fluorouracil has been researched along with nadp in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (60.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gilev, AP; Khagi, KhB; Meĭren, DV; Sniedze, TN; Urbanovich, EL | 1 |
| Akiyoshi, H; Fujii, S; Minato, Y; Okuda, H; Toide, H | 1 |
| Theiss-Seuberling, HB | 1 |
| Willén, R | 1 |
| Balnave, D; Pearce, J | 1 |
| Staehelin, M | 1 |
| Floch, MH; Kaufmann, HJ; Spiro, HM | 2 |
| Neef, V; Wilmanns, W | 1 |
| Farquhar, D; Kuttesch, NJ; Wilkerson, MG; Winkler, T | 1 |
| Ogura, K; Okuda, H; Watabe, T | 1 |
| Diasio, RB; Johnson, MR; Mattison, LK | 1 |
| Nishiyama, T; Ogura, K; Watabe, T | 1 |
| BRESNICK, E; YANG, HY | 1 |
| EVANS, WR; LYMAN, H; SMILLIE, RM | 1 |
| Clynes, M; Martinez, VG; O'Connor, R; Stratford, IJ; Williams, KJ | 1 |
| Calvani, M; Caselli, A; Chiarugi, P; Cirri, P; Denise, C; Giannoni, E; Kazmi, SM; Kopetz, S; Landriscina, M; Paoli, P; Pettazzoni, P; Pia, MM; Sacco, E; Taddei, ML; Vanoni, M | 1 |
| Chen, J; Huang, K; Qiu, J; Wu, M; Xia, C; Zhang, Y; Zhu, H | 1 |
| Hong, C; Li, X; Zheng, J | 1 |
| Cao, J; Chen, D; Sun, X; Zhang, X | 1 |
2 review(s) available for fluorouracil and nadp
| Article | Year |
|---|---|
[Lethal drug interactions of the new antiviral, sorivudine, with anticancer prodrugs of 5-fluorouracil].
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antiviral Agents; Arabinofuranosyluracil; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Fluorouracil; Humans; NADP; Oxidoreductases; Prodrugs; Rats | 1997 |
[Molecular toxicological mechanism of the lethal interactions of the new antiviral drug, sorivudine, with 5-fluorouracil prodrugs and genetic deficiency of dihydropyrimidine dehydrogenase].
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Drug Therapy, Combination; Fluorouracil; Humans; NADP; Oxidoreductases; Prodrugs; Rats | 2002 |
18 other study(ies) available for fluorouracil and nadp
| Article | Year |
|---|---|
[Participation of non-specific rat liver microsome oxidases in destruction of Nl-furanidylpyrimidines].
Topics: Animals; Biotransformation; Fluorouracil; Male; Microsomes, Liver; NADP; Proadifen; Rats; Tegafur | 1977 |
Comparative studies on the metabolism of 2-(tetrahydrofuryl)-5-fluorouracil and 5-fluorouracil.
Topics: Alanine; Animals; DNA, Neoplasm; Fluorouracil; In Vitro Techniques; Male; Mice; Microsomes, Liver; NADP; Neoplasms, Experimental; Nucleic Acid Precursors; Rats; Tegafur; Tissue Distribution | 1977 |
[Effect of x-rays and inhibitors of protein synthesis on the synthesis of chlorophyll and NADP-linked glyceraldehyde 3-phosphate dehydrogenase in greening Euglena gracilis].
Topics: Chloramphenicol; Chlorophyll; Chlorophyta; Dactinomycin; Darkness; Euglena gracilis; Fluorouracil; Glyceraldehyde-3-Phosphate Dehydrogenases; Light; NADP; Photosynthesis; Plant Proteins; Protein Biosynthesis; Radiation Effects; Rifampin; Time Factors; Transcription, Genetic | 1973 |
Fluorouracil effect on cytochrome c reductase activity of rat liver cell endoplasmic reticulum following partial hepatectomy.
Topics: Animals; Cytochrome Reductases; Endoplasmic Reticulum; Fluorouracil; Hepatectomy; Liver; Male; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADP; Rats; Stimulation, Chemical | 1973 |
Induction by gonadal hormones of hepatic lipogenic enzyme activity in immature pullets.
Topics: Analysis of Variance; Animals; ATP Citrate (pro-S)-Lyase; Body Weight; Chickens; Cycloheximide; DNA; Enzyme Induction; Estradiol; Female; Fluorouracil; Injections, Intramuscular; Liver; Malate Dehydrogenase; NADP; Organ Size; Progesterone; RNA; Testosterone | 1974 |
Action of puromycin and 5-fluorouracil on the adrenal responsiveness to corticotrophin.
Topics: Adenine Nucleotides; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Fluorouracil; Glucosyltransferases; In Vitro Techniques; NADP; Phosphates; Protein Biosynthesis; Puromycin; Rats; RNA | 1965 |
Intestinal epithelial enzyme abnormalities induced by 5-fluorouracil: translocation of NADPH2-dehydrogenase.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Autopsy; Biopsy; Colitis, Ulcerative; Colon; Esterases; Fluorouracil; Histocytochemistry; Humans; Intestinal Mucosa; Intestine, Small; Jejunum; Mice; NADP; Oxidoreductases | 1967 |
Prevention of 5-FU induced NADPH-D translocation in colonic epithelium by antibiotics and the effect on the intestinal bacterial flora.
Topics: Animals; Clostridium; Colon; Epithelium; Escherichia; Fluorouracil; Histocytochemistry; Lactobacillus; Mice; NADP; Neomycin; Oxidoreductases; Penicillins; Streptococcus | 1967 |
[Determination, properties and inhibition of thymidilate synthetase in immature myeloid blood and bone marrow cells].
Topics: Bone Marrow; Bone Marrow Cells; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Hydrogen-Ion Concentration; Ions; Leukocytes; Magnesium; Mercaptoethanol; Methyltransferases; NADP; Transferases; Tritium; Uracil Nucleotides | 1971 |
Synthesis and biological evaluation of neutral derivatives of 5-fluoro-2'-deoxyuridine 5'-phosphate.
Topics: 5'-Nucleotidase; Alkaline Phosphatase; Animals; Arabinonucleotides; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Fluorouracil; Leukemia P388; Mice; Microsomes, Liver; NADP; Nucleotidases; Phosphoric Diester Hydrolases | 1983 |
A comparative analysis of translated dihydropyrimidine dehydrogenase cDNA; conservation of functional domains and relevance to genetic polymorphisms.
Topics: Amino Acid Sequence; Animals; Binding Sites; Caenorhabditis elegans; Cattle; Cloning, Molecular; Dihydrouracil Dehydrogenase (NADP); DNA, Complementary; Drosophila; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Fluorouracil; Humans; Mice; Molecular Sequence Data; NADP; Oxidoreductases; Polymorphism, Genetic; Rats; Sequence Homology, Amino Acid; Swine; Uracil | 2002 |
THE INFLUENCE OF PHENOBARBITAL ADMINISTRATION UPON THE "SOLUBLE" NADP-REQUIRING ENZYMES IN LIVER.
Topics: Aminopyrine; Benzopyrenes; Citrates; Diphenhydramine; Ethionine; Fluorouracil; Gluconates; Hexosephosphates; Isocitrate Dehydrogenase; Liver; Mercaptopurine; Methylcholanthrene; NADP; Oxidoreductases; Pharmacology; Phenobarbital; Phenylalanine; Rats; Research; Uracil | 1964 |
METABOLIC EVENTS DURING THE FORMATION OF A PHOTOSYNTHETIC FROM A NONPHOTOSYNTHETIC CELL.
Topics: Arsenicals; Azides; Beryllium; Chloramphenicol; Chlorophyll; Chloroplasts; Cyanides; Dihydrolipoamide Dehydrogenase; Dinitrophenols; Euglena; Fluorides; Fluorouracil; Fructose-Bisphosphate Aldolase; Malonates; NADP; Nucleoproteins; Pharmacology; Photosynthesis; Proteins; Research; Ribonucleases; Ribosomes; RNA | 1964 |
Overexpression of cytochrome P450 NADPH reductase sensitises MDA 231 breast carcinoma cells to 5-fluorouracil: possible mechanisms involved.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Female; Fluorouracil; Glutathione; Humans; Microsomes; Mitomycin; NADP; NADPH-Ferrihemoprotein Reductase; Reactive Oxygen Species; Transfection; Vincristine | 2008 |
5-fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Biomarkers, Tumor; Carrier Proteins; Cell Proliferation; Colonic Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Female; Fluorouracil; HT29 Cells; Humans; Membrane Proteins; Mice, Nude; Mitochondria; NADP; Neoplastic Stem Cells; Oxidation-Reduction; Oxidative Phosphorylation; Phenotype; Pyruvate Kinase; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
IDH1 R132H Mutation Enhances Cell Migration by Activating AKT-mTOR Signaling Pathway, but Sensitizes Cells to 5-FU Treatment as NADPH and GSH Are Reduced.
Topics: Agammaglobulinaemia Tyrosine Kinase; Blotting, Western; Cell Line; Cell Movement; Cell Proliferation; Fluorouracil; Glioma; Glutathione; Humans; Isocitrate Dehydrogenase; Mutation; NADP; Protein-Tyrosine Kinases; Signal Transduction; TOR Serine-Threonine Kinases | 2017 |
Inhibition of GOT1 sensitizes colorectal cancer cells to 5-fluorouracil.
Topics: Antimetabolites, Antineoplastic; Aspartate Aminotransferase, Cytoplasmic; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Fluorouracil; HT29 Cells; Humans; Lentivirus; NADP; Oxidative Stress; Reactive Oxygen Species; RNA, Small Interfering; Transfection | 2017 |
6PGD Upregulation is Associated with Chemo- and Immuno-Resistance of Renal Cell Carcinoma via AMPK Signaling-Dependent NADPH-Mediated Metabolic Reprograming.
Topics: AMP-Activated Protein Kinases; Carcinoma, Renal Cell; Cell Line; Cell Line, Tumor; Cellular Reprogramming; Drug Resistance, Neoplasm; Enzyme Activation; Fluorouracil; Gene Knockdown Techniques; Humans; Immunotherapy; Interferon-alpha; Kidney; Kidney Neoplasms; NADP; Phosphogluconate Dehydrogenase; RNA, Small Interfering; Signal Transduction; Up-Regulation | 2020 |