer, JP; Escudero, P; Galan, A; Guasch, I; Losa, F; Manzano, H; Méndez, M; Nogué, M; Saigí, E; Salud, A; Vicente, P | 1 |
| Hosoda, S; Kamano, T; Miyakawa, A; Okuzawa, A; Sakamoto, K; Sakamoto, S; Yurimoto, S | 1 |
| Bisgaard, C; Hansen, JW; Jakobsen, A; Lindebjerg, J; Mortensen, JP; Rafaelsen, SR | 1 |
| Kobayashi, O; Tsuburaya, A; Yoshikawa, T | 1 |
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| Goto, T; Hayashi, T; Irimura, K; Kouchi, Y; Morinaga, H; Moriyama, K; Ohuchida, A; Yoshizawa, Y | 1 |
| Bando, E; Endou, Y; Kawamura, T; Miyamoto, K; Sasaki, T; Shimada, T; Tanaka, M; Tochiori, S; Yonemura, Y | 1 |
| Fujimoto, T; Ishibashi, K; Ogawa, K; Umehara, A; Watanabe, K; Yokomizo, H; Yoshida, K; Yoshimatsu, K | 1 |
| Fuji, N; Itoh, T; Kurioka, H; Shirasaka, T; Ueda, Y; Yamagishi, H; Yamashita, T | 1 |
| Alvarez, E; Calvo, FA; Cortés, J; Del Valle, E; Díaz-González, JA; García-Sabrido, JL; Gómez-Espí, M; Muñoz-Jiménez, F | 1 |
| Ikeda, M; Morizane, C; Okusaka, T; Ueno, H | 1 |
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| Kamano, T; Kawai, K; Kitajima, M; Ochiai, T; Sakamoto, K; Shirasaka, T; Tsuruoka, Y; Watabe, S | 1 |
| Fukushima, M; Konishi, K; Mizuiri, H; Sakata, Y; Suzuki, T; Tanabe, K; Ukon, K; Wada, Y; Yoshida, K | 1 |
| Asanuma, F; Atsuda, K; Etou, T; Hiraku, O; Masuda, A; Miyagawa, T; Morinaga, S; Osaku, M; Sasaki, K; Suzuki, T; Suzuki, Y; Tongu, M; Yamada, T; Yamada, Y | 1 |
| Abad, A; Aranda, E; Carrato, A; Cervantes, A; Díaz-Rubio, E; Tabernero, J | 1 |
| Colangelo, LH; Colman, LK; Giguere, JK; Jacobs, AD; Lembersky, BC; Marshall, ME; O'Connell, MJ; Petrelli, NJ; Seay, TE; Smith, RE; Soran, A; Wieand, HS; Wolmark, N; Yothers, G | 1 |
| Alvarez, E; Arranz, JA; Calvo, FA; de la Mata, D; Diaz-González, JA; Garcia, R; García-Alfonso, P; Gomez-Espi, M; Lozano, E; Pérez-Manga, G; Serrano, FJ | 1 |
| Ishigame, T; Ishii, Y; Okayama, H; Takahashi, M | 1 |
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| Hirayama, R; Ichikawa, W; Nihei, Z; Sasaki, Y; Shimizu, M; Shirota, Y; Suto, K; Takahashi, T | 1 |
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| Arias de la Vega, F; Arraras Urdaniz, JI; Manterola Burgaleta, A; Martínez Aguillo, M; Salgado Pascual, E; Vera García, R; Villafranca Iturre, E | 1 |
| Cowan, J; Kaltenthaler, E; Marples, M; Orr, B; Seymour, MT; Ward, SE | 1 |
| Hatori, S; Imada, T; Kunisaki, C; Oshima, T; Yamada, R | 1 |
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| Kobayashi, H; Koike, T; Kurashina, K; Kurita, H; Miyazawa, H; Uehara, S | 1 |
| Kanamaru, T; Tanaka, K; Yamamoto, M | 1 |
| Fukushima, M; Milas, L; Nakamura, Y; Nakata, E; Nemoto, K; Nomiya, T; Ogawa, Y; Takai, Y; Yamada, S | 1 |
| Dono, K; Hayashi, N; Monden, M; Nagano, H; Nakahira, S; Nakamori, S; Okami, J; Sakon, M; Takahashi, Y; Takeda, S; Tsujie, M; Umeshita, K | 1 |
| Aldaz, A; Alvarado, A; Arranz, JA; Calvo, FA; de la Mata, D; García, R; Giráldez, J; Serrano, J; Zufía, L | 1 |
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| Shirasaka, T; Taguchi, T | 1 |
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| Furuhata, T; Hirata, K; Horikoshi, N; Ishizuka, H; Nakano, Y; Okazaki, M; Sasaki, K; Shirasaka, T; Sohma, K; Taguchi, T; Tominaga, K; Uno, S; Yamada, Y; Yamaguchi, K; Yamamitsu, S | 1 |
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| Horiuchi, C; Ishitoya, J; Katori, H; Matsuda, H; Mikami, Y; Taguchi, T; Toth, G; Tsukuda, M; Yoshida, T | 1 |
| Hirata, K; Hiyama, S; Inui, N; Kimura, H; Kimura, Y; Shirasada, T; Yamada, Y; Yamamitsu, S | 1 |
| Aoki, M; Ebina, A; Hoshi, Y; Ishiguro, A; Mitobe, S; Munakata, M; Okada, R; Sakata, Y; Shitara, K; Tomioka, R | 1 |
| Harlak, A; Lembersky, BC; Nesbitt, L; O'Connell, MJ; Soran, A; Wienad, HS; Wilson, JW | 1 |
| Honda, J; Miyoshi, T; Seike, J; Tangoku, A; Umemoto, A; Yoshida, T | 2 |
| Fujiwara, T; Gouchi, A; Kagawa, S; Matsuoka, J; Nishizaki, M; Tanaka, N; Teraishi, F; Tokunaga, N; Uno, F | 1 |
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| Aikou, T; Haraguchi, Y; Ikeda, N; Kamikado, C; Sakamoto, F; Toyoyama, H; Ueno, S | 1 |
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| Chao, TC; Chen, WS; Lin, PC; Liu, JH; Tiu, CM; Yang, SH | 1 |
| Amano, M; Fujita, M; Hayashida, H; Higaki, N; Nakagawa, S; Niinobu, T; Nishikawa, Y; Sakon, M; Yamashita, S | 1 |
| Ebisui, C; Fujimoto, T; Fujiwara, S; Fukuchi, N; Hasuike, Y; Hayashi, N; Sakita, I; Tsujie, M; Yoshida, T | 1 |
| Fujino, K; Ishikubo, T; Shimamura, T; Tada, M; Yamaguchi, K | 1 |
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| Cecchini, RS; Ganz, PA; Kopec, JA; Land, SR; Lembersky, BC; Wieand, HS; Wolmark, N; Yothers, G | 1 |
| Matsukawa, M; Sato, A | 1 |
| Ikeguchi, M; Katano, K; Murakami, D; Osaki, T; Saito, H; Tatebe, S; Tsujitani, S | 1 |
| Akagawa, T; Fujioka, S; Hara, T; Hiramatsu, K; Hirata, A; Ito, T; Kato, K; Kutsuna, Y; Machiki, Y; Matsuba, H; Miyata, T | 1 |
| Hyodo, I | 1 |
| López-Brea, MF; Rivera, F; Vega-Villegas, ME | 1 |
| Gega, M; Hashimoto, A; Ikeuchi, H; Kuno, T; Noda, M; Oshima, T; Tanaka, K; Tsukamoto, K; Yagyuu, T; Yamamura, T; Yanagi, H; Yoshikawa, R | 1 |
| Almond, J; Ralston, S | 1 |
| Iwasaki, Y; Miyake, Y; Sakaguchi, K; Shiraha, H; Shiratori, Y | 1 |
| Kim, R; Saif, MW | 1 |
| Ando, T; Maruoka, Y; Ogiuchi, H; Ogiuchi, Y | 1 |
| Komatsu, Y | 1 |
| Fukushima, M; Maruyama, R; Nio, Y; Toga, T | 1 |
| Fuchimoto, M; Fujikura, H; Hato, S; Higashida, M; Hirabayashi, Y; Hirai, T; Kawabe, Y; Matsumoto, H; Murakami, H; Tsunoda, T; Urakami, A; Yamashita, K | 1 |
| Doi, K; Kudo, K; Matsuo, A; Ogata, K; Ohchi, T; Ootao, R | 1 |
| Baba, H; Maehara, Y; Matsui, T; Morita, S; Sakamoto, J; Takiuchi, H; Tsuburaya, A | 1 |
| Hori, S; Inoue, S; Ohtani, H; Sawada, Y; Tsujimoto, M | 1 |
| Ae, T; Higuchi, K; Ishido, K; Katada, C; Koizumi, W; Nakatani, K; Saigenji, K; Sasaki, T; Tanabe, S | 1 |
| Furuse, J; Ishii, H; Nakachi, K; Shimizu, S; Suzuki, E | 1 |
| Murakami, S; Yamamoto, Y | 1 |
| Cardot, JM; Douillard, JY; Etienne-Grimaldi, MC; François, E; Gamelin, E; Milano, G; Renée, N | 1 |
| Boku, N; Koizumi, W; Nagashima, F; Ohtsu, A; Shirao, K | 1 |
| Baehring, JM; Fulbright, RK | 1 |
| Hirakawa, K; Kim, WY; Nakata, B | 1 |
| Aizaki, K; Fujii, M; Kaiga, T; Kanamori, N; Kochi, M; Takahashi, T; Takayama, T | 1 |
| Date, H; Fujiwara, Y; Hotta, K; Kiura, K; Matsuo, K; Ouchida, M; Soh, J; Suehisa, H; Takata, M; Toyooka, S; Uchida, A | 1 |
| Arias, F; Belinchón, B; de la Fuente, C; de la Torre, A; Fernández-Lizarbe, E; García-Berrocal, MI; Magallón, R; Mariño, A; Millán, I; Molerón, R; Regueiro, CA; Romero, J; Valcárcel, F; Veiras, M; Vergara, G; Zapata, I | 1 |
| Del Valle, A; Galdós, P; García-Montesinos, B; García-Reija, F; Isla, D; López-Brea, M; Mayordomo, J; Mayorga, M; Rama, J; Rivera, F; Rodríguez-Iglesias, J; Rubio, A; Saiz-Bustillo, R; Sanz-Ortiz, J; Vega-Villegas, ME | 1 |
| Ajani, JA; Cen, P | 1 |
| Imai, M; Ishikawa, T; Kamimura, H; Kamimura, T; Ohta, H; Seki, K; Togashi, T; Tsuchiya, A; Watanabe, K; Yoshida, T | 1 |
| Bennouna, J; Cardot, JM; Château, Y; Douillard, JY; Etienne-Grimaldi, MC; François, E; Gamelin, E; Milano, G; Renée, N | 1 |
| Hirata, K; Hiyama, S; Inui, N; Kimura, H; Kimura, Y; Shirasaka, T; Yamada, Y; Yamaguchi, K; Yamamitsu, S | 1 |
| Baba, K; Matsuda, M; Tashima, R; Yamashita, Y; Yokoyama, S | 1 |
| Arakawa, T; Fujiwara, Y; Higuchi, K; Kuwamura, H; Oshitani, N; Sasaki, E; Tominaga, K; Watanabe, T | 1 |
| Boku, N; Funakoshi, A; Furuse, J; Nagase, M; Ohkawa, S; Okusaka, T; Saisho, H; Sato, T; Tanaka, K; Yamao, K; Yonemoto, N | 1 |
| Isogai, A; Kubota, S; Matsuoka, H; Nagaya, M; Tsukikawa, S; Watanabe, T | 1 |
| Liu, Q; Nie, L; Tao, W; Yang, Y; Yao, S | 1 |
| Geboes, K; Van Cutsem, E | 1 |
| Nakano, T; Tomimatsu, H | 1 |
| Hasegawa, H; Kanekiyo, S; Kubo, H; Tada, K; Watanabe, Y | 1 |
| Brugnatelli, S; Corazza, GR; Gattoni, E; Luchena, G; Riccardi, A; Sagrada, P; Scalamogna, R; Tinelli, C; Tronconi, MC | 1 |
| Chida, K; Inui, N; Kaida, Y; Nakamura, H; Suda, T; Watanabe, H | 1 |
| Doki, Y; Fujiwara, Y; Miyata, H; Monden, M; Nishida, T; Takiguchi, S; Yamazaki, M | 1 |
| Arias, JL; Delgado, AV; Gallardo, V; Linares-Molinero, F | 1 |
| Aykan, NF; Idelevich, E | 1 |
| Cascinu, S | 1 |
| Cheng, SX; Yu, CY; Zhang, XC; Zhang, XZ; Zhou, FZ; Zhuo, RX | 1 |
| Chang, PM; Chang, SY; Chen, PM; Chu, PY; Huang, JL; Tai, SK; Tsai, TL; Wang, LW; Wang, YF; Yang, MH | 1 |
| Han, CJ | 1 |
| Akiyama, Y; Ando, Y; Araki, K; Endo, H; Endo, S; Fujita, K; Ichikawa, W; Kamataki, T; Kawara, K; Kodama, K; Miwa, K; Miya, T; Nagashima, F; Narabayashi, M; Sasaki, Y; Sunakawa, Y; Tanaka, R; Yamamoto, W | 1 |
| Fujita, K; Ichikawa, W; Sasaki, Y | 1 |
| Honda, J; Matsuoka, H; Miyoshi, T; Seike, J; Tangoku, A; Yamai, H; Yoshida, T; Yuasa, Y | 1 |
| Akiyama, S; Fukushima, M; Oka, T; Ooyama, A; Yamamoto, M; Zhao, HY | 1 |
| Fujimoto, K; Hirao, Y; Okajima, E; Ozono, S; Tsujimoto, S | 1 |
| Hayashi, S; Karaki, H; Sugano, I; Sugimoto, K; Suzuki, H; Takayanagi, H; Yamamori, H; Yamamoto, K | 1 |
| Inaba, K; Isogaki, J; Kamoshida, S; Komori, Y; Sakurai, Y; Tsutsumi, Y; Uyama, I; Yoshida, I | 1 |
| Masai, Y; Nakagawa, T; Nibu, K; Otsuki, N; Sasaki, R; Tsukuda, M | 1 |
| Barone, C; Pozzo, C | 1 |
| Baek, JH; Chang, HM; Kang, HJ; Kang, WK; Kang, YK; Kim, JG; Kim, TW; Lee, JL; Lee, KH; Min, YJ; Park, SR; Ryoo, BY; Ryu, MH; Shin, DB; Zang, DY | 1 |
| Hizawa, K; Iida, M; Matsumoto, T; Nagata, Y; Nakamori, M; Taniguchi, M | 1 |
| Hoshino, S; Maekawa, T; Mikami, K; Sakai, T; Shirakusa, T; Yamashita, Y | 1 |
| Hatake, K; Ito, Y; Iwase, T; Osaki, Y; Sugihara, T; Takahashi, S; Tokudome, N | 1 |
| Bekaii-Saab, T; Haghighat, P | 1 |
| Kobayashi, Y; Matsuzaki, A; Terauchi, F; Washino, S | 1 |
| Dai, GH; Jiao, SC; Li, F; Li, Y; Liu, W; Lu, HS; Niu, RG; Song, SP; Wang, J; Xie, XD; Xu, JM; Yang, JL; Zhang, FC; Zhang, Y; Zhao, H | 1 |
| Cho, GJ; Choi, YJ; Chung, JS; Kim, GH; Seol, YM; Shin, HJ; Song, GA; Song, MK | 1 |
| Aoki, K; Hoshikawa, K; Nitta, H; Noda, H; Oyama, K; Wakabayashi, G | 1 |
| Hamaguchi, T; Hirashima, Y; Honda, T; Kato, K; Matsubara, J; Okita, NT; Shimada, Y; Shimoda, T; Shirao, K; Takahari, D; Takashima, A; Yamada, Y | 1 |
| Ariche, A; Baruch, NB; Brenner, B; Dinerman, M; Greif, F; Idelevich, E; Kashtan, H; Mavor, E; Miller, R; Shani, A; Susmalian, S | 1 |
| Bang, YJ; Heo, DS; Im, SA; Kim, DW; Kim, MJ; Kim, TY; Lee, SH; Oh, DY | 1 |
| Arai, W; Haruta, H; Hirashima, Y; Hosoya, Y; Hyodo, M; Kurashina, K; Nagai, H; Saito, S; Sakuma, K; Shirasaka, T; Yasuda, Y; Yokoyama, T; Zuiki, T | 1 |
| Aiba, K; Ishida, Y; Kawakami, M; Kitajima, K; Kobayashi, S; Shiba, H; Uwagawa, T; Yanaga, K | 1 |
| Hanamura, H; Horiuchi, C; Kawakami, M; Matsuda, H; Mikami, Y; Nishimura, G; Satake, K; Taguchi, T; Takahashi, M; Tsukuda, M; Utsumi, A; Watanabe, M | 1 |
| Agata, T; Aoyama, H; Funahashi, M; Hanai, T; Honda, K; Katsuno, H; Koide, Y; Maeda, K; Matsuoka, H; Noro, T; Sato, H; Shiota, M | 1 |
| Akagi, K; Fujita, J; Hata, T; Hayashi, S; Ikeda, K; Kagawa, Y; Kato, H; Kawanishi, K; Kitada, M; Maeda, S; Nomura, M; Oshima, N; Sasaki, T; Shimano, T; Shimizu, J; Takamoto, K; Tsukahara, Y | 1 |
| Choi, GS; Jun, SH; Kang, BM; Lim, KH; Park, IJ | 1 |
| Fukuoka, M; Hatashita, E; Jänne, PA; Nakagawa, K; Nishio, K; Okabe, T; Okamoto, I; Tsukioka, S; Uchida, J; Yamada, Y; Yoshida, T | 1 |
| Azuma, T; Chayahara, N; Hirai, M; Inoue, Y; Kadowaki, Y; Kasuga, M; Maeda, T; Miki, I; Nishisaki, H; Okumura, K; Okuno, T; Sakaeda, T; Tamura, T; Tsuda, M; Yamamori, M | 1 |
| Hanauske, A; Hilger, RA; Krauss, J; Kredtke, S; Makris, L; Mende, B; Scheulen, ME; Scigalla, P; Strumberg, D; Thyssen, D; Urrea, PD | 1 |
| Iwata, H; Kitaya, T; Kohno, N; Nakagami, K; Ohashi, Y; Sakamoto, G; Sano, M; Shimozuma, K; Sonoo, H; Takashima, S; Tokuda, Y; Tsuda, H; Watanabe, T; Yoshimoto, M | 1 |
| Boku, N; Fukutomi, A; Hironaka, S; Kojima, T; Ono, A; Onozawa, Y; Taku, K; Yamazaki, K; Yasui, H; Yoshino, T | 1 |
| Asanuma, F; Atsuda, K; Hiraku, O; Inoue, G; Morimoto, Y; Sasaki, K; Suzuki, Y; Takeuchi, O; Takizawa, A; Yamada, Y; Yoshizawa, J | 1 |
| Akiyama, Y; Ando, Y; Araki, K; Endo, H; Fujita, K; Hirose, T; Ichikawa, W; Ishida, H; Kawara, K; Miwa, K; Miya, T; Mizuno, K; Nagashima, F; Nakayama, H; Narabayashi, M; Sasaki, Y; Sunakawa, Y; Tanaka, R; Yamamoto, W; Yamashita, K | 1 |
| Hamada, A; Saito, H; Sasaki, Y; Tazoe, K; Yokoo, K | 1 |
| Shuler, ML; Sung, JH | 1 |
| Hamaguchi, T; Hirashima, Y; Kato, K; Matsubara, J; Okita, NT; Shimada, Y; Shimoda, T; Shirao, K; Takahari, D; Taniguchi, H; Yamada, Y | 1 |
| Huh, JW; Kim, HR | 1 |
| Azuma, M; Higuchi, K; Ishido, K; Katada, C; Koizumi, W; Nakatani, K; Nakayama, N; Nishimura, K; Sasaki, T; Tanabe, S | 1 |
| Chen, XQ; He, YJ; Li, YH; Pan, ZZ; Qiu, MZ; Ruan, DY; Teng, KY; Wan, DS; Xu, RH | 1 |
| Asaga, T; Higaki, K; Inaji, H; Ito, T; Koh, J; Kohno, N; Komichi, H; Koyama, H; Kyono, S; Mitsuyama, S; Nishikawa, H; Ogita, M; Okamura, K; Osaki, A; Park, Y; Saito, T; Suzuki, T; Tanaka, F; Yamazaki, K | 1 |
| Asaka, Y; Hatakeyama, D; Kato, K; Kato, Y; Long, NK; Makita, H; Miyazaki, Y; Shibata, T; Toida, M; Yamashita, T; Yonemoto, K | 1 |
| Ioue, Y; Kusunoki, M; Miki, C; Okugawa, Y; Saigusa, S; Tanaka, K; Toiyama, Y; Yokoe, T | 1 |
| Cho, YB; Chun, HK; Kim, HC; Lee, WY; Yun, HR; Yun, SH | 1 |
| Kusano, M; Matsui, N; Nakao, K; Narita, K; Tsunoda, A; Watanabe, M; Yasuda, N | 1 |
| Hibino, M; Kitamura, T; Nakamura, M; Okuyama, M; Sasaki, Y; Shindo, Y; Tenma, K | 1 |
| Teng, KY; Xu, RH | 1 |
| Boku, N; Doi, T; Fukuda, H; Koizumi, W; Nasu, J; Ohtsu, A; Saito, H; Sawaki, A; Shirao, K; Takiuchi, H; Yamaguchi, K; Yamamoto, S | 1 |
| Nishida, T | 1 |
| Fujii, M; Funada, T; Kaiga, T; Kanamori, N; Kochi, M; Takahashi, T; Takayama, T | 1 |
| Inaji, H; Koyama, H; Ohashi, Y; Sano, M; Suzuki, T; Watanabe, T | 1 |
| Chikamoto, J; Kanie, S; Nagayama, S; Nishimura, T; Yoshisue, K | 1 |
| Akboru, H; Bati, Y; Isikli, L; Unsal, M; Yoney, A | 1 |
| Takiuchi, H | 1 |
| Hara, T; Hiramatsu, K; Hosoya, J; Kato, K; Kimura, A; Kojima, T; Machiki, Y; Otsuji, H; Sakuragawa, T; Tanaka, H; Tsuchiya, T; Yoshida, K | 1 |
| Doi, K; Hirano, Y; Ishihara, A; Kojima, K; Kudo, K; Ochi, T; Ogata, K | 1 |
| Inoue, S; Nasu, K; Noda, K; Umekita, N | 1 |
| Akabane, H; Hanamoto, T; Kita, K; Kuji, M; Miyagi, H; Nakano, S; Oikawa, F; Shomura, H; Takahashi, M; Yanagida, N | 1 |
| Doki, Y; Eguchi, H; Hatano, H; Kobayashi, S; Marubashi, S; Mori, M; Murakami, M; Nagano, H; Takeda, Y; Tanemura, M; Tomimaru, Y; Tomokuni, A; Wakasa, K | 1 |
| Fukumori, D; Kamachi, H; Kamiyama, T; Matsushita, M; Nakagawa, T; Nakanishi, K; Tahara, M; Todo, S; Yokoo, H | 1 |
| Aoyagi, H; Hamada, S; Kaneko, J; Katsuta, E; Maejima, S; Makinose, T; Okubo, K; Saguchi, M; Sato, T; Sekine, T; Someno, Y; Sugihara, K | 1 |
| Arimori, K; Hanada, N; Hidaka, H; Hidaka, M; Kawaguchi, H; Kawano, Y; Nakamura, C; Tomiyama, N | 1 |
| Bin, Q; Cao, Y; Gao, F; Li, J; Liao, C | 1 |
| Nakayama, T; Noguchi, S | 1 |
| Kubo, N; Matuoka, T; Nobuhara, Y; Yo, T | 1 |
| Chen, X; Liu, K; Zhong, D; Zou, H | 1 |
| Ajani, JA; Bodoky, G; Falcon, S; Garin, A; Gorbunova, V; Lang, I; Lichinitser, M; Moiseyenko, V; Rodriguez, W; Vynnychenko, I | 1 |
| Amano, R; Hirakawa, K; Hirakawa, T; Nakao, S; Nakata, B; Okita, Y; Shinto, O; Tamura, T; Yamada, N | 1 |
| Aka, H; Hanashiro, N; Kiyuna, M; Matsuura, F; Miyahira, T; Murayama, S; Nishihara, M; Okushima, N; Teruya, J; Teruya, N; Toda, Y | 1 |
| Barattè, S; Breda, M | 1 |
| Gemma, A; Kataoka, K; Matsuda, K; Minegishi, Y; Miyanaga, A; Noro, R; Okano, T; Seike, M; Soeno, C; Yoshimura, A | 1 |
| Fukuoka, M; Kiniwa, M; Nakagawa, K; Okamoto, I; Takezawa, K; Tanizaki, J; Tsukioka, S; Uchida, J | 1 |
| Matsushima, E; Nagayama, S; Yamamiya, I; Yoshisue, K | 1 |
| Matsumoto, H; Mori, T; Takahashi, K; Yamaguchi, T; Yasutome, M | 1 |
| Hirai, T; Ito, Y; Kato, T; Kodera, Y; Nakanishi, H; Nakao, A | 1 |
| Kawai, K; Kitayama, J; Nagawa, H; Sunami, E; Yasuda, K | 1 |
| Fukuoka, M; Kuwata, K; Nakagawa, K; Nishio, K; Okamoto, I; Takezawa, K; Tanizaki, J; Yamaguchi, H | 1 |
| Cao, Y; Gao, F; He, Y; Huang, J; Liao, C; Wu, L | 1 |
| Adachi, M; Fujita, K; Hirose, T; Ishida, H; Miwa, K; Mizuno, K; Nagashima, F; Nishimura, K; Sasaki, Y; Sunakawa, Y; Tanigawara, Y; Yamashita, K | 1 |
| Hashiguchi, K; Hiraki, M; Kai, K; Kitajima, Y; Miyazaki, K; Nakamura, J; Noshiro, H; Tokunaga, O | 1 |
| Altman, RB; Carrillo, MW; Klein, TE; Marsh, S; McLeod, HL; Thorn, CF | 1 |
| Harada, K; Itashiki, Y; Takenawa, T; Ueyama, Y | 1 |
| Atsumi, K; Higaki, Y; Hirata, H; Honda, H; Nakamura, K; Ohnishi, K; Ohura, H; Sasaki, T; Shinoto, M; Shioyama, Y; Toh, Y; Yamaguchi, T | 1 |
| Baba, H; Boku, N; Denda, T; Esaki, T; Hyodo, I; Ina, K; Komatsu, Y; Kuwano, H; Morita, S; Muro, K; Nishina, T; Sameshima, S; Satoh, T; Shimada, Y; Sugihara, K; Takiuchi, H; Tokunaga, S; Tsuji, A; Watanabe, M; Yamaguchi, K | 1 |
| Hatakeyama, K; Kanda, J; Muneoka, K; Sakata, J; Sasaki, M; Shirai, Y; Wakabayashi, H; Wakai, T | 1 |
| Ahn, JY; Chung, HC; Hyung, WJ; Jeung, HC; Lee, SS; Noh, SH; Rha, SY | 1 |
| Abe, M; Kiniwa, M; Matsuo, K; Nakagawa, F; Noguchi, S; Nukatsuka, M; Saito, H; Shibata, J; Uchida, J | 1 |
| Fukushima, M; Nakagawa, F; Ohshimo, H; Sakamoto, K; Taguchi, T | 1 |
| Schmoll, HJ | 1 |
| Harada, Y; Kawai, T; Miyazaki, I; Moriyasu, F | 1 |
| Fukushima, M; Nakagawa, F; Saito, H; Sakamoto, K; Sakata, M; Sakata, Y | 1 |
| Iwase, S; Kitamura, K; Kuroda, Y; Nagumo, Y; Odagiri, H; Yamamoto, C; Yamamoto, D; Yoshida, H | 1 |
| Fujitani, K; Hasegawa, H; Hirao, M; Kurokawa, Y; Mita, E; Nakazuru, S; Tsujinaka, T | 1 |
| Karaho, T; Kogashiwa, Y; Kohno, N; Maruyama, T; Matsuda, T; Nagafuji, H; Tsubosaka, T; Yamauchi, K | 1 |
| Bou, H; Kanno, H; Kiyama, T; Maejima, K; Suzuki, H; Tokunaga, A; Uchida, E; Watanabe, M | 1 |
| Boot, H; Cats, A; Deenen, MJ; Schellens, JH; Terpstra, WE | 1 |
| Inoue, H; Murakami, M; Nishizaki, T; Shimabukuro, R; Shiraishi, T; Takahashi, I; Yano, H | 1 |
| Haba, R; Huang, CL; Kadota, K; Liu, D; Wada, H; Yokomise, H | 1 |
| Inaba, Y; Kato, M; Kawai, H; Komatsu, Y; Muro, K; Sato, Y; Shitara, K; Tajika, M; Takahari, D; Utsunomiya, S; Yamaura, H; Yamazaki, K; Yokota, T; Yoshida, M; Yuki, S | 1 |
| Asano, A; Hirasawa, N; Horikawa, Y; Ishihara, S; Itoh, Y; Koyama, K; Murao, T; Naganawa, S; Nomoto, Y; Obata, Y; Sasaoka, M; Suzuki, K | 2 |
| Akagi, K; Douno, K; Fujino, S; Fujita, J; Hata, T; Ikeda, K; Iwazawa, T; Kawanishi, K; Kitada, M; Kitahara, T; Miyake, M; Munakata, K; Shimano, T; Shimizu, J; Takamoto, K; Watanabe, N; Yanagawa, T | 1 |
| Doki, Y; Hirose, H; Ikeda, M; Ishii, H; Kim, HM; Miyoshi, N; Mizushima, T; Mori, M; Okano, M; Sekimoto, M; Takemasa, I; Uemura, M; Yamamoto, H; Yamashita, S | 1 |
| Doki, Y; Hirose, H; Ikeda, M; Kim, HM; Miyoshi, N; Mizushima, T; Mori, M; Okano, M; Sekimoto, M; Takemasa, I; Yamamoto, H; Yamashita, S | 1 |
| Aoyagi, H; Hamada, S; Hasegawa, K; Isogai, J; Kaneko, J; Katsuta, E; Maejima, S; Saguchi, M; Someno, Y; Takahata, T | 1 |
| Gotoh, K; Ishikawa, O; Kano, S; Kishi, K; Miyashiro, I; Motoori, M; Noura, S; Ohigashi, H; Ohue, M; Shingai, T; Takahashi, H; Yamada, T; Yano, M | 1 |
| Asukai, K; Fujimoto, T; Hama, N; Hata, T; Kashiwazaki, M; Konishi, M; Maekawa, T; Nakanishi, M; Okubo, K; Taniguchi, M; Tsujie, M; Yano, K; Yoshioka, S | 1 |
| Asaka, M; Hatanaka, K; Hosokawa, A; Iwanaga, I; Kato, T; Komatsu, Y; Kusumi, T; Miyagishima, T; Nakamura, M; Sakata, Y; Sogabe, S; Yuki, S | 1 |
| Hasegawa, M; Ide, H; Kikuchi, E; Kosaka, T; Maeda, T; Miyajima, A; Oya, M; Shirotake, S; Tanaka, N; Yasumizu, Y | 1 |
| Doi, F; Ishikawa, N; Kusumoto, C; Kusumoto, M; Matsumoto, T; Toyoda, S | 1 |
| Mendelson, DS; Ravage-Mass, L; Rosen, LS; Saif, MW; Saito, K; Zergebel, C | 1 |
| Abe, M; Hashimoto, O; Inoue, K; Iwamoto, H; Kerbel, RS; Koga, H; Kurogi, J; Kuwahara, R; Nakamura, T; Niizeki, T; Sata, M; Torimura, T; Ueno, T; Yano, H | 1 |
| Fujiwara, M; Iwata, N; Kodera, Y; Koike, M; Nakao, A; Nakayama, G; Ohashi, N; Okuda, N; Tanaka, C; Watanabe, T; Yokoyama, H | 1 |
| Bian, T; Chen, C; Chen, Y; Jin, T; Lin, A; Liu, D; Wang, H | 1 |
| Eto, M; Inokuchi, J; Kiyoshima, K; Kuroiwa, K; Naito, S; Shiota, M; Takeuchi, A; Tatsugami, K; Yokomizo, A | 1 |
| Chung, HC; Jeung, HC; Lim, SJ; Noh, SH; Rha, SY; Roh, JK; Shin, SJ | 1 |
| Ajani, JA; Blum, M; Suzuki, A | 1 |
| Kang, WK; Lee, J; Lee, SJ; Lim, HY; Park, JO; Park, SH; Park, YS; Yim, DS | 1 |
| Kaino, S; Kuramitsu, Y; Murakami, K; Nakamura, K; Ryozawa, S; Sakaida, I; Taba, K; Yoshida, K; Zhang, X | 1 |
| Hamada, Y; Horie, A; Iketani, S; Kanai, I; Kawaguchi, K; Nakatani, Y; Nomura, T; Sato, K; Suzuki, S; Yamada, H | 1 |
| Matsueda, S; Sasaki, H; Tokunaga, Y | 1 |
| Giannini, OH; González, ME; González, P; Saldaña, B | 1 |
| Chung, YL; Jen, YM; Lin, YH; Wang, LW; Yen, SH | 1 |
| Boku, N; Brown, KH; Hayashi, H; Muro, K; Nakajima, TE; Satoh, T; Shi, X; Shimada, Y; Takahari, D; Taku, K; Yamada, Y | 1 |
| Enomoto, N; Hosoya, N; Motoyama, K; Oono, R; Otsuki, S; Ueda, Y | 1 |
| Fujikawa, H; Inoue, Y; Kusunoki, M; Matsushita, K; Okugawa, Y; Saigusa, S; Tanaka, K; Toiyama, Y; Uchida, K | 1 |
| Bensadoun, RJ; Hamidou, H; Michel, P; Paillot, B; Roullet, B; Silvain, C; Tougeron, D; Tourani, JM | 1 |
| Fukuda, K; Kawakubo, H; Kitagawa, Y; Saikawa, Y; Takahashi, M; Takahashi, T; Takeuchi, H; Wada, N | 1 |
| Bellot, GL; Koh, D; Tan, WH; Tay, LL; Wang, X | 1 |
| Kato, K | 1 |
| Chung, HC; Jeung, HC; Jung, I; Kim, GM; Kim, HS; Lee, KH; Nam, BH; Rha, SY | 1 |
| Jensen, HA; Pfeiffer, P; Vestermark, LW | 1 |
| Baba, H; Kakeji, Y; Kobayashi, M; Matsui, T; Miyashita, Y; Morita, S; Nishikawa, K; Sakamoto, J; Sato, S; Takahashi, I; Takeuchi, Y; Tsuburaya, A | 1 |
| Kondo, C; Matsuo, K; Mizota, A; Muro, K; Sato, Y; Shitara, K; Tajika, M; Takahari, D; Ura, T | 1 |
| Kondo, C; Matsuo, K; Muro, K; Niwa, Y; Sawaki, A; Shitara, K; Tajika, M; Takahari, D; Ura, T | 1 |
| Hurwitz, HI; McManus, TJ; Peer, CJ; Petros, WP | 1 |
| Ishibashi, N; Kibe, S; Murakami, N; Ogata, Y; Shirouzu, K; Takahashi, K; Takeuchi, M; Uchida, S; Yahara, T | 1 |
| Appelt, A; Jakobsen, A; Lindebjerg, J; Ploen, J; Rafaelsen, SR; Vuong, T | 1 |
| Cheng, AL; Hsu, CH; Huang, CC; Lin, SD; Shao, YY | 1 |
| Hasegawa, H; Hisa, A; Kitagawa, Y; Ohishi, T; Okabayashi, K; Watanabe, M | 1 |
| Ando, Y; Fujimoto, Y; Fujita, K; Hiramatsu, M; Inada, M; Kawada, K; Mitsuma, A; Morita, S; Yasuda, Y | 1 |
| Kobunai, T; Nakagawa, F; Nukatsuka, M; Saito, H; Sakamoto, K; Shiraishi, K; Takechi, T; Uchida, J | 1 |
| Kobayashi, M; Kodera, Y; Morita, S; Sakamoto, J; Shitara, K; Tsuburaya, A; Yamaguchi, K; Yoshida, K; Yoshikawa, T; Yoshino, S | 1 |
| Bernstine, H; Brenner, B; Goldberg, N; Gordon, N; Groshar, D; Idelevich, E; Kundel, Y; Morgenstern, S; Purim, O; Sulkes, A; Wasserberg, N | 1 |
| Sakata, Y; Satoh, T | 1 |
| Baek, JH; Cho, SH; Choi, YH; Chung, IJ; Hong, YS; Jeung, HC; Kang, HJ; Kim, BS; Kim, JS; Nam, SH; Oh, SC; Song, EK; Yang, SH; Yim, CY | 1 |
| Hirashima, T; Imamura, F; Kawase, I; Kijima, T; Komuta, K; Kumanogoh, A; Minami, S; Ogata, Y; Okafuji, K; Shiroyama, T; Tachibana, I; Yamamoto, S | 1 |
| Baek, JY; Cho, SH; Chung, IJ; Hong, YS; Jo, SJ; Kang, HJ; Kim, JH; Kim, KP; Kim, SY; Kim, TW; Lee, J; Lee, JW; Lee, KH; Lee, KW; Lim, HY; Park, YS; Shin, DB; Shin, SJ | 1 |
| Grothey, A | 1 |
| Adachi, T; Goto, A; Itoh, M; Kanno, S; Kondo, Y; Mitsuhashi, K; Shinomura, Y; Suzuki, T; Wakasugi, H; Yabana, T | 1 |
| Hirashima, Y; Shirao, K | 1 |
| Higashida, M; Hirai, T; Kubota, H; Matsumoto, H; Murakami, H; Nakamura, M; Nakashima, H; Oka, Y; Okumura, H; Tsutsumi, K | 1 |
| Baba, H; Baba, Y; Beppu, T; Chikamoto, A; Iwatsuki, M; Miyamoto, Y; Okabe, H; Sakamoto, Y; Watanabe, M | 1 |
| Beijnen, JH; Cats, A; Deenen, MJ; Mandigers, CM; Schellens, JH; Soesan, M; Terpstra, WE | 1 |
| Higashida, M; Hirai, T; Kawabe, Y; Kubota, H; Matsumoto, H; Murakami, H; Nakamura, M; Nakashima, H; Oka, Y; Okumura, H | 1 |
| Itami, J; Ito, Y; Kondo, S; Mayahara, H; Morizane, C; Morota, M; Murakami, N; Okusaka, T; Sumi, M; Ueno, H | 1 |
| Chu, Y; Ding, L; Liu, HY; Yu, Y; Zhu, H | 1 |
| Ba, Y; Deng, T; Guo, ZQ; Hu, CH; Huang, DZ; Meng, JC; Wan, HP; Wang, ML; Xiong, JP; Xu, N; Yan, Z; Yao, Y; Yu, Z; Yu, ZH; Zhang, Y; Zheng, RS; Zhuang, ZX | 2 |
| Chiba, T; Fukui, H; Maruo, T; Miwa, H; Okabe, Y; Osaki, Y; Oshima, T; Sekikawa, A; Tomita, T; Tsumura, T; Wakasa, T; Watari, J; Zhang, X | 1 |
| Asaishi, K; Goto, M; Higuchi, K; Kawabe, S; Kii, T; Kuwakado, S; Miyamoto, T; Nishitani, H; Yoshida, M | 1 |
| Morimoto, M; Nakagawa, M; Tangoku, A | 1 |
| Bian, HH; Chen, L; Pu, WY; Wang, H; Wang, J; Zhang, H; Zhu, H; Zhu, MG; Zhuang, ZX | 1 |
| Enomoto, K; Ito, M; Kurumatani, N; Matsumoto, S; Migita, K; Nakajima, Y; Saeki, K; Takayama, T; Tanaka, T; Wakatsuki, K | 1 |
| Saif, MW; Skoura, E; Syrigos, KN | 1 |
| Fuse, N; Hashizume, K; Ito, Y; Kato, K; Kiyota, N; Kuroki, Y; Minami, H; Ohtsu, A; Yamada, Y | 1 |
| Kobayashi, R; Nakagawa, K; Ohtomo, K; Okuma, K; Shiraishi, K; Yamashita, H | 1 |
| Ilson, DH | 1 |
| Benson, AB | 1 |
| Akizuki, S; Fushiya, N; Nishino, H; Ohnishi, A; Takagi, I | 1 |
| Chen, L; Chen, YX; Hao, LH; Jiang, XJ; Li, ZY; Lin, HZ; Song, MQ | 1 |
| Huang, XE; Qian, YD; Wang, L; Xiang, J; Xu, HQ; Xu, X | 1 |
| de Gramont, A; Green, E; Haller, DG; McCleary, NJ; Meyerhardt, JA; O'Connell, M; Saltz, LB; Sargent, DJ; Twelves, CJ; Van Cutsem, E; Yothers, G | 1 |
| Ishiguro, H; Takeuchi, M; Tanaka, S; Toi, M; Tsuji, W; Ueno, T | 1 |
| Ba, Y; Deng, T; Guo, Z; Hu, C; Huang, D; Meng, J; Wan, H; Wang, M; Xiong, J; Xu, N; Yan, Z; Yao, Y; Yu, Z; Zhang, Y; Zheng, R; Zhuang, Z | 1 |
| Ebata, T; Fukaya, M; Hirata, A; Igami, T; Itatsu, K; Nagino, M; Sugawara, G; Tsunoda, N; Uehara, K; Usui, H; Yokoyama, Y; Yoshioka, Y | 1 |
| Katayama, K; Nishino, T; Okitsu, H; Okitsu, N; Takahashi, Y; Tanaka, T | 1 |
| Fujiyama, Y; Kaneko, H; Kikuchi, M; Kinoshita, S; Nishizawa, T; Sakuno, T; Suzuki, H; Takahashi, M | 1 |
| Amagai, K; Boku, N; Denda, T; Fujita, Y; Hamamoto, Y; Kawai, H; Konishi, K; Mizusawa, J; Nakamura, K; Nishina, T; Nishisaki, H; Ohkawa, S; Ohtsu, A; Takashima, A; Tsuji, A; Tsuji, Y; Yamada, Y; Yamaguchi, K | 1 |
| Ajani, JA; Bodoky, G; Buyse, M; Carrato, A; Cascinu, S; Douillard, JY; Ferry, D; Gorbunova, V; Heinemann, V; Lichinitser, M; Moiseyenko, V; Zaucha, R | 1 |
| Atsumi, K; Hirata, H; Honda, H; Matsumoto, K; Nakamura, K; Nonoshita, T; Ooga, S; Sasaki, T; Shioyama, Y; Uehara, S; Yoshitake, T | 1 |
| Ahn, MS; Cho, YK; Choi, JH; Han, SU; Jeong, SH; Kang, SY; Lee, HW; Lee, KJ; Lee, SY; Lim, HY; Park, JS | 1 |
| Caudle, KE; Diasio, RB; Klein, TE; McLeod, HL; Schwab, M; Swen, JJ; Thorn, CF | 1 |
| Ando, M; Kadowaki, S; Komori, A; Kondo, C; Muro, K; Narita, Y; Nitta, S; Takahari, D; Taniguchi, H; Ura, T; Yamaguchi, K | 1 |
| Akiba, T; Enomoto, H; Kawahara, H; Toyama, Y; Watanabe, K; Yanaga, K | 1 |
| Boku, N; Fukuda, H; Kato, K; Mizusawa, J; Nakamura, K; Ohtsu, A; Shimada, Y; Shirao, K; Takashima, A | 1 |
| Hiro, J; Inoue, Y; Kawamoto, A; Kawamura, M; Kusunoki, M; Mohri, Y; Okugawa, Y; Saigusa, S; Tanaka, K; Toiyama, Y | 1 |
| Baba, H; Iwamoto, S; Komatsu, Y; Matsumoto, H; Mishima, H; Morita, S; Muro, K; Nakamura, M; Sakata, Y; Sasaki, Y; Satoh, T; Shimada, K; Shimada, Y; Sugihara, K; Takahari, D; Takahashi, K; Watanabe, M; Yamada, Y; Yoshida, K; Yoshida, M | 1 |
| Furuse, J | 1 |
| Chen, G; Li, J; Luo, X; Peng, L; Tan, C; Wan, X; Yi, L; Zeng, X; Zhao, Z | 1 |
| He, MM; Luo, HY; Qiu, MZ; Ren, C; Wang, F; Wang, FH; Wang, ZQ; Wu, WJ; Xu, RH; Zeng, ZL; Zhang, DS | 1 |
| Cao, C; Chen, J; Chen, Y; Gong, Y; Gu, D; Shen, Y; Tang, C; Zhang, Q; Zhang, X | 1 |
| Kanbara, Y; Tai, K; Terai, S | 1 |
| Akiba, T; Enomoto, H; Kawahara, H; Tomoda, M; Watanabe, K; Yanaga, K | 1 |
| Kanazawa, H; Matsumoto, N; Nagano, I; Niwa, M; Sato, T; Yamada, I; Yoshinaka, H | 1 |
| Hiraoka, N; Ikeda, M; Kondo, S; Mitsunaga, S; Morizane, C; Ohno, I; Okusaka, T; Shimizu, S; Shoji, H; Ueno, H | 1 |
| Cao, W; Cheng, C; Huo, BL; Wang, YH; Zhang, E | 1 |
| Chang, ZW; Dong, L; Han, ZF; Li, J; Lou, XP; Lu, P; Miao, JH | 1 |
| Chen, CC; Jiang, RS; Liang, KL; Lin, JC; Lin, PJ; Liu, YC; Shih, YT; Twu, CW; Wang, WY; Wu, CT | 1 |
| Hasegawa, Y; Hatanaka, M; Iwata, H | 1 |
| Fushimi, K; Takami, M; Tanabe, N | 1 |
| Bang, YJ; Chie, EK; Ha, SW; Han, SW; Im, SA; Jang, JY; Kim, K; Kim, SW; Kim, TY; Oh, DY | 1 |
| An, HX; Li, DH; Pan, ZK; Wu, JX; Ye, F | 1 |
| Hara, K; Ishii, T; Kondo, H; Koyama, I; Morita, Y; Suzuki, A; Tashiro, J; Yamaguchi, S | 1 |
| Sakamoto, K; Sakashita, K; Sawada, R; Sunami, T; Tauchi, J; Yukimoto, K | 1 |
| Konno, F; Matsumoto, H; Mitsui, K; Namiki, K; Takahashi, T; Yoshida, R | 1 |
| Ema, A; Naito, M; Nakamura, T; Sato, T; Watanabe, M; Yamashita, K | 1 |
| Akaike, M; Fukuda, H; Hamaguchi, T; Kanemitsu, Y; Kato, T; Kubo, Y; Mishima, H; Mizusawa, J; Moriya, Y; Nakamura, K; Ohue, M; Saito, N; Sato, T; Shimada, Y; Takiguchi, N; Takii, Y; Tomita, N; Yamaguchi, S | 1 |
| Castro-Rojas, C; Ortiz-Lópezj, R; Rojas-Martínez, A | 1 |
| Cao, C; Chen, J; Gu, D; He, M; Kuang, M; Tang, C; Zhang, X | 1 |
| Alvarez, E; Calvo, FA; Del Valle, E; Deutsch, E; Garcia-Alfonso, P; García-Sabrido, JL; Muñoz-Calero, A; Peligros, I; Rivera, S; Rodriguez, M; Serrano, J; Sole, CV; Turégano, F | 1 |
| Chiba, M; Ishii, Y; Yamada, H; Yamamiya, I; Yoshisue, K | 1 |
| Guo, H; Jin, M; Li, J; Liu, X; Lv, F; Shen, L; Wang, B | 2 |
| Fang, W; Jiang, H; Mao, C; Qian, J; Xu, N; Zhang, X; Zhao, P; Zheng, Y | 1 |
| Hong, YS; Jeon, EK; Kim, HK; Ko, YH; Park, JC; Park, SY; Shim, BY; Sun, DS; Won, HS | 1 |
| Baba, H; Boku, N; Denda, T; Esaki, T; Hyodo, I; Ina, K; Komatsu, Y; Kuwano, H; Morita, S; Muro, K; Nishina, T; Sameshima, S; Satoh, T; Shimada, Y; Sugihara, K; Tokunaga, S; Tsuji, A; Watanabe, M; Yamaguchi, K; Yasui, H | 1 |
| Ishii, Y; Yamada, H; Yamamiya, I; Yoshida, K; Yoshisue, K | 1 |
| Hasegawa, H; Ishii, Y; Kitagawa, Y; Okabayashi, K; Shigeta, K | 1 |
| Aoe, K; Fujiwara, K; Gemba, K; Harita, S; Hosokawa, S; Hotta, K; Kanazawa, S; Kato, Y; Katsui, K; Kishino, D; Kiura, K; Kozuki, T; Kubo, T; Maeda, T; Nogami, N; Okada, T; Tabata, M; Takigawa, N; Tanimoto, M; Ueoka, H; Yasugi, M | 1 |
| Lin, RF; Luo, WH; Su, M; Wei, HP; Zhu, LC; Zou, CL | 1 |
| Ahn, JB; Bello, M; Charoentum, C; Chen, LT; Cheng, AL; Ciardiello, F; de Lima Lopes, G; Ho, GF; Kim, TW; Köhne, CH; Kong, HL; Lam, KO; Li, J; Liu, TS; Ma, BB; Park, YS; Shaw, M; Sriuranpong, V; Sudoyo, AW; Teh, C; Vaid, AK; Wang, JY; Zhang, J; Zhang, SZ | 1 |
| Hara, Y; Minami, Y; Nakamura, T; Ueda, S | 1 |
| Bae, JM; Choi, MG; Kang, WK; Kim, S; Lee, J; Lee, JH; Lee, SJ; Lim, DH; Lim, HY; Park, JO; Park, SH; Park, YS; Sohn, TS | 1 |
| Endo, K; Kita, M; Kondo, S; Muramatsu, M; Murono, S; Tsuji, A; Wakisaka, N; Yoshida, S; Yoshizaki, T | 1 |
| Baek, JY; Cho, SH; Chung, IJ; Hong, YS; Jo, SJ; Kang, HJ; Kim, JH; Kim, KP; Kim, ST; Kim, SY; Kim, TW; Lee, J; Lee, JW; Lee, KH; Lee, KW; Lim, HY; Park, YS; Shin, DB; Shin, SJ | 1 |
| Chen, X; Gao, P; Liu, H; Lu, X; Song, Y; Sun, J; Wang, Z; Xu, H; Zhang, N | 1 |
| Hanazaki, K; Kitagawa, H; Kobayashi, M; Maeda, H; Munekage, E; Namikawa, T | 1 |
| Cai, J; Li, T; Wu, B; Xu, Y; Zhao, G | 1 |
| Igishi, T; Izumi, H; Kodani, M; Kurai, J; Makino, H; Matsumoto, S; Nakazaki, H; Nirodi, CS; Nishii-Ito, S; Sakamoto, T; Shimizu, E; Takata, M; Takeda, K; Tanaka, N; Touge, H; Ueda, Y; Yanai, M | 1 |
| Boku, N; Denda, T; Esaki, T; Hyodo, I; Kato, T; Kuwano, H; Nishina, T; Ohishi, T; Ojima, H; Otsuji, T; Shimada, K; Shirao, K; Takeuchi, M; Yamazaki, K | 1 |
| Chen, L; Feng, D; Leong, M; Li, T | 1 |
| Magdy, T; Nies, AT; Schwab, M; Zanger, UM | 1 |
| Haneda, S; Kajiwara, T; Kohyama, A; Komura, T; Kudoh, K; Miura, K; Musha, H; Naitoh, T; Ohnuma, S; Shimada, M; Shirasaka, T; Toshima, M; Unno, M | 1 |
| Ajani, JA; Bodoky, G; Carrato, A; Cascinu, S; Jassem, J; Moiseyenko, V; Prausová, J; Rivera, F; Scheulen, ME; Van Laethem, JL; Vynnychenko, I | 1 |
| Hishida, T; Kunitoh, H; Ohashi, Y; Sakurai, H; Shukuya, T; Takamochi, K; Tsuboi, M; Yoh, K | 1 |
| Egawa, T; Ito, Y; Kemmochi, T; Mihara, K; Nagashima, A; Nishiya, S; Yamashiro, N | 1 |
| Doki, Y; Kurokawa, Y; Miyata, H; Miyazaki, Y; Mori, M; Nakajima, K; Takahashi, T; Takiguchi, S; Yamasaki, M | 1 |
| Ariyoshi, K; Iwase, S; Kawaguchi, T; Kitamura, K; Miyaji, T; Nagumo, Y; Odagiri, H; Sueoka, N; Teramoto, S; Tsubota, Y; Yamaguchi, T; Yamamoto, C; Yamamoto, D | 1 |
| Chen, MW; Huang, HQ; Huang, JJ; Jiang, DK; Lu, DC; Wu, FL; Yang, X; Ying, YP; Zeng, HY; Zhou, AM; Zhou, J | 1 |
| Furuya, T; Hayashi, H; Murakami, T; Shimokawa, Y; Sugihara, S; Yahara, N; Yanai, H | 1 |
| Korytov, OV; Korytova, LI; Krasnikoval, VG; Meshechkin, AV; Sandalevskaya, AG | 1 |
| Bi, F; Cao, D; Chen, Y; Gou, HF; Li, Q; Li, ZP; Liu, JY; Peng, XC; Qiu, M; Shen, YL; Wang, X; Xu, F; Yang, Y; Yi, C; Zhao, YQ | 1 |
| Beeker, A; Erdkamp, F; Erjavec, Z; Gelderblom, H; Kapiteijn, E; Kroep, JR; Nortier, HW; Polee, M; Stiggelbout, AM; van Bochove, A; van Groeningen, CJ; van Werkhoven, E; Weijl, N | 1 |
| Hasegawa, Y; Nitta, H; Sasaki, A; Takahara, T; Umemura, A; Wakabayashi, G | 1 |
| Goto, A; Ichikawa, Y; Iwasa, S; Kato, K; Matsumoto, H; Nagashima, K; Okita, NT; Shimada, Y; Yamada, Y; Yamaguchi, T; Yasui, H | 1 |
| Skoropad, VY | 1 |
| Carrato, C; Luquin, N; Sierra, S | 1 |
| Boku, N; Booka, E; Gomi, D; Hamamoto, Y; Ichiyama, T; Imamura, CK; Kawakubo, H; Kitagawa, Y; Mizukami, T; Soejima, K; Takahashi, T; Takeuchi, H; Tanigawara, Y; Tateishi, K | 1 |
| Ohi, H; Ozaki, T; Seki, H; Yabusaki, H | 1 |
| Gamoh, M; Goto, R; Ishioka, C; Komatsu, Y; Kurihara, M; Morita, S; Sato, A; Shimada, K; Takahashi, S; Yamada, Y; Yamaguchi, T; Yuki, S | 1 |
| Chang, PY; Chen, JH; Chen, YG; Ho, CL; Lu, CS; Wu, YY | 1 |
| Chin, K; Fujii, M; Inada, T; Kitagawa, Y; Kodera, Y; Lee, SW; Nakajima, T; Nashimoto, A; Nomura, E; Ohyama, S; Omura, K; Sakata, Y; Sakuramoto, S; Takeuchi, M; Tanigawa, N; Terashima, M; Yamaguchi, T; Yamaue, H | 1 |
| Amagai, K; Boku, N; Gotoh, M; Hamamoto, Y; Kawai, H; Mizusawa, J; Nakamura, K; Nakayama, N; Nishina, T; Ohtsu, A; Shimada, Y; Shirao, K; Yamaguchi, K; Yasui, H | 1 |
| Cheng, Y; Guan, ZG; Guo, ZQ; Hu, XH; Li, W; Li, YH; Liu, YP; Lu, HS; Qiu, MZ; Sun, GP; Wang, JJ; Xu, JM; Xu, RH; Yu, SY; Zhang, HL; Zhong, MZ; Zhou, JT | 1 |
| Abdel-Rahman, O; ElHalawani, H; Essam-Eldin, S | 1 |
| Ahn, JB; Baik, SH; Hong, SP; Hur, H; Jung, I; Jung, M; Keum, KC; Kim, H; Kim, NK; Kim, TI; Koom, WS; Lim, JS; Min, BS; Park, YS; Roh, JK; Shin, SJ | 1 |
| Deng, Y; Ding, H; Ding, Y; Fan, H; Hu, Y; Lai, W; Peng, M; Tao, G; Wu, X; Wu, Y; Yu, L; Zhang, H | 1 |
| Amstutz, U; Beijnen, JH; Cats, A; Deenen, MJ; Froehlich, TK; Gross, E; Henricks, LM; Jennings, BA; Kleibl, Z; Kleiblova, P; Koopman, M; Largiadèr, CR; Marinaki, AM; Meulendijks, D; Palles, C; Punt, CJ; Sanderson, JD; Schellens, JH; Schwab, M; Sonke, GS; Tomlinson, I; van Kuilenburg, AB; Zanger, UM | 1 |
| Ashida, R; Ioka, T; Katayama, K; Sakon, M; Takahashi, H; Teshima, T | 1 |
| Haga, A; Kiritoshi, T; Nakagawa, K; Ohtomo, K; Okuma, K; Takenaka, R; Yamashita, H | 1 |
| Cho, BC; Choi, EC; Kim, HR; Kim, JH; Koh, YW; Lee, CG | 1 |
| Wang, D; Wang, X; Yu, X | 1 |
| Endo, T; Hasegawa, H; Ishii, Y; Kitagawa, Y; Kondo, T; Ochiai, H; Okabayashi, K; Shigeta, K; Tsuruta, M | 1 |
| Amada, E; Baba, S; Kameyama, N; Mitsuhashi, H; Miyata, R; Tomita, M | 1 |
| Hashimoto, K; Kogo, R; Nakagawa, T; Nakano, T; Nakashima, T; Sato, M; Sawatsubashi, M; Yasumatsu, R | 1 |
| Liu, J; Ma, S; Zhu, L | 1 |
| Chen, M; Chen, XD; He, FQ; Tang, LC; Tang, XL | 1 |
| Hata, K; Ishihara, S; Kawai, K; Kiyomatsu, T; Murono, K; Nishikawa, T; Nozawa, H; Otani, K; Tanaka, T; Watanabe, T; Yasuda, K | 1 |
| Abe, N; Fujinaga, A; Hayashi, H; Hirata, K; Ito, K; Komatsu, Y; Matsuda, K; Uchida, T | 1 |
| Kurono, Y; Matushita, K; Nagano, H | 1 |
| Anderegg, MC; Haj Mohammad, N; Mali, RMA; Ngai, LL; Ter Veer, E; van Laarhoven, HWM; van Oijen, MGH; van Valkenhoef, G | 1 |
| Hoya, Y; Mitsumori, N; Nakayoshi, T; Okamoto, T; Sekine, H; Taki, T; Watanabe, A; Yanaga, K | 1 |
| Kaiho, T; Kobayashi, S; Koda, K; Kosugi, C; Maruyama, T; Matsubara, H; Miyauchi, H; Takiguchi, N | 1 |
| Dai, X; Jiang, J; Wang, C; Wu, C; Zhang, X | 1 |
| Chen, DL; Guo, P; Hao, YT; He, MM; He, YY; Jin, Y; Li, YH; Luo, HY; Qiu, MZ; Ren, C; Wang, DS; Wang, F; Wang, FH; Wang, ZQ; Wang, ZX; Xu, RH; Yuan, SQ; Zeng, YX; Zeng, ZL; Zhang, DS | 1 |
| Chen, Z; Guo, W; Huang, M; Li, J; Li, W; Liu, X; Qiu, L; Wang, H; Zhang, W; Zhao, X; Zhu, X | 1 |
| Kadowaki, S; Muro, K; Narita, Y; Sugiyama, K; Tajika, M; Ura, T | 1 |
| Ci-Ren, BS; Duo-Ji, MM; Long, ZW; Luo, DL; Zhang, XH | 1 |
| Kong, L; Kou, P; Shao, W; Wang, H; Yu, J; Zhang, J; Zhang, Y; Zhu, H | 1 |
| Kaito, A; Kinoshita, T; Nishida, T; Shibasaki, H; Shitara, K | 1 |
| Fukayama, M; Hata, K; Ishihara, S; Kawai, K; Kiyomatsu, T; Morikawa, T; Nozawa, H; Watanabe, T | 1 |
| Hu, S; Jiang, Y; Sun, Y; Xue, L; Xue, X; Yang, L; Yue, J; Zhu, Y | 1 |
| Chen, JH; Ho, CL; Hsiao, CW; Huang, WY; Jao, SW; Lee, CC; Lo, CH; Wu, CC; Yang, JF | 1 |
| Hanafusa, T; Hashimoto, T; Matsuda, K; Namiki, T; Ueno, M; Yokozeki, H | 1 |
| Fang, M; Jia, Y; Li, J; Liang, X; Luo, L; Lv, S; Song, T; Xu, H | 1 |
| Miyakita, H; Nagase, H; Ogimi, T; Okada, K; Sadahiro, S; Saito, G; Suzuki, T; Tanaka, A | 1 |
| Franck, C; Malfertheiner, P; Venerito, M | 1 |
| Hashimoto, Y; Hirata, Y; Ishizaki, Y; Kitamura, S; Kuga, Y; Miwata, T; Mouri, T | 1 |
| Doki, Y; Fujita, J; Fujitani, K; Fujiwara, Y; Hirao, M; Imamura, H; Kimura, Y; Moon, JH; Mori, M; Takiguchi, S; Tamura, S; Yano, M | 1 |
| Broto, M; Galve, R; Marco, MP; McCabe, R | 1 |
| Akashi, K; Arita, S; Ariyama, H; Baba, E; Esaki, T; Inadomi, K; Kusaba, H; Makiyama, A; Makiyama, C; Mitsugi, K; Shibata, Y; Shinohara, Y; Shirakawa, T; Takayoshi, K; Tsuchihashi, K; Uchino, K; Uenomachi, M | 1 |
| Asada, H; Miyagawa, F; Sho, M; Sugano, Y | 1 |
| Chionh, F; Lau, D; Price, T; Tebbutt, N; Yeung, Y | 1 |
| Anderegg, MCJ; Mohammad, NH; Ngai, LL; Ter Veer, E; Valkenhoef, GV; van Laarhoven, HWM; van Oijen, MGH | 1 |
| Bulitta, JB; Jeong, SW; Kim, TH; Kwon, DR; Min, BS; Park, GY; Shin, BS; Shin, JC; Shin, S; Weon, KY; Woo, MH; Yoo, SD | 1 |
| Abdalla, K; Abramov, M; Ajani, JA; Alsina, M; Aoyama, T; Benedetti, F; Bondarenko, I; Elme, A; Esko, V; Feliu, J; Gorbunova, V; Hontsa, A; Lazarev, S; Makris, L; Mizuguchi, H; Otchenash, N; Rosati, G; Shparyk, Y; Verma, U | 1 |
| Kazaoka, Y; Nishio-Nagai, M; Suzuki, S; Ueda, R; Yoshikawa, K | 1 |
| Fukuda, T; Hagiwara, Y; Kawahara, T; Mukai, H; Ohashi, Y; Shimozuma, K; Shiroiwa, T; Taira, N; Uemura, Y; Watanabe, T | 1 |
| Furuta, R; Ina, K | 1 |
| Denda, T; Gamoh, M; Ishioka, C; Iwanaga, I; Kobayashi, K; Kobayashi, Y; Komatsu, Y; Kotake, M; Miyamoto, Y; Morita, S; Nakamura, M; Ohori, H; Sato, A; Shimada, K; Shimodaira, H; Takahashi, S; Tsuda, M; Yamada, Y; Yamaguchi, T; Yuki, S | 1 |
| Chang, JS; Chung, SY; Lee, BM; Lee, KJ; Seong, J | 1 |
| Chae, H; Kim, HI; Kim, IH; Kim, MC; Kwon, IK; Lee, CM; Lee, HH; Lee, SI; Min, JS; Park, SS | 1 |
| Baba, T; Ebata, T; Kokuryo, T; Nagino, M; Uehara, K; Yamaguchi, J; Yokoyama, Y | 1 |
| An, JY; Kim, S; Kim, SM; Lee, J; Sohn, TS | 1 |
| Abe, K; Gocho, T; Haruki, K; Onda, S; Sakamoto, T; Takano, Y; Uwagawa, T; Yanaga, K | 1 |
| Ahmad, R; Cao, Y; Du, F; Jiang, J; Ma, X; Ren, D; Shen, G; Wang, Z; Zhang, H; Zhang, S; Zhao, F; Zhao, J; Zheng, F | 1 |
| Cai, Z; Chen, Z; Shen, C; Wang, J; Yin, X; Yin, Y; Zhang, B; Zhou, Y | 1 |
| Huang, KW; Kim, MD; Li, SP; Liang, PC; Pua, U; Qiu, YD; Song, TQ; Yang, PC | 1 |
| Akune, Y; Shigeyasu, C; Yamada, M | 1 |
| Huang, C; Huang, Y; Huang, Z; Wu, B; Xu, Z; Yin, Y; Zhang, J; Zhuang, W | 1 |
| Cheng, X; Cui, YH; Hou, J; Ji, Y; Liu, FL; Liu, TS; Shen, ZB; Sun, YH; Wang, Y | 1 |
| Araki, T; Fujikawa, H; Hiro, J; Ide, S; Kusunoki, M; Ohi, M; Okugawa, Y; Saigusa, S; Toiyama, Y; Yamamoto, A; Yasuda, H; Yoshiyama, S | 1 |
| Aoyama, T; Asahara, T; Hirata, K; Kusano, M; Nakamori, S; Oba, K; Ohashi, Y; Okabayashi, K; Saji, S; Sakamoto, J; Tsuji, Y; Yoshikawa, T | 1 |
| Cui, S; Sun, Y; Ye, M; You, D; Zhao, Q | 1 |
| Hsu, TC; Wang, CC | 1 |
| Baba, H; Beppu, T; Chikamoto, A; Fukubayashi, K; Hayashi, H; Imai, K; Imamura, YU; Ishiko, T; Miyata, T; Yamashita, YI | 1 |
| Milano, G | 1 |
| Fukutomi, A; Kasai, J; Kashiwagi, H; Kawahira, M; Kawakami, T; Machida, N; Mori, K; Omae, K; Tsushima, T; Yamaguchi, K; Yasui, H; Yoshisue, K | 1 |
| Chang, X; Chen, J; Deng, L; Ge, X; Han, C; Li, C; Liang, J; Lin, Y; Ni, W; Pang, Q; Sun, X; Wang, L; Wang, P; Wang, W; Wang, X; Xiao, Z; Zhang, W; Zhao, Y; Zhou, Z | 1 |
| Boku, N; Hirano, H; Honma, Y; Ito, T; Iwasa, S; Kato, K; Okita, N; Shoji, H; Takashima, A | 1 |
| Ariake, K; Hata, T; Hayashi, H; Kamei, T; Mitachi, K; Mizuma, M; Motoi, F; Naitoh, T; Nakagawa, K; Ohtsuka, H; Unno, M | 1 |
| Arai, H; Boku, N; Fukuda, N; Hironaka, S; Iwasa, S; Kawahira, M; Masuishi, T; Minashi, K; Muro, K; Nakajima, TE; Takahari, D; Yasui, H | 1 |
| Bae, WK; Cho, SH; Chung, IJ; Hwang, EC; Hwang, JE; Jeong, O; Kim, H; Park, YK; Ryu, SY; Shim, HJ | 1 |
| Hirai, A; Ichiki, Y; Imanishi, N; Ishida, T; Kusanagi, K; Shinohara, S; Takeda, Y; Tanaka, F; Tashima, Y; Yoshimatsu, K | 1 |
| Fujishiro, M; Fujita, KI; Hasegawa, C; Ikeda, K; Ishida, H; Iwabuchi, S; Kumazawa, T; Lee, XP; Matsuyama, T; Onda, H; Sakamaki, H; Sasaki, Y; Sato, K; Shiokawa, R; Yamada, M | 1 |
| Cruz-Muñoz, W; Hileeto, D; Kerbel, RS; Man, S; Muñoz, R; Viloria-Petit, A; Wood, GA; Xu, P | 1 |
| Cho, K; Cho, S; Gwon, MR; Kang, WY; Kim, BK; Kim, JG; Lee, HW; Ohk, B; Seong, SJ; Sung, YK; Yoon, YR | 1 |
| Hata, T; Ito, S; Ito, Y; Kaneda, N; Kuriki, R; Misawa, K; Nakayama, K; Tatematsu, M | 1 |
| Akashi, K; Ariyama, H; Baba, E; Isobe, T; Ito, M; Komoda, M; Kusaba, H; Kuwayama, M; Momosaki, S; Nakano, M; Oda, Y; Ohmura, H; Okada, C; Okumura, Y; Tanishima, S; Tsuchihashi, K; Uchino, K; Yamada, Y; Yamaguchi, K | 1 |
| Marsch, AF; Shakhbazova, A | 1 |
| Arita, T; Fujiwara, H; Imamura, T; Kishimoto, T; Kiuchi, J; Komatsu, S; Konishi, H; Kosuga, T; Kubota, T; Nishibeppu, K; Okamoto, K; Otsuji, E; Shiozaki, A | 1 |
| Doi, S; Fujiwara, H; Kawamura, T; Mikami, R; Nakamoto, Y; Noda, M; Okumoto, T; Tokunaga, Y; Tomita, N | 1 |
| Endo, I; Kumamoto, T; Matsuyama, R; Murakami, T; Sawada, Y; Tsuchiya, N; Yabushita, Y | 1 |
| Ito, Y; Kobuchi, S; Matsumura, E; Sakaeda, T | 1 |
| Huang, H; Jin, H; Lou, Q; Shah, RJ; Wang, J; Wang, Y; Yang, J; Zhang, X; Zhou, H | 1 |
| Chan, LF; Kamei, Y; Miyakita, H; Ogimi, T; Okada, K; Sadahiro, S; Saito, G; Suzuki, T | 1 |
| Ando, M; Kadowaki, S; Komori, A; Masuishi, T; Mitani, S; Muro, K; Narita, Y; Taniguchi, H; Ura, T | 1 |
| Chen, X; Ding, H; Ding, J; Luo, D; Wang, L; Wei, Y; Xiong, Y; Yi, F; Zhang, W | 1 |
| Hattori, N; Hayashi, M; Iwata, N; Kanda, M; Kodera, Y; Koike, M; Nakayama, G; Omae, K; Shimizu, D; Tanaka, C; Yamada, S | 1 |
| Arnold, D; Blohmer, JU; Bokemeyer, C; Borner, M; Brucker, S; Burmeister, T; Cascorbi, I; de Wit, M; Decker, T; Dietz, A; Einsele, H; Eisterer, W; Folprecht, G; Hilbe, W; Hoffmann, J; Hofheinz, RD; Knauf, W; Köhne, CH; Kunzmann, V; Largiadèr, CR; Lorenzen, S; Lüftner, D; Moehler, M; Nöthen, MM; Pox, C; Reinacher-Schick, A; Scharl, A; Schlegelberger, B; Schwab, M; Seufferlein, T; Sinn, M; Stroth, M; Tamm, I; Trümper, L; Wilhelm, M; Wöll, E; Wörmann, B | 1 |
| Cui, H; Dai, G; Deng, G; Guan, J; Lou, C; Yuan, J; Zhang, W; Zhang, Y; Zhou, A; Zhou, J | 1 |
| Akiyama, F; Inaji, H; Kurosumi, M; Masuda, N; Ohashi, Y; Ohno, S; Ohsumi, S; Saji, S; Sato, N; Shimomura, A; Takao, S; Tokuda, Y; Tsuda, H; Watanabe, T | 1 |
| Aoki, Y; Boku, N; Booka, E; Funakoshi, T; Hamamoto, Y; Imamura, CK; Kawakami, T; Kawakubo, H; Kitagawa, Y; Kitago, M; Mizukami, T; Takeuchi, H; Takeuchi, M; Tanigawara, Y; Wakuda, K | 1 |
| Akagi, Y; Ando, K; Baba, H; Enomoto, M; Fujita, F; Ihara, K; Miwa, K; Mori, M; Mori, S; Nakayama, G; Oki, E; Saeki, H; Shimokawa, M; Tominaga, M | 1 |
| Bm Claes, K; Borbath, I; Casneuf, V; Demey, W; Geboes, KP; Haufroid, V; Van den Eynde, M; Verheezen, Y; Verstraete, AG | 1 |
| Endo, Y; Hirashita, T; Inomata, M; Itoh, H; Iwao, M; Iwashita, Y; Masuda, T; Shiraiwa, K; Suzuki, Y; Tada, K; Tanaka, R; Uchida, H | 1 |
| Chang, PY; Chen, JH; Chen, PH; Chen, YC; Chen, YG; Chien, WC; Chung, CH; Dai, MS; Ho, CL; Hu, JM; Huang, TC; Lai, SW; Lee, CH; Wu, YY; Yang, SS; Yeh, RH | 1 |
| Baba, H; Denda, T; Gamoh, M; Ishioka, C; Iwanaga, I; Kobayashi, Y; Komatsu, Y; Kotake, M; Morita, S; Nakamura, M; Ohori, H; Sakashita, A; Sato, A; Shimada, K; Takahashi, M; Takahashi, S; Takashima, A; Tsuda, M; Yamada, Y; Yamaguchi, T; Yuki, S | 1 |
| Hara, K; Ide, M; Kuriyama, K; Nakazawa, N; Ogawa, H; Oyama, T; Saeki, H; Sakai, M; Sano, A; Shimoda, Y; Shirabe, K; Sohda, M; Ubukata, Y; Yokobori, T | 1 |
| Agarwal, R; Grieb, BC | 1 |
| Ishizawa, K; Mitsuboshi, S; Niimura, T; Sakamoto, Y; Yoshino, M; Zamami, Y | 1 |
| Ye, Y; Zheng, S | 1 |
| Abdelmoneim, M; Bustos-Villalobos, I; Ichinose, T; Kasuya, H; Kikumori, T; Kodera, Y; Matsumura, S; Miyajima, N; Morimoto, D; Mukoyama, N; Naoe, Y; Ragab Eissa, I; Shibata, M; Takeuchi, D; Tanaka, M; Tsunoda, N | 1 |
| Akazawa, M; Narimatsu, H; Sasahara, Y; Takumoto, Y | 1 |
| Arakawa, A; Ii, Y; Irie, T; Kawaguchi, M; Kawai, M; Kobari, A; Kojima, Y; Momose, H; Sakamoto, K; Sugimoto, K; Terao, Y; Tomiki, Y; Tsukamoto, R | 1 |
| Ito, Y; Kobuchi, S; Nakamura, T; Okamura, M; Tsuda, M | 1 |
| Abe, S; Emoto, S; Ishihara, S; Kawai, K; Matsuzaki, H; Murono, K; Nagai, Y; Nozawa, H; Oba, K; Sasaki, K; Shinagawa, T; Sonoda, H; Yamamoto, Y; Yokoyama, Y; Yoshioka, Y | 1 |
| Agatsuma, N; Imamaki, H; Nishikawa, Y; Oguro, F; Oura, M | 1 |
179 review(s) available for fluorouracil and tegafur
| Article | Year |
|---|---|
[Chemotherapy of gastrointestinal tumors (review of the literature)].
Topics: Ancitabine; Carcinoma, Hepatocellular; Colonic Neoplasms; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Humans; Immunotherapy; Intestinal Neoplasms; Intestine, Small; Liver Neoplasms; Mitomycins; Neoplasm Metastasis; Nitrosourea Compounds; Palliative Care; Pancreatic Neoplasms; Porfiromycin; Remission, Spontaneous; Stomach Neoplasms; Streptozocin; Tegafur | 1978 |
A recent overview of chemotherapy for advanced stomach cancer in Japan.
Topics: Antineoplastic Agents; Carbazilquinone; Chromomycins; Drug Therapy, Combination; Fluorouracil; Humans; Immunotherapy; Infusions, Intra-Arterial; Japan; Mitomycins; Neoplasm Metastasis; Prognosis; Stomach Neoplasms; Tegafur | 1978 |
[Drug treatment of inoperable stomach cancer].
Topics: Administration, Oral; Drug Administration Schedule; Drug Evaluation; Fluorouracil; Humans; Injections, Intravenous; Stomach Neoplasms; Tegafur | 1976 |
[Dose intensity in cancer chemotherapy in gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Humans; Methotrexate; Mitomycin; Mitomycins; Stomach Neoplasms; Suppositories; Tegafur | 1990 |
[Chemotherapy of tumors of the gastrointestinal tract].
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Digestive System Neoplasms; Doxorubicin; Fluorouracil; Humans; Lomustine; Mitomycin; Mitomycins; Tegafur | 1985 |
Potentiation of antimetabolite action by alkylating agents.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Doxorubicin; Drug Synergism; Female; Fluorouracil; Humans; Mitomycin; Mitomycins; Nitrosourea Compounds; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms; Tegafur | 1985 |
The pharmacology of prodrugs of 5-fluorouracil and 1-beta-D-arabinofuranosylcytosine.
Topics: Acylation; Ancitabine; Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Cytarabine; Floxuridine; Fluorouracil; Humans; Phospholipids; Pyrimidines; Steroids; Tegafur | 1984 |
[The diffuse endocrine system and the carcinoids of the alimentary tract. Part I: Orthological aspects and common morphological features of the carcinoids (author's transl)].
Topics: Adrenocorticotropic Hormone; Aged; Appendiceal Neoplasms; APUD Cells; Carcinoid Tumor; Carmustine; Cytoplasmic Granules; Digestive System; Doxorubicin; Endocrine Glands; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Ileal Neoplasms; Intestinal Polyps; Jejunal Neoplasms; Male; Middle Aged; Multiple Endocrine Neoplasia; Precancerous Conditions; Tegafur | 1982 |
Effect of human renal and hepatic disease on the pharmacokinetics of anticancer drugs.
Topics: Antineoplastic Agents; Aspartic Acid; Bleomycin; Cisplatin; Cyclophosphamide; Doxorubicin; Fluorouracil; Gallium; Humans; Kidney Diseases; Kinetics; Liver Diseases; Metabolic Clearance Rate; Methotrexate; Phosphonoacetic Acid; Protein Binding; Tegafur | 1982 |
Chemotherapy in alimentary tract malignomas.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carmustine; Colonic Neoplasms; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lomustine; Male; Methotrexate; Mitomycin; Mitomycins; Rectal Neoplasms; Semustine; Stomach Neoplasms; Streptozocin; Tegafur; Vincristine | 1981 |
Treatment of cultured human colon carcinoma cells with fluorinated pyrimidines.
Topics: Cell Line; Cell Survival; Colonic Neoplasms; Culture Media; Drug Evaluation, Preclinical; Fluorouracil; Humans; Tegafur; Thymidine; Uridine | 1980 |
[Chemotherapy of stomach cancer].
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Biological Availability; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Humans; Mitomycins; Nitrosourea Compounds; Stomach Neoplasms; Tegafur; Time Factors | 1980 |
The pharmacology of ftorafur (R, S-1-(tetrahydro-2-furanyl)-5-fluorouracil.
Topics: Animals; Biotransformation; Fluorouracil; Humans; Kinetics; Neoplasms; Tegafur | 1981 |
Studies of analogs of fluorinated pyrimidine in Japan.
Topics: Animals; Antineoplastic Agents; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fluorouracil; Humans; Japan; Neoplasms; Neoplasms, Experimental; Tegafur; Uracil | 1981 |
[Metabolic modulation as a method in tumor chemotherapy].
Topics: Antineoplastic Agents; Cytarabine; Fluorouracil; Humans; Methotrexate; Neoplasms; Tegafur; Thymidine; Uracil | 1982 |
[Combined chemotherapy with 5-FU+cis-platin or UFT+cisplatin].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Colorectal Neoplasms; Drug Administration Routes; Drug Administration Schedule; Fluorouracil; Humans; Stomach Neoplasms; Tegafur; Uracil | 1995 |
[Chemotherapy of scirrhous gastric cancer].
Topics: Adenocarcinoma, Scirrhous; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Etoposide; Fluorouracil; Humans; Interferon alpha-2; Interferon-alpha; Leucovorin; Levoleucovorin; Mitomycin; Nimustine; Recombinant Proteins; Stomach Neoplasms; Tegafur; Uracil | 1994 |
[Overview of clinical trials on adjuvant chemotherapy for curatively resected gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Cytarabine; Fluorouracil; Gastrectomy; Humans; Mitomycin; Stomach Neoplasms; Tegafur | 1994 |
[Development of fluorinated pyrimidines in Japan].
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Deoxycytidine; Drug Combinations; Fluorodeoxyuridylate; Fluorouracil; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasms; Neoplasms, Experimental; Oxonic Acid; Pyridines; Rats; Tegafur | 1993 |
New anticancer agents in clinical development.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Deoxycytidine; Enzyme Inhibitors; Fluorouracil; Gemcitabine; Humans; Neoplasms; Polysaccharides, Bacterial; Prodrugs; Quinazolines; Tegafur; Thiophenes; Thymidylate Synthase; Uracil | 1995 |
Intraarterial infusion chemotherapy for unresectable hepatic metastases from colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Liver Neoplasms; Mitomycin; Survival Rate; Tegafur; Uracil | 1996 |
Primary linitis plastica of the rectum: report of four cases and review of the literature.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Humans; Linitis Plastica; Male; Middle Aged; Mitomycins; Prognosis; Rectal Neoplasms; Tegafur; Time Factors; Uracil | 1996 |
[Clinical use of platinum compounds and fluorinated pyrimidines for lung cancer].
Topics: Antineoplastic Agents; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Drug Combinations; Fluorouracil; Humans; Lung Neoplasms; Tegafur; Uracil | 1996 |
Modulation of 5-FU and its related compounds.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Fluorouracil; Humans; Neoplasms; Pyridines; Tegafur; Uracil | 1997 |
[Benefits of adjuvant chemotherapy for breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Drug Combinations; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Mitomycin; Randomized Controlled Trials as Topic; Tamoxifen; Tegafur; Uracil | 1997 |
Current and future directions in adjuvant combined-modality therapy of rectal cancer.
Topics: Antidotes; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Combinations; Fluorouracil; Forecasting; Humans; Leucovorin; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Rectal Neoplasms; Tegafur; Uracil | 1997 |
[Chemoradiation for rectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Autonomic Pathways; Drug Administration Schedule; Fluorouracil; Humans; Nimustine; Radiotherapy Dosage; Rectal Neoplasms; Rectum; Tegafur | 1997 |
[Invention of a tumor-selective 5-fluorouracil derivative named S-1 by biochemical modulation of 5-fluorouracil].
Topics: Animals; Anorexia; Antimetabolites, Antineoplastic; Diarrhea; Dogs; Drug Combinations; Female; Fluorouracil; Immunologic Factors; Male; Mice; Mice, Nude; Oxonic Acid; Pyridines; Rats; Sarcoma, Yoshida; Tegafur; Vomiting | 1998 |
UFT: biochemical modulation for 5-fluorouracil (5-FU).
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase I as Topic; Drug Combinations; Fluorouracil; Humans; Lung Neoplasms; Neoplasms; Tegafur; Uracil | 1997 |
New drugs in the treatment of colorectal carcinoma.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Tegafur; Thiophenes; Topotecan; Trimetrexate; Uracil | 1998 |
Oral 5-FU alternatives for the treatment of head and neck cancer.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Etoposide; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Neoplasm Recurrence, Local; Tegafur; Uracil | 1998 |
Oral 5-FU analogues in the treatment of breast cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Deoxycytidine; Enzyme Inhibitors; Female; Fluorouracil; Humans; Tegafur; Uracil | 1998 |
Chemotherapy for gastric carcinoma: new and old options.
Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Capecitabine; Deoxycytidine; Docetaxel; Drug Combinations; Enzyme Inhibitors; Etoposide; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Oxonic Acid; Paclitaxel; Pyridines; Randomized Controlled Trials as Topic; Stomach Neoplasms; Taxoids; Tegafur; Uracil | 1998 |
The oral fluorouracil prodrugs.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Leucovorin; Oxonic Acid; Prodrugs; Pyridines; Tegafur; Uracil | 1998 |
Oral fluoropyrimidines in the treatment of colorectal cancer.
Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Enzyme Inhibitors; Fluorouracil; Humans; Oxidoreductases; Pyridines; Tegafur; Uracil | 1998 |
[Gastrointestinal cancer and oral anticancer agents].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents; Camptothecin; Drug Combinations; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Organoplatinum Compounds; Oxonic Acid; Prodrugs; Pyridines; Tegafur; Uracil | 1999 |
[Combination therapy of continuous venous infusion (CVI) of 5-FU and low dose consecutive cisplatin (CDDP), and the new oral anti-cancer drug S-1 for advanced gastro-intestinal cancer].
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Cycle; Cisplatin; Drug Administration Schedule; Drug Combinations; Fluorouracil; Gastrointestinal Neoplasms; Humans; Infusions, Intravenous; Oxonic Acid; Pyridines; Rats; Tegafur | 1999 |
[Oral fluoropyrimidines in oncology].
Topics: Administration, Oral; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials as Topic; Combined Modality Therapy; Deoxycytidine; Female; Floxuridine; Fluorouracil; Humans; Leucovorin; Male; Neoplasm Recurrence, Local; Neoplasms; Tegafur; Time Factors; Uracil | 1998 |
Fluoropyrimidines: a critical evaluation.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Leucovorin; Oxonic Acid; Pyridines; Tegafur; Uracil | 1999 |
Clinical implications of dihydropyrimidine dehydrogenase inhibition.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Dihydrouracil Dehydrogenase (NADP); Drug Evaluation; Enzyme Inhibitors; Fluorouracil; Humans; Neoplasms; Oxidoreductases; Tegafur; Uracil | 1999 |
The oral fluoropyrimidines in cancer chemotherapy.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Prodrugs; Tegafur | 1999 |
A review of the pharmacology and clinical activity of new chemotherapy agents for the treatment of colorectal cancer.
Topics: Antineoplastic Agents; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Glutamates; Guanine; Humans; Pemetrexed; Platinum Compounds; Pyridines; Quinazolines; Tegafur; Thiophenes; Uracil | 1999 |
Oral fluoropyrimidines: a closer look at their toxicities.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Tegafur; Uracil | 1999 |
The role of UFT in combined-modality therapy.
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Gastrointestinal Neoplasms; Humans; Infusions, Intravenous; Leucovorin; Neoplasms; Radiation-Sensitizing Agents; Tegafur; Uracil | 1999 |
[Combination chemotherapy with 5-FU and low-dose CDDP for urogenital tumors].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Infusions, Intravenous; Interferon-alpha; Kidney Neoplasms; Male; Tegafur; Uracil; Urinary Bladder Neoplasms | 1999 |
New drugs in therapy of colorectal cancer: preclinical studies.
Topics: Animals; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fluorouracil; Folic Acid Antagonists; Humans; Oxidoreductases; Prodrugs; Quinazolines; Tegafur; Thiophenes; Thymidine Phosphorylase; Thymidylate Synthase; Uracil | 1999 |
Oral fluoropoyrimidines.
Topics: Animals; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Enzyme Inhibitors; Fluorouracil; Folic Acid Antagonists; Humans; Leucovorin; Oxidoreductases; Oxonic Acid; Prodrugs; Pyridines; Tegafur; Uracil | 1999 |
Oxaliplatin: a new therapeutic option in colorectal cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Drug Synergism; Fluorouracil; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Tegafur; Thiophenes; Uracil | 1999 |
[New drugs in gastrointestinal oncology. Current status and future directions].
Topics: Antineoplastic Agents; Camptothecin; Capecitabine; Deoxycytidine; Docetaxel; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Gemcitabine; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Quinazolines; Taxoids; Tegafur; Thiophenes; Vinblastine; Vinorelbine | 1999 |
Tegafur/uracil + calcium folinate in colorectal cancer: double modulation of fluorouracil.
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Drug Combinations; Fluorouracil; Humans; Leucovorin; Tegafur; Uracil | 1999 |
Oral therapy for colorectal cancer: how to choose.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents; Biological Availability; Capecitabine; Colorectal Neoplasms; Decision Making; Deoxycytidine; Enzyme Inhibitors; Fluorouracil; Humans; Leucovorin; Tegafur; Uracil | 2000 |
Conceptual changes in cancer chemotherapy--biochemical modulation of 5-FU from bench to clinic.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Fluorouracil; Humans; Neoplasms; Tegafur | 2000 |
Preoperative therapy for local-regional gastric cancer: rationale and review of trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Doxorubicin; Etoposide; Fluorouracil; Humans; Methotrexate; Mitomycin; Preoperative Care; Stomach Neoplasms; Tegafur; Uracil | 2000 |
[Conceptual changes in cancer chemotherapy--biochemical modulation of 5-FU].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Drug Administration Schedule; Drug Combinations; Esophageal Neoplasms; Fluorouracil; Humans; Infusions, Intravenous; Oxonic Acid; Pancreatic Neoplasms; Pyridines; Rectal Neoplasms; Tegafur | 2000 |
Oral fluoropyrimidines in the treatment of colorectal cancer.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorouracil; Humans; Pyrimidines; Tegafur; Uracil | 2000 |
Progress in colorectal cancer chemotherapy: how far have we come, how far to go?
Topics: Camptothecin; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Humans; Immunotherapy; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Tegafur; Thiophenes | 2000 |
Mechanism of action of fluoropyrimidines: relevance to the new developments in colorectal cancer chemotherapy.
Topics: Antimetabolites, Antineoplastic; Colorectal Neoplasms; Fluorouracil; Folic Acid Antagonists; Humans; Leucovorin; Prodrugs; Tegafur; Uracil | 2000 |
Oral fluoropyrimidines in colorectal cancer.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Leucovorin; Oxonic Acid; Pyridines; Tegafur; Uracil | 2000 |
Conceptual changes in cancer chemotherapy: from an oral fluoropyrimidine prodrug, UFT, to a novel oral fluoropyrimidine prodrug, S-1, and low-dose FP therapy in Japan.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Drug Synergism; Drug Therapy; Fluorouracil; Humans; Oxonic Acid; Prodrugs; Pyridines; Tegafur; Uracil | 2000 |
UFT: mechanism of drug action.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Drug Resistance, Neoplasm; Drug Therapy, Combination; Fluorouracil; Humans; Tegafur; Thymidylate Synthase; Uracil | 2000 |
Oral DPD-inhibitory fluoropyrimidine drugs.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Drug Resistance, Neoplasm; Fluorouracil; Humans; Leucovorin; Oxidoreductases; Oxonic Acid; Pyridines; Tegafur; Uracil | 2000 |
[Current status and problem of adjuvant chemotherapy for curatively resected gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Melphalan; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Semustine; Stomach Neoplasms; Tegafur; Uracil | 2000 |
[Latest progress on chemotherapy for advanced gastric cancer].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Docetaxel; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Oxonic Acid; Paclitaxel; Pyridines; Randomized Controlled Trials as Topic; Stomach Neoplasms; Survival Rate; Taxoids; Tegafur | 2000 |
Oral fluoropyrimidines in cancer treatment.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Head and Neck Neoplasms; Humans; Lung Neoplasms; Neoplasms; Pyridines; Stomach Neoplasms; Tegafur; Uracil | 2000 |
[Fluorinated pyrimidines in oral treatment of advanced colorectal cancer].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Enzyme Inhibitors; Fluorouracil; Humans; Leucovorin; Oxidoreductases; Prodrugs; Pyrimidines; Tegafur; Uracil | 2000 |
Novel oral chemotherapy agents.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Dacarbazine; Deoxycytidine; Fluorouracil; Humans; Irinotecan; Neoplasms; Tegafur; Temozolomide; Uracil | 2000 |
[Progress in chemotherapy for colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cisplatin; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Oxonic Acid; Pyridines; Tegafur | 2000 |
[Recent advances is surgical adjuvant chemotherapy for colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Levamisole; Mitomycin; Randomized Controlled Trials as Topic; Semustine; Survival Rate; Tegafur; Uracil; Vincristine | 2000 |
Colorectal cancer: chemotherapy treatment overview.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Humans; Irinotecan; Leucovorin; Organoplatinum Compounds; Oxaliplatin; Randomized Controlled Trials as Topic; Tegafur; Treatment Outcome; Uracil | 2000 |
Other fluorinated pyrimidines in the treatment of solid tumors.
Topics: Antimetabolites, Antineoplastic; Clinical Trials as Topic; Drug Combinations; Fluorouracil; Humans; Neoplasms; Oxonic Acid; Pyridines; Tegafur | 2001 |
The oral fluorinated pyrimidines.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Biological Availability; Biotransformation; Capecitabine; Clinical Trials as Topic; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Enzyme Inhibitors; Fluorouracil; Humans; Neoplasms; Oxidoreductases; Prodrugs; Tegafur; Uracil | 2001 |
Integrating the oral fluoropyrimidines into the management of advanced colorectal cancer.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Humans; Irinotecan; Leucovorin; Pyrimidines; Quinazolines; Tegafur; Thiophenes; Uracil | 2001 |
[5-fluorouracil and dihydropyrimidine dehydrogenase].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Fluorouracil; Humans; Neoplasms; Oxidoreductases; Oxonic Acid; Pyridines; Tegafur; Uracil | 2001 |
Adjuvant chemotherapy after resection of hepatocellular carcinoma causes deterioration of long-term prognosis in cirrhotic patients: metaanalysis of three randomized controlled trials.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Administration Schedule; Drug Tolerance; Epirubicin; Female; Fluorouracil; Hepatectomy; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Multivariate Analysis; Neoplasm Recurrence, Local; Prognosis; Survival Rate; Tegafur; Treatment Outcome | 2001 |
New options for outpatient chemotherapy--the role of oral fluoropyrimidines.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Enzyme Inhibitors; Fluorouracil; Humans; Outpatients; Tegafur; Uracil | 2001 |
Oral uracil-tegafur: an alternative to intravenous 5-fluorouracil?
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Clinical Trials as Topic; Fluorouracil; Humans; Injections, Intravenous; Tegafur; Uracil | 2001 |
Answering patients' needs: oral alternatives to intravenous therapy.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Infusions, Intravenous; Patient Satisfaction; Quality of Life; Tegafur; Uracil | 2001 |
Nonsurgical treatment of hepatocellular carcinoma.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Capecitabine; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cryosurgery; Deoxycytidine; Drug Combinations; Ethanol; Fluorouracil; Humans; Hyperthermia, Induced; Infusions, Intra-Arterial; Injections, Intralesional; Interferons; Liver Cirrhosis; Liver Neoplasms; Octreotide; Radiopharmaceuticals; Radiotherapy Dosage; Tamoxifen; Tegafur; Uracil | 2001 |
[New therapeutic options in chemotherapy of advanced colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Carcinoma; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Disease-Free Survival; Fluorouracil; Humans; Irinotecan; Leucovorin; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Tegafur; Thiophenes; Uracil | 2001 |
New therapies, new directions: advances in the systemic treatment of metastatic colorectal cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Fluorouracil; Forecasting; Humans; Irinotecan; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Tegafur; Thiophenes; Trimetrexate; Uracil | 2001 |
[Oral fluoropyrimidines registered for the treatment of metastatic colorectal carcinoma: a possible gain].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Humans; Leucovorin; Neoplasm Metastasis; Pyrimidines; Tegafur; Uracil | 2002 |
[The principles of cancer treatment--changes in chemotherapy].
Topics: ADP Ribose Transferases; Animals; Antineoplastic Agents; Benzamides; Cisplatin; Drug Combinations; Fluorouracil; Genes, ras; Humans; Imatinib Mesylate; Insect Proteins; Lung Neoplasms; Mice; Neoplasms; Neoplastic Syndromes, Hereditary; Oxonic Acid; Piperazines; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Signal Transduction; Tegafur; Tumor Cells, Cultured | 2002 |
Clinical studies of three oral prodrugs of 5-fluorouracil (capecitabine, UFT, S-1): a review.
Topics: Administration, Oral; Antineoplastic Agents; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Neoplasms; Prodrugs; Pyridines; Tegafur; Treatment Outcome; Uracil | 2002 |
Oral fluoropyrimidine treatment of colorectal cancer.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Cost-Benefit Analysis; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Patient Compliance; Prodrugs; Pyridines; Tegafur; Treatment Outcome | 2001 |
[Recent advance in adjuvant therapy for breast cancer].
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Neoplasm Recurrence, Local; Prognosis; Survival Rate; Tamoxifen; Tegafur; Uracil | 2002 |
[Progress in postoperative adjuvant chemotherapy in gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cytarabine; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Lymphatic Metastasis; Meta-Analysis as Topic; Mitomycin; Stomach Neoplasms; Survival Analysis; Tegafur; Treatment Outcome | 2002 |
[Progress in adjuvant therapy for colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Leucovorin; Mitomycin; Radiotherapy, Adjuvant; Rectal Neoplasms; Tegafur; Uracil | 2002 |
[Weekly administration of paclitaxel with a short course of premedication for advanced or recurrent gastric cancer].
Topics: Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Paclitaxel; Premedication; Pyridines; Stomach Neoplasms; Tegafur | 2003 |
Palliative treatment of patients with colorectal cancer.
Topics: Antimetabolites, Antineoplastic; Camptothecin; Colorectal Neoplasms; Disease Progression; Enzyme Inhibitors; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Palliative Care; Quinazolines; Survival Analysis; Tegafur; Thiophenes; Thymidylate Synthase; Topoisomerase I Inhibitors; Treatment Outcome; Uracil | 2003 |
S-1 in gastric cancer: a comprehensive review.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Clinical Trials as Topic; Drug Combinations; Fluorouracil; Humans; Oxonic Acid; Pyridines; Quality of Life; Stomach Neoplasms; Tegafur; Treatment Outcome | 2003 |
Current topics of S-1 at the 74th Japanese Gastric Cancer Congress.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Clinical Trials, Phase II as Topic; Drug Combinations; Fluorouracil; Humans; Japan; Oxonic Acid; Pyridines; Stomach Neoplasms; Tegafur | 2003 |
Practical considerations in the use of oral fluoropyrimidines.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Oxonic Acid; Prodrugs; Pyridines; Tegafur; Uracil | 2003 |
[Oral fluoropyrimidines in the treatment of colorectal carcinoma].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Humans; Prodrugs; Tegafur; Uracil | 2003 |
[Recent advances in chemotherapy for digestive cancers with special references to gastric and colonic cancers].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colonic Neoplasms; Docetaxel; Drug Administration Schedule; Drug Combinations; Drug Delivery Systems; Fluorouracil; Humans; Irinotecan; Oxonic Acid; Paclitaxel; Pyridines; Stomach Neoplasms; Taxoids; Tegafur | 2003 |
[Controversial issues in chemotherapy for inoperable gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Combinations; Fluorouracil; Humans; Irinotecan; Oxonic Acid; Pyridines; Stomach Neoplasms; Survival Rate; Tegafur | 2003 |
[Controversy of treatment for advanced colorectal cancer--intermedisine].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Pyridines; Tegafur | 2003 |
[Chemotherapy for colon cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Colonic Neoplasms; Deoxycytidine; Fluorouracil; Humans; Irinotecan; Leucovorin; Organoplatinum Compounds; Oxaliplatin; Randomized Controlled Trials as Topic; Tegafur; Treatment Outcome; Uracil | 2003 |
[Intravenous continuous infusion of fluorouracil for treatment of metastatic colorectal cancer].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Infusions, Intravenous; Oxonic Acid; Prognosis; Pyridines; Tegafur; Thymidylate Synthase; Uracil | 2003 |
[Effect of systemic chemotherapy by 5-FU with low dose CDDP (in the hospital) and UFT with low dose CDDP (in outpatient clinic) in unresectable recurrent colorectal cancer].
Topics: Ambulatory Care Facilities; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neoplasms; Fluorouracil; Home Care Services, Hospital-Based; Hospitals; Humans; Neoplasm Recurrence, Local; Prognosis; Tegafur; Uracil | 2003 |
[Present status of chemotherapy for colorectal cancer in countries outside of Japan].
Topics: Administration, Oral; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cetuximab; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Evidence-Based Medicine; Fluorouracil; Humans; Irinotecan; Japan; Leucovorin; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Prognosis; Pyridines; Tegafur; United States; Uracil | 2003 |
Clinical and cost-effectiveness of capecitabine and tegafur with uracil for the treatment of metastatic colorectal cancer: systematic review and economic evaluation.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Cost-Benefit Analysis; Deoxycytidine; Drug Therapy, Combination; Fluorouracil; Humans; Neoplasm Metastasis; Tegafur; United Kingdom; Uracil | 2003 |
[Chemotherapy for colorectal carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Prospective Studies; Randomized Controlled Trials as Topic; Tegafur; Uracil | 2003 |
New developments in systemic chemotherapy in advanced colorectal cancer.
Topics: Administration, Oral; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Neoplasm Metastasis; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Tegafur; Thiophenes; Uracil | 2003 |
Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Maximum Tolerated Dose; Mitomycin; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Randomized Controlled Trials as Topic; Rectal Neoplasms; Survival Rate; Tegafur | 2004 |
The role of new agents in the treatment of colorectal cancer.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cetuximab; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Randomized Controlled Trials as Topic; Survival Analysis; Tegafur; Treatment Outcome; Uracil | 2004 |
[Oral 5-FU and digestive cancers].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorouracil; Gastrointestinal Neoplasms; Humans; Tegafur | 2004 |
Comparative pharmacology of oral fluoropyrimidines: a focus on pharmacokinetics, pharmacodynamics and pharmacomodulation.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Neoplasms; Prodrugs; Pyrimidinones; Tegafur; Uracil | 2004 |
Thymidylate synthase expression and prognosis of patients with gastrointestinal cancers receiving adjuvant chemotherapy: a review.
Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Clinical Trials as Topic; Combined Modality Therapy; Drug Resistance, Neoplasm; Fluorouracil; Gastrointestinal Neoplasms; Humans; Immunoblotting; Immunohistochemistry; Meta-Analysis as Topic; Neoplasm Recurrence, Local; Palliative Care; Pancreatic Neoplasms; Prognosis; RNA, Messenger; Survival Analysis; Tegafur; Thymidylate Synthase; Treatment Outcome | 2004 |
Thymidylate synthase: a critical target in cancer therapy?
Topics: Animals; Antineoplastic Agents; Apoptosis; Capecitabine; Cell Cycle; Cell Proliferation; Clinical Trials as Topic; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Leucovorin; Neoplasms; Oxonic Acid; Prodrugs; RNA, Messenger; Tegafur; Thymidylate Synthase | 2004 |
[Recent progress in chemotherapy for hepatocellular carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Disease Progression; Doxorubicin; Drug Interactions; Embolization, Therapeutic; Fluorouracil; Hepatectomy; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Interferon-alpha; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Tamoxifen; Tegafur; Uracil | 2004 |
[Advances in palliative and adjuvant chemotherapy of colon cancer].
Topics: Antineoplastic Agents; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Humans; Irinotecan; Leucovorin; Levamisole; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Tegafur; Uracil | 2004 |
[Effectiveness of chemoradiotherapy for three cases of squamous cell anal carcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Female; Floxuridine; Fluorouracil; Humans; Lymphatic Metastasis; Middle Aged; Radiotherapy, Adjuvant; Tegafur; Uracil | 2004 |
[CPT-11 combined chemotherapy for metastatic gastric cancer].
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Docetaxel; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Mitomycin; Oxonic Acid; Pyridines; Stomach Neoplasms; Taxoids; Tegafur | 2004 |
[Current combination chemotherapy containing paclitaxel for advanced, recurrent gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Drug Combinations; Floxuridine; Fluorouracil; Humans; Oxonic Acid; Paclitaxel; Pyridines; Quality of Life; Stomach Neoplasms; Tegafur | 2004 |
[Second-line chemotherapy for advanced colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Quality of Life; Survival Rate; Tegafur; Uracil | 2005 |
Commentary on Wang et al., "Pre-operative chemotherapy with oral tegafur-uracil and leucovorin for rectal cancer" (J Surg Oncol 89: 256-263).
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Preoperative Care; Rectal Neoplasms; Survival Rate; Tegafur; Uracil | 2005 |
[5 -fluoropyrimidines for treatment of biliary tract cancers].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Capecitabine; Clinical Trials as Topic; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Oxonic Acid; Pyridines; Pyrimidines; Tegafur; Uracil | 2006 |
Chemotherapy for colorectal cancer.
Topics: Antimetabolites, Antineoplastic; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Colorectal Neoplasms; Deoxycytidine; Drug Therapy, Combination; Fluorouracil; Humans; Irinotecan; Leucovorin; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Survival Rate; Tegafur; Uracil; Vitamin B Complex | 2005 |
[Adjuvant chemotherapy for colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Combinations; Evidence-Based Medicine; Fluorouracil; Guidelines as Topic; Humans; Leucovorin; Lymph Node Excision; Neoplasm Staging; Survival Rate; Tegafur; Uracil | 2006 |
The clinical and economic benefits of capecitabine and tegafur with uracil in metastatic colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Cost-Benefit Analysis; Deoxycytidine; Fluorouracil; Humans; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; State Medicine; Tegafur; Treatment Outcome; United Kingdom; Uracil | 2006 |
[Current evidence of irinotecan combination chemotherapy with TS-1 in patients with advanced colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Evidence-Based Medicine; Fluorouracil; Humans; Irinotecan; Leucovorin; Neoplasm Recurrence, Local; Oxonic Acid; Survival Rate; Tegafur | 2006 |
[Adjuvant treatment of colorectal cancer].
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Colonic Neoplasms; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Irinotecan; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Tegafur; Uracil | 2006 |
[Timeline from discovery of 5-FU to development of an oral anticancer agent S-1 and its drug concept].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Drug Administration Schedule; Drug Combinations; Drug Synergism; Fluorouracil; Humans; Neoplasms; Oxonic Acid; Pharmaceutical Preparations; Prodrugs; Tegafur | 2006 |
[Pharmacokinetics of S-1].
Topics: Administration, Oral; Adult; Aged; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Female; Fluorouracil; Humans; Kidney; Male; Middle Aged; Neoplasms; Oxonic Acid; Rats; Tegafur; Uracil | 2006 |
[S-1 as a single agent for colorectal cancer].
Topics: Administration, Oral; Anorexia; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Clinical Trials, Phase II as Topic; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leukopenia; Neutropenia; Oxonic Acid; Survival Rate; Tegafur | 2006 |
[Clinical efficacy of administration with S-1 alone for head and neck carcinoma].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials, Phase II as Topic; Drug Combinations; Fluorouracil; Head and Neck Neoplasms; Humans; Oxonic Acid; Tegafur; Uracil | 2006 |
[Chemotherapy in advanced gastric cancer--to ensure timely and appropriate switch to subsequent treatment options].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Clinical Trials, Phase III as Topic; Docetaxel; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Methotrexate; Oxonic Acid; Paclitaxel; Stomach Neoplasms; Survival Rate; Taxoids; Tegafur | 2007 |
[Clinical development of chemotherapy for advanced gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials, Phase III as Topic; Docetaxel; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Neoplasm Staging; Oxonic Acid; Stomach Neoplasms; Taxoids; Tegafur | 2007 |
[Standard chemotherapy for colonic neoplasms].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Fluorouracil; Humans; Irinotecan; Leucovorin; Organoplatinum Compounds; Oxaliplatin; Randomized Controlled Trials as Topic; Tegafur; Uracil | 2007 |
Chemotherapy of advanced gastric cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Clinical Trials as Topic; Deoxycytidine; Docetaxel; Drug Combinations; Fluorouracil; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Stomach Neoplasms; Taxoids; Tegafur; Uracil | 2007 |
Is there an optimal neoadjuvant therapy for locally advanced pancreatic cancer?
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Drug Combinations; Fluorouracil; Gemcitabine; Humans; Neoadjuvant Therapy; Oxonic Acid; Paclitaxel; Pancreatic Neoplasms; Randomized Controlled Trials as Topic; Tegafur | 2007 |
[Adjuvant chemotherapy for colorectal cancer in Japan-current state and problem areas].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Europe; Evidence-Based Medicine; Fluorouracil; Humans; Irinotecan; Japan; Leucovorin; Neoplasm Staging; Oxonic Acid; Practice Guidelines as Topic; Rectal Neoplasms; Tegafur; United States; Uracil | 2007 |
[Treatments of pancreatic cancer from the standpoint of medical oncology].
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Drug Administration Schedule; Drug Combinations; Erlotinib Hydrochloride; Fluorouracil; Gemcitabine; Humans; Oxonic Acid; Pancreatic Neoplasms; Quinazolines; Survival Rate; Tegafur | 2007 |
Medical treatment for advanced gastroesophageal adenocarcinoma.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials, Phase III as Topic; Deoxycytidine; Drug Combinations; Epirubicin; Esophageal Neoplasms; Fluorouracil; Humans; Oxonic Acid; Stomach Neoplasms; Tegafur; Treatment Outcome | 2007 |
The multidisciplinary management of gastrointestinal cancer. The integration of cytotoxics and biologicals in the treatment of metastatic colorectal cancer.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cell Death; Cell Survival; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; ErbB Receptors; Fluorouracil; Humans; Leucovorin; Neoplasm Metastasis; Tegafur; Treatment Outcome; Uracil; Vascular Endothelial Growth Factor A | 2007 |
The role of UFT in advanced gastric cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Drug Therapy, Combination; Fluorouracil; Humans; Pyrimidines; Stomach Neoplasms; Tegafur; Uracil | 2008 |
[Recent developments in systemic chemotherapy for hepatocellular carcinoma].
Topics: Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Capecitabine; Carcinoma, Hepatocellular; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Humans; Immunologic Factors; Liver Neoplasms; Tegafur | 2008 |
An update on biochemotherapy of advanced gastric and gastroesophageal adenocarcinoma.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Capecitabine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Deoxycytidine; Docetaxel; Drug Combinations; ErbB Receptors; Esophagogastric Junction; Fluorouracil; Humans; Irinotecan; Oxonic Acid; Radiation-Sensitizing Agents; Stomach Neoplasms; Taxoids; Tegafur; Vascular Endothelial Growth Factor A | 2008 |
[Progress in chemotherapy for advanced gastric cancer].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cisplatin; Clinical Trials, Phase III as Topic; Deoxycytidine; Docetaxel; Doxorubicin; Drug Combinations; Fluorouracil; Gefitinib; Humans; Irinotecan; Methotrexate; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Paclitaxel; Quinazolines; Stomach Neoplasms; Survival Rate; Taxoids; Tegafur; Trastuzumab | 2009 |
[The current status of adjuvant chemotherapy of colonic cancer].
Topics: Antimetabolites, Antineoplastic; Carnitine O-Palmitoyltransferase; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Delivery Systems; Fluorouracil; Humans; Tegafur | 2009 |
Oral uracil-tegafur plus leucovorin vs fluorouracil bolus plus leucovorin for advanced colorectal cancer: a meta-analysis of five randomized controlled trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Diarrhea; Fluorouracil; Humans; Infections; Leucovorin; Leukopenia; Mucositis; Neutropenia; Odds Ratio; Randomized Controlled Trials as Topic; Stomatitis; Survival Analysis; Tegafur; Uracil | 2011 |
Therapeutic usefulness of postoperative adjuvant chemotherapy with Tegafur-Uracil (UFT) in patients with breast cancer: focus on the results of clinical studies in Japan.
Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Deoxycytidine; Drug Combinations; Female; Floxuridine; Fluorouracil; Humans; Japan; Methotrexate; Oxonic Acid; Tegafur; Uracil | 2010 |
A review of analytical methods for the determination of 5-fluorouracil in biological matrices.
Topics: Antimetabolites, Antineoplastic; Chemistry Techniques, Analytical; Drug Monitoring; Fluorouracil; Humans; Prodrugs; Tegafur | 2010 |
S-1-based therapy versus 5-FU-based therapy in advanced gastric cancer: a meta-analysis.
Topics: Antineoplastic Agents; Drug Combinations; Fluorouracil; Humans; Middle Aged; Oxonic Acid; Randomized Controlled Trials as Topic; Stomach Neoplasms; Tegafur | 2011 |
A comprehensive review of S-1 in the treatment of advanced gastric adenocarcinoma.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials, Phase III as Topic; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Neoadjuvant Therapy; Neoplasm Staging; Oxonic Acid; Stomach Neoplasms; Tegafur | 2011 |
S-1 for the treatment of gastrointestinal cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Combinations; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Practice Guidelines as Topic; Tegafur | 2012 |
Second-line therapy in pancreatic cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Drug Combinations; Fluorouracil; Humans; Irinotecan; Oxonic Acid; Pancreatic Neoplasms; Randomized Controlled Trials as Topic; Tegafur | 2013 |
Applications of oral fluoropyrimidines in colon cancer: their role and new directions.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Colonic Neoplasms; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Enzyme Inhibitors; Fluorouracil; Humans; Oxaloacetates; Oxonic Acid; Tegafur; Uracil | 2003 |
Survival prolongation after treatment failure of first-line chemotherapy in patients with advanced gastric cancer: combined analysis of the Japan Clinical Oncology group trials JCOG9205 and JCOG9912.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Clinical Trials, Phase III as Topic; Drug Combinations; Female; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Male; Middle Aged; Oxonic Acid; Randomized Controlled Trials as Topic; Stomach Neoplasms; Survival Rate; Tegafur; Time Factors; Treatment Failure; Treatment Outcome; Young Adult | 2014 |
[Current status and future directions of chemotherapy for pancreatic cancer].
Topics: Albumins; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Deoxycytidine; Drug Combinations; Erlotinib Hydrochloride; Fluorouracil; Gemcitabine; Humans; Leucovorin; Organoplatinum Compounds; Oxonic Acid; Paclitaxel; Pancreatic Neoplasms; Quinazolines; Tegafur | 2013 |
S-1-based chemotherapy versus capecitabine-based chemotherapy as first-line treatment for advanced gastric carcinoma: a meta-analysis.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Disease Progression; Drug Combinations; Fluorouracil; Humans; Neoplasm Staging; Odds Ratio; Oxonic Acid; Publication Bias; Stomach Neoplasms; Tegafur; Time Factors; Treatment Outcome | 2013 |
Comparison of the efficacy and safety of S-1-based and capecitabine-based regimens in gastrointestinal cancer: a meta-analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Drug Combinations; Fluorouracil; Gastrointestinal Neoplasms; Humans; Odds Ratio; Oxonic Acid; Proportional Hazards Models; Publication Bias; Tegafur; Treatment Outcome | 2014 |
[A case of advanced sigmoid colon cancer with metastases in the liver and the paraaortic lymph nodes successfully treated with 5-FU/l-LV and FOLFOX4 followed by S-1 leading to long-term complete response].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Organoplatinum Compounds; Oxonic Acid; Sigmoid Neoplasms; Tegafur | 2014 |
S-1-based versus 5-FU-based chemotherapy as first-line treatment in advanced gastric cancer: a meta-analysis of randomized controlled trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Fluorouracil; Humans; Oxonic Acid; Publication Bias; Randomized Controlled Trials as Topic; Stomach Neoplasms; Tegafur; Treatment Failure | 2014 |
[Pharmacogenomics of the first-line treatment for gastric cancer: advances in the identification of genomic biomarkers for clinical response to chemotherapy].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biological Transport; Biomarkers; Biotransformation; Capecitabine; Combined Modality Therapy; Deoxycytidine; Drug Combinations; Drug Resistance, Neoplasm; Enzymes; Ethnicity; Fluorouracil; Gastrectomy; Humans; Mexico; Molecular Targeted Therapy; Organoplatinum Compounds; Oxonic Acid; Patient Selection; Pharmacogenetics; Precision Medicine; Prodrugs; Stomach Neoplasms; Tegafur | 2014 |
Survival benefit from S-1 as compared to Fluorouracil in Asian patients with advanced gastrointestinal cancer: a meta-analysis.
Topics: Antineoplastic Agents; Asian People; Drug Combinations; Fluorouracil; Gastrointestinal Neoplasms; Humans; Oxonic Acid; Randomized Controlled Trials as Topic; Tegafur; Treatment Outcome | 2014 |
The efficacy and toxicity of paclitaxel plus S-1 compared with paclitaxel plus 5-FU for advanced gastric cancer: a PRISMA systematic review and meta-analysis of randomized controlled trials.
Topics: Age Factors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Drug Combinations; Fluorouracil; Neoplasm Staging; Oxonic Acid; Risk Factors; Sex Factors; Stomach Neoplasms; Tegafur | 2014 |
Role of ABC transporters in fluoropyrimidine-based chemotherapy response.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP-Binding Cassette Transporters; Biological Availability; Biological Transport; Camptothecin; Capecitabine; Deoxycytidine; Drug Resistance, Neoplasm; Fluorouracil; Humans; Leucovorin; Neoplasms; Organoplatinum Compounds; Tegafur | 2015 |
[Adjuvant treatment for esophagogastric junction cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asia; Capecitabine; Carboplatin; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Deoxycytidine; Digestive System Surgical Procedures; Docetaxel; Drug Combinations; Esophageal Neoplasms; Esophagogastric Junction; Europe; Fluorouracil; Humans; Lymph Node Excision; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Paclitaxel; Stomach Neoplasms; Taxoids; Tegafur | 2015 |
A Meta-analysis Reveals S-1-based Chemotherapy Improves the Survival of Patients With Advanced Gastric Cancer.
Topics: Capecitabine; China; Clinical Trials as Topic; Deoxycytidine; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Male; Oxonic Acid; Severity of Illness Index; Stomach Neoplasms; Tegafur | 2015 |
[CURRENT STATE OF ADJUVANT TREATMENT FOR GASTRIC CANCER AFTER RADICAL SURGERY WITH EXTENDED LYMPH NODE DISSECTION].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Cisplatin; Deoxycytidine; Docetaxel; Drug Combinations; Fluorouracil; Gastrectomy; Humans; Leucovorin; Lymph Node Excision; Multicenter Studies as Topic; Oxaloacetates; Oxonic Acid; Paclitaxel; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Stomach Neoplasms; Survival Analysis; Survival Rate; Taxoids; Tegafur; Treatment Outcome | 2015 |
S-1-based regimens and the risk of oral and gastrointestinal mucosal injury: a meta-analysis with comparison to other fluoropyrimidines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Diarrhea; Drug Combinations; Fluorouracil; Humans; Intestinal Mucosa; Mouth Mucosa; Neoplasms; Oxonic Acid; Randomized Controlled Trials as Topic; Stomatitis; Tegafur | 2016 |
Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Gastrointestinal Diseases; Genetic Predisposition to Disease; Hematologic Diseases; Humans; Multivariate Analysis; Neoplasms; Odds Ratio; Pharmacogenetics; Phenotype; Polymorphism, Genetic; Risk Assessment; Risk Factors; Severity of Illness Index; Tegafur | 2015 |
High/positive expression of 5-fluorouracil metabolic enzymes predicts better response to S-1 in patients with gastric cancer: a meta-analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Drug Combinations; Fluorouracil; Humans; Orotate Phosphoribosyltransferase; Oxonic Acid; Stomach Neoplasms; Tegafur; Thymidine Phosphorylase; Thymidylate Synthase | 2016 |
Fluoropyrimidine-Based Chemotherapy as First-Line Treatment for Advanced Gastric Cancer: a Bayesian Network Meta-Analysis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Capecitabine; Disease-Free Survival; Drug Combinations; Fluorouracil; Humans; Middle Aged; Network Meta-Analysis; Oxonic Acid; Pyruvates; Stomach Neoplasms; Tegafur | 2016 |
Can S-1 replace fluorouracil for advanced gastric cancer? A PRISMA-compliant systematic review and meta-analysis.
Topics: Antimetabolites, Antineoplastic; Drug Combinations; Fluorouracil; Humans; Neoplasm Staging; Oxonic Acid; Prognosis; Stomach Neoplasms; Tegafur | 2016 |
The Efficacy and Safety of First-line Chemotherapy in Advanced Esophagogastric Cancer: A Network Meta-analysis.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Camptothecin; Capecitabine; Cisplatin; Disease-Free Survival; Drug Combinations; Esophageal Neoplasms; Esophagogastric Junction; Fluorouracil; Humans; Irinotecan; Methotrexate; Network Meta-Analysis; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Randomized Controlled Trials as Topic; Stomach Neoplasms; Survival Rate; Taxoids; Tegafur | 2016 |
Significant efficacy and well safety of apatinib in an advanced liver cancer patient: a case report and literature review.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Disease-Free Survival; Ethiodized Oil; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Pyridines; Tegafur | 2017 |
Oral versus intravenous fluoropyrimidines for colorectal cancer.
Topics: Administration, Oral; Adult; Antineoplastic Agents; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Floxuridine; Fluorouracil; Humans; Injections, Intravenous; Irinotecan; Male; Neoadjuvant Therapy; Organoplatinum Compounds; Palliative Care; Pyridines; Pyrimidines; Randomized Controlled Trials as Topic; Tegafur; Uracil | 2017 |
Capecitabine, 5-fluorouracil and S-1 based regimens for previously untreated advanced oesophagogastric cancer: A network meta-analysis.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Drug Combinations; Esophageal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Proportional Hazards Models; Publication Bias; Stomach Neoplasms; Tegafur; Treatment Outcome | 2017 |
Novel fluoropyrimidine-based chemotherapy for advanced well-differentiated neuroendocrine tumors: a clinical update.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Disease-Free Survival; Drug Combinations; Drug Therapy, Combination; Fluorouracil; Humans; Neoplasm Staging; Neuroendocrine Tumors; Oxonic Acid; Pyrimidines; Tegafur; Treatment Outcome | 2018 |
Comparative effectiveness of adjuvant treatments for resected gastric cancer: a network meta-analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Drug Combinations; Fluorouracil; Humans; Lymph Node Excision; Network Meta-Analysis; Oxaloacetates; Oxonic Acid; Stomach Neoplasms; Survival Analysis; Tegafur | 2018 |
Systemic 5-fluorouracil induced lupus erythematosus: a review of the literature.
Topics: Age Distribution; Aged; Antimetabolites, Antineoplastic; Capecitabine; Female; Fluorouracil; Humans; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Male; Middle Aged; Sex Distribution; Tegafur | 2019 |
Comparison of Platinum/S-1 and Platinum/5-Fluorouracil as First-Line Chemotherapy for Advanced Gastric or Gastroesophageal Junction Cancer: A Meta-Analysis Based on Randomized Controlled Trials.
Topics: Antineoplastic Agents; Coordination Complexes; Disease-Free Survival; Drug Combinations; Drug Therapy, Combination; Esophagogastric Junction; Fluorouracil; Gastrointestinal Neoplasms; Humans; Neoplasm Staging; Oxonic Acid; Platinum; Proportional Hazards Models; Randomized Controlled Trials as Topic; Stomach Neoplasms; Survival Analysis; Tegafur; Treatment Outcome | 2020 |
Dihydropyrimidine Dehydrogenase Testing prior to Treatment with 5-Fluorouracil, Capecitabine, and Tegafur: A Consensus Paper.
Topics: Antimetabolites, Antineoplastic; Austria; Capecitabine; Consensus; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Genetic Testing; Genotype; Germany; Humans; Male; Mutation; Neoplasms; Phenotype; Practice Guidelines as Topic; Switzerland; Tegafur | 2020 |
Relationships between pathological factors and long-term outcomes in patients enrolled in two prospective randomized controlled trials comparing the efficacy of oral tegafur-uracil with CMF (N·SAS-BC 01 trial and CUBC trial).
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Neoplasm Recurrence, Local; Prospective Studies; Randomized Controlled Trials as Topic; Tegafur | 2021 |
Uracil-tegafur vs fluorouracil as postoperative adjuvant chemotherapy in Stage II and III colon cancer: A nationwide cohort study and meta-analysis.
Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colectomy; Colonic Neoplasms; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Randomized Controlled Trials as Topic; Retrospective Studies; Taiwan; Tegafur | 2021 |
HER2-Directed Therapy in Advanced Gastric and Gastroesophageal Adenocarcinoma: Triumphs and Troubles.
Topics: Adenocarcinoma; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cisplatin; Clinical Trials as Topic; Drug Combinations; Drug Resistance, Neoplasm; Esophagogastric Junction; Fluorouracil; Humans; Irinotecan; Lapatinib; Oxaliplatin; Oxonic Acid; Paclitaxel; Receptor, ErbB-2; Stomach Neoplasms; Tegafur; Trastuzumab | 2021 |
Comparative Outcomes of First-Line Chemotherapy for Metastatic Pancreatic Cancer Among the Regimens Used in Japan: A Systematic Review and Network Meta-analysis.
Topics: Albumins; Antineoplastic Combined Chemotherapy Protocols; Comparative Effectiveness Research; Deoxycytidine; Drug Combinations; Fluorouracil; Gemcitabine; Humans; Irinotecan; Japan; Kaplan-Meier Estimate; Leucovorin; Neoplasm Metastasis; Network Meta-Analysis; Oxaliplatin; Oxonic Acid; Paclitaxel; Pancreatic Neoplasms; Progression-Free Survival; Proportional Hazards Models; Pyridines; Survival Rate; Tegafur; Treatment Outcome | 2022 |
233 trial(s) available for fluorouracil and tegafur
| Article | Year |
|---|---|
Chemotherapy for adenocarcinoma and large cell anaplastic carcinoma of the lung with ftorafur, adriamycin, and cis-dichlorodiammineplatinum(II).
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Humans; Lung Neoplasms; Middle Aged; Tegafur | 1978 |
Protracted oral chemotherapy with fluorinated pyrimidines as an adjuvant to surgical treatment for stomach cancer.
Topics: Administration, Oral; Adult; Aged; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Gastrectomy; Humans; Male; Middle Aged; Stomach Neoplasms; Tegafur | 1977 |
Phase II trial of ftorafur with mitomycin C versus ftorafur with methyl-CCNU in untreated colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Clinical Trials as Topic; Colonic Neoplasms; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycins; Nitrosourea Compounds; Rectal Neoplasms; Semustine; Tegafur | 1978 |
[Treatment of acute pancreatitis].
Topics: Acute Disease; Adolescent; Adult; Aged; Clinical Trials as Topic; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Pancreatectomy; Pancreatitis; Recurrence; Tegafur | 1979 |
[A prospective multi-centre study of the response of metastatic gastrointestinal tumours (author's transl)].
Topics: Adenocarcinoma; Carmustine; Fluorouracil; Gastrointestinal Neoplasms; Humans; Intestinal Neoplasms; Middle Aged; Pancreatic Neoplasms; Prognosis; Prospective Studies; Stomach Neoplasms; Tegafur | 1979 |
[Multicenter cooperative study of pre- and post-operative adjuvant chemotherapy in the treatment of colorectal cancer. North Kyushu Co-operative Study Group for Cancer Chemotherapy].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Fluorouracil; Humans; Lymph Nodes; Rectal Neoplasms; Suppositories; Survival Rate; Tegafur; Uracil | 1992 |
Early postoperative chemotherapy following noncurative resection for patients with advanced gastric cancer.
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Picibanil; Prospective Studies; Proteoglycans; Stomach Neoplasms; Tegafur; Uracil | 1992 |
[Evaluation of UFT administration in patients with ovarian cancer who had no evidence of disease after the initial therapy].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Humans; Middle Aged; Ovarian Neoplasms; Reoperation; Tegafur; Uracil | 1990 |
Doxorubicin and 5-fluorouracil versus doxorubicin and oral ftorafur in in the treatment of advanced gastric cancer--a phase II and III trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms; Survival Rate; Tegafur | 1990 |
[Adjuvant chemotherapy for gastric cancer--the third study. First report: central randomization by telephone method and analysis of patients' background factors].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Drug Administration Schedule; Fluorouracil; Humans; Japan; Mitomycin; Mitomycins; Multicenter Studies as Topic; Picibanil; Random Allocation; Stomach Neoplasms; Tegafur; Telephone | 1989 |
[Outcome of adjuvant mifurol chemotherapy in patients with resected colonic carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Drug Evaluation; Female; Fluorouracil; Follow-Up Studies; Humans; Japan; Male; Middle Aged; Mitomycin; Mitomycins; Multicenter Studies as Topic; Tegafur | 1989 |
Comparison of oral ftorafur and intravenous 5-fluorouracil in patients with advanced cancer of the stomach, colon or rectum.
Topics: Actuarial Analysis; Adenocarcinoma; Aged; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Prospective Studies; Random Allocation; Rectal Neoplasms; Stomach Neoplasms; Tegafur | 1986 |
Chemotherapy of advanced gastric carcinoma (stage IV): a randomized study of FAM versus 5-FU plus BCNU.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clinical Trials as Topic; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Prospective Studies; Random Allocation; Stomach Neoplasms; Tegafur | 1987 |
Oral ftorafur versus intravenous 5-fluorouracil. A comparative study in patients with colorectal cancer.
Topics: Administration, Oral; Adult; Aged; Blood Platelets; Colonic Neoplasms; Female; Fluorouracil; Humans; Injections, Intravenous; Leukocytes; Male; Middle Aged; Random Allocation; Rectal Neoplasms; Retrospective Studies; Tegafur | 1987 |
[Controlled study of MQF-OK therapy with FT and with UFT on various advanced gastrointestinal cancers. Hirosaki Cooperative Study Group of Cancer Chemotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone; Clinical Trials as Topic; Double-Blind Method; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Picibanil; Remission Induction; Stomach Neoplasms; Tegafur; Uracil | 1988 |
[Clinical evaluation of schizophyllan (SPG) in advanced gastric cancer (the second report)--a randomized controlled study].
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Administration Schedule; Fluorouracil; Glycosaminoglycans; Humans; Mitomycin; Mitomycins; Random Allocation; Sizofiran; Stomach Neoplasms; Tegafur | 1985 |
[Preliminary report of adjuvant chemo-endocrine therapy for breast cancer].
Topics: Adult; Anorexia; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymph Node Excision; Mastectomy; Middle Aged; Nausea; Postoperative Care; Tamoxifen; Tegafur | 1985 |
[Results of phase III study of lentinan].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Lentinan; Male; Middle Aged; Mitomycin; Mitomycins; Polysaccharides; Random Allocation; Rectal Neoplasms; Stomach Neoplasms; Tegafur | 1985 |
[A controlled study of surgical adjuvant chemoimmunotherapy with FT-207 and OK-432 for advanced stomach cancer: the fourth study].
Topics: Administration, Oral; Aged; Biological Products; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Gastrectomy; Humans; Injections, Subcutaneous; Male; Middle Aged; Picibanil; Postoperative Care; Prospective Studies; Random Allocation; Stomach Neoplasms; Tegafur | 1985 |
[Randomized study of long-term adjuvant chemotherapy with Futraful and mitomycin C in gastric cancer. A second study (fourth report)].
Topics: Clinical Trials as Topic; Drug Administration Schedule; Drug Synergism; Fluorouracil; Humans; Mitomycin; Mitomycins; Postoperative Care; Random Allocation; Stomach Neoplasms; Tegafur | 1985 |
[Chemotherapy of tumors of the gastrointestinal tract].
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Digestive System Neoplasms; Doxorubicin; Fluorouracil; Humans; Lomustine; Mitomycin; Mitomycins; Tegafur | 1985 |
[A randomized controlled study to compare 1-hexylcarbamoyl-5-fluorouracil (HCFU) and 1-(2-tetrahydrofuryl)-5-fluorouracil (Tegafur) for the prevention of post-operative recurrence of bladder cancer].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Postoperative Period; Random Allocation; Tegafur; Urinary Bladder; Urinary Bladder Neoplasms | 1985 |
[Results of the Hamburg ovarian blastoma study].
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Germany, West; Humans; Ifosfamide; Melphalan; Methotrexate; Neoplasm Staging; Ovarian Neoplasms; Prognosis; Random Allocation; Tegafur; Vincristine | 1985 |
Clinical trials on UFT in the treatment of head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Tegafur; Uracil | 1985 |
[Multidisciplinary therapy for esophageal carcinoma. Cooperative Study Group for Esophageal Carcinoma].
Topics: Alcohol Drinking; Bleomycin; Combined Modality Therapy; Esophageal Neoplasms; Female; Fluorouracil; Humans; Male; Prognosis; Smoking; Tegafur | 1984 |
Chemotherapy of large bowel cancer.
Topics: Antineoplastic Agents; Clinical Trials as Topic; Drug Therapy, Combination; Floxuridine; Fluorouracil; Follow-Up Studies; Humans; Intestinal Neoplasms; Liver Neoplasms; Semustine; Tegafur; Vincristine | 1982 |
Clinical trials with oral Futraful (INN: Tegafur) in cancer of the head and neck.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasm Recurrence, Local; Picibanil; Proteoglycans; Tegafur | 1981 |
A comparative study of oral tegafur and intravenous 5-fluorouracil in patients with metastatic colorectal cancer.
Topics: Administration, Oral; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Injections, Intravenous; Male; Nausea; Neoplasm Metastasis; Neutropenia; Random Allocation; Rectal Neoplasms; Tegafur; Thrombocytopenia | 1983 |
[Clinical study on combination chemotherapy of primary liver cancer].
Topics: Adult; Aged; Azirines; Carbazilquinone; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Random Allocation; Tegafur | 1983 |
Chemotherapy of disseminated gastric cancer. A joint effort of the Northern California Oncology Group and the Japanese Gastric Cancer Chemotherapy Group.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; California; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Japan; Male; Middle Aged; Stomach Neoplasms; Tegafur | 1983 |
[Randomized study on the long-term adjuvant chemotherapy with ftorafur and mitomycin C for stomach cancer: second report].
Topics: Drug Therapy, Combination; Fluorouracil; Humans; Mitomycin; Mitomycins; Postoperative Period; Random Allocation; Stomach Neoplasms; Tegafur | 1983 |
[Comparative study on two different types of tegafur for recurrent breast cancer].
Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Capsules; Delayed-Action Preparations; Drug Evaluation; Female; Fluorouracil; Humans; Middle Aged; Neoplasm Recurrence, Local; Tegafur | 1984 |
[Immunological approach and surgical treatment of cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Gastrectomy; Humans; Mitomycin; Mitomycins; Picibanil; Prospective Studies; Stomach Neoplasms; Tegafur | 1983 |
Clinical evaluation of prolonged chemotherapy combined with induction of hepatic drug-metabolizing enzymes as an adjuvant for treating patients with gastric cancer.
Topics: Clinical Trials as Topic; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Enzyme Induction; Fluorouracil; Glutathione; Humans; Microsomes, Liver; Phenobarbital; Random Allocation; Stomach Neoplasms; Tegafur; Time Factors | 1983 |
[Joint clinical Phase II study of SF-SP].
Topics: Clinical Trials as Topic; Colonic Neoplasms; Delayed-Action Preparations; Drug Evaluation; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Neoplasms; Pancreatic Neoplasms; Stomach Neoplasms; Tegafur | 1984 |
[A randomized study on the long-term adjuvant chemotherapy with ftorafur and mitomycin C for gastric cancer: the second study (III)].
Topics: Clinical Trials as Topic; Drug Administration Schedule; Fluorouracil; Humans; Mitomycin; Mitomycins; Postoperative Period; Random Allocation; Stomach Neoplasms; Tegafur | 1984 |
Levamisole in postoperative adjuvant immunochemotherapy for gastric cancer. A randomized controlled study of the MMC + Tegafur regimen with or without levamisole. Report I.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Immunotherapy; Levamisole; Male; Middle Aged; Mitomycin; Mitomycins; Stomach Neoplasms; Tegafur | 1984 |
[Evaluation of preoperative administration of N1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) suppository in surgical adjuvant chemotherapy for large bowel cancer].
Topics: Adult; Colonic Neoplasms; Colostomy; Female; Fluorouracil; Humans; Male; Middle Aged; Preoperative Care; Prospective Studies; Rectal Neoplasms; Suppositories; Tegafur | 1984 |
Comparison of 5-fluorouracil with ftorafur in adjuvant chemotherapies with combined inductive and maintenance therapies for gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Metastasis; Stomach Neoplasms; Tegafur | 1984 |
Methyl-CCNU and ftorafur in treatment of rectosigmoidal tumors and ftorafur capsules in treatment of colorectal tumors.
Topics: Capsules; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Nitrosourea Compounds; Rectal Neoplasms; Semustine; Sigmoid Neoplasms; Tegafur | 1981 |
Comparison of ftorafur with 5-fluorouracil in combination chemotherapy of advanced gastrointestinal carcinoma.
Topics: Adult; Carmustine; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Neoplasm Metastasis; Tegafur; Time Factors | 1981 |
Tamoxifen alone versus tamoxifen plus 1-(2-tetrahydrofuryl)-5-fluorouracil in the treatment of advanced breast cancer: a sequential trial.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Menopause; Middle Aged; Tamoxifen; Tegafur | 1981 |
[Effect of levamisole in postoperative adjuvant immunochemotherapy of stomach cancer--randomized controlled study of MMC-tegafur combination therapy with or without levamisole. 1].
Topics: Adjuvants, Immunologic; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Clinical Trials as Topic; Drug Therapy, Combination; Fluorouracil; Follow-Up Studies; Humans; Leukocyte Count; Levamisole; Lymphocytes; Middle Aged; Mitomycin; Mitomycins; Postoperative Care; Random Allocation; Stomach Neoplasms; Tegafur | 1982 |
[Effect of postoperative long-term chemotherapy of stomach cancer using mitomycin C and futraful--the secondary study (1)].
Topics: Aged; Antibiotics, Antineoplastic; Blood Cell Count; Body Weight; Clinical Trials as Topic; Drug Therapy, Combination; Fluorouracil; Humans; Mitomycin; Mitomycins; Postoperative Complications; Random Allocation; Stomach Neoplasms; Tegafur; Time Factors | 1982 |
[High tissue concentration of 5-FU reduced local recurrence after administration of tegafur suppositories].
Topics: Chemotherapy, Adjuvant; Fluorouracil; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Neoplasm Recurrence, Local; Preoperative Care; Suppositories; Tegafur | 1995 |
Randomized study with mitomycin C + 5-fluorouracil+cytosine arabinoside (MFC)+5-fluorouracil, MFC+tegafur and uracil (UFT), and MF+UFT in advanced gastric cancer: interinstitutional differences in a multicenter study in Japan.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cytarabine; Drug Administration Schedule; Female; Fluorouracil; Gastrectomy; Humans; Japan; Male; Middle Aged; Mitomycin; Stomach Neoplasms; Survival Rate; Tegafur; Uracil | 1995 |
[Usefulness of adjuvant chemotherapy with antimetabolites for cervical invasive cancer].
Topics: Adenocarcinoma; Administration, Oral; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Retrospective Studies; Survival Rate; Tegafur; Uterine Cervical Neoplasms | 1995 |
[Pharmacokinetic study of UFT in cancer patients receiving maintenance dialysis].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Fluorouracil; Humans; Kidney Failure, Chronic; Male; Middle Aged; Postoperative Care; Renal Dialysis; Stomach Neoplasms; Tegafur; Uracil | 1995 |
[5-FU concentrations in the blood and tumor tissue after 5'-DFUR or UFT administration in the patients with uterine cervical cancer].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Female; Floxuridine; Fluorouracil; Humans; Lymph Nodes; Middle Aged; Tegafur; Uracil; Uterine Cervical Neoplasms | 1995 |
[Combination chemotherapy with FP versus FEP in patients with advanced gastric cancer. Research group of gastric cancer chemotherapy].
Topics: Adenocarcinoma; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Etoposide; Female; Fluorouracil; Humans; Leukopenia; Lymphatic Metastasis; Male; Middle Aged; Proportional Hazards Models; Stomach Neoplasms; Survival Rate; Tegafur; Uracil; Vomiting | 1995 |
[The significance of portal infusion chemotherapy for prevention of recurrence in residual liver after hepatectomy for metastases from colorectal cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Hepatectomy; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Infusions, Intravenous; Liver Neoplasms; Male; Middle Aged; Mitomycin; Neoplasm Recurrence, Local; Neoplasm, Residual; Portal Vein; Tegafur; Uracil | 1994 |
Chemo-endocrine therapy for prostate cancer with bone metastasis. Nagasaki Prostate Cancer Research Group.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Epirubicin; Ethinyl Estradiol; Fluorouracil; Follow-Up Studies; Humans; Longitudinal Studies; Male; Middle Aged; Multivariate Analysis; Orchiectomy; Prognosis; Proportional Hazards Models; Prostatic Neoplasms; Survival Rate; Tegafur; Uracil | 1994 |
[Randomized controlled trial of MMC + UFT and MMC + 5-FU therapy in advanced gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Mitomycin; Quality of Life; Stomach Neoplasms; Survival Analysis; Tegafur; Uracil | 1994 |
[The usefulness of pre- and immediately postoperative chemotherapy in colorectal cancer].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Fluorouracil; Humans; Infusions, Intravenous; Lymphatic Metastasis; Mitomycin; Postoperative Care; Preoperative Care; Tegafur; Uracil | 1994 |
[A multicenter cooperative study on supplementary chemotherapy of uterocervical cancer. The Kyushu UFT Study Group of Uterocervical Cancer].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Middle Aged; Survival Rate; Tegafur; Uracil; Uterine Cervical Neoplasms | 1994 |
[A double-blind comparison of FUra plasma concentration by oral (UFT) vs continuous intravenous infusion (5-FU)].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Double-Blind Method; Fluorouracil; Humans; Infusions, Intravenous; Stomach Neoplasms; Tegafur; Uracil | 1993 |
[Determination of 5-FU tissue concentrations after oral UFT administration in tumors of the head and neck].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Middle Aged; Tegafur; Uracil | 1996 |
Treatment of patients with advanced gastric carcinoma with the combination of etoposide plus oral tegafur modulated by uracil and leucovorin. A phase II study of the ONCOPAZ Cooperative Group.
Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Anemia; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Diarrhea; Drug Administration Schedule; Etoposide; Fluorouracil; Humans; Injections, Intravenous; Leucovorin; Middle Aged; Nausea; Remission Induction; Stomach Neoplasms; Survival Rate; Tegafur; Vomiting | 1996 |
[Neoadjuvant therapy followed by administration of UFT for breast cancer patients].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; Humans; Middle Aged; Remission Induction; Tegafur; Uracil | 1996 |
[Comparative clinical study of adjuvant postoperative chemotherapy (5-FU, Tegafur, 5-FU + MMC) in curatively resected cases of gastric cancer. Study Group on 5-FU Oral Adjuvant Chemotherapy in Gastric Cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Fluorouracil; Gastrectomy; Humans; Male; Middle Aged; Mitomycin; Stomach Neoplasms; Survival Rate; Tegafur | 1996 |
[Combined chemotherapy with 5-FU and low dose CDDP for advanced or recurrent cancer of the digestive system and home anti-cancer chemotherapy].
Topics: Administration, Oral; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Digestive System Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Home Care Services, Hospital-Based; Humans; Infusion Pumps; Infusions, Intravenous; Male; Neoplasm Recurrence, Local; Quality of Life; Tegafur; Uracil | 1995 |
[Outpatient chemotherapy with continuous infusion of 5-fluorouracil (CI 5-FU) and intravenous bolus leucovorin (IVB LV) in advanced gastrointestinal cancer: the second report].
Topics: Administration, Oral; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Fluorouracil; Gastrointestinal Neoplasms; Home Care Services, Hospital-Based; Humans; Infusion Pumps; Infusions, Intravenous; Injections, Intravenous; Leucovorin; Male; Middle Aged; Quality of Life; Tegafur; Uracil | 1995 |
Advanced colorectal carcinoma: redefining the role of oral ftorafur.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Home Nursing; Humans; Karnofsky Performance Status; Leucovorin; Male; Middle Aged; Quality of Life; Tegafur | 1996 |
[Combination chemotherapy with 5-FU and CDDP or CDDP analog for head and neck cancer].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Middle Aged; Survival Rate; Tegafur; Uracil | 1996 |
A comparative, randomized trial of UFT and 5-fluorouracil in combination with cyclophosphamide and doxorubicin in the treatment of advanced breast cancer patients at The Philippines General Hospital.
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Combinations; Fluorouracil; Humans; Middle Aged; Neoplasm Metastasis; Tegafur; Uracil | 1997 |
Clinical application of biochemical modulation in cancer chemotherapy: biochemical modulation for 5-FU.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Fluorouracil; Humans; Japan; Tegafur; Uracil | 1997 |
[Low-dose cisplatin added to continuous infusion of 5-fluorouracil or oral administration of UFT for inoperable advanced or recurrent colorectal cancer].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Recurrence, Local; Rectal Neoplasms; Tegafur; Uracil | 1997 |
[Preoperative adjuvant chemotherapy with oral anticancer agents for stomach cancer].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Middle Aged; Multivariate Analysis; Stomach Neoplasms; Survival Rate; Tablets; Tegafur | 1997 |
Postsurgical sequential methotrexate, fluorouracil, and leucovorin for advanced colorectal carcinoma: a preliminary study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Mitomycin; Postoperative Period; Rectal Neoplasms; Survival Rate; Tegafur; Uracil | 1997 |
Scientific basis for the combination of tegafur with uracil.
Topics: Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Intestinal Absorption; Male; Middle Aged; Mitomycin; Postoperative Care; Stomach Neoplasms; Survival Analysis; Tegafur; Uracil | 1997 |
Phase I and pharmacokinetic evaluations of UFT plus oral leucovorin.
Topics: Administration, Oral; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Drug Combinations; Fluorouracil; Humans; Leucovorin; Neoplasms; Tegafur; Tetrahydrofolates; Uracil | 1997 |
5-FU or UFT combined with leucovorin for previously untreated metastatic colorectal Ca.
Topics: Adult; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Tegafur; Uracil | 1997 |
UFT plus leucovorin vs 5-FU plus leucovorin for metastatic colorectal cancer.
Topics: Adult; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Middle Aged; Tegafur; Uracil | 1997 |
Preoperative combined oral UFT plus leucovorin and radiation therapy for rectal cancer.
Topics: Antidotes; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Combinations; Feasibility Studies; Fluorouracil; Humans; Leucovorin; Radiotherapy Dosage; Rectal Neoplasms; Tegafur; Uracil | 1997 |
UFT in combination as adjuvant therapy for breast cancer. Grupo Oncologico de Sevilla Seville, Spain.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Combinations; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Postmenopause; Prednimustine; Premenopause; Spain; Survival Analysis; Tamoxifen; Tegafur; Uracil | 1997 |
Neoadjuvant therapy with cisplatin/fluorouracil vs cisplatin/UFT in locally advanced squamous cell head and neck cancer.
Topics: Adult; Aged; Alopecia; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Diarrhea; Drug Combinations; Female; Fluorouracil; Forecasting; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Staging; Neutropenia; Prospective Studies; Survival Rate; Tegafur; Treatment Outcome; Uracil | 1997 |
[Phase I study of S-1. S-1 Study Group].
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Oxonic Acid; Pyridines; Tegafur | 1997 |
Phase III randomized comparison of postoperative adjuvant chemotherapy with 2-year oral UFT (uracil/tegafur) versus six-cycle CMF (cyclophosphamide/methotrexate/5-fluorouracil) in high-risk node-negative breast cancer patients.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Tegafur; Uracil | 1998 |
A crossover study of oral administration of UFT in chronic liver disease: comparison of continuous and intermittent schedules.
Topics: Administration, Oral; Aged; Area Under Curve; Carcinoma, Hepatocellular; Chronic Disease; Cross-Over Studies; Diarrhea; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Gastritis; Gastrointestinal Hemorrhage; Humans; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Nausea; Tegafur; Treatment Outcome; Uracil | 1998 |
Effects of pharmacokinetic modulating chemotherapy using oral UFT and continuous venous 5FU infusion on the prognosis of irradiated rectal carcinomas with p53 overexpression.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Immunohistochemistry; Infusions, Intravenous; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Prospective Studies; Rectal Neoplasms; Survival Rate; Tegafur; Treatment Outcome; Tumor Suppressor Protein p53 | 1998 |
Phase III randomized comparison of postoperative adjuvant chemotherapy with 2-year oral uracil/tegafur versus 6-cycle cyclophosphamide/methotrexate/5-fluorouracil in high-risk node-negative breast cancer patients.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Risk; Survival Analysis; Tegafur; Uracil | 1998 |
Potential of the histoculture drug-response assay to contribute to cancer patient survival.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Multivariate Analysis; Prospective Studies; Stomach Neoplasms; Survival Rate; Tegafur; Tumor Stem Cell Assay; Uracil | 1995 |
Phase I and pharmacokinetic study of oral UFT, a combination of the 5-fluorouracil prodrug tegafur and uracil.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Area Under Curve; Cohort Studies; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Fatigue; Female; Fluorouracil; Humans; Male; Middle Aged; Nausea; Prodrugs; Tegafur; Uracil; Vomiting | 1996 |
[A study on the efficacy of combination chemoendocrine therapy consisting of cyclophosphamide, adriamycin, UFT, and tamoxifen for advanced or recurrent breast cancer].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Middle Aged; Neoplasm Recurrence, Local; Survival Rate; Tamoxifen; Tegafur; Treatment Outcome | 1999 |
Adjuvant mitomycin and fluorouracil followed by oral uracil plus tegafur in serosa-negative gastric cancer: a randomised trial. Gastric Cancer Surgical Study Group.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Fluorouracil; Gastrectomy; Humans; Infusions, Intravenous; Male; Middle Aged; Mitomycins; Stomach Neoplasms; Survival Rate; Tegafur; Uracil | 1999 |
Impact of uracil/tegafur plus oral calcium folinate on resource utilization.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorouracil; Health Resources; Health Services; Health Services Research; Hospitalization; Humans; Leucovorin; Outpatients; Tegafur; Uracil | 1999 |
UFT plus calcium folinate vs 5-FU plus calcium folinate in colon cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Disease-Free Survival; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Male; Middle Aged; Prospective Studies; Survival Rate; Tegafur; Treatment Outcome; Uracil | 1999 |
Using preoperative UFT to predict sensitivity to fluoropyrimidines in colorectal cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colectomy; Colonoscopy; Colorectal Neoplasms; Disease-Free Survival; Drug Hypersensitivity; Fluorouracil; Humans; Necrosis; Neoplasm Staging; Preoperative Care; Prospective Studies; Survival Rate; Tegafur; Treatment Outcome; Uracil | 1999 |
An early phase II study of oral S-1, a newly developed 5-fluorouracil derivative for advanced and recurrent gastrointestinal cancers. The S-1 Gastrointestinal Cancer Study Group.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Drug Combinations; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Oxonic Acid; Pyridines; Survival Analysis; Tegafur; Treatment Outcome | 1999 |
[Clinical trial of prophylactic hepatic arterial chemotherapy for liver metastases in patients with Dukes' C colorectal cancer].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Neoplasm Staging; Prospective Studies; Tegafur; Uracil | 1999 |
[Usefulness of pharmacokinetic modulating chemotherapy (PMC) for the postoperative adjuvant therapy of colorectal carcinoma: a preliminary report].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Prognosis; Random Allocation; Tegafur; Uracil | 1999 |
Prognosis after salvage chemotherapy for locally unresectable recurrent squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Salvage Therapy; Survival Rate; Tegafur; Uracil | 1999 |
[Interim report of JFMTC study no. 20 on the effectiveness of high dose CDDP plus 5-FU regimen as an adjuvant therapy for far-advanced cancer of the stomach].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Drug Evaluation; Fluorouracil; Humans; Stomach Neoplasms; Survival Rate; Tegafur; Uracil | 2000 |
Phase II study of S-1, a novel oral derivative of 5-fluorouracil, in advanced gastric cancer. For the S-1 Cooperative Gastric Cancer Study Group.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Oxonic Acid; Pyridines; Stomach Neoplasms; Tegafur; Treatment Outcome | 2000 |
Preoperative UFT administration for patients with advanced colorectal cancer--increased uptake of 5-fluorouracil by tumor tissue is a prognostic factor.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Colorectal Neoplasms; Female; Fluorouracil; Humans; Japan; Male; Middle Aged; Neoplasm Staging; Preoperative Care; Prognosis; Prospective Studies; Regression Analysis; Survival Analysis; Tegafur | 2000 |
[Randomized comparative study of CMF (cyclophosphamide, methotrexate and 5-fluorouracil) and UFT-tamoxifen regimens as adjuvant chemotherapy after surgery for breast cancer: Tochigi Prefectural Study Group for Post-Breast Cancer Adjuvant Chemotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Prospective Studies; Quality of Life; Survival Rate; Tamoxifen; Tegafur; Uracil | 2000 |
Results of pharmacokinetic modulating chemotherapy in combination with hepatic arterial 5-fluorouracil infusion and oral UFT after resection of hepatic colorectal metastases.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Synergism; Female; Fluorouracil; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Prospective Studies; Survival Analysis; Tegafur; Treatment Outcome; Uracil | 2000 |
UFT/leucovorin vs 5-FU/leucovorin in colon cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Disease-Free Survival; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Tegafur; Treatment Outcome; Uracil | 2000 |
Effect of food on the oral bioavailability of UFT and leucovorin in cancer patients.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Biological Availability; Colorectal Neoplasms; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Combinations; Fasting; Female; Fluorouracil; Food; Humans; Leucovorin; Male; Middle Aged; Tegafur; Tetrahydrofolates; Time Factors; Uracil | 2001 |
Patient preference and pharmacokinetics of oral modulated UFT versus intravenous fluorouracil and leucovorin: a randomised crossover trial in advanced colorectal cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Cross-Over Studies; Female; Fluorouracil; Humans; Injections, Intravenous; Leucovorin; Male; Middle Aged; Patient Satisfaction; Prospective Studies; Surveys and Questionnaires; Tegafur; Uracil | 2002 |
Oral fluoropyrimidines in the treatment of advanced colorectal cancer--results of two consecutive phase II trials.
Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Diarrhea; Drug Combinations; Fluorouracil; Humans; Leucovorin; Nausea; Survival Rate; Tegafur; Time Factors; Uracil | 2002 |
Clinical studies of three oral prodrugs of 5-fluorouracil (capecitabine, UFT, S-1): a review.
Topics: Administration, Oral; Antineoplastic Agents; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Neoplasms; Prodrugs; Pyridines; Tegafur; Treatment Outcome; Uracil | 2002 |
Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Quality of Life; Survival Rate; Tegafur; United States; Uracil | 2002 |
Randomized comparative study of tegafur/uracil and oral leucovorin versus parenteral fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease-Free Survival; Dose-Response Relationship, Drug; Europe; Female; Fluorouracil; Humans; Infusions, Parenteral; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Quality of Life; Survival Rate; Tegafur; Uracil | 2002 |
[Hepatic recurrence after prophylactic hepatic arterial infusion of 5-fluorouracil for Dukes' C colorectal cancer--correlation with the expression of dihydropyrimidine dehydrogenase in the primary tumor].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dihydrouracil Dehydrogenase (NADP); Enzyme-Linked Immunosorbent Assay; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Neoplasm Recurrence, Local; Oxidoreductases; Tegafur; Uracil | 2002 |
Randomized phase III trial of fluorouracil alone versus fluorouracil plus cisplatin versus uracil and tegafur plus mitomycin in patients with unresectable, advanced gastric cancer: The Japan Clinical Oncology Group Study (JCOG9205).
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Humans; Japan; Male; Middle Aged; Mitomycin; Prospective Studies; Stomach Neoplasms; Survival Rate; Tegafur; Uracil | 2003 |
[Interim report of JFMC study no. 23--phase III randomized clinical trial on the effectiveness of low-dose cisplatin plus 5-FU as a postoperative adjuvant chemotherapy for advanced gastric cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms; Survival Rate; Tegafur | 2002 |
Pharmacokinetics of S-1, an oral formulation of ftorafur, oxonic acid and 5-chloro-2,4-dihydroxypyridine (molar ratio 1:0.4:1) in patients with solid tumors.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Area Under Curve; Biological Availability; Dose-Response Relationship, Drug; Drug Combinations; Female; Fluorouracil; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Neoplasms; Oxonic Acid; Pyridines; Tegafur; Tissue Distribution; Uracil | 2003 |
Modelling of ftorafur and 5-fluorouracil pharmacokinetics following oral UFT administration. A population study in 30 patients with advanced breast cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Middle Aged; Models, Biological; Neoplasm Metastasis; Tegafur; Uracil; Vinblastine; Vinorelbine | 2003 |
A new regimen for S-1 therapy aiming at adverse reaction mitigation and prolonged medication by introducing a 1-week drug-free interval after each 2-week dosing session: efficacy and feasibility in clinical practice.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Feasibility Studies; Female; Fluorouracil; Follow-Up Studies; Humans; Japan; Male; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Patient Compliance; Pyridines; Retrospective Studies; Severity of Illness Index; Stomach Neoplasms; Tegafur; Time Factors; Treatment Outcome | 2003 |
Prediction of sensitivity to fluoropyrimidines by metabolic and target enzyme activities in gastric cancer.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Japan; Liver Neoplasms; Lymphatic Metastasis; Male; Mice; Mice, Inbred BALB C; Middle Aged; Multivariate Analysis; Neoplasm Staging; Oxidoreductases; Oxonic Acid; Peritoneal Neoplasms; Predictive Value of Tests; Pyridines; Retrospective Studies; Statistics as Topic; Stomach Neoplasms; Survival Analysis; Tegafur; Thymidine Phosphorylase; Thymidylate Synthase; Treatment Outcome; Uracil | 2003 |
Oral tegafur-uracil plus folinic acid versus intravenous 5-fluorouracil plus folinic acid as adjuvant chemotherapy of colon cancer.
Topics: Adenocarcinoma; Administration, Oral; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Injections, Intravenous; Leucovorin; Male; Middle Aged; Tegafur | 2003 |
[Preoperative chemoradiotherapy for locally advanced rectal cancer].
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colectomy; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Preoperative Care; Prognosis; Radiotherapy, Adjuvant; Radiotherapy, Conformal; Rectal Neoplasms; Suppositories; Tegafur | 2003 |
Randomized controlled trial of the efficacy of adjuvant immunochemotherapy and adjuvant chemotherapy for colorectal cancer, using different combinations of the intracutaneous streptococcal preparation OK-432 and the oral pyrimidines 1-hexylcarbamoyl-5-flu
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colectomy; Colonic Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Injections, Subcutaneous; Male; Middle Aged; Mitomycin; Neoplasm Staging; Picibanil; Pyrimidines; Radiotherapy, Adjuvant; Rectal Neoplasms; Survival Analysis; Tegafur; Treatment Outcome; Uracil | 2004 |
The effect of food on the pharmacokinetics of S-1 after single oral administration to patients with solid tumors.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Biological Availability; Cross-Over Studies; Eating; Female; Fluorouracil; Food; Humans; Kinetics; Male; Middle Aged; Neoplasms; Oxonic Acid; Phosphorylation; Pyridines; Tegafur; Time Factors | 2004 |
Concurrent and adjuvant chemotherapy for nasopharyngeal carcinoma: a factorial study.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Tegafur; Treatment Outcome; Uracil; Vincristine | 2004 |
Enhanced induction of apoptosis in lung adenocarcinoma after preoperative chemotherapy with tegafur and uracil (UFT).
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Chemotherapy, Adjuvant; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Lung Neoplasms; Male; Middle Aged; Preoperative Care; Prospective Studies; Tegafur; Uracil | 2004 |
Docetaxel (Taxotere), cisplatin, UFT, and leucovorin combination chemotherapy in advanced gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Stomach Neoplasms; Survival Analysis; Taxoids; Tegafur; Treatment Outcome; Uracil | 2005 |
Randomized crossover trial of intravenous 5-FU versus oral UFT both modulated by leucovorin: a one-centre experience.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Cross-Over Studies; Female; Fluorouracil; Humans; Injections, Intravenous; Leucovorin; Male; Patient Satisfaction; Prospective Studies; Tegafur; Uracil | 2005 |
Phase II study of irinotecan, leucovorin, 5-fluorouracil and tegafur/uracil for metastatic colorectal cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Palliative Care; Survival Analysis; Tegafur; Treatment Outcome; Uracil | 2005 |
[Pharmacokinetic modulating chemotherapy highly effective for colorectal carcinoma metastases to multiple organs].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Chronotherapy; Colorectal Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Tegafur; Uracil | 2005 |
[Phase I study of concurrent radiotherapy with TS-1 and vitamin A (TAR Therapy) for head and neck cancer].
Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Combinations; Fluorouracil; Head and Neck Neoplasms; Humans; Maximum Tolerated Dose; Middle Aged; Oxonic Acid; Pyridines; Quality of Life; Radiotherapy Dosage; Tegafur; Vitamin A | 2005 |
[Multicenter comparative study of the recurrence-inhibitory effect of oral fluoropyrimidine drugs in patients with colorectal cancer following curative resection].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Leukopenia; Lymphatic Metastasis; Male; Middle Aged; Mitomycin; Rectal Neoplasms; Survival Rate; Tegafur; Uracil | 2005 |
[Clinical evaluation of chemotherapy with irinotecan (CPT-11), l-leucovorin (l-LV), 5-fluorouracil (5-FU), and UFT for metastatic or recurrent colorectal cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Nausea; Rectal Neoplasms; Survival Rate; Tegafur; Uracil; Vomiting, Anticipatory | 2005 |
Randomised study of tegafur and oral leucovorin versus intravenous 5-fluorouracil and leucovorin in patients with advanced colorectal cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Male; Middle Aged; Survival Analysis; Tegafur; Treatment Outcome | 2005 |
Oral uracil and tegafur plus leucovorin compared with intravenous fluorouracil and leucovorin in stage II and III carcinoma of the colon: results from National Surgical Adjuvant Breast and Bowel Project Protocol C-06.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Neoplasms, Second Primary; Quality of Life; Tegafur; Uracil | 2006 |
Diverticular disease in patients with colon cancer: subgroup analysis of national surgical adjuvant breast and bowel project protocol C-06.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cohort Studies; Colonic Neoplasms; Diverticulum, Colon; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Prognosis; Retrospective Studies; Tegafur | 2006 |
[A randomized controlled study comparing uracil-tegafur (UFT)+tamoxifen (UFT+TAM therapy) with cyclophosphamide+adriamycin+5-fluorouracil (CAF therapy) for women with stage I , II, or IIIa breast cancer with four or more involved nodes in the adjuvant set
Topics: Anorexia; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Leukopenia; Lymph Nodes; Lymphatic Metastasis; Mastectomy; Middle Aged; Neoplasm Staging; Survival Rate; Tamoxifen; Tegafur; Uracil; Vomiting, Anticipatory | 2006 |
Biweekly oxaliplatin plus 1-day infusional fluorouracil/leucovorin followed by metronomic chemotherapy with tegafur/uracil in pretreated metastatic colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Patient Selection; Survival Analysis; Tegafur; Uracil | 2007 |
Quality of life in operable colon cancer patients receiving oral compared with intravenous chemotherapy: results from National Surgical Adjuvant Breast and Bowel Project Trial C-06.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Female; Fluorouracil; Health Status; Humans; Infusions, Intravenous; Leucovorin; Male; Middle Aged; Quality of Life; Tegafur; Uracil | 2007 |
A randomized phase II selection trial in patients with advanced/recurrent gastric cancer: Trial for Advanced Stomach Cancer (TASC).
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Fluorouracil; Humans; Neoplasm Recurrence, Local; Oxonic Acid; Paclitaxel; Stomach Neoplasms; Tegafur | 2007 |
Development of a pharmacokinetic model to optimize the dosage regimen of TS-1, a combination preparation of tegafur, gimeracil and oteracil potassium.
Topics: Administration, Oral; Algorithms; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Computer Simulation; Drug Combinations; Fluorouracil; Humans; Kidney; Kinetics; Models, Biological; Oxonic Acid; Pyridines; Renal Insufficiency; Tegafur; Time Factors; Uracil | 2007 |
Chronopharmacokinetics of oral tegafur and uracil in colorectal cancer patients.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Chronotherapy; Colorectal Neoplasms; Cross-Over Studies; Female; Fluorouracil; Humans; Male; Middle Aged; Tegafur; Therapeutic Equivalency; Uracil | 2008 |
Relationship between expression of vascular endothelial growth factor in tumor tissue from gastric cancers and chemotherapy effects: comparison between S-1 alone and the combination of S-1 plus CDDP.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cisplatin; Drug Combinations; Fluorouracil; Humans; Immunohistochemistry; Middle Aged; Oxonic Acid; Stomach Neoplasms; Tegafur; Vascular Endothelial Growth Factor A | 2007 |
Effect of gastrectomy on the pharmacokinetics of S-1, an oral fluoropyrimidine, in resectable gastric cancer patients.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Male; Middle Aged; Oxonic Acid; Pyridines; Stomach Neoplasms; Tegafur | 2007 |
Preoperative chemoradiotherapy for rectal cancer: randomized trial comparing oral uracil and tegafur and oral leucovorin vs. intravenous 5-fluorouracil and leucovorin.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Male; Middle Aged; Neoplasm Staging; Preoperative Care; Prospective Studies; Radiotherapy Dosage; Rectal Neoplasms; Survival Analysis; Tegafur; Uracil; Vitamin B Complex | 2008 |
Randomized phase II study of cisplatin and 5-FU continuous infusion (PF) versus cisplatin, UFT and vinorelbine (UFTVP) as induction chemotherapy in locally advanced squamous cell head and neck cancer (LA-SCHNC).
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Disease-Free Survival; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Middle Aged; Neoplasm Invasiveness; Proportional Hazards Models; Tegafur; Uracil; Vinblastine; Vinorelbine | 2008 |
Improved survival for hepatocellular carcinoma with portal vein tumor thrombosis treated by intra-arterial chemotherapy combining etoposide, carboplatin, epirubicin and pharmacokinetic modulating chemotherapy by 5-FU and enteric-coated tegafur/uracil: a p
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Hepatocellular; Chemotherapy, Cancer, Regional Perfusion; Epirubicin; Etoposide; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Pilot Projects; Portal Vein; Prospective Studies; Severity of Illness Index; Tablets, Enteric-Coated; Tegafur; Time Factors; Treatment Outcome; Uracil; Venous Thrombosis | 2007 |
A clinical pharmacokinetic analysis of tegafur-uracil (UFT) plus leucovorin given in a new twice-daily oral administration schedule.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Cross-Over Studies; Diarrhea; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Prodrugs; Sex Factors; Tegafur; Therapeutic Equivalency; Uracil | 2007 |
An anticancer drug sensitivity test to determine the effectiveness of UFT as postoperative adjuvant chemotherapy for patients with stage III colorectal cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Colorectal Neoplasms; Combined Modality Therapy; Disease-Free Survival; Drug Combinations; Drug Resistance, Neoplasm; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Neoplasm Staging; Postoperative Period; Survival Rate; Tegafur; Uracil | 2007 |
[Neoadjuvant chemotherapy for gastric cancer with peritoneal dissemination].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Combinations; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoadjuvant Therapy; Oxonic Acid; Peritoneal Neoplasms; Stomach Neoplasms; Survival Rate; Taxoids; Tegafur | 2007 |
Effectiveness of pharmacokinetic modulating chemotherapy combined with cisplatin as induction chemotherapy in resectable locally advanced head and neck cancer: phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Gastrointestinal Diseases; Head and Neck Neoplasms; Hematologic Diseases; Humans; Leucovorin; Male; Middle Aged; Radiotherapy, Adjuvant; Remission Induction; Salvage Therapy; Survival Analysis; Tegafur; Treatment Outcome; Uracil | 2008 |
CYP2A6 and the plasma level of 5-chloro-2, 4-dihydroxypyridine are determinants of the pharmacokinetic variability of tegafur and 5-fluorouracil, respectively, in Japanese patients with cancer given S-1.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Aryl Hydrocarbon Hydroxylases; Asian People; Cytochrome P-450 CYP2A6; Drug Combinations; Female; Fluorouracil; Genotype; Humans; Male; Middle Aged; Mixed Function Oxygenases; Neoplasms; Oxonic Acid; Polymorphism, Genetic; Pyridines; Tegafur | 2008 |
A randomised multicentre phase II trial of capecitabine vs S-1 as first-line treatment in elderly patients with metastatic or recurrent unresectable gastric cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Bone Neoplasms; Capecitabine; Deoxycytidine; Drug Combinations; Feasibility Studies; Female; Fluorouracil; Humans; Liver Neoplasms; Lymphatic Metastasis; Male; Neoplasm Recurrence, Local; Oxonic Acid; Peritoneal Neoplasms; Prognosis; Stomach Neoplasms; Survival Rate; Tegafur; Treatment Outcome | 2008 |
[Curative effects of FTQ combined with cisplatin in treatment of advanced gastric cancer: a multicenter study].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; Middle Aged; Oxonic Acid; Pyridines; Single-Blind Method; Stomach Neoplasms; Tegafur; Treatment Outcome | 2008 |
Phase II study of UFT with leucovorin plus hepatic arterial infusion with irinotecan, 5-fluorouracil and leucovorin for non-resectable liver metastases of colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Tegafur; Uracil | 2009 |
Phase I and pharmacokinetic study of tegafur-uracil/leucovorin combined with 5-fluorouracil/leucovorin and irinotecan in patients with advanced colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Middle Aged; Prognosis; Survival Rate; Tegafur; Tissue Distribution; Treatment Outcome | 2009 |
Oral uracil and tegafur compared with classic cyclophosphamide, methotrexate, fluorouracil as postoperative chemotherapy in patients with node-negative, high-risk breast cancer: National Surgical Adjuvant Study for Breast Cancer 01 Trial.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Staging; Quality of Life; Risk Factors; Tegafur; Uracil | 2009 |
Impacts of fluorouracil-metabolizing enzymes on the outcomes of patients treated with S-1 alone or S-1 plus cisplatin for first-line treatment of advanced gastric cancer.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Enzymes; Female; Fluorouracil; Humans; Male; Middle Aged; Oxonic Acid; Stomach Neoplasms; Survival Analysis; Tegafur; Treatment Outcome | 2010 |
Uracil-tegafur and tamoxifen vs cyclophosphamide, methotrexate, fluorouracil, and tamoxifen in post-operative adjuvant therapy for stage I, II, or IIIA lymph node-positive breast cancer: a comparative study.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Staging; Survival Rate; Tamoxifen; Tegafur; Uracil | 2009 |
Phase II study of S-1 combined with irinotecan (CPT-11) in patients with advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Oxonic Acid; Tegafur | 2009 |
Fluorouracil versus combination of irinotecan plus cisplatin versus S-1 in metastatic gastric cancer: a randomised phase 3 study.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Japan; Male; Middle Aged; Oxonic Acid; Proportional Hazards Models; Risk Assessment; Stomach Neoplasms; Tegafur; Time Factors; Treatment Outcome; Young Adult | 2009 |
Efficacy of oral tegafur-uracil (UFT) as adjuvant therapy as compared with classical cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) in early breast cancer: a pooled analysis of two randomized controlled trials (N.SAS-BC 01 trial and CUBC trial).
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Receptors, Estrogen; Tegafur; Uracil; Young Adult | 2010 |
[Effects of pharmacokinetic modulation chemotherapy (PMC) using oral UFT and venous 5-FU infusion as adjuvant chemotherapy for intrahepatic cholangiocellular carcinoma].
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Chemotherapy, Adjuvant; Cholangiocarcinoma; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Survival Rate; Tegafur; Uracil | 2009 |
Multicenter phase III comparison of cisplatin/S-1 with cisplatin/infusional fluorouracil in advanced gastric or gastroesophageal adenocarcinoma study: the FLAGS trial.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Esophageal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Oxonic Acid; Stomach Neoplasms; Survival Analysis; Tegafur; Treatment Outcome; Young Adult | 2010 |
Phase I/II study of irinotecan, UFT and leucovorin with hepatic arterial infusion using 5-FU in colorectal cancer patients with unresectable liver metastases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Survival Rate; Tegafur; Treatment Outcome; Uracil | 2011 |
Pharmacokinetics of S-1 and CYP2A6 genotype in Japanese patients with advanced cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Asian People; Cytochrome P-450 CYP2A6; Disease Progression; Drug Combinations; Female; Fluorouracil; Genotype; Humans; Male; Metabolic Clearance Rate; Middle Aged; Neoplasms; Oxonic Acid; Pharmacogenetics; Tegafur | 2010 |
Irinotecan plus S-1 (IRIS) versus fluorouracil and folinic acid plus irinotecan (FOLFIRI) as second-line chemotherapy for metastatic colorectal cancer: a randomised phase 2/3 non-inferiority study (FIRIS study).
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Kaplan-Meier Estimate; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Prodrugs; Tegafur | 2010 |
A pilot study of S-1 plus cisplatin versus 5-fluorouracil plus cisplatin for postoperative chemotherapy in histological stage IIIB-IV (M0) gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Chi-Square Distribution; Cisplatin; Disease-Free Survival; Drug Combinations; Feasibility Studies; Female; Fluorouracil; Gastrectomy; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Pilot Projects; Republic of Korea; Stomach Neoplasms; Tegafur; Time Factors; Treatment Outcome | 2012 |
Phase I study of S-1 plus nedaplatin in patients with advanced/recurrent head and neck cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Disease Progression; Drug Combinations; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Squamous Cell; Organoplatinum Compounds; Oxonic Acid; Squamous Cell Carcinoma of Head and Neck; Tegafur | 2010 |
Phase II study of combination chemotherapy with biweekly cetuximab and irinotecan for wild-type KRAS metastatic colorectal cancer refractory to irinotecan, oxaliplatin, and fluoropyrimidines.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Japan; Kaplan-Meier Estimate; Male; Middle Aged; Mutation; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Prospective Studies; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Tegafur; Treatment Failure | 2012 |
A phase I study evaluating the effect of CDHP as a component of S-1 on the pharmacokinetics of 5-fluorouracil.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cross-Over Studies; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Drug Interactions; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Oxonic Acid; Pyridines; Tegafur | 2011 |
Modified FOLFOX6 with oxaliplatin stop-and-go strategy and oral S-1 maintenance therapy in advanced colorectal cancer: CCOG-0704 study.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Tegafur | 2011 |
Phase 1 trial of S-1 in combination with sorafenib for patients with advanced hepatocellular carcinoma.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Carcinoma, Hepatocellular; Drug Combinations; Female; Fluorouracil; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Niacinamide; Oxonic Acid; Phenylurea Compounds; Pyridines; Sorafenib; Tegafur; Treatment Outcome | 2012 |
Phenylbutyrate mouthwash mitigates oral mucositis during radiotherapy or chemoradiotherapy in patients with head-and-neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cisplatin; Double-Blind Method; Eating; Female; Fluorouracil; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Humans; Male; Middle Aged; Mitomycin; Mouthwashes; Phenylbutyrates; Pilot Projects; Radiation Injuries; Radiotherapy Dosage; Stomatitis; Taiwan; Tegafur; Uracil; Weight Loss | 2012 |
Phase I study of cediranib in combination with cisplatin plus fluoropyrimidine (S-1 or capecitabine) in Japanese patients with previously untreated advanced gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appetite; Area Under Curve; Asian People; Capecitabine; Cisplatin; Deoxycytidine; Drug Administration Schedule; Fatigue; Female; Fluorouracil; Humans; Hyponatremia; Japan; Male; Metabolic Clearance Rate; Middle Aged; Neutropenia; Oxonic Acid; Quinazolines; Stomach Neoplasms; Tegafur; Treatment Outcome; Tumor Burden | 2012 |
A randomized phase II trial of S-1-oxaliplatin versus capecitabine-oxaliplatin in advanced gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Disease Progression; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Stomach Neoplasms; Tegafur; Treatment Outcome; Young Adult | 2012 |
High-dose radiotherapy (60 Gy) with oral UFT/folinic acid and escalating doses of oxaliplatin in patients with non-resectable locally advanced rectal cancer (LARC): a phase I trial.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Feasibility Studies; Female; Fluorouracil; Follow-Up Studies; Gamma Rays; Humans; Leucovorin; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Radiotherapy Dosage; Rectal Neoplasms; Survival Rate; Tegafur; Treatment Outcome; Uracil | 2012 |
A randomized phase-II trial comparing sequential and concurrent paclitaxel with oral or parenteral fluorinated pyrimidines for advanced or metastatic gastric cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female; Fluorouracil; Humans; Infusions, Parenteral; Male; Middle Aged; Oxonic Acid; Paclitaxel; Patient Compliance; Stomach Neoplasms; Tegafur; Treatment Outcome | 2012 |
Dose-effect relationship in chemoradiotherapy for locally advanced rectal cancer: a randomized trial comparing two radiation doses.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Brachytherapy; Denmark; Dose-Response Relationship, Radiation; Female; Fluorouracil; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Quebec; Radiotherapy Dosage; Rectal Neoplasms; Remission Induction; Tegafur | 2012 |
Usefulness of the preoperative administration of tegafur suppositories as alternative adjuvant chemotherapy for patients with resectable stage II or III colorectal cancer: a KODK4 multicenter randomized control trial.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Preoperative Care; Preoperative Period; Suppositories; Survival Rate; Tegafur | 2012 |
Pharmacokinetic study of S-1 in patients in whom inulin clearance was measured.
Topics: Aged; Antimetabolites, Antineoplastic; Area Under Curve; Creatinine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Glomerular Filtration Rate; Humans; Inulin; Kidney Function Tests; Male; Middle Aged; Oxonic Acid; Pyridines; Reference Values; Tegafur | 2012 |
A randomized phase II trial to elucidate the efficacy of capecitabine plus cisplatin (XP) and S-1 plus cisplatin (SP) as a first-line treatment for advanced gastric cancer: XP ascertainment vs. SP randomized PII trial (XParTS II).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cisplatin; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Middle Aged; Neoplasm Staging; Oxonic Acid; Stomach Neoplasms; Tegafur; Young Adult | 2012 |
A phase II study of docetaxel and oxaliplatin combination in recurrent gastric cancer patients after fluoropyrimidine and/or cisplatin adjuvant treatment: a Korean Cancer Study Group Protocol ST06-02.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Docetaxel; Drug Combinations; Female; Fluorouracil; Follow-Up Studies; Humans; Korea; Male; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Stomach Neoplasms; Survival Rate; Taxoids; Tegafur; Treatment Outcome | 2012 |
Phase II tailored S-1 regimen study of first-line chemotherapy in elderly patients with advanced and recurrent non-small cell lung cancer.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Body Surface Area; Carcinoma, Non-Small-Cell Lung; Creatinine; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Oxonic Acid; Tegafur; Treatment Outcome | 2012 |
S-1 plus oxaliplatin versus capecitabine plus oxaliplatin for first-line treatment of patients with metastatic colorectal cancer: a randomised, non-inferiority phase 3 trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Republic of Korea; Tegafur | 2012 |
[A phase II prospective randomized controlled trial of weekly paclitaxel combined with S-1 or fluorouracil for advanced gastric carcinoma].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Diarrhea; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Follow-Up Studies; Humans; Leukopenia; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Paclitaxel; Prospective Studies; Remission Induction; Stomach Neoplasms; Survival Rate; Tegafur | 2012 |
Pharmacokinetic evaluation of novel oral fluorouracil antitumor drug S-1 in Chinese cancer patients.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asian People; Cross-Over Studies; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Oxonic Acid; Pyridines; Tegafur; Therapeutic Equivalency | 2013 |
Safety analysis of weekly paclitaxel plus S-1 versus paclitaxel plus 5-fluorouracil/calcium folinate as first-line therapy in advanced gastric cancer: a multicenter open random phase II trial.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Oxonic Acid; Paclitaxel; Stomach Neoplasms; Tegafur; Young Adult | 2013 |
A phase I study of sorafenib in combination with S-1 plus cisplatin in patients with advanced gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Niacinamide; Oxonic Acid; Patient Compliance; Phenylurea Compounds; Sorafenib; Stomach Neoplasms; Tegafur; Treatment Outcome | 2014 |
Orally administered S-1 suppresses circulating endothelial cell counts in metastatic breast cancer patients.
Topics: 4-Butyrolactone; Administration, Oral; Adult; Aged; Antigens, CD34; Antimetabolites, Antineoplastic; Breast Neoplasms; Cell Count; Chemokine CCL2; Drug Combinations; Endothelial Cells; Female; Fluorouracil; Humans; Middle Aged; Neovascularization, Pathologic; Oxonic Acid; Tegafur; Thrombospondin 1; Treatment Outcome; Vascular Endothelial Growth Factor A | 2014 |
A multicentre randomised trial comparing weekly paclitaxel + S-1 with weekly paclitaxel + 5-fluorouracil for patients with advanced gastric cancer.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Leucovorin; Leukopenia; Male; Middle Aged; Multivariate Analysis; Nausea; Oxonic Acid; Paclitaxel; Stomach Neoplasms; Tegafur; Treatment Outcome; Young Adult | 2013 |
Impact of excision repair cross-complementing gene 1 (ERCC1) on the outcomes of patients with advanced gastric cancer: correlative study in Japan Clinical Oncology Group Trial JCOG9912.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Cisplatin; Dihydrouracil Dehydrogenase (NADP); DNA-Binding Proteins; Drug Combinations; Endonucleases; Female; Fluorouracil; Gene Expression; Humans; Irinotecan; Male; Oxonic Acid; Prognosis; RNA, Messenger; Stomach Neoplasms; Survival; Tegafur; Thymidylate Synthase; Vascular Endothelial Growth Factor A | 2013 |
Combination of cisplatin/S-1 in the treatment of patients with advanced gastric or gastroesophageal adenocarcinoma: Results of noninferiority and safety analyses compared with cisplatin/5-fluorouracil in the First-Line Advanced Gastric Cancer Study.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease Progression; Drug Combinations; Esophageal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Oxonic Acid; Stomach Neoplasms; Tegafur; Young Adult | 2013 |
5-Fluorouracil, mitomycin-c, and polysaccharide-k versus uracil-ftorafur and polysaccharide-K as adjuvant chemoimmunotherapy for patients with locally advanced gastric cancer with curative resection.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Fluorouracil; Humans; Immunotherapy; Male; Middle Aged; Mitomycin; Prevalence; Proteoglycans; Republic of Korea; Risk Factors; Stomach Neoplasms; Survival Rate; Tegafur; Treatment Outcome; Uracil | 2013 |
Leucovorin, fluorouracil, and oxaliplatin plus bevacizumab versus S-1 and oxaliplatin plus bevacizumab in patients with metastatic colorectal cancer (SOFT): an open-label, non-inferiority, randomised phase 3 trial.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusions, Intravenous; Japan; Kaplan-Meier Estimate; Leucovorin; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Tegafur; Treatment Outcome | 2013 |
Comparison of short-term efficacy and safety of TIROX and DCF regimens for advanced gastric cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Docetaxel; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Leukopenia; Lymphatic Metastasis; Male; Middle Aged; Neurotoxicity Syndromes; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Prospective Studies; Recurrence; Stomach Neoplasms; Taxoids; Tegafur; Treatment Outcome | 2014 |
Neoadjuvant chemoradiation therapy using concurrent S-1 and irinotecan in rectal cancer: impact on long-term clinical outcomes and prognostic factors.
Topics: Adult; Aged; Aged, 80 and over; Agranulocytosis; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradiotherapy; Diarrhea; Disease-Free Survival; Dose Fractionation, Radiation; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Leukopenia; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxonic Acid; Rectal Neoplasms; Tegafur; Treatment Outcome | 2014 |
Randomised phase III trial of adjuvant chemotherapy with oral uracil and tegafur plus leucovorin versus intravenous fluorouracil and levofolinate in patients with stage III colorectal cancer who have undergone Japanese D2/D3 lymph node dissection: final r
Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Japan; Leucovorin; Lymph Node Excision; Male; Middle Aged; Neoplasm Staging; Tegafur; Uracil; Young Adult | 2014 |
S-1 monotherapy as second line chemotherapy in advanced gastric cancer patients previously treated with cisplatin/infusional fluorouracil.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Oxonic Acid; Salvage Therapy; Stomach Neoplasms; Tegafur | 2014 |
Biweekly S-1 plus paclitaxel (SPA) as second-line chemotherapy after failure from fluoropyrimidine and platinum in advanced gastric cancer: a phase II study.
Topics: Administration, Oral; Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Asian People; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Injections, Intravenous; Male; Middle Aged; Neutropenia; Oxonic Acid; Paclitaxel; Platinum; Stomach Neoplasms; Tegafur; Treatment Outcome | 2014 |
A phase 3 non-inferiority study of 5-FU/l-leucovorin/irinotecan (FOLFIRI) versus irinotecan/S-1 (IRIS) as second-line chemotherapy for metastatic colorectal cancer: updated results of the FIRIS study.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Combinations; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Male; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Prognosis; Survival Rate; Tegafur | 2015 |
S-1 monotherapy as second line chemotherapy in advanced gastric cancer patients previously treated with cisplatin/infusional fluorouracil.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Cisplatin; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Oxonic Acid; Salvage Therapy; Stomach Neoplasms; Tegafur | 2014 |
A phase II study of S-1 chemotherapy with concurrent thoracic radiotherapy in elderly patients with locally advanced non-small-cell lung cancer: the Okayama Lung Cancer Study Group Trial 0801.
Topics: Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Neoplasm Metastasis; Oxonic Acid; Recurrence; Tegafur; Tomography, X-Ray Computed; Treatment Outcome | 2014 |
HPV Status Determines the Efficacy of Adjuvant Chemotherapy With S-1, an Oral Fluorouracil Prodrug, in Oropharyngeal Cancer.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Drug Combinations; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunohistochemistry; Male; Oropharyngeal Neoplasms; Oxonic Acid; Papillomaviridae; Prodrugs; Retrospective Studies; Tegafur; Treatment Outcome | 2015 |
S-1 plus oxaliplatin versus capecitabine plus oxaliplatin for the first-line treatment of patients with metastatic colorectal cancer: updated results from a phase 3 trial.
Topics: Adult; Aged; Antineoplastic Agents; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Survival Analysis; Tegafur; Treatment Outcome | 2014 |
Feasibility study of supportive care using lafutidine, a histamine H2 receptor antagonist, to prevent gastrointestinal toxicity during chemotherapy for gastric cancer.
Topics: Acetamides; Adenocarcinoma; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Diarrhea; Drug Combinations; Female; Fluorouracil; Gastrectomy; Gastrointestinal Tract; Histamine H2 Antagonists; Humans; Lymph Node Excision; Male; Middle Aged; Nausea; Oxonic Acid; Piperidines; Prospective Studies; Pyridines; Quality of Life; Stomach Neoplasms; Tegafur | 2014 |
Favorable effect of the combination of vinorelbine and dihydropyrimidine dehydrogenase‑inhibitory fluoropyrimidine in EGFR‑mutated lung adenocarcinoma: retrospective and in vitro studies.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; ErbB Receptors; Female; Fluorouracil; Gefitinib; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Mutation; Oxonic Acid; Quinazolines; Retrospective Studies; Tegafur; Treatment Outcome; Vinblastine; Vinorelbine | 2015 |
A randomized phase II study of combination therapy with S-1, oral leucovorin, and oxaliplatin (SOL) and mFOLFOX6 in patients with previously untreated metastatic colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Survival Rate; Tegafur; Treatment Outcome | 2015 |
Clinical Benefit and Health-Related Quality of Life Assessment in Patients Treated with Cisplatin/S-1 Versus Cisplatin/5-FU: Secondary End Point Results From the First-Line Advanced Gastric Cancer Study (FLAGS).
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Esophageal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Prognosis; Quality of Life; Stomach Neoplasms; Survival Rate; Tegafur; Young Adult | 2015 |
Randomized study of orally administered fluorinated pyrimidines (capecitabine versus S-1) in women with metastatic or recurrent breast cancer: Japan Breast Cancer Research Network 05 Trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Capecitabine; Deoxycytidine; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Japan; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Pyrimidines; Tegafur | 2015 |
[Immediate results of combined therapy for local recurrences of rectal cancer].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Radiation Injuries; Rectal Neoplasms; Severity of Illness Index; Tegafur; Treatment Outcome | 2015 |
Phase I study of postoperative radiotherapy concurrent with S-1 in patients with gastric cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Postoperative Care; Stomach Neoplasms; Tegafur | 2015 |
Randomised study of tegafur-uracil plus leucovorin versus capecitabine as first-line therapy in elderly patients with advanced colorectal cancer--TLC study.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Frail Elderly; Humans; Leucovorin; Male; Prospective Studies; Tegafur; Treatment Outcome; Vitamin B Complex | 2015 |
S-1 and irinotecan with or without bevacizumab versus 5-fluorouracil and leucovorin plus oxaliplatin with or without bevacizumab in metastatic colorectal cancer: a pooled analysis of four phase II studies.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Tegafur; Treatment Outcome | 2015 |
Study protocol of the TRICOLORE trial: a randomized phase III study of oxaliplatin-based chemotherapy versus combination chemotherapy with S-1, irinotecan, and bevacizumab as first-line therapy for metastatic colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Cost-Benefit Analysis; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Health Care Costs; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Quality of Life; Tegafur; Young Adult | 2015 |
Exploratory phase II trial in a multicenter setting to evaluate the clinical value of a chemosensitivity test in patients with gastric cancer (JACCRO-GC 04, Kubota memorial trial).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Drug Combinations; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fluorouracil; Gastrectomy; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Oxonic Acid; Stomach Neoplasms; Tegafur; Treatment Outcome | 2016 |
Randomized phase II study of second-line chemotherapy with the best available 5-fluorouracil regimen versus weekly administration of paclitaxel in far advanced gastric cancer with severe peritoneal metastases refractory to 5-fluorouracil-containing regime
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Drug Combinations; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Oxonic Acid; Paclitaxel; Peritoneal Neoplasms; Prognosis; Stomach Neoplasms; Survival Rate; Tegafur | 2016 |
S-1 plus cisplatin versus fluorouracil plus cisplatin in advanced gastric or gastro-esophageal junction adenocarcinoma patients: a pilot study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease-Free Survival; Drug Combinations; Esophagogastric Junction; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Oxonic Acid; Pilot Projects; Stomach Neoplasms; Tegafur | 2015 |
A Randomized Phase 2 Study of Neoadjuvant Chemoradiaton Therapy With 5-Fluorouracil/Leucovorin or Irinotecan/S-1 in Patients With Locally Advanced Rectal Cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradiotherapy, Adjuvant; Chi-Square Distribution; Confidence Intervals; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Induction Chemotherapy; Irinotecan; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Oxonic Acid; Rectal Neoplasms; Tegafur | 2015 |
Randomized phase II trial of TEGAFIRI (tegafur/uracil, oral leucovorin, irinotecan) compared with FOLFIRI (folinic acid, 5-fluorouracil, irinotecan) in patients with unresectable/recurrent colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Disease Progression; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Odds Ratio; Proportional Hazards Models; Recurrence; Tegafur; Treatment Failure; Treatment Outcome | 2016 |
Tumor 5-FU-related mRNA Expression and Efficacy of Oral Fluoropyrimidines in Adjuvant Chemotherapy of Colorectal Cancer.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma; Chemotherapy, Adjuvant; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Orotate Phosphoribosyltransferase; Oxonic Acid; RNA, Messenger; Tegafur; Tetrahydrofolate Dehydrogenase; Thymidine Phosphorylase; Thymidylate Synthase; Treatment Outcome | 2016 |
Phase II trial of S-1 plus leucovorin in patients with advanced gastric cancer and clinical prediction by S-1 pharmacogenetic pathway.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytochrome P-450 CYP2A6; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Orotate Phosphoribosyltransferase; Oxonic Acid; Pharmacogenomic Testing; Stomach Neoplasms; Tegafur | 2017 |
Maintenance treatment of Uracil and Tegafur (UFT) in responders following first-line fluorouracil-based chemotherapy in metastatic gastric cancer: a randomized phase II study.
Topics: Adult; Aged; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Stomach Neoplasms; Tegafur; Uracil; Young Adult | 2017 |
Comparative study of cisplatin-based definitive concurrent chemoradiotherapy with S-1 versus paclitaxel for unresectable locally advanced esophageal squamous cell carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Disease-Free Survival; Drug Combinations; Esophageal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Nausea; Neutropenia; Oxonic Acid; Paclitaxel; Remission Induction; Retrospective Studies; Tegafur; Vomiting | 2017 |
Randomized Controlled Trial of Adjuvant Chemotherapy with Fluoropyrimidines
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Floxuridine; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Stomach Neoplasms; Survival Analysis; Tegafur; Uracil | 2017 |
A phase III trial comparing oral S-1/cisplatin and intravenous 5-fluorouracil/cisplatin in patients with untreated diffuse gastric cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Esophagogastric Junction; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Metastasis; Oxonic Acid; Stomach Neoplasms; Survival Analysis; Tegafur | 2017 |
Patient-Reported Outcome Results from the Open-Label Randomized Phase III SELECT BC Trial Evaluating First-Line S-1 Therapy for Metastatic Breast Cancer.
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Bridged-Ring Compounds; Drug Combinations; Female; Fluorouracil; Health Status; Humans; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Patient Reported Outcome Measures; Quality of Life; Surveys and Questionnaires; Taxoids; Tegafur | 2018 |
S-1 and irinotecan plus bevacizumab versus mFOLFOX6 or CapeOX plus bevacizumab as first-line treatment in patients with metastatic colorectal cancer (TRICOLORE): a randomized, open-label, phase III, noninferiority trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Colorectal Neoplasms; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Kaplan-Meier Estimate; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Progression-Free Survival; Tegafur; Young Adult | 2018 |
Effects of ω-3 Fatty Acid Supplementation in Patients with Bile Duct or Pancreatic Cancer Undergoing Chemotherapy.
Topics: Aged; Aged, 80 and over; Albumins; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Cachexia; Camptothecin; Combined Modality Therapy; Deoxycytidine; Dietary Supplements; Drug Combinations; Fatty Acids, Omega-3; Female; Fluorouracil; Gemcitabine; Humans; Leucovorin; Male; Middle Aged; Nutritional Support; Organoplatinum Compounds; Oxonic Acid; Paclitaxel; Pancreatic Neoplasms; Pyridines; Tegafur | 2018 |
A randomized phase III study of hepatic arterial infusion chemotherapy with 5-fluorouracil and subsequent systemic chemotherapy versus systemic chemotherapy alone for colorectal cancer patients with curatively resected liver metastases (Japanese Foundatio
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Leucovorin; Liver; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Tegafur | 2018 |
A multicenter phase III study comparing Simultaneous Integrated Boost (SIB) radiotherapy concurrent and consolidated with S-1 versus SIB alone in elderly patients with esophageal and esophagogastric cancer - the 3JECROG P-01 study protocol.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; Drug Combinations; Esophageal Neoplasms; Esophagogastric Junction; Female; Fluorouracil; Humans; Male; Neoplasm Staging; Outcome Assessment, Health Care; Oxonic Acid; Prospective Studies; Radiotherapy, Intensity-Modulated; Stomach Neoplasms; Tegafur | 2019 |
Pharmacokinetic and bioequivalence study between two formulations of S-1 in Korean gastric cancer patients.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Chromatography, Liquid; Cross-Over Studies; Drug Compounding; Fluorouracil; Humans; Oxonic Acid; Pyridines; Republic of Korea; Stomach Neoplasms; Tandem Mass Spectrometry; Tegafur; Therapeutic Equivalency | 2019 |
Phase II study of S-1-based sequential combination chemotherapy including oxaliplatin plus bevacizumab and irinotecan with or without cetuximab for metastatic colorectal cancer: the SOBIC trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Cetuximab; Colorectal Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Oxaliplatin; Oxonic Acid; Progression-Free Survival; Tegafur; Treatment Outcome | 2020 |
Endoscopic radiofrequency ablation plus a novel oral 5-fluorouracil compound versus radiofrequency ablation alone for unresectable extrahepatic cholangiocarcinoma.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Extrahepatic; Cholangiocarcinoma; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Oxonic Acid; Prospective Studies; Radiofrequency Ablation; Tegafur; Treatment Outcome | 2020 |
Oral S-1 with 24-h Infusion of Irinotecan plus Bevacizumab versus FOLFIRI plus Bevacizumab as First-Line Chemotherapy for Metastatic Colorectal Cancer: An Open-Label Randomized Phase II Trial.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Male; Middle Aged; Oxonic Acid; Progression-Free Survival; Survival Rate; Tegafur; Young Adult | 2020 |
Phase I Study of Alternate-Day Administration of S-1, Oral Leucovorin, and Bevacizumab for Refractory Metastatic Colorectal Cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Oxonic Acid; Tegafur; Treatment Outcome | 2020 |
An Open-Label Single-Arm Phase II Study of Treatment with Neoadjuvant S-1 Plus Cisplatin for Clinical Stage III Squamous Cell Carcinoma of the Esophagus.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Combinations; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Female; Fluorouracil; Humans; Japan; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Oxonic Acid; Tegafur; Treatment Outcome | 2020 |
A Chinese Retrospective Multicenter Study of First-Line Chemotherapy for Advanced Pancreatic Cancer.
Topics: Adult; Aged; Albumins; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; China; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Gemcitabine; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Oxaliplatin; Oxonic Acid; Paclitaxel; Pancreatic Neoplasms; Progression-Free Survival; Retrospective Studies; Tegafur | 2020 |
Prospective evaluation and refinement of an S-1 dosage formula based on renal function for clinical application.
Topics: Aged; Antimetabolites, Antineoplastic; Dose-Response Relationship, Drug; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Nomograms; Oxonic Acid; Renal Insufficiency; Tegafur | 2021 |
Randomized phase II study comparing the efficacy and safety of SOX versus mFOLFOX6 as neoadjuvant chemotherapy without radiotherapy for locally advanced rectal cancer (KSCC1301).
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Combinations; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Oxaliplatin; Oxonic Acid; Prognosis; Rectal Neoplasms; Survival Rate; Tegafur | 2021 |
Combination therapy of bevacizumab with either S-1 and irinotecan or mFOLFOX6/CapeOX as first-line treatment of metastatic colorectal cancer (TRICOLORE): Exploratory analysis of RAS status and primary tumour location in a randomised, open-label, phase III
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Drug Combinations; Female; Fluorouracil; Genes, ras; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Mutation; Neoplasm Metastasis; Organoplatinum Compounds; Oxonic Acid; Proto-Oncogene Proteins B-raf; Quality of Life; Tegafur | 2021 |
Preoperative chemoradiotherapy using tegafur/uracil, oral leucovorin, and irinotecan (TEGAFIRI) followed by oxaliplatin-based chemotherapy as total neoadjuvant therapy for locally advanced rectal cancer: the study protocol for a phase II trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Clinical Trials, Phase II as Topic; Fluorouracil; Humans; Irinotecan; Leucovorin; Neoadjuvant Therapy; Neoplasm Staging; Oxaliplatin; Rectal Neoplasms; Tegafur; Treatment Outcome | 2023 |
962 other study(ies) available for fluorouracil and tegafur
| Article | Year |
|---|---|
Studies of antitumor agents. 1. Resolution of racemic 1-(tetrahydro-2-furanyl)-k-fluorouracil into the R and S isomers and examination of the biological activities of the isomers.
Topics: Animals; Bacteria; Fluorouracil; In Vitro Techniques; Male; Mice; Microsomes, Liver; Neoplasms, Experimental; Rats; Stereoisomerism; Structure-Activity Relationship; Tegafur | 1977 |
Studies on antitumor agents, 2. Syntheses and antitumor activities of 1-(tetrahydro-2-furanyl)-5-fluorouracil and 1,3-bis(tetrahydro-2-furanyl)-5-fluorouracil.
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Fluorouracil; Lethal Dose 50; Mice; Neoplasms, Experimental; Rats; Sarcoma 180; Sarcoma, Yoshida; Tegafur | 1978 |
Synthesis and biological activities of ftorafur metabolites. 3'- and 4'-hydroxyftorafur.
Topics: Animals; Antineoplastic Agents; Cell Division; Fluorouracil; HeLa Cells; Humans; Hydroxylation; Leukemia L1210; Stereoisomerism; Tegafur | 1979 |
Synthesis and antitumor activity of a series of ftorafur analogues: the effect of varying electronegativity at the 1'-position.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Female; Fluorouracil; Leukemia L1210; Leukemia P388; Mice; Tegafur | 1985 |
(o- and p-Nitrobenzyloxycarbonyl)-5-fluorouracil derivatives as potential conjugated bioreductive alkylating agents.
Topics: Animals; Cells, Cultured; Chemical Phenomena; Chemistry; Fluorouracil; Leukemia P388; Mice; Neoplasms, Experimental; Oxygen; Sarcoma 180; Structure-Activity Relationship | 1986 |
Fluorinated pyrimidine nucleosides. 4. Synthesis and antitumor testing of a series of 2',5'-dideoxy- and 2',3',5'-trideoxynucleosides of 5-fluorouracil.
Topics: Animals; Antineoplastic Agents; Deoxyuridine; Floxuridine; Fluorouracil; Mice; Sarcoma 180; Tegafur | 1980 |
Synthesis and biological evaluation of novel pyrimidine nucleoside analogues of 1,4-oxathiane, 1,4-dithiane, and 1,4-dioxane.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Chemical Phenomena; Chemistry; Fluorouracil; Heterocyclic Compounds; Humans; Mice; Neoplasms, Experimental; Pyrimidine Nucleosides | 1982 |
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability.
Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Male; Models, Biological; Molecular Weight; Rats; Rats, Inbred F344; Solubility; Structure-Activity Relationship | 1980 |
Studies on the synthesis of chemotherapeutics. 10. Synthesis and antitumor activity of N-acyl- and N-(alkoxycarbonyl)-5-fluorouracil derivatives.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Female; Fluorouracil; Lethal Dose 50; Leukemia P388; Mice; Neoplasms, Experimental | 1980 |
Thermodynamic aspects of hydrophobicity and the blood-brain barrier permeability studied with a gel filtration chromatography.
Topics: Blood-Brain Barrier; Chromatography, Gel; Hydrogen Bonding; Micelles; Permeability; Solubility; Thermodynamics | 1996 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Fluoropyrimidin-2,4-dihydroxy-5-isopropylbenzamides as antitumor agents against CRC and NSCLC cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Line, Tumor; Colorectal Neoplasms; Cytoprotection; Enzyme Activation; ErbB Receptors; Humans; Inhibitory Concentration 50; Lung Neoplasms; Mutation; Proteolysis; Proto-Oncogene Proteins c-akt | 2020 |
A new sulfated triterpene glycoside from the sea cucumber Colochirus quadrangularis, and evaluation of its antifungal, antitumor and immunomodulatory activities.
Topics: Animals; Antifungal Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Glycosides; Humans; Immunomodulation; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Saponins; Sea Cucumbers; Triterpenes | 2021 |
[Participation of non-specific rat liver microsome oxidases in destruction of Nl-furanidylpyrimidines].
Topics: Animals; Biotransformation; Fluorouracil; Male; Microsomes, Liver; NADP; Proadifen; Rats; Tegafur | 1977 |
Comparative studies on the metabolism of 2-(tetrahydrofuryl)-5-fluorouracil and 5-fluorouracil.
Topics: Alanine; Animals; DNA, Neoplasm; Fluorouracil; In Vitro Techniques; Male; Mice; Microsomes, Liver; NADP; Neoplasms, Experimental; Nucleic Acid Precursors; Rats; Tegafur; Tissue Distribution | 1977 |
[Effectiveness of ftorafur and hexamethylmelamine in advanced breast cancer].
Topics: Adult; Altretamine; Breast Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukopenia; Middle Aged; Neoplasm Metastasis; Tegafur; Triazines | 1978 |
Immunobiology and therapeutic manipulation of heterotransplanted Nb rat prostatic adenocarcinoma. Chemotherapy of autonomous tumor, 102 Pr, heterotransplanted into congenitally athymic (nude) mice and syngeneic Nb rats.
Topics: Adenocarcinoma; Animals; Fluorouracil; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Tegafur; Time Factors; Transplantation, Heterologous | 1979 |
Ftorafur: a self-limiting source of 5-fluorouracil?
Topics: Animals; Biotransformation; Fluorouracil; Hematopoietic Stem Cells; Lethal Dose 50; Leukemia L1210; Mice; Osteosarcoma; Sarcoma, Experimental; Tegafur | 1979 |
[Experimental study relating to the anti-cancer effect of FT-207 suppository (author's transl)].
Topics: Animals; Carcinoma, Squamous Cell; Female; Fluorouracil; Methylcholanthrene; Mice; Neoplasms, Experimental; Skin Neoplasms; Suppositories; Tegafur | 1979 |
[Long-term oral administration of anticancer drug (author's transl)].
Topics: Administration, Oral; Ambulatory Care; Antineoplastic Agents; Fluorouracil; Humans; Immunoglobulins; Middle Aged; Neoplasms; Tegafur; Time Factors | 1979 |
Studies on tetrahydrofuranyl-5-fluorouracils. 2. NMR studies of 1-(tetrahydro-2-furanyl)-, 3-(tetrahydro-2-furanyl)-, and 1,3-bis(tetrahydro-2-furanyl)-5-fluorouracils.
Topics: Fluorouracil; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Structure-Activity Relationship; Tegafur | 1979 |
[Mechanism of the chromosome damaging effect of ftorafur].
Topics: Animals; Cell Line; Chromosome Aberrations; Chromosomes; Cricetinae; Floxuridine; Fluorouracil; Mitosis; Mutagens; Tegafur; Thymidine | 1977 |
Futraful therapy on liver cancer.
Topics: Administration, Oral; Adult; Aged; Alkaline Phosphatase; Carcinoma, Hepatocellular; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; L-Lactate Dehydrogenase; Liver Neoplasms; Male; Middle Aged; Mitomycins; Neoplasm Metastasis; Remission, Spontaneous; Suppositories; Tegafur; Time Factors | 1977 |
[Characteristic pharmacodynamic in 1-(2-tetrahydrofuryl)-5-fluorouracil metabolism and its clinical efficacy in patients with primary hepatoma (author's transl)].
Topics: Adult; Aged; Carcinoma, Hepatocellular; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Tegafur | 1978 |
Decreased disappearance rate of 1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) from the blood and its unresponsiveness to tocophreyl nicotinate and indomethacin in patients with primary hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Fluorouracil; Humans; Indomethacin; Kinetics; Liver Cirrhosis; Liver Neoplasms; Microsomes, Liver; Nicotinic Acids; Tegafur; Vitamin E | 1979 |
High-pressure liquid chromatographic analysis of ftorafur and its metabolites in biological fluids.
Topics: Chromatography, High Pressure Liquid; Fluorouracil; Humans; Kinetics; Spectrophotometry, Ultraviolet; Tegafur | 1977 |
[Chemotherapy of cancer of the proximal region of the stomach].
Topics: Antineoplastic Agents; Drug Therapy, Combination; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms; Tegafur | 1977 |
[Therapeutic effect of ftorafur].
Topics: Adenocarcinoma; Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Female; Fluorouracil; Mammary Glands, Animal; Neoplasms; Rectal Neoplasms; Tegafur | 1977 |
[Action of ftorafur and 5-fluorouracil on the chromosomes of normal and tumorous cells in vivo].
Topics: Animals; Bone Marrow; Bone Marrow Cells; Chromosomes; Cricetinae; Dose-Response Relationship, Drug; Fluorouracil; Humans; Intestinal Neoplasms; Male; Mice; Mice, Inbred Strains; Mitosis; Neoplasm Transplantation; Tegafur; Thymectomy; Time Factors | 1977 |
Comparison of the actions of 5-fluorouracil and ftorafur in Escherichia coli.
Topics: Drug Resistance, Microbial; Escherichia coli; Fluorouracil; Tegafur; Time Factors; Uracil | 1977 |
[Analytical study of ftorafur-N 1-(2'-furanidil)-5-fluorouratil].
Topics: Chromatography, Thin Layer; Fluorouracil; Indicators and Reagents; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tegafur; Temperature | 1977 |
[Pharmacokinetics of ftorafur-2-14C in rats with Walker carcinosarcoma].
Topics: Animals; Carcinoma 256, Walker; Fluorouracil; Male; Mice; Tegafur | 1977 |
[Regression of a recurrent malignant glioma by combined chemoradiotherapy utilizing carboquone, FT-207 and telecobalt--report of a case (author's transl)].
Topics: Azirines; Brain Neoplasms; Carbazilquinone; Cobalt Radioisotopes; Drug Therapy, Combination; Fluorouracil; Frontal Lobe; Glioma; Humans; Infusions, Parenteral; Male; Middle Aged; Neoplasm Recurrence, Local; Quinones; Radioisotope Teletherapy; Tegafur | 1977 |
[Ftorafur concentration in the blood and urine of oncological patients].
Topics: Biopharmaceutics; Biotransformation; Breast Neoplasms; Dose-Response Relationship, Drug; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Kinetics; Neoplasm Metastasis; Neoplasms; Tegafur; Time Factors; Tissue Distribution | 1977 |
[A combined immuno-chemotherapy with futraful and picibanil for advanced cancer (author's transl)].
Topics: Aged; Biological Products; Drug Therapy, Combination; Female; Fluorouracil; Humans; Intestinal Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasms; Pancreatic Neoplasms; Picibanil; Stomach Neoplasms; Tegafur | 1977 |
Chemoimmunotherapy of metastatic large bowel cancer: nonspecific stimulation with BCG and levamisole.
Topics: BCG Vaccine; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Levamisole; Lomustine; Methotrexate; Neoplasm Metastasis; Rectal Neoplasms; Tegafur | 1977 |
Intermittent high single-dose ftorafur: phase I clinical trial with a pharmacologic-toxicity correlation.
Topics: Adult; Aged; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Tegafur | 1977 |
Phase II clinical trial of ftorafur in 5-fluorouracil-refractory colorectal cancer.
Topics: Adult; Aged; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Rectal Neoplasms; Tegafur | 1977 |
Iv methyl-CCNU and ftorafur with or without methanol-extracted residue of BCG for metastatic adenocarcinoma of the colon.
Topics: Adenocarcinoma; BCG Vaccine; Colonic Neoplasms; Fluorouracil; Humans; Injections, Intravenous; Leukopenia; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Semustine; Tegafur; Thrombocytopenia | 1977 |
GLC determination for ftorafur in biological fluids.
Topics: Chromatography, Gas; Drug Stability; Fluorouracil; Humans; Methods; Tegafur; Time Factors | 1977 |
Hydroxylated metabolies of R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil (Ftorafur) in rats and rabbits.
Topics: Animals; Chemical Phenomena; Chemistry; Female; Fluorouracil; Hydroxylation; Male; Rabbits; Rats; Stereoisomerism; Tegafur | 1978 |
[Use of fluorafur in the therapy of various chronic dermatoses].
Topics: Adult; Aged; Chronic Disease; Fluorouracil; Humans; Male; Middle Aged; Neurodermatitis; Psoriasis; Skin Diseases; Tegafur | 1977 |
[Chemoimmunotherapy with BCG and FT 207 (author's transl)].
Topics: Adult; Aged; BCG Vaccine; Erythrocyte Count; Female; Fluorouracil; Humans; Lymphocytes; Male; Middle Aged; Neoplasms; Tegafur | 1977 |
[Action of ftorafur on the chromosomes of normal and tumorous cells of the Djzungarian hamster in vitro].
Topics: Animals; Cell Line; Cells, Cultured; Chromatids; Chromosomes; Cricetinae; Fluorouracil; In Vitro Techniques; Metaphase; Neoplasms, Experimental; Tegafur | 1978 |
[Use of ftorafur in disseminated breast cancer].
Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Capsules; Female; Fluorouracil; Humans; Middle Aged; Neoplasm Metastasis; Tegafur | 1978 |
[A clinicopathological study on preoperative anticancer chemotherapy for gastric cancer (author's transl)].
Topics: Adult; Aged; Antineoplastic Agents; Cytarabine; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Middle Aged; Mitomycins; Preoperative Care; Stomach Neoplasms; Tegafur | 1978 |
Chemoimmunotherapy with BCG and FT 207 (II).
Topics: BCG Vaccine; Colonic Neoplasms; Fluorouracil; Humans; Rectal Neoplasms; Tegafur | 1978 |
Disposition and metabolism of 1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur) in humans.
Topics: Animals; Female; Fluorouracil; Half-Life; Humans; In Vitro Techniques; Male; Mice; Microsomes, Liver; Rats; Tegafur; Tissue Distribution | 1978 |
[Experimental study on the effects of local administration of anticancer drug to the regional lymph nodes (author's transl)].
Topics: Administration, Topical; Animals; Antineoplastic Agents; Dogs; Fluorouracil; Lymph Nodes; Neoplasms, Experimental; Tegafur; Tissue Distribution | 1978 |
Photosensitivity due to a fluorouracil derivative.
Topics: Fluorouracil; Humans; Lichen Planus; Male; Middle Aged; Photosensitivity Disorders; Tegafur; Ultraviolet Rays | 1978 |
Metabolism and disposition of Baker's antifolate (NSC-139105), ftorafur (NSC-148958), and dichloroallyl lawsone (NSC-126771) in man.
Topics: Antineoplastic Agents; Diffusion; Fluorouracil; Folic Acid Antagonists; Humans; Kinetics; Liver Diseases; Naphthoquinones; Tegafur; Time Factors; Triazines | 1978 |
[Chromosome aberrations and sister chromatid exchanges following exposure of cultured Chinese hamster cells to ftorafur and 5-fluorouracil].
Topics: Cell Line; Chromatids; Chromosome Aberrations; Chromosomes; Fluorouracil; Mutagens; Tegafur | 1978 |
[Comparative assessment of the effectiveness of the preparations CCNU, 5-fluorouracil, ftorafur and their combinations in inoperable stomach cancer].
Topics: Adenocarcinoma; Drug Therapy, Combination; Fluorouracil; Humans; Lomustine; Nitrosourea Compounds; Stomach Neoplasms; Tegafur | 1978 |
[Synthesis of 3-(tetrahydro-2-furanyl)-5-fluorouracil (author's transl)].
Topics: Antineoplastic Agents; Fluorouracil; Methods; Tegafur | 1978 |
Pharmacokinetics and metabolism of ftorafur in man.
Topics: Aged; Animals; Biotransformation; Chromatography, High Pressure Liquid; Female; Fluorouracil; Horses; Humans; In Vitro Techniques; Kinetics; Male; Middle Aged; Oxidation-Reduction; Rats; Tegafur; Thymidine Phosphorylase; Uridine Phosphorylase | 1979 |
In vivo effects of 5-fluorouracil and ftorafur[1-(tetrahydrofuran-2-yl)-5-fluorouracil] on murine mammary tumors and small intestine.
Topics: Animals; Body Weight; Cell Division; DNA; Female; Fluorouracil; Intestine, Small; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Tegafur | 1979 |
[Clinical studies on FT-207 enteric-coated granule--clinico-pharmacological evaluation and clinical experience (author's transl)].
Topics: Adult; Aged; Drug Evaluation; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Tablets, Enteric-Coated; Tegafur | 1979 |
Post-operative long-term adjuvant immunochemotherapy with mitomycin-C, PSK and FT-207 in gastric cancer patients.
Topics: Adjuvants, Immunologic; Basidiomycota; Drug Therapy, Combination; Fluorouracil; Gastrectomy; Humans; Immunotherapy; Mitomycins; Neoplasm Staging; Phytohemagglutinins; Postoperative Period; Proteoglycans; Skin Tests; Stomach Neoplasms; Tegafur; Time Factors; Tuberculin Test | 1979 |
Phase II evaluation of ftorafur in previously untreated colorectal cancer: a Southwest Oncology Group Study.
Topics: Adenocarcinoma; Adult; Aged; Central Nervous System; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms; Remission, Spontaneous; Tegafur; Time Factors | 1979 |
Human urinary metabolites of 1-(tetrahydro-2-furanyl)-5-fluorouracil (ftoraful).
Topics: Chemical Phenomena; Chemistry; Fluorouracil; Humans; Hydroxylation; Magnetic Resonance Spectroscopy; Mass Spectrometry; Tegafur | 1979 |
[Effect of ftorafur and 5-fluorouracil on the chromosomes of human tumor cell cultures].
Topics: Cells, Cultured; Chromosome Deletion; Chromosomes, Human; Colonic Neoplasms; Fluorouracil; Humans; Karyotyping; Neoplasms; Tegafur | 1979 |
Metabolism of 1,3-bis(tetrahydro-2-furanyl)-5-fluorouracil in mice.
Topics: Animals; Fluorouracil; Half-Life; Kidney; Liver; Male; Mice; Phenobarbital; Tegafur | 1979 |
Chemotherapy of gastrointestinal cancer.
Topics: Adjuvants, Pharmaceutic; Antineoplastic Agents; Fluorouracil; Gastrointestinal Neoplasms; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Prognosis; Tegafur | 1979 |
Effect of coadministration of uracil or cytosine on the anti-tumor activity of clinical doses of 1-(2-tetrahydrofuryl)-5-fluorouracil and level of 5-fluorouracil in rodents.
Topics: Administration, Oral; Animals; Cytosine; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Sarcoma 180; Tegafur; Tissue Distribution; Uracil | 1979 |
Detailed analysis of chromosome aberrations in human leukocyte induced by anti-malignant tumor agent (FT-207).
Topics: Cells, Cultured; Chromosome Aberrations; Female; Fluorouracil; Humans; Leukocytes; Male; Mitotic Index; Tegafur; Time Factors | 1978 |
Ftorafur, adriamycin, cyclophosphamide and BCG in the treatment of metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; BCG Vaccine; Body Weight; Breast Neoplasms; Central Nervous System; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Middle Aged; Tegafur; Vomiting | 1979 |
Phase I-II study of ftorafur and methyl-CCNU in advanced colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Bone Marrow; Colonic Neoplasms; Digestive System; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Humans; Middle Aged; Nervous System; Nitrosourea Compounds; Rectal Neoplasms; Semustine; Tegafur | 1979 |
5-Fluorouracil concentrations in human plasma following R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur) administration.
Topics: Fluorouracil; Humans; Infusions, Parenteral; Neoplasms; Tegafur; Time Factors | 1979 |
Evidence for toxicologic activity of ftorafur independent of conversion to 5-fluorouracil.
Topics: Animals; Digestive System; Fluorouracil; Hyperplasia; Intestinal Mucosa; Male; Mice; Tegafur | 1979 |
[Change of toxic and antineoplastic properties of ftorafur by means of action on nonspecific microsomal oxidase].
Topics: Animals; Drug Antagonism; Drug Synergism; Enzyme Induction; Fluorouracil; Leukemia, Experimental; Methylcholanthrene; Mice; Microsomes; Oxidoreductases; Phenobarbital; Premedication; Proadifen; Rauscher Virus; Spleen; Tegafur | 1979 |
A phase II trial of ftorafur: adriamycin and mitomycin-C (FAM II) in advanced gastric adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Bone Marrow; Central Nervous System; Digestive System; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycins; Remission, Spontaneous; Stomach Neoplasms; Tegafur | 1979 |
Chemotherapy for gastric cancer.
Topics: Antineoplastic Agents; Drug Therapy, Combination; Fluorouracil; Humans; Mitomycins; Stomach Neoplasms; Tegafur | 1979 |
Adriamycin, BCNU, ftorafur chemotherapy of pancreatic and biliary tract cancer.
Topics: Adult; Aged; Biliary Tract Neoplasms; Bone Marrow; Carmustine; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Middle Aged; Pancreatic Neoplasms; Remission, Spontaneous; Tegafur; Time Factors | 1979 |
[Effect of ftorafur on the chromosomes of human normal and tumor cells in vitro].
Topics: Burkitt Lymphoma; Cells, Cultured; Chromosomes, Human; Dose-Response Relationship, Drug; Fluorouracil; Humans; Lymphocytes; Mitosis; Tegafur | 1979 |
Chemoimmunotherapy with or without oophorectomy in premenopausal patients with advanced breast cancer.
Topics: BCG Vaccine; Breast Neoplasms; Castration; Cyclophosphamide; Doxorubicin; Drug Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Immunotherapy; Levamisole; Menopause; Neoplasm Metastasis; Tegafur | 1979 |
Quantitative gas-liquid chromatographic determination of ftorafur and 5-fluorouracil in biological specimens.
Topics: Animals; Chromatography, Gas; Fluorouracil; Gas Chromatography-Mass Spectrometry; Kinetics; Male; Mice; Tegafur; Water | 1979 |
The metabolism of ftorafur in the beagle dog and rhesus monkey.
Topics: Animals; Biotransformation; Dogs; Fluorouracil; Haplorhini; Macaca mulatta; Male; Tegafur; Time Factors | 1977 |
[A comparative study on the preoperative administration of 5-FU DS and FD-1 against gastric cancer--with special reference to histological findings (author's transl)].
Topics: Adult; Aged; Female; Fluorouracil; Furans; Humans; Lymphatic Metastasis; Male; Middle Aged; Preoperative Care; Pyrimidinones; Stomach; Stomach Neoplasms; Tegafur | 1979 |
[Clinical pharmacokinetics of 2-C14-ftorafur in patients with astrocytoma].
Topics: Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Cerebral Cortex; Fluorouracil; Humans; Injections, Intravenous; Tegafur | 1976 |
Drugs that make cancer retreat.
Topics: Antineoplastic Agents; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Nitrogen Mustard Compounds; Phenylalanine; Piperazines; Prospidium; Tegafur | 1976 |
Comparison of 5-fluorouracil and ftorafur. I. Quantitative and qualitative differences in toxicity to mice.
Topics: Animals; Blood Cell Count; Blood Platelets; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Half-Life; Immunity; Lethal Dose 50; Leukocytes; Male; Mice; Tegafur | 1976 |
Comparison of 5-fluorouracil and ftorafur. II. Therapeutic response and development of resistance in murine tumors.
Topics: Animals; Carcinoma; Cell Line; Drug Resistance; Drug Therapy, Combination; Female; Fluorouracil; Leukemia L1210; Leukemia, Experimental; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Melanoma; Methotrexate; Mice; Neoplasms, Experimental; Tegafur | 1976 |
[Comparative study of the effect of inhibitors of monoamine oxidase and ftorafur on the growth of de-differentiated astrocytoma].
Topics: Animals; Astrocytoma; Cerebellar Neoplasms; Drug Evaluation; Fluorouracil; Monoamine Oxidase Inhibitors; Neoplasms, Experimental; Rats; Serotonin; Tegafur | 1976 |
[Effect of millimeter band radio waves combined with ftorafur on the blood-forming system].
Topics: Animals; Bone Marrow; Bone Marrow Cells; Depression, Chemical; Fluorouracil; Hematopoiesis; Male; Mice; Radio Waves; Tegafur | 1976 |
Prognostic factors in patients with hepatocellular carcinoma receiving systemic chemotherapy.
Topics: alpha-Fetoproteins; Analysis of Variance; Antineoplastic Agents; Ascites; Bilirubin; Carcinoma, Hepatocellular; Cisplatin; Doxorubicin; Etoposide; Female; Fluorouracil; Follow-Up Studies; Humans; Interferon-gamma; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Multivariate Analysis; Prognosis; Regression Analysis; Risk Factors; Serum Albumin; Tegafur; Time Factors | 1992 |
Antitumor activity of two novel low immunosuppressive fluoropyrimidines UK-21 and UK-25.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Fluorouracil; Glycine; Leukemia L1210; Leukemia P388; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Organ Size; Sarcoma 180; Spleen; Tegafur; Thymus Gland; Uridine | 1992 |
[Concentration of 5-fluorouracil in the blood and tissues of gastric and colo-rectal cancer patients after oral administration of UFT].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorouracil; Humans; Lymph Nodes; Stomach Neoplasms; Tegafur; Uracil | 1992 |
[Blood concentrations of futraful, uracil and 5-fluorouracil (5-FU) after UFT administration in the various reconstructions after gastrectomy. Saitama UFT Research Group].
Topics: Anastomosis, Roux-en-Y; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Fluorouracil; Gastrectomy; Humans; Postoperative Period; Stomach Neoplasms; Tegafur; Uracil | 1992 |
[A study of urinary tegafur, 5-fluorouracil (5-FU) and uracil concentrations in the cases of gastric carcinoma for the confirmation of drug-taking compliance after UFT oral administration].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Compliance; Fluorouracil; Gastrectomy; Humans; Postoperative Period; Stomach Neoplasms; Tegafur; Uracil | 1992 |
Metabolism of tegafur in rat liver observed by in vivo 19F magnetic resonance spectroscopy and chromatography.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chromatography, High Pressure Liquid; Fluorine; Fluorouracil; Gas Chromatography-Mass Spectrometry; Liver; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred WKY; Tegafur | 1992 |
[Trend and problems of chemotherapy of stomach neoplasms with metastasis].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Fluorouracil; Humans; Mitomycin; Neoplasm Metastasis; Stomach Neoplasms; Tegafur | 1992 |
Chemotherapy for colorectal carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Lomustine; Mitomycin; Tegafur | 1992 |
Hyperthermia enhances the inhibition of tumor growth by 1-(2-tetrahydrofuryl)-5-fluorouracil/uracil (1:4) in tumors in mice and humans.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; Humans; Hyperthermia, Induced; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Phosphorylation; Sarcoma 180; Tegafur; Tumor Cells, Cultured | 1992 |
[Neo-adjuvant chemotherapy with tegafur suppository for rectal cancer--evaluation of the antitumor effects, tissue levels of 5-FU and inhibition of thymidylate synthase. Tochigi Colorectal Cancer Study Group].
Topics: Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Male; Rectal Neoplasms; Suppositories; Tegafur; Thymidylate Synthase | 1992 |
Metabolism of 1-(2-tetrahydrofuryl)-5-fluorouracil to 5-fluorouracil in partially hepatectomized rats.
Topics: Animals; Fluorouracil; Hepatectomy; Liver; Male; Rats; Rats, Inbred Strains; Tegafur; Tissue Distribution | 1992 |
[Histological evaluation of intra-arterial infusion and systemic chemotherapy of pancreatic carcinomas].
Topics: Adenocarcinoma; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Mitomycin; Neoplasm Staging; Pancreatic Neoplasms; Tegafur | 1992 |
[Chemosensitivity of head and neck squamous cell carcinomas using subrenal capsule assay--comparative assay of 5-FU, FT, UFT, and HCFU and immunohistochemical study].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Fluorouracil; Head and Neck Neoplasms; Immunohistochemistry; Male; Mice; Mice, Inbred C3H; Subrenal Capsule Assay; Tegafur; Uracil | 1992 |
[Pharmacokinetic studies on fluorinated pyrimidine in cancer cell and tissue].
Topics: Animals; Carcinoma, Ehrlich Tumor; Colonic Neoplasms; Esophageal Neoplasms; Female; Fluorouracil; Glucaric Acid; Humans; Liver; Male; Mice; Pancreatic Neoplasms; Stomach Neoplasms; Tegafur | 1992 |
[Pharmacokinetic study of tegafur in the hepatic tissue obtained from the patients with liver cancer].
Topics: Aged; Colonic Neoplasms; Fluorouracil; Humans; Liver; Liver Neoplasms; Middle Aged; Stomach Neoplasms; Tegafur; Thymidylate Synthase | 1992 |
[Thymidylate synthase inhibition and concentration of 5-fluorouracil after administration of UFT in human uroepithelial carcinomas].
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Female; Fluorouracil; Humans; Male; Middle Aged; Tegafur; Thymidylate Synthase; Tissue Distribution; Uracil; Ureteral Neoplasms; Urinary Bladder Neoplasms | 1991 |
[The dynamic indices of the natural killer cells in the chemotherapy of patients with digestive organ cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Digestive System Neoplasms; Female; Fluorouracil; Humans; Indomethacin; Interferons; Killer Cells, Natural; Male; Middle Aged; Tegafur | 1990 |
Effects of combined therapies with protein-bound polysaccharide (PSK, Krestin) and fluorinated pyrimidine derivatives on experimental liver metastases and on the immunologic capacities of the hosts.
Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Female; Fluorouracil; Hypersensitivity, Delayed; Immunity, Cellular; Kupffer Cells; Liver Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Organ Size; Phagocytosis; Proteoglycans; Splenectomy; Tegafur; Thymus Gland | 1991 |
[Comparative bioavailability of fluorouracil and its prodrug, ftorafur, following intra-arterial, intravenous and preoral administration].
Topics: Administration, Oral; Biological Availability; Fluorouracil; Half-Life; Humans; Injections, Intra-Arterial; Injections, Intravenous; Middle Aged; Prodrugs; Tegafur | 1991 |
A protein-bound polysaccharide immunomodulator, PSK, does not suppress the conversion from 1-(2-tetrahydrofuryl)-5-fluorouracil to 5-fluorouracil in patients with gastric cancer.
Topics: Antibiotics, Antineoplastic; Biotransformation; Depression, Chemical; Female; Fluorouracil; Humans; Injections, Intravenous; Male; Middle Aged; Proteoglycans; Stomach Neoplasms; Tegafur | 1991 |
Concentration of 5-fluorouracil in renal cells from cancer patients administered a mixture of 1-(2-tetrahydrofuryl)-5-fluorouracil and uracil.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Fluorouracil; Humans; Kidney; Kidney Neoplasms; Tegafur; Uracil | 1991 |
Induction of lethal infection with indigenous Escherichia coli in mice by fluorouracil.
Topics: Administration, Oral; Animals; Cephalothin; Escherichia coli; Escherichia coli Infections; Fluorouracil; Intestines; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Specific Pathogen-Free Organisms; Streptomycin; Tegafur; Time Factors | 1991 |
[Comparative studies on the antitumor activity of fluorinated pyrimidine derivatives against human bladder, cervical and ovarian cancer xenografts in nude mice].
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Floxuridine; Fluorouracil; Humans; Mice; Mice, Nude; Ovarian Neoplasms; Tegafur; Uracil; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms | 1991 |
Comparative antitumor activity of 5-fluorouracil and its prodrugs in combination with hyperthermia in vitro.
Topics: Antineoplastic Agents; Cell Survival; Floxuridine; Fluorouracil; Hot Temperature; Humans; Infant, Newborn; Prodrugs; Tegafur; Tumor Cells, Cultured | 1991 |
[Activation of tegafur by cultured rat hepatocytes].
Topics: Animals; Cells, Cultured; Drug Evaluation, Preclinical; Fluorouracil; Liver; Male; Rats; Tegafur; Tissue Survival | 1991 |
[Regional immunochemotherapy for liver metastasis of esophageal cancer in a patient with variant hepatic artery].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Esophageal Neoplasms; Fluorouracil; Hepatic Artery; Humans; Infusion Pumps; Infusions, Intra-Arterial; Injections, Intramuscular; Liver Neoplasms; Male; Middle Aged; Picibanil; Tegafur; Uracil | 1991 |
Effect of L-cysteine on plasma concentration and urinary excretion of 1-(tetrahydro-2-furanyl)-5-fluorouracil metabolites.
Topics: Animals; Cysteine; Fluorouracil; Kidney Tubules; Male; Rats; Rats, Inbred Strains; Tegafur | 1991 |
[Studies on 5-FU concentration in serum and prostate cancer tissue after oral administration of UFT].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Male; Prostatectomy; Prostatic Neoplasms; Tegafur; Uracil | 1991 |
Hepatic recurrence not prevented with low-dosage long-term intraportal 5-FU infusion after resection of colorectal liver metastasis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Fluorouracil; Hepatectomy; Humans; Infusions, Intravenous; Injections, Intravenous; Liver Neoplasms; Male; Middle Aged; Mitomycin; Neoplasm Recurrence, Local; Portal Vein; Tegafur; Time Factors | 1991 |
[High-dose Tegafur (FT) for primary lung cancer: a phase I trial].
Topics: Drug Administration Schedule; Drug Evaluation; Fluorouracil; Humans; Infusions, Intravenous; Lung Neoplasms; Middle Aged; Tegafur | 1991 |
[Possible cardiotoxicity induced by orally administered fluoropyrimidines].
Topics: Administration, Oral; Aged; Fluorouracil; Heart Diseases; Humans; Male; Middle Aged; Tegafur | 1990 |
[Usage of urine FT levels for medication compliance in head and neck cancer with administration of UFT].
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Tegafur; Uracil | 1990 |
[Tissue UFT distribution and histological changes following UFT administration in metastatic liver cancer cases].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Tegafur; Uracil | 1990 |
[Macrocytic anemia as a possible adverse effect of fluoropyrimidines].
Topics: Anemia, Macrocytic; Antineoplastic Combined Chemotherapy Protocols; Erythrocyte Indices; Female; Fluorouracil; Folic Acid; Humans; Male; Retrospective Studies; Stomach Neoplasms; Tegafur; Uracil; Vitamin B 12 | 1990 |
[Evaluation of intraperitoneal cancer chemotherapy using an implantable reservoir in patients with peritonitis carcinomatosa].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Cisplatin; Colorectal Neoplasms; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Male; Middle Aged; Mitomycin; Mitomycins; Peritonitis; Prognosis; Stomach Neoplasms; Tegafur | 1990 |
[Evaluation of subselective intraarterial infusion chemotherapy in advanced gastric cancer and recurrence case-evaluated on factors other than direct effects].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Lymphatic Metastasis; Male; Middle Aged; Mitomycin; Mitomycins; Neoplasm Recurrence, Local; Quality of Life; Stomach Neoplasms; Tegafur; Uracil | 1990 |
[Results of prophylactic intra-arterial infusion chemotherapy after hepatic resection in colorectal metastases].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorouracil; Hepatectomy; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Mitomycin; Mitomycins; Neoplasm Recurrence, Local; Postoperative Care; Tegafur; Uracil | 1990 |
[Effects of combination chemotherapy with topical application of 5-FU ointment to mice's tongue and UFT].
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Liver; Male; Mice; Ointments; Tegafur; Tongue; Uracil | 1990 |
[Combination chemotherapy of human renal cell carcinoma in athymic nude mice with human lymphoblastoid interferon (HLBI) and UFT, 5-Fu].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Combined Modality Therapy; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Interferon Type I; Kidney Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Tegafur; Uracil | 1990 |
In vivo 19F NMR spectroscopy of the antimetabolite 5-fluorouracil and its analogues. An assessment of drug metabolism.
Topics: Animals; Antineoplastic Agents; beta-Alanine; Carcinoid Tumor; Female; Floxuridine; Fluorouracil; Infusions, Intravenous; Liver; Magnetic Resonance Spectroscopy; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Tegafur | 1990 |
[Chemotherapy with fluoropyrimidines for MOPC-104E plasmacytoma transplanted in mice with CCl4 induced chronic liver dysfunction].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Floxuridine; Fluorouracil; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Plasmacytoma; Tegafur; Uracil | 1990 |
High-performance liquid chromatography with chemiluminescence detection of serum levels of pre-column derivatized fluoropyrimidine compounds.
Topics: Chromatography, High Pressure Liquid; Coumarins; Floxuridine; Fluorine; Fluorouracil; Humans; Molecular Structure; Pyrimidines; Tegafur; Umbelliferones; Uridine | 1990 |
[Antitumor activity of UFT against murine renal cell carcinoma: a study on the suppression tumor metastases].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Drug Screening Assays, Antitumor; Female; Fluorouracil; Kidney Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Survival Rate; Tegafur; Uracil | 1990 |
[Studies on 5-FU concentration and thymidine phosphorylase activity in tissues of patients with colorectal cancer after SF-SP administration].
Topics: Colorectal Neoplasms; Combined Modality Therapy; Delayed-Action Preparations; Fluorouracil; Humans; Portal Vein; Tegafur; Thymidine Phosphorylase; Tissue Distribution | 1990 |
[Antineoplastic activity of combinations of cytostatics and dextran-ferrite administered to mice with leukemia P-388].
Topics: Animals; Antineoplastic Agents; Cisplatin; Cyclophosphamide; Dactinomycin; Daunorubicin; Doxorubicin; Drug Combinations; Fluorouracil; Iron-Dextran Complex; Leukemia P388; Melphalan; Methotrexate; Mice; Tegafur | 1990 |
[Studies on the composition and stability constant of inclusion complexes of beta-cyclodextrin with fluorouracil and ftorafur by NMR].
Topics: beta-Cyclodextrins; Cyclodextrins; Drug Carriers; Drug Combinations; Drug Stability; Fluorouracil; Magnetic Resonance Spectroscopy; Tegafur | 1990 |
[Transformation of ovarian yolk sac tumor to immature teratoma following chemotherapy].
Topics: Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Fluorouracil; Humans; Mesonephroma; Mitomycin; Mitomycins; Ovarian Neoplasms; Tegafur; Teratoma; Uracil | 1985 |
[Combined chemotherapy and radiotherapy in recurrent tumors of the head and neck region].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy Dosage; Tegafur; Uracil | 1987 |
[Plasma and tissue concentration of tegafur by a new soft capsule type suppository in colorectal carcinoma].
Topics: Aged; Aged, 80 and over; Capsules; Colorectal Neoplasms; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Suppositories; Tegafur; Tissue Distribution | 1989 |
[Long-term administration of tegafur in postoperative adjuvant chemotherapy in gastric cancer patients. Serial analysis of serum tegafur and 5-fluorouracil concentrations, and influence from PSK combination].
Topics: Adjuvants, Immunologic; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouracil; Gastrectomy; Humans; Male; Middle Aged; Proteoglycans; Stomach Neoplasms; Tegafur; Time Factors; Uracil | 1989 |
[Experimental study on the effect of UFT with concomitant radiotherapy of uterine cervical cancer].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Division; Cell Line; Combined Modality Therapy; DNA Polymerase II; Female; Fluorouracil; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Tegafur; Tumor Cells, Cultured; Uracil; Uterine Cervical Neoplasms | 1989 |
5-Fluorouracil and UFT-sensitive gastric carcinoma has a high level of thymidylate synthase.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Male; Mice; Mice, Inbred C3H; Stomach Neoplasms; Subrenal Capsule Assay; Tegafur; Thymidylate Synthase; Uracil | 1989 |
[Conservative treatment of malignant liver tumors].
Topics: Adult; Aged; Combined Modality Therapy; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Particle Accelerators; Radiotherapy Dosage; Tegafur | 1989 |
[The concentration of 5-fluorouracil in blood and tissues of the patients with carcinoma of the cervix after administration of UFT and 5-fluorouracil].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Middle Aged; Tegafur; Tissue Distribution; Uracil; Uterine Cervical Neoplasms | 1989 |
The uptake of anticancer drugs by tumor tissues and lymph node and the effectiveness of postoperative adjuvant chemotherapy on survival time.
Topics: Combined Modality Therapy; Fluorouracil; Humans; Lymph Nodes; Prognosis; Stomach Neoplasms; Tegafur; Time Factors | 1989 |
[Influence of OK-432 on intratumor 5-fluorouracil concentration in cases given UFT].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biological Products; Biotransformation; Colonic Neoplasms; Fluorouracil; Humans; Lymphatic Metastasis; Picibanil; Stomach Neoplasms; Tegafur; Tissue Distribution; Uracil | 1989 |
Pharmacokinetic modulation of plasma 5-fluorouracil concentrations to potentiate the antitumor activity of continuous venous infusion of 5-fluorouracil.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Circadian Rhythm; Drug Synergism; Fluorouracil; Infusions, Intravenous; Kinetics; Leukocyte Count; Pyridines; Rats; Sarcoma, Yoshida; Tegafur; Uracil | 1989 |
[Anti-tumor effect of fluoropyrimidines on human tumor cell lines transplanted in nude mice with CCl4-induced liver dysfunction].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carbon Tetrachloride; Cell Line; Colonic Neoplasms; Fluorouracil; Humans; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Stomach Neoplasms; Tegafur; Transplantation, Heterologous; Uracil | 1989 |
[Effect of uracil on the both reactions, 5-fluorouracil degradation into 2-fluoro-beta-alanine and 5-fluorouracil splitting from tegafur in human tumor].
Topics: Adenocarcinoma, Papillary; Alanine; beta-Alanine; Fluorouracil; Humans; Lung Neoplasms; Tegafur; Tumor Cells, Cultured; Uracil | 1989 |
Adjuvant effects of calmodulin antagonists on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur) and a mixture of ftorafur and uracil (UFT) in nude mice bearing human ovarian carcinomas.
Topics: Animals; Calmodulin; Carcinoma; Drug Combinations; Drug Synergism; Female; Fluorouracil; Mice; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Sulfonamides; Tegafur; Time Factors; Uracil | 1989 |
[Effect of cepharanthine on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207)--5-fluorouracil delivery into tumor tissue].
Topics: Alkaloids; Animals; Benzylisoquinolines; Drug Therapy, Combination; Fluorouracil; In Vitro Techniques; Male; Mice; Neoplasm Transplantation; Sarcoma 180; Tegafur; Tumor Cells, Cultured | 1989 |
Distributions of tegafur in tissues of gastric adenocarcinoma patients: tissue uptakes and concentrations in plasma after oral and rectal administrations.
Topics: Adenocarcinoma; Administration, Oral; Administration, Rectal; Adult; Aged; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Stomach; Stomach Neoplasms; Suppositories; Tablets, Enteric-Coated; Tegafur; Tissue Distribution | 1989 |
[Serum and tissue concentration of tegafur and 5-FU after administration of tegafur suppository in patients with lung cancer--correcting the influence of residual blood in the tissue].
Topics: Adult; Aged; Female; Fluorouracil; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Suppositories; Tegafur; Tissue Distribution | 1989 |
[Combination effect of UFT and gamma-irradiation against nude mice transplanted KB cells].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Gamma Rays; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mouth Neoplasms; Neoplasm Transplantation; Tegafur; Uracil | 1989 |
[Study on the concentrations of 5-fluorouracil (5-FU), tegafur (ET) and uracil in bile: comparison of UFT or FT].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile; Biliary Tract Neoplasms; Cholestasis; Female; Fluorouracil; Humans; Male; Middle Aged; Tegafur; Uracil | 1989 |
The discrepancy between immunocytochemical and biochemical assay of estrogen receptor in breast cancer patients treated by endocrine therapy.
Topics: Adrenalectomy; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Ovariectomy; Receptors, Estrogen; Tamoxifen; Tegafur | 1989 |
[The serum and tissue concentration of FT-207, 5'-DFUR and 5-FU in patients with breast cancer by preoperative administration of UFT and 5'-DFUR].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Floxuridine; Fluorouracil; Humans; Lymph Nodes; Preoperative Care; Tegafur; Tissue Distribution; Uracil | 1989 |
Therapy of advanced gastric carcinoma. The Georgetown-Lombardi Cancer Center experience.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Doxorubicin; Fluorouracil; Folic Acid Antagonists; Humans; Middle Aged; Mitomycin; Mitomycins; Prognosis; Remission Induction; Stomach Neoplasms; Streptozocin; Tegafur; Triazines | 1989 |
[Level of inhibition of thymidylate synthase activity and 5-fluorouracil in tumor tissues after administration of UFT or tegafur].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Mice; Mice, Nude; Specific Pathogen-Free Organisms; Tegafur; Thymidylate Synthase; Uracil; Uterine Neoplasms | 1989 |
[Study on the pharmacokinetics of UFT in patients with hepatocellular carcinoma associated with cirrhosis].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Female; Fluorouracil; Humans; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Tegafur; Thymidylate Synthase; Uracil | 1989 |
[Preoperative chemotherapy for head and neck cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Maxillary Neoplasms; Mouth Neoplasms; Peplomycin; Pharyngeal Neoplasms; Preoperative Care; Tegafur; Uracil | 1985 |
[5-Fluorouracil, tegafur, and uracil concentrations in serum and tissue of the patients with hepatocellular carcinoma after UFT administration].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Drug Combinations; Fluorouracil; Humans; Liver Neoplasms; Tegafur; Uracil | 1987 |
[Cancer chemotherapy of scirrhous type gastric cancer and evaluation of chemotherapeutic efficacy].
Topics: Adenocarcinoma, Scirrhous; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fluorouracil; Humans; Injections, Intravenous; Mitomycin; Mitomycins; Radiography; Stomach Neoplasms; Tegafur; Uracil | 1988 |
[Therapeutic treatment of Borrmann type 4 (scirrhous) gastric cancer-chemotherapy and histopathological studies].
Topics: Adenocarcinoma, Scirrhous; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Gastric Mucosa; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Stomach; Stomach Neoplasms; Tegafur; Uracil | 1988 |
Radiation therapy for advanced gastric cancer.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adenocarcinoma, Papillary; Adult; Aged; Aged, 80 and over; Cobalt Radioisotopes; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Particle Accelerators; Radioisotope Teletherapy; Retrospective Studies; Stomach Neoplasms; Tegafur | 1988 |
[Hormone therapy of breast cancer-its role in the treatment of breast cancer].
Topics: Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Postoperative Care; Receptors, Estrogen; Tamoxifen; Tegafur | 1985 |
The therapeutic effects of orally administered 5'-deoxy-5-fluorouridine, 1-(2-tetrahydrofuryl)-5-fluorouracil and 5-fluorouracil on experimental murine tumors.
Topics: Animals; Antineoplastic Agents; Floxuridine; Fluorouracil; Leukemia L1210; Mice; Neoplasms, Experimental; Tegafur | 1985 |
[Observation on the curative effect postoperatively of late gastric cancer by the fu zheng anti-cancer method combined with chemotherapy].
Topics: Adenocarcinoma; Adult; Aged; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Middle Aged; Plant Extracts; Plants, Medicinal; Postoperative Care; Stomach Neoplasms; Tegafur | 1985 |
[Effects of derivatives of Ara-C, 5-fluorouracil and nitrosourea against intracerebral implanted L1210 leukemia].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Cytarabine; Fluorouracil; Leukemia L1210; Mice; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Streptozocin; Tegafur; Uracil | 1987 |
[Combination chemotherapy with 3 or 4 drugs on human breast and gastrointestinal cancer xenografts in nude mice (II)].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Colonic Neoplasms; Cyclophosphamide; Doxorubicin; Female; Floxuridine; Fluorouracil; Humans; Methotrexate; Mice; Mice, Nude; Mitomycin; Mitomycins; Neoplasm Transplantation; Stomach Neoplasms; Tegafur; Vindesine | 1987 |
[BOF-A1 and BOF-A2, new 5-FU degradation-inhibitory agents].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Floxuridine; Fluorouracil; Liver; Mice; Pyridines; Pyrimidines; Rats; Sarcoma 180; Sarcoma, Experimental; Sarcoma, Yoshida; Tegafur; Uracil | 1987 |
[Comparative studies on the antitumor activity of the fluorinated pyrimidines 5'-DFUR, tegafur, UFT and FUra on various murine tumors].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Floxuridine; Fluorouracil; Leukemia P388; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Neoplasms, Experimental; Sarcoma 180; Tegafur; Uracil | 1988 |
The antiproliferative effects of fluoropyrimidine derivatives against human tumor xenografts in a subrenal capsule assay.
Topics: Animals; Antineoplastic Agents; Body Weight; Cell Division; Colorectal Neoplasms; Floxuridine; Fluorouracil; Humans; Male; Mice; Mice, Nude; Stomach Neoplasms; Subrenal Capsule Assay; Tegafur; Transplantation, Heterologous | 1988 |
Natural history of hepatocellular carcinoma and prognosis in relation to treatment. Study of 850 patients.
Topics: Adolescent; Adult; Aged; Carcinoma, Hepatocellular; Embolization, Therapeutic; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Neoplasm Staging; Prognosis; Retrospective Studies; Tegafur; Time Factors | 1985 |
[Blood level of 5-fluorouracil (5-FU) by oral administration of 1-hexylcarbamoyl-5-fluorouracil (HCFU) and tegafur in patients with hepatocellular carcinoma].
Topics: Administration, Oral; Adult; Antineoplastic Agents; Carcinoma, Hepatocellular; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Tegafur | 1985 |
[FT, 5-FU and uracil concentrations of the blood, bile and tissue of hepatoma with liver cirrhosis after oral administration of UFT].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Bile; Carcinoma, Hepatocellular; Female; Fluorouracil; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Tegafur; Uracil | 1987 |
Hepatic conversion of 1-(tetrahydro-2-furanyl)-5-fluorouracil into 5-fluorouracil in patients with hepatocellular carcinoma.
Topics: Aged; Carcinoma, Hepatocellular; Drug Therapy, Computer-Assisted; Fluorouracil; Humans; In Vitro Techniques; Injections, Intravenous; Kinetics; Liver Cirrhosis; Liver Neoplasms; Male; Microsomes, Liver; Middle Aged; Tegafur | 1987 |
[UFT in the treatment of primary lung cancer--5-FU concentration in the tissue and side effects].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Middle Aged; Tegafur; Uracil | 1987 |
N1-(2 tetrahydrofuryl)-5-fluorouracil (FT-207) in the postoperative adjuvant chemotherapy of gastric cancer. Delivery of a fat-emulsified agent to the lymph.
Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Fat Emulsions, Intravenous; Fluorouracil; Humans; Lymph; Male; Middle Aged; Postoperative Care; Stomach Neoplasms; Tegafur; Thoracic Duct | 1986 |
Reversible leukoencephalopathy caused by 5-fluorouracil derivatives, presenting as akinetic mutism.
Topics: Anal Gland Neoplasms; Animals; Breast Neoplasms; Carcinoma; Female; Fluorouracil; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Movement Disorders; Mutism; Tegafur; Tomography, X-Ray Computed | 1986 |
[5-FU, FT-207 and uracil concentrations in the serum and tissues of patients with cervical cancer after UFT oral administration].
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Humans; Kinetics; Middle Aged; Ovary; Tegafur; Uracil; Uterine Cervical Neoplasms | 1986 |
[5-FU concentration in blood and tissue of patients with primary lung cancer after oral administration of UFT].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Tegafur; Uracil | 1986 |
[Combined effects of radiation and 5-FU derivatives].
Topics: Adenocarcinoma; Animals; Cell Division; Fluorouracil; Male; Mice; Radiotherapy Dosage; Tegafur | 1986 |
[Adjuvant therapy of gastric cancer in the literature from 1980-1984].
Topics: Antineoplastic Agents; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Humans; Mitomycin; Mitomycins; Neoplasm Staging; Postoperative Period; Stomach Neoplasms; Tegafur | 1986 |
[Study on the concentration of FT-207 and 5-FU in serum and tissues of bladder tumor and prostatic carcinoma].
Topics: Adult; Aged; Fluorouracil; Humans; Male; Middle Aged; Prostate; Prostatic Neoplasms; Suppositories; Tegafur; Urinary Bladder; Urinary Bladder Neoplasms | 1986 |
[The concentration in the tissue and antitumor effect of anticancer drug--assessment of breast cancer with UFT or FT-207].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Tegafur; Uracil | 1986 |
Potentiation of the chemotherapeutic action of tegafur against solid adenocarcinoma 755 by combination with L-cystine.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Carbon Radioisotopes; Cysteine; Cystine; Drug Synergism; Fluorouracil; Male; Mice; Mice, Inbred Strains; Tegafur | 1986 |
[Clinical study of THP-adriamycin in patients with advanced gastric cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms; Tegafur; Uracil | 1986 |
[5-FU concentration in the blood and tissue of patients with gastric and colorectal cancer after administration of UFT or tegafur].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Male; Rats; Rats, Inbred Strains; Rectal Neoplasms; Stomach Neoplasms; Tegafur; Uracil | 1986 |
[Effects of krestin (PSK) on drug-metabolizing enzymes with special reference to the activation of FT-207].
Topics: Aminopyrine; Animals; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Fluorouracil; Mice; Mice, Inbred ICR; Microsomes, Liver; Propionibacterium acnes; Proteoglycans; Sarcoma 180; Tegafur | 1986 |
[Influence of OK-432 on the concentration of active substance of fluoropyrimidine carcinostatics in the living body].
Topics: Biological Products; Fluorouracil; Head and Neck Neoplasms; Humans; Picibanil; Tegafur | 1986 |
[Comparison of continuous venous infusion of 5-FU and FT-207 under total parenteral nutrition].
Topics: Animals; Fluorouracil; Infusions, Intravenous; Male; Parenteral Nutrition, Total; Rats; Rats, Inbred Strains; Sarcoma, Yoshida; Tegafur | 1986 |
[In vitro effects of 5-FU on gynecologic malignant tumor cell lines].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cell Line; Cells, Cultured; Colony-Forming Units Assay; Female; Fluorouracil; Humans; Ovarian Neoplasms; Tegafur; Tumor Stem Cell Assay; Uracil; Uterine Cervical Neoplasms | 1986 |
[Serum and tissue concentrations of UFT in patients with lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Lung; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Tegafur; Uracil | 1986 |
[Metabolism of tegafur in partial hepatectomized rats].
Topics: Animals; Cytochrome P-450 Enzyme System; Fluorouracil; Hepatectomy; Liver; Liver Regeneration; Male; Rats; Rats, Inbred Strains; Tegafur | 1986 |
[Studies on oral-adjuvant chemotherapy of uterine cervical cancer after surgical treatment].
Topics: Adenocarcinoma; Administration, Oral; Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Neoplasm Recurrence, Local; Tegafur; Tumor Stem Cell Assay; Uterine Cervical Neoplasms | 1986 |
Prognostic factors in metastatic carcinoma of unknown primary.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Cyclophosphamide; Dacarbazine; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Neoplasms, Unknown Primary; Prognosis; Skin Neoplasms; Statistics as Topic; Tegafur; Vincristine | 1986 |
[Effects of intravenous feeding on adjuvant chemotherapy--an experimental study on the distribution of 5-FU after injection of tegafur (1)].
Topics: Animals; Fluorouracil; Liver; Lung Neoplasms; Male; Parenteral Nutrition; Rats; Rats, Inbred Strains; Tegafur; Tissue Distribution | 1987 |
[Determination of the individual sensitivity of human stomach cancer cells to fluoropyrimidines by the cytomorphological criteria of heterotransplants in diffusion chambers].
Topics: Adenocarcinoma; Animals; Carcinoma; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Male; Neoplasm Transplantation; Pyrimidines; Rats; Rats, Inbred Strains; Stomach Neoplasms; Tegafur; Time Factors; Transplantation, Heterologous; Tumor Stem Cell Assay | 1986 |
[Chemosensitivity testing for 5-FU and 5-FU derivatives using subrenal capsule assay].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colony-Forming Units Assay; Fluorouracil; Humans; Lung Neoplasms; Stomach Neoplasms; Tegafur; Tumor Stem Cell Assay; Uracil | 1987 |
[Concentration of 5-FU and tegafur in the ascites fluid in patients with peritonitis carcinomatosa after UFT oral administration].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Fluorouracil; Gastrointestinal Neoplasms; Humans; Peritonitis; Tegafur; Uracil | 1987 |
Anticancer drug distribution in lymph and blood during adjuvant chemotherapy after surgery for gastric carcinoma. A study with a combined preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil and uracil.
Topics: Combined Modality Therapy; Drug Combinations; Fluorouracil; Humans; Lymph; Male; Metabolic Clearance Rate; Middle Aged; Stomach Neoplasms; Tablets, Enteric-Coated; Tegafur; Uracil | 1987 |
Intestinal absorption characteristics of 5-fluorouracil, ftorafur and 6-mercaptopurine in rats.
Topics: Animals; Fluorouracil; In Vitro Techniques; Intestinal Absorption; Kinetics; Male; Mercaptopurine; Rats; Rats, Inbred Strains; Tegafur | 1986 |
[Studies on 5-FU concentration in serum and bladder tumor tissue after oral administration of UFT].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Male; Middle Aged; Mucous Membrane; Tegafur; Uracil; Urinary Bladder; Urinary Bladder Neoplasms | 1986 |
[The effect of gastrectomy on serum 5-FU concentrations of patients administered UFT per os].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Gastrectomy; Humans; Male; Middle Aged; Postoperative Period; Stomach Neoplasms; Tegafur; Uracil | 1987 |
[Improved quality of life in a patient with Borrmann type 4 gastric cancer treated with combination chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Picibanil; Prognosis; Quality of Life; Stomach Neoplasms; Tegafur; Uracil | 1987 |
[FO-152].
Topics: Absorption; Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Dogs; Drug Evaluation; Female; Fluorouracil; Humans; Leukemia L1210; Lung Neoplasms; Male; Mice; Stomach Neoplasms; Tegafur; Uridine | 1987 |
[A study on UFT concentration in tissues and serum of patients with malignant gynecologic tumors following oral administration].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Genital Neoplasms, Female; Humans; Lymph Nodes; Ovary; Tegafur; Uracil; Uterus | 1987 |
[Results of combined radiochemotherapy of intracranial ependymoma].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cerebral Ventricle Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Ependymoma; Female; Fluorouracil; Follow-Up Studies; Humans; Infant; Infant, Newborn; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Nitrosourea Compounds; Tegafur | 1987 |
[5-FU concentration in tumor tissue and the antitumor effect in patients with gastric cancer after oral administration of UFT].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms; Tegafur; Uracil | 1987 |
Enhancing effect of bromovinyldeoxyuridine on antitumor activity of 5-fluorouracil and ftorafur against adenocarcinoma 755 in mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Cysteine; Drug Evaluation, Preclinical; Drug Synergism; Fluorouracil; Male; Mice; Tegafur | 1987 |
[N1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) is metabolized and converted to 5-fluorouracil in tumor cells].
Topics: Animals; Cells, Cultured; DNA, Neoplasm; Fluorouracil; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Tegafur | 1987 |
[Serum concentration of 5-FU and tegafur (FT-207) after administration of tegafur (FT-207) suppository with the colostomy].
Topics: Adult; Aged; Colostomy; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Middle Aged; Rectal Neoplasms; Stomach Neoplasms; Suppositories; Tegafur | 1987 |
[Effects of intravenous alimentation on adjuvant chemotherapy--an experimental study on the distribution of 5-FU after injection of tegafur (2)].
Topics: Animals; Fluorouracil; Injections, Intravenous; Lung Neoplasms; Parenteral Nutrition, Total; Rats; Tegafur; Tissue Distribution | 1987 |
[The effect of tegafur suppository and glutathione in patients with gastric and colonic cancer with special reference to the histopathological anticancer effect].
Topics: Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Glutathione; Humans; Stomach Neoplasms; Suppositories; Tegafur | 1987 |
[Tegafur and 5-FU concentrations in cancerous and normal tissues in nude mice after oral administration of UFT].
Topics: Animals; Drug Combinations; Female; Fluorouracil; Kidney; Liver; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Tegafur; Time Factors; Tissue Distribution; Transplantation, Heterologous; Uracil; Urologic Neoplasms | 1987 |
[Human colorectal carcinoma is more sensitive to HCFU than 5-FU and tegafur in in vitro and in vivo drug sensitivity tests].
Topics: Animals; Colonic Neoplasms; Fluorouracil; Humans; Mice; Rectal Neoplasms; Subrenal Capsule Assay; Tegafur; Tumor Cells, Cultured | 1988 |
[Antitumor effect of UFT on human ovarian cancer grafted to nude mice and 5-FU concentration in tumor and normal tissues].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Tegafur; Tissue Distribution; Uracil | 1988 |
[Antitumor effect of intermittent oral administration of UFT against human rectal cancer xenografted in nude mice].
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Drug Administration Schedule; Fluorouracil; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Rectal Neoplasms; Tegafur; Uracil | 1988 |
[A case of recurrent sigmoid colon cancer successfully treated with 5-FU and UFT].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Lymphatic Metastasis; Middle Aged; Sigmoid Neoplasms; Tegafur; Uracil | 1988 |
[Clinical study on the effect of chemotherapy in the treatment of pancreatic cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Middle Aged; Pancreatic Neoplasms; Prognosis; Tegafur; Uracil | 1988 |
Sensitivity test for 5-fluorouracil and its analogues, 1-(2-tetrahydrofuryl)-5-fluorouracil, uracil/1-(2-tetrahydrofuryl)-5-fluorouracil (4:1) and 1-hexylcarbamoyl-5-fluorouracil, using the subrenal capsule assay.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Resistance; Fluorouracil; Gastrointestinal Neoplasms; Humans; Kidney; Male; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Subrenal Capsule Assay; Tegafur; Uracil | 1988 |
[Inhibitory effect of UFT on postoperative lung metastasis of mammary adenocarcinoma in SHR rats].
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Female; Fluorouracil; Lentinan; Lung Neoplasms; Mammary Neoplasms, Experimental; Rats; Rats, Inbred SHR; Tegafur; Uracil | 1988 |
[Effects of OK-432 on UFT activation].
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Biological Products; Fluorouracil; Humans; Liver Neoplasms, Experimental; Male; Middle Aged; Neoplasms; Picibanil; Rats; Rats, Inbred Strains; Tegafur; Uracil | 1988 |
[Experimental and clinical study of interactions between fluorinated pyrimidine derivatives and anticoagulants].
Topics: Animals; Anticoagulants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Fluorouracil; Humans; Lung Neoplasms; Neoplasm Transplantation; Pyrimidines; Rats; Rats, Inbred Strains; Tegafur; Ticlopidine; Uracil; Warfarin | 1988 |
[Uptake of anticancer drugs by target organs and the usefulness of adjuvant chemotherapy].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Fluorouracil; Gastrectomy; Humans; Lymph Nodes; Male; Middle Aged; Postoperative Period; Prognosis; Stomach Neoplasms; Tegafur | 1988 |
[Combined effects of interferon alpha-A/D with fluoropyrimidine derivatives in the subrenal capsule assay].
Topics: Animals; Colonic Neoplasms; Drug Synergism; Fluorouracil; Interferon Type I; Male; Mice; Mice, Nude; Neoplasm Transplantation; Stomach Neoplasms; Subrenal Capsule Assay; Tegafur | 1988 |
[The serum and tissue concentrations of tegafur, 5-fluorouracil and uracil in patients with gastric and colorectal cancers after oral administration of UFT].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Humans; Rectal Neoplasms; Stomach Neoplasms; Tegafur; Uracil | 1988 |
[MQF-FT and MQF-UFT in gallbladder and bile duct cancer].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Carbazilquinone; Drug Administration Schedule; Female; Fluorouracil; Gallbladder Neoplasms; Humans; Infusions, Intravenous; Male; Middle Aged; Mitomycin; Mitomycins; Picibanil; Tegafur; Uracil | 1988 |
[Complete response in a case of unresectable gastric cancer with a combination of tegafur, 5-fluorouracil and mitomycin C].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Liver Neoplasms; Male; Mitomycin; Mitomycins; Remission Induction; Stomach Neoplasms; Tegafur | 1988 |
[Inflammatory breast carcinoma--possibilities and results of surgical treatment and adjuvant chemotherapy, especially when done preoperatively].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Metastasis; Preoperative Care; Tegafur; Time Factors | 1988 |
Effect of PSK, a protein-bound polysaccharide from Coriolus versicolor, on drug-metabolizing enzymes in sarcoma-180 bearing and normal mice.
Topics: Adjuvants, Immunologic; Animals; Antibiotics, Antineoplastic; Female; Fluorouracil; Liver; Mice; Mice, Inbred ICR; Pharmaceutical Preparations; Propionibacterium acnes; Proteoglycans; Sarcoma 180; Tegafur | 1988 |
[Blood and tumor levels of tegafur, 5-fluorouracil, and uracil].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms; Tegafur; Uracil | 1988 |
[Pre- and post-operative adjuvant chemotherapy of colorectal cancer. Part 1. Drug concentration in tissues following UFT administration].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorouracil; Humans; Postoperative Period; Tegafur; Uracil | 1988 |
[Clinical studies of the treatment of bladder tumor and its effects--experience in 86 cases].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Picibanil; Prognosis; Tegafur; Uracil; Urinary Bladder Neoplasms | 1988 |
[Treatment of pancreatitis by electrophoresis of cytostatics].
Topics: Acute Disease; Adult; Aged; Chronic Disease; Female; Fluorouracil; Humans; Iontophoresis; Male; Middle Aged; Pancreatitis; Tegafur; Ultrasonic Therapy | 1988 |
UFT is more antineoplastic against gastric carcinoma than 5-fluorouracil, 1-(2-tetrahydrofuryl)-5-fluorouracil and 1-hexylcarbamoyl-5-fluorouracil.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Male; Mice; Stomach Neoplasms; Subrenal Capsule Assay; Tegafur; Uracil | 1988 |
[A case of variant angina induced by 5-fluorouracil and Tegafur].
Topics: Adenocarcinoma; Angina Pectoris, Variant; Coronary Vasospasm; Electrocardiography; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms; Tegafur | 1988 |
[Level of 5-fluorouracil in cancerous and normal tissues of nude mice bearing human endometrial carcinoma after administration of UFT coadministered with nicardipin].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Nicardipine; Tegafur; Transplantation, Heterologous; Uracil; Uterine Neoplasms | 1988 |
A mechanism for the potentiation of the cytotoxic effects of antimetabolites drugs (FT-207, 5FU) by hyperthermia.
Topics: Cell Line; Cell Survival; Colonic Neoplasms; Combined Modality Therapy; Cytosol; Fluorouracil; Hot Temperature; Humans; Membrane Potentials; Succinate Dehydrogenase; Tegafur; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1988 |
[Chemotherapy of pancreatic cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Pancreatic Neoplasms; Streptozocin; Tegafur | 1985 |
[Clinical study on the permeability of FT-207 and 5-FU in primary lung cancer].
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Cell Membrane Permeability; Female; Fluorouracil; Humans; Infusions, Parenteral; Lung; Lung Neoplasms; Male; Middle Aged; Permeability; Suppositories; Tegafur | 1985 |
[Intra-arterial infusion chemotherapy using a subcutaneously implanted silicone reservoir--with reference to the chemotherapy protocol].
Topics: Abdominal Neoplasms; Aged; Antineoplastic Combined Chemotherapy Protocols; Catheterization; Cytarabine; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Silicone Elastomers; Stomach Neoplasms; Tegafur; Uracil | 1985 |
[5-FU concentration in blood and tissue of patients with renal cell carcinoma after administration of UFT].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Fluorouracil; Humans; Kidney Neoplasms; Tegafur; Uracil | 1985 |
[A cooperative study of alternating immunochemotherapy with futraful and PSK (second report)--3-year survival rate].
Topics: Adjuvants, Immunologic; Administration, Oral; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Postoperative Care; Proteoglycans; Stomach Neoplasms; Tegafur | 1985 |
Phase I and pharmacologic study of oral ftorafur and X ray therapy in advanced gastrointestinal cancer.
Topics: Administration, Oral; Adult; Aged; Combined Modality Therapy; Drug Evaluation; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Tegafur | 1985 |
[Effect of intravenous administration of FT-207 for gastric cancer].
Topics: Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Parenteral; Lymph Nodes; Male; Stomach Neoplasms; Tegafur | 1985 |
[Influence of immunopotentiators on the activation of 5-FU derivatives].
Topics: Adjuvants, Immunologic; Animals; Biological Products; Cytochrome P-450 Enzyme System; Fluorouracil; In Vitro Techniques; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Picibanil; Proteoglycans; Rats; Rats, Inbred Strains; Tegafur | 1985 |
[A case of complete regression of gastric carcinoma and liver metastases by treatment with tegafur].
Topics: Adenocarcinoma; Aged; Fluorouracil; Humans; Liver Neoplasms; Male; Stomach Neoplasms; Tegafur | 1985 |
[Preoperative chemotherapy for advanced breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Mitomycin; Mitomycins; Preoperative Care; Tegafur | 1985 |
[Phase II study of sustained released granules of tegafur (SF-SP) on inoperable or recurrent gastric cancer].
Topics: Adenocarcinoma; Adult; Aged; Delayed-Action Preparations; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms; Tegafur | 1985 |
[Preoperative treatment with UFT for patients with ovarian malignant tumors].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Middle Aged; Ovarian Neoplasms; Ovary; Preoperative Care; Tegafur; Uracil | 1985 |
[Clinical study on concentration of FT-207 and 5-FU in serum, lymph nodes and tissues after rectal administration of FT-207 suppositories for malignant diseases of the liver, biliary tract and pancreas].
Topics: Biliary Tract Neoplasms; Fluorouracil; Humans; Liver Neoplasms; Lymph Nodes; Pancreatic Neoplasms; Preoperative Care; Rectum; Suppositories; Tegafur | 1985 |
[Level of 5-FU in cancerous and normal tissues of nude mice after oral administration of tegafur coadministered with uracil (UFT)].
Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Female; Fluorouracil; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Tegafur; Uracil; Uterine Neoplasms | 1985 |
[5-FU concentration in the tissues (tumor and lymph node) of breast cancer patients given preoperative administration of UFT and FT].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Female; Fluorouracil; Humans; Lymph Nodes; Preoperative Care; Tegafur; Uracil | 1985 |
[Thermotherapy for cancer of the urinary bladder in combination with tegafur suppository and picibanil--concentrations of tegafur in the serum and tissues in bladder carcinoma].
Topics: Adult; Aged; Biological Products; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Female; Fluorouracil; Humans; Hyperthermia, Induced; Male; Middle Aged; Picibanil; Suppositories; Tegafur; Urinary Bladder; Urinary Bladder Neoplasms | 1985 |
Cyclic combination chemotherapy in advanced adenocarcinoma of the lung: comparison of two FAM schedules.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Tegafur | 1985 |
[Metabolism of 1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) in human maxillary cancer (OKK) cells in culture].
Topics: Cell Division; Cells, Cultured; Chromatography, Thin Layer; Cytosol; Fluorouracil; Humans; Maxillary Neoplasms; Tegafur | 1985 |
Effects of a fluorinated pyrimidinedione anti-cancer drug, 5-fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione (FT), and related compounds on nigro-striatal dopaminergic neurons in the central nervous system.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Antineoplastic Agents; Corpus Striatum; Dopamine; Fluorouracil; Haloperidol; Homovanillic Acid; Male; Methyltyrosines; Motor Activity; Neurons; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Substantia Nigra; Tegafur; Time Factors; Uracil | 1985 |
Relevance of the pharmacology of oral tegafur to its use as a 5-FU pro-drug.
Topics: Administration, Oral; Fluorouracil; Gastrointestinal Neoplasms; Humans; Injections, Intravenous; Kinetics; Tegafur | 1985 |
Long-term survivors of colorectal cancer with unresectable hepatic metastases.
Topics: Administration, Oral; Aged; Carcinoembryonic Antigen; Colonic Neoplasms; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Rectal Neoplasms; Tegafur | 1985 |
[Evaluation of combined radiotherapy of gastric carcinoma].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Middle Aged; Prognosis; Radiotherapy, High-Energy; Stomach Neoplasms; Tegafur | 1985 |
[Comparison of the concentration of HCFU, tegafur and 5-FU in the thoracic duct lymph after oral administration of HCFU and tegafur].
Topics: Administration, Oral; Female; Fluorouracil; Humans; Lymph; Middle Aged; Tegafur; Thoracic Duct | 1985 |
[A case of advanced male breast cancer treated effectively with estrogen].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Agents; Breast Neoplasms; Combined Modality Therapy; Diethylstilbestrol; Drug Administration Schedule; Fluorouracil; Humans; Male; Middle Aged; Tegafur | 1985 |
[A case of advanced gastric cancer showing complete cure by immunochemotherapy with FT-207 and OK-432 confirmed by thorough histologic examination of total gastrectomy matter].
Topics: Adenocarcinoma; Biological Products; Female; Fluorouracil; Gastrectomy; Humans; Injections, Intradermal; Middle Aged; Picibanil; Stomach; Stomach Neoplasms; Suppositories; Tegafur | 1985 |
[Chemotherapy with FT-207 suppository (Futraful Supo) in head and neck cancer--cooperative studies by six medical schools in Kanagawa Prefecture].
Topics: Adult; Aged; Anorexia; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nausea; Nose Neoplasms; Paranasal Sinus Neoplasms; Suppositories; Tegafur; Thyroid Neoplasms | 1985 |
[A study on plasma and tissue 5-FU concentrations in patients with cervical cancer treated with UFT].
Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Tegafur; Uracil; Uterine Cervical Neoplasms | 1985 |
[Comparison between FT-207 and 5-FU on intravesical absorption--experimental study on intravesical absorption in the dog].
Topics: Absorption; Animals; Dogs; Fluorouracil; Molecular Weight; Tegafur; Urinary Bladder | 1985 |
[Level of 5-FU in uterine cervical cancer tissue after oral administration of UFT].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cervix Uteri; Female; Fluorouracil; Humans; Middle Aged; Tegafur; Uracil; Uterine Cervical Neoplasms | 1985 |
[A case of long-term survival of liver metastasis of breast cancer successfully treated with chemotherapy and endocrine therapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Liver; Liver Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Methotrexate; Middle Aged; Tamoxifen; Tegafur | 1985 |
[5-FU concentration in tissues of gastric cancer patients with preoperative administration of UFT--especially in comparison with FT-207].
Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Levamisole; Stomach Neoplasms; Tegafur; Time Factors; Uracil | 1985 |
[A case of toxic leucoencephalopathy induced by 5FU derivatives].
Topics: Antineoplastic Agents; Brain; Brain Diseases; Breast Neoplasms; Female; Fluorouracil; Humans; Middle Aged; Tegafur | 1985 |
Diffusion of anti-tumor drugs through membranes from hydrophilic methacrylate gels.
Topics: Acrylates; Acrylic Resins; Antineoplastic Agents; Diffusion; Fluorouracil; Glycine; Membranes, Artificial; Mercaptopurine; Methacrylates; Polyhydroxyethyl Methacrylate; Purines; Sulfides; Tegafur; Valerates | 1974 |
Ftorafur therapy in acute pancreatitis.
Topics: Acute Disease; Adult; Aged; Amylases; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Middle Aged; Pancreatic Function Tests; Pancreatitis; Tegafur | 1984 |
Effects of 1,3-bis(tetrahydro-2-furanyl)-5-fluoro-2,4-pyrimidinedione (FD 1) on the central nervous system: (2) Effects on nigro-striatal dopaminergic neurons.
Topics: alpha-Methyltyrosine; Aminooxyacetic Acid; Animals; Antineoplastic Agents; Bicuculline; Corpus Striatum; Dopamine; Fluorouracil; Male; Methyltyrosines; Neurons; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Substantia Nigra; Tegafur; Tyrosine 3-Monooxygenase | 1981 |
Potentiation of the antitumor activity of tegafur in sarcoma 180-bearing mice by chlordiazepoxide, diazepam and oxazepam.
Topics: Animals; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Drug Synergism; Fluorouracil; Male; Mice; Oxazepam; Sarcoma 180; Tegafur | 1983 |
[FAR therapy in brain tumors--FT207-vitamin A-Radiation therapy (author's transl)].
Topics: Adolescent; Adult; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Drug Therapy, Combination; Female; Fluorouracil; Glioma; Humans; Infant; Male; Medulloblastoma; Middle Aged; Radiotherapy Dosage; Tegafur; Vitamin A | 1980 |
[Autoradiography studies of cell proliferation and the effect of cytostatic agents on the proliferation of normal and tumor cells].
Topics: Animals; Antineoplastic Agents; Autoradiography; Bleomycin; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Division; Fluorouracil; Jejunum; Mice; Rats; Tegafur; Thymidine; Vincristine | 1983 |
[Clinical evaluation of chemotherapeutic agents in the treatment of primary liver cancer].
Topics: Adult; Aged; alpha-Fetoproteins; Carcinoma, Hepatocellular; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Tegafur | 1982 |
Multidisciplinary treatment for esophageal carcinoma.
Topics: Adult; Age Factors; Aged; Bleomycin; Esophageal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Radiography; Tegafur | 1983 |
[Pharmacokinetics study of UFT in malignant brain tumor patients].
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Drug Combinations; Female; Fluorouracil; Glioma; Humans; Kinetics; Male; Middle Aged; Tegafur; Uracil | 1983 |
Chemotherapy in advanced urinary bladder cancer.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Doxorubicin; Drug Evaluation; Fluorouracil; Humans; Lymphatic Metastasis; Mitomycin; Mitomycins; Tegafur; Urinary Bladder Neoplasms | 1984 |
[Cancer of the maxillary antrum--a new multidisciplinary treatment containing neo-adjuvant chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Male; Maxillary Neoplasms; Middle Aged; Peplomycin; Tegafur; Uracil | 1984 |
Studies on the designing of chemotherapy for gastric cancer in man, based on the tumor tissue concentration of anticancer agents.
Topics: Antineoplastic Agents; Floxuridine; Fluorouracil; Gastric Mucosa; Humans; Stomach Neoplasms; Tegafur | 1982 |
[Pharmacological and pharmacodynamic aspects of cancer chemotherapy, with special reference to 5-fluorouracil and its derivatives].
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Floxuridine; Fluorouracil; Humans; Kinetics; Neoplasms; Tegafur; Uracil | 1982 |
[Immunochemotherapy with tegafur and schizophyllan for stomach cancer--report of 2 cases].
Topics: Aged; Drug Therapy, Combination; Female; Fluorouracil; Glycosaminoglycans; Humans; Male; Middle Aged; Sizofiran; Stomach Neoplasms; Tegafur | 1983 |
Occurrence of induced 6-thioguanine-resistant colonies in synchronized V79 cells after treatment with ftorafur. Effects of the S9 fraction.
Topics: Animals; Cell Cycle; Cell Line; Cricetinae; Drug Resistance; Floxuridine; Fluorouracil; Male; Microsomes, Liver; Mutation; Tegafur; Thioguanine | 1984 |
[Development of fluoropyrimidine derivatives].
Topics: Animals; DNA Replication; Floxuridine; Fluorouracil; Mice; Phosphorylation; Pyrimidine Nucleotides; Rats; Sarcoma, Experimental; Tegafur; Uracil | 1984 |
Pharmacokinetics of ftorafur after intravenous and oral administration.
Topics: Administration, Oral; Adult; Aged; Carcinoma, Hepatocellular; Female; Fluorouracil; Half-Life; Humans; Injections, Intravenous; Kinetics; Liver Function Tests; Liver Neoplasms; Male; Middle Aged; Tegafur | 1983 |
[5-FU concentration in brain tumors after co-administration of FT and uracil].
Topics: Brain Neoplasms; Drug Therapy, Combination; Fluorouracil; Glioblastoma; Humans; Meningeal Neoplasms; Meningioma; Tegafur; Uracil | 1983 |
[Clinical study on preoperative chemotherapy of primary breast cancer. 2--A comparative study of CPA + FT-207 (5-FUDS) and CPA + FT-207 (5-FUDS) + MMC].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Papillary; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Middle Aged; Mitomycin; Mitomycins; Preoperative Care; Tegafur | 1983 |
[Antineoplastic effect of UFT therapy (uracil-FT-207 combination therapy) on experimental pancreatic cancer transplanted in the pancreas and subcutaneous region].
Topics: Animals; Antineoplastic Agents; Carcinoma, Intraductal, Noninfiltrating; Cricetinae; Drug Therapy, Combination; Fluorouracil; Male; Mesocricetus; Neoplasm Transplantation; Neoplasms, Experimental; Pancreatic Neoplasms; Tegafur; Tissue Distribution; Transplantation, Homologous; Uracil | 1982 |
[Pre- and intra-operative chemotherapy using FT-207 suppositories--with special reference to lung cancer].
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Fluorouracil; Humans; Intraoperative Care; Lung Neoplasms; Preoperative Care; Suppositories; Tegafur | 1982 |
[Sequential changes in blood concentrations of tegafur and 5-FU during oral administration of fine granules of tegafur in patients with primary liver cancer].
Topics: Administration, Oral; Antineoplastic Agents; Carcinoma, Hepatocellular; Female; Fluorouracil; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Tegafur | 1982 |
[Cerebrospinal fluid distributions of systemically administered fluorinated pyrimidines].
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Ependymoma; Female; Fluorouracil; Glioblastoma; Humans; Male; Middle Aged; Tegafur | 1983 |
[Experimental studies on the enhancing effects of the combined therapy with tegafur and cytochrome C].
Topics: Animals; Carbon Tetrachloride Poisoning; Cytochrome c Group; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Lethal Dose 50; Male; Neoplasms, Experimental; Rats; Tegafur | 1983 |
[Clinical trial on the effect of tegafur (SF-SP)].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Capsules; Carcinoma, Intraductal, Noninfiltrating; Colonic Neoplasms; Delayed-Action Preparations; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Pancreatic Neoplasms; Stomach Neoplasms; Tegafur | 1984 |
Continuous intravenous administration of 1-(2-tetrahydrofuryl)-5-fluorouracil [FT] by intravenous hyperalimentation (IVH)--stability of FT in IVH solution and tumor levels of 5-fluorouracil (5-FU).
Topics: Colonic Neoplasms; Dose-Response Relationship, Drug; Fluorouracil; Humans; Parenteral Nutrition, Total; Rectal Neoplasms; Tegafur; Time Factors | 1983 |
Phase II study of ftorafur in previously untreated and treated patients with advanced colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms; Tegafur | 1983 |
[Single chemotherapy with 5-fluorouracil or ftorafur and combination chemotherapy with mitomycin C and 5-fluorouracil for inoperable elderly gastric cancers].
Topics: Aged; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Mitomycin; Mitomycins; Stomach Neoplasms; Tegafur | 1983 |
[Clinical study related to the concentration of Futraful suppository in organs].
Topics: Female; Fluorouracil; Humans; Jaw Neoplasms; Male; Mouth Neoplasms; Suppositories; Tegafur; Tissue Distribution | 1983 |
[Preparation of trophic ulcers of the lower limbs for autodermoplasty].
Topics: Administration, Topical; Bandages; Fluorouracil; Humans; Preoperative Care; Skin Transplantation; Surgical Flaps; Tegafur; Varicose Ulcer | 1983 |
[Evaluation of tissue concentrations of FT-207 and 5-FU in head and neck cancer].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Tegafur | 1983 |
[Evaluation of chemotherapy of breast cancer (2). Clinical evaluation of the blood and tissue concentrations of FT-207 following intrarectal administration].
Topics: Breast; Breast Neoplasms; Female; Fluorouracil; Humans; Lymph Nodes; Suppositories; Tegafur | 1983 |
[Combination chemotherapy of advanced gastric cancer with adriamycin, mitomycin C, and ftorafur].
Topics: Adenocarcinoma; Adult; Aged; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Stomach Neoplasms; Tegafur | 1983 |
[Case of Borrmann III stomach cancer effectively treated by UFT therapy (co-administration of uracil and futraful)].
Topics: Adenocarcinoma; Administration, Oral; Aged; Drug Therapy, Combination; Fluorouracil; Humans; Male; Stomach Neoplasms; Tegafur | 1983 |
[Conversion of 1-(2-tetrahydrofuryl-5-fluorouracil (FT-207) into 5-fluorouracil (5-FU) by human maxillary cancer cells (OKK) in culture].
Topics: Cells, Cultured; Fluorouracil; Humans; Maxillary Neoplasms; Tegafur | 1983 |
[Effect of extended chemotherapy using tegafur following surgery of stage III stomach cancer].
Topics: Aged; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Middle Aged; Postoperative Period; Stomach Neoplasms; Tegafur; Time Factors | 1983 |
[Enzymatic conversion of tegafur in human tumor tissue].
Topics: Adult; Female; Fluorouracil; Humans; In Vitro Techniques; Liver Neoplasms; Middle Aged; Stomach Neoplasms; Tegafur; Thymidine Phosphorylase | 1983 |
Metabolic activation of R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur) to 5-fluorouracil by soluble enzymes.
Topics: Animals; Biotransformation; Brain; Cytochrome P-450 Enzyme System; Cytosol; Fluorouracil; Intestine, Small; Kinetics; Liver; Male; Microsomes; Microsomes, Liver; Oxidation-Reduction; Rabbits; Tegafur | 1983 |
[Chemotherapy of gastric cancer patients with hepatic metastases].
Topics: Administration, Oral; Antibiotics, Antineoplastic; Fluorouracil; Humans; Liver Neoplasms; Mitomycin; Mitomycins; Neoplasm Metastasis; Prognosis; Stomach Neoplasms; Suppositories; Tegafur | 1983 |
[Effect of solcoseryl and combined therapy of solcoseryl and FT-207 for mice bearing meth-A tumor].
Topics: Actihaemyl; Animals; Drug Therapy, Combination; Fluorouracil; Methylcholanthrene; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; T-Lymphocytes; Tegafur; Tissue Extracts | 1983 |
[Adjuvant chemotherapy for aged patients with gastric carcinoma].
Topics: Aged; Antineoplastic Agents; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Mitomycin; Mitomycins; Proteoglycans; Stomach Neoplasms; Tegafur | 1983 |
[Study on the correlation between tissue uptake of anticancer agents and prognosis -- with special reference to Tegafur].
Topics: Adult; Aged; Antineoplastic Agents; Female; Fluorouracil; Humans; Lymph Nodes; Male; Middle Aged; Prognosis; Stomach Neoplasms; Tegafur | 1983 |
[Level of 5-FU in tumor tissues of the patients with head and neck malignant tumors after oral administration of UFT].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Fluorouracil; Head and Neck Neoplasms; Humans; Lymph Nodes; Tegafur; Uracil | 1983 |
Effects of ftorafur and 5-fluorouracil on the canine sinoatrial node.
Topics: Aminophylline; Animals; Calcium; Dogs; Female; Fluorouracil; Heart Atria; Heart Rate; Male; Myocardial Contraction; Pindolol; Sinoatrial Node; Stimulation, Chemical; Tegafur; Verapamil | 1983 |
Late results of postoperative long-term cancer chemotherapy for the gastric cancer patients subjected to curative resection.
Topics: Antibiotics, Antineoplastic; Carcinoma; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Neoplasm Staging; Postoperative Care; Proteoglycans; Stomach Neoplasms; Tegafur; Time Factors | 1983 |
[Experience of a combination chemotherapy consisting of 5-FU, MMC, and FT-207--side effects against kidney].
Topics: Aged; Drug Therapy, Combination; Fluorouracil; Humans; Kidney Diseases; Male; Mitomycin; Mitomycins; Stomach Neoplasms; Tegafur | 1983 |
Phase I evaluation of oral tegafur.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Blood Cell Count; Diarrhea; Dose-Response Relationship, Drug; Drug Evaluation; Female; Fluorouracil; Humans; Liver Diseases; Male; Middle Aged; Nausea; Skin Diseases; Tegafur; Vomiting | 1983 |
[UFT concentration in various tissues from cancer patients].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capsules; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Stomach Neoplasms; Tegafur; Tissue Distribution; Uracil | 1983 |
[Analysis of factors affecting clinical cancer chemotherapy].
Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Breast Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Pancreatic Neoplasms; Stomach Neoplasms; Tegafur | 1983 |
Studies to increase the antitumor activity of 1-(tetrahydro-2-furanyl)-5-fluorouracil and its metabolic aspects by combined administration with L-cysteine.
Topics: Absorption; Animals; Antineoplastic Agents; Biotransformation; Cysteine; Fluorouracil; Kinetics; Lethal Dose 50; Male; Mice; Microsomes, Liver; Rats; Rats, Inbred Strains; Tegafur | 1983 |
Simultaneous determination of tegafur and 5-fluorouracil in serum by GLC using nitrogen-sensitive detection.
Topics: Animals; Fluorouracil; Gas Chromatography-Mass Spectrometry; Injections, Intravenous; Kinetics; Male; Orotic Acid; Rabbits; Tegafur; Time Factors | 1983 |
[Chemotherapy of unresectable Borrmann's type IV stomach cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Fluorouracil; Humans; Mitomycin; Mitomycins; Picibanil; Stomach Neoplasms; Tegafur | 1983 |
[Clinical analysis on side effects of long-term oral administration of futraful to out-patients].
Topics: Administration, Oral; Alanine Transaminase; Aspartate Aminotransferases; Blood Proteins; Breast Neoplasms; Fluorouracil; Humans; L-Lactate Dehydrogenase; Outpatients; Serum Albumin; Stomach Neoplasms; Tegafur | 1983 |
[Pharmacokinetics and a phase I study of tegafur-uracil enterogranules in cancer patients].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Delayed-Action Preparations; Drug Combinations; Drug Evaluation; Female; Fluorouracil; Humans; Kinetics; Male; Middle Aged; Nausea; Neoplasms; Tegafur; Uracil | 1983 |
Duodenal adenoma with atypia following oral administration of tegafur.
Topics: Adenoma; Duodenal Neoplasms; Fluorouracil; Humans; Male; Middle Aged; Postoperative Care; Stomach Neoplasms; Tegafur | 1983 |
Enhancement of lymphatic transport of 1-(2-tetrahydrofuryl)-5-fluorouracil by polyacrylic acid aqueous gel and emulsion type suppositories in rats.
Topics: Acrylic Resins; Animals; Biological Availability; Emulsions; Fluorouracil; Gels; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hydrogen-Ion Concentration; Intestinal Absorption; Lymphatic System; Male; Rats; Rats, Inbred Strains; Suppositories; Tegafur | 1983 |
[Experimental study of the efficacy of ftorafur phonophoresis in simulated allergic uveitis].
Topics: Animals; Chinchilla; Fluorouracil; Hypersensitivity; Tegafur; Ultrasonics; Uveitis | 1983 |
[Kinetics and mechanism of ftorafur decomposition. 1. Determination of expiration dates of ftorafur injection solutions].
Topics: Drug Stability; Fluorouracil; Injections; Kinetics; Solutions; Tegafur; Time Factors | 1983 |
[Adjuvant chemotherapy for gastric cancer--relation between long-term administration of FT-207 and prognosis].
Topics: Adult; Aged; Female; Fluorouracil; Humans; Male; Middle Aged; Prognosis; Stomach Neoplasms; Tegafur | 1984 |
[Preoperative treatment of FT-207 suppository in cervical cancer-- serum and tumor tissue content of FT-207].
Topics: Cervix Uteri; Female; Fluorouracil; Humans; Suppositories; Tegafur; Uterine Cervical Neoplasms | 1984 |
[Cooperative phase II study of spansule tegafur (SF-SP)].
Topics: Administration, Oral; Aged; Breast Neoplasms; Capsules; Colonic Neoplasms; Delayed-Action Preparations; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Rectal Neoplasms; Stomach Neoplasms; Tegafur | 1984 |
[Long-term maintenance chemotherapy for pseudomyxoma peritonei of ovarian origin].
Topics: Aged; Cyclophosphamide; Female; Fluorouracil; Humans; Hysterectomy; Middle Aged; Neoplasm Seeding; Ovarian Neoplasms; Peritoneal Neoplasms; Reoperation; Tegafur | 1984 |
Phase I-II studies of oral tegafur (ftorafur).
Topics: Administration, Oral; Bone Marrow; Breast Neoplasms; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Evaluation; Fluorouracil; Humans; Leukopenia; Nausea; Neoplasms; Rectal Neoplasms; Tegafur; Vomiting | 1983 |
[Effective cases of advanced endometrial and recurrent ovarian cancers treated with oral administration of UFT].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Drug Combinations; Female; Fluorouracil; Humans; Lymphatic Metastasis; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Tegafur; Uracil; Uterine Neoplasms | 1984 |
Plasma levels of tegafur following implantation of polycarbonate pellets containing tegafur or FD-1 into rats.
Topics: Animals; Drug Implants; Fluorouracil; Male; Rats; Rats, Inbred Strains; Tegafur | 1983 |
[Clinical studies of kallidinogenase in combined chemotherapy for cervical cancer].
Topics: Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Kallikreins; Tegafur; Uterine Cervical Neoplasms | 1983 |
Effect of coadministration of uracil on the toxicity of tegafur.
Topics: Animals; beta-Alanine; Cats; Dogs; Female; Fluorouracil; Heart Diseases; Lethal Dose 50; Male; Mice; Nervous System Diseases; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Tegafur; Uracil | 1984 |
Phase II study of orally and rectally administered Tegafur in liver metastases from gastric carcinoma.
Topics: Administration, Oral; Adult; Aged; Drug Evaluation; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Rectum; Stomach Neoplasms; Tegafur; Thrombocytopenia | 1984 |
Prophylactic long-term treatment of bladder tumors with oral chemotherapy (tegafur).
Topics: Actuarial Analysis; Administration, Oral; Adult; Aged; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Tegafur; Time Factors; Urinary Bladder Neoplasms | 1984 |
[Chemical modification of anticancer agents from viewpoints of their pharmacokinetics].
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cytarabine; Doxorubicin; Fibrosarcoma; Fluorouracil; Kinetics; Mice; Mitomycin; Mitomycins; Rabbits; Sarcoma, Experimental; Tegafur | 1984 |
[Regulation of enzyme activities involved in pyrimidine synthesis and its application to cancer chemotherapy].
Topics: Administration, Oral; Animals; Deoxyuridine; Dihydrouracil Dehydrogenase (NAD+); DNA, Neoplasm; Drug Synergism; Fluorouracil; Neoplasms, Experimental; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Pentosyltransferases; Phosphorylation; Pyrimidines; Sarcoma, Yoshida; Tegafur; Thymidine; Thymine; Uracil; Uridine | 1984 |
[Clinical application of tegafur suppositories for bladder tumor].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Fluorouracil; Humans; Male; Middle Aged; Papilloma; Suppositories; Tegafur; Urinary Bladder Neoplasms | 1983 |
Blepharospasm associated with tegafur combination chemotherapy.
Topics: Antineoplastic Agents; Blepharospasm; Drug Therapy, Combination; Eyelid Diseases; Female; Fluorouracil; Humans; Middle Aged; Tegafur | 1984 |
[Pharmacokinetics of FT-207 rectum suppository in squamous cell carcinoma of the uterine cervix. (I) Pharmacokinetics in single administration at a dose of 1 gram].
Topics: Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Kinetics; Rectum; Suppositories; Tegafur; Uterine Cervical Neoplasms; Uterus | 1984 |
[Pharmacokinetics of FT-207 rectum suppository in squamous cell carcinoma of the uterine cervix. (II) Pharmacokinetics in continuous administration at a daily dose of 1 gram].
Topics: Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Fluorouracil; Humans; Kinetics; Lymph Nodes; Rectum; Suppositories; Tegafur; Uterine Cervical Neoplasms; Uterus | 1984 |
[Intraperitoneal administration of FT-207 for mouse peritonitis carcinomatosa].
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Fluorouracil; Injections, Intraperitoneal; Macrophages; Mice; Microscopy, Electron, Scanning; Peritonitis; Tegafur | 1984 |
[FT-207 and 5-FU concentrations in brain tumor tissues, plasma and CSF after administration of FT-207 suppository].
Topics: Brain; Brain Neoplasms; Fluorouracil; Humans; Rectum; Suppositories; Tegafur | 1984 |
[Studies on the mechanism of antitumor activity of 5-FU and its derivatives--relationship between the inhibition of tumor growth and the inhibition of thymidylate synthetase in vivo].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Division; DNA, Neoplasm; Drug Combinations; Fluorouracil; Male; Methyltransferases; Mice; Sarcoma 180; Tegafur; Thymidylate Synthase; Uracil | 1984 |
[The case studies on oral administration of tegafur encapsulated with slow releasing granule (SF-SP) for three rectal patients].
Topics: Adenocarcinoma; Administration, Oral; Aged; Capsules; Delayed-Action Preparations; Female; Fluorouracil; Humans; Male; Middle Aged; Rectal Neoplasms; Tegafur | 1984 |
[Effects of long-term administration of Tegafur on patients with relapsing advanced carcinoma (stage D) of the prostate].
Topics: Aged; Estrogens; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prostatic Neoplasms; Tegafur | 1983 |
[Combination chemotherapy of CIS-diamminedichloroplatinum (II) and fluoropyrimidine derivatives for advanced gastric cancer: a preliminary report].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms; Tegafur | 1984 |
Combination of hepatic arterial infusion and systemic chemotherapy for gastric cancer with synchronous hepatic metastases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Prognosis; Proteoglycans; Stomach Neoplasms; Tegafur | 1984 |
[Pharmacological compatibility of the antineoplastic drugs ftorafur and 5-fluorouracil with the psychotropic drugs aminazine and phenazepam (an experimental study)].
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Chlorpromazine; Drug Interactions; Fluorouracil; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Neoplasms, Experimental; Rats; Tegafur | 1984 |
[Cooperative phase II study of releasing tegafur (SF-SP) against advanced digestive cancers].
Topics: Administration, Oral; Adult; Aged; Colonic Neoplasms; Delayed-Action Preparations; Digestive System Neoplasms; Drug Evaluation; Esophageal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Pancreatic Neoplasms; Stomach Neoplasms; Tegafur | 1984 |
[Chemotherapy of unresectable Borrmann type 4 gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Combinations; Fluorouracil; Humans; Mitomycin; Mitomycins; Nimustine; Nitrosourea Compounds; Picibanil; Proteoglycans; Stomach Neoplasms; Tegafur; Uracil | 1984 |
Combination chemoimmunotherapy for advanced gastric carcinoma.
Topics: Adjuvants, Immunologic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Immunotherapy; Male; Middle Aged; Mitomycin; Mitomycins; Stomach Neoplasms; Tegafur | 1984 |
[Experimental chemotherapy of human gastrointestinal and breast cancers in nude mice and its correlation to clinical effect].
Topics: Adenocarcinoma; Adult; Aged; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Drug Combinations; Female; Fluorouracil; Humans; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Transplantation; Rectal Neoplasms; Stomach Neoplasms; Tegafur; Uracil | 1984 |
Neuropathologic study on chronic neurotoxicity of 5-fluorouracil and its masked compounds in dogs.
Topics: Animals; Axons; Brain; Dogs; Female; Fluorouracil; Male; Microscopy, Electron; Myelin Sheath; Neuroglia; Neurons; Tegafur; Vacuoles | 1984 |
[Study on the concentration of FT-207 and 5-FU in serum, lymph nodes and tissues after administration of FT-207 suppositories].
Topics: Adult; Aged; Breast Neoplasms; Female; Fluorouracil; Humans; Lymph Nodes; Lymphoma, Non-Hodgkin; Male; Middle Aged; Rectal Neoplasms; Stomach Neoplasms; Suppositories; Tegafur | 1984 |
[Thermotherapy for cancer of the urinary bladder in combination with tegafur and picibanil--with special reference to the serum bladder and bladder cancer tissue concentrations of tegafur in a perfusion fluid].
Topics: Aged; Biological Products; Combined Modality Therapy; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hyperthermia, Induced; Male; Middle Aged; Picibanil; Tegafur; Urinary Bladder; Urinary Bladder Neoplasms | 1984 |
[Influence of PSK on the metabolism of FT-207].
Topics: Antibiotics, Antineoplastic; Fluorouracil; Humans; Proteoglycans; Stomach Neoplasms; Tegafur | 1984 |
[Antitumor effect of FU-O-G, new antitumor agent, following long term administration].
Topics: Animals; Antineoplastic Agents; Carbazilquinone; Drug Administration Schedule; Drug Synergism; Female; Fluorouracil; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Pyrimidine Nucleosides; Tegafur | 1984 |
Enhanced accumulation of 5-fluorouracil in human tumors in athymic mice by co-administration of Ftorafur and uracil.
Topics: Animals; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Tegafur; Time Factors; Transplantation, Heterologous; Uracil | 1984 |
[Maximum tolerated dose of tegafur in rats].
Topics: Administration, Oral; Animals; Body Weight; Drug Administration Schedule; Drug Tolerance; Fluorouracil; Kidney; Liver; Lung; Male; Necrosis; Organ Size; Rats; Rats, Inbred Strains; Tegafur | 1984 |
[Pharmacokinetics of vaginal suppository FT-207 in uterine cervical cancer and radiation therapy].
Topics: Combined Modality Therapy; Female; Fluorouracil; Humans; Kinetics; Middle Aged; Suppositories; Tegafur; Uterine Cervical Neoplasms | 1984 |
[Pharmacokinetics of fluoropyrimidines].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich Tumor; Fluorouracil; Humans; Infusions, Parenteral; Kinetics; Mice; Neoplasms; Rabbits; Tegafur; Uracil | 1984 |
[Fluorinated pyrimidines--administration methods].
Topics: Drug Administration Schedule; Fluorouracil; Humans; Infusions, Parenteral; Neoplasms; Tegafur | 1984 |
[Comparative pharmacokinetic study between UFT and FT-207 suppo and phase II studies in gynecological malignancies].
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female; Fluorouracil; Humans; Kinetics; Middle Aged; Tegafur; Uracil; Uterine Cervical Neoplasms; Uterine Neoplasms | 1984 |
[10 years' use of ftorafur in tumor chemotherapy at the Robert Rössle Institute. A retrospective analysis from the clinical-toxologic point of view].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Lomustine; Male; Methotrexate; Middle Aged; Neoplasms; Retrospective Studies; Tamoxifen; Tegafur; Vinblastine; Vincristine | 1984 |
Fluorescence determination of 5-fluorouracil and 1-(tetrahydro-2-furanyl)-5-fluorouracil in blood serum by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Fluorouracil; Humans; Spectrometry, Fluorescence; Tegafur; Time Factors | 1984 |
Cytochrome P-450-dependent oxidative cleavage of 1-(tetrahydro-2-furanyl)-5-fluorouracil to 5-fluorouracil.
Topics: Animals; Cytochrome P-450 Enzyme System; Fluorouracil; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Oxidation-Reduction; Rabbits; Tegafur | 1984 |
[Chemotherapy of renal cell carcinoma. 3. Single-agent therapy with FT-207 or vinblastine].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Carcinoma, Renal Cell; Female; Fluorouracil; Humans; Injections, Intravenous; Kidney Neoplasms; Male; Middle Aged; Neoplasm Staging; Tegafur; Vinblastine | 1984 |
[Evaluation of tegafur encapsulated with slow-releasing granules (SF-SP) for patients with cancer of the digestive organs].
Topics: Administration, Oral; Adult; Aged; Capsules; Colonic Neoplasms; Delayed-Action Preparations; Drug Evaluation; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Stomach Neoplasms; Tegafur | 1984 |
[Adjuvant chemotherapy after surgery in advanced gastric cancer].
Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Middle Aged; Postoperative Care; Stomach Neoplasms; Tegafur | 1984 |
[Postoperative adjuvant chemotherapy with N1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) for gastric cancer patients. Influence of fat emulsification on lymphatic transport].
Topics: Adult; Aged; Fat Emulsions, Intravenous; Fluorouracil; Humans; Lymphatic System; Male; Middle Aged; Postoperative Period; Stomach Neoplasms; Tegafur | 1984 |
Enhancement of lymphatic transport of N1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) by water-in-oil emulsion in postoperative adjuvant chemotherapy for gastric cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Emulsions; Fluorouracil; Humans; Male; Middle Aged; Oils; Stomach Neoplasms; Tablets, Enteric-Coated; Tegafur | 1984 |
Photosensitivity from oral administration of a fluorouracil derivative (FT 207).
Topics: Aged; Antimetabolites, Antineoplastic; Fluorouracil; Humans; Male; Photosensitivity Disorders; Tegafur | 1984 |
Role of uridine phosphorylase for antitumor activity of 5'-deoxy-5-fluorouridine.
Topics: Animals; Biotransformation; Floxuridine; Fluorouracil; Leukemia L1210; Male; Mice; Pentosyltransferases; Sarcoma 180; Tegafur; Thymidine; Uridine; Uridine Phosphorylase | 1980 |
[Chemotherapy of pancreatic cancer is not yet generally recommended].
Topics: Antineoplastic Agents; Carmustine; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Mitomycins; Pancreatic Neoplasms; Streptozocin; Tegafur | 1980 |
Comparative studies on the immunosuppressive effect among 5'-deoxy-5-fluorouridine, ftorafur, and 5-fluorouracil.
Topics: Animals; Antibody Formation; Erythrocytes; Female; Floxuridine; Fluorouracil; Graft Rejection; Hypersensitivity, Delayed; Immunity, Cellular; Immunosuppressive Agents; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Tegafur | 1980 |
Tissue distribution of 5'-deoxy-5-fluorouridine and derived 5-fluorouracil in tumor-bearing mice and rats.
Topics: Animals; Carcinoma 256, Walker; Female; Floxuridine; Fluorouracil; Male; Mice; Rats; Sarcoma 180; Tegafur; Tissue Distribution | 1980 |
Differential effects of 5-fluorouracil analogs on humoral and cell-mediated responses in mice: augmentation of delayed hypersensitivity response against picryl chloride by 1,3-bis(tetrahydro-2-furanyl)-5-fluoro-2,4-pyrimidinedione (FD-1), a new anti-tumor
Topics: Animals; Antibody Formation; Drug Hypersensitivity; Fluorouracil; Graft Rejection; Hypersensitivity, Delayed; Immune Tolerance; Male; Mice; Picryl Chloride; Skin Transplantation; T-Lymphocytes, Regulatory; Tegafur; Transplantation, Homologous | 1980 |
Review of a new antimetabolic agent, 1,3-bis(tetrahydro-2-furanyl)-5-fluoro-2,4-pyrimidinedione (FD-1).
Topics: Adult; Aged; Animals; Antimetabolites, Antineoplastic; Delayed-Action Preparations; Dogs; Drug Evaluation; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Male; Mice; Middle Aged; Neoplasms; Neoplasms, Experimental; Rats; Tegafur; Vomiting | 1980 |
[Surgical method and combination chemotherapy in treating stage-III and IV ovarian cancer].
Topics: Altretamine; Antineoplastic Agents; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms; Ovary; Postoperative Care; Tegafur; Time Factors | 1980 |
Therapeutic effect dependent on timing of combination treatment with chemotherapy and allogeneic lymphoid cell transfer in rats.
Topics: Animals; Cell Transformation, Neoplastic; Cyclophosphamide; Drug Therapy, Combination; Fibrosarcoma; Fluorouracil; Immunization, Passive; Lymphocyte Transfusion; Rats; Rats, Inbred Strains; Tegafur; Time Factors; Transplantation, Homologous | 1980 |
Structure of two hydroxylated metabolites of ftorafur.
Topics: Chemical Phenomena; Chemistry, Physical; Fluorouracil; Hydroxylation; Stereoisomerism; Tegafur | 1980 |
Intensified cancer themotherapy by induction of hepatic drug-metabolizing enzymes as a trial for the treatment for stomach cancer.
Topics: Drug Therapy, Combination; Enzyme Induction; Fluorouracil; Humans; Liver; Mitomycins; Phenobarbital; Stomach Neoplasms; Tegafur | 1980 |
Effect of coadministration of thymine or thymidine on the antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil and 5-fluorouracil.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biodegradation, Environmental; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Liver; Male; Mice; Phosphorylation; Rats; Sarcoma 180; Sarcoma, Yoshida; Tegafur; Thymidine; Thymidine Phosphorylase; Thymine; Uracil; Uridine; Uridine Phosphorylase | 1980 |
Metabolism, antitumor activity, and acute toxicity of 5-fluoro-1,3-bis(tetrahydro-2-furanyl)-2,4-pyrimidinedione by oral administration to animals.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biotransformation; Chemical Phenomena; Chemistry; Fluorouracil; In Vitro Techniques; Male; Mass Spectrometry; Microsomes, Liver; Rats; Tegafur; Tissue Distribution | 1980 |
Quantitative determination of 1,3-bis(tetrahydro-2-furanyl)-5-fluoro-2,4-pyrimidinedione and its metabolites in visceral tissues by high-performance liquid chromatography and gas chromatography-mass fragmentography.
Topics: Animals; Chromatography, High Pressure Liquid; Fluorouracil; Gas Chromatography-Mass Spectrometry; Neoplasms; Rats; Tegafur | 1980 |
[Combined chemoimmunotherapy in stomach cancer and hematosarcoma].
Topics: Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Hemangiosarcoma; Humans; Immunotherapy; Neoplasm Recurrence, Local; Stomach Neoplasms; Tegafur; Time Factors | 1980 |
Activation of Ftorafue [R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil] to 5-fluorouracil and gamma-butyrolactone.
Topics: 4-Butyrolactone; Animals; Biotransformation; Cell-Free System; Chromatography, Gas; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Fluorouracil; Furans; Humans; Male; Metabolic Clearance Rate; Mice; Microsomes, Liver; Rabbits; Tegafur | 1980 |
[Drug exanthema caused by a new 5-fluorouracil derivative].
Topics: Chemical Phenomena; Chemistry; Exanthema; Female; Fluorouracil; Humans; Middle Aged; Tegafur | 1980 |
Identification of metabolites of 1-(tetrahydro-2-furanyl)-5-fluorouracil (FT-207) formed in vitro by rat liver microsomes.
Topics: Animals; Fluorouracil; In Vitro Techniques; Male; Microsomes, Liver; Rats; Tegafur | 1980 |
Clinical basis of chemotherapy for gastric cancer with uracil and 1-(2'-tetrahydrofuryl)-5-fluorouracil.
Topics: Female; Fluorouracil; Humans; In Vitro Techniques; Stomach Neoplasms; Tegafur; Time Factors; Uracil | 1980 |
[Studies in vivo and in vitro on the influence of 5-fluorouracil and n'-(2'-furanidyl)-5-fluorouracil on the walker carcinosarcoma 256 in the rat (author's transl)].
Topics: Animals; Carcinoma 256, Walker; Deoxyuridine; Dose-Response Relationship, Drug; Fluorouracil; Male; Rats; Tegafur | 1980 |
Relationship of chemotherapy on human cancer xenografts in nude mice to clinical response in donor patient.
Topics: Adult; Animals; Cytarabine; Drug Resistance; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Mice; Mice, Nude; Middle Aged; Mitomycins; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Tegafur; Transplantation, Heterologous | 1980 |
Altered pharmacodynamics of 1-(2-tetrahydrofuryl)-5-fluorouracil by pretreatment of rats with phenobarbital, indomethacin, diclofenac sodium and carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Diclofenac; Female; Fluorouracil; Indomethacin; Microsomes, Liver; Phenobarbital; Phenylacetates; Rats; Tegafur; Time Factors | 1980 |
Chemoprevention of development of colonic adenomatosis and carcinomatosis with 5-fluorouracil and ftorafur on animal model.
Topics: Adenoma; Animals; Carcinoma; Colon; Colonic Neoplasms; Female; Fluorouracil; Methylnitrosourea; Neoplasms, Experimental; Rats; Tegafur | 1980 |
Effects on 1,3-bis(tetrahydro-2-furanyl)-5-fluoro-2,4-pyrimidinedione(FD-1) on the central nervous system: 1. Effects on monoamines in the brain.
Topics: Acetylcholine; Animals; Antineoplastic Agents; Biogenic Amines; Brain Chemistry; Corpus Striatum; Fluorouracil; Hydroxybutyrates; Male; Rats; Tegafur; Time Factors | 1980 |
[Induced chromosome aberrations in multiple primary neoplasms].
Topics: Adult; Chromosome Aberrations; Female; Fluorouracil; Humans; In Vitro Techniques; Lymphocytes; Male; Middle Aged; Neoplasms, Multiple Primary; Tegafur | 1980 |
High-pressure liquid chromatographic determination of ftorafur [1-(tetrahydro-2-furanyl)-5-fluorouracil] and GLC-mass spectrometric determination of 5-fluorouracil and uracil in biological materials after oral administration of uracil plus ftorafur.
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Fluorouracil; Gas Chromatography-Mass Spectrometry; Male; Neoplasms, Experimental; Rats; Tegafur; Uracil | 1980 |
Effect of normal allogeneic lymphoid cell transfer in combination with chemotherapy on a transplantable tumor in rats.
Topics: Animals; Cyclophosphamide; Drug Therapy, Combination; Fibrosarcoma; Fluorouracil; Immunotherapy; Lymphocyte Transfusion; Rats; Sarcoma, Experimental; Tegafur; Time Factors; Transplantation, Homologous | 1980 |
A review of the United States clinical experience of the fluoropyrimidine, ftorafur (NSC-148958).
Topics: Administration, Oral; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intravenous; Neoplasms; Tegafur | 1980 |
Determination of 5-fluorouracil and pyrimidine bases in plasma by gas chromatography-chemical ionization-mass fragmentography.
Topics: Cytosine; Fluorouracil; Gas Chromatography-Mass Spectrometry; Humans; Ions; Pyrimidines; Tegafur; Thymine; Uracil | 1980 |
Comparing cell kinetic studies of the effect of ftorafur and 5-fluorouracil on the L 1210 ascites tumor.
Topics: Animals; Cell Division; Female; Fluorouracil; Kinetics; Leukemia L1210; Mice; Mitosis; Neoplasm Transplantation; Tegafur; Thymidine; Transplantation, Homologous; Uridine | 1981 |
Clastogenic effects of ftorafur. II. Cytogenetic analyses of bone marrow in mice.
Topics: Animals; Bone Marrow; Carcinogens; Chromosome Aberrations; Chromosomes; Dose-Response Relationship, Drug; Fluorouracil; Mice; Mice, Inbred C57BL; Mutagens; Tegafur; Time Factors | 1981 |
Toxicologic and therapeutic examinations with ftorafur in different mouse strains.
Topics: Animals; Female; Fluorouracil; Male; Mice; Mice, Nude; Neoplasms, Experimental; Sex Factors; Tegafur | 1981 |
[Chemo-endocrine therapy for advanced breast cancer--a combined treatment with tamoxifen and FT 207-- (author's transl)].
Topics: Breast Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Tamoxifen; Tegafur | 1981 |
[ACF combination consisting of adriamycin, cyclophosphamide and oral futraful for recurrent advanced breast cancer (author's transl)].
Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Middle Aged; Neoplasm Recurrence, Local; Tegafur | 1981 |
[Educational lecture of cancer chemotherapy: with references to stomach cancer (author's transl)].
Topics: Antineoplastic Agents; Drug Therapy, Combination; Fluorouracil; Humans; Stomach Neoplasms; Tegafur | 1981 |
Studies on the metabolism of 1-(2-tetrahydrofuryl)-5-fluorouracil and uracil co-administered orally to tumor-bearing rats.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Drug Combinations; Fluorouracil; Intestinal Absorption; Neoplasms, Experimental; Rats; Tegafur; Uracil | 1980 |
Comparative efficacy of antitumor treatment for liver metastases from colorectal cancer.
Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Rectal Neoplasms; Retrospective Studies; Tegafur | 1981 |
Antitumor activity of methyl (5-fluoro-1H-2-oxo-4-pyrimidinyl beta-D-glucopyranosid)uronate against various experimental tumors.
Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma 256, Walker; Female; Fluorouracil; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Pyrimidine Nucleosides; Rats; Tegafur; Time Factors | 1981 |
Clastogenicity and sister chromatid exchange induction by ftorafur.
Topics: Animals; Burkitt Lymphoma; Cell Line; Chromosomes; Chromosomes, Human; Cricetinae; Crossing Over, Genetic; Culture Techniques; Fibroblasts; Fluorouracil; Humans; Lymphocytes; Mammary Neoplasms, Experimental; Melanoma; Mutagens; Sister Chromatid Exchange; Tegafur | 1981 |
General pharmacological properties of UFT, a new type of anti-cancer agent consisting of 1-(2-tetrahydrofuryl)-5-fluorouracil (FT) and uracil. I: Pharmacological analysis of the combined effect of FT and uracil.
Topics: Analgesics; Animals; Anticonvulsants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Behavior, Animal; Body Temperature; Brain Chemistry; Digestive System; Dogs; Drug Combinations; Electroencephalography; Female; Fluorouracil; Guinea Pigs; Hemodynamics; Male; Mice; Postural Balance; Rabbits; Rats; Respiration; Tegafur; Uracil | 1981 |
Enzymatic formation of 5-fluorouracil from 1-(tetrahydro-2-furanyl)- 5-fluorouracil (tegafur) in human tumor tissues.
Topics: Biotransformation; Fluorouracil; Humans; In Vitro Techniques; Lung Neoplasms; Tegafur | 1981 |
Improved liquid chromatographic assay for serum fluorouracil concentrations in the presence of ftorafur.
Topics: Chromatography, Liquid; Drug Stability; Drug Storage; Fluorouracil; Gastrointestinal Neoplasms; Humans; Tegafur | 1981 |
High-dose therapy with ftorafur in gastrointestinal cancer.
Topics: Animals; Carcinoma, Ehrlich Tumor; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Male; Mice; Neoplasm Metastasis; Tegafur | 1981 |
Changes in toxic and antitumor properties of ftorafur by induction or inhibition of the microsomal enzymes activity.
Topics: Animals; Antineoplastic Agents; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Female; Fluorouracil; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; Phenobarbital; Tegafur | 1981 |
Correlation between the level of urinary D-glucaric acid and the degree of activation of masked compound (FT-207) in cancer patients.
Topics: Adult; Aged; Biotransformation; Cytochrome P-450 Enzyme System; Esophageal Neoplasms; Female; Fluorouracil; Glucaric Acid; Humans; Kinetics; Male; Microsomes, Liver; Middle Aged; Neoplasms; Pancreatic Neoplasms; Stomach Neoplasms; Sugar Acids; Tegafur | 1981 |
[A case of inoperable esophageal carcinoma responding to adriamycin and FT 207 suppository for more than one year (author's transl)].
Topics: Aged; Carcinoma, Squamous Cell; Doxorubicin; Drug Therapy, Combination; Esophageal Neoplasms; Female; Fluorouracil; Humans; Suppositories; Tegafur | 1981 |
[Conservative treatment of primary and recurrent malignant stomach neoplasms].
Topics: Adenocarcinoma; Adult; Aged; Carcinoma; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Male; Middle Aged; Radioisotope Teletherapy; Radiotherapy Dosage; Stomach Neoplasms; Tegafur | 1981 |
[Long-term chemotherapy with FT-207 for ovarian cancer (author's transl)].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Drug Administration Schedule; Female; Fluorouracil; Humans; Middle Aged; Ovarian Neoplasms; Tegafur; Time Factors | 1981 |
FQC combination chemotherapy for primary malignant ovarian tumor.
Topics: Azirines; Carbazilquinone; Cytarabine; Drug Therapy, Combination; Female; Fluorouracil; Humans; Ovarian Neoplasms; Tegafur | 1982 |
Stereoselective metabolism of ftorafur (R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil).
Topics: Animals; Biotransformation; Chromatography, Gas; Chromatography, High Pressure Liquid; Female; Fluorouracil; Hydroxylation; Liver; Mice; Microsomes, Liver; Rabbits; Rats; Rats, Inbred Strains; Stereoisomerism; Tegafur; Thymidine Phosphorylase | 1981 |
[Effects of UFT administered preoperatively in cases of gastric cancer (author's transl)].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Preoperative Care; Stomach Neoplasms; Tegafur; Uracil | 1981 |
Loss of tRNA 5-methyluridine methyltransferase and pseudouridine synthetase activities in 5-fluorouracil and 1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur)-treated Escherichia coli.
Topics: Escherichia coli; Fluorouracil; Intramolecular Transferases; Kinetics; Pseudouridine; Tegafur; tRNA Methyltransferases | 1982 |
[Gene mutation induction by the antitumor preparation ftorafur].
Topics: Animals; Azaguanine; Cell Line; Cells, Cultured; Chromosome Aberrations; Cricetinae; Dose-Response Relationship, Drug; Drug Resistance; Fluorouracil; Genes; Mutagenicity Tests; Mutagens; Mutation; Tegafur | 1982 |
Combination chemotherapy with cyclophosphamide and ftorafur against advanced L1210 murine leukemia.
Topics: Animals; Cyclophosphamide; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Leukemia L1210; Male; Mice; Tegafur | 1982 |
[Chemotherapy of advanced breast cancer--actual results ].
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Tegafur; Vincristine | 1982 |
Chemotherapeutic studies on N-nitrosoacetoxymethyl-methylamine-and 1,2-dimethylhydrazine-induced colonic tumors in rats: monotherapy with 5-fluorouracil, ftorafur, CGP 6809, and CGP 15'720A.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Dimethylnitrosamine; Fluorouracil; Male; Methylhydrazines; Neoplasms, Experimental; Nitrosourea Compounds; Phenylurea Compounds; Rats; Rats, Inbred Strains; Tegafur | 1982 |
Metabolic activation of ftorafur [R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil]: the microsomal oxidative pathway.
Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme System; Fluorouracil; In Vitro Techniques; Male; Microsomes, Liver; Oxidation-Reduction; Rabbits; Tegafur | 1982 |
Immunochemotherapy for advanced bladder cancer using FT-207, adriamycin and OK-432.
Topics: Adjuvants, Immunologic; Aged; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Injections, Intramuscular; Streptococcus; Suppositories; Tegafur; Ultrasonography; Urinary Bladder Neoplasms | 1982 |
Pharmacologic requirements for obtaining sensitization of human tumor cells in vitro to combined 5-Fluorouracil or ftorafur and X rays.
Topics: Cell Survival; Fluorouracil; HeLa Cells; Humans; Tegafur | 1982 |
[Anticancer effect of levamisole and tegafur on 1,2-dimethylhydrazine (DMH)-induced colonic cancers in rats].
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Colonic Neoplasms; Dimethylhydrazines; Fluorouracil; Levamisole; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Tegafur | 1982 |
Drug interaction of antitumor drugs. III. Antitumor activity of tegafur in lipopolysaccharide-treated mice.
Topics: Animals; Antineoplastic Agents; Drug Interactions; Fluorouracil; Kidney; Lipopolysaccharides; Liver; Male; Mice; Mixed Function Oxygenases; Proteins; Tegafur; Time Factors | 1982 |
[Significance of chemo-endocrine therapy in advanced breast cancer--a combined administration of tamoxifen, tegafur, and cyclophosphamide].
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Middle Aged; Tamoxifen; Tegafur | 1982 |
[Clinical trial of UFT in recurrent or advanced cancer].
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Combinations; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Rectal Neoplasms; Sigmoid Neoplasms; Tegafur; Uracil | 1982 |
[Transport of FT-207 to the blood, pancreatic juice, bile, and pancreatic tissue following rectal administration].
Topics: Antineoplastic Agents; Bile; Biological Transport; Fluorouracil; Humans; Pancreas; Pancreatic Juice; Suppositories; Tegafur; Tissue Distribution | 1982 |
[Two cases of carcinoid tumor of the stomach which responded to oral administration of UFT].
Topics: Administration, Oral; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms; Tegafur; Uracil | 1982 |
[Clinical study of preoperative chemotherapy of primary breast cancer. 1. Efficacy of a combined use of CPA (endoxan) and FT-207 (or 5-FU dry syrup)].
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Middle Aged; Preoperative Care; Tegafur | 1982 |
[Radiotherapy combined with tegafur for inoperable advanced gastric cancer].
Topics: Aged; Antineoplastic Agents; Female; Fluorouracil; Humans; Male; Middle Aged; Prognosis; Stomach Neoplasms; Tegafur | 1982 |
[Effect of FT-207 on bladder cancer in rats induced by BBN. II: The effect of oral administration of FT-207 during oncogenesis of bladder cancer].
Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Butylhydroxybutylnitrosamine; Fluorouracil; Male; Neoplasms, Experimental; Organ Size; Rats; Rats, Inbred Strains; Tegafur; Urinary Bladder; Urinary Bladder Neoplasms | 1982 |
[Evaluation of pre-operative chemotherapy using FT-207 suppositories combined with glutathione--with special reference to histopathological antitumor effect].
Topics: Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluorouracil; Glutathione; Humans; Male; Preoperative Care; Stomach Neoplasms; Suppositories; Tegafur | 1982 |
[Physiological effects and antitumor efficiency of ACNU in postoperative patients with stomach cancer--an evaluation of the treatment combined with FT-207 or 5-FU dry syrup].
Topics: Antineoplastic Agents; Bone Marrow; Carcinoembryonic Antigen; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Humans; Immunity, Cellular; Nimustine; Nitrosourea Compounds; Stomach Neoplasms; Tegafur | 1982 |
[Clinical effect of UFT on bladder cancer].
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Tegafur; Uracil; Urinary Bladder Neoplasms | 1982 |
[Concentration of 5-FU level in the tissue and blood of the patients with breast cancer by preoperative administration of UFT].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Lymphatic Metastasis; Preoperative Care; Tegafur; Uracil | 1982 |
[Clinical experiences with UFD-1].
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female; Fluorouracil; Humans; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasms; Stomach Neoplasms; Tegafur; Uracil | 1982 |
[A clinical investigation of the combination therapy of 1-(2-tetrahydrofuryl)-5-fluorouracil (FH) fine granules and 5-FU dry syrup].
Topics: Adult; Aged; Blood Platelets; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Tegafur | 1982 |
[Combined administration of futraful and esquinone for the treatment of advanced ovarian cancer].
Topics: Adenocarcinoma; Azirines; Carbazilquinone; Drug Therapy, Combination; Female; Fluorouracil; Humans; Ovarian Neoplasms; Tegafur | 1982 |
[Tissue concentration of 5-FU following pre-operative administration of FT-207].
Topics: Female; Fluorouracil; Humans; Intestinal Neoplasms; Intestine, Large; Lymph Nodes; Male; Middle Aged; Preoperative Care; Stomach Neoplasms; Tegafur; Tissue Distribution | 1982 |
[Clinical application of futraful suppositories in malignant head and neck cancer--effects of the therapy combined with radiation].
Topics: Aged; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Suppositories; Tegafur | 1982 |
[FT-207 maintenance therapy of malignant gynecologic cancer].
Topics: Antineoplastic Agents; Female; Fluorouracil; Humans; Middle Aged; Tegafur; Time Factors; Uterine Cervical Neoplasms; Uterine Neoplasms | 1982 |
[Clinical survey on cardiotoxicity of tegafur (FT-207)--compilation of a nationwide survey].
Topics: Administration, Oral; Adult; Aged; Electrocardiography; Female; Fluorouracil; Heart; Humans; Infusions, Parenteral; Male; Middle Aged; Neoplasms; Tegafur | 1982 |
[Clinical study of serum and tissue concentrations of FT-207 and 5-FU in patients with cancer of the large intestine following preoperative application of FT-207 suppositories].
Topics: Adult; Aged; Biological Assay; Female; Fluorouracil; Humans; Intestinal Neoplasms; Intestine, Large; Lymph Nodes; Male; Middle Aged; Rectal Neoplasms; Rectum; Suppositories; Tegafur; Tissue Distribution | 1982 |
[Clinical evaluation of Tegafur suppository in the treatment of uterine cancer--with special reference to the drug concentration in the blood, secretion from the pelvic dead space, and tissues of female genital organs].
Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Fluorouracil; Genitalia, Female; Humans; Middle Aged; Pelvis; Suppositories; Tegafur; Tissue Distribution; Uterine Cervical Neoplasms; Uterine Neoplasms | 1982 |
[Augmentation of chemotherapeutic efficaciousness of UFT by oral l-leucovorin--l-leucovorin factors enhancing cytotoxic activity of 5-fluorouracil].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Folic Acid; Humans; Leucovorin; Tegafur; Tumor Cells, Cultured; Uracil | 1995 |
[A case of gastric cancer responding well to MTX/5-FU (methotrexate/5-fluorouracil) and PMUE (CDDP, MMC, UFT, etoposide) therapies upon lymphnode recurrence].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Etoposide; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Stomach Neoplasms; Tegafur; Uracil | 1995 |
Pericardiac metastasis from advanced gastric cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Fluorouracil; Heart Neoplasms; Humans; Lentinan; Lymphatic Metastasis; Male; Middle Aged; Mitomycin; Pericardium; Pleural Neoplasms; Punctures; Stomach Neoplasms; Tegafur | 1995 |
[Blood levels of 5-FU and uracil on additional use of uracil in UFT therapy in gastrectomized patients].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Gastrectomy; Humans; Male; Stomach Neoplasms; Tegafur; Uracil | 1995 |
Fetal liver micronucleus assay in mice of 5-fluorouracil and related compounds.
Topics: Animals; Bone Marrow; Dose-Response Relationship, Drug; Female; Fetus; Fluorouracil; Liver; Male; Mice; Mice, Inbred C3H; Micronucleus Tests; Tegafur | 1993 |
Sensitivity of human KB cells expressing platelet-derived endothelial cell growth factor to pyrimidine antimetabolites.
Topics: Cell Division; Floxuridine; Fluorouracil; Humans; KB Cells; RNA; Tegafur; Thymidine Kinase; Thymidine Phosphorylase; Transfection | 1993 |
Postoperative prophylactic lipiodolization reduces the intrahepatic recurrence of hepatocellular carcinoma.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Chemotherapy, Cancer, Regional Perfusion; Disease-Free Survival; Epirubicin; Feasibility Studies; Female; Fluorouracil; Hepatectomy; Humans; Iodized Oil; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Postoperative Care; Prospective Studies; Survival Rate; Tegafur; Uracil | 1995 |
The antitumor effect of hyperthermia combined with fluorouracil and its analogues.
Topics: Animals; Combined Modality Therapy; Fluorouracil; Hyperthermia, Induced; Male; Mice; Mice, Inbred BALB C; Sarcoma, Experimental; Tegafur; Uracil | 1995 |
[Case report of long-term survivor of advanced gastric cancer associated with peritoneal dissemination successfully treated with cancer chemotherapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Gastrectomy; Humans; Leucovorin; Methotrexate; Peritoneal Neoplasms; Prognosis; Stomach Neoplasms; Tegafur; Uracil | 1995 |
[A case of multiple liver metastasis from remnant gastric cancer responding to leucovorin.5-FU+UFT therapy].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Liver Neoplasms; Male; Neoplasm, Residual; Stomach Neoplasms; Tegafur; Uracil | 1995 |
[Prevention of drug interactions and its countermeasure].
Topics: Animals; Arabinofuranosyluracil; Drug Interactions; Fluorouracil; Humans; Rats; Tegafur; Uracil | 1994 |
[A case of poorly differentiated hepatic cell carcinoma which showed 90% decrease in size after chemotherapy with intraarterial infusion of mitomycin C and oral administration of tegafur].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cell Division; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Mitomycin; Tegafur | 1994 |
[Tissue concentration of tegafur suppository in patients with head and neck cancer--concentration of 5-FU in cancer tissue].
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Nasal Mucosa; Paranasal Sinuses; Suppositories; Tegafur | 1994 |
In vivo 19F NMR comparative study of 5-fluorouracil, 1-(2-tetrahydrofuryl)-5-fluorouracil (FT) and an FT-uracil coadministration system in mouse tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Fluorine; Fluorouracil; Liver; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred ICR; Neoplasm Transplantation; Sarcoma 180; Tegafur; Uracil | 1994 |
Oral administration of BOF-A2 to rats with lung transplanted tumors results in increased 5-fluorouracil levels.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Disease Models, Animal; Drug Combinations; Drug Interactions; Fluorouracil; Lung; Lung Neoplasms; Male; Neoplasm Transplantation; Pyridines; Rats; Sarcoma, Yoshida; Tegafur; Transplantation, Heterologous; Uracil | 1994 |
[Innate resistance to thymidylate synthase inhibition after 5-fluorouracil treatment--a rationale of combined use of cisplatin and its optimal administration dose].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Synergism; Fluorouracil; Male; Rats; Sarcoma, Yoshida; Tegafur; Thymidylate Synthase; Uracil | 1994 |
[The concentration of FT in peripheral blood and portal blood after oral, intravenous or rectal administration].
Topics: Administration, Oral; Colonic Neoplasms; Fluorouracil; Humans; Infusions, Intravenous; Liver Neoplasms; Portal System; Suppositories; Tegafur | 1994 |
Effect of gastrectomy on the pharmacokinetics of tegafur, uracil, and 5-fluorouracil after oral administration of a 1:4 tegafur and uracil combination.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Gastrectomy; Humans; Stomach Neoplasms; Tegafur; Time Factors; Uracil | 1994 |
[The effect of induction chemotherapy with CBDCA, 5-FU and UFT in head and neck cancer].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Middle Aged; Tegafur; Uracil | 1994 |
[A comparative study on the serum and tissue 5-FU concentrations in patients with hepatocellular carcinoma after preoperative oral administration of UFT and 5'-DFUR].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Tegafur; Uracil | 1994 |
[Relationship between tissue concentrations of 5-FU and degeneration of tissues after UFT administration in patients with bladder tumor].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Middle Aged; Tegafur; Uracil; Urinary Bladder Neoplasms | 1993 |
[Efficacy of 48-hour infusion of 5-fluorouracil for gall bladder cancer].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Gallbladder Neoplasms; Humans; Infusions, Intravenous; Leucovorin; Male; Middle Aged; Mitomycin; Proteoglycans; Remission Induction; Survival Rate; Tegafur | 1993 |
The synthesis and in vitro and in vivo stability of 5-fluorouracil prodrugs which possess serum albumin binding potency.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Delivery Systems; Drug Stability; Fluorouracil; Half-Life; Hydrolysis; In Vitro Techniques; Prodrugs; Protein Binding; Rats; Serum Albumin; Tegafur | 1993 |
Suppression of mammary tumors by oral administration of 1-(2-tetrahydrofuryl)-5-fluorouracil in combination with uracil in SHN virgin mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Female; Fluorouracil; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Organ Size; Tegafur; Thymidine Kinase; Thymidylate Synthase; Uracil | 1993 |
The significance of preoperative chemotherapy for early gastric carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Preoperative Care; Prognosis; Stomach Neoplasms; Tegafur; Uracil | 1993 |
[Clinical efficacy of cis-diamminedichloroplatinum [II] and 5-fluorouracil (UFT) in advanced cancer of the alimentary tract].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Drug Administration Schedule; Esophageal Neoplasms; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Stomach Neoplasms; Tegafur; Uracil | 1993 |
[Tissue and serum levels of 5-FU in the patients with head and neck malignant tumors--influence of a streptococcal preparation OK-432].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Immunotherapy; Lymphatic Metastasis; Male; Middle Aged; Picibanil; Tegafur; Uracil | 1993 |
[A comparison of 5-fluorouracil concentration of 5-fluorouracil drip infusion versus orally UFT in plasma of same patients].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Tegafur; Uracil | 1993 |
Effect of 5-fluorouracil and UFT on experimental liver metastasis model of colorectal cancer using mouse colon 26 cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Combinations; Drug Screening Assays, Antitumor; Fluorouracil; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Tegafur; Uracil | 1993 |
[Pharmacodynamic study on the effectiveness of UFT against cancer of gastro-intestinal (GI) tract].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Fluorouracil; Gastrointestinal Neoplasms; Humans; Nucleolus Organizer Region; Tegafur; Uracil | 1993 |
[The present status of chemotherapy for hepatocellular carcinoma].
Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Doxorubicin; Drug Delivery Systems; Fluorouracil; Humans; Infusion Pumps; Infusions, Intra-Arterial; Liver Neoplasms; Mitomycin; Survival Rate; Tegafur; Uracil | 1993 |
A pharmacodynamic and pharmacokinetic study of fluoropyrimidines in a nude mouse system and in postoperative patients with gastric cancer.
Topics: Adenocarcinoma; Administration, Oral; Animals; Colonic Neoplasms; Fluorouracil; Gastrectomy; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Stomach Neoplasms; Tegafur; Uracil | 1993 |
Effects of 5-fluorouracil and a combination of tegafur and uracil (UFT) on nucleotide metabolism in L1210 ascites tumor.
Topics: Animals; Deoxyribonucleotides; Fluorouracil; Injections, Intraperitoneal; Leukemia L1210; Male; Mice; Tegafur; Uracil | 1993 |
[Studies on tissue concentration of tegafur, 5-fluorouracil, uracil after UFT administration together with the study of microangiography of colorectal cancer].
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Female; Fluorouracil; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Tegafur; Uracil | 1993 |
[A case of secondary leukemia induced by chemotherapy with a CDDP-based regimen for gastric cancer 5 years following radical resection].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Gastrectomy; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitomycin; Neoplasms, Second Primary; Proteoglycans; Stomach Neoplasms; Tegafur; Uracil | 1993 |
[Antitumor activity of BOF-A2, a new 5-fluorouracil derivative, against human cancers xenografted in nude mice by intermittent administration].
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Stomach Neoplasms; Tegafur; Uracil | 1993 |
Comparative studies on the metabolism of new fluorinated pyrimidine drugs in the liver by in vivo 19F magnetic resonance spectroscopic observation.
Topics: Alanine; Animals; Dihydrouracil Dehydrogenase (NAD+); Drug Interactions; Fluorouracil; Liver; Magnetic Resonance Spectroscopy; Male; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Pyridines; Rats; Rats, Wistar; Tegafur; Uracil | 1993 |
Dependence of the thymidylate synthase inhibition rate on the interval after the last administration of tegafur in sigmoid colon cancer patients.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Colon, Sigmoid; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Sigmoid Neoplasms; Tegafur; Thymidylate Synthase; Time Factors | 1993 |
[Evaluation of long-term administration of oral anti-cancer agent].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Stomach Neoplasms; Tegafur; Uracil | 1993 |
[A case of advance colon cancer responding to sequential methotrexate and 5-fluorouracil therapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Remission Induction; Tegafur; Uracil | 1993 |
White beeswax microspheres: a comparative in vitro evaluation of cumulative release of the anticancer agents fluorouracil and ftorafur.
Topics: Delayed-Action Preparations; Drug Stability; Fluorouracil; Microspheres; Particle Size; Tegafur; Waxes | 1993 |
5-Ethynyluracil (776C85): effects on the antitumor activity and pharmacokinetics of tegafur, a prodrug of 5-fluorouracil.
Topics: Animals; Carcinoma; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Drug Synergism; Enzyme Inhibitors; Fluorouracil; Male; Neoplasm Transplantation; Oxidoreductases; Prodrugs; Rats; Tegafur; Uracil | 1995 |
[A case of common bile duct cancer responding to MMC leucovorin, 5-FU, and UFT combination chemotherapy and radiation].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Common Bile Duct Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Mitomycin; Remission Induction; Tegafur; Uracil | 1996 |
Antitumor activity of 1 M tegafur-0.4 M 5-chloro-2,4-dihydroxypyridine-1 M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Colonic Neoplasms; Drug Combinations; Fluorouracil; Humans; Neoplasm Metastasis; Neoplasm Transplantation; Oxonic Acid; Prodrugs; Pyridines; Rats; Rats, Nude; RNA; Tegafur; Transplantation, Heterologous | 1996 |
[A case of advanced gastric cancer responding to chemotherapy and radiotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Ethanol; Fluorouracil; Gastrectomy; Humans; Injections, Intralesional; Liver Neoplasms; Male; Picibanil; Stomach Neoplasms; Tegafur; Uracil | 1996 |
Metabolites of 5-fluorouracil, alpha-fluoro-beta-alanine and fluoroacetic acid, directly injure myelinated fibers in tissue culture.
Topics: Animals; Animals, Newborn; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cerebellum; Culture Techniques; Fluorouracil; Immunohistochemistry; Mice; Mice, Inbred ICR; Microscopy, Phase-Contrast; Nerve Fibers, Myelinated; Tegafur | 1996 |
High-performance liquid chromatographic determination of 5-fluorouracil and its prodrugs, tegafur and 4-deoxy-5-fluorouracil, in rat plasma.
Topics: Animals; Antimetabolites, Antineoplastic; Biotransformation; Calibration; Chromatography, High Pressure Liquid; Fluorouracil; Prodrugs; Rats; Spectrophotometry, Ultraviolet; Tegafur | 1996 |
Biochemical modulation: its pharmacological basis and clinical applications. Proceedings of a meeting. Singapore, October 19, 1995.
Topics: Antimetabolites, Antineoplastic; Drug Combinations; Fluorouracil; Humans; Prodrugs; Tegafur; Uracil | 1997 |
Mechanism-based improvement in the therapeutic selectivity of 5-FU prodrug alone and under conditions of metabolic modulation.
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Drug Synergism; Fluorouracil; Leucovorin; Prodrugs; Rats; Tegafur; Uracil | 1997 |
[Immunotoxic effects of a new antineoplastic agent S-1 in mice--comparison with S-1, UFT and 5-FU].
Topics: Animals; Antibody Formation; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Body Weight; Dose-Response Relationship, Drug; Drug Combinations; Fluorouracil; Immune System; Immune Tolerance; Immunologic Tests; Mice; Mice, Inbred BALB C; Organ Size; Oxonic Acid; Pyridines; Spleen; Tegafur; Thymus Gland; Uracil | 1996 |
Determination of S-1 (combined drug of tegafur, 5-chloro-2,4-dihydroxypyridine and potassium oxonate) and 5-fluorouracil in human plasma and urine using high-performance liquid chromatography and gas chromatography-negative ion chemical ionization mass sp
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromatography, High Pressure Liquid; Drug Combinations; Drug Stability; Fluorouracil; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Oxonic Acid; Pyridines; Sensitivity and Specificity; Tegafur | 1997 |
[Case of acute immune hemolytic anemia developing during fluorouracil administration following surgery of colonic cancer].
Topics: Anemia, Hemolytic, Autoimmune; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Male; Middle Aged; Tegafur | 1997 |
Preventive effect of 1-(2-tetrahydrofuryl)-5-fluorouracil in combination with uracil on colonic carcinogenesis induced by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Cell Differentiation; Colorectal Neoplasms; Dimethylhydrazines; Fluorouracil; Male; Rats; Tegafur; Thymidine Kinase; Thymidylate Synthase; Uracil | 1997 |
Future directions in the adjuvant treatment of colon cancer.
Topics: Antidotes; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Combinations; Drug Therapy, Combination; Fluorouracil; Forecasting; Humans; Leucovorin; Tegafur; Uracil | 1997 |
A pharmacoeconomic comparison of UFT and 5-FU chemotherapy for colorectal cancer in South America.
Topics: Argentina; Brazil; Chemotherapy, Adjuvant; Colorectal Neoplasms; Costs and Cost Analysis; Drug Combinations; Drug Costs; Fluorouracil; Humans; Monte Carlo Method; South America; Tegafur; Uracil | 1997 |
[Concentrations of 5-fluorouracil (5-FU) in serum and tissues at venous injection of tegafur or 5-FU--clinical study on colorectal cancer].
Topics: Antimetabolites, Antineoplastic; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intravenous; Tegafur | 1998 |
Structure-activity relationship in Ftorafur (Tegafur) and related 5-FU prodrugs.
Topics: Animals; Antimetabolites, Antineoplastic; Fluorouracil; Humans; Indicators and Reagents; Leukemia L1210; Mice; Mice, Inbred Strains; Molecular Structure; Prodrugs; Serum Albumin; Structure-Activity Relationship; Tegafur | 1998 |
Colon cancer: new drug options improve on 5-FU.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Colonic Neoplasms; Deoxycytidine; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; Folic Acid Antagonists; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Survival Analysis; Tegafur; Thiophenes; Thymidylate Synthase; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome | 1998 |
Preclinical antitumor efficacy of S-1: a new oral formulation of 5-fluorouracil on human tumor xenografts.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Drug Combinations; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Oxonic Acid; Pyridines; Rats; Rats, Inbred F344; Rats, Nude; Species Specificity; Tegafur; Transplantation, Heterologous; Treatment Outcome; Tumor Cells, Cultured | 1998 |
Comparison of 5-fluorouracil pharmacokinetics in patients receiving continuous 5-fluorouracil infusion and oral uracil plus N1-(2'-tetrahydrofuryl)-5-fluorouracil.
Topics: Adenocarcinoma; Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Interactions; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Prodrugs; Tegafur; Uracil | 1998 |
[Complete remission of liver metastasis from rectal cancer following continuous oral administration of tegafur-uracil after intrahepatic arterial single injection of CDDP and 5-FU].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Fluorouracil; Hepatic Artery; Humans; Injections, Intra-Arterial; Liver Neoplasms; Male; Rectal Neoplasms; Remission Induction; Tegafur; Uracil | 1998 |
[Combined chemotherapy with low-dose cisplatin, tegafur and uracil in a case with neck recurrence of laryngeal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Humans; Laryngeal Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Tegafur; Uracil | 1998 |
5-Fluorouracil prodrug: role of anabolic and catabolic pathway modulation in therapy of colorectal cancer.
Topics: Animals; Body Weight; Colorectal Neoplasms; Female; Fluorouracil; Leucovorin; Metabolic Clearance Rate; Microsomes, Liver; Prodrugs; Rats; Rats, Inbred F344; Tegafur | 1995 |
Anticancer activity and toxicity of S-1, an oral combination of tegafur and two biochemical modulators, compared with continuous i.v. infusion of 5-fluorouracil.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Cell Division; Colorectal Neoplasms; Digestive System; Drug Combinations; Fluorouracil; Humans; Infusions, Intravenous; Neoplasm Transplantation; Oxonic Acid; Pyridines; Rats; Rats, Inbred F344; Sarcoma, Yoshida; Tegafur; Transplantation, Heterologous | 1998 |
Treatment of advanced gastric cancer with oral etoposide, leucovorin and tegafur: experience with an oral modification of the etoposide, leucovorin and 5-fluorouracil (ELF) regimen.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Fluorouracil; Humans; Leucovorin; Levoleucovorin; Male; Middle Aged; Stomach Neoplasms; Tegafur; Treatment Outcome | 1998 |
Persistent induction of apoptosis and suppression of mitosis as the basis for curative therapy with S-1, an oral 5-fluorouracil prodrug in a colorectal tumor model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Colorectal Neoplasms; Disease Models, Animal; Drug Combinations; Female; Fluorouracil; Mitosis; Neoplasm Transplantation; Oxonic Acid; Prodrugs; Pyridines; Rats; Rats, Inbred F344; Tegafur; Thymidylate Synthase; Treatment Outcome | 1999 |
[Preliminary evaluation of adjuvant chemotherapy against stage Ib or II gastric cancer].
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Fluorouracil; Gastrectomy; Humans; Immunohistochemistry; Male; Middle Aged; Mitomycin; Retrospective Studies; Stomach Neoplasms; Survival Rate; Tegafur; Thymidine Phosphorylase; Tumor Suppressor Protein p53; Uracil | 1999 |
[A case of advanced gallbladder cancer responding to neoadjuvant intra-arterial chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Duodenum; Epirubicin; Female; Fluorouracil; Gallbladder Neoplasms; Hepatectomy; Humans; Infusions, Intra-Arterial; Lymph Node Excision; Middle Aged; Neoadjuvant Therapy; Pancreatectomy; Tegafur; Uracil | 1999 |
[Effective chemo-endocrine combination therapy for obstructive-jaundice caused by multiple liver metastasis of recurrent breast cancer--a case report].
Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cholestasis; Cyclophosphamide; Doxorubicin; Drainage; Female; Floxuridine; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Mastectomy, Radical; Medroxyprogesterone Acetate; Tamoxifen; Tegafur; Toremifene; Uracil | 1999 |
Role of preoperative chemoradiation in the management of upper third thoracic esophageal squamous cell carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Esophageal Neoplasms; Esophagus; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Radiotherapy, High-Energy; Survival Rate; Tegafur | 1999 |
Patients' concerns about clinical trials in Japan.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Protocols; Clinical Trials as Topic; Control Groups; Cyclophosphamide; Disclosure; Epirubicin; Ethical Review; Female; Fluorouracil; Humans; Informed Consent; Research Design; Tegafur; Therapeutic Human Experimentation | 1999 |
UFT and its metabolites inhibit the angiogenesis induced by murine renal cell carcinoma, as determined by a dorsal air sac assay in mice.
Topics: 4-Butyrolactone; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cell Division; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Hydroxybutyrates; Kidney Neoplasms; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neovascularization, Pathologic; Tegafur; Tumor Cells, Cultured; Uracil | 1999 |
[Comparative study of histopathological effects of preoperative chemotherapy using UFT and in vitro MTT assay of colonoscopy specimens from patients with colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonoscopy; Colorectal Neoplasms; Drug Administration Schedule; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Tegafur; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Uracil | 1999 |
Complete response of a gastric primary after a short but toxic course of 'S-1' EORTC Early Clinical Studies Group.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Drug Combinations; Female; Fluorouracil; Humans; Oxonic Acid; Prodrugs; Pyridines; Remission Induction; Stomach Neoplasms; Tegafur | 1999 |
[Consideration of cancer home chemotherapy with cooperation between hospital and clinic].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cooperative Behavior; Drug Administration Schedule; Fluorouracil; Home Care Services, Hospital-Based; Humans; Neoplasms; Quality of Life; Tegafur; Uracil | 1999 |
[PMC (pharmacokinetic modulating chemotherapy) for advanced gastric cancer].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Gastrectomy; Humans; Infusions, Intravenous; Male; Middle Aged; Stomach Neoplasms; Survival Rate; Tegafur; Uracil | 1999 |
[Effective and low toxicity chemoradiotherapy for distant metastatic esophageal cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Esophageal Neoplasms; Fluorouracil; Humans; Infusions, Intravenous; Lung Neoplasms; Lymphatic Metastasis; Male; Tegafur; Uracil | 1999 |
[Long-term complete response in a case of unresectable rectal cancer following chemoradiation].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Floxuridine; Fluorouracil; Humans; Male; Middle Aged; Radiotherapy Dosage; Rectal Neoplasms; Remission Induction; Tegafur; Uracil | 2000 |
[A case of stage IVb (H2P0N4T4) gastric cancer successfully treated with neoadjuvant chemotherapy (PMFE therapy)].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Fluorouracil; Gastrectomy; Humans; Male; Mitomycin; Neoadjuvant Therapy; Remission Induction; Stomach Neoplasms; Tegafur; Uracil | 2000 |
[Improved QOL with cancer chemotherapy in two patients with breast cancer suffering form carcinomatous pleurisy and carcinomatous peritonitis].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Medroxyprogesterone Acetate; Middle Aged; Peritonitis; Pleurisy; Quality of Life; Tegafur; Uracil | 2000 |
[A case of AFP-producing gastric cancer after curative operation effectively treated with chemotherapies including hepatic arterial infusion therapy].
Topics: Adenocarcinoma; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Middle Aged; Stomach Neoplasms; Tegafur; Uracil | 2000 |
[Comparison of pharmacokinetics of 5-FU and alpha-fluoro-beta-alanine, a metabolite of 5-FU, in plasma after administration of UFT, tegafur, 5-FU or doxifluridine to rats].
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; beta-Alanine; Floxuridine; Fluorouracil; Male; Rats; Rats, Sprague-Dawley; Tegafur; Uracil | 2000 |
Reduction of 5-fluorouracil (5-FU) gastrointestinal (GI) toxicity resulting from the protection of thymidylate synthase (TS) in GI tissue by repeated simultaneous administration of potassium oxonate (Oxo) in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Colon; Diarrhea; Digestive System; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Fluorodeoxyuridylate; Fluorouracil; Ileum; Male; Oxonic Acid; Pyridines; Rats; Tegafur; Thymidylate Synthase | 2000 |
Therapeutic effect of 1 M tegafur-0.4 M 5-chloro-2, 4-dihydroxypridine-1 M potassium oxonate (S-1) on head and neck squamous carcinoma cells.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Combinations; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mice, SCID; Neoplasm Transplantation; Oxonic Acid; Pyridines; Survival Rate; Tegafur; Transplantation, Heterologous; Tumor Cells, Cultured; Uracil | 2000 |
Tissue distribution and biotransformation of potassium oxonate after oral administration of a novel antitumor agent (drug combination of tegafur, 5-chloro-2,4-dihydroxypyridine, and potassium oxonate) to rats.
Topics: Administration, Oral; Allopurinol; Animals; Antimetabolites, Antineoplastic; Area Under Curve; Biotransformation; Carbon Radioisotopes; Chlorpromazine; Drug Combinations; Drugs, Chinese Herbal; Fluorouracil; Glycyrrhiza; Intestine, Small; Male; Microsomes, Liver; Oxonic Acid; Paeonia; Pyridines; Rats; Rats, Inbred Strains; Sarcoma, Yoshida; Tegafur; Tissue Distribution; Triazines; Uracil; Xanthine Oxidase | 2000 |
[5-FU concentration in the serum and the tumor tissue after administration of UFT 200 mg/day to patients over 80 years of age with oral cancer].
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Mouth Neoplasms; Tegafur; Uracil | 2000 |
[A case of advanced rectal cancer with unresectable liver metastasis for which chemotherapy was markedly effective].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Liver Neoplasms; Middle Aged; Mitomycin; Rectal Neoplasms; Remission Induction; Tegafur; Uracil | 2000 |
[A case report of unresectable colon cancer that disappeared following pharmacokinetic modulation chemotherapy (PMC)].
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intravenous; Liver Neoplasms; Male; Peritoneal Neoplasms; Prognosis; Quality of Life; Remission Induction; Tegafur; Uracil | 2000 |
Postsurgical sequential methotrexate, fluorouracil, and leucovorin for stages 3 and 4 gastric carcinoma: A preliminary study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Fluorouracil; Gastrectomy; Humans; Leucovorin; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Stomach Neoplasms; Survival Rate; Tegafur; Uracil | 2000 |
Effect of consecutive lower-dose cisplatin in enhancement of 5-fluorouracil cytotoxicity in experimental tumor cells in vivo.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Synergism; Enzyme Induction; Fluorouracil; Folic Acid; Male; Methionine; Mice; Neoplasm Transplantation; Oxonic Acid; Pyridines; Rats; Sarcoma, Yoshida; Tegafur | 2000 |
[A successful case of preoperative intermittent hepatic arterial infusion of high-dose 5-FU and pharmacokinetic modulating chemotherapy against unresectable liver metastasis of colon cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Hepatectomy; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Sigmoid Neoplasms; Tegafur; Uracil | 2000 |
An experimental model of tumor dormancy therapy for advanced head and neck carcinoma.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Biotransformation; Cell Division; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug Combinations; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Isoenzymes; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Organic Chemicals; Oxonic Acid; Probucol; Prodrugs; Prostaglandin-Endoperoxide Synthases; Pyridines; Tegafur; Telomerase; Xenograft Model Antitumor Assays | 2000 |
Roles of cytochromes P450 1A2, 2A6, and 2C8 in 5-fluorouracil formation from tegafur, an anticancer prodrug, in human liver microsomes.
Topics: Antimetabolites, Antineoplastic; Aryl Hydrocarbon Hydroxylases; Baculoviridae; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2C8; Cytochrome P-450 Enzyme System; Fluorouracil; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Prodrugs; Recombinant Proteins; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Tegafur | 2000 |
A novel weekday-on/weekend-off UFT schedule.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Fluorouracil; Humans; Male; Rats; Sarcoma; Survival Analysis; Tegafur; Uracil | 2000 |
Bioactivation of tegafur to 5-fluorouracil is catalyzed by cytochrome P-450 2A6 in human liver microsomes in vitro.
Topics: Antimetabolites, Antineoplastic; Aryl Hydrocarbon Hydroxylases; Biotransformation; Catalysis; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Fluorouracil; Humans; In Vitro Techniques; Microsomes, Liver; Mixed Function Oxygenases; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Tegafur | 2000 |
[Oral chemotherapeutic agents: the roles in cancer chemotherapy].
Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Fluorouracil; Humans; Neoplasms; Oxonic Acid; Pyridines; Tegafur; Uracil | 1999 |
[A case of pulmonary metastases of breast cancer responding remarkably to combined chemotherapy with 5-fluorouracil and low-dose cisplatin].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Humans; Lung Neoplasms; Mastectomy; Middle Aged; Tegafur; Uracil | 2000 |
[Outcomes of home anti-cancer chemotherapy--estimation of hepatic arterial infusion chemotherapy for patients with multiple liver metastases].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Fluorouracil; Hepatic Artery; Home Care Services; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitomycin; Quality of Life; Stomach Neoplasms; Survival Rate; Tegafur; Treatment Outcome; Uracil | 2000 |
[Long survival in a case of unresectable hepatic metastasis from rectal carcinoma treated with second-look hepatectomy plus pharmacokinetic modulating chemotherapy (PMC)].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Infusion Pumps; Infusions, Intra-Arterial; Liver Neoplasms; Mitomycin; Rectal Neoplasms; Reoperation; Tegafur; Uracil | 2001 |
Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: a novel target mechanism concept for pharmacokinetic modulating chemotherapy.
Topics: Adenocarcinoma; Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Division; Colorectal Neoplasms; DNA, Neoplasm; Dose-Response Relationship, Drug; Flow Cytometry; Fluorouracil; Humans; Infusions, Intravenous; Tegafur; Tumor Cells, Cultured; Uracil | 2001 |
[A case of gastric cancer with liver metastases successfully treated with combination therapy of systemic and hepatic arterial infusion chemotherapy].
Topics: Administration, Oral; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Drug Combinations; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Liver Neoplasms; Male; Mitomycin; Stomach Neoplasms; Tegafur; Uracil | 2001 |
[A case of advanced gastric cancer complicated with liver metastases responding remarkably to combined chemotherapy with 5-fluorouracil and low-dose cisplatin, with UFT and low-dose cisplatin for maintenance on an outpatient basis].
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Fluorouracil; Humans; Liver Neoplasms; Male; Stomach Neoplasms; Tegafur; Uracil | 2001 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, Adjuvant; Clinical Trials as Topic; Colonic Neoplasms; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Levamisole; Neoplasm Staging; Semustine; Tegafur; Vincristine | 2001 |
Involvement of microsomal cytochrome P450 and cytosolic thymidine phosphorylase in 5-fluorouracil formation from tegafur in human liver.
Topics: Antimetabolites, Antineoplastic; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Cytosol; Dose-Response Relationship, Drug; Fluorouracil; Humans; Kinetics; Liver; Microsomes, Liver; Pyridines; Tegafur; Thymidine Phosphorylase; Time Factors | 2001 |
Rat cytochrome p450 1A and 3A enzymes involved in bioactivation of tegafur to 5-fluorouracil and autoinduced by tegafur in liver microsomes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Fluorouracil; Male; Microsomes, Liver; Mixed Function Oxygenases; Prodrugs; Rats; Rats, Wistar; Tegafur | 2001 |
Intestinal permeability in patients with chemotherapy-induced stomatitis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Digestive System Neoplasms; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Gemcitabine; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Intestinal Absorption; Intestinal Mucosa; Lactulose; Leucovorin; Male; Mannitol; Middle Aged; Paclitaxel; Permeability; Stomatitis; Tegafur; Treatment Outcome; Xylose | 2001 |
Effects of 5-fluorouracil on the drug-metabolizing enzymes of the small intestine and the consequent drug interaction with nifedipine in rats.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Biotransformation; Calcium Channel Blockers; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Fluorouracil; Glucuronosyltransferase; Glutathione Transferase; Immunoblotting; Intestinal Mucosa; Intestine, Small; Male; Microsomes; NADPH-Ferrihemoprotein Reductase; Nifedipine; Oxonic Acid; Pentosyltransferases; Pyridines; Rats; Rats, Inbred Strains; Tegafur | 2001 |
Expression of CYP2A6 in tumor cells augments cellular sensitivity to tegafur.
Topics: Antimetabolites, Antineoplastic; Aryl Hydrocarbon Hydroxylases; Cell Division; Colonic Neoplasms; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Fluorouracil; Gene Expression; Humans; Hydroxylation; Microsomes; Mixed Function Oxygenases; Tegafur; Transfection; Tumor Cells, Cultured | 2001 |
[Relationship between the anti-metastatic effect of UFT and in vitro chemosensitivity to 5-FU in metastatic tumors from orthotopic implanted colon cancer in nude rats].
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Combinations; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Neoplasm Transplantation; Rats; Rats, Nude; Tegafur; Transplantation, Heterologous; Uracil | 2001 |
Correct fluorouracil (5-FU) half-life comparator for a 5-FU prodrug plus a dihydropyrimidine dehydrogenase inhibitor.
Topics: Antimetabolites, Antineoplastic; Drug Combinations; Fluorouracil; Half-Life; Humans; Oxonic Acid; Pyridines; Reference Values; Statistics as Topic; Tegafur | 2001 |
A pharmacological study of the weekday-on/weekend-off oral UFT schedule in colorectal cancer patients.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Tegafur; Uracil | 2001 |
[Experimental study of radiosensitizing effect of analogs of purines and pyrimidine bases in cultured HeLa cells].
Topics: Allopurinol; Antimetabolites; Antimetabolites, Antineoplastic; Cell Survival; Cobalt Radioisotopes; Fluorouracil; Gamma Rays; HeLa Cells; Humans; Lethal Dose 50; Mercaptopurine; Phosphodiesterase Inhibitors; Radiation-Sensitizing Agents; Radiotherapy; Radiotherapy Dosage; Tegafur; Theophylline | 2001 |
Complete response achieved following administration of S-1 in a patient with adrenal gland metastasis of 5-FU-resistant gastric cancer: a case report.
Topics: Adrenal Gland Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Drug Resistance, Neoplasm; Fluorouracil; Humans; Male; Middle Aged; Oxonic Acid; Pyridines; Remission Induction; Stomach Neoplasms; Tegafur | 2001 |
[Efficacy of intraperitoneal chemotherapy for peritoneal recurrence of gastric carcinoma].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Infusion Pumps, Implantable; Infusions, Parenteral; Mitomycin; Peritoneal Neoplasms; Stomach Neoplasms; Tegafur; Uracil | 2001 |
Fluorouracil (5FU) pharmacokinetics in 5FU prodrug formulations with a dihydropyrimidine dehydrogenase inhibitor.
Topics: Antimetabolites, Antineoplastic; Chemistry, Pharmaceutical; Dihydrouracil Dehydrogenase (NAD+); Drug Combinations; Fluorouracil; Half-Life; Humans; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Oxonic Acid; Prodrugs; Pyridines; Tegafur | 2001 |
Plasma, intestine and tumor levels of 5-fluorouracil in mice bearing L1210 ascites tumor following oral administration of 5-fluorouracil, UFT (mixed compound of tegafur and uracil), carmofur and 5'-deoxy-5-fluorouridine.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Drug Combinations; Floxuridine; Fluorouracil; Intestinal Mucosa; Leukemia L1210; Male; Mice; Tegafur; Uracil | 2001 |
Pathologic downstaging of T3-4Nx rectal cancer after chemoradiation: 5-fluorouracil vs. Tegafur.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Rectal Neoplasms; Tegafur | 2001 |
Stereoselective metabolism and pharmacokinetics of tegafur.
Topics: Antimetabolites, Antineoplastic; Fluorouracil; Humans; Neoplasms; Stereoisomerism; Tegafur | 2001 |
Oral fluoropyrimidines: are they the equivalent of parenteral infusional 5-fluorouracil?
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Infusions, Intravenous; Tegafur; Uracil | 2001 |
[A case of spindle cell type hepatocellular carcinoma responding to hepatic intra-arterial infusion chemotherapy].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Middle Aged; Tegafur; Uracil | 2002 |
[Dormant chemotherapy by low-dose FP and low-dose UFT-E in recurrent gastric cancer with long-term survival--a case report].
Topics: Adenocarcinoma, Papillary; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Lymph Node Excision; Lymphatic Metastasis; Male; Middle Aged; Stomach Neoplasms; Survivors; Tegafur; Uracil | 2002 |
[Three cases of advanced gastric cancer treated by TS-1 in combination with low-dose cisplatinum].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Oxonic Acid; Pyridines; Stomach Neoplasms; Tegafur | 2002 |
Recent development of anti-cancer drugs for treatment of GI malignancies in Japan.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Capecitabine; Deoxycytidine; Drug Combinations; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Pyridines; Tegafur | 2002 |
gamma-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor.
Topics: Angiogenesis Inhibitors; Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Carcinoma; Carcinoma, Renal Cell; Chemotaxis; Colonic Neoplasms; DNA Replication; Drug Combinations; Endothelial Growth Factors; Endothelium, Vascular; Female; Fibroblast Growth Factor 2; Floxuridine; Fluorouracil; Humans; Intercellular Signaling Peptides and Proteins; Kidney Neoplasms; Lung Neoplasms; Lymphokines; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Neoplasm Proteins; Neovascularization, Pathologic; Prodrugs; Prostheses and Implants; Recombinant Proteins; Sodium Oxybate; Stomach Neoplasms; Tegafur; Tumor Cells, Cultured; Uracil; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Xenograft Model Antitumor Assays | 2001 |
[A case of gastric cancer with paraaortic lymph node metastasis responding to preoperative chemotherapy and surviving 4 years and 4 months after total gastrectomy].
Topics: Adenocarcinoma, Scirrhous; Aged; Antineoplastic Combined Chemotherapy Protocols; Aorta; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Gastrectomy; Humans; Leucovorin; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Stomach Neoplasms; Survivors; Tegafur; Uracil | 2002 |
[A case of complete response (CR) persisting for 2 years and 10 months from UFT-E in a patient with liver metastasis of gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Fluorouracil; Gastrectomy; Humans; Leucovorin; Liver Neoplasms; Lymph Node Excision; Male; Methotrexate; Middle Aged; Remission Induction; Stomach Neoplasms; Tegafur; Uracil | 2002 |
[A case of liver metastasis of rectal cancer demonstrating complete response to 5-FU + Leucovorin + UFT].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Male; Middle Aged; Rectal Neoplasms; Remission Induction; Tegafur; Uracil | 2002 |
[Patient preference for oral chemotherapy].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Fluorouracil; Humans; Infusions, Intravenous; Patient Acceptance of Health Care; Tegafur | 2002 |
[Capsule instead of infusion--new oral chemotherapy option].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Palliative Care; Tegafur; Uracil | 2002 |
[A case in which TS-1, an orally-administered 5-FU chemotherapeutic agent, showed marked effectiveness against scirrhous type gastric cancer with multiple organ metastases].
Topics: Adenocarcinoma, Scirrhous; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female; Fluorouracil; Humans; Neoplasm Metastasis; Oxonic Acid; Pyridines; Quality of Life; Stomach Neoplasms; Tegafur | 2002 |
[Three cases of recurrent gastric cancer responding to TS-1 therapy following combination therapy with 5-fluorouracil, mitomycin C and cisplatin].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Mitomycin; Oxonic Acid; Peritoneal Neoplasms; Pyridines; Stomach Neoplasms; Tegafur | 2002 |
[A case of unresectable gastric cancer complicated by a serious hepatic disorder and Virchow lymph node metastasis in which FP therapy and TS-1 administration were effective].
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Female; Fluorouracil; Humans; Liver Diseases; Lymphatic Metastasis; Oxonic Acid; Pyridines; Stomach Neoplasms; Tegafur | 2002 |
[Concentration of FT and CDHP and 5-FU in the ascites fluid of patient with peritoneal carcinomatosis after new anti-cancer drug TS-1 oral administration].
Topics: Adenocarcinoma; Administration, Oral; Antimetabolites, Antineoplastic; Ascitic Fluid; Drug Combinations; Fluorouracil; Humans; Male; Middle Aged; Oxonic Acid; Peritoneal Neoplasms; Pyridines; Stomach Neoplasms; Tegafur | 2002 |
[Gastric cancer with multiple liver metastases, which responded significantly to oral administration of TS-1 following intravenous FMP therapy under hospitalization].
Topics: Adenocarcinoma; Administration, Oral; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Drug Combinations; Fluorouracil; Hospitalization; Humans; Infusions, Intravenous; Liver Neoplasms; Male; Mitomycin; Oxonic Acid; Pyridines; Stomach Neoplasms; Tegafur; Treatment Outcome | 2002 |
[A case of unresectable rectal cancer with liver and pulmonary metastases that responded remarkably to pharmacokinetic modulating chemotherapy].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; Humans; Infusion Pumps, Implantable; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Quality of Life; Rectal Neoplasms; Tegafur; Uracil | 2002 |
[A trial of continuous and biweekly low-dose cisplatin and 5-FU with UFT chemotherapy for esophageal cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Esophageal Neoplasms; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Survival Rate; Tegafur; Uracil | 2002 |
[A case of colon metastasis to the lung treated successfully with combined chemotherapy of CPT-11 and 5'-DFUR].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Drug Combinations; Floxuridine; Fluorouracil; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Rectal Neoplasms; Tegafur; Uracil | 2002 |
Determination of the 5-fluorouracil and N1(2'-furanidyl)uracil in the presence of tegafur by zero-crossing first derivative spectrometry.
Topics: Fluorouracil; Spectrophotometry, Ultraviolet; Tegafur | 2002 |
Oral uracil/ftorafur (UFT) plus leucovorin as first-line chemotherapy and salvage therapy with weekly high-dose 5-fluorouracil/leucovorin for the treatment of metastatic colorectal cancer.
Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms; Salvage Therapy; Tegafur; Uracil | 2002 |
Cytosolic and microsomal activation of doxifluridine and tegafur to produce 5-fluorouracil in human liver.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Cytosol; Floxuridine; Fluorouracil; Humans; In Vitro Techniques; Microsomes, Liver; Mixed Function Oxygenases; Steroid Hydroxylases; Tegafur; Thymidine Phosphorylase | 2002 |
[A case of multiple liver metastases from colon cancer successfully treated with modified pharmacokinetic modulating chemotherapy using Leucovorin].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Male; Middle Aged; Remission Induction; Tegafur; Uracil | 2002 |
[Two patients with recurrent colon cancer who underwent surgery following a combination of irinotecan and UFT].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Humans; Irinotecan; Leucovorin; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Tegafur; Uracil | 2002 |
[A case of postoperative hepatic metastasis from gastric cancer responding to hepatic arterial infusion chemotherapy of paclitaxel].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Drug Administration Schedule; Drug Combinations; Fluorouracil; Gastrectomy; Humans; Liver Neoplasms; Male; Paclitaxel; Stomach Neoplasms; Tegafur; Uracil | 2002 |
[5-FU pharmacokinetic study of 5-FU hepato-arterial infusion with oral UFT].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Tegafur; Uracil | 2002 |
[Modified pharmacokinetic modulation chemotherapy (PMC) with medication of UFT and intraarterial infusion of 5-FU for advanced unresectable HCC].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Drug Combinations; Female; Fluorouracil; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Survival Rate; Tegafur; Uracil | 2002 |
[Effectiveness of chemotherapy for outpatients with gastric or colorectal cancer].
Topics: Adult; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Outpatients; Oxonic Acid; Paclitaxel; Pyridines; Retrospective Studies; Stomach Neoplasms; Tegafur | 2002 |
[A case of advanced gastric adenocarcinoma with mild elevation of serum SCC that responded remarkably to adjuvant chemotherapy of ADM, CDDP, ETP and 5-FU (ACVF)].
Topics: Adenocarcinoma; Aged; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Drug Administration Schedule; Drug Combinations; Etoposide; Fluorouracil; Gastrectomy; Humans; Lymphatic Metastasis; Male; Oxonic Acid; Pyridines; Remission Induction; Serpins; Stomach Neoplasms; Tegafur | 2003 |
Prevention of peritoneal metastasis of human gastric cancer cells in nude mice by S-1, a novel oral derivative of 5-Fluorouracil.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Disease Models, Animal; Drug Combinations; Female; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Fluorescence; Oxonic Acid; Peritoneal Neoplasms; Pyridines; Stomach Neoplasms; Tegafur; Tumor Cells, Cultured | 2003 |
[A case report--TS-1/CDDP combined chemotherapy found effective for metastatic recurrence after operation for colon cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colon, Sigmoid; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Fluorouracil; Gastrectomy; Humans; Infusions, Intravenous; Leucovorin; Lymphatic Metastasis; Male; Oxonic Acid; Pyridines; Sigmoid Neoplasms; Splenic Neoplasms; Stomach Neoplasms; Tegafur | 2003 |
[A case of advanced pancreatic cancer with multiple liver metastasis that improved remarkably with use of low-dose cisplatin and TS-1].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Infusions, Intravenous; Liver Neoplasms; Male; Middle Aged; Oxonic Acid; Pancreatic Neoplasms; Pyridines; Quality of Life; Tegafur | 2003 |
Role of platelet-derived endothelial cell growth factor/thymidine phosphorylase in fluoropyrimidine sensitivity.
Topics: Antimetabolites; Antimetabolites, Antineoplastic; Colonic Neoplasms; Fluorouracil; Gene Expression Regulation; Humans; Lung Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Tegafur; Thymidine Phosphorylase; Trifluridine; Tumor Cells, Cultured | 2003 |
Determination of 5-fluorouracil and its prodrug tegafur in plasma and tissue by high-performance liquid chromatography in a single injection: validation for application in clinical pharmacokinetic studies.
Topics: Antimetabolites, Antineoplastic; Chromatography, High Pressure Liquid; Fluorouracil; Humans; Prodrugs; Tegafur; Tissue Distribution | 2003 |
Preparation and characterization of chitosan microspheres containing doxifluridine.
Topics: Animals; Antimetabolites, Antineoplastic; Chemistry, Pharmaceutical; Chitin; Chitosan; Drug Implants; Floxuridine; Fluorouracil; Male; Mice; Microspheres; Rats; Rats, Wistar; Tegafur | 2003 |
Experimental study to evaluate the usefulness of S-1 in a model of peritoneal dissemination of gastric cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Disease Models, Animal; Drug Combinations; Eating; Female; Fluorouracil; Japan; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Oxonic Acid; Peritoneal Neoplasms; Pyridines; Stomach Neoplasms; Survival Analysis; Tegafur; Time Factors | 2003 |
S-1 in the treatment of advanced and recurrent gastric cancer: current state and future prospects.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Forecasting; Humans; Japan; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Pyridines; Severity of Illness Index; Stomach Neoplasms; Survival Analysis; Tegafur; Time Factors; Treatment Outcome | 2003 |
Dihydropyrimidine dehydrogenase (DPD) activity in gastric cancer tissue and effect of DPD inhibitory fluoropyrimidines.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Dihydrouracil Dehydrogenase (NADP); Disease Progression; Drug Combinations; Enzyme Inhibitors; Fluorouracil; Humans; Japan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Oxidoreductases; Oxonic Acid; Peritoneal Neoplasms; Prognosis; Pyridines; Statistics as Topic; Stomach Neoplasms; Survival Analysis; Tegafur; Treatment Outcome; Uracil | 2003 |
NICE recommends new treatment for breast and bowel cancer.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Colonic Neoplasms; Deoxycytidine; Docetaxel; Female; Fluorouracil; Humans; Paclitaxel; Practice Guidelines as Topic; Taxoids; Tegafur; Uracil | 2003 |
[A case of advanced gastric cancer with lymphangitis carcinomatosa of the lung, successfully treated with paclitaxel and TS-1].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Drug Resistance, Neoplasm; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Lymphangitis; Male; Oxonic Acid; Paclitaxel; Pyridines; Stomach Neoplasms; Tegafur | 2003 |
Effect of combination of TS-1 and low-dose cisplatin on sarcoma-180 mouse sarcoma.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Cisplatin; Dose-Response Relationship, Drug; Drug Combinations; Fluorouracil; Male; Mice; Oxonic Acid; Pyridines; Sarcoma 180; Tegafur; Tissue Distribution | 2003 |
Effects of oral UFT combined with or without zoledronic acid on bone metastasis in the 4T1/luc mouse breast cancer.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Diphosphonates; Disease Models, Animal; Drug Combinations; Female; Fluorouracil; Imidazoles; Luciferases; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Osteoclasts; Tegafur; Uracil; Zoledronic Acid | 2003 |
[A case of multiple lung metastases from colon cancer after sigmoidectomy treated effectively by chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colon, Sigmoid; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Postoperative Complications; Sigmoid Neoplasms; Tegafur; Uracil | 2003 |
[A case of advanced gastric cancer with liver and intra-abdominal lymph node metastasis treated by hypertensive selective chemotherapy with pharmacokinetic modulating chemotherapy].
Topics: Adenocarcinoma; Aged; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Pancreatic Neoplasms; Stomach Neoplasms; Tegafur | 2003 |
Plasma concentrations of 5-fluorouracil and F-beta-alanine following oral administration of S-1, a dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine, as compared with protracted venous infusion of 5-fluorouracil.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; beta-Alanine; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Enzyme Inhibitors; Fluorouracil; Gastrointestinal Neoplasms; Humans; Infusions, Intravenous; Male; Middle Aged; Oxidoreductases; Oxonic Acid; Pyridines; Tegafur; Uracil | 2003 |
A cost comparison of oral tegafur plus uracil/folinic acid and parenteral fluorouracil for colorectal cancer in Canada.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Canada; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Drug Combinations; Drug Therapy, Combination; Female; Fluorouracil; Health Care Costs; Humans; Infusions, Parenteral; Leucovorin; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Retrospective Studies; Tegafur; Uracil | 2003 |
[A case of multiple liver metastases from colon cancer successfully treated with pharmacokinetic modulating chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Infusions, Intravenous; Liver Neoplasms; Middle Aged; Tegafur; Uracil | 2003 |
Sensitive liquid chromatographic assay for the simultaneous determination of 5-fluorouracil and its prodrug, tegafur, in beagle dog plasma.
Topics: Animals; Antimetabolites, Antineoplastic; Calibration; Chromatography, High Pressure Liquid; Dogs; Fluorouracil; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tegafur | 2003 |
Superior antitumour activity of S-1 in tumours with a high dihydropyrimidine dehydrogenase activity.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Dihydrouracil Dehydrogenase (NADP); Dose-Response Relationship, Drug; Drug Combinations; Fluorouracil; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Oxonic Acid; Pyridines; RNA, Neoplasm; Stomach Neoplasms; Tegafur; Thymidylate Synthase; Xenograft Model Antitumor Assays | 2003 |
[Results of prophylactic hepatic arterial chemotherapy for liver metastases of Dukes C colorectal cancer--correlation with tumoral expression of dihydropyrimidine dehydrogenase, thymidylate synthase, p53, or orotate phosphoribosyl transferase].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Orotate Phosphoribosyltransferase; Proportional Hazards Models; RNA, Messenger; Tegafur; Thymidylate Synthase; Tumor Suppressor Protein p53; Uracil | 2003 |
[A case of liver and lung metastases of rectal cancer responding well to 5-FU hepato-arterial infusion (HAI) with combined use of oral UFT].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Combinations; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Lung Neoplasms; Male; Rectal Neoplasms; Tegafur; Uracil | 2003 |
[A case of hepatic metastasis and local recurrence from rectal cancer responding to hepatic arterial infusion and systemic chemotherapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Drug Combinations; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Neoplasm Recurrence, Local; Rectal Neoplasms; Tegafur; Uracil | 2003 |
[Pancytopenia and ARDS with high dose hepatic arterial infusion].
Topics: Aged; Antimetabolites, Antineoplastic; Cisplatin; Drug Combinations; Female; Fluorouracil; Gastrectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Oxonic Acid; Pancytopenia; Pyridines; Respiratory Distress Syndrome; Stomach Neoplasms; Tegafur | 2003 |
[Long-term survival after neck lymph node metastases from sigmoid colon cancer--a case report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colon, Sigmoid; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Lymph Nodes; Lymphatic Metastasis; Neck; Sigmoid Neoplasms; Survivors; Tegafur; Uracil | 2003 |
Modified pharmacokinetic modulating chemotherapy using 5-fluorouracil, UFT, and taxotere (docetaxel) for advanced gastric cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Docetaxel; Fluorouracil; Humans; Infusions, Intravenous; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Stomach Neoplasms; Taxoids; Tegafur; Treatment Outcome; Uracil | 2003 |
A case of prurigo-type drug eruptions due to UFT.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Breast Neoplasms; Drug Eruptions; Female; Fluorouracil; Follow-Up Studies; Humans; Immunohistochemistry; Middle Aged; Prurigo; Risk Assessment; Tegafur | 2003 |
[Support of TS-1, 5-FU preparation containing potent DPD inhibitor by determination of urinary uracil/serum 5-FU clearance].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Oxonic Acid; Pyridines; Stomach Neoplasms; Tegafur; Uracil | 2003 |
[A case of advanced gastric cancer with multiple liver metastases responding completely to hepatic arterial infusion and systemic chemotherapies].
Topics: Adenocarcinoma; Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Fluorouracil; Gastrectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Remission Induction; Stomach Neoplasms; Tegafur; Uracil | 2003 |
18F-FDG positron emission tomography staging and restaging in rectal cancer treated with preoperative chemoradiation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorodeoxyglucose F18; Fluorouracil; Humans; Liver Neoplasms; Male; Neoplasm Staging; Prospective Studies; Radiopharmaceuticals; Radiotherapy Dosage; Rectal Neoplasms; Tegafur; Tomography, Emission-Computed | 2004 |
[A case of gastric cancer with a synchronous hepatic metastasis responding to postoperative oral administration of UFT and intermittent intrahepatic arterial chemotherapy of 5-FU].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Combinations; Fluorouracil; Gastrectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Lymph Node Excision; Male; Neoplasms, Multiple Primary; Remission Induction; Stomach Neoplasms; Tegafur; Uracil | 2004 |
[A case of highly advanced ascending colon cancer with multiple bone and liver metastases and pleuritis carcinomatosa treated with pharmacokinetic modulating chemotherapy and low-dose CPT-11].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Pleurisy; Quality of Life; Tegafur; Uracil | 2004 |
Adjuvant chemotherapy for adenocarcinoma of the lung--is the standard of care ready for change?
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Fluorouracil; Humans; Lung Neoplasms; Prodrugs; Tegafur; Uracil | 2004 |
Alternate-day oral therapy with TS-1 for advanced gastric cancer.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Middle Aged; Oxonic Acid; Pyridines; Stomach Neoplasms; Tegafur; Treatment Outcome | 2004 |
[Tumoral dihydropyrimidine dehydrogenase expression and efficacy of 5-fluorouracil plus leucovorin plus UFT therapy in patients with colorectal cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Tegafur; Uracil | 2004 |
S-1-induced, prolonged complete regression of lung metastasis from gastric cancer refractory to 5'-DFUR: a case report with pharmacokinetic study.
Topics: Adenocarcinoma, Mucinous; Administration, Oral; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Drug Administration Schedule; Drug Combinations; Esophagectomy; Female; Floxuridine; Fluorouracil; Gastrectomy; Humans; Lung Neoplasms; Middle Aged; Oxonic Acid; Pyridines; Radiography, Thoracic; Remission Induction; Stomach Neoplasms; Tegafur; Tomography, X-Ray Computed | 2004 |
Safety and efficacy of S-1, a novel oral fluorouracil antitumor drug, for a chronic renal failure patient maintained on hemodialysis.
Topics: Administration, Oral; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Kidney Failure, Chronic; Liver Neoplasms; Male; Oxonic Acid; Pyridines; Renal Dialysis; Stomach Neoplasms; Tegafur; Tomography, X-Ray Computed | 2004 |
Dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine S-1 may be effective against peritoneal dissemination in gastric cancer.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Ascites; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Female; Fluorouracil; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Mice, Nude; Oxonic Acid; Peritoneal Neoplasms; Pyridines; Stomach Neoplasms; Survival Rate; Tegafur; Tumor Cells, Cultured | 2004 |
Schedule-dependent synergism of vinorelbine and 5-fluorouracil/UFT against non-small cell lung cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Fluorouracil; Humans; Immunohistochemistry; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Survival Analysis; Tegafur; Thymidylate Synthase; Transplantation, Heterologous; Tumor Cells, Cultured | 2004 |
[A case of successful management of nonresectable pancreas cancer with liver metastasis by intra-arterial infusion chemotherapy with gemcitabine hydrochloride, 5-FU, CDDP and administration of tegafur/uracil].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Drug Administration Schedule; Drug Combinations; Fluorouracil; Gemcitabine; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Male; Pancreatic Neoplasms; Quality of Life; Tegafur; Uracil | 2004 |
[Gastric cancer with liver metastasis effectively treated by intra-hepatic arterial infusion].
Topics: Administration, Oral; Adult; Aged; Agmatine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Mitomycin; Oxonic Acid; Proteoglycans; Pyridines; Stomach Neoplasms; Succinates; Tegafur; Treatment Outcome | 2004 |
[A case report of the 8 year survivor--unresectable liver metastases from advanced gastric cancer (Stage IV) were completely responsive, after 4 years from a total sequential gastrectomy, combining docetaxel treatment to regress the recurrence].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Drug Combinations; Fluorouracil; Gastrectomy; Hepatectomy; Humans; Infusions, Intravenous; Liver Neoplasms; Male; Oxonic Acid; Pyridines; Stomach Neoplasms; Taxoids; Tegafur | 2004 |
[Three successful case reports of advanced gastric cancer with chemotherapy].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Cisplatin; Drug Administration Schedule; Drug Combinations; Fluorouracil; Gastrectomy; Humans; Infusions, Intravenous; Liver Neoplasms; Male; Oxonic Acid; Pyridines; Stomach Neoplasms; Tegafur | 2004 |
[A case of successful treatment with combined 5-fluorouracil, adriamycin, cisplatin (FAP) therapy followed by Gemcitabine, UFT therapy and intra-arterial FAP therapy for unresectable advanced gallbladder cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Doxorubicin; Female; Fluorouracil; Gallbladder Neoplasms; Gemcitabine; Humans; Middle Aged; Tegafur; Uracil | 2004 |
[The 5-fluorouracil hepato-arterial infusion with oral UFT therapy for the hepatic and extra hepatic metastases of colorectal cancer].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Tegafur; Uracil | 2004 |
[A case report--Efficacy of combination therapy to unresectable advanced gall bladder carcinoma--palliative operation, hepatic arterial infusion therapy, and radiation therapy].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Combined Modality Therapy; Drug Combinations; Duodenal Neoplasms; Fluorouracil; Gallbladder Neoplasms; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Mitomycin; Palliative Care; Stents; Tegafur; Uracil | 2004 |
[A case of long-term survivor with multiple pulmonary metastases of HCC after hepatic resection].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Drug Combinations; Fluorouracil; Hepatectomy; Humans; Interferon-alpha; Interferon-beta; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Pyridines; Tegafur; Time Factors; Uracil | 2004 |
Immunohistochemical evaluation of thymidylate synthase (TS) and p16INK4a in advanced colorectal cancer: implication of TS expression in 5-FU-based adjuvant chemotherapy.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Chemotherapy, Adjuvant; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Drug Combinations; Female; Fluorouracil; Humans; Immunohistochemistry; Male; Middle Aged; Neoplasm Invasiveness; Postoperative Period; Rectal Neoplasms; Tegafur; Thymidylate Synthase; Uracil | 2004 |
[Two cases of gastric cancer with multiple liver metastases responding to TS-1 with hepatic arterial infusion of CDDP following low-dose 5-FU and CDDP chemotherapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Fluorouracil; Gastrectomy; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Lymph Node Excision; Male; Oxonic Acid; Pyridines; Quality of Life; Stomach Neoplasms; Tegafur | 2005 |
[A case of liver metastases from cecal cancer successfully treated with fluorouracil and folinic acid (UFT/LV)].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cecal Neoplasms; Chemotherapy, Adjuvant; Colectomy; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Male; Tegafur; Uracil | 2005 |
[Pharmacokinetic modulating chemotherapy for rectal carcinoma metastases to the liver and lung--a case report].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Rectal Neoplasms; Tegafur; Uracil | 2005 |
[Modified pharmacokinetic modulating chemotherapy for progressive gastric cancer accompanied by peritoneal dissemination].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Peritoneal Neoplasms; Stomach Neoplasms; Survival Rate; Tegafur; Uracil | 2005 |
[A case of advanced gastric cancer with bone metastasis and severe DIC responding to hypertensive subselective chemotherapy with pharmacokinetic modulating chemotherapy].
Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Signet Ring Cell; Disseminated Intravascular Coagulation; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Methotrexate; Middle Aged; Paclitaxel; Quality of Life; Stomach Neoplasms; Tegafur; Uracil | 2005 |
Effects of oral 5-fluorouracil drugs on hepatic fat content in patients with colon cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Chi-Square Distribution; Colonic Neoplasms; Fatty Liver; Female; Floxuridine; Fluorouracil; Humans; Male; Middle Aged; Retrospective Studies; Tegafur; Tomography, X-Ray Computed; Uracil | 2005 |
Correlations between antitumor activities of fluoropyrimidines and DPD activity in lung tumor xenografts.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cell Line, Tumor; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Floxuridine; Fluorouracil; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Orotate Phosphoribosyltransferase; Oxonic Acid; Pyridines; Tegafur; Thymidine Phosphorylase; Treatment Outcome; Uracil; Xenograft Model Antitumor Assays | 2005 |
[TS-1 treatment for progressive gastric cancer in a patient on chronic dialysis--assessment of dosage regimen by monitoring blood concentrations of therapeutic drugs (TDM)].
Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Area Under Curve; Drug Administration Schedule; Drug Combinations; Drug Monitoring; Fluorouracil; Gastrectomy; Humans; Kidney Failure, Chronic; Male; Oxonic Acid; Peritoneal Neoplasms; Pyridines; Renal Dialysis; Stomach Neoplasms; Tegafur | 2005 |
[Pharmacokinetics and adverse event of TS-1 administered through gastrostomy].
Topics: Deglutition Disorders; Drug Administration Schedule; Drug Combinations; Fluorouracil; Gas Chromatography-Mass Spectrometry; Gastrostomy; Humans; Informed Consent; Intubation, Gastrointestinal; Male; Middle Aged; Oropharyngeal Neoplasms; Oxonic Acid; Pyridines; Tegafur | 2005 |
Leflunomide and peripheral neuropathy: a potential interaction between uracil/tegafur and leflunomide.
Topics: Administration, Oral; Aged; Arthritis, Rheumatoid; Comorbidity; Disease Progression; Drug Administration Schedule; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Fluorouracil; Humans; Isoxazoles; Leflunomide; Male; Peripheral Nervous System Diseases; Polyneuropathies; Rectal Neoplasms; Tegafur; Time Factors; Uracil | 2005 |
[Combined chemotherapy with oral leucovorin (LV) + tegafur/uracil (UFT) and hepatic arterial infusion (HAI) therapy for liver metastasis of colorectal cancer].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Middle Aged; Tegafur; Uracil | 2005 |
Sensitive MS/MS-liquid chromatography assay for simultaneous determination of tegafur, 5-fluorouracil and 5-fluorodihydrouracil in plasma.
Topics: Chromatography, High Pressure Liquid; Fluorouracil; Humans; Mass Spectrometry; Reproducibility of Results; Tegafur; Time Factors | 2005 |
[Stage IV gastric cancer patient who underwent palliative gastrectomy showing complete response to induction therapy with methotrexate plus 5-fluorouracil and secondary treatment with oral TS-1].
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Carcinoembryonic Antigen; Carcinoma, Signet Ring Cell; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Leucovorin; Lymphatic Metastasis; Methotrexate; Oxonic Acid; Palliative Care; Pyridines; Stomach Neoplasms; Tegafur | 2005 |
Just when you thought the fluorouracil debate was over: S-1 and gastric cancer.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Infusions, Intravenous; Oxonic Acid; Pyridines; Stomach Neoplasms; Tegafur | 2005 |
Enhancement of the anti-tumor activity of S-1 by low-dose cisplatin in mice bearing the sarcoma-180 model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cisplatin; Drug Combinations; Fluorouracil; Male; Mice; Mice, Inbred Strains; Oxonic Acid; Pyridines; RNA, Neoplasm; Sarcoma 180; Tegafur; Thymidine Kinase; Uridine Triphosphate | 2005 |
Preoperative chemoradiation of locally advanced T3 rectal cancer combined with an endorectal boost.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Combined Modality Therapy; Feasibility Studies; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Radiotherapy Dosage; Rectal Neoplasms; Remission Induction; Tegafur | 2006 |
[Treatment strategy for primary gastric cancer with peritoneal dissemination].
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Combinations; Fluorouracil; Gastrectomy; Humans; Lymph Node Excision; Methotrexate; Oxonic Acid; Paclitaxel; Peritoneal Neoplasms; Pyridines; Stomach Neoplasms; Survival Rate; Tegafur | 2005 |
[Case report--postoperative continuous intraarterial infusion of small doses of 5-FU successfully controlled residual tumor and liver metastasis of stage IV gastric cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Doxorubicin; Drug Combinations; Floxuridine; Fluorouracil; Gastrectomy; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Mitomycin; Neoplasm Staging; Picibanil; Proteoglycans; Stomach Neoplasms; Tegafur; Uracil | 2005 |
[A case of colon cancer with multiple liver, lung and bone metastases successfully treated with combined weekly high-dose 5-FU (WHF) chemotherapy with UFT and CPT-11].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Lung Neoplasms; Middle Aged; Tegafur; Uracil | 2005 |
Diamine oxidase, a plasma biomarker in rats to GI tract toxicity of oral fluorouracil anti-cancer drugs.
Topics: Administration, Oral; Amine Oxidase (Copper-Containing); Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers; Body Weight; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Intestinal Mucosa; Jejunal Diseases; Male; Orotate Phosphoribosyltransferase; Oxonic Acid; Pyridines; Rats; Rats, Sprague-Dawley; Tegafur | 2006 |
[Effect of intraperitoneal chemotherapy on experimental peritoneal dissemination of gastric cancer].
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carboplatin; Cisplatin; Docetaxel; Drug Combinations; Drug Screening Assays, Antitumor; Fluorouracil; Infusions, Parenteral; Mice; Mice, Nude; Neoplasm Seeding; Oxonic Acid; Peritoneal Neoplasms; Pyridines; Stomach Neoplasms; Taxoids; Tegafur | 2005 |
[Hepatic arterial infusion (HAI) chemotherapy achieved a complete response (CR) for multiple liver metastases of colorectal cancer--two case reports].
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neoplasms; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Remission Induction; Tegafur; Uracil | 2005 |
Potassium oxonate, an enzyme inhibitor compounded in S-1, reduces the suppression of antitumor immunity induced by 5-fluorouracil.
Topics: Animals; Drug Combinations; Enzyme Inhibitors; Fluorouracil; Immunophenotyping; Interleukin-2; Killer Cells, Natural; Male; Neoplasms, Experimental; Oxonic Acid; Pyridines; Rats; Tegafur | 2006 |
[Combination therapy with TS-1].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Docetaxel; Drug Administration Schedule; Drug Combinations; Fluorouracil; Head and Neck Neoplasms; Humans; Organoplatinum Compounds; Oxonic Acid; Pyridines; Taxoids; Tegafur | 2005 |
5-Fluorouracil cardiotoxicity induced by alpha-fluoro-beta-alanine.
Topics: Aged; Antimetabolites, Antineoplastic; beta-Alanine; Cardiovascular Diseases; Colonic Neoplasms; Drug Combinations; Electrocardiography; Fluorouracil; Heart; Humans; Liver Neoplasms; Lung Neoplasms; Male; Oxonic Acid; Tegafur | 2005 |
Chemotherapy of metastatic colorectal cancer: fluorouracil plus folinic acid and irinotecan or oxaliplatin.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Camptothecin; Chemotherapy, Adjuvant; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Neoplasm Metastasis; Organoplatinum Compounds; Quinazolines; Tegafur; Thiophenes; Treatment Outcome; Uracil | 2005 |
Prognostic factors for disease-free survival in patients with T3-4 or N+ rectal cancer treated with preoperative chemoradiation therapy, surgery, and intraoperative irradiation.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Prognosis; Radiotherapy; Radiotherapy Dosage; Rectal Neoplasms; Recurrence; Sex Factors; Statistics as Topic; Tegafur | 2006 |
Effect of gastrectomy on the pharmacokinetics of 5-fluorouracil and gimeracil after oral administration of S-1.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Male; Middle Aged; Oxonic Acid; Pyridines; Stomach Neoplasms; Tegafur; Time Factors | 2006 |
Synergistic effects of docetaxel and S-1 by modulating the expression of metabolic enzymes of 5-fluorouracil in human gastric cancer cell lines.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Dihydrouracil Dehydrogenase (NADP); Docetaxel; Drug Combinations; Drug Synergism; Female; Fluorouracil; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Multienzyme Complexes; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Oxonic Acid; Stomach Neoplasms; Taxoids; Tegafur; Thymidylate Synthase; Xenograft Model Antitumor Assays | 2006 |
[Experimental chemotherapy against human esophageal carcinoma xenografts with TS-1, cisplatin and docetaxel].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Drug Combinations; Drug Synergism; Esophageal Neoplasms; Fluorouracil; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Oxonic Acid; Pyridines; Succinate Dehydrogenase; Taxoids; Tegafur; Thymidylate Synthase; Tumor Cells, Cultured | 2006 |
Guides for adjuvant treatment of colon cancer. TTD Group (Spanish Cooperative Group for Gastrointestinal Tumor Therapy).
Topics: Adenocarcinoma; Algorithms; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Colorectal Neoplasms; Deoxycytidine; Drug Administration Schedule; Fluorouracil; Humans; Leucovorin; Lymphatic Metastasis; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Randomized Controlled Trials as Topic; Risk Assessment; Tegafur; Uracil | 2006 |
Improved incidence of pT0 downstaged surgical specimens in locally advanced rectal cancer (LARC) treated with induction oxaliplatin plus 5-fluorouracil and preoperative chemoradiation.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Radiotherapy Dosage; Rectal Neoplasms; Tegafur | 2006 |
[A case of hepatic metastases of sigmoid colon cancer which completely responded to systemic l-leucovorin/5-FU therapy and oral LV/UFT combination therapy].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Male; Sigmoid Neoplasms; Tegafur; Uracil | 2006 |
TS-1 as first-line therapy for gastric linitis plastica: historical control study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Female; Fluorouracil; Humans; Linitis Plastica; Male; Methotrexate; Middle Aged; Mitomycin; Oxonic Acid; Pyridines; Retrospective Studies; Stomach Neoplasms; Survival Analysis; Tegafur | 2006 |
Simple combinations of 5-FU pathway genes predict the outcome of metastatic gastric cancer patients treated by S-1.
Topics: Adult; Aged; Drug Combinations; Drug Therapy, Combination; Female; Fluorouracil; Gene Expression; Humans; Male; Middle Aged; Neoplasm Metastasis; Oxonic Acid; Stomach Neoplasms; Survival Rate; Tegafur; Treatment Outcome | 2006 |
S-1 (TS-1) maintained complete response for approximately 10 years in a case of metastatic breast cancer.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Immunohistochemistry; Lung Neoplasms; Mastectomy, Modified Radical; Middle Aged; Neoplasm Staging; Remission Induction; Risk Assessment; Tamoxifen; Tegafur; Time Factors; Treatment Outcome | 2006 |
[Second-line chemotherapy with pharmacokinetic modulating chemotherapy for unresectable colorectal carcinoma recurrences resistant to 5-FU-based chemotherapy].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chronotherapy; Colonic Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Rectal Neoplasms; Survival Rate; Tegafur; Uracil | 2006 |
Quality of Life assessment through the EORTC questionnaires of locally advanced rectal cancer patients treated with preoperative chemo-radiotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Body Image; Emotions; Female; Fluorouracil; Follow-Up Studies; Gastrointestinal Diseases; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Preoperative Care; Quality of Life; Radiotherapy; Rectal Neoplasms; Sexual Behavior; Surveys and Questionnaires; Tegafur; Urination Disorders | 2006 |
Pharmacokinetics of S-1 in patients with peritoneal dissemination of gastric cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Biological Availability; Drug Combinations; Female; Fluorouracil; Humans; Lymph Nodes; Male; Middle Aged; Oxonic Acid; Peritoneal Neoplasms; Peritoneum; Pyridines; Stomach Neoplasms; Tegafur | 2006 |
Retrospective analysis on prognostic impact of adjuvant chemotherapy in the patients with advanced and resectable oral squamous cell carcinoma.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Mouth Neoplasms; Neck; Neoadjuvant Therapy; Neoplasm Staging; Prognosis; Proportional Hazards Models; Radiotherapy Dosage; Retrospective Studies; Survival Rate; Tegafur; Uracil | 2006 |
[A case of long-term survival of gastric cancer with peritoneal metastasis effectively treated by TS-1 and paclitaxel (PTX) combination therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Constriction, Pathologic; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Middle Aged; Oxonic Acid; Paclitaxel; Peritoneal Neoplasms; Sigmoid Diseases; Stomach Neoplasms; Tegafur | 2006 |
S-1, an oral fluoropyrimidine, enhances radiation response of DLD-1/FU human colon cancer xenografts resistant to 5-FU.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colorectal Neoplasms; Drug Combinations; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Oxonic Acid; Radiation-Sensitizing Agents; Tegafur; Xenograft Model Antitumor Assays | 2006 |
Schedule-dependent therapeutic effects of gemcitabine combined with uracil-tegafur in a human pancreatic cancer xenograft model.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Administration Schedule; Drug Combinations; Equilibrative Nucleoside Transporter 1; Fluorouracil; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; RNA, Messenger; Tegafur; Uracil; Xenograft Model Antitumor Assays | 2006 |
Tegafur and 5-fluorouracil pelvic tissue concentrations in rectal cancer patients receiving preoperative chemoradiation.
Topics: Adipose Tissue; Adult; Aged; Antimetabolites, Antineoplastic; Female; Fluorouracil; Humans; Intestinal Mucosa; Male; Middle Aged; Neoplasm, Residual; Pelvis; Rectal Neoplasms; Rectum; Tegafur; Treatment Outcome | 2006 |
Evaluations of biomarkers associated with 5-FU sensitivity for non-small-cell lung cancer patients postoperatively treated with UFT.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Female; Fluorouracil; Humans; Immunohistochemistry; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Survival Analysis; Tegafur; Uracil | 2006 |
[Antitumor activity and function of S-1, a new oral tegafur-based formulation].
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Mice; Neoplasm Transplantation; Neoplasms; Oxonic Acid; Pharmaceutical Preparations; Rats; Sarcoma, Yoshida; Tegafur; Uracil | 2006 |
[Plasma concentrations of 5-fluorouracil and F-beta-alanine following oral administration of S-1, a dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine, as compared with protracted venous infusion of 5-fluorouracil].
Topics: beta-Alanine; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Fluorouracil; Humans; Infusions, Intravenous; Kidney; Oxonic Acid; Stomach Neoplasms; Tegafur; Uracil | 2006 |
[Long-term repeatable chemotherapy for patients with advanced pancreatic cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Paclitaxel; Pancreatic Neoplasms; Quality of Life; Remission Induction; Survival Rate; Tegafur | 2006 |
[A case of advanced esophageal cancer with suspected tracheoesophageal fistula that responded to chemoradiotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Esophageal Neoplasms; Fluorouracil; Humans; Male; Middle Aged; Quality of Life; Radiotherapy Dosage; Remission Induction; Stents; Tegafur; Trachea; Tracheal Stenosis; Tracheoesophageal Fistula; Uracil | 2006 |
A case of early relapsed multiple lung metastases after esophagectomy successfully treated with S-1/cisplatin therapy after docetaxel/5-fluorouracil/cisplatin therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Docetaxel; Drug Combinations; Esophageal Neoplasms; Esophagectomy; Fluorouracil; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Oxonic Acid; Recurrence; Taxoids; Tegafur | 2006 |
[A case of advanced gastric cancer with liver metastasis completely responding to CPT-11+low-dose 5-FU+CDDP chemotherapy].
Topics: Adenocarcinoma; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cardia; Cisplatin; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Oxonic Acid; Remission Induction; Stomach Neoplasms; Tegafur | 2006 |
[A case of effective multidisciplinary treatment with hepatic resection for synchronous multiple liver metastases from rectal cancer].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Mitomycin; Quality of Life; Rectal Neoplasms; Remission Induction; Tegafur; Uracil | 2006 |
[Partial response of liver metastasis from colon cancer following intermittent oral administration of TS-1 after intra-hepatic arterial single injection of CDDP, doxorubicin and 5-FU].
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colectomy; Colonic Neoplasms; Doxorubicin; Drug Administration Routes; Drug Combinations; Fluorouracil; Humans; Injections, Intra-Arterial; Liver Neoplasms; Male; Oxonic Acid; Quality of Life; Remission Induction; Tegafur | 2006 |
[Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma providing a good QOL].
Topics: Aged; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cisplatin; Epirubicin; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Quality of Life; Tegafur; Tomography, X-Ray Computed; Uracil | 2006 |
[A case of colon cancer liver metastases treated by combined therapies].
Topics: Antineoplastic Combined Chemotherapy Protocols; Catheter Ablation; Chemotherapy, Adjuvant; Colon, Sigmoid; Combined Modality Therapy; Floxuridine; Fluorouracil; Hepatectomy; Humans; Jaundice, Obstructive; Leucovorin; Liver Neoplasms; Lymph Node Excision; Male; Middle Aged; Sigmoid Neoplasms; Stents; Tegafur | 2006 |
[A case report of advanced gastric cancer with carcinomatous ascites successfully treated by outpatient chemotherapy].
Topics: Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Ascites; Ascitic Fluid; Cisplatin; Docetaxel; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Male; Middle Aged; Oxonic Acid; Paclitaxel; Peritoneal Neoplasms; Quality of Life; Stomach Neoplasms; Taxoids; Tegafur | 2007 |
Expression of phosphorylated Akt (pAkt) in gastric carcinoma predicts prognosis and efficacy of chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouracil; Humans; Male; Middle Aged; Phosphorylation; Predictive Value of Tests; Prognosis; Proto-Oncogene Proteins c-akt; Stomach Neoplasms; Survival Analysis; Tegafur; Tumor Suppressor Protein p53 | 2007 |
[A resected case of squamous cell carcinoma of the breast successfully treated by FU plus cisplatin (CDDP) adjuvant therapy against recurrent metastases].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Mastectomy; Neoplasm Invasiveness; Oxonic Acid; Skin Neoplasms; Tegafur; Uracil | 2007 |
[A long survival case of sigmoid colon cancer patient with initially unresectable hepatic metastases].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Middle Aged; Neoadjuvant Therapy; Second-Look Surgery; Sigmoid Neoplasms; Survivors; Tegafur; Uracil | 2007 |
The clinical and economic benefits of capecitabine and tegafur with uracil in metastatic colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Tegafur; United Kingdom; Uracil | 2007 |
Peritoneal dissemination of hepatocellular carcinoma treated with a combination therapy of interferon-alpha-2b and oral tegafur/uracil.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Fatigue; Fluorouracil; Humans; Injections, Intravenous; Injections, Subcutaneous; Interferon alpha-2; Interferon-alpha; Liver Neoplasms; Male; Nausea; Peritoneal Neoplasms; Recombinant Proteins; Retreatment; Tegafur; Tomography, X-Ray Computed; Treatment Outcome | 2007 |
[Comparison the standard therapies of gastric cancer in Japan with those in the West].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Drug Combinations; Europe; Fluorouracil; Gastrectomy; Humans; Japan; Lymph Node Excision; Mitomycin; Neoplasm Staging; Practice Guidelines as Topic; Stomach Neoplasms; Survival Rate; Tegafur; United States; Uracil | 2007 |
[Nedaplatin (NDP)-combination therapy (NDP/5-FU,NDP/S-1) for oral cancer].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Infusions, Intravenous; Leukopenia; Male; Middle Aged; Mouth Neoplasms; Nausea; Organoplatinum Compounds; Oxonic Acid; Tegafur; Thrombocytopenia; Vomiting, Anticipatory | 2007 |
Expression of orotate phosphoribosyl transferase in human pancreatic cancer: implication for the efficacy of uracil and tegafur-based adjuvant chemotherapy.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; Carcinoma, Papillary; Chemotherapy, Adjuvant; Cyclophosphamide; Deoxycytidine; Female; Fluorouracil; Gemcitabine; Humans; Male; Middle Aged; Neoplasm Staging; Orotate Phosphoribosyltransferase; Pancreatic Neoplasms; Prognosis; Survival Rate; Tegafur | 2007 |
[Pharmacokinetics of 5-FU after S-1 oral administration for adjuvant chemotherapy in gastric cancer patients].
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Stomach Neoplasms; Tegafur | 2007 |
[Long survival of a colon cancer case with multiple liver metastases cured by multidisciplinary therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Catheter Ablation; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Fluorouracil; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Organoplatinum Compounds; Oxonic Acid; Sigmoid Neoplasms; Survivors; Tegafur | 2007 |
[Therapeutic strategy for type 4 gastric cancer from the clinical oncologist standpoint].
Topics: Adenocarcinoma, Scirrhous; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Male; Methotrexate; Middle Aged; Oxonic Acid; Paclitaxel; Prognosis; Stomach Neoplasms; Survival Rate; Tegafur | 2007 |
[Evaluation of combination therapy of high-dose toremifene and oral chemotherapy].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Cyclophosphamide; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Floxuridine; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Quality of Life; Skin Neoplasms; Tegafur; Toremifene | 2007 |
Delayed leukoencephalopathy with stroke-like presentation in chemotherapy recipients.
Topics: Adult; Aged; Antineoplastic Agents; Brain; Brain Edema; Capecitabine; Dementia, Vascular; Deoxycytidine; Diffusion Magnetic Resonance Imaging; Energy Metabolism; Female; Fluorouracil; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Infusions, Intravenous; Injections, Spinal; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neoplasms; Nerve Fibers, Myelinated; Neurologic Examination; Registries; Remission, Spontaneous; Stroke; Tegafur | 2008 |
Alternative pharmacokinetics of S-1 components, 5-fluorouracil, dihydrofluorouracil and alpha-fluoro-beta-alanine after oral administration of S-1 following total gastrectomy.
Topics: Administration, Oral; Adult; Aged; Area Under Curve; beta-Alanine; Drug Combinations; Fluorouracil; Gastrectomy; Humans; Middle Aged; Oxonic Acid; Stomach Neoplasms; Tegafur | 2007 |
[An elderly case of advanced cervical esophageal cancer successfully treated with UFT after chemoradiotherapy with docetaxel/5-FU/CDDP].
Topics: Aged, 80 and over; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Docetaxel; Drug Administration Schedule; Drug Combinations; Esophageal Neoplasms; Female; Fluorouracil; Humans; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Quality of Health Care; Taxoids; Tegafur; Uracil | 2007 |
Epidermal growth factor receptor mutation status and adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; ErbB Receptors; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Mutation; Retrospective Studies; Survival Rate; Tegafur; Tumor Cells, Cultured; Uracil | 2007 |
[The fourth report from Sapporo Tsukisamu Hospital - chemotherapy and its regimen as second choice for patients with early gastric cancer].
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Retrospective Studies; Stomach Neoplasms; Survival Rate; Tegafur; Uracil | 2007 |
[A case of metastatic rectal cancer showing a sustained complete response to chemotherapy with FOLFIRI followed by UFT].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Fluorouracil; Humans; Leucovorin; Neoplasm Metastasis; Rectal Neoplasms; Tegafur; Uracil | 2007 |
Synergistic antitumor effect of combined 5-fluorouracil (5-FU) with 5-chloro-2,4-dihydroxypyridine on 5-FU-resistant gastric cancer cells: possible role of a dihydropyrimidine dehydrogenase-independent mechanism.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Dihydrouracil Dehydrogenase (NADP); Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Oxonic Acid; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Tegafur; Thymidylate Synthase | 2007 |
A multi-center retrospective analysis of survival benefits of chemotherapy for unresectable biliary tract cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Cisplatin; Deoxycytidine; Doxorubicin; Drug Combinations; Female; Fluorouracil; Gemcitabine; Humans; Male; Middle Aged; Mitomycin; Oxonic Acid; Proportional Hazards Models; Retrospective Studies; Survival Analysis; Tegafur | 2007 |
Improved determination of 5-fluorouracil and its prodrug tegafur in pharmaceuticals by large-volume sample stacking in CE.
Topics: Electrophoresis, Capillary; Fluorouracil; Molecular Structure; Pharmaceutical Preparations; Prodrugs; Tegafur | 2007 |
[Two cases of stage IV gastric cancer who underwent total gastrectomy and achieved long-term survival by sequential chemotherapy].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Immunosuppressive Agents; Irinotecan; Male; Methotrexate; Middle Aged; Oxonic Acid; Paclitaxel; Stomach Neoplasms; Tegafur | 2007 |
[A case report--combination chemotherapy with oral UFT and CPT-11, 5-FU, l-LV by hepatic arterial infusion for multiple hepatic metastasis from sigmoid colon cancer].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Middle Aged; Sigmoid Neoplasms; Tegafur; Uracil | 2007 |
UFT as maintenance therapy in patients with advanced colorectal cancer responsive to the FOLFOX4 regimen.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease Progression; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Quality of Life; Remission Induction; Tegafur; Uracil | 2007 |
The CYP2A6*4 allele is determinant of S-1 pharmacokinetics in Japanese patients with non-small-cell lung cancer.
Topics: Adult; Aged; Alleles; Antimetabolites, Antineoplastic; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Asian People; Carcinoma, Non-Small-Cell Lung; Cytochrome P-450 CYP2A6; Drug Combinations; Female; Fluorouracil; Genotype; Humans; Lung Neoplasms; Male; Middle Aged; Mixed Function Oxygenases; Oxonic Acid; Smoking; Tegafur | 2008 |
Study of carbonyl iron/poly(butylcyanoacrylate) (core/shell) particles as anticancer drug delivery systems Loading and release properties.
Topics: Antimetabolites, Antineoplastic; Drug Delivery Systems; Enbucrilate; Fluorouracil; Hydrogen-Ion Concentration; Iron Compounds; Nanoparticles; Tegafur | 2008 |
Oral treatment for gastric cancer: new choices, better choices?
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Clinical Trials, Phase III as Topic; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Japan; Oxonic Acid; Randomized Controlled Trials as Topic; Stomach Neoplasms; Survival Rate; Tegafur | 2008 |
Sustained release of antineoplastic drugs from chitosan-reinforced alginate microparticle drug delivery systems.
Topics: Alginates; Antimetabolites, Antineoplastic; Antineoplastic Agents; Chemical Phenomena; Chemistry, Physical; Chitosan; Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; Excipients; Fluorouracil; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Polysaccharides; Tegafur | 2008 |
The unanswered question: what is the determinant of S-1 pharmacokinetics?
Topics: Alleles; Antimetabolites, Antineoplastic; Aryl Hydrocarbon Hydroxylases; Asian People; Body Size; Carcinoma, Non-Small-Cell Lung; Cytochrome P-450 CYP2A6; Drug Combinations; Fluorouracil; Humans; Lung Neoplasms; Oxonic Acid; Tegafur | 2008 |
[Complete response in a case of advanced esophageal cancer treated with docetaxel/5-FU/CDDPand S-1/docetaxel as neoadjuvant chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Drug Combinations; Esophageal Neoplasms; Female; Fluorouracil; Gastroscopy; Humans; Middle Aged; Neoadjuvant Therapy; Oxonic Acid; Taxoids; Tegafur; Tomography, X-Ray Computed | 2008 |
Anti-angiogenic effect of 5-Fluorouracil-based drugs against human colon cancer xenografts.
Topics: Angiogenesis Inhibitors; Animals; Capecitabine; Colonic Neoplasms; Deoxycytidine; Drug Combinations; Fluorouracil; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Oxonic Acid; Tegafur; Thrombospondin 1; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2008 |
5-Fluorouracil incorporated into the tissue RNA of human and rat bladder carcinoma after administration of 1-(2-tetrahydrofuryl)-5-fluorouracil combined with uracil.
Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Rats; Rats, Inbred F344; RNA, Neoplasm; Tegafur; Uracil; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays | 2008 |
[A case of advanced gastric cancer with peritoneal metastasis successfully treated over 19 months with postoperative chemotherapy after non-curative surgery].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Irinotecan; Methotrexate; Oxonic Acid; Paclitaxel; Peritoneal Neoplasms; Stomach Neoplasms; Tegafur | 2008 |
Effects of combined administration of DPD-inhibitory oral fluoropyrimidine, S-1, plus paclitaxel on gene expressions of fluoropyrimidine metabolism-related enzymes in human gastric xenografts.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Gene Expression; Humans; Male; Mice; Mice, Inbred BALB C; Orotate Phosphoribosyltransferase; Oxonic Acid; Paclitaxel; Stomach Neoplasms; Tegafur; Thymidine Phosphorylase; Thymidylate Synthase; Uridine Phosphorylase; Xenograft Model Antitumor Assays | 2008 |
Additive effects of oral fluoropyrimidine derivative S-1 and radiation on human hypopharyngeal cancer xenografts.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Combined Modality Therapy; Drug Combinations; Fluorouracil; Humans; Hypopharyngeal Neoplasms; Male; Mice; Mice, Nude; Oxonic Acid; Tegafur; Tumor Burden; Xenograft Model Antitumor Assays | 2008 |
Is there an optimal chemotherapy regimen for the treatment of advanced gastric cancer that will provide a platform for the introduction of new biological agents?
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Clinical Trials, Phase III as Topic; Deoxycytidine; Docetaxel; Drug Combinations; Fluorouracil; Humans; Immunologic Factors; Irinotecan; Meta-Analysis as Topic; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Randomized Controlled Trials as Topic; Stomach Neoplasms; Taxoids; Tegafur | 2008 |
[Case of gastric cancer with isolated brain metastasis successfully managed by gamma knife radiotherapy and chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Combined Modality Therapy; Drug Combinations; Fluorouracil; Humans; Male; Middle Aged; Oxonic Acid; Radiosurgery; Stomach Neoplasms; Tegafur; Treatment Outcome | 2008 |
Immunochemotherapy with PSK and fluoropyrimidines improves long-term prognosis for curatively resected colorectal cancer.
Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Combined Modality Therapy; Drug Combinations; Female; Floxuridine; Fluorouracil; Humans; Immunotherapy; Kaplan-Meier Estimate; Male; Middle Aged; Prognosis; Proportional Hazards Models; Proteoglycans; Retrospective Studies; Tegafur; Uracil | 2008 |
Efficacy of S-1 in heavily pretreated patients with metastatic breast cancer: cross-resistance to capecitabine.
Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antimetabolites, Antineoplastic; Bone Neoplasms; Breast Neoplasms; Bridged-Ring Compounds; Capecitabine; Deoxycytidine; Drug Combinations; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Oxonic Acid; Pleural Neoplasms; Prognosis; Retrospective Studies; Survival Rate; Taxoids; Tegafur; Treatment Outcome | 2009 |
[Two cases of squamous cell carcinoma of upper urinary tract with hypercalcemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Fatal Outcome; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Hypercalcemia; Kidney Neoplasms; Kidney Pelvis; Male; Middle Aged; Neoplasm Recurrence, Local; Parathyroid Hormone-Related Protein; Radiotherapy; Tegafur; Uracil; Ureteral Neoplasms | 2008 |
Oral fluoropyrimidines (capecitabine or S-1) and cisplatin as first line treatment in elderly patients with advanced gastric cancer: a retrospective study.
Topics: Adenocarcinoma; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cisplatin; Combined Modality Therapy; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Maximum Tolerated Dose; Neoplasm Recurrence, Local; Neoplasm Staging; Oxonic Acid; Prognosis; Retrospective Studies; Stomach Neoplasms; Tegafur | 2009 |
[A case of metastatic lung and liver tumors from rectal cancer treated with oral UFT and CPT-11 by hepatic arterial infusion followed by FOLFOX and FOLFIRI].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Fluorouracil; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Rectal Neoplasms; Tegafur; Tomography, X-Ray Computed; Uracil | 2008 |
Relationships of insulin-like growth factor-1 receptor and epidermal growth factor receptor expression to clinical outcomes in patients with colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Colorectal Neoplasms; ErbB Receptors; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Middle Aged; Prognosis; Receptor, IGF Type 1; Rectal Neoplasms; Tegafur; Treatment Outcome | 2009 |
Development history and concept of an oral anticancer agent S-1 (TS-1): its clinical usefulness and future vistas.
Topics: Animals; Antimetabolites, Antineoplastic; Drug Combinations; Fluorouracil; History, 20th Century; History, 21st Century; Humans; Neoplasms; Oxonic Acid; Tegafur | 2009 |
Gemcitabine-based versus fluoropyrimidine-based chemotherapy with or without platinum in unresectable biliary tract cancer: a retrospective study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Capecitabine; Cisplatin; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Gemcitabine; Humans; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Palliative Care; Pyrimidinones; Retrospective Studies; Tegafur; Treatment Outcome; Uracil | 2008 |
Comparison of alternate-day versus consecutive-day treatment with S-1: assessment of tumor growth inhibition and toxicity reduction in gastric cancer cell lines in vitro and in vivo.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Bone Marrow Diseases; Cell Proliferation; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Gastrointestinal Tract; Humans; In Vitro Techniques; Mice; Mice, Inbred BALB C; Mice, Nude; Oxonic Acid; Stomach Neoplasms; Survival Rate; Tegafur; Tetrazolium Salts; Tumor Cells, Cultured | 2008 |
Successful treatment of advanced gallbladder cancer with an anticancer drug S-1: assessment based on intratumoral gene.
Topics: Antimetabolites, Antineoplastic; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Female; Fluorouracil; Gallbladder Neoplasms; Humans; Middle Aged; Oxonic Acid; Tegafur; Tomography, X-Ray Computed | 2008 |
The efficacy and safety of concurrent chemoradiotherapy for maxillary sinus squamous cell carcinoma patients.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Maxillary Sinus; Methotrexate; Middle Aged; Neoadjuvant Therapy; Organ Preservation; Paranasal Sinus Neoplasms; Retrospective Studies; Tegafur; Treatment Outcome; Uracil | 2009 |
[Our experiences of preoperative chemo-radiotherapy for T4 primary rectal cancer].
Topics: Antineoplastic Agents; Drug Combinations; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Oxonic Acid; Rectal Neoplasms; Tegafur | 2008 |
[Complete response of advanced rectal cancer with combined therapy of S-1 + chemo-radiation plus FOLFIRI--a case report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Drug Combinations; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Proctoscopy; Rectal Neoplasms; Remission Induction; Tegafur; Tomography, X-Ray Computed | 2008 |
Laparoscopic resection of extraperitoneal rectal cancer: a comparative analysis with open resection.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease Progression; Disease-Free Survival; Elective Surgical Procedures; Female; Fluorouracil; Follow-Up Studies; Humans; Laparoscopy; Laparotomy; Levamisole; Male; Middle Aged; Neoplasm Invasiveness; Postoperative Complications; Prospective Studies; Radiotherapy, Adjuvant; Rectal Neoplasms; Tegafur; Treatment Outcome | 2009 |
Addition of S-1 to the epidermal growth factor receptor inhibitor gefitinib overcomes gefitinib resistance in non-small cell lung cancer cell lines with MET amplification.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Drug Combinations; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; E2F1 Transcription Factor; ErbB Receptors; Fluorouracil; Gefitinib; Gene Amplification; Genes, erbB-1; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Mutation; Oxonic Acid; Proto-Oncogene Mas; Proto-Oncogene Proteins c-met; Quinazolines; Tegafur; Thymidylate Synthase | 2009 |
Pharmacokinetic study of S-1.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Anti-Ulcer Agents; Antimetabolites, Antineoplastic; Area Under Curve; beta-Alanine; Biological Availability; Clinical Trials as Topic; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Fasting; Fluorouracil; Food; Gastric Acidity Determination; Half-Life; Humans; Hydrogen-Ion Concentration; Oxonic Acid; Pantoprazole; Pyridines; Tegafur; Triazines; Uracil | 2009 |
Activity of S-1 in advanced or recurrent gastric cancer patients after failure of prior chemotherapy, including irinotecan + cisplatin or fluorouracil (except S-1).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Combinations; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Retrospective Studies; Stomach Neoplasms; Tegafur | 2009 |
Experimental study of combination therapy with S-1 against pancreatic cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Deoxycytidine; Doxorubicin; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Gemcitabine; Humans; Inhibitory Concentration 50; Irinotecan; Mice; Mice, Inbred BALB C; Mitomycin; Oxonic Acid; Paclitaxel; Pancreatic Neoplasms; Pyridines; Tegafur; Xenograft Model Antitumor Assays | 2009 |
Pharmacokinetics of 5-fluorouracil in elderly Japanese patients with cancer treated with S-1 (a combination of tegafur and dihydropyrimidine dehydrogenase inhibitor 5-chloro-2,4-dihydroxypyridine).
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asian People; Dihydrouracil Dehydrogenase (NADP); Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Fluorouracil; Humans; Metabolic Clearance Rate; Neoplasms; Pyridines; Tegafur | 2009 |
Effects of oral administration of S-1 on the pharmacokinetics of SN-38, irinotecan active metabolite, in patients with advanced colorectal cancer.
Topics: Administration, Oral; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Oxonic Acid; Prodrugs; Tegafur | 2009 |
A micro cell culture analog (microCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs.
Topics: Antimetabolites, Antineoplastic; Cell Culture Techniques; Cell Line; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Equipment Design; Fluorouracil; Granulocyte Precursor Cells; HCT116 Cells; Humans; Hydrogels; Liver; Microfluidic Analytical Techniques; Reproducibility of Results; Tegafur | 2009 |
Vascular endothelial growth factor receptor expression as a prognostic marker for survival in colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Immunoenzyme Techniques; Leucovorin; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Prognosis; Retrospective Studies; Survival Rate; Tegafur; Uracil; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factor Receptor-3 | 2009 |
Postoperative chemotherapy after neoadjuvant chemoradiation and surgery for rectal cancer: is it essential for patients with ypT0-2N0?
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Floxuridine; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Rectal Neoplasms; Retrospective Studies; Tegafur; Uracil | 2009 |
[Impact of adjuvant chemotherapy duration on 3-year disease-free survival of colorectal carcinoma patients after radical resection].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Signet Ring Cell; Chemotherapy, Adjuvant; Colorectal Neoplasms; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Lymphatic Metastasis; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Sex Factors; Tegafur | 2009 |
The effect of neoadjuvant therapy on the 5-fluorouracil metabolic and relative enzymes of oral squamous cell carcinoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Humans; Male; Middle Aged; Mouth Neoplasms; Neoadjuvant Therapy; Orotate Phosphoribosyltransferase; Tegafur; Thymidine Phosphorylase; Thymidylate Synthase; Uracil | 2009 |
Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy.
Topics: AC133 Antigen; Adult; Aged; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Glycoproteins; Humans; Immunoenzyme Techniques; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm, Residual; Octamer Transcription Factor-3; Peptides; Prognosis; Radiotherapy Dosage; Rectal Neoplasms; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; SOXB1 Transcription Factors; Survival Rate; Tegafur; Tumor Cells, Cultured; Uracil | 2009 |
The necessity of chemotherapy in T3N0M0 colon cancer without risk factors.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colonic Neoplasms; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Proportional Hazards Models; Retrospective Studies; Risk Factors; Survival Rate; Tegafur; Treatment Outcome; Uracil | 2009 |
[A case of simultaneous bilateral metastatic ovarian tumor of colon cancer followed by FOLFOX4 Regimen and oral tegafur/uracil+oral leucovorin after R0 operation].
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Colonic Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Organoplatinum Compounds; Ovarian Neoplasms; Tegafur; Uracil; Vitamin B Complex | 2009 |
Treatment of gastric cancer in Asia: the missing link.
Topics: Adenocarcinoma; Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Japan; Oxonic Acid; Patient Selection; Risk Assessment; Stomach Neoplasms; Tegafur; Time Factors; Treatment Outcome | 2009 |
[Complete remission with FLEP chemotherapy for multiple liver metastasis from alpha-fetoprotein-producing gastric cancer--report of a case].
Topics: Adenocarcinoma; alpha-Fetoproteins; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Drug Combinations; Etoposide; Fluorouracil; Gastrectomy; Humans; Immunohistochemistry; Leucovorin; Liver Neoplasms; Male; Middle Aged; Oxonic Acid; Remission Induction; Stomach Neoplasms; Tegafur | 2009 |
Effect of dimethylnitrosamine-induced liver dysfunction on the pharmacokinetics of 5-fluorouracil after administration of S-1, an antitumour drug, to rats.
Topics: Animals; Antineoplastic Agents; Area Under Curve; Chemical and Drug Induced Liver Injury; Dihydrouracil Dehydrogenase (NADP); Dimethylnitrosamine; Drug Combinations; Fluorouracil; Kidney; Liver; Liver Diseases; Male; Oxonic Acid; Rats; Rats, Sprague-Dawley; Tegafur | 2009 |
A retrospective comparison of concurrent 5-fluorouracil or oral UFT in postoperative chemoradiation for gastric adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Fluorouracil; Gastrectomy; Humans; Male; Middle Aged; Radiotherapy, Adjuvant; Retrospective Studies; Stomach Neoplasms; Tegafur; Uracil | 2010 |
[A Case of gastric endocrine cell carcinoma successfully treated by FU plus irinotecan(CPT-11)adjuvant therapy against recurrent metastases].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Fluorouracil; Gastrectomy; Humans; Irinotecan; Lymph Node Excision; Male; Neoplasm Metastasis; Stomach Neoplasms; Tegafur; Uracil | 2009 |
[Assessment of chemoradiation therapy for advanced rectal cancer invaded the pelvic organ].
Topics: Adenocarcinoma, Mucinous; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; Humans; Male; Oxonic Acid; Pelvis; Rectal Neoplasms; Tegafur | 2009 |
[A case of advanced right colonic cancer successfully treated by surgery and post operative chemotherapy].
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Combined Modality Therapy; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Lymph Node Excision; Lymphatic Metastasis; Male; Middle Aged; Organoplatinum Compounds; Oxonic Acid; Postoperative Period; Tegafur | 2009 |
[A case of long-term survival of unresectable-advanced gastric cancer due to chemotherapy].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Combinations; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Oxonic Acid; Stomach Neoplasms; Tegafur | 2009 |
[A case of successful multimodal treatment for combined hepatocellular and cholangiocarcinoma with portal venous tumor thrombus].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Cholangiocarcinoma; Combined Modality Therapy; Drug Combinations; Fluorouracil; Hepatectomy; Humans; Interferons; Liver Neoplasms; Male; Neoplastic Cells, Circulating; Oxonic Acid; Tegafur | 2009 |
[A case of stage IV breast cancer responding to S-1 therapy after FEC and PTX therapies].
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal; Cyclophosphamide; Drug Combinations; Epirubicin; Female; Fluorouracil; Humans; Oxonic Acid; Paclitaxel; Pentoxifylline; Quality of Life; Tegafur; Treatment Outcome | 2009 |
Safety, efficacy and pharmacokinetics of S-1 in a hemodialysis patient with advanced gastric cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Area Under Curve; Drug Combinations; Fluorouracil; Humans; Male; Oxonic Acid; Renal Dialysis; Stomach Neoplasms; Tegafur; Treatment Outcome | 2010 |
[Liver metastasis from sigmoid colon cancer showed a complete response to S-1 after recurrence with FOLFOX6 treatment].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Sigmoid Neoplasms; Tegafur | 2010 |
Determination of tegafur, 5-fluorouracil, gimeracil and oxonic acid in human plasma using liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, Liquid; Fluorouracil; Humans; Oxonic Acid; Pyridines; Reproducibility of Results; Tandem Mass Spectrometry; Tegafur | 2010 |
Plasma pharmacokinetics after combined therapy of gemcitabine and oral S-1 for unresectable pancreatic cancer.
Topics: Administration, Oral; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Drug Combinations; Drug Interactions; Fluorouracil; Gemcitabine; Humans; Mice; Mice, Nude; Middle Aged; Oxonic Acid; Pancreatic Neoplasms; Tegafur; Treatment Outcome; Xenograft Model Antitumor Assays | 2010 |
[A case of colon cancer with multiple liver metastases responding ot S-1 as third-line treatment following FOLFIRI and FOLFOX].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Camptothecin; Carcinoembryonic Antigen; Colonic Neoplasms; Drug Combinations; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Male; Organoplatinum Compounds; Oxonic Acid; Salvage Therapy; Tegafur; Tomography, X-Ray Computed | 2010 |
Histone deacetylase inhibitor enhances sensitivity of non-small-cell lung cancer cells to 5-FU/S-1 via down-regulation of thymidylate synthase expression and up-regulation of p21(waf1/cip1) expression.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Drug Combinations; E2F1 Transcription Factor; Fluorouracil; Gene Expression Regulation; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; Oxonic Acid; Retinoblastoma Protein; RNA, Messenger; Tegafur; Thymidylate Synthase; Vorinostat | 2010 |
Synergistic antitumor effect of S-1 and HER2-targeting agents in gastric cancer with HER2 amplification.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Drug Combinations; Drug Delivery Systems; Drug Synergism; Fluorouracil; Gene Amplification; Humans; Lapatinib; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Oxonic Acid; Quinazolines; Receptor, ErbB-2; Stomach Neoplasms; Tegafur; Trastuzumab; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2010 |
Formation pathways of gamma-butyrolactone from the furan ring of tegafur during its conversion to 5-fluorouracil.
Topics: 4-Butyrolactone; Aldehydes; Aryl Hydrocarbon Hydroxylases; Butanols; Cytochrome P-450 CYP2A6; Cytosol; DNA, Complementary; Fluorouracil; Furans; Humans; Liver; Microsomes, Liver; Phenylhydrazines; Sodium Oxybate; Tegafur; Thymidine Phosphorylase | 2010 |
Characterization of a novel lymph node metastasis model from human colonic cancer and its preclinical use for comparison of anti-metastatic efficacy between oral S-1 and UFT/ LV.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic Neoplasms; Drug Combinations; Drug Evaluation, Preclinical; Fluorouracil; Humans; Leucovorin; Lymphatic Metastasis; Male; Mice; Middle Aged; Oxonic Acid; Tegafur; Uracil; Xenograft Model Antitumor Assays | 2010 |
Circulating lymphocyte number has a positive association with tumor response in neoadjuvant chemoradiotherapy for advanced rectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Lymphocyte Count; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Oxonic Acid; Radiotherapy, Adjuvant; Rectal Neoplasms; Retrospective Studies; Survival Rate; Tegafur; Treatment Outcome; Uracil | 2010 |
Enhanced anticancer effect of the combination of BIBW2992 and thymidylate synthase-targeted agents in non-small cell lung cancer with the T790M mutation of epidermal growth factor receptor.
Topics: Afatinib; Amino Acid Substitution; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Drug Combinations; Drug Resistance, Neoplasm; Drug Synergism; E2F1 Transcription Factor; ErbB Receptors; Fluorouracil; Gefitinib; Glutamates; Guanine; Humans; Lung Neoplasms; Mice; Mutation; Oxonic Acid; Pemetrexed; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Mas; Quinazolines; Tegafur; Thymidylate Synthase; Xenograft Model Antitumor Assays | 2010 |
A quantitative evaluation of the determinant proteins for S-1 responsiveness in a biopsy specimen assists in patient selection to neoadjuvant therapy in cases of advanced gastric cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmacological; Biomarkers, Tumor; Biopsy; Carcinoma; Disease Progression; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Oxonic Acid; Patient Selection; Predictive Value of Tests; Prognosis; Retrospective Studies; Specimen Handling; Stomach Neoplasms; Tegafur | 2010 |
PharmGKB summary: fluoropyrimidine pathways.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Databases, Factual; Deoxycytidine; Fluorouracil; Genome, Human; Humans; Pharmacogenetics; Tegafur | 2011 |
Effects of lentinan alone and in combination with fluoropyrimidine anticancer agent on growth of human oral squamous cell carcinoma in vitro and in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Combinations; Female; Fluorouracil; Humans; Lentinan; Mice; Mice, Nude; Mouth Neoplasms; Oxonic Acid; Tegafur; Xenograft Model Antitumor Assays | 2010 |
Clinical results of definitive chemoradiotherapy for patients with synchronous head and neck squamous cell carcinoma and esophageal cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinoma, Squamous Cell; Cisplatin; Cohort Studies; Combined Modality Therapy; Esophageal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Neoplasms, Multiple Primary; Oxonic Acid; Pyridines; Remission Induction; Retrospective Studies; Survival Rate; Tegafur; Treatment Outcome | 2011 |
[Effect of pylorus-preserving pancreaticoduodenectomy on serum levels of 5-fluorouracil during S-1 treatment for pancreaticobiliary malignancy].
Topics: Aged; Antimetabolites, Antineoplastic; Biliary Tract Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Oxonic Acid; Pancreatic Neoplasms; Pancreaticoduodenectomy; Tegafur | 2010 |
Oral fluoropyrimidine may augment the efficacy of aromatase inhibitor via the down-regulation of estrogen receptor in estrogen-responsive breast cancer xenografts.
Topics: Anastrozole; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Blotting, Western; Breast Neoplasms; Cell Proliferation; Doxorubicin; Drug Combinations; Estrogen Receptor alpha; Estrogens; Female; Fluorouracil; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Oxonic Acid; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tegafur; Transplantation, Heterologous; Triazoles; Tumor Cells, Cultured; Uracil | 2011 |
Irinotecan overcomes the resistance to 5-fluorouracil in human colon cancer xenografts by down-regulation of intratumoral thymidylate synthase.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Camptothecin; Colonic Neoplasms; Down-Regulation; Drug Combinations; Drug Resistance, Neoplasm; Fluorouracil; Humans; Irinotecan; Mice; Mice, Nude; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Prodrugs; Tegafur; Thymidylate Synthase; Xenograft Model Antitumor Assays | 2010 |
S-1 for advanced colorectal cancer: do we need another oral fluorouracil prodrug?
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Fluorouracil; Humans; Oxonic Acid; Prodrugs; Randomized Controlled Trials as Topic; Tegafur | 2010 |
A predictive factor for the response to S-1 plus cisplatin in gastric cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Cisplatin; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Orotate Phosphoribosyltransferase; Oxonic Acid; Stomach Neoplasms; Tegafur; Thymidylate Synthase | 2010 |
Gimeracil, a component of S-1, may enhance the antitumor activity of X-ray irradiation in human cancer xenograft models in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Combined Modality Therapy; Drug Combinations; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Oxonic Acid; Pyridines; Radiation-Sensitizing Agents; Tegafur; Whole-Body Irradiation; Xenograft Model Antitumor Assays | 2010 |
Efficacy of S-1 in patients with capecitabine-resistant breast cancer-Japan Breast Cancer Research Network (JBCRN) 04-1 trial.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Capecitabine; Deoxycytidine; Disease-Free Survival; Drug Combinations; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Middle Aged; Neoplasm Metastasis; Oxonic Acid; Retrospective Studies; Salvage Therapy; Tegafur; Treatment Outcome | 2010 |
Effect of S-1 adjuvant chemotherapy on survival following recurrence and efficacy of first-line treatment in recurrent gastric cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Recurrence; Retrospective Studies; Stomach Neoplasms; Tegafur; Treatment Outcome | 2010 |
Chemosensitivity test for 5-fluorouracil and 5-chloro-2, 4-dihydroxypyridine predicts outcome of gastric cancer patients receiving S-1 postoperatively.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Combinations; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Oxonic Acid; Postoperative Care; Predictive Value of Tests; Pyridines; Stomach Neoplasms; Survival Analysis; Tegafur; Treatment Outcome | 2010 |
Standard-dose tegafur combined with uracil is not safe treatment after severe toxicity from 5-fluorouracil or capecitabine.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Humans; Prodrugs; Rectal Neoplasms; Tegafur | 2010 |
[A case of capecitabine-resistant recurrent breast cancer found to be responsive to S-1].
Topics: Breast Neoplasms; Capecitabine; Deoxycytidine; Drug Combinations; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Tegafur | 2010 |
Combined therapy with a thymidylate synthase-inhibiting vector and S-1 has effective antitumor activity against 5-FU-resistant tumors.
Topics: Adenoviridae; Animals; Antimetabolites, Antineoplastic; Apoptosis; Blotting, Western; Cell Proliferation; Colorectal Neoplasms; Combined Modality Therapy; Drug Combinations; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; Genetic Therapy; Genetic Vectors; Humans; Male; Mice; Mice, Nude; Oxonic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Survival Rate; Tegafur; Thymidylate Synthase; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2011 |
Combined chemoradiotherapy for early glottic cancer in clinical practice in Japan: analysis of 10 institutions.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Female; Fluorouracil; Glottis; Humans; Japan; Laryngeal Neoplasms; Male; Middle Aged; Tegafur; Uracil | 2010 |
[Long-term control of sacral metastasis from rectal cancer with S-1 + radiation treatment (RT) and mFOLFOX6 combination therapy--a case report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Drug Combinations; Fluorouracil; Humans; Leucovorin; Male; Organoplatinum Compounds; Oxonic Acid; Radiotherapy Dosage; Rectal Neoplasms; Sacrum; Tegafur | 2010 |
[A long-term survival case of rectal cancer with Virchow's lymph node metastasis by multimodality therapy].
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Combined Modality Therapy; Fluorouracil; Humans; Irinotecan; Leucovorin; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Organoplatinum Compounds; Rectal Neoplasms; Tegafur; Uracil | 2010 |
[A case of recurrent sigmoid colon cancer with adrenal and para-aortic lymph node metastasis successfully treated by operation and chemotherapy].
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Aorta; Bevacizumab; Camptothecin; Combined Modality Therapy; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Sigmoid Neoplasms; Tegafur; Uracil | 2010 |
[A case of unresectable multiple hepatic metastases from colorectal cancer successfully treated with IRIS (S-1, CPT-11) therapy].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Combinations; Fluorouracil; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Oxonic Acid; Tegafur; Tumor Burden | 2010 |
[A long-term disease-free survival case of advanced rectal cancer with massive metastasis to the lateral pelvic and para-aortic lymph nodes].
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Aorta, Abdominal; Camptothecin; Combined Modality Therapy; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Lymph Node Excision; Lymphatic Metastasis; Male; Oxonic Acid; Pelvis; Rectal Neoplasms; Tegafur; Vitamin B Complex | 2010 |
[A case report of primary adenocarcinoma of small intestine].
Topics: Adenocarcinoma; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; Humans; Ileal Neoplasms; Intestinal Neoplasms; Leucovorin; Lymphatic Metastasis; Middle Aged; Organoplatinum Compounds; Ovarian Neoplasms; Oxonic Acid; Tegafur | 2010 |
Retrospective cohort study on the safety and efficacy of bevacizumab with chemotherapy for metastatic colorectal cancer patients: the HGCSG0801 study.
Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cohort Studies; Colorectal Neoplasms; Confidence Intervals; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Epistaxis; Female; Fluorouracil; Gastrointestinal Hemorrhage; Humans; Hypertension; Irinotecan; Japan; Kaplan-Meier Estimate; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxonic Acid; Proteinuria; Retrospective Studies; Tegafur; Thrombosis; Treatment Outcome | 2011 |
Low-dose docetaxel enhances the sensitivity of S-1 in a xenograft model of human castration resistant prostate cancer.
Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Docetaxel; Drug Combinations; Drug Synergism; Fluorouracil; Humans; Ki-67 Antigen; Male; Mice; Mice, SCID; Oxonic Acid; Prostatectomy; Prostatic Neoplasms; Taxoids; Tegafur; Thymidylate Synthase; Xenograft Model Antitumor Assays | 2012 |
[A case of multiple para-aortic lymph node metastases from squamous cell carcinoma of an unknown primary responding completely to chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta; Carcinoma, Squamous Cell; Cisplatin; Drug Combinations; Fluorouracil; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasms, Unknown Primary; Oxonic Acid; Positron-Emission Tomography; Remission Induction; Tegafur; Tomography, X-Ray Computed | 2011 |
Metronomic S-1 chemotherapy and vandetanib: an efficacious and nontoxic treatment for hepatocellular carcinoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Proliferation; Drug Combinations; ErbB Receptors; Fluorouracil; Humans; Immunoenzyme Techniques; Lung Neoplasms; Male; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Mice, Nude; Oxonic Acid; Piperidines; Quinazolines; Tegafur; Tumor Cells, Cultured | 2011 |
Association analysis of CYP2A6 genotypes and haplotypes with 5-fluorouracil formation from tegafur in human liver microsomes.
Topics: Adolescent; Adult; Alleles; Antimetabolites, Antineoplastic; Aryl Hydrocarbon Hydroxylases; Child; Cytochrome P-450 CYP2A6; Female; Fluorouracil; Genotype; Haplotypes; Humans; Male; Microsomes, Liver; Middle Aged; Polymorphism, Genetic; Tegafur; Young Adult | 2011 |
Sorafenib augments cytotoxic effect of S-1 in vitro and in vivo through TS suppression.
Topics: Animals; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Cell Line, Tumor; Drug Combinations; Drug Synergism; E2F1 Transcription Factor; Female; Fluorouracil; Humans; Kidney Neoplasms; Mice; Mice, Inbred BALB C; Niacinamide; Oxonic Acid; Phenylurea Compounds; Pyridines; RNA, Messenger; Sorafenib; Tegafur; Thymidylate Synthase | 2011 |
Predictive values of 5-fluorouracil pathway genes for S-1 treatment in patients with advanced gastric cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Multivariate Analysis; Oxonic Acid; Polymerase Chain Reaction; Retrospective Studies; RNA, Messenger; Stomach Neoplasms; Survival; Tegafur; Treatment Outcome; Young Adult | 2011 |
Proteomic differential display analysis for TS-1-resistant and -sensitive pancreatic cancer cells using two-dimensional gel electrophoresis and mass spectrometry.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Drug Combinations; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Fluorouracil; Humans; Mass Spectrometry; Neoplasm Proteins; Oxonic Acid; Pancreatic Neoplasms; Proteomics; Pyridines; Tegafur | 2011 |
Stereotactic radiosurgery in combination with chemotherapy as primary treatment for head and neck cancer.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Disease Progression; Drug Combinations; Feasibility Studies; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Magnetic Resonance Imaging; Male; Middle Aged; Multimodal Imaging; Neoplasm Recurrence, Local; Neoplasm Staging; Oxonic Acid; Patient Care Planning; Positron-Emission Tomography; Radiosurgery; Remission Induction; Retrospective Studies; Survival Rate; Tegafur; Tomography, X-Ray Computed; Treatment Outcome | 2012 |
[Assessment of quality of life by questionnaires between S-1/CPT-11 and mFOLFOX6 in patients with advanced colorectal cancer].
Topics: Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Oxonic Acid; Quality of Life; Surveys and Questionnaires; Tegafur | 2011 |
Adjuvant radio-chemotherapy after extended or simple cholecystectomy in gallbladder cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Capecitabine; Chemotherapy, Adjuvant; Cholecystectomy; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Gallbladder Neoplasms; Gemcitabine; Humans; Male; Middle Aged; Radiotherapy, Adjuvant; Survival Rate; Tegafur; Treatment Outcome; Uracil | 2011 |
[Pancreatoduodenectomy for locally advanced ascending colon cancer after neoadjuvant chemotherapy (mFOLFOX6)].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Combinations; Fluorouracil; Humans; Leucovorin; Male; Neoadjuvant Therapy; Organoplatinum Compounds; Oxonic Acid; Pancreaticoduodenectomy; Tegafur; Tomography, X-Ray Computed | 2011 |
Prognostic significance of glucose transporter-1 (GLUT1) gene expression in rectal cancer after preoperative chemoradiotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell Line, Tumor; Chemoradiotherapy; Female; Fluorouracil; Gene Expression; Glucose Transporter Type 1; Humans; Ki-67 Antigen; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm, Residual; Preoperative Care; Prognosis; Rectal Neoplasms; Remission Induction; Retrospective Studies; ROC Curve; Tegafur; Tumor Cells, Cultured | 2012 |
Safety and outcome of chemoradiotherapy in elderly patients with rectal cancer: results from two French tertiary centres.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; France; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Neoplasm Metastasis; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Retrospective Studies; Tegafur; Vitamin B Complex | 2012 |
Antitumor effect of cetuximab in combination with S-1 in EGFR-amplified gastric cancer cells.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cetuximab; Combined Modality Therapy; Drug Combinations; ErbB Receptors; Female; Fluorouracil; Gene Amplification; Humans; Male; Mice; Mice, Nude; Middle Aged; Oxonic Acid; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Stomach Neoplasms; Tegafur; Xenograft Model Antitumor Assays | 2012 |
Reliability of tumor primary cultures as a model for drug response prediction: expression profiles comparison of tissues versus primary cultures from colorectal cancer patients.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cisplatin; Colorectal Neoplasms; Deoxycytidine; Down-Regulation; Doxorubicin; Etoposide; Floxuridine; Fluorescent Antibody Technique; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genomic Instability; Humans; Irinotecan; Metaphase; Paclitaxel; Polymerase Chain Reaction; Predictive Value of Tests; Protein Array Analysis; Reproducibility of Results; Tegafur; Tissue Array Analysis; Tumor Cells, Cultured; Up-Regulation; Uracil | 2012 |
[Development of oral drugs in the standard therapy for metastatic colorectal cancer patients].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Drug Therapy, Combination; Fluorouracil; Humans; Irinotecan; Neoplasm Metastasis; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Tegafur | 2011 |
Fluoropyrimidine plus cisplatin for patients with advanced or recurrent gastric cancer with peritoneal metastasis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascites; Capecitabine; Cisplatin; Deoxycytidine; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Peritoneal Neoplasms; Retrospective Studies; Stomach Neoplasms; Survival Rate; Tegafur; Time Factors; Treatment Outcome | 2013 |
A retrospective comparison of S-1 plus cisplatin and capecitabine plus cisplatin for patients with advanced or recurrent gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cisplatin; Deoxycytidine; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Oxonic Acid; Retrospective Studies; Stomach Neoplasms; Tegafur | 2013 |
Development and utilization of a combined LC-UV and LC-MS/MS method for the simultaneous analysis of tegafur and 5-fluorouracil in human plasma to support a phase I clinical study of oral UFT®/leucovorin.
Topics: Adenocarcinoma; Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chromatography, Liquid; Clinical Trials, Phase I as Topic; Esophageal Neoplasms; Fluorouracil; Humans; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tegafur | 2012 |
[A case of remnant liver metastases after resection of liver metastases from rectal cancer following treatment with 5-FU, L-OHP and CPT-11, with markedly effective treatment by cetuximab plus S-1].
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Combined Modality Therapy; Drug Combinations; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Male; Mutation; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Rectal Neoplasms; Recurrence; Salvage Therapy; Tegafur; Tomography, X-Ray Computed | 2012 |
Serum insulin-like growth factor-1 levels predict outcomes of patients with advanced hepatocellular carcinoma receiving antiangiogenic therapy.
Topics: Administration, Metronomic; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Carcinoma, Hepatocellular; Clinical Trials as Topic; Deoxycytidine; Fluorouracil; Humans; Insulin-Like Growth Factor I; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Prognosis; Serum; Sorafenib; Tegafur; Treatment Outcome | 2012 |
Efficacy of combination chemotherapy using oral fluoropyrimidine S-1 with oxaliplatin (SOX) against colorectal cancer in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Administration Schedule; Drug Combinations; Drug Resistance, Neoplasm; Fluorouracil; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Tegafur; Xenograft Model Antitumor Assays | 2012 |
Multi-institutional analysis of early glottic cancer from 2000 to 2005.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Docetaxel; Female; Fluorouracil; Follow-Up Studies; Glottis; Humans; Laryngeal Neoplasms; Male; Middle Aged; Neoplasm Staging; Prognosis; Survival Rate; Taxoids; Tegafur; Time Factors; Uracil | 2012 |
Early prediction of histopathological response of rectal tumors after one week of preoperative radiochemotherapy using 18 F-FDG PET-CT imaging. A prospective clinical study.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorodeoxyglucose F18; Fluorouracil; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Multimodal Imaging; Neoplasm Staging; Positron-Emission Tomography; Preoperative Care; Prognosis; Prospective Studies; Radiopharmaceuticals; Radiotherapy Dosage; Rectal Neoplasms; Tegafur; Tomography, X-Ray Computed; Uracil | 2012 |
S-1 in colorectal cancer: a new standard of care?
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Humans; Male; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Tegafur | 2012 |
[A case of recurrent gastric cancer showing partial response to capecitabine/CDDP after treatment with S-1/CDDP].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cisplatin; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Male; Oxonic Acid; Recurrence; Salvage Therapy; Stomach Neoplasms; Tegafur | 2012 |
[Predicting drug efficacy-fluorinated pyrimidines (fluorouracil, S-1 and capecitabine)].
Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Neoplasms; Oxonic Acid; Prognosis; Tegafur | 2012 |
An immunoassay method for the pharmacokinetics of 5-fluorouracil in patients with gastric cancer administered adjuvant chemotherapy.
Topics: Aged; Antineoplastic Agents; Area Under Curve; Chemotherapy, Adjuvant; Drug Combinations; Female; Fluorouracil; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Male; Oxonic Acid; Stomach Neoplasms; Tegafur | 2012 |
Upregulation of ERCC1 and DPD expressions after oxaliplatin-based first-line chemotherapy for metastatic colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); DNA Topoisomerases, Type I; DNA-Binding Proteins; Drug Combinations; Endonucleases; Female; Fluorouracil; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Leucovorin; Male; Middle Aged; National Cancer Institute (U.S.); Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Real-Time Polymerase Chain Reaction; Retrospective Studies; RNA, Messenger; Tegafur; United States; Up-Regulation | 2012 |
[Prevention of severe toxicity from capecitabine, 5-fluorouracil and tegafur by screening for DPD-deficiency].
Topics: Aged; Antineoplastic Agents; Capecitabine; Deoxycytidine; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Dose-Response Relationship, Drug; Female; Fluorouracil; Genetic Testing; Genotype; Humans; Male; Middle Aged; Neoplasms; Risk Assessment; Tegafur | 2012 |
Evaluation of 5-FU plasma concentration by 13C breath test in patients treated with oral 5-FU analogs.
Topics: Acetates; Administration, Oral; Aged; Antimetabolites, Antineoplastic; Breath Tests; Carbon Isotopes; Drug Combinations; Esophageal Neoplasms; Female; Fluorouracil; Humans; Intestinal Absorption; Male; Oxonic Acid; Stomach Neoplasms; Tegafur | 2012 |
Salvage chemoradiotherapy after primary chemotherapy for locally advanced pancreatic cancer: a single-institution retrospective analysis.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chemoradiotherapy; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Gemcitabine; Humans; Induction Chemotherapy; Kaplan-Meier Estimate; Male; Middle Aged; Oxonic Acid; Pancreatic Neoplasms; Prognosis; Proportional Hazards Models; Retrospective Studies; Salvage Therapy; Tegafur; Treatment Outcome | 2012 |
[Pharmacokinetics of S-1 capsule in patients with advanced gastric cancer].
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capsules; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Pyridines; Stomach Neoplasms; Tegafur; Uracil | 2012 |
REG Iα is a biomarker for predicting response to chemotherapy with S-1 plus cisplatin in patients with unresectable stage IV gastric cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Combinations; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Lithostathine; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Stomach Neoplasms; Tegafur; Treatment Outcome | 2013 |
Retrospective study as first-line chemotherapy combined anti-VEGF antibody with fluoropyrimidine for frail patients with unresectable or metastatic colorectal cancer.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Drug Combinations; Female; Fluorouracil; Frail Elderly; Humans; Leucovorin; Male; Neoplasm Metastasis; Oxonic Acid; Retrospective Studies; Tegafur; Treatment Failure; Vascular Endothelial Growth Factor A | 2013 |
[Oral chemotherapy for advanced breast cancer].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Humans; Molecular Targeted Therapy; Oxonic Acid; Tegafur | 2012 |
The prognostic nutritional index predicts long-term outcomes of gastric cancer patients independent of tumor stage.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Chemotherapy, Adjuvant; Cisplatin; Deoxycytidine; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Lymphatic Metastasis; Lymphocyte Count; Male; Middle Aged; Nutritional Status; Oxonic Acid; Predictive Value of Tests; Retrospective Studies; Serum Albumin; Stomach Neoplasms; Tegafur; Time Factors; Uracil; Young Adult | 2013 |
Salvage radiation therapy and chemoradiation therapy for postoperative locoregional recurrence of esophageal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinosarcoma; Chemoradiotherapy; Cisplatin; Cohort Studies; Drug Combinations; Esophageal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxonic Acid; Pyridines; Radiotherapy; Retrospective Studies; Salvage Therapy; Survival Rate; Tegafur; Treatment Outcome | 2014 |
New advances in the treatment of gastric cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Cisplatin; Deoxycytidine; Docetaxel; Doxorubicin; Drug Combinations; Etoposide; Fluorouracil; Humans; Leucovorin; Levoleucovorin; Methotrexate; Organoplatinum Compounds; Oxonic Acid; Stomach Neoplasms; Taxoids; Tegafur | 2004 |
Genetic polymorphisms of enzymes related to oral tegafur/uracil therapeutic efficacy in patients with hepatocellular carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aryl Hydrocarbon Hydroxylases; Asian People; Carcinoma, Hepatocellular; Cytochrome P-450 CYP2A6; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Genotype; Hepatitis C; Humans; Japan; Liver Neoplasms; Male; Minisatellite Repeats; Polymorphism, Genetic; Tegafur; Thymidylate Synthase; Uracil | 2013 |
Chemotherapy and resection for gastric cancer with synchronous liver metastases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Drug Combinations; Female; Fluorouracil; Glycosylation; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Oxonic Acid; Pilot Projects; Stomach Neoplasms; Taxoids; Tegafur; Treatment Outcome | 2013 |
Clinical comparison between paclitaxel liposome (Lipusu®) and paclitaxel for treatment of patients with metastatic gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluorouracil; Follow-Up Studies; Humans; Liposomes; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Prognosis; Retrospective Studies; Stomach Neoplasms; Tegafur | 2013 |
Impact of age on the efficacy of newer adjuvant therapies in patients with stage II/III colon cancer: findings from the ACCENT database.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Colectomy; Colorectal Neoplasms; Databases, Factual; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Organoplatinum Compounds; Prognosis; Pyridines; Randomized Controlled Trials as Topic; Risk Assessment; Survival Analysis; Tegafur; Treatment Outcome | 2013 |
Tegafur + gimeracil + oteracil. Just another fluorouracil precursor.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Oxonic Acid; Pyridines; Randomized Controlled Trials as Topic; Stomach Neoplasms; Tegafur | 2013 |
[A case of mediastinal lymph node gastric cancer recurrence during S-1 adjuvant therapy successfully treated with cisplatin + capecitabine as second-line chemotherapy].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Cisplatin; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Lymphatic Metastasis; Male; Oxonic Acid; Stomach Neoplasms; Tegafur | 2013 |
[Approximately four years of survival benefits for a case of gastric cancer postoperative carcinomatous peritonitis by combined modality therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Combined Modality Therapy; Drug Combinations; Fatal Outcome; Female; Fluorouracil; Gastrectomy; Humans; Irinotecan; Methotrexate; Middle Aged; Oxonic Acid; Paclitaxel; Peritoneal Neoplasms; Peritonitis; Stomach Neoplasms; Tegafur; Time Factors | 2013 |
[A case of metastatic colon cancer effectively treated by XELOX and IRIS].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Colonic Neoplasms; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Oxaloacetates; Oxonic Acid; Tegafur; Tomography, X-Ray Computed | 2013 |
Treatment outcome of high-dose-rate interstitial radiation therapy for patients with stage I and II mobile tongue cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brachytherapy; Carboplatin; Chemoradiotherapy; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Infusions, Intravenous; Injections, Intra-Arterial; Kaplan-Meier Estimate; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Pyridines; Radiotherapy Dosage; Retrospective Studies; Tegafur; Tongue Neoplasms; Treatment Outcome | 2013 |
Clinical Pharmacogenetics Implementation Consortium guidelines for dihydropyrimidine dehydrogenase genotype and fluoropyrimidine dosing.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Genotype; Humans; Incidental Findings; Male; Risk Assessment; Sex Factors; Tegafur | 2013 |
Long-term outcomes and prognostic factors of patients with advanced gastric cancer treated with S-1 plus cisplatin combination chemotherapy as a first-line treatment.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Prognosis; Stomach Neoplasms; Tegafur; Treatment Outcome | 2014 |
Feasibility study of oxaliplatin with oral S-1 or capecitabine as first-line therapy for patients with metastases from colorectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Disease-Free Survival; Drug Combinations; Feasibility Studies; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Peritoneal Neoplasms; Tegafur | 2013 |
C-reactive protein as predictor of recurrence in patients with rectal cancer undergoing chemoradiotherapy followed by surgery.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; C-Reactive Protein; Carcinoembryonic Antigen; Carcinoma, Signet Ring Cell; Chemoradiotherapy; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphocytes; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Neutrophils; Prognosis; Rectal Neoplasms; Survival Rate; Tegafur; Uracil | 2013 |
Economic evaluation of first-line adjuvant chemotherapies for resectable gastric cancer patients in China.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Capecitabine; Chemotherapy, Adjuvant; China; Clinical Trials, Phase III as Topic; Cost-Benefit Analysis; Deoxycytidine; Disease Progression; Disease-Free Survival; Drug Combinations; Fluorouracil; Gastrectomy; Humans; Markov Chains; Middle Aged; Models, Statistical; Oxaloacetates; Oxonic Acid; Probability; Quality-Adjusted Life Years; Stomach Neoplasms; Tegafur | 2013 |
[A case of hepatocellular carcinoma (Vp4)-combination therapy prolonged survival in a patient with advanced hepatocellular carcinoma with a tumor thrombus in the portal vein trunk].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Combined Modality Therapy; Fluorouracil; Hepatectomy; Humans; Liver Neoplasms; Male; Portal Vein; Tegafur; Thrombosis; Time Factors; Treatment Outcome | 2013 |
Usefulness of monthly chemotherapy for patients with unresectable metastatic colorectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Follow-Up Studies; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Peritoneal Neoplasms; Prognosis; Survival Rate; Tegafur | 2014 |
Twenty-six cases of advanced ampullary adenocarcinoma treated with systemic chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Ampulla of Vater; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Common Bile Duct Neoplasms; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Male; Medical Records; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Oxonic Acid; Prognosis; Pyridines; Retrospective Studies; Tegafur; Treatment Outcome | 2014 |
A systemic analysis of S-1 regimens for treatment of patients with colon cancer.
Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Fluorouracil; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Tegafur; Treatment Outcome | 2014 |
Metronomic adjuvant chemotherapy improves treatment outcome in nasopharyngeal carcinoma patients with postradiation persistently detectable plasma Epstein-Barr virus deoxyribonucleic acid.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chemotherapy, Adjuvant; Cisplatin; DNA, Viral; Drug Combinations; Epirubicin; Female; Fluorouracil; Herpesvirus 4, Human; Humans; Induction Chemotherapy; Leucovorin; Male; Middle Aged; Mitomycin; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Radiotherapy, Conformal; Retrospective Studies; Tegafur; Treatment Outcome; Uracil | 2014 |
[A case of Stage IV sigmoid colon cancer that achieved long-term survival with oral anticancer drugs].
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Neoplasm Staging; Oxonic Acid; Sigmoid Neoplasms; Tegafur; Time Factors | 2014 |
[A retrospective study of tegafur/uracil compared with cyclophosphamide, methotrexate, and fluorouracil as adjuvant chemotherapy in patients with node-negative, triple-negative breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cyclophosphamide; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Recurrence; Retrospective Studies; Tegafur; Triple Negative Breast Neoplasms; Uracil | 2014 |
Prognostic Significance of Nodal Ratio in Patients Undergoing Adjuvant Chemoradiotherapy After Curative Resection for Ampullary Cancer.
Topics: Adult; Aged; Ampulla of Vater; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Common Bile Duct Neoplasms; Disease-Free Survival; Dose Fractionation, Radiation; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Mitomycin; Neoplasm Recurrence, Local; Pancreaticoduodenectomy; Retrospective Studies; Survival Rate; Tegafur; Treatment Failure | 2016 |
Inferior oncological prognosis of surgery without oral chemotherapy for stage III colon cancer in clinical settings.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Rate; Tegafur; Uracil; Young Adult | 2014 |
[A case of S-1/CDDP-resistant recurrent gastric cancer responsive to capecitabine/CDDP].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cisplatin; Combined Modality Therapy; Deoxycytidine; Drug Combinations; Drug Resistance, Neoplasm; Fluorouracil; Humans; Liver Neoplasms; Male; Neoplasm Staging; Oxonic Acid; Stomach Neoplasms; Tegafur | 2014 |
[A case of advanced rectal cancer that showed complete response to the addition of XELOX+bevacizumab therapy to preoperative chemoradiotherapy with S-1/CPT-11].
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Chemoradiotherapy; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Neoplasm Staging; Oxaloacetates; Oxonic Acid; Rectal Neoplasms; Tegafur | 2014 |
Post-chemoradiation intraoperative electron-beam radiation therapy boost in resected locally advanced rectal cancer: long-term results focused on topographic pattern of locoregional relapse.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Electrons; Female; Fluorouracil; Humans; Intraoperative Care; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Organoplatinum Compounds; Prognosis; Radiotherapy, Conformal; Rectal Neoplasms; Tegafur | 2014 |
Effect of CYP2A6 genetic polymorphism on the metabolic conversion of tegafur to 5-fluorouracil and its enantioselectivity.
Topics: Cell Line; Coumarins; Cytochrome P-450 CYP2A6; DNA, Complementary; Escherichia coli; Fluorouracil; Humans; Microsomes, Liver; Nicotine; Polymorphism, Genetic; Sf9 Cells; Tegafur | 2014 |
Outcomes in elderly patients treated with a single-agent or combination regimen as first-line chemotherapy for recurrent or metastatic gastric cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Drug Combinations; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Organoplatinum Compounds; Oxonic Acid; Palliative Care; Prognosis; Retrospective Studies; Stomach Neoplasms; Tegafur; Treatment Outcome | 2015 |
Species variation in the enantioselective metabolism of tegafur to 5-fluorouracil among rats, dogs and monkeys.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Biological Availability; Cytochrome P-450 Enzyme System; Dogs; Fluorouracil; Injections, Intravenous; Macaca fascicularis; Male; Metabolic Clearance Rate; Microsomes, Liver; Prodrugs; Rats, Sprague-Dawley; Species Specificity; Stereoisomerism; Tegafur | 2014 |
Evaluation of 5-fluorouracil metabolic enzymes as predictors of response to adjuvant chemotherapy outcomes in patients with stage II/III colorectal cancer: a decision-curve analysis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chemotherapy, Adjuvant; Colorectal Neoplasms; Decision Support Techniques; Dihydrouracil Dehydrogenase (NADP); Disease-Free Survival; Female; Fluorouracil; Gene Expression; Humans; Leucovorin; Male; Middle Aged; Neoplasm Recurrence, Local; Orotate Phosphoribosyltransferase; Predictive Value of Tests; RNA, Messenger; Tegafur; Thymidine Phosphorylase; Thymidylate Synthase | 2014 |
S-1-Based versus capecitabine-based preoperative chemoradiotherapy in the treatment of locally advanced rectal cancer: a matched-pair analysis.
Topics: Capecitabine; Chemoradiotherapy; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Humans; Male; Matched-Pair Analysis; Middle Aged; Neoplasm Staging; Oxonic Acid; Postoperative Care; Preoperative Care; Rectal Neoplasms; Tegafur; Treatment Outcome | 2014 |
Adaptation of international guidelines for metastatic colorectal cancer: an asian consensus.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Asia; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Colonic Neoplasms; Combined Modality Therapy; Deoxycytidine; Drug Combinations; ErbB Receptors; Fluorouracil; Guideline Adherence; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Magnetic Resonance Imaging; Metastasectomy; Neoplasm Staging; Organoplatinum Compounds; Oxaloacetates; Oxonic Acid; Panitumumab; Practice Guidelines as Topic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Rectal Neoplasms; Tegafur; Tomography, X-Ray Computed | 2014 |
[A case of gastric cancer with peritoneal dissemination successfully treated with low-dose S-1 or capecitabine chemotherapy for five years].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Drug Combinations; Fatal Outcome; Fluorouracil; Humans; Male; Oxonic Acid; Peritoneal Neoplasms; Stomach Neoplasms; Tegafur; Time Factors | 2014 |
Adjuvant chemoradiation with 5-fluorouracil/leucovorin versus S-1 in gastric cancer patients following D2 lymph node dissection surgery: a feasibility study.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ring Cell; Chemoradiotherapy, Adjuvant; Combined Modality Therapy; Drug Combinations; Feasibility Studies; Female; Fluorouracil; Follow-Up Studies; Gastrectomy; Humans; Leucovorin; Lymph Node Excision; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Oxonic Acid; Prognosis; Retrospective Studies; Stomach Neoplasms; Survival Rate; Tegafur | 2014 |
Cost-effectiveness analysis of adjuvant chemotherapies in patients presenting with gastric cancer after D2 gastrectomy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; China; Clinical Trials as Topic; Cost-Benefit Analysis; Deoxycytidine; Disease-Free Survival; Drug Combinations; Fluorouracil; Gastrectomy; Humans; Markov Chains; Models, Economic; Oxaloacetates; Oxonic Acid; Quality-Adjusted Life Years; Stomach Neoplasms; Survival Rate; Tegafur | 2014 |
Surgical outcomes in patients with locally advanced gastric cancer treated with S-1 and oxaliplatin as neoadjuvant chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; Follow-Up Studies; Gastrectomy; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Postoperative Complications; Prognosis; Prospective Studies; Remission Induction; Retrospective Studies; Stomach Neoplasms; Survival Rate; Tegafur; Young Adult | 2015 |
Gastrointestinal toxicities of 5-fluorouracil increase the proportion of regulatory T cells in intestinal tract: advantages of alternate-day S-1 administration.
Topics: Animals; Antimetabolites, Antineoplastic; Disease Models, Animal; Drug Combinations; Fluorouracil; Gastrointestinal Diseases; Gastrointestinal Tract; Male; Mice; Mice, Inbred BALB C; Oxonic Acid; T-Lymphocytes, Regulatory; Tegafur | 2015 |
Multicenter observational cohort study of post-operative treatment for completely resected non-small-cell lung cancer of pathological Stage I (T1 >2 cm and T2 in TNM classification version 6).
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Cohort Studies; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Oxonic Acid; Patient Selection; Postoperative Period; Prodrugs; Proportional Hazards Models; Tegafur; Uracil | 2015 |
[A case of gastric cancer showing response to first-line XP regimen after lymph node recurrence during the administration of S-1 as postoperative adjuvant chemotherapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Cisplatin; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Humans; Lymphatic Metastasis; Oxonic Acid; Recurrence; Salvage Therapy; Stomach Neoplasms; Tegafur | 2014 |
Long-Term Survival of Patient with Epstein-Barr Virus-Positive Gastric Cancer Treated with Chemotherapy: Case Report.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Epstein-Barr Virus Infections; Female; Fluorouracil; Follow-Up Studies; Herpesvirus 4, Human; Humans; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Paclitaxel; Prognosis; Stomach Neoplasms; Survival Rate; Tegafur; Time Factors | 2016 |
Modified FOLFIRINOX for Locally Advanced and Metastatic Pancreatic Cancer Patients Resistant to Gemcitabine and S-1 in Japan: A Single Institutional Experience.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Deoxycytidine; Disease Progression; Disease-Free Survival; Drug Combinations; Drug Resistance, Neoplasm; Female; Fluorouracil; Gemcitabine; Humans; Irinotecan; Japan; Kaplan-Meier Estimate; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Pancreatic Neoplasms; Tegafur; Time Factors; Treatment Outcome | 2014 |
Lethal leukoencephalopathy secondary to Tegafur, a 5-fluorouracil prodrug.
Topics: Aged; Antimetabolites, Antineoplastic; Fatal Outcome; Fluorouracil; Humans; Leukoencephalopathies; Male; Prodrugs; Tegafur | 2015 |
Development of an S-1 dosage formula based on renal function by a prospective pharmacokinetic study.
Topics: Aged; Antimetabolites, Antineoplastic; Drug Combinations; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Prognosis; Prospective Studies; Renal Insufficiency; Stomach Neoplasms; Tegafur; Tissue Distribution | 2016 |
Hepatic arterial infusion chemotherapy using fluorouracil, epirubicin, and mitomycin C for patients with liver metastases from gastric cancer after treatment failure of systemic S-1 plus cisplatin.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Catheters, Indwelling; Cisplatin; Disease Progression; Drug Combinations; Epirubicin; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitomycin; Oxonic Acid; Stomach Neoplasms; Survival Rate; Tegafur; Tomography, X-Ray Computed; Treatment Failure; Treatment Outcome | 2016 |
Stage III Colon Cancer: The Individualized Strategy of Adjuvant Chemotherapy for Aged Under and Over 70.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Precision Medicine; Prognosis; Retrospective Studies; Tegafur | 2015 |
Tegafur Substitution for 5-Fu in Combination with Actinomycin D to Treat Gestational Trophoblastic Neoplasm.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Female; Fluorouracil; Gestational Trophoblastic Disease; Humans; Pregnancy; Tegafur | 2015 |
[The progress of chemotherapy for advanced pancreatic cancer].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Drug Combinations; Erlotinib Hydrochloride; Fluorouracil; Gemcitabine; Humans; Leucovorin; Organoplatinum Compounds; Oxonic Acid; Pancreatic Neoplasms; Tegafur | 2015 |
Efficacy and feasibility of ambulatory treatment-based monthly nedaplatin plus S-1 in definitive or salvage concurrent chemoradiotherapy for early, advanced, and relapsed esophageal cancer.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Drug Administration Schedule; Drug Combinations; Esophageal Neoplasms; Female; Fluorouracil; Hospitalization; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Organoplatinum Compounds; Oxonic Acid; Retrospective Studies; Salvage Therapy; Tegafur | 2016 |
Induction docetaxel and S-1 followed by concomitant radiotherapy with low-dose daily cisplatin in locally advanced head and neck carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Docetaxel; Drug Combinations; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Induction Chemotherapy; Male; Middle Aged; Oxonic Acid; Taxoids; Tegafur; Young Adult | 2016 |
[Adjuvant Systemic Chemotherapy with S-1/Oxaliplatin or mFOLFOX6 after Curative Resection of Distant Metastases in Patients with Colorectal Cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Rectal Neoplasms; Recurrence; Retrospective Studies; Tegafur | 2016 |
Clinical management of squamous cell carcinoma associated with sinonasal inverted papilloma.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemoradiotherapy, Adjuvant; Disease-Free Survival; Drug Combinations; Epistaxis; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Maxillary Sinus Neoplasms; Middle Aged; Nasal Cavity; Nasal Obstruction; Neoplasm Staging; Neoplasms, Multiple Primary; Nose Neoplasms; Otorhinolaryngologic Surgical Procedures; Oxonic Acid; Papilloma, Inverted; Paranasal Sinus Neoplasms; Radiotherapy, Adjuvant; Retrospective Studies; Squamous Cell Carcinoma of Head and Neck; Tegafur; Tomography, X-Ray Computed | 2017 |
Paradoxical Reductions in Serum Anti-p53 Autoantibody Levels by Chemotherapy in Unresectable Colorectal Cancer: An Observational Study.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Bevacizumab; Camptothecin; Capecitabine; Carcinoembryonic Antigen; Cetuximab; Colorectal Neoplasms; Disease Progression; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Middle Aged; Organoplatinum Compounds; Oxonic Acid; Palliative Care; Pregnancy; Survival Rate; Tegafur; Tumor Suppressor Protein p53 | 2016 |
Cytomegalovirus colitis in a patient undergoing postoperative adjuvant chemotherapy for lung adenocarcinoma with uracil-tegafur.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colitis; Cytomegalovirus; Cytomegalovirus Infections; Female; Fluorouracil; Humans; Lung Neoplasms; Postoperative Care; Tegafur | 2016 |
Adult T-cell leukemia/lymphoma in patients with head and neck cancer after S-1 chemotherapy.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Combinations; Female; Fluorouracil; Head and Neck Neoplasms; Human T-lymphotropic virus 1; Humans; Leukemia-Lymphoma, Adult T-Cell; Male; Middle Aged; Neoplasms, Second Primary; Otorhinolaryngologic Surgical Procedures; Oxonic Acid; Radiotherapy; Squamous Cell Carcinoma of Head and Neck; Taxoids; Tegafur | 2017 |
Usefulness of chemoradiotherapy for inoperable gastric cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cisplatin; Drug Combinations; Female; Fluorouracil; Humans; Japan; Male; Neoplasm Recurrence, Local; Oxonic Acid; Radiotherapy, Conformal; Retrospective Studies; Stomach Neoplasms; Survival Rate; Tegafur | 2017 |
Paclitaxel/oxaliplatin/fluorouracil (TOF) regimen versus S-1/oxaliplatin (SOX) regimen for metastatic gastric cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Paclitaxel; Stomach Neoplasms; Survival Analysis; Tegafur; Tomography, X-Ray Computed; Treatment Outcome; Young Adult | 2017 |
Platinum-based Doublet Chemotherapy for Advanced Gastric Cancer with Disseminated Intravascular Coagulation.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disseminated Intravascular Coagulation; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Oxonic Acid; Paclitaxel; Stomach Neoplasms; Tegafur; Treatment Outcome | 2017 |
Short-term efficacy of different chemotherapy regimens in the treatment of advanced gastric cancer: a network meta-analysis.
Topics: Capecitabine; Drug Combinations; Fluorouracil; Humans; Network Meta-Analysis; Oxonic Acid; Stomach Neoplasms; Tegafur | 2017 |
Timing of initiation of adjuvant chemotherapy for gastric cancer: A case-matched comparison study of laparoscopic vs. open surgery.
Topics: Abdominal Abscess; Adult; Aged; Aged, 80 and over; Anastomotic Leak; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Case-Control Studies; Chemotherapy, Adjuvant; Cisplatin; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Laparoscopy; Laparotomy; Lymph Node Excision; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Oxonic Acid; Pancreatic Fistula; Postoperative Complications; Retrospective Studies; Stomach Neoplasms; Tegafur; Time Factors; Time-to-Treatment | 2017 |
Prediction of Pathological Complete Response Using Endoscopic Findings and Outcomes of Patients Who Underwent Watchful Waiting After Chemoradiotherapy for Rectal Cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Chemoradiotherapy; Colonoscopy; Digestive System Surgical Procedures; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Leucovorin; Logistic Models; Lymph Node Excision; Male; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Neoplasm Staging; Odds Ratio; Pyridines; Rectal Neoplasms; Rectum; Remission Induction; Retrospective Studies; Tegafur; Treatment Outcome; Watchful Waiting | 2017 |
Comparison of five tumor regression grading systems for gastric adenocarcinoma after neoadjuvant chemotherapy: a retrospective study of 192 cases from National Cancer Center in China.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; China; Cisplatin; Disease-Free Survival; Docetaxel; Drug Combinations; Esophagogastric Junction; Female; Fluorouracil; Gastrectomy; Humans; Male; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Prognosis; Proportional Hazards Models; Pyridines; Remission Induction; Retrospective Studies; Stomach Neoplasms; Survival Analysis; Taxoids; Tegafur; Treatment Outcome; Tumor Burden | 2017 |
Oral tegafur-uracil as metronomic therapy following intravenous FOLFOX for stage III colon cancer.
Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Retrospective Studies; Survival Rate; Tegafur; Uracil | 2017 |
Tegafur/gimeracil/oteracil (TS-1)-induced erythroderma with an extensive mucosal involvement and hand-foot syndrome.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dermatitis, Exfoliative; Drug Combinations; Drug Eruptions; Fluorouracil; Hand-Foot Syndrome; Humans; Leucovorin; Liver Neoplasms; Male; Organoplatinum Compounds; Oxonic Acid; Pyridines; Tegafur | 2017 |
Gene expression levels of gamma-glutamyl hydrolase in tumor tissues may be a useful biomarker for the proper use of S-1 and tegafur-uracil/leucovorin in preoperative chemoradiotherapy for patients with rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chemoradiotherapy; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; gamma-Glutamyl Hydrolase; Gene Expression Regulation, Neoplastic; Humans; Leucovorin; Male; Middle Aged; Oxonic Acid; Rectal Neoplasms; Reproducibility of Results; Tegafur; Treatment Outcome | 2017 |
Safe administration of S-1 after 5-fluorouracil-induced cardiotoxicity in a patient with colorectal cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cardiotoxicity; Colorectal Neoplasms; Drug Combinations; Fluorouracil; Humans; Male; Oxonic Acid; Pyridines; Tegafur | 2017 |
[A Case of Effective Chemoradiotherapy Using mFOLFOX6 for Locally Advanced Rectal Cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradiotherapy; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Oxonic Acid; Rectal Neoplasms; Tegafur; Treatment Outcome | 2017 |
A high throughput immunoassay for the therapeutic drug monitoring of tegafur.
Topics: Antineoplastic Agents; Drug Monitoring; Enzyme-Linked Immunosorbent Assay; Fluorouracil; Humans; Tegafur | 2017 |
Suggestion of added value by bevacizumab to chemotherapy in patients with unresectable or recurrent small bowel cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Cisplatin; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Intestinal Neoplasms; Intestine, Small; Japan; Leucovorin; Male; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxonic Acid; Retrospective Studies; Survival Rate; Tegafur | 2017 |
TS-1 (tegafur/gimeracil/oteracil)-induced systemic lupus erythematosus with skin lesions and anti-Sm antibody.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Drug Therapy, Combination; Fluorouracil; Gemcitabine; Humans; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Male; Oxonic Acid; Pancreatic Neoplasms; Pyridines; Renal Insufficiency; Tegafur | 2017 |
Effect of Sipjeondaebo-Tang on the Pharmacokinetics of S-1, an Anticancer Agent, in Rats Evaluated by Population Pharmacokinetic Modeling.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Drug Combinations; Drugs, Chinese Herbal; Fluorouracil; Herb-Drug Interactions; Humans; Male; Models, Biological; Oxonic Acid; Pyridines; Rats, Sprague-Dawley; Tegafur | 2017 |
Adoptive immunotherapy combined with FP treatment for head and neck cancer: An in vitro study.
Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Cisplatin; Combined Modality Therapy; Cytomegalovirus; Drug Resistance, Neoplasm; Fluorouracil; Head and Neck Neoplasms; Humans; Immunotherapy, Adoptive; Interferon-gamma; Myeloid-Derived Suppressor Cells; Neoplasm Staging; Phosphoproteins; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Regulatory; Tegafur; Tumor Microenvironment; Uracil; Viral Matrix Proteins | 2017 |
Complete response of metastatic gastric cancer to chemoimmunotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Female; Fluorouracil; Humans; Middle Aged; Neoplasm Metastasis; Oxonic Acid; Paclitaxel; Remission Induction; Stomach Neoplasms; Tegafur | 2017 |
The Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio Are Prognostic Factors in Patients with Locally Advanced Pancreatic Cancer Treated with Chemoradiotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Capecitabine; Chemoradiotherapy; Cisplatin; Deoxycytidine; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Gemcitabine; Humans; Lymphocyte Count; Lymphocytes; Male; Middle Aged; Neutrophils; Pancreatic Neoplasms; Platelet Count; Prognosis; Retrospective Studies; Tegafur; Tumor Burden; Uracil | 2018 |
Efficacy of Adjuvant S-1 Versus XELOX Chemotherapy for Patients with Gastric Cancer After D2 Lymph Node Dissection: A Retrospective, Multi-Center Observational Study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Lymph Node Excision; Male; Middle Aged; Neoplasm Staging; Oxaloacetates; Oxonic Acid; Retrospective Studies; Stomach Neoplasms; Tegafur | 2018 |
Pre-exposure to Fluorouracil Increased Trifluridine Incorporation and Enhanced its Anti-tumor Effect for Colorectal Cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; DNA, Neoplasm; Drug Combinations; Fluorouracil; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Oxonic Acid; Prognosis; Tegafur; Trifluridine; Xenograft Model Antitumor Assays | 2018 |
Adjuvant Chemotherapy Versus Chemoradiotherapy Versus Surgery Alone for Early Gastric Cancer with One or Two Lymph Node Metastasis.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Cisplatin; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Gastrectomy; Humans; Leucovorin; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Oxaliplatin; Oxaloacetates; Oxonic Acid; Pyridines; Radiotherapy Dosage; Stomach Neoplasms; Tegafur | 2018 |
The efficacy of combination of induction chemotherapy and irreversible electroporation ablation for patients with locally advanced pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Catheter Ablation; Chemotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Drug Combinations; Electrochemotherapy; Fluorouracil; Gemcitabine; Humans; Induction Chemotherapy; Laparotomy; Oxonic Acid; Pancreatic Neoplasms; Pyridines; Survival Rate; Tegafur | 2018 |
Determination of 5-fluorouracil and tegafur in tear fluid of patients treated with oral fluoropyrimidine anticancer agent, S-1.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Drug Combinations; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunosuppressive Agents; Male; Middle Aged; Neoplasms; Oxonic Acid; Tears; Tegafur | 2018 |
[Efficacy of S-1 in Advanced Non-small Cell Lung Cancer Patients Treated
with More Than Two Lines of Chemotherapy].
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Combinations; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Middle Aged; Oxonic Acid; Retrospective Studies; Safety; Survival Analysis; Tegafur; Treatment Outcome | 2018 |
Efficacy after preoperative capecitabine and oxaliplatin (XELOX) versus docetaxel, oxaliplatin and S1 (DOS) in patients with locally advanced gastric adenocarcinoma: a propensity score matching analysis.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Docetaxel; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Oxaliplatin; Oxaloacetates; Oxonic Acid; Propensity Score; Retrospective Studies; Stomach Neoplasms; Tegafur | 2018 |
Identification of Predictors of Recurrence in Patients with Lower Rectal Cancer Undergoing Neoadjuvant Chemotherapy: A Direct Comparison of Short-Course and Long-Course Chemoradiotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Rectal Neoplasms; Retrospective Studies; Survival Rate; Tegafur; Uracil | 2019 |
Clinical efficacy and safety of S-1 monotherapy in the treatment of advanced breast cancer in elderly patients.
Topics: Aged; Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Drug Combinations; Female; Fluorouracil; Humans; Middle Aged; Oxonic Acid; Quality of Life; Tegafur; Treatment Outcome | 2018 |
Cost minimization comparison of oral UFT/leucovorin versus 5-fluorouracil/leucovorin as adjuvant therapy for colorectal cancer in Taiwan.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Combined Modality Therapy; Cost Control; Female; Fluorouracil; Health Care Costs; Humans; Leucovorin; Male; Middle Aged; Taiwan; Tegafur; Treatment Outcome; Uracil; Vitamin B Complex | 2019 |
A 12-year Recurrence-free Survival After Multidisciplinary Treatment for a Patient With Combined Hepatocellular-Cholangiocarcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Carcinoma, Hepatocellular; Cholangiocarcinoma; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Gamma Rays; Hepatectomy; Humans; Liver Neoplasms; Middle Aged; Mitomycin; Tegafur; Uracil | 2019 |
Fluoropyrimidines and DPD testing: is there truly an inexorable link?
Topics: Antineoplastic Agents; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Fluorouracil; Genotype; Humans; Neoplasms; Oxonic Acid; Pharmacogenomic Testing; Phenotype; Point-of-Care Testing; Pyrrolidines; Tegafur; Thymine; Trifluridine; Uracil | 2019 |
Pharmacokinetics of S-1 monotherapy in plasma and in tears for gastric cancer patients.
Topics: Adult; Aged; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Oxonic Acid; Plasma; Prospective Studies; Pyridines; Stomach Neoplasms; Tears; Tegafur; Tissue Distribution | 2019 |
S-1 Monotherapy After Failure of Platinum Plus 5-Fluorouracil Chemotherapy in Recurrent or Metastatic Esophageal Carcinoma.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Salvage Therapy; Tegafur; Treatment Failure | 2019 |
Collagen gel droplet-embedded culture drug sensitivity test (CD-DST) predicts the effect of adjuvant chemotherapy on pancreatic cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Collagen; Drug Combinations; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fluorouracil; Gels; Humans; Male; Neoplasm Recurrence, Local; Oxonic Acid; Pancreatic Neoplasms; Predictive Value of Tests; Retrospective Studies; Survival Rate; Tegafur; Treatment Outcome | 2019 |
Fluoropyrimidine with or without platinum as first-line chemotherapy in patients with advanced gastric cancer and severe peritoneal metastasis: a multicenter retrospective study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Ascites; Cisplatin; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Malnutrition; Methotrexate; Middle Aged; Neutropenia; Organoplatinum Compounds; Oxonic Acid; Peritoneal Neoplasms; Progression-Free Survival; Pyridines; Retrospective Studies; Stomach Neoplasms; Tegafur; Treatment Outcome; Withholding Treatment; Young Adult | 2019 |
Lymph-node ratio is an important clinical determinant for selecting the appropriate adjuvant chemotherapy regimen for curative D2-resected gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Choice Behavior; Cisplatin; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Gastrectomy; Humans; Lymph Node Excision; Lymph Nodes; Male; Middle Aged; Neoplasm Staging; Oxaloacetates; Predictive Value of Tests; Prognosis; Retrospective Studies; Stomach Neoplasms; Survival Analysis; Tegafur; Uracil | 2019 |
[A Case Report of Luminal A Male Inflammatory Breast Cancer that Was Difficult to Treat Because of Trousseau Syndrome].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms, Male; Cilostazol; Combined Modality Therapy; Cyclophosphamide; Docetaxel; Drug Combinations; Epirubicin; Factor Xa Inhibitors; Fatal Outcome; Fluorouracil; Humans; Inflammatory Breast Neoplasms; Male; Oxonic Acid; Pyridines; Radiotherapy, Intensity-Modulated; Skin Neoplasms; Syndrome; Tegafur; Thiazoles; Thrombophilia | 2019 |
High-throughput method to analyze tegafur and 5-fluorouracil in human tears and plasma using hydrophilic interaction liquid chromatography/tandem mass spectrometry.
Topics: Aged; Chromatography, High Pressure Liquid; Female; Fluorouracil; Humans; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Male; Tandem Mass Spectrometry; Tears; Tegafur | 2019 |
Suppressive impact of metronomic chemotherapy using UFT and/or cyclophosphamide on mediators of breast cancer dissemination and invasion.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cyclophosphamide; Female; Fluorouracil; Humans; Mice; Mice, SCID; Neoplasm Invasiveness; Neovascularization, Pathologic; Tegafur; Uracil; Xenograft Model Antitumor Assays | 2019 |
Tegafur and 5-fluorouracil levels in tears and changes in tear volume in long-term users of the oral anticancer drug S-1.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Chromatography, Liquid; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Oxonic Acid; Quality of Life; Tandem Mass Spectrometry; Tears; Tegafur | 2019 |
Methylation of drug resistance-related genes in chemotherapy-sensitive Epstein-Barr virus-associated gastric cancer.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Line; Cisplatin; Cytoskeletal Proteins; DNA Methylation; DNA, Neoplasm; Drug Combinations; Drug Resistance, Neoplasm; Fluorouracil; Frizzled Receptors; Gene Silencing; Herpesvirus 4, Human; Humans; Male; Middle Aged; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Oxonic Acid; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Stomach Neoplasms; Tegafur; Tumor Protein p73 | 2020 |
Plasma microRNA profiles: identification of miR-1229-3p as a novel chemoresistant and prognostic biomarker in gastric cancer.
Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Survival; Disease-Free Survival; Drug Combinations; Drug Resistance, Neoplasm; Female; Fluorouracil; Gastrectomy; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Organic Anion Transporters, Sodium-Independent; Oxonic Acid; Prognosis; Proportional Hazards Models; Stomach Neoplasms; Tegafur | 2020 |
Role of Conversion Surgery for Unresectable Pancreatic Cancer After Long-Term Chemotherapy.
Topics: Aged; Albumins; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Gemcitabine; Humans; Irinotecan; Kaplan-Meier Estimate; Leucovorin; Lymph Node Excision; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Oxaliplatin; Oxonic Acid; Paclitaxel; Pancreatectomy; Pancreatic Neoplasms; Pancreaticoduodenectomy; Prognosis; Pyridines; Radiotherapy; Retrospective Studies; Tegafur; Time Factors | 2020 |
Population Pharmacokinetic Model-Based Evaluation of Circadian Variations in Plasma 5-Fluorouracil Concentrations During Long-Term Infusion in Rats: A Comparison With Oral Anticancer Prodrugs.
Topics: Administration, Oral; Animals; Fluorouracil; Prodrugs; Rats; Tegafur; Uracil | 2020 |
Joint Belgian recommendation on screening for DPD-deficiency in patients treated with 5-FU, capecitabine (and tegafur).
Topics: Antimetabolites, Antineoplastic; Belgium; Capecitabine; Dihydropyrimidine Dehydrogenase Deficiency; Fluorouracil; Humans; Tegafur | 2022 |
Simultaneous quantification method for 5-FU, uracil, and tegafur using UPLC-MS/MS and clinical application in monitoring UFT/LV combination therapy after hepatectomy.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Calibration; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Drug Monitoring; Fluorouracil; Hepatectomy; Humans; Leucovorin; Liver; Liver Neoplasms; Sensitivity and Specificity; Tandem Mass Spectrometry; Tegafur; Uracil | 2021 |
High L-Type Amino Acid Transporter 1 Levels Are Associated with Chemotherapeutic Resistance in Gastric Cancer Patients.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Combinations; Drug Resistance, Neoplasm; Female; Fluorouracil; Fusion Regulatory Protein-1; Humans; Immunohistochemistry; Large Neutral Amino Acid-Transporter 1; Male; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Phosphorylation; Prognosis; Prospective Studies; Stomach Neoplasms; Tegafur; TOR Serine-Threonine Kinases | 2021 |
Fluoropyridmidine use and hypertriglyceridemia among Japanese patients: analysis of adverse event database.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Fluorouracil; Humans; Hypertriglyceridemia; Japan; Tegafur | 2022 |
Successful Immunotherapy for Pancreatic Cancer in a Patient With TSC2 and SMAD4 Mutations: A Case Report.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; DNA Mutational Analysis; Drug Combinations; Drug Resistance, Neoplasm; Fluorouracil; High-Throughput Nucleotide Sequencing; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Mutation; Neoplasm Staging; Oxaliplatin; Oxonic Acid; Pancreatic Neoplasms; Prognosis; Programmed Cell Death 1 Receptor; Response Evaluation Criteria in Solid Tumors; Smad4 Protein; Tegafur; Tuberous Sclerosis Complex 2 Protein | 2021 |
S-1 facilitates canerpaturev (C-REV)-induced antitumor efficacy in a triple-negative breast cancer model.
Topics: Animals; Antimetabolites, Antineoplastic; CD8-Positive T-Lymphocytes; Drug Combinations; Fluorouracil; Humans; Mice; Neoplasm Recurrence, Local; Oncolytic Viruses; Oxonic Acid; Pyridines; Tegafur; Triple Negative Breast Neoplasms | 2021 |
[A Case Report for Peritoneal Recurrences by Laparoscopic Surgery after Colorectal Cancer Resection].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colonic Neoplasms; Colorectal Neoplasms; Female; Fluorouracil; Humans; Laparoscopy; Leucovorin; Peritoneal Neoplasms; Positron Emission Tomography Computed Tomography; Recurrence; Tegafur | 2022 |
A Pharmacokinetic-Pharmacodynamic Model Predicts Uracil-tegafur Effect on Tumor Shrinkage and Myelosuppression in a Colorectal Cancer Rat Model.
Topics: Administration, Oral; Animals; Colorectal Neoplasms; Fluorouracil; Rats; Tegafur; Uracil | 2023 |
Fluoropyrimidine usage in cases with hyperammonemia: real-world data study using the Japanese Adverse Drug Event Report (JADER) database.
Topics: Antimetabolites; Antineoplastic Agents; Capecitabine; Drug-Related Side Effects and Adverse Reactions; Fluorouracil; Humans; Hyperammonemia; Japan; Tegafur | 2023 |