fluorouracil has been researched along with metronidazole in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (33.33) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 6 (22.22) | 29.6817 |
| 2010's | 10 (37.04) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Levin, VA | 1 |
| Fujiwara, H; Kai, J; Masuda, T; Nakamura, K; Ueda, I | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Dragon, LH; Ettinger, DS; Klein, J; Order, SE; Sgagias, M | 1 |
| Giles, GR; Hannam, TW; Kelly, JP | 1 |
| Bell, PR; Macpherson, S; Windle, R | 1 |
| Kornfeld, S; Minnich, V; Smith, ME; Thompson, D | 1 |
| Ayoub, J; Bardakji, Z; Besner, JG; Jolivet, J; Langelier, Y | 1 |
| Kurpeshev, OK | 1 |
| Schmerold, I; Tempel, K; Winkle, J; Wulffius-Kock, M | 1 |
| Tannock, IF | 1 |
| Aliev, VA; Barsukov, IuA; Glebovskaia, VV; Gordeev, SS; Kuz'michev, DV; Malikhov, AG; Oltarzhevskaia, ND; Osombaev, MSh; Perevoshchikov, AG; Tkachev, SI; Tsariuk, VF | 1 |
| Barsukov, YA; Fedyanin, MY; Gordeyev, SS; Perevoshikov, AG; Tkachev, SI | 1 |
| Chen, DP; Li, MY; Liang, YY; Liu, JQ; Qi, B; Yin, WJ | 1 |
| Fukumoto, T; Fukutake, T; Katada, F; Murayama, S; Sato, S; Shibayama, H | 1 |
| Dai, W; Kong, X; Peng, X; Quan, H; Xiang, Y; Yang, C | 1 |
1 review(s) available for fluorouracil and metronidazole
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 trial(s) available for fluorouracil and metronidazole
| Article | Year |
|---|---|
[Effectiveness of neoadjuvant chemoradiotherapy of locally advanced rectal cancer in conjunction with local hyperthermia and metronidazole].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Hyperthermia, Induced; Infusions, Intravenous; Male; Metronidazole; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant; Rectal Neoplasms; Treatment Outcome | 2011 |
Phase II study of concomitant chemoradiotherapy with local hyperthermia and metronidazole for locally advanced fixed rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Hyperthermia, Induced; Male; Metronidazole; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Radiation-Sensitizing Agents; Rectal Neoplasms; Treatment Outcome; Young Adult | 2013 |
Glycididazole sodium combined with radiochemotherapy for locally advanced nasopharyngeal carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Case-Control Studies; Chemoradiotherapy; Cisplatin; Female; Fluorouracil; Folic Acid; Follow-Up Studies; Humans; Male; Metronidazole; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Staging; Prognosis; Survival Rate | 2014 |
23 other study(ies) available for fluorouracil and metronidazole
| Article | Year |
|---|---|
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability.
Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Male; Models, Biological; Molecular Weight; Rats; Rats, Inbred F344; Solubility; Structure-Activity Relationship | 1980 |
Thermodynamic aspects of hydrophobicity and the blood-brain barrier permeability studied with a gel filtration chromatography.
Topics: Blood-Brain Barrier; Chromatography, Gel; Hydrogen Bonding; Micelles; Permeability; Solubility; Thermodynamics | 1996 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Isotopic immunoglobulin in an integrated multimodal treatment program for a primary liver cancer: a case report.
Topics: Adenoma, Bile Duct; Adult; Carcinoembryonic Antigen; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Iodine Radioisotopes; Liver Neoplasms; Metronidazole; Radionuclide Imaging | 1979 |
The cytocidal action of metronidazole in combination with other antineoplastic agents.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Hypoxia; Methotrexate; Metronidazole; Mice; Neoplasms, Experimental | 1979 |
Neutropenia associated with metronidazole.
Topics: Agranulocytosis; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Metronidazole; Neutropenia; Postoperative Care; Rectal Neoplasms | 1979 |
Detection of mutagenic activity in human urine using mutant strains of Salmonella typhimurium.
Topics: Antineoplastic Agents; Biological Assay; Cyclophosphamide; Ethylnitrosourea; Fluorouracil; Humans; Mechlorethamine; Melphalan; Metronidazole; Mitomycins; Mutagens; Neoplasms; Salmonella typhimurium | 1976 |
5-Fluorouracil-metronidazole combination therapy in metastatic colorectal cancer. Clinical, pharmacokinetic and in vitro cytotoxicity studies.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Colonic Neoplasms; Female; Fluorouracil; Humans; Kinetics; Male; Metabolic Clearance Rate; Metronidazole; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms | 1986 |
[Modification of separate and combined effects of hyperthermia and ionizing radiation on normal tissues].
Topics: Animals; Cycloheximide; Dactinomycin; Ethanol; Fluorouracil; Glucose; Hot Temperature; Metronidazole; Mice; Procaine; Radiation Injuries, Experimental; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiation, Ionizing; Serotonin; Skin | 1986 |
[Semiconservative and unscheduled DNA-synthesis of rat thymocytes under the influence of some radioprotecting and radiosensitizing agents (author's transl)].
Topics: Acetophenones; Animals; beta-Aminoethyl Isothiourea; Bleomycin; Cysteamine; Cysteine; Cytarabine; Ditiocarb; DNA; Doxorubicin; Ethidium; Ethylmaleimide; Female; Fluorouracil; Glutathione; Mercaptoethanol; Metronidazole; Nitrofurazone; Radiation-Protective Agents; Radiation-Sensitizing Agents; Rats; T-Lymphocytes; Tiopronin | 1982 |
In vivo interaction of anti-cancer drugs with misonidazole or metronidazole: methotrexate, 5-fluorouracil and adriamycin.
Topics: Animals; Body Weight; Doxorubicin; Drug Therapy, Combination; Fibrosarcoma; Fluorouracil; Leukocyte Count; Male; Mammary Neoplasms, Experimental; Methotrexate; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental | 1980 |
[A case of acute leukoencephalopathy induced by a combination of 5-fluorouracil and metronidazole].
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Drug Therapy, Combination; Fatal Outcome; Female; Fluorouracil; Humans; Leucovorin; Leukoencephalopathies; Magnetic Resonance Imaging; Metronidazole; Neuroimaging; Organoplatinum Compounds | 2018 |
Multifunctional nanocomposites MGO/FU-MI inhibit the proliferation of tumor cells and enhance the effect of chemoradiotherapy in vivo and in vitro.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chemoradiotherapy; Fluorouracil; Humans; Magnesium Oxide; Metronidazole; Mice; Mice, Inbred C57BL; Nanocomposites; Neoplasms; Radiation Tolerance; Reactive Oxygen Species | 2020 |