fluorouracil and n(1),n(11)-diethylnorspermine

fluorouracil has been researched along with n(1),n(11)-diethylnorspermine in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carew, J; Choi, W; Dupart, J; Gerner, EW; Hamilton, SR; Huang, P; Proctor, L; Ramdas, L; Zhang, W1
Chiao, PJ; Choi, W; Feng, Y; Gerner, EW; Hamilton, SR; Proctor, L; Xia, Q; Zhang, W1
Clark, K; Diegelman, P; Fakih, M; Hector, S; Kisiel, ND; Kramer, DL; Pendyala, L; Porter, CW; Tummala, R; Vujcic, S1
Billam, M; Casero, RA; Davidson, NE; Hacker, A; Pledgie-Tracy, A; Sobolewski, MD; Woster, PM; Zhang, Z1

Other Studies

4 other study(ies) available for fluorouracil and n(1),n(11)-diethylnorspermine

ArticleYear
Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells.
    The Journal of biological chemistry, 2005, Feb-04, Volume: 280, Issue:5

    Topics: Acetyltransferases; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antioxidants; Apoptosis; Caspase 9; Caspases; Cytochromes c; Drug Synergism; Fluorouracil; Gene Deletion; HCT116 Cells; Humans; Hydrogen Peroxide; Mitochondria; Polyamines; Spermine; Transcription, Genetic; Tumor Suppressor Protein p53

2005
Inactivation of IkappaB contributes to transcriptional activation of spermidine/spermine N(1)-acetyltransferase.
    Molecular carcinogenesis, 2006, Volume: 45, Issue:9

    Topics: Acetyltransferases; Antineoplastic Agents; Colonic Neoplasms; Cycloheximide; Dactinomycin; Fluorouracil; Humans; I-kappa B Proteins; Membrane Potentials; Mitochondria; Mitochondrial Membranes; NF-kappa B; NF-kappa B p50 Subunit; Promoter Regions, Genetic; Protein Biosynthesis; Protein Synthesis Inhibitors; Response Elements; Spermine; Transcription Factor RelA; Transcriptional Activation; Tumor Cells, Cultured

2006
Polyamine catabolism in colorectal cancer cells following treatment with oxaliplatin, 5-fluorouracil and N1, N11 diethylnorspermine.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:3

    Topics: Acetyltransferases; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Fluorouracil; Gene Expression; Humans; Organoplatinum Compounds; Oxaliplatin; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Rectal Neoplasms; Spermine

2008
The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines.
    Cancer chemotherapy and pharmacology, 2010, Volume: 65, Issue:6

    Topics: Acetyltransferases; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Female; Fluorouracil; Gene Expression Regulation, Enzymologic; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Oxidoreductases Acting on CH-NH Group Donors; Paclitaxel; Polyamine Oxidase; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Spermine; Xenograft Model Antitumor Assays

2010