fluorouracil and rifampin

fluorouracil has been researched along with rifampin in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19907 (28.00)18.7374
1990's2 (8.00)18.2507
2000's6 (24.00)29.6817
2010's10 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Clark, AM; Dunbar, DC; Muhammad, I; Takamatsu, S; Walker, LA1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Aponte, JC; Arevalo, J; Bustamante, JM; Castillo, D; Estevez, Y; Franzblau, SG; Gilman, RH; Gonzalez, G; Hammond, GB; Málaga, E; Pauli, GF; Quiliano, M; Sauvain, M; Tarleton, RL; Vaisberg, AJ; Verástegui, M; Wang, Y; Zimic, M1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ashenden, S; Bender, A; Cokol, M; Karakoc, I; Kuru, N; Mason, DJ; Meral, S; Stott, I; Weinstein, ZB1
Bernardino, AMR; Boechat, N; Dos Santos, MS; Faria, JV; Miguita, AGC; Vegi, PF1
Kanamoto, Y1
Theiss-Seuberling, HB1
Lovett, PS1
Goz, B; Prusoff, WH1
Pittillo, RF; Schabel, FM; Skipper, HE2
Harrington, EW; Trun, NJ1
Davis, WM; Waters, IW1
Dyckhoff, G; Haefeli, WE; Herold-Mende, C; Reuter, T; Rigalli, JP; Theile, D; Weiss, J1

Reviews

3 review(s) available for fluorouracil and rifampin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Recently reported biological activities of pyrazole compounds.
    Bioorganic & medicinal chemistry, 2017, 11-01, Volume: 25, Issue:21

    Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antineoplastic Agents; Antiviral Agents; Humans; Pyrazoles

2017
Pharmacology of viruses.
    Annual review of pharmacology, 1970, Volume: 10

    Topics: Amantadine; Animals; Antiviral Agents; Chick Embryo; Cytarabine; Fluorouracil; Guanidines; Haplorhini; Humans; Idoxuridine; Interferons; Nucleosides; Receptors, Drug; Rifampin; RNA, Transfer; RNA, Viral; Uracil; Viral Proteins; Virus Diseases; Viruses

1970

Other Studies

22 other study(ies) available for fluorouracil and rifampin

ArticleYear
Antimalarial, cytotoxic, and antifungal alkaloids from Duguetia hadrantha.
    Journal of natural products, 2001, Volume: 64, Issue:5

    Topics: Alkaloids; Animals; Antifungal Agents; Antimalarials; Antineoplastic Agents, Phytogenic; Brazil; Cell Adhesion; Cell Aggregation; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Paraguay; Plant Extracts; Plants, Medicinal; Plasmodium falciparum; Spectrophotometry, Ultraviolet; Tumor Cells, Cultured

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Trypanoside, anti-tuberculosis, leishmanicidal, and cytotoxic activities of tetrahydrobenzothienopyrimidines.
    Bioorganic & medicinal chemistry, 2010, Apr-15, Volume: 18, Issue:8

    Topics: Antiprotozoal Agents; Antitubercular Agents; Cell Line, Tumor; Humans; Mycobacterium tuberculosis; Parasitic Sensitivity Tests; Pyrimidines; Trypanosoma cruzi

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Prediction of Antibiotic Interactions Using Descriptors Derived from Molecular Structure.
    Journal of medicinal chemistry, 2017, 05-11, Volume: 60, Issue:9

    Topics: Anti-Bacterial Agents; Drug Interactions; Molecular Structure

2017
Effect of various anticancer agents on DNA polymerase.
    Gan, 1971, Volume: 62, Issue:2

    Topics: Adenosine Triphosphate; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Bone Marrow; Carcinoma, Hepatocellular; Cytosine Nucleotides; Dactinomycin; Deoxyribonucleotides; DNA Nucleotidyltransferases; DNA, Neoplasm; Fluorouracil; Guanosine Triphosphate; Liver; Liver Neoplasms; Liver Regeneration; Mitomycins; Neoplasms, Experimental; Rats; Rifampin; Thymidine; Tritium

1971
[Effect of x-rays and inhibitors of protein synthesis on the synthesis of chlorophyll and NADP-linked glyceraldehyde 3-phosphate dehydrogenase in greening Euglena gracilis].
    Archiv fur Mikrobiologie, 1973, Volume: 92, Issue:4

    Topics: Chloramphenicol; Chlorophyll; Chlorophyta; Dactinomycin; Darkness; Euglena gracilis; Fluorouracil; Glyceraldehyde-3-Phosphate Dehydrogenases; Light; NADP; Photosynthesis; Plant Proteins; Protein Biosynthesis; Radiation Effects; Rifampin; Time Factors; Transcription, Genetic

1973
Editorial: Drug targets in cancer chemotherapy.
    British medical journal, 1974, Dec-28, Volume: 4, Issue:5947

    Topics: Antineoplastic Agents; Dactinomycin; Doxorubicin; Enzyme Inhibitors; Fluorouracil; Isoenzymes; Methotrexate; Neoplasms; Rifampin

1974
Spontaneous auxotrophic and pigmented mutants occurring at high frequency in Bacillus pumilus NRRL B-3275.
    Journal of bacteriology, 1972, Volume: 112, Issue:2

    Topics: Acridines; Alkanesulfonates; Bacillus; Culture Media; Drug Resistance, Microbial; Erythromycin; Fluorouracil; L Forms; Lysogeny; Methylation; Mutagens; Mutation; Nitrosoguanidines; Pigments, Biological; Rifampin; Spectrophotometry; Streptomycin; Sulfates; Temperature; Transduction, Genetic; Tryptophan

1972
The "sensitivity" of resting and dividing cells.
    Klinika oczna, 1971, Volume: 41, Issue:5

    Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Bacillus cereus; Bacteriolysis; Carbenicillin; Cell Survival; Cephalothin; Chlortetracycline; Colistin; Daunorubicin; Enterococcus faecalis; Escherichia coli; Fluorouracil; Mechlorethamine; Mercaptopurine; Methotrexate; Microbial Sensitivity Tests; Nucleosides; Penicillins; Pseudomonas; Rifampin; Sarcina; Staphylococcus; Sulfonamides; Triazenes

1971
The "sensitivity" of resting and dividing cells.
    Cancer chemotherapy reports, 1970, Volume: 54, Issue:3

    Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Bacillus cereus; Bacteriolysis; Carbenicillin; Cell Survival; Cephalothin; Chlortetracycline; Colistin; Daunorubicin; Enterococcus faecalis; Escherichia coli; Fluorouracil; Imidazoles; Mechlorethamine; Mercaptopurine; Methotrexate; Microbial Sensitivity Tests; Nucleosides; Penicillins; Pseudomonas; Rifampin; Sarcina; Staphylococcus; Sulfonamides; Triazenes

1970
Unfolding of the bacterial nucleoid both in vivo and in vitro as a result of exposure to camphor.
    Journal of bacteriology, 1997, Volume: 179, Issue:7

    Topics: Camphor; Cell Division; Cephalexin; Chloramphenicol; Chromosomes, Bacterial; Escherichia coli; Fluorouracil; Microscopy, Fluorescence; Protein Synthesis Inhibitors; Rifampin; Temperature

1997
A new-drug roundup.
    RN, 1999, Volume: 62, Issue:4

    Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antitubercular Agents; Antiviral Agents; Capecitabine; Cyclopropanes; Deoxycytidine; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Etanercept; Fluorouracil; Humans; Immunoglobulin G; Isoxazoles; Leflunomide; Phosphodiesterase Inhibitors; Piperazines; Purines; Quinolines; Receptors, Tumor Necrosis Factor; Rifampin; Sildenafil Citrate; Sulfides; Sulfones; Thionucleotides

1999
Minor role of pregnane-x-receptor for acquired multidrug resistance in head and neck squamous cell carcinoma in vitro.
    Cancer chemotherapy and pharmacology, 2013, Volume: 71, Issue:5

    Topics: Antineoplastic Agents; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Head and Neck Neoplasms; Humans; Inhibitory Concentration 50; Paclitaxel; Pregnane X Receptor; Real-Time Polymerase Chain Reaction; Receptors, Steroid; Rifampin

2013