fluorouracil has been researched along with phenytoin in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.90) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (34.48) | 29.6817 |
| 2010's | 15 (51.72) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Einhorn, R; Franki, N; Hays, RM; Levine, SD | 1 |
| Scott, JM; Weir, DG | 1 |
| Brodribb, TR; Gilbar, PJ | 1 |
| Findlay, M; Rosemergy, I | 1 |
| Konishi, H; Minouchi, T; Morita, K; Sato, T; Yamaji, A; Yoshimoto, T | 1 |
| Brickell, K; Porter, D; Thompson, P | 1 |
| Altundag, K; Beyazit, Y; Elkiran, ET; Guler, N; Kars, A | 1 |
| Xu, H; Yu, Z | 1 |
| Fukui, E; Kawahara, K; Sakurai, M; Ueda, R; Yamada, R | 1 |
| de Los Ríos la Rosa, F; Privitera, M | 1 |
| Hori, S; Miki, A; Satoh, H; Sawada, Y; Togawa, T; Tsuda, A | 1 |
| Shimizu, T | 1 |
| Ibayashi, Y; Jotoku, H; Takahashi, M; Takasaki, M; Tanaka, H; Watanabe, K | 1 |
| Chai, Z; Li, L; Liu, C; Shen, X; Wang, L; Zhang, X; Zhang, Z | 1 |
| Taguchi, Y; Takashima, S; Tanaka, K | 1 |
| Fukui, E; Hori, S; Ikenishi, M; Kawahara, K; Matsuyama, K; Miki, A; Miyazaki, S; Nakatsuka, E; Ohtori, T; Sakurai, M; Satoh, H; Sawada, Y; Ueda, M; Ueda, R | 1 |
| Keerty, D; Kessler, R; Koverzhenko, V; Peguero, E | 1 |
3 review(s) available for fluorouracil and phenytoin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug-induced megaloblastic change.
Topics: Cyclophosphamide; Cytarabine; DNA; Erythrocytes, Abnormal; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Hydroxyurea; Megaloblasts; Methotrexate; Phenytoin; Pyrimethamine; Ribonucleotides; Thymidine Monophosphate; Thymidylate Synthase; Triamterene; Trimethoprim | 1980 |
[A case of phenytoin intoxication caused by interaction between phenytoin and capecitabine].
Topics: Adult; Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Capecitabine; Deoxycytidine; Drug Interactions; Female; Fluorouracil; Humans; Magnetic Resonance Imaging; Phenytoin | 2015 |
26 other study(ies) available for fluorouracil and phenytoin
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Vasopressin-stimulated movement of drugs and uric acid across the toad urinary bladder.
Topics: Adenine; Animals; Anti-Bacterial Agents; Anura; Butanols; Cell Membrane Permeability; Cyclic AMP; Cyclohexanones; Female; Fluorouracil; Glutethimide; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Phloretin; Stimulation, Chemical; Uric Acid; Urinary Bladder; Vasopressins | 1976 |
Phenytoin and fluorouracil interaction.
Topics: Aged; Anticonvulsants; Antidotes; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Interactions; Fluorouracil; Humans; Leucovorin; Male; Phenytoin; Seizures | 2001 |
Phenytoin toxicity as a result of 5-fluorouracil administration.
Topics: Anticonvulsants; Antimetabolites, Antineoplastic; Drug Interactions; Epilepsy; Female; Fluorouracil; Humans; Middle Aged; Phenytoin; Rectal Neoplasms | 2002 |
Depression of phenytoin metabolic capacity by 5-fluorouracil and doxifluridine in rats.
Topics: Animals; Anticonvulsants; Antimetabolites, Antineoplastic; Cytochrome P-450 Enzyme System; Down-Regulation; Drug Interactions; Floxuridine; Fluorouracil; Male; Microsomes, Liver; Phenytoin; Rats; Rats, Sprague-Dawley | 2003 |
Phenytoin toxicity due to fluoropyrimidines (5FU/capecitabine): three case reports.
Topics: Adenocarcinoma; Administration, Oral; Aged; Anticonvulsants; Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Colonic Neoplasms; Deoxycytidine; Drug Interactions; Epilepsy, Generalized; Female; Fluorouracil; Humans; Male; Middle Aged; Phenytoin | 2003 |
Fluorouracil-induced neurotoxicity presenting with generalized tonic-clonic seizure.
Topics: Adenocarcinoma; Anticonvulsants; Antimetabolites, Antineoplastic; Fluorouracil; Humans; Male; Middle Aged; Neurotoxicity Syndromes; Phenytoin; Seizures; Sigmoid Neoplasms | 2004 |
[Establishment of embryonic stem cell for evaluation of development neurotoxicity and test the validation of embryonic stem cell].
Topics: Animal Testing Alternatives; Animals; BALB 3T3 Cells; Cell Differentiation; Cells, Cultured; Embryonic Stem Cells; Fluorouracil; Mice; Neurons; Penicillin G; Phenytoin; Reproducibility of Results; Toxicity Tests; Tretinoin | 2010 |
[A case of toxicity caused by drug interaction between capecitabine and phenytoin in patient with colorectal cancer].
Topics: Adult; Anticonvulsants; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Interactions; Epilepsy; Female; Fluorouracil; Humans; Phenytoin | 2011 |
Capecitabine-phenytoin interaction is dose dependent with an unexpected time course.
Topics: Aged; Anticonvulsants; Antineoplastic Agents; Breast Neoplasms; Capecitabine; Deoxycytidine; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Female; Fluorouracil; Humans; Phenytoin | 2011 |
Sequential interaction of phenytoin and phenobarbital with fluorouracil.
Topics: Drug Interactions; Fluorouracil; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 2012 |
[Ataxia].
Topics: Anticonvulsants; Antimetabolites, Antineoplastic; Antipsychotic Agents; Ataxia; Fluorouracil; Humans; Lithium; Phenytoin | 2012 |
[Effect of capecitabine therapy on the blood levels of antiepileptic drugs - report of two cases].
Topics: Anticonvulsants; Antimetabolites, Antineoplastic; Brain Neoplasms; Breast Neoplasms; Capecitabine; Deoxycytidine; Drug Interactions; Female; Fluorouracil; Humans; Middle Aged; Phenytoin; Seizures; Valproic Acid | 2014 |
A toxicology study to evaluate the embryotoxicity of metformin compared with the hypoglycemic drugs, the anticancer drug, the anti-epileptic drug, the antibiotic, and the cyclo-oxygenase (COX)-2 inhibitor.
Topics: 3T3 Cells; Animals; Anti-Bacterial Agents; Anticonvulsants; Antineoplastic Agents; Cell Differentiation; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Embryonic Stem Cells; Fibroblasts; Fluorouracil; Gene Expression Regulation, Developmental; Hypoglycemic Agents; Metformin; Mice; Penicillins; Phenytoin; Risk Assessment; Rosiglitazone; Sulfonamides; Sulfonylurea Compounds; Thiazolidinediones | 2015 |
Pharmacokinetic model analysis of interaction between phenytoin and capecitabine.
Topics: Administration, Oral; Anticonvulsants; Antimetabolites, Antineoplastic; Capecitabine; Cytochrome P-450 CYP2C9; Drug Interactions; Fluorouracil; Humans; Models, Biological; Nonlinear Dynamics; Phenytoin | 2016 |
Dyskinesia during concomitant usage of phenytoin and capecitabine.
Topics: Anticonvulsants; Capecitabine; Dyskinesias; Fluorouracil; Humans; Phenytoin | 2021 |