fluorouracil and nadp

fluorouracil has been researched along with nadp in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199012 (60.00)18.7374
1990's1 (5.00)18.2507
2000's3 (15.00)29.6817
2010's3 (15.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Gilev, AP; Khagi, KhB; Meĭren, DV; Sniedze, TN; Urbanovich, EL1
Akiyoshi, H; Fujii, S; Minato, Y; Okuda, H; Toide, H1
Theiss-Seuberling, HB1
Willén, R1
Balnave, D; Pearce, J1
Staehelin, M1
Floch, MH; Kaufmann, HJ; Spiro, HM2
Neef, V; Wilmanns, W1
Farquhar, D; Kuttesch, NJ; Wilkerson, MG; Winkler, T1
Ogura, K; Okuda, H; Watabe, T1
Diasio, RB; Johnson, MR; Mattison, LK1
Nishiyama, T; Ogura, K; Watabe, T1
BRESNICK, E; YANG, HY1
EVANS, WR; LYMAN, H; SMILLIE, RM1
Clynes, M; Martinez, VG; O'Connor, R; Stratford, IJ; Williams, KJ1
Calvani, M; Caselli, A; Chiarugi, P; Cirri, P; Denise, C; Giannoni, E; Kazmi, SM; Kopetz, S; Landriscina, M; Paoli, P; Pettazzoni, P; Pia, MM; Sacco, E; Taddei, ML; Vanoni, M1
Chen, J; Huang, K; Qiu, J; Wu, M; Xia, C; Zhang, Y; Zhu, H1
Hong, C; Li, X; Zheng, J1
Cao, J; Chen, D; Sun, X; Zhang, X1

Reviews

2 review(s) available for fluorouracil and nadp

ArticleYear
[Lethal drug interactions of the new antiviral, sorivudine, with anticancer prodrugs of 5-fluorouracil].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1997, Volume: 117, Issue:10-11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antiviral Agents; Arabinofuranosyluracil; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Fluorouracil; Humans; NADP; Oxidoreductases; Prodrugs; Rats

1997
[Molecular toxicological mechanism of the lethal interactions of the new antiviral drug, sorivudine, with 5-fluorouracil prodrugs and genetic deficiency of dihydropyrimidine dehydrogenase].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2002, Volume: 122, Issue:8

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Drug Therapy, Combination; Fluorouracil; Humans; NADP; Oxidoreductases; Prodrugs; Rats

2002

Other Studies

18 other study(ies) available for fluorouracil and nadp

ArticleYear
[Participation of non-specific rat liver microsome oxidases in destruction of Nl-furanidylpyrimidines].
    Biulleten' eksperimental'noi biologii i meditsiny, 1977, Volume: 83, Issue:2

    Topics: Animals; Biotransformation; Fluorouracil; Male; Microsomes, Liver; NADP; Proadifen; Rats; Tegafur

1977
Comparative studies on the metabolism of 2-(tetrahydrofuryl)-5-fluorouracil and 5-fluorouracil.
    Gan, 1977, Volume: 68, Issue:5

    Topics: Alanine; Animals; DNA, Neoplasm; Fluorouracil; In Vitro Techniques; Male; Mice; Microsomes, Liver; NADP; Neoplasms, Experimental; Nucleic Acid Precursors; Rats; Tegafur; Tissue Distribution

1977
[Effect of x-rays and inhibitors of protein synthesis on the synthesis of chlorophyll and NADP-linked glyceraldehyde 3-phosphate dehydrogenase in greening Euglena gracilis].
    Archiv fur Mikrobiologie, 1973, Volume: 92, Issue:4

    Topics: Chloramphenicol; Chlorophyll; Chlorophyta; Dactinomycin; Darkness; Euglena gracilis; Fluorouracil; Glyceraldehyde-3-Phosphate Dehydrogenases; Light; NADP; Photosynthesis; Plant Proteins; Protein Biosynthesis; Radiation Effects; Rifampin; Time Factors; Transcription, Genetic

1973
Fluorouracil effect on cytochrome c reductase activity of rat liver cell endoplasmic reticulum following partial hepatectomy.
    Upsala journal of medical sciences, 1973, Volume: 78, Issue:2

    Topics: Animals; Cytochrome Reductases; Endoplasmic Reticulum; Fluorouracil; Hepatectomy; Liver; Male; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADP; Rats; Stimulation, Chemical

1973
Induction by gonadal hormones of hepatic lipogenic enzyme activity in immature pullets.
    The Journal of endocrinology, 1974, Volume: 61, Issue:1

    Topics: Analysis of Variance; Animals; ATP Citrate (pro-S)-Lyase; Body Weight; Chickens; Cycloheximide; DNA; Enzyme Induction; Estradiol; Female; Fluorouracil; Injections, Intramuscular; Liver; Malate Dehydrogenase; NADP; Organ Size; Progesterone; RNA; Testosterone

1974
Action of puromycin and 5-fluorouracil on the adrenal responsiveness to corticotrophin.
    Experientia, 1965, Apr-15, Volume: 21, Issue:4

    Topics: Adenine Nucleotides; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Fluorouracil; Glucosyltransferases; In Vitro Techniques; NADP; Phosphates; Protein Biosynthesis; Puromycin; Rats; RNA

1965
Intestinal epithelial enzyme abnormalities induced by 5-fluorouracil: translocation of NADPH2-dehydrogenase.
    The American journal of digestive diseases, 1967, Volume: 12, Issue:6

    Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Autopsy; Biopsy; Colitis, Ulcerative; Colon; Esterases; Fluorouracil; Histocytochemistry; Humans; Intestinal Mucosa; Intestine, Small; Jejunum; Mice; NADP; Oxidoreductases

1967
Prevention of 5-FU induced NADPH-D translocation in colonic epithelium by antibiotics and the effect on the intestinal bacterial flora.
    Scandinavian journal of gastroenterology, 1967, Volume: 2, Issue:3

    Topics: Animals; Clostridium; Colon; Epithelium; Escherichia; Fluorouracil; Histocytochemistry; Lactobacillus; Mice; NADP; Neomycin; Oxidoreductases; Penicillins; Streptococcus

1967
[Determination, properties and inhibition of thymidilate synthetase in immature myeloid blood and bone marrow cells].
    Blut, 1971, Volume: 22, Issue:6

    Topics: Bone Marrow; Bone Marrow Cells; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Hydrogen-Ion Concentration; Ions; Leukocytes; Magnesium; Mercaptoethanol; Methyltransferases; NADP; Transferases; Tritium; Uracil Nucleotides

1971
Synthesis and biological evaluation of neutral derivatives of 5-fluoro-2'-deoxyuridine 5'-phosphate.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:8

    Topics: 5'-Nucleotidase; Alkaline Phosphatase; Animals; Arabinonucleotides; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Fluorouracil; Leukemia P388; Mice; Microsomes, Liver; NADP; Nucleotidases; Phosphoric Diester Hydrolases

1983
A comparative analysis of translated dihydropyrimidine dehydrogenase cDNA; conservation of functional domains and relevance to genetic polymorphisms.
    Pharmacogenetics, 2002, Volume: 12, Issue:2

    Topics: Amino Acid Sequence; Animals; Binding Sites; Caenorhabditis elegans; Cattle; Cloning, Molecular; Dihydrouracil Dehydrogenase (NADP); DNA, Complementary; Drosophila; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Fluorouracil; Humans; Mice; Molecular Sequence Data; NADP; Oxidoreductases; Polymorphism, Genetic; Rats; Sequence Homology, Amino Acid; Swine; Uracil

2002
THE INFLUENCE OF PHENOBARBITAL ADMINISTRATION UPON THE "SOLUBLE" NADP-REQUIRING ENZYMES IN LIVER.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Aminopyrine; Benzopyrenes; Citrates; Diphenhydramine; Ethionine; Fluorouracil; Gluconates; Hexosephosphates; Isocitrate Dehydrogenase; Liver; Mercaptopurine; Methylcholanthrene; NADP; Oxidoreductases; Pharmacology; Phenobarbital; Phenylalanine; Rats; Research; Uracil

1964
METABOLIC EVENTS DURING THE FORMATION OF A PHOTOSYNTHETIC FROM A NONPHOTOSYNTHETIC CELL.
    Brookhaven symposia in biology, 1964, Volume: 16

    Topics: Arsenicals; Azides; Beryllium; Chloramphenicol; Chlorophyll; Chloroplasts; Cyanides; Dihydrolipoamide Dehydrogenase; Dinitrophenols; Euglena; Fluorides; Fluorouracil; Fructose-Bisphosphate Aldolase; Malonates; NADP; Nucleoproteins; Pharmacology; Photosynthesis; Proteins; Research; Ribonucleases; Ribosomes; RNA

1964
Overexpression of cytochrome P450 NADPH reductase sensitises MDA 231 breast carcinoma cells to 5-fluorouracil: possible mechanisms involved.
    Toxicology in vitro : an international journal published in association with BIBRA, 2008, Volume: 22, Issue:3

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Female; Fluorouracil; Glutathione; Humans; Microsomes; Mitomycin; NADP; NADPH-Ferrihemoprotein Reductase; Reactive Oxygen Species; Transfection; Vincristine

2008
5-fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits.
    Oncotarget, 2015, Dec-08, Volume: 6, Issue:39

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Biomarkers, Tumor; Carrier Proteins; Cell Proliferation; Colonic Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Female; Fluorouracil; HT29 Cells; Humans; Membrane Proteins; Mice, Nude; Mitochondria; NADP; Neoplastic Stem Cells; Oxidation-Reduction; Oxidative Phosphorylation; Phenotype; Pyruvate Kinase; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays

2015
IDH1 R132H Mutation Enhances Cell Migration by Activating AKT-mTOR Signaling Pathway, but Sensitizes Cells to 5-FU Treatment as NADPH and GSH Are Reduced.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Agammaglobulinaemia Tyrosine Kinase; Blotting, Western; Cell Line; Cell Movement; Cell Proliferation; Fluorouracil; Glioma; Glutathione; Humans; Isocitrate Dehydrogenase; Mutation; NADP; Protein-Tyrosine Kinases; Signal Transduction; TOR Serine-Threonine Kinases

2017
Inhibition of GOT1 sensitizes colorectal cancer cells to 5-fluorouracil.
    Cancer chemotherapy and pharmacology, 2017, Volume: 79, Issue:4

    Topics: Antimetabolites, Antineoplastic; Aspartate Aminotransferase, Cytoplasmic; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Fluorouracil; HT29 Cells; Humans; Lentivirus; NADP; Oxidative Stress; Reactive Oxygen Species; RNA, Small Interfering; Transfection

2017
6PGD Upregulation is Associated with Chemo- and Immuno-Resistance of Renal Cell Carcinoma via AMPK Signaling-Dependent NADPH-Mediated Metabolic Reprograming.
    The American journal of the medical sciences, 2020, Volume: 360, Issue:3

    Topics: AMP-Activated Protein Kinases; Carcinoma, Renal Cell; Cell Line; Cell Line, Tumor; Cellular Reprogramming; Drug Resistance, Neoplasm; Enzyme Activation; Fluorouracil; Gene Knockdown Techniques; Humans; Immunotherapy; Interferon-alpha; Kidney; Kidney Neoplasms; NADP; Phosphogluconate Dehydrogenase; RNA, Small Interfering; Signal Transduction; Up-Regulation

2020