Compounds > fluorouracil

fluorouracil and nutlin-3a

fluorouracil has been researched along with nutlin-3a in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Abolmaali, ND; Tokalov, SV1
Abei, M; Endo, S; Fukuda, K; Hirai, S; Hyodo, I; Moriwaki, T; Nakagawa, I; Suzuki, H; Yamato, K1
Bisio, A; Ciribilli, Y; De Sanctis, V; Inga, A; Lion, M; Menendez, D; Resnick, MA; Tebaldi, T1
Iimori, M; Kadomatsu, K; Kitao, H; Kiyonari, S; Maehara, Y; Matsuoka, K; Miura, D; Morikawa-Ichinose, T; Morita, M; Niimi, S; Oki, E; Saeki, H; Tokunaga, E; Watanabe, S1
Abraham, BJ; Amat, R; Fisher, RP; Gray, NS; Kalan, S; Kwiatkowski, N; Larochelle, S; Liang, Y; Olson, CM; Schachter, MM; Young, RA; Zhang, T1
Dowell, RD; Gruca, M; Jones, T; Levandowski, CB; Ramamoorthy, S; Taatjes, DJ1

Other Studies

6 other study(ies) available for fluorouracil and nutlin-3a

ArticleYear
Protection of p53 wild type cells from taxol by nutlin-3 in the combined lung cancer treatment.
    BMC cancer, 2010, Feb-23, Volume: 10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Cell Line, Tumor; Drug Screening Assays, Antitumor; Flow Cytometry; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Lung Neoplasms; Models, Genetic; Mutation; Piperazines; Purines; Roscovitine; Tumor Suppressor Protein p53

2010
Potent in vitro and in vivo antitumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cells.
    Cancer science, 2011, Volume: 102, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Female; Fluorouracil; Gene Dosage; Humans; Imidazoles; Mice; Mice, Inbred BALB C; Nuclear Proteins; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Stomach Neoplasms; Tumor Suppressor Protein p53

2011
Interaction between p53 and estradiol pathways in transcriptional responses to chemotherapeutics.
    Cell cycle (Georgetown, Tex.), 2013, Apr-15, Volume: 12, Issue:8

    Topics: Blotting, Western; Doxorubicin; Estradiol; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation; Humans; Imidazoles; MCF-7 Cells; Microarray Analysis; Piperazines; Real-Time Polymerase Chain Reaction; Time Factors; Transcription, Genetic; Tumor Suppressor Protein p53

2013
The 1,2-Diaminocyclohexane Carrier Ligand in Oxaliplatin Induces p53-Dependent Transcriptional Repression of Factors Involved in Thymidylate Biosynthesis.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:10

    Topics: Biosynthetic Pathways; DNA Replication; Down-Regulation; Drug Synergism; E2F1 Transcription Factor; E2F3 Transcription Factor; Fluorouracil; Gene Expression Regulation, Neoplastic; Gene Silencing; HCT116 Cells; Humans; Imidazoles; MicroRNAs; Organoplatinum Compounds; Oxaliplatin; Piperazines; Pyrophosphatases; Sp1 Transcription Factor; Thymidine Monophosphate; Transcription, Genetic; Tumor Suppressor Protein p53

2015
Activation of the p53 Transcriptional Program Sensitizes Cancer Cells to Cdk7 Inhibitors.
    Cell reports, 2017, Oct-10, Volume: 21, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Imidazoles; Phenylenediamines; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Transcriptional Activation; Tumor Suppressor Protein p53

2017
The Δ40p53 isoform inhibits p53-dependent eRNA transcription and enables regulation by signal-specific transcription factors during p53 activation.
    PLoS biology, 2021, Volume: 19, Issue:8

    Topics: Cell Line; Fluorouracil; Genes, p53; Humans; Imidazoles; Piperazines; Protein Isoforms; Protein Structure, Quaternary; Transcription Factors; Transcription, Genetic; Transcriptome; Tumor Suppressor Protein p53

2021