fluorouracil and nitroglycerin

fluorouracil has been researched along with nitroglycerin in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.76)18.2507
2000's7 (41.18)29.6817
2010's8 (47.06)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gotsman, MS; Gurewich, J; Rozenman, Y1
Chokshi, S; Fingert, HJ; Isner, JM; Mosseri, M; Varticovski, L1
Aoki, T; Hosoya, Y; Kobayashi, N; Nagai, H; Nihei, Y; Saito, S; Saito, Y; Shoji, M; Yokoyama, T1
Cannita, K; Cianci, G; Di Rocco, ZC; Ficorella, C; Lanfiuti Baldi, P; Morelli, MF; Morese, R; Porzio, G; Ricevuto, E1
Jensen, SA; Sørensen, JB1
Marek, A; Schmittel, A; Schultheiss, HP; Spencker, S; Westermann, D; Witzenbichler, B1
Darodes, N; Genet, D; Labourey, JL; Le Brun-Ly, V; Martin, J; Tubiana-Mathieu, N; Venat-Bouvet, L1
Baeksgaard, L; Jensen, SA; Petersen, LN; Reiter, L; Sørensen, JB1
Han, JY; Kim, HT; Kim, HY; Lee, JS; Nam, BH; Yoon, SJ1
Cho, WH; Choi, SK; Kim, SB; Kim, SM; Kwak, CH; Lee, B; Sir, JJ1
Dowell, JE; Hittson, WJ; Huerta, S; Illum, H; Meyer, J; Torrisi, JR; Wang, DH1
Ben-Yakov, M; Brady, WJ; Dubbs, SB; Mattu, A1
Asnani, A; Faridi, KF; Mukhopadhyay, A; Osborn, EA; Phillips, CT; Yang, JX; York, M1

Reviews

2 review(s) available for fluorouracil and nitroglycerin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Angina attack caused by 5-fluorouracil infusion--report of a case and review of the literature].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:10

    Topics: Angina Pectoris; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Isosorbide Dinitrate; Liver Neoplasms; Middle Aged; Nitroglycerin; Sigmoid Neoplasms

2002

Trials

2 trial(s) available for fluorouracil and nitroglycerin

ArticleYear
A randomized phase II study of irinotecan plus cisplatin versus irinotecan plus capecitabine with or without isosorbide-5-mononitrate in advanced non-small-cell lung cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Carcinoma, Non-Small-Cell Lung; Cisplatin; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Irinotecan; Isosorbide Dinitrate; Lung Neoplasms; Male; Middle Aged; Nitroglycerin; Treatment Outcome

2012
Phase I dose escalation trial of nitroglycerin in addition to 5-fluorouracil and radiation therapy for neoadjuvant treatment of operable rectal cancer.
    Surgery, 2015, Volume: 158, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Drug Administration Schedule; Feasibility Studies; Fluorouracil; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoadjuvant Therapy; Nitroglycerin; Rectal Neoplasms; Treatment Outcome

2015

Other Studies

13 other study(ies) available for fluorouracil and nitroglycerin

ArticleYear
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Myocardial ischemia induced by topical use of 5-fluorouracil.
    International journal of cardiology, 1995, Volume: 49, Issue:3

    Topics: Administration, Topical; Aged; Aged, 80 and over; Angina Pectoris; Carcinoma, Basal Cell; Drug Therapy, Combination; Facial Neoplasms; Female; Fluorouracil; Humans; Isosorbide; Myocardial Ischemia; Nitroglycerin

1995
In vitro evidence that myocardial ischemia resulting from 5-fluorouracil chemotherapy is due to protein kinase C-mediated vasoconstriction of vascular smooth muscle.
    Cancer research, 1993, Jul-01, Volume: 53, Issue:13

    Topics: Animals; Antineoplastic Agents; Calcium Channels; Drug Interactions; Endothelium, Vascular; Fluorouracil; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocardial Ischemia; Nitroglycerin; Phosphatidylinositols; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Rabbits; Receptors, Adrenergic; Structure-Activity Relationship; Time Factors; Vasoconstriction; Vasoconstrictor Agents

1993
Prophylactic options in patients with 5-fluorouracil-associated cardiotoxicity.
    British journal of cancer, 2003, May-19, Volume: 88, Issue:10

    Topics: Aged; Angina Pectoris; Antimetabolites, Antineoplastic; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Nitroglycerin; Vasodilator Agents

2003
Risk factors and prevention of cardiotoxicity induced by 5-fluorouracil or capecitabine.
    Cancer chemotherapy and pharmacology, 2006, Volume: 58, Issue:4

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Atherosclerosis; Capecitabine; Comorbidity; Deoxycytidine; Female; Fluorouracil; Gastrointestinal Neoplasms; Heart Diseases; Humans; Kidney Diseases; Male; Middle Aged; Nitroglycerin; Retrospective Studies; Risk Factors; Vasodilator Agents

2006
[Angina pectoris and ST-elevation after chemotherapy with 5-fluorouracil].
    Der Internist, 2007, Volume: 48, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Angina Pectoris; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Coronary Angiography; Coronary Vasospasm; Diagnosis, Differential; Electrocardiography; Fluorouracil; Humans; Infusions, Intravenous; Male; Neoplasms, Unknown Primary; Nitroglycerin; Oropharyngeal Neoplasms; Radiotherapy, Adjuvant; Vasodilator Agents

2007
Cardiac toxicity with capecitabine, vinorelbine and trastuzumab therapy: case report and review of fluoropyrimidine-related cardiotoxicity.
    Oncology, 2009, Volume: 76, Issue:5

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Chest Pain; Deoxycytidine; Electrocardiography; Female; Fluorouracil; Humans; Myocardial Ischemia; Nitroglycerin; Prognosis; Trastuzumab; Treatment Outcome; Vinblastine; Vinorelbine

2009
[Cardiotoxicity induced by 5-fluorouracil or capecitabine].
    Ugeskrift for laeger, 2010, Jan-04, Volume: 172, Issue:1

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Heart; Heart Diseases; Humans; Isosorbide Dinitrate; Nitroglycerin; Prodrugs; Risk Factors; Vasodilator Agents

2010
A case of severe coronary spasm associated with 5-fluorouracil chemotherapy.
    The Korean journal of internal medicine, 2012, Volume: 27, Issue:3

    Topics: Aged, 80 and over; Angina Pectoris; Antineoplastic Combined Chemotherapy Protocols; Calcium Channel Blockers; Colonic Neoplasms; Coronary Angiography; Coronary Vasospasm; Drug-Eluting Stents; Electrocardiography; Fluorouracil; Humans; Leucovorin; Male; Nifedipine; Nitroglycerin; Organoplatinum Compounds; Percutaneous Coronary Intervention; Recurrence; Severity of Illness Index; Treatment Outcome; Vasodilator Agents

2012
Prinzmetal angina (Coronary vasospasm) associated with 5-fluorouracil chemotherapy.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:7

    Topics: Administration, Sublingual; Antineoplastic Combined Chemotherapy Protocols; Chest Pain; Coronary Angiography; Coronary Vasospasm; Electrocardiography; Fluorouracil; Humans; Male; Middle Aged; Nitroglycerin; Rectal Neoplasms; Treatment Outcome; Vasodilator Agents

2017
Chest Pain During Chemotherapy: A Case of Severe Myocardial Bridging.
    The Journal of invasive cardiology, 2018, Volume: 30, Issue:7

    Topics: Antimetabolites, Antineoplastic; Coronary Angiography; Coronary Vasospasm; Drug Substitution; Electrocardiography; Female; Fluorouracil; Humans; Middle Aged; Myocardial Bridging; Nitroglycerin; Pancreatic Neoplasms; Treatment Outcome; Vasodilator Agents

2018