fluorouracil has been researched along with oligonucleotides in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (45.00) | 29.6817 |
| 2010's | 9 (45.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goh, SH; Léjohn, HB | 1 |
| Catlin, JC; Guschlbauer, W | 1 |
| Dorr, FA; Geary, RS; Holmlund, JT; Kindler, HL; Kunkel, K; Mani, S; Ratain, MJ; Rudin, CM | 1 |
| Ashida, Y; Azuma, M; Harada, K; Kawaguchi, S; Motegi, K; Sato, M; Takashima, R; Tamatani, T | 1 |
| Liu, WM; Propper, DJ; Scott, KA; Shahin, S | 1 |
| Bi, F; Fan, D; Liu, N; Pan, Y; Shi, Y; Sun, L; Xue, Y; Yao, X; Zheng, Y | 1 |
| Cabrera, BL; Carethers, JM; Hess, MT; Kolodner, RD; Tajima, A | 1 |
| Guang, Y; Ruan, YB; Sheng, Z; Wang, XS; Yang, ML | 1 |
| Beck, S; Bourquin, C; Endres, S; Hartmann, G; Schreiber, S | 1 |
| Anderson, K; Booser, D; Buzdar, AU; Dempsey, PJ; Gómez, HL; Hess, KR; Hortobagyi, GN; Ibrahim, N; Mejia, JA; Pusztai, L; Ross, JS; Rouzier, R; Sneige, N; Symmans, WF; Theriault, RL; Valero, V; Vidaurre, T | 1 |
| Ebert, MO; Konrat, R; Kreutz, C; Micura, R; Puffer, B; Rieder, U | 1 |
| Fukushima, M; Suzuki, N | 1 |
| Cabrera, BL; Carethers, JM; Iwaizumi, M; Tajima, A; Tseng-Rogenski, S | 1 |
| Andreeva, TV; Artamonov, AV; Bekarev, AA; Dygai, AM; Ermakova, NN; Goldberg, VE; Khmelevskaya, ES; Madonov, PG; Pershina, OV; Skurikhin, EG; Vereschagin, EI | 1 |
| Brümmendorf, TH; Delord, JP; Forssmann, U; Goddemeier, T; Kaminsky, MC; Keller, U; Machiels, JP | 1 |
| Bray, C; Celik, I; Chang, SC; Denne, J; Green, G; Harbison, C; Horak, C; Khambata-Ford, S; Van Cutsem, E; Zhao, L | 1 |
| Afonso, R; Angeles, C; Campos, JM; García-Alfonso, P; Grande, E; Jorge, M; Martínez, V; Montagut, C; Polo, E; Reina, JJ | 1 |
| Fujimoto, K; Furusawa, M; Sakamoto, T; Shigeno, A; Takematsu, YK | 1 |
| Chan, E; de La Bourdonnaye, G; Heiskala, M; Hwang, J; Kwak, EL; Mita, M | 1 |
| Burris, HA; Chen, L; Goldstein, D; Hsu, CP; Hurwitz, H; Kotasek, D; Schwartzberg, LS; Stephenson, J; Tebbutt, N; Warner, DJ | 1 |
1 review(s) available for fluorouracil and oligonucleotides
| Article | Year |
|---|---|
The role of antiangiogenic agents in the treatment of patients with advanced colorectal cancer according to K-RAS status.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Axitinib; Bevacizumab; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; ErbB Receptors; Fluorouracil; Genes, ras; Humans; Imidazoles; Indazoles; Indoles; Irinotecan; Niacinamide; Oligonucleotides; Organoplatinum Compounds; Oxaliplatin; Pharmacogenetics; Phenylurea Compounds; Prognosis; Protein-Tyrosine Kinases; Pyridines; Pyrroles; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Signal Transduction; Sorafenib; Sunitinib; Vascular Endothelial Growth Factor A | 2014 |
4 trial(s) available for fluorouracil and oligonucleotides
| Article | Year |
|---|---|
Phase I clinical and pharmacokinetic study of protein kinase C-alpha antisense oligonucleotide ISIS 3521 administered in combination with 5-fluorouracil and leucovorin in patients with advanced cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Diarrhea; DNA, Antisense; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fatigue; Female; Fluorouracil; Humans; Isoenzymes; Leucovorin; Male; Middle Aged; Nausea; Neoplasms; Neutropenia; Oligonucleotides; Protein Kinase C; Protein Kinase C-alpha; Thionucleotides; Thrombocytopenia; Treatment Outcome; Vomiting | 2002 |
Phase Ib trial of the Toll-like receptor 9 agonist IMO-2055 in combination with 5-fluorouracil, cisplatin, and cetuximab as first-line palliative treatment in patients with recurrent/metastatic squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Oligonucleotides; Squamous Cell Carcinoma of Head and Neck; Toll-Like Receptor 9; Treatment Outcome | 2013 |
Open-label phase 1b study of FOLFIRI plus cetuximab plus IMO-2055 in patients with colorectal cancer who have progressed following chemotherapy for advanced or metastatic disease.
Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Oligonucleotides; Toll-Like Receptor 9 | 2015 |
Motesanib with or without panitumumab plus FOLFIRI or FOLFOX for the treatment of metastatic colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Indoles; Leucovorin; Male; Middle Aged; Niacinamide; Oligonucleotides; Organoplatinum Compounds; Panitumumab; Young Adult | 2015 |
15 other study(ies) available for fluorouracil and oligonucleotides
| Article | Year |
|---|---|
Genetical and biochemical evidence that a novel dinucleoside polyphosphate coordinates salvage and de novo nucleotide biosynthetic pathways in mammalian cells.
Topics: Azaserine; Cell Line; Fluorouracil; Genes; Glutamine; Guanosine Triphosphate; Methotrexate; Mutation; Oligonucleotides; Oligoribonucleotides; Ribonucleotides | 1977 |
Oligonucleotide conformations. III. Comparative optical and thermodynamic studies of uridylyl-3'-5'-nucleosides containing ribose, deoxyribose, or 2'-deoxy-2'-fluororibose in the uridine moiety.
Topics: Circular Dichroism; Deoxyribonucleosides; Fluorouracil; Oligonucleotides; Ribonucleosides; Structure-Activity Relationship; Thermodynamics; Uridine | 1975 |
Enhanced radiosensitization and chemosensitization in NF-kappaB-suppressed human oral cancer cells via the inhibition of gamma-irradiation- and 5-FU-induced production of IL-6 and IL-8.
Topics: Animals; Annexin A5; Antimetabolites, Antineoplastic; Apoptosis; Blotting, Western; Carcinoma; Cell Division; Cell Nucleus; Cell Separation; Culture Media, Conditioned; Cytosol; DNA, Complementary; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluorouracil; Gamma Rays; Genetic Vectors; Humans; I-kappa B Proteins; Immunohistochemistry; Interleukin-6; Interleukin-8; Luciferases; Matrix Metalloproteinase 9; Mice; Mice, Nude; Mouth Neoplasms; Mutation; Neovascularization, Pathologic; NF-kappa B; NF-KappaB Inhibitor alpha; Oligonucleotides; Time Factors; Transfection; Vascular Endothelial Growth Factor A | 2004 |
The in vitro effects of CRE-decoy oligonucleotides in combination with conventional chemotherapy in colorectal cancer cell lines.
Topics: Base Sequence; Camptothecin; Cell Division; Cell Line, Tumor; Colorectal Neoplasms; Cyclin-Dependent Kinases; Etoposide; Flow Cytometry; Fluorouracil; Humans; In Vitro Techniques; Irinotecan; Oligonucleotides | 2004 |
Reversal of the malignant phenotype of gastric cancer cells by inhibition of RhoA expression and activity.
Topics: Agar; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Blotting, Western; Cell Cycle; Cell Differentiation; Cell Line, Transformed; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; DNA; Dose-Response Relationship, Drug; Doxorubicin; Epithelial Cells; Flow Cytometry; Fluorouracil; Genes, Dominant; Humans; Immunohistochemistry; Mice; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Oligonucleotides; Phenotype; rhoA GTP-Binding Protein; RNA, Small Interfering; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Wound Healing | 2004 |
The mismatch repair complex hMutS alpha recognizes 5-fluorouracil-modified DNA: implications for chemosensitivity and resistance.
Topics: Adenosine Triphosphatases; Antimetabolites, Antineoplastic; Bacterial Proteins; Base Pair Mismatch; DNA Adducts; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Drug Resistance, Neoplasm; Fluorouracil; Humans; Microsatellite Repeats; MutS DNA Mismatch-Binding Protein; Oligonucleotides | 2004 |
CpG oligodeoxynucleotides inhibit tumor growth and reverse the immunosuppression caused by the therapy with 5-fluorouracil in murine hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Combined Modality Therapy; CpG Islands; Fluorouracil; Genetic Therapy; Immunosuppressive Agents; Interferon-gamma; Interleukin-12; Killer Cells, Natural; Liver Neoplasms; Mice; Mice, Inbred BALB C; Oligonucleotides; Spleen | 2005 |
Immunotherapy with dendritic cells and CpG oligonucleotides can be combined with chemotherapy without loss of efficacy in a mouse model of colon cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; CpG Islands; Dendritic Cells; Disease Models, Animal; Female; Fluorouracil; Humans; Immunotherapy; Irinotecan; Mice; Mice, Inbred BALB C; Oligonucleotides | 2006 |
Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Microarray Analysis; Middle Aged; Neoplasm Staging; Oligonucleotides; Paclitaxel; Predictive Value of Tests; Reproducibility of Results; ROC Curve; Sensitivity and Specificity | 2006 |
5-Fluoro pyrimidines: labels to probe DNA and RNA secondary structures by 1D 19F NMR spectroscopy.
Topics: Aptamers, Nucleotide; Cytidine; DNA; Flucytosine; Fluorouracil; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleic Acid Probes; Oligonucleotides; Organophosphorus Compounds; RNA; Thermodynamics | 2009 |
Simple and rapid enzymatic method for the synthesis of single-strand oligonucleotides containing trifluorothymidine.
Topics: Autoradiography; Bromodeoxyuridine; Denaturing Gradient Gel Electrophoresis; DNA Damage; DNA Ligases; DNA Primers; DNA-Directed DNA Polymerase; Fluorouracil; Oligonucleotides; Thymine DNA Glycosylase; Trifluridine | 2010 |
Both hMutSα and hMutSß DNA mismatch repair complexes participate in 5-fluorouracil cytotoxicity.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Baculoviridae; Cell Line, Tumor; Colonic Neoplasms; Cross-Linking Reagents; DNA Mismatch Repair; DNA-Binding Proteins; Fluorouracil; Humans; Microsatellite Repeats; Oligonucleotides; Recombinant Proteins; Surface Plasmon Resonance; Tetrazolium Salts; Thiazoles; Treatment Outcome | 2011 |
Effects and mechanisms of hemopoiesis-stimulating activity of immobilized oligonucleotides under conditions of cytostatic myelosuppression.
Topics: Administration, Oral; Animals; Blood Platelets; Bone Marrow; Cell Count; Cyclophosphamide; Cytostatic Agents; Erythropoiesis; Fluorouracil; Granulocytes; Hematinics; Injections, Intraperitoneal; Leukocytes, Mononuclear; Mice; Mice, Inbred CBA; Myelopoiesis; Oligonucleotides | 2012 |
Comparison of KRAS genotype: therascreen assay vs. LNA-mediated qPCR clamping assay.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; DNA, Neoplasm; Female; Fluorouracil; Follow-Up Studies; Genotype; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Mutation; Neoplasm Staging; Oligonucleotides; Polymerase Chain Reaction; Prognosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Retrospective Studies; Survival Rate; Young Adult | 2013 |
Short oligonucleotide prodrug having 5-fluoro and 5-iodouracil inhibits the proliferation of cancer cells in a photo-responsive manner.
Topics: Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fluorouracil; HeLa Cells; Humans; Molecular Structure; Oligonucleotides; Photochemical Processes; Prodrugs; Structure-Activity Relationship; Uracil | 2014 |