fluorouracil and platinum

fluorouracil has been researched along with platinum in 88 studies

Research

Studies (88)

TimeframeStudies, this research(%)All Research%
pre-19907 (7.95)18.7374
1990's11 (12.50)18.2507
2000's13 (14.77)29.6817
2010's29 (32.95)24.3611
2020's28 (31.82)2.80

Authors

AuthorsStudies
Atkins, LM; Glae, GR; Meischen, SJ; Smith, AB; Walker, EM1
Block, NL; Camuzzi, F; Claflin, A; Politano, VA; Stover, B; Troner, M1
Allegra, C; Jacob, J; Ozols, RF; Reed, E; Young, RC1
Egorin, MJ; Haraf, DJ; Mick, R; Moormeier, JA; Ratain, MJ; Vokes, EE; Weichselbaum, RR1
DeGregorio, MW; Denham, A; Gandara, DR; Perez, EA; Wiebe, VJ1
Atkinson, N; Castellanos, AM; Choksi, AJ; Dimery, IW; Felder, TB; Hong, WK; McCarthy, K; Newman, RA; Paredes, J; Robbins, KT1
Gang, M; Kline, I; Sirica, AE; Venditti, JM; Woodman, RJ1
deKernion, JB; Persky, L; Rose, D; Soloway, MS1
Asfaw, I; Buroker, T; Dindogru, A; Franklin, R; Hoschner, D; Knechtges, T; Leichman, L; Loh, JJ; Miller, P; Pietruk, T; Rosenberg, JC; Seydel, H; Steiger, Z; Torres, A; Vaishamapayan, G; Vaitkevicius, V; Wilson, RF1
Akman, S; Doroshow, JH; Hamasaki, V; Leong, L; Margolin, K; Morgan, R; Newman, E; Raschko, J; Somlo, G; Womack, E1
Fukushima, M; Hashimoto, T; Ishida, F; Kawakami, K; Matsu, T; Omura, K; Osari, A; Sunohara, T; Watanabe, Y; Yasuda, T1
Almadrones, L; Barakat, R; Curtin, J; Hakes, T; Hoskins, W; Jones, W; Lewis, JL; Markman, M; Reichman, B; Rubin, S1
Allain, P; Buquet-Fagot, C; Cvitkovic, E; Djelloul, S; Gespach, C; Louvet, C; Mester, J; Raymond, E1
Ikeda, K; Ishida, K; Iwaya, T; Kawamura, H; Koeda, K; Maesawa, C; Saito, K; Sato, N; Takagane, A; Takiyama, I; Terashima, M; Yoshinari, H1
Allain, P; Boisdron-Celle, M; Brienza, S; Cailleux, A; Cvitkovic, E; Gamelin, E; Krikorian, A; Larra, F; Lebouil, A; Robert, J; Turcant, A1
Allain, P; Boisdron-Celle, M; Bouil, AL; Brienza, S; Cailleux, A; Cvitkovic, E; Delva, R; Gamelin, E; Krikorian, A; Larra, F; Robert, J; Turcant, A1
Armand, JP; Cunningham, D; Kohne, CH; Misset, JL; van Cutsem, E1
Brès, J; Constans, B; Cupissol, D; Gau, F; Gory-Delabaere, G; Nouguier-Soulé, J1
Genvresse, I; Harder, H; Lange, C; Possinger, K; Schanz, J; Schweigert, M; Späth-Schwalbe, E1
Adjei, AA; Bruzek, LM; Davis, JN; Erlichman, C; Kaufmann, SH1
Kumada, K; Makuuchi, M; Midorikawa, T; Nemoto, H; Sanada, Y; Sasaya, S; Takeuchi, S; Takizawa, K; Uemichi, O; Yamaguchi, M; Yoshizawa, Y1
Brasnu, D; Hans, S; Laccourreye, H; Laccourreye, O; Ménard, M; Veivers, D1
Fuwa, N; Hayashi, N; Kano, M; Kawashima, M; Myojin, M; Nakamura, K; Ohnishi, H; Saijo, S; Shikama, N; Toita, T; Yamamoto, M1
Chang, HM; Choi, SJ; Kang, YK; Kim, TW; Kim, WK; Lee, JS; Park, YH; Ryu, BY1
Cho, HK; Chung, SJ; Kang, JH; Kim, DD; Kuh, HJ; Lee, ES; Lee, JW; Lee, KS; Park, JK; Shim, CK1
Iwazawa, T; Kanoh, T; Kimura, Y; Mizuno, H; Monden, T; Nakano, Y; Ohnishi, T; Shin, S; Shiozaki, K; Tono, T; Yano, K1
Cao, J; Chen, Z; Li, J; Lv, F; Zuo, Y1
Cunningham, D; Ghaneh, P; Neoptolemos, JP; Smith, CT; Starling, N; Sultana, A1
Ishibashi, K; Ishida, H; Miyazaki, T; Okada, N; Sano, M1
Li, J; Saif, MW1
Fareed, KR; Ilyas, M; Kaye, PV; Lobo, DN; Madhusudan, S; Parsons, SL; Soomro, IN1
Benasso, M; Erfán, J; Hitt, R; Kawecki, A; Licitra, L; Mesia, R; Remenár, É; Rivera, F; Rottey, S; Senger, S; Störkel, S; Stroh, C; Vermorken, JB; Zabolotnyy, D1
Kajiura, Y; Yagata, H; Yamauchi, H1
Fujii, M; Kaiga, T; Kanamori, N; Kochi, M; Mihara, Y; Okubo, R; Takayama, T1
Adenis, A; Conroy, T; Gavoille, C1
Kang, WK; Lee, J; Lim, HY; Park, JO; Park, SH; Park, YS; Yi, JH; Yim, DS1
Couvelard, A; Gillet, A; Goujon, G; Hammel, P; Hentic, O; Lévy, P; Maire, F; Palazzo, M; Rebours, V; Ruszniewski, P; Zappa, M1
Bengrine-Lefèvre, L; Bonnetain, F; Hammel, P; Hentic, O; Lévy, P; Louvet, C; Neuzillet, C; Raymond, E; Rebours, V; Rousseau, B; Ruszniewski, P1
Pavlidis, N1
Blair, E; Cohen, EE; Golden, DW; Haraf, DJ; Nwizu, T; Rudra, S; Stenson, KM; Vokes, EE; Witt, ME1
Bang, YJ; Choi, IS; Han, SW; Im, SA; Kang, EJ; Kim, JH; Kim, JS; Kim, JW; Kim, TY; Kim, YJ; Lee, JS; Lee, KW; Oh, DY1
Guan, W; Liu, B; Qian, X; Shen, J; Wang, H; Wei, J; Yu, L; Yue, G; Zou, Z1
Dzik, C; Guindalini, RS; Mak, MP; Takahashi, TK; Testa, L1
Boku, N; Esaki, T; Fujitani, K; Hamamoto, Y; Hironaka, S; Hyodo, I; Morita, S; Moriwaki, T; Nagase, M; Nishina, T; Okamoto, I; Shimodaira, H; Sugimoto, N; Tokunaga, S; Tsuda, M; Tsumura, T; Ueda, S; Ura, T; Yamaguchi, K; Yasui, H1
Ando, T; Fujinami, H; Horikawa, N; Hosokawa, A; Kajiura, S; Kobayashi, T; Mihara, H; Minemura, M; Nishikawa, J; Note, M; Ogawa, K; Sugiyama, T; Terada, M; Ueda, A; Yabushita, K; Yoshita, H1
Chen, X; Feng, J; Guan, X; Hong, Y; Song, H; Ye, J; You, X; Zheng, P1
Bai, Y; Chu, YP; Gong, JF; Li, J; Li, Y; Shen, L; Zhang, XT1
Alves, MP; Avezedo, I; de Mello, RA; Dinis, J; Gerós, S; Moreira, F1
Fang, W; Jiang, H; Mao, C; Qian, J; Xu, N; Zhang, X; Zhao, P; Zheng, Y1
Bail, JP; Brigand, C; Collet, D; Gronnier, C; Lebreton, G; Luc, G; Mabrut, JY; Mariette, C; Meunier, B1
Adkins, D; Aguilar, JL; Bryant, K; Chang, SC; Chen, E; Chin, S; Ernst, S; He, S; Lee, HJ; Misiukiewicz, K; Obasaju, CK; Soulières, D1
Binder, M; Bokemeyer, C; Braig, F; Busch, CJ; Grob, T; Knecht, R; Kriegs, M; Laban, S; Schieferdecker, A; Voigtlaender, M1
Bu, Z; Hu, Y; Ji, J; Jia, Y; Li, S; Li, Z; Miao, R; Shan, F; Wu, A; Xiao, A; Xing, X; Xing, Z; Xue, K; Zhang, L1
Cadeddu, C; Deidda, M; Demurtas, L; Madeddu, C; Mercuro, G; Piras, A; Piscopo, G; Puzzoni, M; Scartozzi, M1
Bozkaya, Y; Demirci, NS; Erdem, GU; Ozdemir, NY; Yazici, O; Zengin, N1
Ahsan, H; Ali, SS; Khan, FH; Rehman, AA; Siddiqui, T; Zia, MK1
Black-Shinn, J; Boyd, M; Chirovsky, D; Joo, S; Nadler, E1
Beedu, SR; Godugu, D1
Cao, Y; Chang, Q; Chen, EX; Hedley, D; Ornatsky, O; Zhang, W1
Bouvet, M; Clary, B; Han, Q; Higuchi, T; Hoffman, RM; Park, JH; Singh, SR; Sugisawa, N; Tan, Y; Yamamoto, J; Yoon, SN; Zhao, M1
Aprile, G; Brandi, G; Brieau, B; Casadei-Gardini, A; Dahan, L; Evesque, L; Filippi, R; Le Sourd, S; Lièvre, A; Lonardi, S; Meurisse, A; Neuzillet, C; Pointet, AL; Rousseau, B; Scartozzi, M; Silvestris, N; Tougeron, D; Vernerey, D; Vienot, A; Vivaldi, C1
Chen, X; Ding, H; Ding, J; Luo, D; Wang, L; Wei, Y; Xiong, Y; Yi, F; Zhang, W1
Ji, LN; Mao, ZW; Muhammad, N; Nasreen, S; Nawaz, U; Tan, CP; Wang, FX; Wang, J1
Luo, Y; Pei, S; Xiao, Y; Xu, J; Zhu, X1
Hwang, M; Seiwert, TY1
Cavalieri, S; Licitra, L1
Honma, Y; Ishiki, H; Kosaka, M1
Auperin, A; Bourhis, J; Fraslin, A; Guigay, J; Keilholz, U; Mesia, R1
Cortes-Bullich, A; Gonzalez-Perez, A; Lopez-Bigas, N; Muiños, F; Pich, O; Pratcorona, M1
Demachi, K; Fujita, T; Fujiwara, H; Kojima, T; Kotani, D; Okunaka, M; Sakashita, S; Yoshino, T1
Chen, C; Ding, SR; Glorieux, C; Huang, P; Huang, ZL; Li, H; Li, XH; Liu, SR; Tao, YL; Wang, GN; Wang, HB; Wei, YH; Wu, YF; Xia, YF; Zheng, SH1
Crowley, JD; Hartinger, CG; Lisboa, LS; McAdam, CJ; Preston, D; Wright, LJ1
But, B; Chan, ATC; Chappell, RJ; Cheng, AC; Choi, CW; Kwong, DLW; Lee, AWM; Lee, S; Lu, TX; Ng, WT; Ngan, RKC; Tung, S; Wong, F; Yiu, H; Yuen, KT1
Bellile, E; Bradford, CR; Carey, TE; Casper, K; Chinn, SB; Dragovic, AF; Eisbruch, A; Jolly, S; Kupfer, R; Malloy, KM; Mierzwa, ML; Prince, ME; Shuman, AG; Spector, ME; Srinivasan, A; Stucken, C; Swiecicki, PL; Wolf, GT; Worden, FP1
Cho, MS; Cho, SY; Huh, YJ; Lee, JH; Lee, KE1
Hu, Y; Tang, C; Wei, X; Yuwen, D; Zhang, J; Zhang, W; Zhu, X; Zhu, Y1
Gao, LL; Li, H; Sun, Y; Tang, YF; Zhao, Z1
Alati, A; Bibault, JE; Charles-Nelson, A; Durdux, C; Fabiano, E; Geiss, R; Giraud, P; Housset, M; Kreps, S; Mareau, A; Méjean, A1
Hirota, M; Kawada, J; Kawakami, H; Kii, T; Kurokawa, Y; Matsuyama, J; Nomura, M; Ohta, T; Sakai, D; Satoh, T; Shimokawa, T; Tsujinaka, T1
Akimoto, T; Daiko, H; Fujita, T; Fujiwara, H; Hojo, H; Ito, R; Kojima, T; Nakamura, N; Nakamura, Y; Sunakawa, H; Yano, T; Yoshino, T1
Guo, Z; Jia, Y; Song, R; Wu, C; Zhang, R; Zhang, S; Zhang, X; Zhao, Y1
Enzinger, PC; Guo, H; Joo, S; Meng, Y; Qu, T; Zhang, S; Zhong, Y1
Fujii, T; Fujimoto, Y; Gumuscu, B; Hanai, N; Hara, H; Matsumoto, K; Mitsugi, K; Nakayama, M; Nohata, N; Oridate, N; Shiga, K; Shimizu, Y; Swaby, RF; Tahara, M; Takahashi, K; Takahashi, M; Takahashi, S; Tanaka, K; Ueda, T; Yamaguchi, H; Yamazaki, T; Yasumatsu, R; Yokota, T; Yoshizaki, T1
Li, C; Li, X; Shen, L; Wang, S; Wang, T; Zhai, J1
Colevas, AD; Coty, J; Hara, W; Jun, M; Le, QT; Lira, R; Lu, R; McMillan, A; Pinto, H; Quon, A; Winters, E1
Nowak, D; Quartucci, C; Rakete, S; Rooney, JPK1
Brossart, P; Feldmann, G; Gonzalez-Carmona, MA; Jafari, A; Kalff, JC; Köksal, M; Lingohr, P; Mahn, R; Mańczak, A; Möhring, C; Monin, MB; Sadeghlar, F; Sarria, GR; Sommer, N; Strassburg, CP; Timotheou, A; Toma, M; Zhou, T1
Bonomo, P; Borcoman, E; Cau, MC; Depenni, R; Ghi, MG; Ghiani, M; Le Tourneau, C; Leo, L; Messinger, D; Montesarchio, V; Ronzino, G; Salmio, S; Sbrana, A; Schulten, J1

Reviews

11 review(s) available for fluorouracil and platinum

ArticleYear
Fluorouracil and leucovorin in advanced breast cancer.
    Advances in experimental medicine and biology, 1993, Volume: 339

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Female; Fluorouracil; Humans; Leucovorin; Platinum

1993
Clinical advances with topoisomerase I inhibitors in gastrointestinal malignancies.
    Anti-cancer drugs, 1999, Volume: 10 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Docetaxel; Enzyme Inhibitors; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Platinum; Quinazolines; Taxoids; Thiophenes; Topoisomerase I Inhibitors

1999
A multi-institutional survey of the effectiveness of chemotherapy combined with radiotherapy for patients with nasopharyngeal carcinoma.
    Japanese journal of clinical oncology, 2004, Volume: 34, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Data Collection; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Nasopharyngeal Neoplasms; Platinum; Radiotherapy Dosage; Survival Rate; Treatment Outcome

2004
Current strategy for triple-negative breast cancer: appropriate combination of surgery, radiation, and chemotherapy.
    Breast cancer (Tokyo, Japan), 2011, Volume: 18, Issue:3

    Topics: Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Cyclophosphamide; Docetaxel; Epirubicin; Female; Fluorouracil; Humans; Mastectomy, Segmental; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Platinum; Receptors, Estrogen; Taxoids

2011
Metastatic pancreatic cancer: old drugs, new paradigms.
    Current opinion in oncology, 2011, Volume: 23, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Pancreatic Ductal; Clinical Trials, Phase III as Topic; Deoxycytidine; Erlotinib Hydrochloride; Fluorouracil; Gemcitabine; Heparin; Humans; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Pancreatic Neoplasms; Platinum; Quinazolines

2011
Concurrent chemoradiotherapy comparison of taxanes and platinum versus 5-fluorouracil and platinum in nasopharyngeal carcinoma treatment.
    Chinese medical journal, 2014, Volume: 127, Issue:1

    Topics: Carcinoma; Chemoradiotherapy; Fluorouracil; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Platinum; Taxoids; Treatment Outcome

2014
Pathophysiology of cardiotoxicity induced by nonanthracycline chemotherapy.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2016, Volume: 17 Suppl 1 Special issue on Cardiotoxicity fr

    Topics: Anthracyclines; Anti-Bacterial Agents; Antineoplastic Agents, Alkylating; Cardiotoxicity; Fluorouracil; Heart Failure; Humans; Neoplasms; Oxidative Stress; Platinum; Stroke Volume; Taxoids; Ventricular Dysfunction, Left

2016
Chemotherapeutic Drugs and Plasma Proteins: Exploring New Dimensions.
    Current protein & peptide science, 2018, Volume: 19, Issue:10

    Topics: Antineoplastic Agents; Blood Proteins; Cell Survival; Cisplatin; Coordination Complexes; Fluorouracil; Humans; Neoplasms; Platinum; Ruthenium

2018
Comparison of Platinum/S-1 and Platinum/5-Fluorouracil as First-Line Chemotherapy for Advanced Gastric or Gastroesophageal Junction Cancer: A Meta-Analysis Based on Randomized Controlled Trials.
    Chemotherapy, 2020, Volume: 65, Issue:1-2

    Topics: Antineoplastic Agents; Coordination Complexes; Disease-Free Survival; Drug Combinations; Drug Therapy, Combination; Esophagogastric Junction; Fluorouracil; Gastrointestinal Neoplasms; Humans; Neoplasm Staging; Oxonic Acid; Platinum; Proportional Hazards Models; Randomized Controlled Trials as Topic; Stomach Neoplasms; Survival Analysis; Tegafur; Treatment Outcome

2020
Comparison of Efficacy and Safety of Taxanes Plus Platinum and Fluorouracil Plus Platinum in the First-Line Treatment of Esophageal Cancer: A Systematic Review and Meta-Analysis.
    Current oncology (Toronto, Ont.), 2022, 09-16, Volume: 29, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Esophageal Neoplasms; Fluorouracil; Humans; Leukopenia; Lung Neoplasms; Platinum; Taxoids; Thrombocytopenia

2022
The optimal neoadjuvant chemotherapy regimen for locally advanced gastric and gastroesophageal junction adenocarcinoma: a systematic review and Bayesian network meta-analysis.
    European journal of medical research, 2022, Nov-09, Volume: 27, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Chemotherapy, Adjuvant; Esophagogastric Junction; Fluorouracil; Humans; Neoadjuvant Therapy; Network Meta-Analysis; Platinum; Stomach Neoplasms; Taxoids

2022

Trials

16 trial(s) available for fluorouracil and platinum

ArticleYear
5-Fluorouracil, leucovorin, hydroxyurea, and escalating doses of continuous-infusion cisplatin with concomitant radiotherapy: a clinical and pharmacologic study.
    Cancer chemotherapy and pharmacology, 1992, Volume: 29, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Leucovorin; Lung Neoplasms; Male; Middle Aged; Platinum

1992
Prospective randomized trial of high-dose cisplatin and fluorouracil infusion with or without sodium diethyldithiocarbamate in recurrent and/or metastatic squamous cell carcinoma of the head and neck.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Ditiocarb; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kidney; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Platinum; Prospective Studies; Random Allocation

1988
Pharmacokinetics of cisplatin in combined cisplatin and 5-fluorouracil therapy: a comparative study of three different schedules of cisplatin administration.
    Japanese journal of clinical oncology, 1998, Volume: 28, Issue:3

    Topics: Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Esophageal Neoplasms; Female; Fluorouracil; Humans; Kidney; Male; Middle Aged; Platinum; Stomach Neoplasms

1998
Determination of unbound platinum after oxaliplatin administration: comparison of currently available methods and influence of various parameters.
    Anti-cancer drugs, 1998, Volume: 9, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorouracil; Humans; Leucovorin; Organoplatinum Compounds; Oxaliplatin; Platinum; Regression Analysis

1998
Cumulative pharmacokinetic study of oxaliplatin, administered every three weeks, combined with 5-fluorouracil in colorectal cancer patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Half-Life; Humans; Infusions, Intravenous; Leucovorin; Mass Spectrometry; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Platinum; Regression Analysis; Sensitivity and Specificity

1997
Phase II study of paclitaxel and carboplatin in advanced gastric cancer previously treated with 5-fluorouracil and platinum.
    Japanese journal of clinical oncology, 2005, Volume: 35, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Drug Administration Schedule; Endpoint Determination; Female; Fluorouracil; Humans; Male; Middle Aged; Nervous System Diseases; Neutropenia; Paclitaxel; Platinum; Stomach Neoplasms

2005
Clinical pharmacokinetics of oxaliplatin and 5-fluorouracil administered in combination with leucovorin in Korean patients with advanced colorectal cancer.
    Journal of cancer research and clinical oncology, 2006, Volume: 132, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Creatinine; Female; Fluorouracil; Humans; Korea; Leucovorin; Male; Metabolic Clearance Rate; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Platinum

2006
Evaluation of EGFR gene copy number as a predictive biomarker for the efficacy of cetuximab in combination with chemotherapy in the first-line treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck: EXTREME study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:5

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cetuximab; ErbB Receptors; Fluorouracil; Gene Dosage; Head and Neck Neoplasms; Humans; Neoplasm Metastasis; Neoplasm Recurrence, Local; Platinum; Survival Analysis; Treatment Outcome; Young Adult

2011
Randomised phase II trial of docetaxel and sunitinib in patients with metastatic gastric cancer who were previously treated with fluoropyrimidine and platinum.
    British journal of cancer, 2012, Apr-24, Volume: 106, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Docetaxel; Female; Fluorouracil; Humans; Indoles; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Platinum; Pyrroles; Salvage Therapy; Stomach Neoplasms; Sunitinib; Survival Rate; Taxoids; Tissue Distribution; Treatment Outcome; Young Adult

2012
Randomized, open-label, phase III study comparing irinotecan with paclitaxel in patients with advanced gastric cancer without severe peritoneal metastasis after failure of prior combination chemotherapy using fluoropyrimidine plus platinum: WJOG 4007 tria
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Dec-10, Volume: 31, Issue:35

    Topics: Adult; Aged; Anemia; Anorexia; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Kaplan-Meier Estimate; Male; Middle Aged; Neutropenia; Paclitaxel; Platinum; Prospective Studies; Stomach Neoplasms; Treatment Failure; Treatment Outcome

2013
A phase II study of triweekly paclitaxel and capecitabine combination therapy in patients with fluoropyrimidine-platinum-resistant metastatic gastric adenocarcinoma.
    Journal of cancer research and therapeutics, 2013, Volume: 9 Suppl

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Male; Middle Aged; Paclitaxel; Platinum; Pyrimidines; Stomach Neoplasms

2013
Biweekly S-1 plus paclitaxel (SPA) as second-line chemotherapy after failure from fluoropyrimidine and platinum in advanced gastric cancer: a phase II study.
    Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:3

    Topics: Administration, Oral; Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Asian People; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Injections, Intravenous; Male; Middle Aged; Neutropenia; Oxonic Acid; Paclitaxel; Platinum; Stomach Neoplasms; Tegafur; Treatment Outcome

2014
Cetuximab plus platinum-based chemotherapy in head and neck squamous cell carcinoma: a randomized, double-blind safety study comparing cetuximab produced from two manufacturing processes using the EXTREME study regimen.
    BMC cancer, 2016, Jan-14, Volume: 16

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Chemistry, Pharmaceutical; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Platinum; Squamous Cell Carcinoma of Head and Neck

2016
Randomized trial of laryngeal organ preservation evaluating two cycles of induction chemotherapy with platinum, docetaxel, and a novel Bcl-xL inhibitor.
    Head & neck, 2022, Volume: 44, Issue:7

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Fluorouracil; Humans; Induction Chemotherapy; Laryngeal Neoplasms; Organ Preservation; Platinum; Proto-Oncogene Proteins c-bcl-2

2022
A phase II study of S-1 therapy for patients with advanced and recurrent esophageal cancer resistant or intolerable to fluorouracil, platinum, and taxane therapy (OGSG 1404).
    Esophagus : official journal of the Japan Esophageal Society, 2022, Volume: 19, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Fluorouracil; Humans; Neoplasm Recurrence, Local; Platinum; Taxoids

2022
First-line pembrolizumab ± chemotherapy for recurrent/metastatic head and neck cancer: Japanese subgroup of KEYNOTE-048.
    International journal of clinical oncology, 2022, Volume: 27, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Fluorouracil; Head and Neck Neoplasms; Humans; Japan; Neoplasm Recurrence, Local; Platinum; Squamous Cell Carcinoma of Head and Neck

2022

Other Studies

61 other study(ies) available for fluorouracil and platinum

ArticleYear
Combination chemotherapy of L1210 leukemia with platinum compounds and cyclophosphamide plus other selected antineoplastic agents.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:6

    Topics: Animals; Cell Survival; Cisplatin; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fluorouracil; Leukemia L1210; Mesylates; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Organometallic Compounds; Platinum; Propylamines; Vincristine

1976
Further experience with chemotherapy in the Dunning prostatic adenocarcinoma.
    Transactions of the American Association of Genito-Urinary Surgeons, 1978, Volume: 70

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Hybridization, Genetic; Hydroxyurea; Lomustine; Male; Methotrexate; Neoplasms, Experimental; Platinum; Prostatic Neoplasms; Rats

1978
5-Fluorouracil (5-FU) and leucovorin in platinum-refractory advanced stage ovarian carcinoma.
    Gynecologic oncology, 1992, Volume: 46, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Drug Administration Schedule; Drug Resistance; Female; Fluorouracil; Humans; Leucovorin; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Platinum; Remission Induction

1992
Pharmacokinetics of cisplatin in patients receiving interleukin-2-containing treatment regimens.
    Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Creatinine; Fluorouracil; Humans; Interleukin-2; Metabolic Clearance Rate; Neoplasms; Platinum

1989
The enhanced therapeutic effect of cis-platinum (II) diamminodichloride against L1210 leukemia when combined with cyclophosphamide or 1,2-bis(3,5-dioxopiperazine-1-yl)propane or several other antitumor agents.
    Chemotherapy, 1973, Volume: 18, Issue:3

    Topics: Amines; Animals; Antineoplastic Agents; Azacitidine; Camptothecin; Carmustine; Chlorides; Cyclophosphamide; Cytarabine; Drug Synergism; Emetine; Fluorouracil; Ketones; Leukemia L1210; Male; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Piperazines; Platinum; Propane; Time Factors

1973
Effect of chemotherapeutic agents on bladder cancer: a new animal model.
    Surgical forum, 1973, Volume: 24

    Topics: Animals; Antineoplastic Agents; Carcinoma, Transitional Cell; Cyclophosphamide; Dactinomycin; Diamines; Disease Models, Animal; Doxorubicin; Fluorouracil; Hydroxyurea; Lomustine; Mice; Mice, Inbred C3H; Platinum; Urinary Bladder Neoplasms

1973
Eradication and palliation of squamous cell carcinoma of the esophagus with chemotherapy, radiotherapy, and surgical therapy.
    The Journal of thoracic and cardiovascular surgery, 1981, Volume: 82, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Esophageal Neoplasms; Esophagus; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycins; Platinum

1981
[Pharmacokinetics and changes of reduced folate levels in tumor after administration of cisplatin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:6

    Topics: Animals; Cisplatin; Dose-Response Relationship, Drug; Fluorouracil; Formaldehyde; Male; Platinum; Rats; Sarcoma, Yoshida; Tetrahydrofolates

1994
Mitomycin-C plus a 3-day continuous intravenous infusion of 5-fluorouracil: an inactive salvage regimen for platinum-resistant ovarian carcinoma.
    Gynecologic oncology, 1993, Volume: 50, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Resistance; Female; Fluorouracil; Humans; Infusions, Intravenous; Middle Aged; Mitomycin; Ovarian Neoplasms; Platinum; Salvage Therapy

1993
Antitumor activity of oxaliplatin in combination with 5-fluorouracil and the thymidylate synthase inhibitor AG337 in human colon, breast and ovarian cancers.
    Anti-cancer drugs, 1997, Volume: 8, Issue:9

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Cell Survival; Colonic Neoplasms; DNA, Neoplasm; Enzyme Inhibitors; Female; Fluorouracil; Humans; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Platinum; Thymidylate Synthase; Tumor Cells, Cultured

1997
[Pharmacologic markers predictive of neutropenia chemically induced by cisplatin (CDDP)].
    Journal de la Societe de biologie, 1999, Volume: 193, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Choriocarcinoma; Cisplatin; DNA Adducts; Drug Monitoring; Female; Fluorouracil; Humans; Lymphocytes; Male; Middle Aged; Neoplasms; Neutropenia; Ovarian Neoplasms; Platinum; Predictive Value of Tests; Saliva

1999
Tolerability of the cytoprotective agent amifostine in elderly patients receiving chemotherapy: a comparative study.
    Anti-cancer drugs, 2001, Volume: 12, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Amifostine; Antihypertensive Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cyclophosphamide; Deoxycytidine; Doxorubicin; Epirubicin; Esophageal Neoplasms; Female; Fluorouracil; Gemcitabine; Humans; Hypertension; Hypocalcemia; Hypotension; Infusions, Intravenous; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; Nausea; Paclitaxel; Pancreatic Neoplasms; Platinum; Prednisone; Premedication; Retrospective Studies; Vincristine

2001
Synergy of the protein farnesyltransferase inhibitor SCH66336 and cisplatin in human cancer cell lines.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:5

    Topics: Alkyl and Aryl Transferases; Antineoplastic Agents; Apoptosis; Cell Cycle; Cisplatin; DNA Adducts; Drug Combinations; Drug Synergism; Fluorouracil; Humans; Melphalan; Piperidines; Platinum; Pyridines; Tumor Cells, Cultured

2001
[Tissue platinum distribution and the effect following intra-arterial injection of cisplatin to metastatic liver cancer--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:8

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Esophageal Neoplasms; Fluorouracil; Hepatic Artery; Humans; Injections, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Platinum; Tissue Distribution

2001
Chemotherapy alone with curative intent in patients with invasive squamous cell carcinoma of the pharyngolarynx classified as T1-T4N0M0 complete clinical responders.
    Cancer, 2001, Sep-15, Volume: 92, Issue:6

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Fluorouracil; Humans; Laryngeal Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Neoplasms, Second Primary; Pharyngeal Neoplasms; Platinum; Salvage Therapy

2001
[FOLFOX 4 in a patient with metastatic colorectal cancer on hemodialysis due to chronic renal failure].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Routes; Female; Fluorouracil; Humans; Kidney Failure, Chronic; Leucovorin; Organoplatinum Compounds; Oxaliplatin; Platinum; Renal Dialysis; Sigmoid Neoplasms

2007
Primary small intestinal malignant tumors: survival analysis of 48 postoperative patients.
    Journal of clinical gastroenterology, 2008, Volume: 42, Issue:2

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Female; Fluorouracil; Follow-Up Studies; Humans; Intestinal Neoplasms; Intestine, Small; Male; Middle Aged; Platinum; Prognosis; Proportional Hazards Models; Survival Analysis

2008
Gemcitabine based combination chemotherapy in advanced pancreatic cancer-indirect comparison.
    BMC cancer, 2008, Jul-08, Volume: 8

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Clinical Trials, Phase III as Topic; Deoxycytidine; Drug Administration Schedule; Fluorouracil; Gemcitabine; Humans; Irinotecan; Meta-Analysis as Topic; Pancreatic Neoplasms; Platinum; Proportional Hazards Models; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome

2008
[Changes in peripheral neuropathy and platinum concentrations in patients undergoing surgery following modified FOLFOX6 therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Erythrocyte Count; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Peripheral Nervous System Diseases; Platinum

2008
Any progress in the management of advanced pancreatic cancer? Highlights from the 45th ASCO annual meeting. Orlando, FL, USA. May 29-June 2, 2009.
    JOP : Journal of the pancreas, 2009, Jul-06, Volume: 10, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Clinical Trials as Topic; Deoxycytidine; Erlotinib Hydrochloride; Fluorouracil; Gemcitabine; Humans; Irinotecan; Leucovorin; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Platinum; Quinazolines; Treatment Outcome

2009
Tumour regression grade (TRG) analyses in patients with resectable gastro-oesophageal adenocarcinomas treated with platinum-based neoadjuvant chemotherapy.
    Histopathology, 2009, Volume: 55, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cisplatin; Combined Modality Therapy; Deoxycytidine; Dose-Response Relationship, Drug; Epirubicin; Esophageal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Platinum; Remission Induction; Retrospective Studies; Single-Blind Method; Stomach Neoplasms; Treatment Outcome

2009
Pharmacokinetics of oxaliplatin in gastrointestinal cancer patients with malignant ascites.
    Journal of chemotherapy (Florence, Italy), 2011, Volume: 23, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Ascites; Ascitic Fluid; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Infusions, Intravenous; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Platinum

2011
FOLFIRI regimen: an effective second-line chemotherapy after failure of etoposide-platinum combination in patients with neuroendocrine carcinomas grade 3.
    Endocrine-related cancer, 2012, Volume: 19, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Camptothecin; Carcinoma, Neuroendocrine; Disease-Free Survival; Etoposide; Female; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Grading; Pancreatic Neoplasms; Pelvic Neoplasms; Platinum; Treatment Outcome

2012
FOLFIRI regimen in metastatic pancreatic adenocarcinoma resistant to gemcitabine and platinum-salts.
    World journal of gastroenterology, 2012, Sep-07, Volume: 18, Issue:33

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Deoxycytidine; Disease Progression; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Fluorouracil; Gemcitabine; Humans; Leucovorin; Male; Middle Aged; Pancreatic Neoplasms; Platinum; Retrospective Studies; Survival Rate; Treatment Failure; Treatment Outcome

2012
Optimal therapeutic management of patients with distinct clinicopathological cancer of unknown primary subsets.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23 Suppl 10

    Topics: Adenocarcinoma; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Fluorouracil; Humans; Lymphatic Metastasis; Neoplasms, Unknown Primary; Platinum; Prognosis; Taxoids; Treatment Outcome

2012
Outcomes of induction chemotherapy followed by concurrent chemoradiation for nasopharyngeal carcinoma.
    Oral oncology, 2013, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemoradiotherapy; Chemotherapy, Adjuvant; Child; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Hydroxyurea; Induction Chemotherapy; Male; Middle Aged; Nasopharyngeal Neoplasms; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Platinum; Radiotherapy Dosage; Remission Induction; Survival Rate; Treatment Outcome; Young Adult

2013
Irinotecan combined with 5-fluorouracil and leucovorin third-line chemotherapy after failure of fluoropyrimidine, platinum, and taxane in gastric cancer: treatment outcomes and a prognostic model to predict survival.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2013, Volume: 16, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Camptothecin; Carcinoma, Signet Ring Cell; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Platinum; Retrospective Studies; Salvage Therapy; Stomach Neoplasms; Survival Rate; Taxoids; Treatment Outcome

2013
Synergistic anticancer effects of polyphyllin I and evodiamine on freshly-removed human gastric tumors.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Confidence Intervals; Diosgenin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Irinotecan; Male; Middle Aged; Neoplasm Proteins; Platinum; Quinazolines; RNA, Messenger; Stomach Neoplasms

2013
Multiagent chemotherapy for metastatic adenocarcinoma of the seminal vesicle.
    Anti-cancer drugs, 2014, Volume: 25, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Genital Neoplasms, Male; Humans; Leucovorin; Male; Organoplatinum Compounds; Palliative Care; Platinum; Seminal Vesicles

2014
Non-randomized comparison between irinotecan plus mitomycin C and irinotecan alone in patients with advanced gastric cancer refractory to fluoropyrimidine and platinum.
    Anticancer research, 2013, Volume: 33, Issue:11

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Resistance, Neoplasm; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Male; Middle Aged; Mitomycin; Neoplasm Metastasis; Neoplasm Staging; Platinum; Prognosis; Salvage Therapy; Stomach Neoplasms; Survival Rate

2013
Cetuximab plus platinum-based chemotherapy in head and neck squamous cell carcinoma: a retrospective study in a single comprehensive European cancer institution.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Disease-Free Survival; Europe; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Grading; Platinum; Retrospective Studies; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome

2014
Predictive Factors of Recurrence in Patients with Pathological Complete Response After Esophagectomy Following Neoadjuvant Chemoradiotherapy for Esophageal Cancer: A Multicenter Study.
    Annals of surgical oncology, 2015, Volume: 22 Suppl 3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; Combined Modality Therapy; Esophageal Neoplasms; Esophagectomy; Female; Fluorouracil; Follow-Up Studies; France; Humans; Incidence; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Platinum; Prognosis; Retrospective Studies; Survival Rate

2015
Liquid biopsy monitoring uncovers acquired RAS-mediated resistance to cetuximab in a substantial proportion of patients with head and neck squamous cell carcinoma.
    Oncotarget, 2016, Jul-12, Volume: 7, Issue:28

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Line, Tumor; Cetuximab; Drug Resistance, Neoplasm; ErbB Receptors; Fluorouracil; GTP Phosphohydrolases; Head and Neck Neoplasms; High-Throughput Nucleotide Sequencing; Humans; Liquid Biopsy; Membrane Proteins; Mutation; Platinum; Proto-Oncogene Proteins p21(ras); ras Proteins

2016
ABCC2-24C > T polymorphism is associated with the response to platinum/5-Fu-based neoadjuvant chemotherapy and better clinical outcomes in advanced gastric cancer patients.
    Oncotarget, 2016, Aug-23, Volume: 7, Issue:34

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Genotype; Humans; Male; Middle Aged; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoadjuvant Therapy; Platinum; Polymorphism, Single Nucleotide; Stomach Neoplasms

2016
5-fluorouracil, leucovorin, and irinotecan (FOLFIRI) as a third-line chemotherapy treatment in metastatic gastric cancer, after failure of fluoropyrimidine, platinum, anthracycline, and taxane.
    Bosnian journal of basic medical sciences, 2018, May-20, Volume: 18, Issue:2

    Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Disease-Free Survival; Female; Fluorine; Fluorouracil; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Patient Safety; Platinum; Pyrimidines; Stomach Neoplasms; Taxoids; Treatment Outcome

2018
Treatment patterns and outcomes among patients with recurrent/metastatic squamous cell carcinoma of the head and neck.
    Future oncology (London, England), 2019, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Platinum; Practice Patterns, Physicians'; Squamous Cell Carcinoma of Head and Neck; Survival Analysis; Treatment Outcome

2019
Synthesis, characterisation and anti-tumour activity of biopolymer based platinum nanoparticles and 5-fluorouracil loaded platinum nanoparticles.
    IET nanobiotechnology, 2019, Volume: 13, Issue:3

    Topics: Antineoplastic Agents; Biological Assay; Biopolymers; Drug Carriers; Fluorouracil; Metal Nanoparticles; Platinum

2019
Skin platinum deposition in colorectal cancer patients following oxaliplatin-based therapy.
    Cancer chemotherapy and pharmacology, 2019, Volume: 84, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Colorectal Neoplasms; Female; Fluorouracil; Heavy Metal Poisoning, Nervous System; Humans; Leucovorin; Limit of Detection; Male; Mass Spectrometry; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Peripheral Nervous System Diseases; Platinum; Skin

2019
Oral recombinant methioninase combined with oxaliplatinum and 5-fluorouracil regressed a colon cancer growing on the peritoneal surface in a patient-derived orthotopic xenograft mouse model.
    Tissue & cell, 2019, Volume: 61

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carbon-Sulfur Lyases; Cell Proliferation; Colonic Neoplasms; Fluorescence; Fluorouracil; Humans; Mice, Nude; Peritoneum; Platinum; Recombinant Proteins; Time Factors; Treatment Outcome; Xenograft Model Antitumor Assays

2019
Fluropyrimidine single agent or doublet chemotherapy as second line treatment in advanced biliary tract cancer.
    International journal of cancer, 2020, 12-01, Volume: 147, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Capecitabine; Female; Fluorouracil; France; Humans; Irinotecan; Italy; Male; Middle Aged; Platinum; Prospective Studies; Pyrimidines; Retrospective Studies; Survival Analysis; Treatment Outcome

2020
Multiaction Platinum(IV) Prodrug Containing Thymidylate Synthase Inhibitor and Metabolic Modifier against Triple-Negative Breast Cancer.
    Inorganic chemistry, 2020, Sep-08, Volume: 59, Issue:17

    Topics: Apoptosis; Cell Line, Tumor; Coordination Complexes; DNA Damage; Drug Liberation; Enzyme Inhibitors; Fluorouracil; Humans; Intracellular Space; Mitochondria; Platinum; Prodrugs; Reactive Oxygen Species; Thymidylate Synthase; Transcription, Genetic; Triple Negative Breast Neoplasms

2020
Combined chemotherapy of platinum and fluorouracil promotes T cell-mediated antitumor immunity.
    Acta biochimica et biophysica Sinica, 2021, Jan-12, Volume: 53, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Disease Models, Animal; Drug Therapy, Combination; Fluorouracil; Humans; Melanoma; Mice, Inbred C57BL; Neoplasms; NF-kappa B p50 Subunit; Oxaliplatin; Platinum; Stomach Neoplasms; T-Lymphocyte Subsets; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Helper-Inducer

2021
Are taxanes the future for head and neck cancer? Pragmatism in the immunotherapy era.
    The Lancet. Oncology, 2021, Volume: 22, Issue:4

    Topics: Cetuximab; Cisplatin; Docetaxel; Fluorouracil; Head and Neck Neoplasms; Humans; Immunotherapy; Platinum; Taxoids

2021
Next generation platinum salt in nasopharygeal carcinoma.
    The Lancet. Oncology, 2021, Volume: 22, Issue:5

    Topics: Carcinoma; Chemoradiotherapy; Cisplatin; Cyclobutanes; Fluorouracil; Humans; Induction Chemotherapy; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Organoplatinum Compounds; Platinum

2021
Unresolved questions regarding the promise of the TPEx regimen.
    The Lancet. Oncology, 2021, Volume: 22, Issue:6

    Topics: Cetuximab; Cisplatin; Docetaxel; Fluorouracil; Humans; Platinum

2021
Unresolved questions regarding the promise of the TPEx regimen - Authors' reply.
    The Lancet. Oncology, 2021, Volume: 22, Issue:6

    Topics: Cetuximab; Cisplatin; Docetaxel; Fluorouracil; Humans; Platinum

2021
The evolution of hematopoietic cells under cancer therapy.
    Nature communications, 2021, 08-10, Volume: 12, Issue:1

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clonal Evolution; Clone Cells; Cohort Studies; Female; Fluorouracil; Hematopoiesis; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid; Mutagenesis; Mutation; Neoplasms, Second Primary; Platinum; Tumor Suppressor Protein p53

2021
Significance of chemotherapy-free interval and tumor regression grade in patients with recurrent esophageal squamous cell carcinoma receiving chemotherapy with fluorouracil and platinum after esophagectomy following preoperative chemotherapy.
    Esophagus : official journal of the Japan Esophageal Society, 2022, Volume: 19, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Fluorouracil; Humans; Neoplasm Recurrence, Local; Platinum; Retrospective Studies

2022
Treatment and Survival Outcomes Associated With Platinum Plus Low-Dose, Long-term Fluorouracil for Metastatic Nasopharyngeal Carcinoma.
    JAMA network open, 2021, 12-01, Volume: 4, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; China; Cohort Studies; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Platinum; Retrospective Studies; Survival Analysis; Treatment Outcome

2021
Heterotrimetallic Double Cavity Cages: Syntheses and Selective Guest Binding.
    Angewandte Chemie (International ed. in English), 2022, 04-25, Volume: 61, Issue:18

    Topics: Crystallography, X-Ray; Fluorouracil; Magnetic Resonance Spectroscopy; Platinum

2022
Exploratory Study of NPC-0501 Trial: Optimal Cisplatin Dose of Concurrent and Induction/Adjuvant Chemotherapy for Locoregionally Advanced Nasopharyngeal Carcinoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 06-13, Volume: 28, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Cisplatin; Fluorouracil; Humans; Induction Chemotherapy; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Platinum; Radiotherapy, Intensity-Modulated

2022
Comparative analysis of cancer gene mutations using targeted sequencing in matched primary and recurrent gastric cancers after chemotherapy.
    Genes & genomics, 2022, Volume: 44, Issue:11

    Topics: Fluorouracil; Genes, Neoplasm; Humans; Mutation; Platinum; Stomach Neoplasms

2022
Plasma thioredoxin reductase: a potential diagnostic biomarker for gastric cancer.
    Carcinogenesis, 2022, 09-19, Volume: 43, Issue:8

    Topics: Biomarkers, Tumor; Fluorouracil; Humans; Platinum; Stomach Neoplasms; Thioredoxin Reductase 1

2022
The Treatment of Human Colon Xenografts Tumor in Mice with Platinum Nanosphere-5-Fluorouracil-Bovine Albumin.
    Journal of biomedical nanotechnology, 2022, Mar-01, Volume: 18, Issue:3

    Topics: Animals; Cattle; Colon; Fluorouracil; Heterografts; Humans; Mice; Nanospheres; Platinum; Serum Albumin, Bovine

2022
Bladder preservation in older adults with muscle-invasive bladder cancer: A retrospective study with concurrent chemotherapy and twice-daily hypofractionated radiotherapy schedule.
    Journal of geriatric oncology, 2022, Volume: 13, Issue:7

    Topics: Aged; Combined Modality Therapy; Cystectomy; Fluorouracil; Humans; Muscles; Neoplasm Invasiveness; Organ Sparing Treatments; Platinum; Retrospective Studies; Treatment Outcome; Urinary Bladder; Urinary Bladder Neoplasms

2022
Tumor response and survival outcomes of salvage concurrent chemoradiotherapy with three-dimensional conformal radiotherapy and 5-fluorouracil/platinum-based chemotherapy for postoperative locoregional recurrence of esophageal squamous cell carcinoma.
    Esophagus : official journal of the Japan Esophageal Society, 2022, Volume: 19, Issue:4

    Topics: Carcinoma, Squamous Cell; Chemoradiotherapy; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Fluorouracil; Humans; Neoplasm Recurrence, Local; Platinum; Radiotherapy, Conformal; Retrospective Studies

2022
Cost Effectiveness of Adding Pembrolizumab to Platinum and Fluoropyrimidine-Based Chemotherapy as First-Line Treatment for Advanced Esophageal Cancer: A US Healthcare Payer's Perspective.
    PharmacoEconomics, 2022, Volume: 40, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Cost-Benefit Analysis; Delivery of Health Care; Esophageal Neoplasms; Fluorouracil; Humans; Paclitaxel; Platinum; Quality-Adjusted Life Years; Trastuzumab

2022
In search for optimal induction chemotherapy for advanced nasopharyngeal cancer: Standard dosing of Docetaxel, Platinum, and 5-Fluorouracil (TPF) followed by chemoradiation.
    PloS one, 2023, Volume: 18, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Chemoradiotherapy; Cisplatin; Docetaxel; Fluorouracil; Humans; Induction Chemotherapy; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Platinum

2023
Evaluation of long-term data on surface contamination by antineoplastic drugs in pharmacies.
    International archives of occupational and environmental health, 2023, Volume: 96, Issue:5

    Topics: Antineoplastic Agents; Cyclophosphamide; Environmental Monitoring; Equipment Contamination; Fluorouracil; Gemcitabine; Humans; Occupational Exposure; Pharmacies; Platinum

2023
Perioperative therapy with FLOT4 significantly increases survival in patients with gastroesophageal and gastric cancer in a large real-world cohort.
    International journal of cancer, 2023, Aug-01, Volume: 153, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Esophageal Neoplasms; Esophagogastric Junction; Fluorouracil; Humans; Platinum; Prospective Studies; Retrospective Studies; Stomach Neoplasms

2023
First-line cetuximab + platinum-based therapy for recurrent/metastatic head and neck squamous cell carcinoma: A real-world observational study-ENCORE.
    Cancer reports (Hoboken, N.J.), 2023, Volume: 6, Issue:5

    Topics: Carboplatin; Cetuximab; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Neoplasm Recurrence, Local; Platinum; Prospective Studies; Squamous Cell Carcinoma of Head and Neck

2023