fluorouracil has been researched along with metoclopramide in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (32.43) | 18.7374 |
| 1990's | 8 (21.62) | 18.2507 |
| 2000's | 11 (29.73) | 29.6817 |
| 2010's | 6 (16.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Busnardo, B; Casara, D; De Besi, P; Fiorentino, MV; Girelli, ME; Nacamulli, D; Simioni, N; Toso, S; Zorat, P | 1 |
| Guillén Lloveria, G; Mayordomo Cámara, JJ; Sáenz Cusi, A; Sáez Martínez, MJ; Tres Sánchez, A | 1 |
| Bonneterre, J; Bons, J; Chevallier, B; Fargeot, P; Metz, R; Paes, D; Pujade-Lauraine, E; Spielmann, M; Tubiana-Hulin, M | 1 |
| Giannarelli, D; Marolla, P; Nardi, M; Pinnaró, P; Pollera, CF; Terzoli, E | 1 |
| Biran, S; Cass, Y; Gera, C; Gez, E; Nathan, S; Ochayon, L; Rubello, E; Sulkes, A | 1 |
| Ballatori, E; Basurto, C; del Favero, A; Minotti, V; Roila, F; Tonato, M | 2 |
| Lam, YM; Martin, WM; Shiu, W; Tsang, V; Zacharia, A | 1 |
| Arihiro, T; Dozono, H; Morimoto, O; Ochiai, K; Sasaki, H; Takahashi, S; Terashima, Y; Tsuruoka, M; Yasuda, M; Yokoyama, S | 1 |
| Ben-Baruch, N; Ben-Yosef, R; Biran, S; Brufman, G; Gez, E; Uziely, B; Warner-Efraty, E; Yitzhaki, N | 1 |
| Gerra, C; Gez, E; Goodman, S; Isacson, R; Sulkes, A | 1 |
| Ballatori, E; Basurto, C; Minotti, V; Roila, F; Tonato, M | 1 |
| Bruzzi, P; Campora, E; Chiara, S; Rosso, R; Scarsi, P | 1 |
| Niemiec, PW; Vanderveen, TW | 1 |
| Bui, BN; Chauvergne, J; David, M; Durand, M; Hoerni, B; Mauriac, L | 1 |
| Ang, PT; Khoo, KS; Tan, EH | 1 |
| Latreille, J; Levitt, M; Lofters, WS; Perrault, DJ; Potvin, M; Rayner, HL; Warner, E; Warr, D; Wilson, KS; Yelle, L | 1 |
| Barrenetxea, G; Centeno, MM; de la Rica, M; Rodríguez-Escudero, FJ; Romero, H; Schneider, J | 1 |
| Brown, RS; Brown, TK; Gaze, MN; Hoare, D | 1 |
| Bosnjak, SM; Mitrovi, LB; Nesković-Konstantinović, ZB; Radulović, SS; Susnjar, S | 1 |
| Ahn, JH; Bahng, H; Chang, HM; Kang, WC; Kang, YK; Kim, TW; Kim, WK; Lee, JS; Park, JS | 1 |
| Chang, LC; Lee, DK; Wang, DP; Wong, CY | 1 |
| Matsumoto, T; Mikami, T; Momokawa, K; Nakamura, Y; Sakayauchi, T; Sasaki, T; Watanabe, T | 1 |
| Ito, Y; Tomono, H; Watanabe, T | 1 |
| Bang, YJ; Chie, EK; Ha, SW; Im, SA; Jang, JY; Kim, K; Kim, SW; Kim, TY; Oh, DY | 1 |
| Eksborg, S; Lönnqvist, PA; Öbrink, E; Oddby-Muhrbeck, E; Rotstein, S | 1 |
| Brunetti, AE; Nardulli, P; Russano, M; Silvestris, N | 1 |
1 review(s) available for fluorouracil and metoclopramide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
15 trial(s) available for fluorouracil and metoclopramide
| Article | Year |
|---|---|
[Antiemetic treatments associated with antineoplastic chemotherapy].
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lorazepam; Methylprednisolone; Metoclopramide; Vincristine; Vomiting | 1990 |
A randomized double-blind comparison of ondansetron and metoclopramide in the prophylaxis of emesis induced by cyclophosphamide, fluorouracil, and doxorubicin or epirubicin chemotherapy.
Topics: Administration, Oral; Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Double-Blind Method; Doxorubicin; Drug Administration Schedule; Epirubicin; Fluorouracil; Humans; Imidazoles; Infusions, Intravenous; Metoclopramide; Middle Aged; Nausea; Ondansetron; Randomized Controlled Trials as Topic; Time Factors; Vomiting | 1990 |
Effective control of CMF-related emesis with high-dose dexamethasone: results of a double-blind crossover trial with metoclopramide and placebo.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Metoclopramide; Middle Aged; Random Allocation; Vomiting | 1989 |
Methylprednisolone versus metoclopramide as antiemetic treatment in patients receiving adjuvant cyclophosphamide, methotrexate, 5-fluorouracil (CMF) chemotherapy: a randomized crossover blind study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Metoclopramide; Middle Aged; Randomized Controlled Trials as Topic; Vomiting | 1989 |
Double-blind controlled trial of the antiemetic efficacy and toxicity of methylprednisolone (MP), metoclopramide (MTC) and domperidone (DMP) in breast cancer patients treated with i.v. CMF.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Domperidone; Double-Blind Method; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Metoclopramide; Middle Aged; Nausea; Vomiting | 1987 |
A randomised cross-over trial comparing low-dose metoclopramide and chlorpromazine with high-dose metoclopramide in Chinese patients with advanced cancer receiving cisplatinum and 5-fluorouracil.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorpromazine; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Eating; Female; Fluorouracil; Hong Kong; Humans; Male; Metoclopramide; Middle Aged; Nausea; Neoplasms; Random Allocation; Time Factors; Vomiting | 1987 |
Methylprednisolone versus metoclopramide for prevention of nausea and vomiting in breast cancer patients treated with intravenous cyclophosphamide methotrexate 5-fluorouracil: a double-blind randomized study.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Double-Blind Method; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Metoclopramide; Middle Aged; Nausea; Random Allocation; Vomiting | 1988 |
Evaluation of the antiemetic activity of bromopride in cancer patients treated with i.v. CMF.
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Metoclopramide; Middle Aged | 1985 |
The antiemetic efficacy of methylprednisolone compared with metoclopramide in outpatients receiving adjuvant CMF chemotherapy for breast cancer: a randomized trial.
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Metoclopramide; Middle Aged; Random Allocation | 1985 |
Control of emesis by intravenous granisetron in breast cancer patients treated with 5-FU, epirubicin and cyclophosphamide.
Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Constipation; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Flushing; Granisetron; Headache; Humans; Injections, Intravenous; Metoclopramide; Middle Aged; Nausea; Tablets; Vomiting | 1994 |
Ondansetron compared with dexamethasone and metoclopramide as antiemetics in the chemotherapy of breast cancer with cyclophosphamide, methotrexate, and fluorouracil.
Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Metoclopramide; Middle Aged; Nausea; Ondansetron; Regression Analysis; Vomiting | 1993 |
Chemotherapy-induced emesis: management of early and delayed emesis in milder emetogenic regimens.
Topics: Administration, Oral; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Epirubicin; Female; Fluorouracil; Humans; Infusions, Intravenous; Methotrexate; Metoclopramide; Ondansetron; Patient Satisfaction; Quality of Life; Surveys and Questionnaires; Vomiting | 1996 |
High efficacy of a single oral dose of ondansetron 8 mg versus a metoclopramide regimen in the prevention of acute emesis induced by fluorouracil, doxorubicin and cyclophosphamide (FAC) chemotherapy for breast cancer.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Metoclopramide; Middle Aged; Ondansetron; Prospective Studies; Vomiting | 2000 |
Nephrotoxicity of heptaplatin: a randomized comparison with cisplatin in advanced gastric cancer.
Topics: Acute Disease; Adenocarcinoma; Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Creatinine; Dexamethasone; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Fluorouracil; Gastrectomy; Humans; Infusions, Intravenous; Kidney Diseases; Kidney Function Tests; Leukopenia; Male; Malonates; Metabolic Clearance Rate; Metoclopramide; Middle Aged; Ondansetron; Organoplatinum Compounds; Proteinuria; Stomach Neoplasms; Survival Analysis; Vomiting | 2002 |
Optimal control of nausea and vomiting with a three-drug antiemetic regimen with aprepitant in metastatic pancreatic cancer patients treated with first-line modified FOLFIRINOX.
Topics: Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Benztropine; Camptothecin; Dexamethasone; Drug Combinations; Female; Fluorouracil; Haloperidol; Humans; Leucovorin; Male; Metoclopramide; Morpholines; Nausea; Organoplatinum Compounds; Pancreatic Neoplasms; Vomiting | 2013 |
21 other study(ies) available for fluorouracil and metoclopramide
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Combined chemotherapy with bleomycin, adriamycin, and platinum in advanced thyroid cancer.
Topics: Adenocarcinoma; Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Betamethasone; Bleomycin; Carcinoma; Carmustine; Cisplatin; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Metoclopramide; Middle Aged; Nausea; Thyroid Neoplasms; Vincristine | 1991 |
[The prevention of CDDP-induced emesis with a combination regimen including metoclopramide, dexamethasone, droperidol and diphenhydramine].
Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dexamethasone; Diphenhydramine; Doxorubicin; Droperidol; Female; Fluorouracil; Humans; Metoclopramide; Middle Aged; Nausea; Vomiting | 1987 |
High-dose metoclopramide and dexamethasone as an antiemetic in outpatients receiving chemotherapy for breast cancer. Second study.
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Dexamethasone; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Metoclopramide; Middle Aged; Nausea; Vomiting | 1987 |
High-dose metoclopramide and dexamethasone as an antiemetic in chemotherapy of breast cancer.
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Metoclopramide | 1986 |
Compatibility considerations in parenteral nutrient solutions.
Topics: Adrenal Cortex Hormones; Albumins; Aminophylline; Amphotericin B; Anti-Bacterial Agents; Bicarbonates; Calcium; Cimetidine; Digoxin; Drug Incompatibility; Drug Stability; Fat Emulsions, Intravenous; Fluorouracil; Heparin; Humans; Hydrochloric Acid; Iron-Dextran Complex; Metoclopramide; Narcotics; Parenteral Nutrition; Parenteral Nutrition, Total; Phosphates; Sodium Bicarbonate; Trace Elements; Vitamins | 1984 |
Cyclophosphamide, methotrexate, and 5-FU (CMF)-induced nausea and vomiting: a controlled study with high-dose metoclopramide.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Metoclopramide; Middle Aged; Nausea; Random Allocation; Time Factors | 1984 |
An audit of antiemetic use with CMF chemotherapy.
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Drug Therapy, Combination; Female; Fluorouracil; Granisetron; Humans; Medical Records; Methotrexate; Metoclopramide; Retrospective Studies; Serotonin Antagonists; Treatment Outcome; Vomiting | 1998 |
Stability of fluorouracil-metoclopramide hydrochloride admixture.
Topics: Antimetabolites, Antineoplastic; Chromatography, High Pressure Liquid; Drug Combinations; Drug Stability; Drug Storage; Fluorouracil; Metoclopramide | 1995 |
[Effect of steroid on antiemetic for side effect of anticancer chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Dexamethasone; Drug Administration Schedule; Drug Therapy, Combination; Esophageal Neoplasms; Fluorouracil; Humans; Male; Metoclopramide; Middle Aged; Nausea; Organoplatinum Compounds; Serotonin Antagonists; Stomach Neoplasms; Vomiting, Anticipatory | 2005 |
[Successful antiemetic treatment of TSUMURA Rikkunshi-to Extract Granules for ethical use in addition to other antiemetic agents in neoadjuvant chemotherapy for an advanced breast cancer patient].
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Dexamethasone; Drug Administration Schedule; Drugs, Chinese Herbal; Epirubicin; Female; Fluorouracil; Granisetron; Humans; Lymph Nodes; Lymphatic Metastasis; Mastectomy, Segmental; Metoclopramide; Middle Aged | 2006 |
Ramosetron for the prevention of nausea and vomiting during 5-fluorouracil-based chemoradiotherapy for pancreatico-biliary cancer.
Topics: Adult; Aged; Antiemetics; Benzimidazoles; Biliary Tract Neoplasms; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Male; Metoclopramide; Middle Aged; Nausea; Ondansetron; Pancreatic Neoplasms; Radiotherapy, Adjuvant; Vomiting | 2009 |
Is there an association between PONV and chemotherapy-induced nausea and vomiting?
Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Betamethasone; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease Resistance; Droperidol; Epirubicin; Female; Fluorouracil; Granisetron; Humans; Mastectomy; Methotrexate; Metoclopramide; Middle Aged; Models, Biological; Narcotics; Nausea; Ondansetron; Postoperative Nausea and Vomiting; Prospective Studies; Risk Factors; Vomiting | 2013 |