fluorouracil has been researched along with methotrexate in 3760 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1877 (49.92) | 18.7374 |
| 1990's | 901 (23.96) | 18.2507 |
| 2000's | 661 (17.58) | 29.6817 |
| 2010's | 278 (7.39) | 24.3611 |
| 2020's | 43 (1.14) | 2.80 |
| Authors | Studies |
|---|---|
| Angier, RB; Child, RG; Citarella, RV; Durr, FE; Fabio, PF; Murdock, KC; Wallace, RE | 1 |
| Hansch, C; Khwaja, TA; Selassie, CD | 1 |
| Bussolari, JC; Chen, SF; Panzica, RP; Ramesh, K; Stoeckler, JD | 1 |
| Barrero, AF; Cabrera, E; Chahboun, R; Cortés, M; Lara, M; Manzaneda, EA; Rivas, AR | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Benfenati, E; Raska, I; Toropov, AA; Toropova, AP | 1 |
| Abdel-Aziz, AA; Abdel-Hamide, SG; Abou-Zeid, LA; Al-Obaid, AM; Al-Omar, MA; Al-Omary, FA; El-Azab, AS; El-Subbagh, HI; Habib, el-SE; Nagi, MN | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Cao, SL; Gao, RT; Han, Y; Li, ZF; Liao, J; Mao, BB; Wang, Y; Xiahou, ZK; Xu, X; Yuan, CZ; Zhao, BL | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Abulfadl, YS; Al-Omary, FA; Al-Rashood, ST; El-Messery, SM; El-Subbagh, HI; Hassan, GS; Shabayek, MI | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Al-Rashood, ST; El-Messery, SM; El-Subbagh, HI; Habib, EE; Hassan, GS; Nagi, MN | 1 |
| Li, H; Liu, J; Tian, C; Wang, M; Wang, X; Xue, L; Yang, J; Yuan, M; Zhang, Z | 1 |
| Gao, F; Wang, T; Xiao, J; Zhang, X | 1 |
| Xu, Z; Zhang, L | 1 |
| Angeli, A; Bua, S; Ece, A; Gul, HI; Kurosaki, K; Masuda, Y; Sakagami, H; Satoh, K; Supuran, CT; Uesawa, Y; Yamali, C; Yokose, S | 1 |
| Borsos, T; Ohanian, SH; Segerling, M | 2 |
| Calvert, AH; Hill, BT; Hughes, KB; Price, LA; Shaw, HJ | 1 |
| Ryall, RD; Tattersall, S | 1 |
| Just-Viera, JO; Silva, JE | 1 |
| DeWys, WD | 1 |
| Cohen, SC; Gabelnick, HL; Goldin, A; Johnson, RK | 1 |
| Holoye, PY; Johnson, DE; Samuels, ML | 1 |
| Bertino, JR; Boston, B; Capizzi, RL | 1 |
| Kaufmann, M; Mattern, J; Volm, M; Wayss, K | 2 |
| Carter, SK; Goldsmith, MA | 1 |
| Cuschieri, A; Swain, C | 1 |
| DiSaia, PJ; Forney, JP; Futoran, RJ; Morrow, CP | 1 |
| Blackstein, ME; Chapnik, JS | 1 |
| Bychkov, MB; Chebotareva, LI; Lichinitser, MR; Nivinskaia, MM; Starichkov, MS | 1 |
| Alberto, P; Cavalli, F; Jungi, F; Martz, G | 1 |
| Ayala, AG; Bracken, RB; Johnson, DE; Samuels, ML | 1 |
| Donegan, WL; Harris, P | 1 |
| Price, LA; Stathopoulos, G; Wiltshaw, E | 1 |
| Boyle, LE; Holoye, PY; Lanzotti, VJ; Samuels, ML; Smith, TL; Thomas, DR | 1 |
| Depierre, A; Israel, L | 2 |
| Kaidbey, KH | 1 |
| Maier, P; Schmid, W | 1 |
| Boyle, LE; Holoye, PY; Johnson, DE; Lanzotti, VJ; Samuels, ML; Smith, TL | 1 |
| Bates, T; Brinkley, D; Edelstyn, GA; MacRae, KD; Spittle, MF; Wheeler, T | 1 |
| Legha, SS; Muggia, FM | 1 |
| Carter, SK; Wasserman, TH | 2 |
| Gajcy, H; Koziorowska, J; Pieńkowska, K; Tautt, J | 1 |
| Davis, TE; Rose, DP | 1 |
| Chabner, BA; Myers, CE; Oliverio, VT | 1 |
| Ford, CH; Newman, CE | 1 |
| Ang, J; Habs, M; Schmähl, D | 1 |
| Burchenal, JH; Chisholm, J; Kalaher, K; O'Toole, T | 1 |
| Carter, SK | 5 |
| Golbey, RB | 1 |
| Boesen, E; Derry, CD; Drake, SR; Hanham, IW; Mair, G; McKenzie, C; Senanayake, F; Skeggs, DB; Stoll, BA; Wilson, R | 1 |
| Hartmann, D; Obrecht, JP; Obrist, R | 1 |
| Barlow, JJ; Piver, MS; Xynos, FP | 1 |
| Bender, RA; Chabner, BA; Cohen, M; Doroshow, JH; Hande, KR; Locker, GY; Murinson, DS; Myers, CE; Zwelling, LA | 1 |
| Armstrong, AL; Meeker, WR | 1 |
| Byers, RM; Gard, DA; Goepfert, H; Guillamondegui, OM; Holoye, PY; Jesse, RH | 1 |
| Bates, T; Brinkley, D; Edelstyn, GA; Kitchen, G; MacRae, KD; Nicol, NT; Spittle, M; Wheeler, T | 1 |
| Jehn, U; Kohlschütter, B | 1 |
| Holland, JF | 3 |
| Bianco, A; DeWys, WD; Merrill, JM; Reich, S; Taylor, SG | 1 |
| Nitze, HR | 1 |
| Perlin, E | 1 |
| Biraghi, M; Curtarelli, G; Margulis, A; Scanni, A; Tomirotti, M | 1 |
| Capel, ID; Dorrell, HM; Jenner, M; Williams, DC | 1 |
| Chabner, BA; Donehower, RC; Myers, CE | 1 |
| Habs, M; Schmähl, D | 1 |
| Firusian, N; Hossfeld, DK; John, V | 1 |
| Anderson, T; Bender, RA; Canellos, GP; Chabner, BA; DeVita, VT; Fisher, RI; Hubbard, SP; Simon, RM; Young, RC | 1 |
| Costa, J; Garvin, AJ; Ozols, RF; Simon, RM; Young, RC | 1 |
| Cady, B; Oberfield, RA; Pazianos, AG; Salzman, FA | 1 |
| Doppman, JL; Dunnick, NR; Jones, RB; Myers, CE; Speyer, J | 1 |
| Montague, DK | 1 |
| Chabner, BA; Coleman, CN; Johns, DG; Myers, CE | 1 |
| Morgenthaler, FR; Pettavel, J | 1 |
| Bogden, AE; Esber, HJ; Kuo, EY; Taylor, DJ | 1 |
| Walker, MD; Weiss, HD | 1 |
| Lin, H | 2 |
| Habs, M; Schmähl, D; Sych, F | 1 |
| Elias, K | 1 |
| Cubilla, AL; Hajdu, SI | 1 |
| Oberfield, RA | 4 |
| Falkson, G | 2 |
| Livingston, RB | 1 |
| Bast, RC; Borsos, T; Greene, SL; Ohanian, SH; Rapp, HJ; Segerling, M; Zbar, B | 1 |
| Karrer, K; Pridun, N | 1 |
| Engeler, V; Otto, R; Zwicker, H | 1 |
| Denck, H; Karrer, K; Pridun, N | 2 |
| Chainuvati, T; Hitanant, S; Nilprabhassorn, P; Umsawasdi, T; Viranuvatti, V | 1 |
| Fernholz, HJ; Frik, W; Nüvemann, M | 1 |
| Carmo-Pereira, J; Costa, FO; Pimentel, P; Teles, AG | 1 |
| Atkins, LM; Glae, GR; Meischen, SJ; Smith, AB; Walker, EM | 1 |
| Kas'yanenko, IV | 1 |
| Band, P; Bauer, M; Carbone, PP; Tormey, D | 1 |
| Brinkley, DM; Cochrane, AM; Murray-Lyon, IM; Williams, R | 1 |
| Habs, G; Habs, M; Schmähl, D | 1 |
| Aisner, J; Elias, EG; Morris, D; Wiernik, PH | 1 |
| O'Dell, S; Reynolds, RD | 1 |
| Brunner, KW | 2 |
| Cady, B; Oberfield, RA; Wellwood, JM | 1 |
| Sarg, MJ | 1 |
| Deas, BW; Kennedy, PS | 1 |
| Laatsch, N | 1 |
| Louie, AC; Muggia, FM; Rozencweig, M; von Hoff, DD | 1 |
| Angove, RC; Jamieson, GG | 1 |
| Corder, MP; Flannery, EP; Herbst, KD; Justice, GR; Sheets, RF; Stone, WH | 1 |
| Anderson, G; Stewart-Jones, J; Thomas, G | 1 |
| Calabresi, P; Heppner, GH | 2 |
| Bertino, JR | 4 |
| Cano, JP; Carcassonne, Y; Meyer, G | 1 |
| Hayashi, M; Hozumi, M; Okabe, J | 1 |
| Byron, RL; Jacobs, W; Keating, J; Riihimaki, DU; Tan, MS; Yonemoto, RH | 1 |
| Germiniani, R; Lavorato, F; Pipino, G | 1 |
| Haskell, CM | 1 |
| Banfi, A; Bonadonna, G; Rossi, A; Valagussa, P; Veronesi, U | 1 |
| Alberto, P; Brunner, KW; Martz, G; Maurice, P; Obrecht, P; Senn, HJ; Sonntag, RW | 1 |
| Albert, NE; Andreone, PA; Breeding, JH; Sparks, FC | 1 |
| deKernion, JB | 1 |
| Bartolucci, A; Carpenter, J; Krauss, S; Smalley, RV; Vogel, C | 1 |
| Kenis, Y; Pinedo, HM | 1 |
| Fisher, B | 3 |
| Caffier, H; Rotte, K | 1 |
| Bonadonna, G; Rossi, A; Valagussa, P | 3 |
| Mouridsen, HT; Palshof, T | 2 |
| Bedikian, A; Bodey, GP; Burgess, MA; Hersh, EM; Mavligit, GM; Rodriguez, V; Valdivieso, M | 1 |
| Cooper, MR; Muss, HB; Richards, F; Spurr, CL; White, DR | 2 |
| Abeloff, MD; Ettinger, DS | 1 |
| Bonadonna, G; Rossi, A; Valagussa, P; Veronesi, U | 3 |
| Tanneberger, S | 1 |
| Blom, J; Bull, JM; Carbone, PP; Falkson, G; Li, SH; Perlin, E; Simon, R; Tormey, DC | 1 |
| Frederiksen, PL; Joergensen, ST; Mouridsen, HT; Roesdahl, K; Thomsen, J | 1 |
| Amgwerd, R; Bigler, R; Creux, G; Enderlin, F; Engelhart, G; Heinz, C; Hochueli, R; Jungi, WF; Lanz, R; Senn, HJ; Simeon, B; Sprenger, F; Wick, A | 1 |
| Seradour, B; Thomas, M | 1 |
| Desai, SA; DeWys, WD; Taylor, SG | 1 |
| Begent, RH; Hayward, JL; Knight, RK; Rubens, RD; Sexton, SA | 1 |
| Drings, P; Kaufmann, M; Kubli, F; Lammers, G | 1 |
| Berlie, J; Brulé, G; Carton, M; Chauvergne, J; Clavel, B; Gary-Bobo, J; Guerrin, J; Klein, T; Pommatau, E | 1 |
| Cooper, MR; Jackson, DV; Muss, HB; Rhyne, L; Richards, F; Spurr, CL; Stuart, JJ; White, DR | 1 |
| Bedikian, AY; Bodey, GP; Burgess, MA; Mavligit, GM; Rodriguez, V; Valdivieso, M | 1 |
| Bajetta, E; Banfi, A; Bonadonna, G; Brambilla, C; De Lena, M; Di Fronzo, G; Rilke, F; Rossi, A; Tancini, G; Valagussa, P; Veronesi, U; Zucali, R | 1 |
| Borisov, AI | 1 |
| Catalano, RB; Creech, RH; Engstrom, PF; Grotzinger, PJ; Harris, DT | 1 |
| Bonadonna, G; Brambilla, C; Valagussa, P | 1 |
| Friedman, MA; Sadée, W | 1 |
| Amgwerd, R; Bigler, R; Enderlin, F; Engelhart, G; Heinz, C; Hochuli, E; Jungi, WF; Lanz, R; Senn, HJ; Simeon, B; Sprenger, F; Wick, A | 1 |
| Alberto, P; Brunner, KW; Cavalli, F; Jungi, F; Martz, G | 1 |
| Abisatov, KhA | 1 |
| Boyes, DA; Gerulath, A; Klaassen, DJ; Levitt, M; Miller, AB; Pearson, JG | 1 |
| Arseneau, JC; Brodovsky, H; Bruckner, HW; Creech, R; Davis, TE; Falkson, G; Greenspan, E; Horton, J; Pagano, M; Slayton, RW | 1 |
| Engelsman, E; Hamersma, E; Schaake, C | 1 |
| Blumenschein, GR; Buzdar, AV; Gehan, EA; Gutterman, JU; Hersh, EM; Hortobágyi, GN; Tashima, CK; Yap, HY | 1 |
| Mason, B; Stephens, EJ; Wood, HF | 1 |
| DeVita, VT; Weiss, RB | 1 |
| Mayr, AC; Senn, HJ | 1 |
| Cocking, JB; Cwynarski, MT; Diffey, BL; Fox, CA; Jackson, GA; Mallinson, CN; Rake, MO; Wass, VJ | 1 |
| Barnard, R; Bush, H; Thatcher, N | 1 |
| Bajetta, E; Bonadonna, G; Marchini, S; Tancini, G; Valagussa, P; Veronesi, U | 1 |
| Fiebig, HH; Schmähl, D | 2 |
| Bruntsch, U; Gallmeier, WM | 2 |
| Hutchison, DJ; Mehta, BM | 1 |
| Hahn, P; Hallberg, O; Vikterlöf, KJ | 1 |
| Carmel, R | 1 |
| Fisher, RI; Young, RC | 1 |
| Hughes, LE; Jones, KD | 1 |
| Ellis, DJ; Newman, CE | 1 |
| Capel, ID; Pinnock, MH; Williams, DC | 1 |
| Allegra, JC; Lippman, ME | 1 |
| Ballesteros, P; Cueto, J; García Puche, JL; Mendiola, C; Rodríguez, PA; Talavera, MC | 1 |
| Recchione, C; Rossi, A | 1 |
| Carey, RW; Halpern, E; Kaufman, S; Kelley, RM; Lew, RA; Sohier, WD; Weitzman, SA | 1 |
| Ortiz, AE; Pepper, I; Silva, H | 1 |
| Adamoli, P; Annibali, E; Biraghi, M; Curtarelli, G; Fittipaldi, M; Licciardello, L; Scanni, A; Tomirotti, M; Trovato, M | 1 |
| Nemoto, T; Rosner, D; Snyderman, M | 1 |
| Cadman, E; Davis, L; Heimer, R | 1 |
| Cooper, RG; Glidewell, O; Holland, JF | 2 |
| Cześnin, K; Ploch, E; Sablińska, B | 1 |
| Noldus, B; Schmidt-Rhode, P; Schulz, KD; Weymar, P | 1 |
| Costanzi, JJ; Panettiere, FJ; Wolma, FJ | 1 |
| Costanza, ME; Vaage, J | 2 |
| Jungi, WF; Mayr, AC; Senn, HJ | 1 |
| Giles, GR; Hannam, TW; Kelly, JP | 1 |
| Drago, JR; Eckels, DD; Gershwin, ME; Goldman, LB; Maurer, RE | 1 |
| Becher, R; Bruntsch, U; Drings, P; Fritze, D; Gallmeier, WM; Kaufmann, M; Kempgens, U; Mayr, AC; Queisser, W; Senn, HJ | 1 |
| Diatchin, IuA; Kulikova, ML; Orlovskaia, LA | 1 |
| Blumenschein, GR; Bodey, GP; Buzdar, AU; Freireich, EJ; Gehan, EA; Hortobagyi, GN; Legha, SS; Smith, TL; Swenerton, KD | 1 |
| Geiger, W; Künzig, HJ; Schmidt-Rhode, P; Schulz, KD; Weymar, P | 1 |
| Nemoto, T; Rosner, D | 1 |
| Fujikura, R; Inaba, M; Sakurai, Y | 1 |
| Biran, S; Brufman, G; Schächner, E | 1 |
| Cramer, SJ; de Ruiter, J; van Putten, LM | 1 |
| Akao, T; Fujimoto, S; Itoh, B; Itoh, K; Kitsukawa, Y; Takahashi, M | 1 |
| Denck, H; Karrer, K; Pridun, N; Sighart, H | 1 |
| Ebeling, K; Spitzbart, H | 1 |
| Lumholtz, IB | 1 |
| Baker, JW; Dady, PJ; Ford, HT; Gazet, JC; McKinna, JC; Nash, AG; Powles, TJ; Russell, JA | 1 |
| Bender, RA; Warren, RD | 1 |
| Rohwedder, JJ; Sagastume, E | 1 |
| Khwaja, TA; Lee, YT | 1 |
| Bishun, NP; Reed, J; Williams, D | 1 |
| Bolton, PM | 1 |
| Bowen, D; Goldman, ID; White, JC | 1 |
| Fung, HL; Morrison, RA; Oseekey, KB | 1 |
| Vogel, CL | 1 |
| Jochimsen, PR; Pearlman, NW; Shirazi, SS; Zike, WL | 1 |
| Dimitriades, M; Midoulas, N; Panopoulos, C; Papadimitriou, GC; Razis, DV | 1 |
| Euler-Rolle, J; Kerstan, E; Tuchmann, A | 1 |
| Bergreen, PW; Buell, GV; Saiers, JH; Saiki, JH | 1 |
| Denck, H | 1 |
| Betzler, M; Herfarth, C; Schlag, P; Schreml, W | 1 |
| Costanzi, J; Hoogstraten, B; Kennedy, A; Maloney, TR; Palmer, RL; Rivkin, S; Samal, B; Smith, F; Thigpen, T; Tranum, B; Tucker, WG; Vaughn, CB; Wilson, H | 1 |
| Alexander, JA; Wheeler, GP | 1 |
| Mascia, V; Massidda, B; Pellegrini, A | 1 |
| Collis, CH | 1 |
| Bertino, JR; Bobrow, SN; Boston, B; Kennealey, GT; Knobf, MK; Lawrence, R; Mitchell, MS; Pezzimenti, JF | 1 |
| Boberić, J; Bugarski, M; Dilparić, S; Milosavljević, A; Naumović, P; Tomin, R; Vuletić, L | 1 |
| Kleckow, M; Mattern, J; Vogt-Moykopf, I; Volm, M; Wayss, K | 1 |
| Leslie, RA; MacDonell, LA; Potter, PE | 1 |
| Hartmann, D; Obrecht, JP | 1 |
| Beller, FK; Möhlen, KH | 1 |
| Curry, SL; Gallagher, HS; Smith, JP | 1 |
| Block, GE; DeSombre, E; Ellis, RS; Jensen, E | 1 |
| Sveinsson, T; von der Maase, H | 1 |
| von der Maase, H | 3 |
| Calabresi, P; DeNucci, T; Dexter, DL; Heppner, GH; Miller, FR | 1 |
| Mazloumi, B; Missmahl, HP; Weber, W | 1 |
| Braunschweiger, PG; Schiffer, LM; Stragand, JJ | 1 |
| Brown, I; Ward, HW | 1 |
| Goldin, A | 1 |
| de Loecker, W; van der Schueren, G | 1 |
| Bornovolokova, GA; Demidov, VP; Ol'shanskii, VO; Stiop, LD; Volkova, MA | 1 |
| Bates, IS; Brinkley, D; Edelstyn, GA; MacRae, KD; Spittle, H; Wheeler, T | 1 |
| Block, NL; Camuzzi, F; Claflin, A; Politano, VA; Stover, B; Troner, M | 1 |
| Gatzemeier, U; Jüngst, G; Wagner, G | 1 |
| Hayward, JL; Knight, RK; Rubens, RD | 1 |
| Marsh, JC | 1 |
| Cohen, D; Grover, NB; Weiss, DW; Yron, I | 1 |
| Bergsagel, DE | 2 |
| Kuritzky, A; Mintz, U | 1 |
| Scherf, HR; Schmähl, D | 1 |
| Tormey, DC; Waalkes, TP | 1 |
| Gang, M; Garibjanian, BT; Goldin, A; Johnson, RK; Kline, I; Vadlamudi, S; Venditti, JM | 1 |
| Gajcy, H | 1 |
| Berry, RJ; Laing, AH; Wells, J | 1 |
| Dubois, JB; Serrou, B | 1 |
| Birbraer, VM; Il'inskaia, EG; Pankov, AK; Sidorenko, IuS | 1 |
| Carbone, PP | 3 |
| Karrer, K; Pridun, N; Zwintz, E | 3 |
| Cooke, D; De Rose, G; Wilcox, LD | 1 |
| Firstater, M; Itzicovitch, L; Meshorer, A | 1 |
| Canellos, GP; Chabner, BA; DeVita, VT; Hubbard, SP; Young, RC | 1 |
| Young, RC | 3 |
| Birbraer, VM; Bordiushkov, IuN; Il'inskaia, EG; Pankov, AK; Sidorenko, IuS | 1 |
| Rees, RB | 1 |
| Bertino, JR; Gupta, VS; Lindquist, CA; Sawicki, WL | 1 |
| Bull, JM; Ingle, JN; Simon, RM; Tormey, DC | 1 |
| Balcerzak, SP; Bearden, JD; Coltman, CA; Costanzi, JJ; Lane, M; Moon, TE; Morrison, FS; Rivkin, SE; Saiki, JH; Spigel, SC | 1 |
| Diemath, HE | 1 |
| Graze, PR; Haskell, CM; Korenman, SG; Sparks, FC | 1 |
| Goh, SH; Léjohn, HB | 1 |
| Jensen, TS; Ogaard, S | 1 |
| Kane, RD; Paulson, DF; Stocks, LH | 1 |
| Auclerc, G; Cerbonnet, G; Jacquillat, Cl | 1 |
| Grünberger, W; Pantucek, F | 1 |
| Arthur, K; Banks, AJ; Bond, WH; Brown, I; Chowdhury, MS; Freeman, WE; Holme, GM; Jones, WG; Newsholme, GA; Ward, HW | 1 |
| Cheng, FC; Lee, CM; Ong, GB | 1 |
| Nystrom, JS; Viola, MV | 1 |
| Hugo, K; Knipper, W; Weber, W | 1 |
| Bonadonna, G; Rossi, A; Veronesi, U | 1 |
| Hoffbrand, AV; Hooton, JW | 2 |
| Biran, S; Brufman, G; Hochman, A; Krasnokuki, D | 1 |
| Fassio, D; Giovanelli, E; Neretto, G | 1 |
| Carter, DC; Jamieson, GG | 1 |
| Daoud, D; Fox, N; Tan, J | 1 |
| Medina, D; Shepherd, F | 1 |
| Flubacher, P; Hartmann, D; Meier, V; Obrecht, JP | 1 |
| Smolyanskaya, AZ | 1 |
| Brahm, M; Mouridsen, HT; Palshof, T; Rahbek, I | 1 |
| Broder, LE; Carbone, PP | 1 |
| West, JH | 1 |
| Dombernowsky, P; Nissen, NI | 1 |
| Blau, HJ | 1 |
| Bonnet, JD; Braine, H; Costanzi, JJ; George, SL; Hoogstraten, B; Rivkin, SE; Samal, B; Thigpen, T | 1 |
| Schuppli, R | 3 |
| Riedler, L | 1 |
| Matthiessen, W; Pochhammer, KF | 1 |
| Barthel, E; Felsch, G; Siering, H | 1 |
| Abisatov, KhA; Khan, SV | 1 |
| King, JC; McRae, MP | 1 |
| Bartolucci, AA; Huguley, CM; Murphy, S; Smalley, RV | 1 |
| Barndt, J | 1 |
| Baumgartner, G | 1 |
| Morton, DL; Ramming, KP; Silver, HK; Sparks, FC; Wile, AG; Wolk, RW | 1 |
| Band, PR; Canellos, GP; Klaasen, DJ; Pocock, SJ; Sears, ME; Taylor, SG | 1 |
| Lowitz, BB | 1 |
| Dao, TL; Nemoto, T; Rosner, D | 1 |
| Kane, RD; Mickey, DD; Paulson, DF | 1 |
| Bulbrook, RD | 1 |
| Hutchison, DJ; Otter, GM; Schmid, FA; Stock, CC | 1 |
| Dalcq, JM; Derriks, R; Laurent, C; Mannes, P; Moens, R | 1 |
| Edelstyn, GA; MacRae, KD | 3 |
| Morley, AA; Trainor, KJ | 1 |
| Raevskiĭ, IG | 2 |
| Derriks, R; Laurent, C; Mannes, P; Moens, R | 1 |
| Band, PR; Carbone, PP | 1 |
| Israel, L | 2 |
| Heuson, JC | 1 |
| Siebner, H; Weber, W | 1 |
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| Abeloff, MD; Costanzi, JJ; Cruz, AB; Farrar, WB; Green, S; Jewell, WR; O'Sullivan, J; Osborne, CK; Rivkin, SE | 1 |
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| Adler, D; Helvie, M; Lichter, A; Merajver, S; Pierce, L | 1 |
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| Bertelli, G; Bruzzi, P; Del Mastro, L; Garrone, O; Guelfi, M; Pastorino, S; Rosso, R; Sertoli, MR; Venturini, M | 1 |
| Amadori, S; Bendandi, M; Falini, B; Gherlinzoni, F; Mandelli, F; Martelli, M; Martelli, MF; Pileri, SA; Sabattini, E; Tura, S; Zinzani, PL | 1 |
| Albanell, J; Baselga, J; Bellmunt, J; Bermejo, B; Carulla, J; Eres, N; Gallardo, E; Ribas, A; Solé-Calvo, LA; Vera, R; Vidal, R | 1 |
| Aust, JC; Bank, A; Canellos, GP; Carey, RW; Gottlieb, A; Holland, JF; Korzun, AH; Norton, L; Perloff, M; Perry, MC; Saleh, F; Silver, RT; Weiss, RB; Wood, WC | 1 |
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| Archimandritis, A; Bacoyiannis, C; Giannopoulos, A; Kalahanis, N; Karatzas, G; Kosmas, C; Kosmidis, P; Papachristodoulou, A; Papadimas, V; Polyzos, A; Sakelaropoulos, N; Tsavaris, N | 1 |
| Belpomme, D; Chollet, P; Delgado, M; di Palma, M; Fargeot, P; Fumoleau, P; Guerrin, J; Hill, C; Ithzaki, M; Le Mevel, B; Mathé, G; Metz, R; Misset, JL; Plagne, R | 1 |
| Maestri, A; Malacarne, P | 1 |
| Baldini, E; Bevilacqua, G; Collecchi, P; Conte, PF; Giannessi, PG; Naccarato, AG; Passoni, A | 1 |
| Carstensen, JM; Nordenskjöld, B; Rutqvist, LE; Skoog, L; Stål, O; Sullivan, S; Wingren, S | 1 |
| Bamberger, U; Boven, E; Feller, N; Jansen, WJ; Pinedo, HM; van der Wilt, CL | 1 |
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| DiPaola, RS; Kaufman, A; Mikhail, MM | 1 |
| Bassot, V; Brasnu, D; Laccourreye, L; Laccourreye, O; Naudo, P; Roux, FX | 1 |
| Davydov, MI; Ivshina, AV; Mkheidze, DM; Normantovich, VA; Polotskiĭ, BE | 1 |
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| Ganssauge, F; Plasswilm, L; Sauer, R; Seegenschmiedt, MH | 1 |
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| Dawson, NA; Diehl, LF; Phillips, ET; Rickles, NM; Solimando, DA; Weiss, RB | 1 |
| Bernier, J; Castiglione-Gertsch, M; Gelber, RD; Goldhirsch, A; Joseph, D; Roncadin, M; Wallgren, A | 1 |
| Bulian, D; Kreft, B; Kurth, S; Riemenschneider, T | 1 |
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| Stewart, A | 1 |
| Kasamatsu, T; Kawazoe, Y; Kohda, K | 1 |
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| Kohno, N; Kusunoki, M; Nakazawa, E; Nishiya, M | 1 |
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| Babini, L; Bendandi, M; Frezza, G; Gherlinzoni, F; Magagnoli, M; Merla, E; Salvucci, M; Tura, S; Zinzani, PL | 1 |
| Bonetti, A; Bonetti, F; Cetto, GL; Molino, A; Nortilli, R; Piubello, Q; Rodella, S; Sperotto, L; Turazza, M; Zaninelli, M | 1 |
| Castiglione-Gertsch, M; Cavalli, F; Coates, AS; Collins, J; Cortés-Funes, H; Forbes, JF; Galligioni, E; Gelber, RD; Goldhirsch, A; Gudgeon, A; Lindtner, J; Marini, G; Murray, S; Price, KN; Rudenstam, CM; Senn, HJ; Tattersall, MH | 1 |
| Gustafson, P | 1 |
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| Altman, DG; Parmar, MK; Stewart, LA | 1 |
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| Antonelli, G; Bonadonna, G; De Candis, D; Valagussa, P | 1 |
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| Barni, S; Facendola, G; Labianca, R; Luporini, G; Marini, G; Martignoni, G; Pirovano, M; Vaghi, M; Vinci, M; Zaniboni, A | 1 |
| Abbasciano, V; Nielsen, I; Sartori, S; Tassinari, D; Trevisani, L | 1 |
| Rees, GJ | 1 |
| Blomgren, H; Ragnhammar, P | 1 |
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| Arai, K; Iwasaki, Y; Kitamura, M | 2 |
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| Abe, O; Itoh, M; Nakamura, S; Nishio, T; Ohigashi, S; Sakurai, K | 1 |
| Ando, M; Fukunari, H; Gonda, T; Hojo, I; Ishida, H | 1 |
| Furukawa, H; Hiratsuka, M; Imaoka, S; Ishikawa, O; Iwanaga, T; Kabuto, T; Kameyama, M; Nakamori, S; Nakano, H; Ohigashi, H; Sasaki, Y; Tsuji, Y; Yasuda, T | 1 |
| Aschele, C; Grossi, F; Guglielmi, A; Sobrero, A; Tixi, L | 1 |
| Chernova, OB; Gilbert, C; Poupon, MF; Smith, KA; Stark, GR | 1 |
| Fine, S; Pater, J; Paterson, AH; Paul, NA; Pritchard, KI; Zee, B | 1 |
| Body, JJ | 1 |
| Colangelo, D; Colavito, P; Colucci, G; Coviello, M; Giotta, F; Maiello, E; Quaranta, M; Rella, C; Schittulli, F | 1 |
| Hilgenfeld, RU; Kreuser, ED; Streit, M; Thiel, E | 1 |
| Albertsson, M; Cwikiel, M; Eskilsson, J; Stavenow, L | 1 |
| Bertino, J; Casper, E; Christman, K; Colofiore, J; Kelsen, D; Martin, DS; Quan, V; Saltz, L; Schwartz, GK | 1 |
| DeGoeij, K; Mester, J; Sluyser, M | 1 |
| Becagli, P; Messori, A; Tendi, E; Trippoli, S | 1 |
| Bhargava, MK; Udayakumar, AM | 1 |
| Kramer, N; Leitner, SP; Michaelson, RA; Rosenstein, ED | 1 |
| Martus, P; Sauer, R | 1 |
| Blau, CA; Neff, T; Papayannopoulou, T | 1 |
| Eguchi, R; Hayashi, K; Ide, H; Nakamura, T | 1 |
| Agarwal, GN; Ahuja, RC; Ayyagari, S; Datta, NR; Kumar, S; Mali, HR | 1 |
| Facendola, G; Labianca, R; Luporini, G; Pessi, A; Pirovano, M | 1 |
| Thomssen, C | 1 |
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| Cuevas, MA; De Lena, M; Lacava, J; Leone, B; Machiavelli, M; Paradiso, A; Perez, J; Rabinovich, M; Rodriquez, R; Romero, A; Sapia, MG; Simone, G; Vallejo, C | 1 |
| Casaretti, R; Catalano, G; Comella, G; Comella, P; Frasci, G; Ianniello, GP; Lorusso, V; Montella, M; Nicollela, D; Palmieri, G; Perna, M | 1 |
| Hashimoto, M; Kawasaki, T; Kikuyama, M; Kobayashi, Y; Murohisa, G; Shimizu, E; Souda, K; Suzuki, F; Tsugiki, M; Yoshimi, T | 1 |
| Bertolissi, A; Cartei, G; Cioschi, B; Marsilio, P; Rizzi, V; Tabaro, G | 1 |
| Cunningham, D; Findlay, M; Harper, P; Hickish, T; Hill, A; Hughes, M; Iveson, T; Joffe, JK; Mansi, J; Meehan, M; Nicolson, M; Norman, A; O'Brien, M; Oates, J; Scarffe, JH; Underhill, C; Wardley, A; Watson, M; Webb, A | 1 |
| Aschele, C; Bertino, JR; Sobrero, AF | 1 |
| Katai, H; Maruyama, K; Noda, N; Ono, H; Sano, T; Sasako, M; Shirao, K | 1 |
| Bovbjerg, DH; McClary, KA; Montgomery, GH | 1 |
| Birch, R; Greco, FA; Hainsworth, JD; Hopkins, LG; Jolivet, J | 1 |
| Imamura, M; Maetani, S; Nishitai, R; Onodera, H; Shimizu, K | 1 |
| Deeb, LS; Shabb, NS; Shamseddine, AI; Uthman, SM; Yamout, BI | 1 |
| Amadori, A; Amadori, D; Amaducci, L; Giunchi, DC; Maltoni, R; Nanni, O; Saragoni, A; Silvestrini, R; Vio, A; Volpi, A | 1 |
| Fehm, T; Jäger, W; Katalinic, A; Maimonis, P; Teramoto, Y; Weitz, S | 1 |
| Badellino, F; Canavese, G; Catturich, A; Gipponi, M; Repetto, L; Sertoli, MR; Tomei, D; Vecchio, C | 1 |
| Kinsella, AR; Pickard, M; Smith, D | 1 |
| Kitao, Y; Miyagaki, T; Nakamura, T; Yamamoto, K; Yasuoka, R | 1 |
| Bünemann, H; Heilmann, HP; Janik, I; Willers, H; Würschmidt, F | 1 |
| De Filippis, S; Lalli, A; Nuzzo, A; Recchia, F; Torchio, P | 1 |
| Baldini, E; Conte, P; da Prato, M; Evangelista, G; Giannessi, P; Lencioni, M; Meucci, C; Roncella, M; Spinelli, C; Tibaldi, C | 1 |
| Aihara, K; Shimura, T; Teramoto, A | 1 |
| Del Mastro, L; Rosso, R; Sertoli, MR; Venturini, M | 1 |
| Semiglazov, VF | 1 |
| Cağatay, T; Celikoğlu, F; Celikoğlu, SI; Demirci, S; Karayel, T | 1 |
| Comley, M; Engels, K; Fox, SB; Gatter, KC; Harris, AL; Turley, H; Whitehouse, RM | 1 |
| Malmström, P; Sjövall, MP | 1 |
| Ackland, S; Bishop, JF; Dewar, J; Goldstein, D; Gurney, H; Kennedy, I; Levi, J; Olver, IN; Stephenson, J; Tattersall, MH; Toner, GC; Walpole, E | 1 |
| Inaba, M | 1 |
| Baccarani, M; Barillari, G; Cerno, M; Damiani, D; Fanin, R; Geromin, A; Infanti, L; Rinaldi, C; Savignano, C; Silvestri, F; Zaja, F | 1 |
| Allegra, CJ; Byrne, MJ; Castiglione-Gertsch, M; Cortés-Funes, H; Gelber, RD; Goldhirsch, A; Golouh, R; Gusterson, BA; Johnston, PG; Lindtner, J; Pestalozzi, BC; Peterson, HF; Rudenstam, CM; Simmoncini, E; Trihia, H | 1 |
| Achard, JL; Assier, I; Bay, JO; Charrier, S; Chollet, P; Cure, H; Dauplat, J; De Latour, M; Feillel, V; Ferrière, JP; Van Praagh, I | 1 |
| Blomqvist, C; Elomaa, I; Mäkelä, P; Saarto, T; Sarna, S; Välimäki, M | 1 |
| Abu-Zahra, H; Armitage, GR; Bowman, D; Boyd, N; Bramwell, VH; Buckman, RA; Fine, S; Knowling, M; Levine, MN; Norris, BD; Paterson, AH; Paul, NA; Perrault, D; Poljicak, M; Pritchard, KI; Ragaz, J; Shepherd, LE; Verma, S; Walde, PL; Warr, D; Weizel, H; Zee, B | 1 |
| Bajorin, DF; Heineman, M; Hilton, S; Hirsch, J; Kelly, WK; Mazumdar, M; McCaffrey, JA; Sadan, S; Scher, HI | 1 |
| Barrett, JC; Dunn, SE; Hardman, RA; Kari, FW | 1 |
| Kamm, YL; Punt, CJ; Wagener, DJ | 1 |
| Castiglione, M; Cavalli, F; Jungi, WF; Leyvraz, S; Maibach, R; Obrecht, JP; Schildknecht, O; Senn, HJ; Siegenthaler, P | 1 |
| Croisy, A; Jullien, P; Lawrence, DA; Nocentini, S; Raynal, S | 1 |
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| Köhne, CH; Schmoll, HJ; Schöffski, P; Wilke, H | 1 |
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| Grillot, DA; Nuñez, G; Simonian, PL | 1 |
| Cramer, MB; Hahne, WF; Kasimis, BS; Schulman, P; Stewart, WH; Tapazoglou, E | 1 |
| Jansen, G; Peters, GJ; Pinedo, HM; Telleman, F; van der Wilt, CL; van Triest, B | 1 |
| el-Yazigi, A; Ezzat, A | 1 |
| Adami, F; Banzi, C; Criscuolo, M; Frassoldati, A; Piccinini, L; Silingardi, V | 1 |
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| Inaji, H; Koyama, H; Motomura, K; Noguchi, S | 1 |
| Oberhoff, C; Schindler, AE; Tauchert, AM; Winkler, UH | 1 |
| Hata, K; Kaganoi, J; Nanbu, H; Nishitai, R; Ohsumi, K; Tokunaga, Y | 1 |
| Athanassiades, P; Athanassiadou, P; Mavrikakis, M; Petrakakou, E; Zerva, C | 1 |
| Johnson, JT; Myers, EN; Pitman, KT | 1 |
| Brenner, B; Fenig, E; Hana, MB; Katz, A; Rakovsky, E; Sulkes, A | 1 |
| Arcangeli, G; Biggio, A; Cruciani, E; Danesi, DT; Giacobini, S; Mecozzi, A; Orefici, F; Pannunzio, E; Saracino, B | 1 |
| Dees, EC; Shulman, LN; Smith, BL; Souba, WW | 1 |
| Codes, M; Dugue, A; Garcia, E; Iglesias, L; Moreno, JA; Murillo, E; Torrija, E; Virizuela, JA | 1 |
| Fujimori, Y; Iki, K; Imai, H; Iwamoto, S; Kawasaki, S; Kimoto, M; Kubozoe, T; Murakami, T; Mure, T; Onuma, E; Tadaoka, Y; Takeo, T; Tsunoda, T; Yamamoto, Y; Yoshida, K | 1 |
| Berns, T; Harstrick, A; Hiddemann, W; Köhne, CH; Preusser, P; Schmoll, HJ; Seeber, S; Strumberg, D; Wilke, H | 1 |
| Brandys, A; Gliński, B; Krzemieniecki, K; Mitus, J; Pawlicki, M; Reinfuss, M; Skołyszewski, J; Stelmach, A; Walasek, T; Zuchowska, B | 1 |
| Braverman, AS; Dauphin, S; el Tamer, M; Katz, S; Sohn, C; Wait, R | 1 |
| Ackland, S; Bishop, JF; Dewar, J; Goldstein, D; Gurney, H; Kennedy, I; Levi, J; Olver, I; Stephenson, J; Tattersall, MH; Toner, G; Walpole, E | 1 |
| Agresti, R; Bertuzzi, A; Bonadonna, G; Capri, G; Gianni, L; Grasselli, G; Greco, M; Lombardi, F; Moliterni, A; Pilotti, S; Piotti, P; Salvadori, B; Tarenzi, E; Terenziani, M; Valagussa, P | 1 |
| Audretsch, W; Carl, UM; Gripp, S; Hartmann, KA; Kolotas, C; Muskalla, K; Rezai, M; Schmitt, G; Schnabel, T; Waap, I; Zamboglou, N | 1 |
| Fujita, M; Furukawa, H; Hiratsuka, M; Imaoka, S; Ishikawa, O; Kabuto, T; Kameyama, M; Kuroda, C; Nakamori, S; Nakano, H; Ohigashi, H; Sasaki, Y; Yasuda, T | 1 |
| Ebuchi, M; Endo, M; Maruyama, M; Sugano, N; Takamatsu, S; Yuasa, Y | 1 |
| Imoto, S | 1 |
| Abramson, N; Atkins, JN; Bryant, J; DeCillis, A; Deschenes, L; Dignam, J; Dimitrov, NV; Emir, B; Fisher, B; Margolese, RG; Shibata, H; Wickerham, DL; Wolmark, N | 1 |
| Andersson, M; Bach, F; Gadeberg, CC; Hansen, PS; Jensen, MB; Kjaer, M; Mouridsen, HT; Overgaard, J; Overgaard, M; Rose, C; Zedeler, K | 1 |
| Annegers, JF; Buzdar, AU; Dhingra, K; Frankowski, RF; Frye, DK; Hortobagyi, GN; Kinney, AY; Sahin, A; Vernon, SW | 1 |
| Agostara, B; Amoroso, D; Boccardo, F; Farris, A; Gallo, L; Mesiti, M; Pacini, P; Perrotta, A; Rubagotti, A; Sismondi, P; Villa, E | 1 |
| Barnes, DM; Dublin, EA; Miles, DW; Rubens, RD; Smith, P | 1 |
| Back, M; Delaney, G; Denham, J; Graham, P; Hamilton, C; Morgan, G; O'Brien, P; Yuile, P | 1 |
| Bonadonna, G; Brambilla, C; Ferrari, L; Moliterni, A; Terenziani, M; Valagussa, P; Zambetti, M | 1 |
| Ashley, S; Baum, M; Ebbs, S; Ellis, P; McKinna, J; Sacks, N; Smith, I; Walsh, G | 1 |
| Emanuel, EJ; Patterson, WB | 1 |
| Coates, AS; Colleoni, M; Gelber, RD; Goldhirsch, A | 1 |
| Kamei, M; Kawabata, H; Matsuda, K; Nishioka, M; Sasahara, K; Uchida, Y | 1 |
| Bokemeyer, C; Dörken, B; Harstrick, A; Hiddemann, W; Köhne, CH; Schmoll, HJ; Schöffski, P; Wilke, H | 1 |
| Evans, WE; Hon, YY | 1 |
| Becagli, P; Messori, A; Trippoli, S | 1 |
| Brüster, HT; Kuntz, BM; Schöttler, B | 1 |
| Arcangeli, G; Comandini, E; D'Angelo, L; D'Aprile, M; Giovinazzo, G; Lopez, M; Mauri, M; Micheli, A; Scala, T; Tersigni, R | 1 |
| Bitran, JD; Grad, G; Grinblatt, DL; Laport, GF; Williams, SF | 1 |
| Baccarani, M; Cerno, M; Damiani, D; Fanin, R; Geromin, A; Infanti, L; Rinaldi, C; Savignano, C; Silvestri, F; Sperotto, A; Stocchi, R | 1 |
| Albanell, J; Bellmunt, J; Bermejo, B; Bodi, R; Gallardo, E; Ribas, A; Solé-Calvo, LA; Vera, R | 1 |
| Watanabe, T | 2 |
| Tsukuda, M | 1 |
| Sakata, Y; Tsushima, K | 1 |
| Bourstyn, E; de Cremoux, P; de Roquancourt, A; Degeorges, A; Espie, M; Extra, JM; Marty, M; Soussi, T | 1 |
| Acuña, JM; Acuña, LA; Amato, S; Barbieri, MR; Cuevas, MA; DeLena, M; Dominguez, ME; Lacava, JA; Langhi, MJ; Leone, BA; Lorusso, V; Machiavelli, MR; Ortiz, EH; Perez, JE; Rodriguez, R; Romero, AO; Sabatini, CL; Salvadori, MA; Vallejo, CT | 1 |
| Akamine, T; Hanada, N; Hiraoka, T; Hongo, H; Kitamura, N; Kondo, K; Mori, T; Tabira, Y; Toyota, N; Yoshioka, M | 1 |
| Araki, S; Asakura, R; Hojo, K; Itoh, A; Kawahara, M; Konishi, T; Nouchi, T; Takeda, Y; Teruya, M | 1 |
| Iki, K; Iwamoto, S; Kawasaki, S; Kimoto, M; Kubozoe, T; Majima, T; Mure, T; Onuma, E; Tadaoka, Y; Tsunoda, T; Yamamoto, Y; Yoshida, K | 1 |
| Allegra, CJ; Chabner, BA; Chu, E; Fidias, P; Grem, JL; Grossbard, ML; Johnston, PG; Takimoto, CH | 1 |
| Castiglione-Gertsch, M; Coates, AS; Colleoni, M; Gelber, RD; Goldhirsch, A | 2 |
| Albertini, P; Ascani, S; Bendandi, M; Buzzi, M; Gherlinzoni, F; Magagnoli, M; Pileri, S; Sabattini, E; Tura, S; Zinzani, PL | 1 |
| Cartei, G; Iop, A; Isaia, A | 1 |
| Kinsella, AR; Smith, D | 1 |
| Barbat, A; Dussaulx, E; Lesuffleur, T; Muleris, M; Vasile-Pandrea, I; Violette, S; Zweibaum, A | 1 |
| Abeloff, MD; Cummings, FJ; Falkson, G; Gelman, RS; Osborne, CK; Pandya, KJ; Sledge, GW; Tormey, D | 1 |
| Ardalan, B; Franceschi, D; Jaime, M; Luis, R | 1 |
| Agrawal, S; Bianco, AR; Bianco, R; Caputo, R; Ciardiello, F; Damiano, V; Jiang, Z; Pepe, S; Pomatico, G; Tortora, G | 1 |
| Hart, G; Koning, C | 1 |
| Bellantone, R; Cefaro, GA; Crucitti, F; Lombardi, CP; Minelli, S; Nardone, L; Raffaelli, M; Rossi, S | 1 |
| Heidemann, E | 1 |
| Castiglione-Gertsch, M; Coates, A; Collins, J; Gelber, RD; Goldhirsch, A; Gudgeon, A; Hacking, A; Isley, M; Lindtner, J; Rudenstam, CM; Senn, HJ; Tattersall, M | 1 |
| Fridrik, M; Gnant, M; Hausmaninger, H; Jakesz, R; Kolb, R; Kubista, E; Samonigg, H; Sevelda, P; Steger, G; Steindorfer, P; Stierer, M; Tschurtschenthaler, B | 1 |
| Cao, Z; Peng, Z; Zhang, D | 1 |
| Dreger, P; Glass, B; Kuse, R; Löffler, H; Schmitz, N; Schoch, R; Sonnen, R; Uharek, L; von Neuhoff, N | 1 |
| Cafaggi, S; Esposito, M; Pastrone, I; Pellecchia, C; Vannozzi, MO; Viale, M | 1 |
| Aguggini, S; Alquati, P; Berruti, A; Bersiga, A; Bertoli, A; Betri, E; Bolsi, G; Bottini, A; Brizzi, MP; Brunelli, A; Cirillo, F; Di Marco, B; Dogliotti, L; Filippini, L; Tampellini, M | 1 |
| Abeloff, MD; Cella, D; Citron, ML; Fairclough, DL; Fetting, JH; Gray, R; Grove-Conrad, M; Henderson, IC; Margolin, KA; Osborne, CK; Pandya, K; Robert, N; Smith, TJ | 1 |
| Das Gupta, TK; Hieken, TJ; Marler, KC; McDermott, JH; Mehta, RR; Patel, MK; Wild, LD | 1 |
| Ganesan, TS; Harris, AL; Isaacs, R; Koukourakis, MI; O'Byrne, KJ; Salisbury, AJ; Saunders, MP; Talbot, DC; Taylor, M; Varcoe, S | 1 |
| Botto, F; Ghio, E; Neri, E; Pensa, F; Pronzato, P; Tognoni, A; Vaira, F; Vigani, A | 1 |
| Cole, BF; Gelber, RD; Glasziou, PP; Hilden, J; Simes, RJ | 1 |
| Bonavida, B; Mizutani, Y; Yoshida, O | 1 |
| Akiyama, T; Kita, I; Kosaka, T; Nakano, Y; Saito, H; Sugaya, J; Takashima, S; Tomita, F; Ueshige, N | 1 |
| Deguchi, T; Kawada, Y; Kuriyama, M; Nakano, M; Shinoda, I; Takahashi, Y; Takeuchi, T; Yamamoto, N; Yasuda, M; Yoh, M | 2 |
| Ebuchi, M; Irie, T; Maruyama, M; Nagahama, T; Sugano, N; Yoshida, T | 1 |
| Abraham, J; Barrett-Lee, P; Faris, M | 1 |
| Abu-Zahra, H; Arnold, A; Bowman, D; Bramwell, VH; Burnell, M; Findlay, B; Levine, MN; MacKenzie, R; Myles, J; Norris, BD; Ottaway, J; Pritchard, KI; Robert, J; Shepherd, LE; Tu, D; Vandenberg, T; Warr, D; Williams, CK | 1 |
| Castiglione, M; Cavalli, F; Coates, A; Collins, J; Crivellari, D; Fey, M; Gelber, RD; Goldhirsch, A; Lindtner, J; O'Neill, A; Pagani, O; Price, K; Rudenstam, CM; Senn, HJ; Simoncini, E; Thürlimann, B | 1 |
| Boyages, J; Langlands, A | 1 |
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| Cunningham, D; Hill, ME | 1 |
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| Chen, IH; Chen, JS; Liao, CT; Su, CL; Wang, CH; Wang, HM | 1 |
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| Allen, BJ; Aslani, A; Levi, JA; Pavlakis, N; Smith, RC | 1 |
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| Cowley, L; Heyman, B; Milner, SJ; Stanton, M | 1 |
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| Bernhard, J; Bonetti, M; Castiglione-Gertsch, M; Cavalli, F; Coates, AS; Collins, J; Cortes-Funes, H; Crivellari, D; Fey, M; Forbes, J; Gelber, RD; Goldhirsch, A; Gudgeon, A; Hürny, C; Lindtner, J; Price, KN; Rudenstam, CM; Senn, HJ; Simoncini, E; Thürlimann, B; Veronesi, A | 1 |
| Song, S; Tang, Z; Xu, J | 1 |
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| Amir, C; Arthur, DW; Bear, HD; Friedman, RB; Hackney, MH; Kachnic, LA; Lawrence, W; Schmidt-Ullrich, RK; Smith, TJ; Wazer, DE | 1 |
| Bastert, G; Bauer, W; Bojar, H; Christmann, D; Dunst, J; Sauerbrei, W; Schmoor, C; Schumacher, M; Tümmers, G; Unbehaun, V | 1 |
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| Bonnefoy-Berard, N; Ferraro, C; Prigent, AF; Quemeneur, L; Revillard, JP; Taverne, C | 1 |
| Kajdaniuk, D; Marek, B | 1 |
| Chen, CM; Cheng, SH; Hsieh, CI; Huang, AT; Liu, MC; Liu, TW; Tsou, MH | 1 |
| Chang, J | 1 |
| Blohmer, J; Breitbach, P; Elling, D; Heinrich, J; Köhler, U; Kohls, A; Krocker, J; Kümmel, S; Lichtenegger, W; Quass, J | 1 |
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| Allegra, CJ; Chabner, BA; Chu, E; Grem, JL; Johnston, PG; Multani, P; Ryan, D; Takimoto, CH | 1 |
| Chen, J; Jiang, S; Li, J | 1 |
| Boiocchi, M; Crivellari, D; Toffoli, G; Veronesi, A | 1 |
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| Hoffmann, O; Oberhoff, C; Schindler, AE; Winkler, UH | 1 |
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| Arzumanov, AS; Barash, NIu; Bozhok, AA; Brezhneva, TV; Golubëva, OM; Ivanov, VG; Ivanova, OA; Migmanova, NSh; Orlov, AA; Paltuev, RM; Popova, PT; Seleznev, IK; Semiglazov, VF; Topuzov, EE | 1 |
| Angiona, S; Canaletti, R; Cavicchi, F; Contu, A; Di Costanzo, F; Gasperoni, S; Luppi, G; Olmeo, N; Pucci, F; Rodinò, C; Sdrobolini, A; Zironi, S | 1 |
| Kohn, KW; O'Connor, PM; Orr, MS | 1 |
| Bos, AM; de Graaf, H; de Vries, EG; Piersma, H; Willemse, PH | 1 |
| Aebi, S; Castiglione-Gertsch, M; Coates, AS; Collins, J; Cortes-Funes, H; Crivellari, D; Gelber, RD; Gelber, S; Goldhirsch, A; Lindtner, J; Rudenstam, CM; Simoncini, E; Thürlimann, B; Werner, ID | 1 |
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| Aldrighetti, D; Amoroso, D; Boccardo, F; Bolognesi, A; Distante, V; Farris, A; Genta, F; Giai, M; Mesiti, M; Pacini, P; Romeo, D; Rubagotti, A; Sismondi, P | 1 |
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| Bonadonna, G; Cipriani, S; Daidone, MG; Luisi, A; Silvestrini, R; Valagussa, P; Zambetti, M | 1 |
| Ragaz, J; Spinelli, JJ | 1 |
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| Bergh, J; Blomqvist, C; Hakamies-Blomqvist, L; Luoma, M; Malmström, P; Mjaaland, I; Mouridsen, H; Ostenstad, B; Ottosson-Lönn, S; Pluzanska, A; Sjödin, M; Sjöström, J | 1 |
| Ackland, S; Atkinson, C; Bonaventura, A; Dady, P; Denham, J; Hamilton, C; Joseph, D; Lamb, D; O'Brien, P; Spry, N; Stewart, J | 1 |
| Aguggini, S; Alquati, P; Berruti, A; Bersiga, A; Bertoli, G; Betri, E; Bolsi, G; Bottini, A; Brizzi, MP; Brunelli, A; Cirillo, F; DiMarco, B; Dogliotti, L; Filippini, L; Gorzegno, G | 1 |
| Han, Q; Shen, K; Shen, Z | 1 |
| Ando, J; Fujisaki, M; Ikeda, T; Imoto, S; Kobayashi, H; Kojima, M; Oka, S; Tamura, H; Wada, N | 1 |
| Bockenheimer, J; Eichler, HG; Klein, N; Mader, RM; Müller, M; Steger, GG; Zellenberg, U | 1 |
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| Amadori, D; Becciolini, A; Catalano, G; Gambi, A; Giunchi, DC; Marangolo, M; Nanni, O; Pacini, P; Perroni, D; Ravaioli, A; Rossi, A; Scarpi, E; Tienghi, A; Volpi, A | 1 |
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| Fukuda, K; Kim, YH; Kitano, H; Kokufu, I; Taniguchi, H; Yamada, K; Yamamoto, M; Yano, T | 1 |
| Dohna, CL; Engeland, K; Haugwitz, U; Krause, K; Mössner, J; Reinhard, W; Wasner, M | 1 |
| Bredart, A; Colleoni, M; Goldhirsch, A; Mandala, M; Peruzzotti, G; Robertson, C | 1 |
| Cunningham, D; Hill, ME; Norman, A; Ross, PJ | 1 |
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| Pletnev, SD | 1 |
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| Coldman, AJ; Murray, JM | 1 |
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| Arnoldi, E; Aschele, C; Barni, S; Bruzzi, P; Caroti, C; Cortesi, E; Frassineti, GL; Frontini, L; Gallo, L; Giuliani, R; Grossi, F; Guglielmi, A; Labianca, R; Lanfranco, C; Pessi, MA; Piazza, E; Ravaioli, A; Sobrero, A; Turci, D; Zaniboni, A | 1 |
| Jerkeman, M; Longo, G; Messori, A; Rigacci, L; Trippoli, S; Vaiani, M | 1 |
| Abramson, N; Anderson, S; Atkins, JN; Dimitrov, NV; Farrar, WB; Fisher, B; Fisher, ER; Kardinal, CG; Margolese, RG; Merajver, S; Romond, EH; Shibata, HR; Tan-Chiu, E; Wickerham, DL; Wolmark, N | 1 |
| Ackland, SP; Anton, A; Breitbach, GP; Colajori, E; Delfino, C; Efremidis, A; Ezzat, A; Fittipaldo, A; Kolaric, K; Lopez, M; Tursi, JM; Viaro, D | 1 |
| Alzieu, L; Berlie, J; Delozier, T; Fargeot, P; Lacour, J; Laplanche, A; Luboinski, M; Veyret, C | 1 |
| Biganzoli, E; Bonadonna, G; Boracchi, P; Casalini, P; Cascinelli, N; Colnaghi, MI; Gianni, L; Marubini, E; Ménard, S; Pilotti, S; Tomasic, G; Valagussa, P | 1 |
| Bernardo, MV; Harrington, DP | 1 |
| Arvelo, F; Bras-Gonçalves, RA; Coquelle, A; De Pinieux, G; Dutrillaux, B; Formento, JL; Lesuffleur, T; Milano, G; Pandrea, I; Pocard, M; Poirson-Bichat, F; Poupon, MF; Ronco, G; Villa, P | 1 |
| Allred, DC; Dressler, LG; Gray, R; Hatfield, AK; Martino, S; Page, DL; Robert, NJ; Wood, WC | 1 |
| Costa, A; Daidone, MG; Dellapasqua, S; Lacava, J; Lena, MD; Leone, B; Paradiso, A; Simone, G; Vallejo, C | 1 |
| Awazu, S; Fuwa, T; Horie, T; Itakura, Y | 1 |
| Biganzoli, E; Bonoldi, E; Boracchi, P; Fanelli, M; Gasparini, G; Morabito, A | 1 |
| Foekens, JA; Klijn, JG; Look, MP; Martin, PM; Romain, S | 1 |
| Antman, KH | 1 |
| Aschele, C; Caroti, C; Cirillo, M; Cortesi, E; Frassineti, GL; Gallo, L; Grossi, F; Guglielmi, A; Labianca, R; Pessi, MA; Ravaioli, A; Recaldin, E; Sobrero, A; Testore, P; Turci, D | 1 |
| Brown, RS; Burcombe, RJ; Gaze, MN; Osborne, ME | 1 |
| Blomqvist, C; Joensuu, H; Poikonen, P | 1 |
| Gao, R; King, ME; Mori, M; Nail, LM; Schwartz, AL | 1 |
| Chen, IH; Chen, JS; Liaw, CT; Ng, SH; Wang, CH; Wang, HM; Yang, TS | 1 |
| Aravantinos, G; Bafaloukos, D; Dimopoulos, AM; Ekonomopoulos, T; Fountzilas, G; Kalofonos, H; Nicolaides, C; Papadimitriou, C; Pavlidis, N; Skarlos, D; Stathopoulos, G | 1 |
| Delitheos, A; Miligkos, V; Papamichael, K; Tiligada, E; Ypsilantis, E | 1 |
| Bittner, C; Feyerabend, T; Peters, SO; Raap, M; Remmert, S; Robins, IH; Sieg, P; Sommer, K; Wiedemann, GJ | 1 |
| Cunningham, D; Hill, M; Norman, A; Tebbutt, NC | 1 |
| Mazeron, JJ; Noël, G | 2 |
| Bastert, G; Bojar, H; Sauerbrei, W; Schmoor, C; Schumacher, M | 1 |
| Bartier, WA; Cooper, WA; Delikatny, EJ; Rideout, DC | 1 |
| Frykholm, GJ; Glimelius, B; Påhlman, L | 1 |
| Berglund, G; Bolund, C; Nystedt, M; Rutquist, LE; Sjödén, PO | 1 |
| Brzozowska, A; Mazurkiewicz, M; Szatkowska, L | 1 |
| Bartholomeus, S; Beauduin, M; Beauvois, S; Closon-Dejardin, MT; Di Leo, A; Dolci, S; Dufrane, JP; Finet, C; Focan, C; Gobert, P; Kerger, J; Liebens, F; Lobelle, JP; Michel, J; Nogaret, JM; Paesmans, M; Piccart, MJ; Ries, F; Tagnon, A; Vindevoghel, A | 1 |
| Mayers, C; Panzarella, T; Tannock, IF | 1 |
| Graeff, H; Harbeck, N; Jänicke, F; Meisner, C; Prechtl, A; Schmitt, M; Selbmann, HK; Sweep, CG; Thomssen, C; Untch, M | 1 |
| Murakami, M | 1 |
| Amalan Stanley, V; Muralikrishnan, G; Sadasivan Pillai, K | 1 |
| Beauduin, M; de Greve, J; de Wasch, G; Focan, C; Lobelle, JP; Majois, F; Salamon, E; Tagnon, A; Tytgat, J; van Belle, S; Vandervellen, R; Vindevoghel , A | 1 |
| Coupek, P; Filip, S; Petera, J; Slampa, P; Soumarová, R; Zatloukal, P | 1 |
| Bruckner, HW; Evans, A; Kozuch, P; Petryk, M | 1 |
| Arzimanoglou, I; Chalkiadakis, G; Dimitrakakis, CE; Keramopoulos, A; Konstadoulakis, MM; Kymionis, GD; Leandros, E; Michalas, S | 1 |
| Borovik, R; Brenner, HJ; Brenner, J; Brufman, G; Catane, R; Chaitchik, S; Dale, A; Farbstein, H; Inbar, MJ; Rizel, S; Ron, IG; Shani, A; Wigler, N | 1 |
| Kajdaniuk, D; Kos-Kudla, B; Marek, B | 1 |
| Abzumanov, AS; Barash, NIu; Bozhok, AA; Ivanov, VG; Ivanova, OA; Migmanova, NSh; Nurgaziev, KSh; Popova, RT; Seleznev, IK; Semiglazov, VF; Topuzov, EE | 1 |
| Bornstein, R; Fruehauf, JP; Li, KT; McLaren, CE; Mehta, RS; Nguyen, KP; Parker, RJ; Yu, IR | 1 |
| Götze, HJ; Lerch, O; Teutenberg, T; Zinn, P | 1 |
| Arick, CL; Hutchins, LF | 1 |
| Beauduin, M; Closon-Dejardin, MT; Di Leo, A; Dolci, S; Focan, CH; Gancberg, D; Gobert, PH; Isola, J; Jarvinen, T; Larsimont, D; Lobelle, JP; Michel, J; Paesmans, M; Piccart, MJ; Ries, F; Rouas, G; Vindevoghel, A | 1 |
| Chan, CC; Nussenblatt, RB; Reed, GF; Robinson, MR; Sung, C; Tansey, G; Velez, G; Yuan, P | 1 |
| Shulman, LN | 1 |
| Castiglione-Gertsch, M; Coates, AS; Colleoni, M; Collins, J; Cortes-Funes, H; Fey, M; Gelber, RD; Gelber, S; Goldhirsch, A; Holmberg, SB; Lindtner, J; Murray, E; Price, K; Rudenstam, CM; Simoncini, E; Thürlimann, B | 1 |
| Leyland-Jones, B | 1 |
| Burstein, HJ; Winer, EP | 1 |
| Bell, D; Blum, J; Burger, HU; Jones, SE; Laws, S; Mauriac, L; Miles, D; Moiseyenko, V; Oshaughnessy, JA; Osterwalder, B; Rosso, R | 1 |
| Baba, H; Ebuchi, M; Kure, N; Maruyama, M; Nagahama, T; Toukairin, Y | 1 |
| Kawasaki, K; Kishibuchi, M; Nishi, T; Nishide, T; Ostapenko, V; Yagyu, T; Yamasaki, M; Yayoi, E | 1 |
| Furukawa, J; Katsumoto, Y; Maruyama, K; Maruyama, N; Nakaguchi, K; Nakamura, M; Okajima, S; Shingai, T; Sue, F; Yoshiwara, W | 1 |
| Hojo, T; Ikeda, T; Kawaguchi, M; Kitajima, M; Masamura, S; Matsui, A; Mitsui, Y; Miyabe, R; Takayama, S; Tokura, H | 1 |
| Baba, H; Ebuchi, M; Kure, N; Maruyama, M; Nagahama, T; Tokairin, Y; Yoshida, T | 1 |
| Munro, AJ | 1 |
| Bontenbal, M; Smorenburg, CH; Sparreboom, A; Verweij, J | 1 |
| Blomqvist, C; Elomaa, I; Mäkelä, P; Saarto, T; Välimäki, M; Vehmanen, L | 1 |
| Budd, GT; Carter, WB; Dickman, E; Ford, J; Fridman, M; Lawless, G; Lee, MW; Link, BK; Paul, D; Scott, S | 1 |
| Hinterleitner, T; Kerbl, R; Schwinger, W; Smolle Juettner, FM; Urban, C; Zotter, H | 1 |
| Beryt, M; Felber, M; Fritz, M; Hepp, H; Konecny, G; Lebeau, A; Lude, S; Pegram, M; Slamon, D; Untch, M | 1 |
| Hao, X; Sun, H; Zhu, Y | 1 |
| Clough, R; Fan, M; Hardenbergh, PH; Hernando, ML; Hollis, D; Lind, PA; Lucas, D; Marks, LB; Piepgrass, A; Prosnitz, LR | 1 |
| Huang, J; Wu, X; Zhang, J | 1 |
| Cao, Y; Liu, P; Qiao, X | 1 |
| Glück, S | 2 |
| Hathaway, B; Johnson, JT; Labriola, S; Myers, EN; Piccirillo, JF; Snyderman, CH; Wagner, RL | 1 |
| Barbareschi, M; Caffo, O; Dalla Palma, P; Galligioni, E; Kakudo, K; Mauri, F; Mori, I; Muscarà, M; Nakamura, M; Nakamura, Y; Sakurai, T; Yang, Q; Yoshimura, G | 1 |
| Ahn, SH; Bae, BN; Han, S; Kim, HJ; Kim, HY; Kim, KH; Kim, YD; Park, K | 1 |
| Jiang, Z; Liu, X; Song, S | 1 |
| Eguchi, T; Hirota, M; Ishii, M; Kanazumi, N; Kato, K; Kimura, J; Kobayashi, H; Suzuki, Y | 1 |
| Hausmaninger, H; Jakesz, R; Samonigg, H | 1 |
| Spooner, D; Stevens, A | 1 |
| Greywoode, GI; Griffiths, CL; Lewis, SM; Sugden, EM | 1 |
| Hu, Y; Lei, S; Mao, Y; Pei, F; Wei, Y; Zeng, J | 1 |
| O'Shaughnessy, J | 1 |
| Boku, N; Inoue, K; Kinoshita, T; Konishi, M; Nakagouri, T; Ohtsu, A; Ono, M; Sugitou, M; Takahashi, S; Yoshida, S | 1 |
| Boku, N; Hironaka, S; Mera, K; Muto, M; Nagashima, F; Ohtsu, A; Sano, Y; Tahara, M; Tajiri, H; Yoshida, M; Yoshida, S | 1 |
| Drouin, R; Lavoie, J | 1 |
| Branković-Magić, M; Janković, R; Nesković-Konstantinović, Z; Nikolić-Vukosavljević, D | 1 |
| Logothetis, CJ; Millikan, RE; Moore, DF; Siefker-Radtke, AO; Smith, TL; Tu, SM; Williams, D | 1 |
| Bengtsson, NO; Bergh, J; Blomqvist, C; Collan, J; Franssila, K; Malmström, P; Mjaaland, I; Saksela, E; Sjöström, J; Skiöld-Petterson, D; Valvere, V; von Boguslawski, K; Wist, E; Østenstad, B | 1 |
| Bengtsson, NO; Blomqvist, C; Malmström, P; Mjaaland, I; Ostenstadt, B; Reed, JC; Saksela, E; Sjöström, J; Takayama, S; Valvere, V; von Boguslawski, K; Wist, E | 1 |
| Lankester, KJ; Lawton, PA; Phillips, JE | 1 |
| Dillon, JJ; Fleming, GF; Hartman, AR | 1 |
| Bergauer, F; Dimpfl, T; Janni, W; Kaestner, R; Linka, F; Rack, B; Rjosk, D; Schindlbeck, C; Sommer, H; Strobl, B | 1 |
| Adlard, JW; Dodwell, DJ | 1 |
| Buyse, M; Di Leo, A | 1 |
| Love, RR | 1 |
| Hamaguchi, T; Haruyama, K; Matsumura, Y; Muro, K; Shimada, Y; Shirao, K; Sugano, K; Yamada, Y | 1 |
| Domoto, H; Miyakawa, K; Nanasawa, T; Shinoda, A; Tsuda, H | 1 |
| Illiger, HJ; Ost, E | 1 |
| Ioka, Z; Nakane, Y; Nakano, K; Osaka, Y; Sako, H; Takemura, N; Tanabe, S; Tsuchiya, K | 2 |
| Blackstock, AW; Case, D; Higgs, V; Melin, SA; Savage, P; Tomlinson, SK; White, DR | 1 |
| Ahigren, J; Baldursson, G; Bengtsson, NO; Blomqvist, C; Hakamies-Blomqvist, L; Hultborn, R; Luoma, ML; Malmström, P; Mjaaland, I; Mouridsen, H; Ostenstaad, B; Pluzanska, A; Sjöström, J; Valvere, V; Wist, E | 1 |
| Awada, A; Bartholomeus, S; Beauduin, M; Cardoso, F; Di Leo, A; Dolci, S; Ferreira Filho, AF; Focan, C; Michel, J; Paesmans, M; Piccart, MJ; Vindevoghel, A | 1 |
| Di Leo, A; Dolci, S; Gancberg, D; Isola, J; Jarvinen, T; Larsimont, D; Leroy, JY; Paesmans, M; Piccart, MJ; Rouas, G; Tanner, M | 1 |
| Azzabi, A; Batey, MA; Boddy, AV; Calvert, AH; Lind, MJ; Newell, DR; Wright, JG | 1 |
| Avigan, D; Elias, AD; Frei, E; Ibrahim, J; Joyce, R; McCauley, M; Reich, E; Richardson, P; Wheeler, C | 1 |
| Celik, I; Guc, D; Kars, A; Ruacan, S; Tekuzman, G | 1 |
| Hayakawa, H; Ishida, T; Kusaba, T | 1 |
| Brenin, DR; Brill, KL | 1 |
| Cianfrocca, M; Goldstein, LJ | 1 |
| Aguggini, S; Allevi, G; Alquati, P; Berruti, A; Bersiga, A; Bertoli, G; Betri, E; Bolsi, G; Bottini, A; Brizzi, MP; Brunelli, A; Dogliotti, L; Generali, D; Scaratti, L | 1 |
| Banerjee, D; Bertino, JR; Budak-Alpdogan, T; Capiaux, G; Gorlick, R; Mayer-Kuckuk, P | 1 |
| Bengtsson, NO; Blomqvist, C; Heikkilä, R; Malmström, P; Ostenstad, B; Paavonen, T; Saksela, E; Sjöström, J; Tynninen, O; Valvere, V; von Boguslawski, K; Wist, E | 1 |
| Bastert, G; Beyerle, C; Bonetti, M; Castiglione-Gertsch, M; Coates, AS; Colleoni, M; Collins, J; Crivellari, D; Gelber, RD; Goldhirsch, A; Holmberg, SB; Lindtner, J; Litman, HJ; Neumann, RL; Rudenstam, CM; Sauerbrei, W; Schmoor, C; Schumacher, M; Thürlimann, B | 1 |
| Eifrig, B; Hegewisch-Becker, S; Hossfeld, DK; Langer, F; Marx, G; Neuber, K | 1 |
| Carrara, HH; Silva, LM; Takahashi, CS | 1 |
| Descos, L; Freyer, G; Kraft, D; Ligneau, B; Trillet-Lenoir, V | 1 |
| Buzzi, F; Comella, P; Crucitta, E; De Cataldis, G; De Lucia, L; De Vita, F; Del Gaizo, F; Farris, A; Lannelli, A; Maiorino, L; Mancarella, S; Palmeri, S; Tafuto, S | 1 |
| Bella, M; Bisagni, G; Boni, C; Bruzzi, P; Camisa, R; Ceci, G; Cocconi, G; Di Blasio, B; Leonardi, F; Rondini, E; Savoldi, L | 1 |
| Leśniewski-Kmak, K; Szczylik, C; Zieliński, KW | 1 |
| Banzi, MC; Bertolini, M; Bondi, M; Del Rio, G; Federico, M; Menozzi, R; Piccinini, L; Valeriani, L; Zironi, S | 1 |
| Nishiyama, T; Takahasi, K; Tanikawa, T; Tomita, Y | 1 |
| Boogerd, W; Muller, MJ; Rodenhuis, S; Rosenbrand, RM; Schagen, SB; van Dam, FS; van Rhijn, D | 1 |
| Arnesson, LG; Emdin, SO; Fornander, T; Fredriksson, I; Frisell, J; Holmberg, L; Holmqvist, M; Liljegren, G; Palm-Sjövall, M | 1 |
| Doki, Y; Fujiwara, Y; Inoue, M; Monden, M; Shiozaki, H; Tamura, S; Tsujinaka, T; Yano, M; Yasuda, T | 1 |
| Isaac, N; Kirkbride, P; Lau, A; Mayers, C; Panzarella, T; Tannock, IF; Vallis, KA | 1 |
| Arcuri, MF; Corcione, L; Del Rio, P; Sivelli, R | 1 |
| Benito, E; Escobedo, A; Gumà, A; Moreno, A; Riu, F; Serra, JM | 1 |
| Jaffe, BM; Kahn, MJ; Weldon, CB | 1 |
| Arpino, G; Bianco, AR; Carlomagno, C; Catalano, G; Costanzo, R; De Laurentiis, M; De Placido, S; Ferrara, C; Lauria, R; Massarelli, E; Milano, A; Vernaglia Lombardi, A | 1 |
| Borovik, R; Brenner, HJ; Brenner, J; Catane, R; Chaitchik, S; Farbstein, H; Inbar, MJ; Peretz, T; Rizel, S; Ron, IG; Shani, A; Wigler, N | 1 |
| Bares, R; Bartusek, G; Dittmann, H; Dohmen, BM; Kehlbach, R; Pritzkow, M; Sarbia, M | 1 |
| Gunduz, M; Haisa, M; Naomoto, Y; Shigemitsu, K; Shirakawa, Y; Tanaka, N | 1 |
| Fenner, MH; Possinger, K | 1 |
| Algeri, R; Bian, AR; Bisagni, G; Boni, C; Cocconi, G; Colozza, M; De Angelis, V; Di Sarra, S; Frassoldati, A; Gori, S; Mosconi, AM; Passalacqua, R; Rodinò, C; Rondini, E; Sabbatini, R; Tonato, M | 1 |
| Aschele, C; Bandelloni, R; Barni, S; Cascinu, S; Catalano, V; Debernardis, D; Drudi, G; Gallo, L; Giordani, P; Lonardi, S; Maley, F; Monfardini, S; Turci, D | 1 |
| Anderson, A; Cameron, DA; Crown, J; Evans, TR; Grieve, RJ; Jones, A; Kennedy, IC; Le Vay, JH; Leonard, RC; Mansi, J; Perren, TJ; Toy, E | 1 |
| Aynehchi, S; Choudhury, MS; Drinis, S; Finkelstein, MP; Konno, S; Samadi, AA; Tazaki, H | 1 |
| Maruyama, M; Nagahama, T; Tokairin, Y | 1 |
| Hata, Y; Itoh, T; Maeda, Y; Matsuoka, S; Nakajima, N; Osada, T; Sano, F | 1 |
| Pritchard, KI | 2 |
| Bauernhofer, T; Fridrik, M; Gnant, M; Haider, K; Hausmaninger, H; Jakesz, R; Kubista, E; Kwasny, W; Menzel, C; Mlineritsch, B; Samonigg, H; Seifert, M; Steger, G; Steindorfer, P; Wette, V | 1 |
| Blamey, R; Cuzick, J; de Haes, JC; de Matteis, A; Eiermann, W; Fogelman, I; Geberth, M; Jonat, W; Kaufmann, M; Lisboa, B; Namer, M; Palmer, M; Sauerbrei, W; Schumacher, M; Stewart, A; Szakolczai, I | 1 |
| Athens, JW; Costanzi, JJ; Green, SJ; Lew, D; Martino, S; Osborne, CK; Rivkin, SE; Vaughn, CB | 1 |
| Ives, A; Puckridge, P; Saunders, C; Semmens, J | 1 |
| Shimizu, C; Watanabe, T | 1 |
| Gowda, RV; Stout, R | 1 |
| Balsari, A; Biganzoli, E; Bonadonna, G; Boracchi, P; Casalini, P; Marubini, E; Ménard, S; Moliterni, A; Pilotti, S; Tomasic, G; Valagussa, P | 1 |
| Baldini, E; Bruzzi, P; Collecchi, P; Conte, PF; Evangelista, G; Gardin, G; Giannessi, PG; Lionetto, R; Mosca, F; Prochilo, T; Roncella, M; Rosso, R | 1 |
| Nagykálnai, T | 1 |
| Baron, B; Bleiberg, H; Blijham, GH; Couvreur, ML; De Greve, J; Genicot, B; Jansen, RL; Kok, TC; Nortier, JW; Wagener, T; Wils, J | 1 |
| Liu, J; Rao, XQ; Yu, RC | 1 |
| Bar Sela, G; Gaitini, D; Haim, N; Steiner, M; Tsalic, M | 1 |
| Filipits, M; Jakesz, R; Pirker, R; Pohl, G; Rudas, M; Steger, GG; Stranzl, T; Taucher, S | 1 |
| Becquart, D; Beex, LV; de Haes, JC; Duchateau, L; Engelsman, E; Jassem, J; Klijn, J; Nooij, MA; Wildiers, J | 1 |
| Pater, JL; Pritchard, KI | 1 |
| Buyse, M; Piedbois, P; Zelek, L | 1 |
| Brufsky, A; Faul, C; Flickinger, J; Gerszten, K; Jacob, H; Kunschner, A; Vogel, V | 1 |
| Bertsch, H; Fox, K; Glick, J; Harris, EE; Schultz, D; Solin, LJ | 1 |
| Aihara, H; Kiyozaki, H; Konishi, F; Maruoka, H | 1 |
| Banerjee, D; Bertino, JR; Budak-Alpdogan, T; Capiaux, GM; Maley, F; Mayer-Kuckuk, P; Takebe, N | 1 |
| Accettura, C; Bernard-Marty, C; Cardoso, F; Di Leo, A; Kleiber, K; Larsimont, D; Lobelle, JP; Mano, M; Munoz-Bermeo, R; Paesmans, M; Piccart, MJ; Richard, T | 1 |
| Blomqvist, C; Elomaa, I; Joensuu, H | 1 |
| Ando, Y; Asai, S; Kobayashi, H; Miyachi, H; Takemura, Y | 1 |
| Blondeel, PN; Cocquyt, VF; Daems, KK; Depypere, HT; Hurley, J; Praet, MM; Schelfhout, VR; Serreyn, RF; Silva, OE; Van Belle, SJ | 1 |
| Berry, DA; Bothun, S; Cirrincione, CT; Demakos, E; Falkson, G; Henderson, IC; Holland, JF; Norton, L; Robbins, A; Weiss, RB; Woolf, SH | 1 |
| Berglund, G; Bolund, C; Fornander, T; Nystedt, M; Rutqvist, LE | 1 |
| Kelleher, M; Miles, D | 1 |
| Fiets, WE; Nortier, JW; Struikmans, H; van der Tweel, I; van Helvoirt, RP | 1 |
| Ames, F; Assikis, V; Booser, D; Buzdar, A; Hortobagyi, G; Singletary, E; Smith, T; Theriault, R; Valero, V; Walters, R; Yang, Y | 1 |
| Colleoni, M; Goldhirsch, A | 1 |
| Fridrik, M; Gnant, M; Haider, K; Hausmaninger, H; Jakesz, R; Kolb, R; Kubista, E; Mlineritsch, B; Ploner, F; Samonigg, H; Seifert, M; Steger, G; Steindorfer, P; Stierer, M; Tschurtschenthaler, G | 1 |
| Aidi, S; Amarenco, P; El Amrani, M | 1 |
| Emi, Y; Kakeji, Y; Kimura, Y; Maehara, Y; Sakurai, M; Takahashi, I; Yonemura, Y | 1 |
| Chen, CA; Chen, M | 1 |
| Kuroi, K; Toi, M | 1 |
| Dake, Y; Enomoto, T; Ikeda, H; Kawano, A; Kitano, H; Saitoh, Y; Sakoda, T; Seno, S | 1 |
| Albanell, J; Aranda, J; Campbell, J; Camps, C; Candel, MT; Carrato, A; Casado, A; Diaz-Rubio, E; Gonzalez, R; Lizon, J; Martin, M; Massuti, B; Munarriz, B; Sole-Calvo, A; Villar, A | 1 |
| Ash, D; Dodwell, D; Ulutin, HC | 1 |
| Malayeri, R | 1 |
| Bozcuk, HS; Samur, M | 1 |
| Hutchins, L; Khan, MA; Kohli, M; Mehta, P | 1 |
| Cara, L; Clerc, T; Delpero, JR; Moutardier, V; Tosini, F; Vlieghe, P | 1 |
| Bengtsson, NO; Bergh, J; Blomqvist, C; Hakamies-Blomqvist, L; Luoma, ML; Malmström, P; Mouridsen, H; Ottoson, S; Pluzanska, A; Sjöström, J; Tennvall, L; Valvere, V | 1 |
| Braun, S; Coith, C; Ebel, S; Hemsen, A; Jänicke, F; Kentenich, C; Oberhoff, C; Pantel, K; Riethdorf, S; Thurm, H; Wallwiener, D | 1 |
| Bisagni, G; Camisa, R; Canaletti, R; Carlini, P; Cocconi, G; Cognetti, F; Di Costanzo, F; Gamboni, A; Gasperoni, S; Porrozzi, S; Pucci, F; Rodinò, C; Ruggeri, EM; Zironi, S | 1 |
| Bae, BN; Han, S; Kim, HJ; Kim, HY; Kim, KH; Kim, YD; Park, K | 1 |
| Blamey, R; Cuzick, J; de Haes, JC; Fogelman, I; Jonat, W; Kaufmann, M; Namer, M; Sauerbrei, W; Schumacher, M | 1 |
| Albertsson, P; Lennernäs, B; Lennernäs, H; Norrby, K | 1 |
| Bramwell, V; Crump, M; Levine, M; Pritchard, K; Shepherd, L; Tu, D | 1 |
| Dabrowska, M; Kłaniewski, T; Molenda, W; Swiatoniowski, G | 1 |
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| Baba, Y; Hayashi, S; Ishikawa, T; Kamimura, T; Nomura, K; Oota, H; Yoshida, T | 1 |
| Cardoso, F; Lohrisch, C; Piccart, MJ | 1 |
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| Klos, KS; Shi, D; Smith, TL; Yang, W; Yang, Y; Yao, J; Yu, D; Zhou, X | 1 |
| Jensen, AO; Mejer, J | 1 |
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| BENSON, JW; HOLDEN, WD; KIEHN, CL | 1 |
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| BRADLEY, TR; HERZENBERG, LA; LAW, LW; ROOSA, RA | 1 |
| MEYER, NI; NORA, PF; SCANLON, EF; TARKINGTON, JA | 1 |
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| BIEDLER, JL; GREENBERG, NH; HUTCHISON, DJ; ROBINSON, DL; SCHRECKER, AW; VENDITTI, JM | 1 |
| BIEDLER, JL; HUTCHISON, DJ; SCHRECKER, AW | 1 |
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| NORCROSS, JW; SULLIVAN, RD; WATKINS, E | 1 |
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| CHANDLER, JJ; DONALDSON, SS; FLETCHER, WS | 1 |
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| SULLIVAN, RD; WATKINS, E | 1 |
| HICKEY, RC; JESSE, RH; LETAYF, V; RUFINO, C; VILLARREAL, R | 1 |
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| MRAZEK, RG; SOUTHWICK, HW; STREHL, FW | 1 |
| FREEMAN, RG; KNOX, JM; LANE, M; ROSSMAN, RE | 1 |
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| IGLESIAS, F; KOKAME, GM; KREMENTZ, ET | 1 |
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| DONALDSON, SS; FLETCHER, WS | 1 |
| GASTPAR, H; SCHREINER, L | 1 |
| RUTMAN, RJ | 1 |
| KUKRAL, JC; NORA, PF; PRESTON, FW | 1 |
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| CAVANAGH, D; HERNANDEZ-ROMAN, P; MARTIN, DS | 1 |
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| Allen, KA; Balducci, L; Bercu, BB; Cantor, A; Jacobsen, PB; Kumar, N; Minton, S; Riccardi, D | 1 |
| Fujiwara, K; Ikeda, T; Jinno, H; Kitajima, M; Kubouchi, K | 1 |
| Bellon, JR; Come, SE; Gelman, RS; Harris, JR; Li, X; Recht, A; Shulman, LN; Silver, BJ | 1 |
| Fujita, K; Gotoh, M; Hirata, I; Hongo, H; Katsu, K; Kawabe, S; Ohta, S; Takiuchi, H | 1 |
| Ooi, Y; Rai, Y; Sagara, Y | 1 |
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| Goffin, JR; Rajan, R; Souhami, L | 1 |
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| Aebersold, DM; Altermatt, HJ; Berclaz, G; Djonov, V; Greiner, RH; Gruber, G; Hlushchuk, R | 1 |
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| Bonadonna, G; Gianni, L; Moliterni, A; Valagussa, P; Zambetti, M | 1 |
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| Askmalm, MS; Carstensen, J; Nordenskjöld, B; Olsson, B; Rutqvist, LE; Skoog, L; Stål, O | 1 |
| de Vries, JE; Hartgrink, HH; Kranenbarg, EK; Putter, H; Songun, I; Tesselaar, ME; van de Velde, CJ; van der Bijl, J; van Krieken, JH; Wils, JA | 1 |
| de Vries, EG; Otter, R; Schaapveld, M; van der Graaf, WT; Willemse, PH | 1 |
| Barrett-Lee, P; Cameron, D; Coleman, R; Crown, J; Foster, E; Kennedy, I; Ledermann, J; Leonard, RC; Lind, M; Perren, T; Twelves, C; van Belle, S; Verrill, M; Wilson, C; Yellowlees, A | 1 |
| Blomqvist, C; Elomaa, I; Saarto, T; Taskinen, MR; Vehmanen, L | 1 |
| Anderson, S; Day, R; Fisher, B; Ganz, PA; Kopec, JA; Land, SR; Tang, G; Wolmark, N; Yothers, G | 1 |
| Hyodo, I; Ikeda, N; Iwase, H; Ohtsu, A; Saito, H; Shimada, Y; Shirao, K; Tamura, T; Tsuji, Y; Yamamoto, S; Yamao, T; Yoshida, S | 1 |
| Andrews, SM; Brown, JR; Garrett, WV; Pickering, D | 1 |
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| Aschele, C; Bandelloni, R; Casazza, S; Debernardis, D; Gallo, L; Lonardi, S; Monfardini, S | 1 |
| Abe, R; Aoyama, H; Asaga, T; Awane, H; Danno, M; Ikeda, T; Kimura, M; Koyama, H; Mitsuyama, S; Nishi, T; Ogita, M; Sano, M; Takashima, S; Takatsuka, Y; Toi, M; Tominaga, T; Wada, T; Yoshida, M | 1 |
| Abe, H; Endo, Y; Hanasawa, K; Kushima, R; Naitoh, H; Tani, T | 1 |
| Blomqvist, C; Elomaa, I; Risteli, J; Risteli, L; Saarto, T; Vehmanen, L | 1 |
| Barni, S; Belvedere, O; Beretta, GD; Frontini, L; Grossi, F; Guglielmi, A; Labianca, R; Pella, N; Puglisi, F; Sobrero, A; Zaniboni, A | 1 |
| Anderson, S; Bryant, J; Deutsch, M; Jeong, JH; Mamounas, E; Taghian, A; Wolmark, N | 1 |
| Escher, H; Fischer, J; von Allmen, G; Wasem, Ch | 1 |
| Angelov, G; Beloeil, L; Marvel, J; Michallet, MC; Quéméneur, L; Revillard, JP; Tomkowiak, M | 1 |
| Bielawski, KP; Bosse, U; Schlotter, CM; Vogt, U | 1 |
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| Hobbs, KB; Kroll, DJ; Seewaldt, VL; Shaw, HS | 1 |
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| Croxford, R; Kim, YI; Lucock, M; Moskovitz, DN; Novakovic, P; Smirnakis, F; Sohn, KJ; Yates, Z | 1 |
| Bernhard, J; Castiglione-Gertsch, M; Coates, AS; Collins, J; Crivellari, D; Fey, MF; Forbes, JF; Gelber, RD; Goldhirsch, A; Hürny, C; Murray, E; Perey, L; Price, KN; Rudenstam, CM; Snyder, R; Thürlimann, B; Veronesi, A; Zahrieh, D | 1 |
| Ebuchi, M; Hasegawa, K; Katoh, K; Koide, A; Maruyama, M; Maruyama, S; Ohbe, M; Shinoura, Y; Takashima, K | 1 |
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| Anderson, S; Fisher, B; Jeong, JH; Wolmark, N | 1 |
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| Castleberry, RP; Douglass, EC; Fontanesi, J; London, WB; Pappo, AS; Rodriguez-Galindo, C; Swanson, GP; Wofford, M | 1 |
| Azpeitia, D; Benito, E; Escobedo, A; Falo, C; Lloveras, B; Moreno, A; Prieto, L; Serra, JM; Varela, M | 1 |
| Bonadonna, G; Daidone, MG; Gianni, L; Moliterni, A; Pilotti, S; Valagussa, P; Zambetti, M | 1 |
| Coldman, AJ; Coppin, CM; Durand, R; Gelmon, K; Jackson, SM; Knowling, MA; Le, N; Manji, M; Olivotto, IA; Phillips, N; Ragaz, J; Spinelli, JJ; Weir, L; Wilson, KS | 1 |
| Altundag, K; Atahan, L; Baltali, E; Cengiz, M; Erol, K; Guler, N; Onat, DA; Ozisik, Y; Sayek, I; Tekuzman, G | 1 |
| Adamo, V; Bianco, AR; Costanzo, R; D'Aprile, M; De Laurentiis, M; De Lena, M; De Placido, S; Farris, A; Ferraù, F; Lauria, R; Limite, G; Lorusso, V; Manzione, L; Pagliarulo, C; Palazzo, S; Palmeri, S; Paradiso, A; Petrella, G; Pistillucci, G; Sarobba, MG | 1 |
| Cecchin, E; Toffoli, G | 1 |
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| Dietze, O; Filipits, M; Grill, R; Hausmaninger, H; Jakesz, R; Kubista, E; Lax, S; Pirker, R; Pohl, G; Rudas, M; Samonigg, H; Zielinski, CC | 1 |
| Barbieri, A; Sabatini, L; Tosi, M; Violante, FS | 1 |
| Ohtake, T; Okayama, H; Sagara, H; Takenoshita, S; Watanabe, K; Yasuda, M | 1 |
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| Fu, JH; Huang, ZF; Lin, P; Long, H; Rong, TH; Tang, J; Wang, SY; Wang, X; Yang, MT; Zeng, CG | 1 |
| Bellon, JR; Come, SE; Gelman, RS; Harris, JR; Henderson, IC; Recht, A; Shulman, LN; Silver, BJ | 1 |
| Amabile, G; Capasso, I; D'Aiuto, G; De Maio, E; de Matteis, A; Di Maio, M; Elmo, M; Gravina, A; Labonia, V; Landi, G; Morrica, B; Nuzzo, F; Pacilio, C; Perrone, F; Rinaldo, M; Rossi, E | 1 |
| Andersson, J; Bergh, J; Carlsson, G; Gustavsson, B; Holmberg, L; Inganäs, M; Klaar, S; Larsson, L; Nilsson, J; Ohd, J; Rudenstam, CM | 1 |
| Castiglione-Gertsch, M; Coates, AS; Colleoni, M; Collins, J; Crivellari, D; Erzen, D; Forbes, J; Gelber, RD; Goldhirsch, A; Holmberg, S; Li, S; Lindtner, J; Murray, E; Pagani, O; Price, KN; Rudenstam, CM; Simoncini, E; Thürlimann, B; Veronesi, A | 1 |
| Mazeron, JJ | 1 |
| Guan, YL; Jang, AY; Long, ZQ; Wang, YX; Zhang, X | 1 |
| Awada, A; Canney, P; Kerr, J; Mano, MS | 1 |
| Ishikawa, T; Kamimura, T; Mizuno, K; Ohta, H; Seki, K; Togashi, T; Watanabe, K; Yoshida, T | 2 |
| Carlini, P; Cognetti, F; De Marco, S; Giannarelli, D; Nardi, M; Pinnarò, P; Pollera, CF; Ruggeri, EM; Ruscito, P | 1 |
| Chaturvedi, A; Drew, PJ; Julius, T; Kemp, SE; Kneeshaw, PJ; Turnbull, LW | 1 |
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| Blomqvist, C; Larsson, R; Nygren, P; Villman, K | 1 |
| Bonadonna, G; Demicheli, R; Hrushesky, WJ; Miceli, R; Moliterni, A; Retsky, MW; Valagussa, P; Zambetti, M | 1 |
| Bella, MA; Bisagni, G; Boni, C; Bruzzi, P; Camisa, R; Cocconi, G; Di Blasio, B; Leonardi, F; Rondini, E; Savoldi, L; Vallisneri, C | 1 |
| Ellis, PA; Galani, E; Jones, A; Ring, AE; Shannon, C; Smith, IE | 1 |
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| Matsuda, H; Mikami, Y; Nagao, J; Sakuma, N; Tsukuda, M; Yoshida, T | 1 |
| Brogan, K; Howard, J; Hudis, C; Hurria, A; Jakubowski, A; Norton, L; Panageas, KS; Pearce, C; Zauderer, M | 1 |
| Bartsch, R; Gnant, MF; Hussian, D; Jakesz, R; Locker, GJ; Pluschnig, U; Rudas, M; Steger, GG; Wenzel, C; Zielinski, CC | 1 |
| Klaamas, K; Kurtenkov, O; Miljukhina, L; Rittenhouse-Olson, K; Sergejev, B; Shljapnikova, L; Vahter, L | 1 |
| Horie, T; Tomimatsu, T | 1 |
| Cathomas, R; Murray, N; Pelosi, E; Simmonds, P; Smart, J | 1 |
| Egawa, N; Kamisawa, T; Karasawa, K; Matsuda, T; Okamoto, A; Tsuruta, K; Tu, Y | 1 |
| Bleiker, TO; Hutchinson, PE; Nicolaou, N; Traulsen, J | 1 |
| Gunduz, U; Gurhan, I; Hasirci, N; Muvaffak, A | 1 |
| Bramwell, VH; Levine, MN; Paul, N; Pritchard, KI; Shepherd, LE; Tu, D | 1 |
| Blomqvist, C; Elomaa, I; Saarto, T; Taube, T; Vehmanen, L | 1 |
| Ahlgren, J; Amini, RM; Blomqvist, C; Poikonen, P; Sjöström, J; Villman, K | 1 |
| Chernozemsky, I; Chilingirov, P; Fritze, D; Kaufmann, M; Kleeberg, U; Loibl, S; Marschner, N; Merkle, Kh; Sirakova, L; Souchon, R; Stuart, N; Thomssen, C; Tsekov, C; Vermorken, JB; von Minckwitz, G | 1 |
| Vastag, B | 1 |
| Hiramatsu, K; Mizukami, Y; Momiyama, M; Nagashima, T; Niimi, K; Suzuki, M | 1 |
| Cantor, JP; Curcillo, PG; Lucarelli, EA; Meltzer, AJ; Schwartz, GF | 1 |
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| Brossard, D; Crauste-Manciet, S; Ferrari, S; Jomier, JY; Sessink, PJ | 1 |
| Bramwell, V; Day, AG; Levine, M; Ottaway, JA; Parulekar, WR; Pritchard, KI; Shepherd, LE; Trudeau, ME | 1 |
| Cold, S; Düring, M; Ewertz, M; Knoop, A; Møller, S | 1 |
| Bian, AR; Bisagni, G; Bucciarelli, E; Cavaliere, A; Cherubini, R; Colozza, M; De Angelis, V; Frassoldati, A; Gori, S; Mazzocchi, B; Mihailova, Z; Mosconi, AM; Rodino, C; Sidoni, A; Tonato, M | 1 |
| Aravantinos, G; Bafaloukos, D; Briasoulis, E; Christodoulou, C; Dafni, U; Dimopoulos, AM; Fountzilas, G; Gogas, H; Kalofonos, HP; Kosmidis, P; Makrantonakis, P; Markopoulos, C; Papadimitriou, C; Papakostas, P; Pectasides, D; Polychronis, A; Razis, E; Siafaka, V; Skarlos, D; Timotheadou, E; Tsavdaridis, D | 1 |
| Khanam, A; Mehreen, L | 1 |
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| Boogerd, W; Hamburger, HL; Kreukels, BP; Ridderinkhof, KR; Schagen, SB; van Dam, FS | 1 |
| Bonetti, M; Carbone, A; Castiglione-Gertsch, M; Coates, AS; Collins, J; Crivellari, D; Fey, MF; Gelber, RD; Goldhirsch, A; Golouh, R; Gruber, G; Holmberg, SB; Lindtner, J; Nasi, ML; Price, KN; Rudenstam, CM; Simoncini, E; Thürlimann, B | 1 |
| Sanuki-Fujimoto, N | 1 |
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| Boynton, A; Robien, K; Ulrich, CM | 1 |
| Arcangeli, G; Benassi, M; Giannarelli, D; Pinnarò, P; Rambone, R | 1 |
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| Hamada, T; Ichimura, W; Minagawa, N; Mino, K; Naito, H; Orimo, T; Shibazaki, W; Shinohara, T | 1 |
| Balslev, E; Ejlertsen, B; Gunnarsdóttir, K; Knoop, AS; Knudsen, H; Mouridsen, H; Nielsen, KV; Olsen, KE; Overgaard, J; Rasmussen, BB; Schonau, A | 1 |
| Charbonneau, F; Gelmon, K; Laing, K; Latreille, J; Mackey, J; McLeod, D; Pritchard, K; Provencher, L; Trudeau, M; Verma, S | 1 |
| Albert, US; Conrad, B; Eiermann, W; Gademann, G; Geberth, M; Graf, E; Jonat, W; Kaufmann, M; Schumacher, M; Stahl, K; von Minckwitz, G | 1 |
| Ajarim, DS; Ezzat, AA; Ibrahim, EM; Rahal, MM; Raja, MM | 1 |
| Dodd, M; Dowling, G; Jansen, C; Kramer, J; Miaskowski, C | 1 |
| Alagol, H; Atalay, C; Camlibel, M; Dinc, S; Gulcelik, MA; Kuru, B | 1 |
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| Baron, B; Bliss, JM; Conte, PF; Coombes, RC; Couvreur, ML; Crivellari, D; Dos Santos, JG; Emson, M; Fountzilas, G; Hall, E; Homewood, J; Lise, M; Marchet, A; Nitti, D; Sanchez, E; Sava, C; Tres, A; Van Cutsem, E; Wils, J; Woods, E | 1 |
| Abeloff, M; Allred, C; Green, SJ; Hutchins, LF; Lew, D; Lyss, AP; Martino, S; Osborne, CK; Ravdin, PM; Rivkin, SE | 1 |
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| King, MM; Osswald, MB | 1 |
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| Blohmer, JU; Breitbach, GP; Budner, M; Elling, D; Kohls, A; Krocker, J; Kümmel, S; Lichtenegger, W; Morack, G | 1 |
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| Cheung, PS; Epstein, RJ; Leung, TW | 1 |
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| Chen, JH; Han, GX; Shuai, XM; Wang, GB | 1 |
| Bernhard, H; Harbeck, N; Heinemann, V; Lässig, D; Schmitt, M; Schoenberg, S; Stemmler, HJ; Willems, A | 1 |
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| Horiuchi, C; Ishitoya, J; Katori, H; Matsuda, H; Mikami, Y; Nishimura, G; Taguchi, T; Tsukuda, M; Yoshida, T | 1 |
| Abraham, D; Aharinejad, S; Paulus, P; Schäfer, R; Stanley, ER | 1 |
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| Blohmer, JU; Breitbach, GP; Budner, M; Elling, D; Kohls, A; Krocker, J; Kümmel, S; Morack, G | 1 |
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| Cheng, BB; Gu, W; Han, J; Li, B; Ling, CQ; Zhang, YN | 1 |
| Higuchi, K; Koizumi, W; Nakayama, N; Saigenji, K; Sasaki, T; Tanabe, S | 1 |
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| Wan, X; Xiang, Y; Yang, J; Yang, X | 1 |
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| Casado, FJ; Gloeckner-Hofmann, K; Guillén-Gómez, E; Pastor-Anglada, M; Porstmann, R; Rüschoff, J; Schmidtgen, C; Stoss, O; Ziegler, R | 1 |
| Brody, JR; Canto, MI; Gallmeier, E; Hruban, RH; Hucl, T; Kern, SE; Kulesza, P; Schulick, RD; Yoshimura, K | 1 |
| An, R; Han, X; Wang, S; Xue, Y; Zhu, K | 1 |
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| Binns, MA; Kerr, L; Tannock, I; Vardy, J; Winocur, G | 1 |
| Koizumi, W; Nakayama, N; Saigenji, K; Sasaki, T; Tanabe, S | 1 |
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| Gordon, NH; Lasheen, W; Meinert, J; Silverman, P; Siminoff, LA | 1 |
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| Agrawal, RK; Bathers, S; Brunt, AM; Crawford, SM; Dunn, JA; Earl, HM; Fernando, IN; Foster, L; Grieve, RJ; Harvey, P; Hiller, L; Leonard, RC; Mansi, JL; McAdam, K; O'Reilly, SM; Poole, CJ; Rea, DW; Simmonds, P; Spooner, DA; Stanley, A; Twelves, CJ | 1 |
| Levine, MN; Whelan, T | 1 |
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| Chaturvedi, A; Drew, PJ; Fox, JN; Garimella, V; Long, ED; Qutob, O; Turnbull, LW | 1 |
| Fasolo, A; Gianni, L; Marchiano, A; Mariani, G; Moliterni, A; Petrelli, F; Valagussa, P; Zambetti, M | 1 |
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| Brünner, N; Christensen, IJ; Foekens, JA; Holten-Andersen, MN; Look, MP; Meijer-van Gelder, ME; Mouridsen, HT; Schrohl, AS | 1 |
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| Gamulin, M; Garaj-Vrhovac, V; Kopjar, N; Milas, I | 1 |
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| Jensen, AB; Johansson, A; Mehlsen, M; Paulsen, K; von der Maase, H; Zachariae, R | 2 |
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| Nielsen, HM; Overgaard, J; Overgaard, M | 1 |
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| Antonini, N; Bais, E; Horenblas, S; Kerst, JM; Leijte, JA | 1 |
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| Buchholz, TA; Olivotto, IA; Ragaz, J; Thames, HD; Truong, PT; Woodward, WA | 1 |
| Li, JG; Wan, XR; Xiang, Y; Yang, JJ; Yang, XY | 1 |
| Bischoff, J; Costa, SD | 1 |
| Castiglione-Gertsch, M; Coates, AS; Colleoni, M; Gelber, RD; Gelber, S; Goldhirsch, A; Pagani, O; Price, KN; Simoncini, E | 1 |
| Amaddeo, P; Barbaglio, A; Faldi, F; Fontana, S; Ghilardi, R; Pericotti, S | 1 |
| Ahnström Waltersson, M; Bostner, J; Fornander, T; Nordenskjöld, B; Skoog, L; Stål, O | 1 |
| Johansen, J; Overgaard, J; Overgaard, M | 1 |
| Barreau-Pouhaer, L; Bonhomme-Faivre, L; Mathieu, MC; Rouzier, R; Seiller, M; Travagli, JP | 1 |
| Castiglione-Gertsch, M; Gelber, RD; Gelber, S; Goldhirsch, A; Partridge, A; Winer, E | 1 |
| Amadori, D; Becciolini, A; Casadei Giunchi, D; Gambi, A; Livi, L; Luzi Fedeli, S; Marangolo, M; Nanni, O; Perroni, D; Ravaioli, A; Rossi, AP; Scarpi, E; Silvestrini, R; Volpi, A | 1 |
| Bowen, D; Davis, JH; Desoto, JA; Fryar, EB; Southerland, WM | 1 |
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| Abraham, BK; Brauch, H; Fritz, P; Illig, T; Jaremko, M; Justenhoven, C; Schroth, W; Schwab, M; Simon, W; Vollmert, C | 1 |
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| Alonso, C; Altés, A; Baiget, M; Barnadas, A; Del Rio, E; Paré, L; Ramón y Cajal, T; Sedano, L | 1 |
| Cerno, M; Damiani, D; Fanin, R; Geromin, A; Grimaz, S; Rinaldi, C; Skert, C; Sperotto, A | 1 |
| Chao, TY; Chiang, YH; Lin, CS; Lin, SH; Sheu, LF | 1 |
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| Dengler, R; Fröhlich, F; Kroll, T; Lobodasch, K; Pachmann, K; Pachmann, U; Rengsberger, M; Schubert, R | 1 |
| Aebi, S; Byrne, M; Castiglione-Gertsch, M; Coates, AS; Cole, BF; Colleoni, M; Crivellari, D; Gianni, L; Goldhirsch, A; Holmberg, SB; Pagani, O; Panzini, I; Price, KN; Ravaioli, A; Simoncini, E; Snyder, R | 1 |
| Ae, T; Higuchi, K; Ishido, K; Katada, C; Koizumi, W; Nakatani, K; Saigenji, K; Sasaki, T; Tanabe, S | 1 |
| Borkhardt, A; Debatin, KM; Ehrhardt, H; Fulda, S; Häcker, S; Jeremias, I; Maurer, M; Toloczko, A; Wittmann, S | 1 |
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| Chen, L; Fan, Y; Fu, L; Guo, XJ; Lang, RG; Sun, YL | 1 |
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| Ejlertsen, B; Kamby, C | 1 |
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| Chen, Y; Fu, M; Liang, X; Lin, C; Ma, Y; Qian, H; Wang, H; Xiang, Y; Zhan, Q; Zhang, X | 1 |
| Arriagada, R; Bourgier, C | 1 |
| Debus, J; Milker-Zabel, S; Wannenmacher, M; Zabel-du Bois, A | 1 |
| Eucker, J; Kühnl, A; Possinger, K | 1 |
| Aebi, S; Castiglione-Gertsch, M; Rabaglio, M | 1 |
| Guo, XT; Liu, WC; Xue, Y | 1 |
| Han, JQ; Li, XQ; Liang, RX; Liu, Q; Qu, FS; Sun, YH; Yan, TX | 1 |
| Niu, R; Shi, Y; Wang, D; Wei, X; Yang, Y; Yu, M; Zhang, N | 1 |
| Bafaloukos, D; Briasoulis, E; Dafni, U; Dimitrakakis, K; Dimopoulos, AM; Fountzilas, G; Gogas, H; Kalofonos, HP; Karanikiotis, C; Karina, M; Linardou, H; Makrantonakis, P; Markopoulos, C; Papadimitriou, C; Papakostas, P; Pectasides, D; Pisanidis, N; Polichronis, A; Samantas, E; Skarlos, D; Stathopoulos, GP; Tzorakoeleftherakis, E; Varthalitis, I; Xiros, N | 1 |
| Abu-Saad, HH; Courtens, AM; de Jong, N; Kester, AD; Schouten, HC | 1 |
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| Dubsky, P; Gnant, M; Greil, R; Jakesz, R; Kwasny, W; Poestlberger, S; Reiner, G; Samonigg, H; Schippinger, W; Steger, GG; Taucher, S; Tausch, C; Tschmelitsch, J; Wette, V | 1 |
| Anton-Culver, H; Begg, CB; Bernstein, JL; Bernstein, L; Bertelsen, L; Boice, JD; Capanu, M; Christensen, J; Ejlertsen, B; Haile, RW; Langholz, B; Lynch, CF; Malone, KE; Mellemkjaer, L; Olsen, JH; Shore, RE; Stovall, M; Thomas, DC | 1 |
| Colozza, M; D'Aiuto, G; De Maio, E; de Matteis, A; De Placido, S; Di Rella, F; Gallo, C; Gori, S; Gravina, A; Labonia, V; Landi, G; Lauria, R; Morabito, A; Nuzzo, F; Pacilio, C; Perrone, F; Piccirillo, MC; Rossi, E; Signoriello, G; Thomas, R | 1 |
| Rödel, C; Sauer, R; Weiss, C | 1 |
| Berdel, WE; Diallo-Danebrock, R; Frick, M; Gluz, O; Harbeck, N; Herr, A; Jackisch, C; Kates, R; Kirchner, H; Lindemann, W; Metzner, B; Mohrmann, S; Nitz, UA; Poremba, C; Schütt, G; Ting, E; Werner, F | 1 |
| Andersson, M; Balil, A; Bendahmane, B; Buyse, M; Castiglione-Gertsch, M; Crown, J; Di Leo, A; Dolci, S; Francis, P; Gelber, RD; Goldhirsch, A; Gutiérrez, J; Jakesz, R; Jamin, S; Lang, I; Nordenskjöld, B; Piccart-Gebhart, M; van Hazel, G; Vorobiof, D | 1 |
| Alamani, M; Arapantoni-Dadioti, P; Aravantinos, G; Briasoulis, E; Dafni, U; Fountzilas, G; Gogas, H; Kalofonos, HP; Kastritis, E; Kostopoulos, I; Kyriakou, V; Kyroudi, A; Malamou-Mitsi, V; Papaspyrou, I; Pectasides, D; Skopa, C; Tzaida, O | 1 |
| Bianchi, S; Biti, GP; Borghesi, S; Cataliotti, L; Leonulli, BG; Livi, L; Meattini, I; Paiar, F; Paoletti, L; Petrucci, A; Rampini, A; Saieva, C; Scoccianti, S | 1 |
| Liu, Y; Zhang, J | 1 |
| Bonadonna, G; Valagussa, P; Veronesi, U | 1 |
| Albain, KS; Dakhil, SR; Ganz, PA; Giguere, JK; Goodwin, JW; Hussey, MA; Hutchins, LF; Martino, S; Moinpour, CM; Unger, JM | 1 |
| Bachrich, T; Fink-Retter, A; Gschwantler-Kaulich, D; Hudelist, G; Kubista, E; Ledesma, M; Ruecklinger, E; Singer, CF | 1 |
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| Brown, RW; Castiglione-Gertsch, M; Coates, AS; Colleoni, M; Gelber, RD; Goldhirsch, A; Golouh, R; Gusterson, BA; Kovács, A; Maffini, F; Maiorano, E; Mastropasqua, MG; Ohlschlegel, C; Perin, T; Pillay, K; Price, KN; Regan, MM; Viale, G | 1 |
| Maggioni, F; Palmieri, A; Tropea, M; Zanchin, G | 1 |
| Castiglione-Gertsch, M; Coates, A; Gianni, L; Goldhirsch, A; Gusterson, BA; Maffini, F; Mastropasqua, MG; Monti, F; Panzini, I; Price, KN; Ravaioli, A; Regan, MM; Spataro, V; Viale, G | 1 |
| Akashi-Tanaka, S; Ando, M; Fujiwara, Y; Hojo, T; Katsumata, N; Kinoshita, T; Kohno, T; Seki, K; Shibata, T; Shien, T; Shimizu, C | 1 |
| Berry, D; Bhalla, K; Cirrincione, C; Duggan, DB; Henderson, IC; Hudis, C; Kimmick, GG; Lemke, S; Norton, L; Robert, N; Winer, E | 1 |
| Caputo, A; Schmoor, C; Schumacher, M | 1 |
| Abel, U; Bauer, C; Borho, K; Gerhard, I; Kuehn, JJ; Loewe-Mesch, A; Schneeweiss, A; Sohn, C; Strowitzki, T; v Hagens, C | 1 |
| Agarwal, JP; Gupta, T; Jain, S; Menon, H; Mistry, RC; Parikh, PM; Pramesh, CS; Shrivastava, SK | 1 |
| Dietze, O; Filipits, M; Gnant, MF; Greil, R; Grill, R; Huynh, A; Jakesz, R; Kwasny, W; Lax, S; Lehnert, M; Rudas, M; Schippinger, W; Singer, C; Stierer, M; Stiglbauer, W | 1 |
| Royston, P; Sauerbrei, W | 1 |
| Braye, S; Brown, RW; Castiglione-Gertsch, M; Coates, AS; Gelber, RD; Goldhirsch, A; Golouh, R; Grigolato, P; Gusterson, BA; Kovács, A; Maiorano, E; Mastropasqua, MG; Ohlschlegel, C; Perin, T; Pillay, K; Price, KN; Regan, MM; Rusca, T; Viale, G | 1 |
| Bowen, JM; Gibson, RJ; Keefe, DM; Logan, RM; Sonis, ST; Stringer, AM | 2 |
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| Bartsch, R; Denison, U; Dubsky, P; Fridrik, M; Gnant, M; Greil, R; Hausmaninger, H; Jakesz, R; Kwasny, W; Mlineritsch, B; Pötter, R; Samonigg, H; Schippinger, W; Seifert, M; Sevelda, P; Steger, G; Stierer, M; Stöger, H; Taucher, S | 1 |
| Ceccarelli, C; Derenzini, M; Donati, G; Mazzini, G; Montanaro, L; Santini, D; Taffurelli, M; Treré, D; Vici, M | 1 |
| Castiglione-Gertsch, M; Coates, AS; Cole, BF; Collins, J; Crivellari, D; Fey, MF; Gelber, RD; Goldhirsch, A; Golouh, R; Gruber, G; Gusterson, BA; Holmberg, SB; Lindtner, J; Price, KN; Simoncini, E; Thürlimann, B; Viale, G | 1 |
| Baker, LH; Crawford, ED; Faulkner, J; Higano, CS; Hussain, M; Meyers, FJ; Rivkin, SE; Russell, KJ; Sakr, WA; Tangen, CM | 1 |
| Foley, JJ; Raffa, RB; Walker, EA | 1 |
| Ejlertsen, B; Jensen, MB; Mouridsen, HT | 1 |
| Andersen, J; Cold, S; Ejlertsen, B; Ewertz, M; Jakobsen, E; Jensen, MB; Kamby, C; Mouridsen, HT; Sørensen, PG | 1 |
| Ejlertsen, B; Jørgensen, JT; Knoop, A; Knudsen, H; Mouridsen, HT; Møller, S; Nielsen, KV | 1 |
| Andersen, J; Bergh, J; Bjerregaard, B; Cold, S; Edlund, P; Ejlertsen, B; Ewertz, M; Jensen, MB; Kamby, C; Kristensen, B; Lindman, H; Mouridsen, HT; Nordenskjöld, B | 1 |
| Chen, WK; Chen, YF; Guo, ZM; Su, YR; Wei, MW; Wu, GH; Zeng, ZY | 1 |
| Hayashi, S; Karaki, H; Sugano, I; Sugimoto, K; Suzuki, H; Takayanagi, H; Yamamori, H; Yamamoto, K | 1 |
| Boogerd, W; Kreukels, BP; Ridderinkhof, KR; Schagen, SB; van Dam, FS | 1 |
| Boku, N; Fukuda, H; Hamaguchi, T; Honma, H; Hyodo, I; Imamura, T; Koizumi, W; Mukai, T; Ohtsu, A; Seki, S; Shirao, K; Yamamichi, N; Yamamoto, S; Yoshida, S | 1 |
| Kudriavtsev, DV; Kudriavtseva, GT; Mardynskiĭ, IuS | 1 |
| Barbarot, V; Courant-Menanteau, M; Lewden-Bernadac, B; Perrocheau, G; Thomare, P | 1 |
| Bergmann, OJ; Brünner, N; Jensen, SB; Mouridsen, HT; Nauntofte, B; Reibel, J | 1 |
| Andersson, M; Azambuja, E; Balil, A; Crown, JP; Dolci, S; Francis, P; Gelber, RD; Gnant, M; Gutierrez, J; Láng, I; Nordenskjöld, B; Pestalozzi, BC; Piccart-Gebhart, M; Quinaux, E; Viale, G | 1 |
| Aravantinos, G; Bamias, A; Fountzilas, G; Papadimitriou, CA; Papakostas, P; Timotheadou, E | 1 |
| Coccaro, M; Gallucci, G | 1 |
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| Andersen, PK; Cortese, G; Nielsen, D; Nielsen, G; Ryberg, M; Skovsgaard, T | 1 |
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| Ehrlichman, RS; Gandal, MJ; Rudnick, ND; Siegel, SJ | 1 |
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| Castiglione-Gertsch, M; Coates, AS; Collins, J; Crivellari, D; Fey, MF; Forbes, JF; Gelber, RD; Gelber, S; Goldhirsch, A; Holmberg, SB; Lindtner, J; Murray, E; Pagani, O; Price, KN; Simoncini, E; Thürlimann, B | 1 |
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| Beauduin, M; Closon-Dejardin, MT; Cornez, N; de Azambuja, E; di Leo, A; Dolci, S; Finet, C; Focan, C; Gobert, P; Kerger, J; Nogaret, JM; Paesmans, M; Piccart-Gebhart, MJ; Ries, F; Tagnon, A; Vindevoghel, A | 1 |
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| Beraki, E; Kåresen, R; Naume, B; Park, D; Sauer, T; Synnestvedt, M | 1 |
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| Ariyama, H; Baba, E; Esaki, T; Fujimoto, C; Hiranuma, S; Murakawa, M; Syoji, T; Tsukasa, K | 1 |
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| Aoshima, K; Kadowaki, T; Oda, Y; Tanaka, M; Tanaka, S; Uehara, T; Yokoi, A | 1 |
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| Kaji, H; Maiguma, T; Makino, K; Teshima, D | 1 |
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| Jeong, JH; Luong, TM; Wahed, AS | 1 |
| Becker, HP; Berry, DA; Burstein, HJ; Cirrincione, CT; Cohen, HJ; Dressler, LG; Gralow, JR; Grenier, D; Hart, RD; Hudis, CA; Kartcheske, PA; Kornblith, AB; Magrinat, G; Mahmood, AA; Mauer, AM; Muss, HB; Norton, L; Parker, BA; Partridge, AH; Perez, EA; Theodoulou, M; Wheeler, JD; Winer, EP; Wolff, AC | 1 |
| Kim, YI | 1 |
| Cao, Y; Feng, F; Wan, X; Xiang, Y; Yang, X | 1 |
| Balslev, E; Bartels, A; Brünner, N; Ejlertsen, B; Hertel, PB; Jensen, MB; Mouridsen, H; Rasmussen, BB; Willemoe, GL | 1 |
| Brighenti, E; Ceccarelli, C; Derenzini, M; Donati, G; Montanaro, L; Santini, D; Taffurelli, M; Treré, D | 1 |
| Abe, R; Kimijima, I; Kimura, M; Koyama, H; Miura, S; Nomura, Y; Ohashi, Y; Takashima, S; Takatsuka, Y; Tashiro, H; Toi, M; Tominaga, T | 1 |
| Brown, RW; Castiglione-Gertsch, M; Coates, AS; Colleoni, M; Crivellari, D; Gelber, RD; Giobbie-Hurder, A; Goldhirsch, A; Golouh, R; Gusterson, BA; Karlsson, P; Maiorano, E; Mallon, E; Mastropasqua, MG; Öhlschlegel, C; Price, KN; Regan, MM; Sonzogni, A; Viale, G | 1 |
| Bezemer, R; Ince, C; Lindeboom, JA; Milstein, DM | 1 |
| Asaga, T; Higaki, K; Inaji, H; Ito, T; Koh, J; Kohno, N; Komichi, H; Koyama, H; Kyono, S; Mitsuyama, S; Nishikawa, H; Ogita, M; Okamura, K; Osaki, A; Park, Y; Saito, T; Suzuki, T; Tanaka, F; Yamazaki, K | 1 |
| Schmitt, M; Sweep, FC | 1 |
| Abeloff, MD; Albain, KS; Ambrosone, CB; Barlow, WE; Blanco, JG; Choi, JY; Davis, W; Hayes, DF; Hong, CC; Hutchins, LF; Livingston, RB; Lyss, AP; Martino, S; Osborne, CK; Rae, JM; Ravdin, PM; Yeh, IT | 1 |
| Mortimer, J; Pal, SK | 1 |
| Ahmed, SI; Aleskandarany, MA; Chan, S; Ellis, IO; Elsheikh, SE; Green, AR; Macmillan, RD; Mohammed, RA; Paish, EC; Powe, DG; Rakha, EA | 1 |
| Chen, CH; Chiang, PH; Kang, CH | 1 |
| Hamaguchi, T; Hirashima, Y; Kato, K; Nakajima, TE; Okita, NT; Shimada, Y; Shirao, K; Takahari, D; Takashima, A; Yamada, Y | 1 |
| Nesković-Konstantinović, Z; Nikolić-Vukosavljević, D; Todorović-Raković, N | 2 |
| Botchkina, GI; Bruheim, S; Fodstad, O; Formentini, A; Gavin, E; Ju, J; Kornmann, M; Kudo, K; Song, B; Wan, Y; Wang, Y; Xi, Y | 1 |
| Bernard, R; Braun, M; Harbeck, N; Ihbe-Heffinger, A; Jacobs, VR; Kuhn, W; Nitz, U; Sattler, D; Wagenpfeil, S | 1 |
| Brünner, N; Foekens, JA; Look, MP; Meijer-van Gelder, ME; Schrohl, AS | 1 |
| Barlett, N; Chen, CH; Grenier, K; Mujic, V; Sussman, H; Toepker, S; Waller, EK | 1 |
| Albain, KS; Ambrosone, CB; Barlow, WE; Choi, JY; Davis, W; Hayes, DF; Hutchins, LR; Livingston, RB; Lyss, AP; Martino, S; Osborne, CK; Rae, JM; Ravdin, PM; Reynolds, W; Tang, L; Yeh, IT | 1 |
| Enomoto, T; Enomoto, Y; Kitano, H; Morizane, R; Nakahara, K; Nosaka, A; Sakoda, T | 1 |
| Bowen, GM; Florell, SF; Hadley, JC; Hadley, ML; Tristani-Firouzi, P | 1 |
| Jager, A; Sleijfer, S; Verweij, J | 1 |
| Teng, KY; Xu, RH | 1 |
| Glaholm, J; Gupta, N; Hackshaw, A; Hutchison, I; Kadalayil, L; Macdougall, H; Monson, K; Tobias, JS | 1 |
| Ataseven, B; Conrad, B; Eiermann, W; Graf, E; Hilfrich, J; Kaufmann, M; Loibl, S; Massinger-Biebl, H; Schumacher, M; Vescia, S; von Minckwitz, G | 1 |
| Pan, IW; Shih, YC; Tsai, YW | 1 |
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| Azad, A; Chionh, F; Jayarajan, J | 1 |
| Avril, N; Avril-Sassen, S; Dose-Schwarz, J; Jänicke, F; Lebeau, A; Mahner, S; Schwaiger, M; Tiling, R; Untch, M; Weber, C | 1 |
| Bianchi, S; Biti, GP; Borghesi, S; Cataliotti, L; De Luca Cardillo, C; Greto, D; Livi, L; Mangoni, M; Paiar, F; Saieva, C; Scotti, V | 1 |
| Inaji, H; Koyama, H; Ohashi, Y; Sano, M; Suzuki, T; Watanabe, T | 1 |
| Budryk, M; Byrski, T; Dent, R; Gronwald, J; Grzybowska, E; Huzarski, T; Lubinski, J; Mierzwa, T; Narod, S; Siolek, M; Stawicka, M; Szwiec, M; Wisniowski, R | 1 |
| Hashimoto, Y; Inamura, Y; Ito, N; Koide, T; Kojima, T; Nagata, H; Suzumura, K | 1 |
| Cao, WF; Cao, XC; Hao, XS; Ning, LS; Niu, Y; Song, YQ; Zhang, B; Zhao, HM | 1 |
| Horiuchi, C; Ikeda, Y; Ishitoya, J; Kawakami, M; Kawano, T; Komatsu, M; Matsuda, H; Niho, T; Nishimura, G; Sakuma, Y; Shiono, O; Taguchi, T; Takahashi, M; Tsukuda, M; Watanabe, M | 1 |
| Balslev, E; Brünner, N; Ejlertsen, B; Hertel, PB; Jensen, MB; Knoop, AS; Mouridsen, HT; Nielsen, KV; Rasmussen, BB; Willemoe, GL | 1 |
| Borstnar, S; Cufer, T; Mozina, B; Sadikov, A | 1 |
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| Baronio, R; Barton, C; Baselga, J; Bozhok, A; Byakhow, M; Ciruelos, E; Climent, MA; Eiermann, W; Feyereislova, A; Gianni, L; Lichinitser, M; Lluch, A; Manikhas, A; Mansutti, M; Ojeda, B; Semiglazov, V; Tjulandin, S; Valagussa, P; Vazquez, F; Zambetti, M | 1 |
| Accorsi, P; Candeloro, G; Necozione, S; Rea, S; Recchia, CO; Recchia, F; Tombolini, V | 1 |
| Hanai, K; Hongoh, S; Inatsuchi, H; Kawakami, M; Nomoto, T; Terachi, T | 1 |
| Andersen, J; Andersson, M; Ejlertsen, B; Jensen, MB; Kamby, C; Knoop, AS; Mouridsen, HT | 1 |
| Conti, F; Di Lauro, L; Foggi, P; Lopez, M; Vici, P; Viola, G | 1 |
| Chai, CY; Jang, MY; Sheen, MC; Sheu, HM; Wang, YW; Wu, CF | 1 |
| Abeloff, MD; Albain, KS; Ambrosone, CB; Barlow, WE; Choi, JY; Davis, W; Hayes, DF; Hortobagyi, GN; Hutchins, LF; Livingston, RB; Lyss, AP; Martino, S; Osborne, CK; Rae, JM; Ravdin, PM; Yao, S; Yeh, IT; Zhao, H | 1 |
| Chishima, T; Hasegawa, S; Ichikawa, Y; Ishikawa, T; Shimizu, D | 1 |
| Hata, K; Hirai, I; Maebeya, S; Miki, Y; Oota, F; Tanaka, T; Tanino, H | 1 |
| Good, LM; High, WA; Miller, MD | 1 |
| Coates, AS; Cole, BF; Colleoni, M; Crivellari, D; Gelber, RD; Goldhirsch, A; Gusterson, BA; Maiorano, E; Mastropasqua, MG; Price, KN; Regan, MM; Viale, G | 1 |
| de Launoit, Y; Dejonghe, MJ; Dessein, AF; Dessein, R; Dumont, P; Figeac, M; Furuichi, Y; Gespach, C; Grard, G; Hebbar, M; Huet, G; Jonckheere, N; Lecellier, CH; Lesuffleur, T; Leteurtre, E; Monté, D; Porchet, N; Prévost, G; Pruvot, FR; Stechly, L; Truant, S | 1 |
| Bonetti, M; Ejlertsen, B; Gelber, RD; Gunnarsdóttir, KA; Jensen, MB; Knoop, A; Mouridsen, H; Zahrieh, D | 1 |
| Agostara, B; Amadori, D; Boccardo, F; Catalano, G; Faedi, M; Farris, A; Gambi, A; Guglielmini, P; Rubagotti, A; Sismondi, P | 1 |
| Isaacson, D; Kupferschmid, M; Roe-Dale, R | 1 |
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| Chung, HC; Hong, S; Jeung, HC; Jung, M; Kim, HS; Moon, YW; Oh, KJ; Rha, SY; Roh, JK; Shin, HJ; Yang, WI | 1 |
| Castranova, V; Guo, NL; Qian, Y; Rathnagiriswaran, S; Wan, YW | 1 |
| Kirby, JS; Miller, CJ | 1 |
| Greenlaw, N; McArdle, CS; McMillan, DC; Morrison, DS | 1 |
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| Rodríguez-Lescure, A | 1 |
| Gong, R; Meng, X; Xiong, M; Zhong, X | 1 |
| Castiglione-Gertsch, M; Chua, BH; Cole, BF; Colleoni, M; Goldhirsch, A; Gruber, G; Karlsson, P; Murray, E; Price, KN; Roncadin, M | 1 |
| Aygun, N; Bajaj, G; Fakhry, C; Gillison, M; Westra, W | 1 |
| Arcangeli, G; Giannarelli, D; Giordano, C; Pinnarò, P; Rambone, R; Strigari, L | 1 |
| Faradmal, J; Gohari, MR; Hajizadeh, E; Kazemnejad, A; Khodabakhshi, R | 1 |
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| Alavi, N; Bahrami, A; Djavid, GE; Heidari, K; Mehrdad, N; Najafi, M; Najafi, S; Olfatbakhsh, A; Rajaii, E | 1 |
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| Giaccone, G; Rajan, A | 1 |
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| Amadori, D; Amaducci, L; Baldini, E; Biglia, N; Boccardo, F; Bonginelli, P; Brandi, M; De Lena, M; Faedi, M; Gianni, L; Maltoni, R; Paradiso, A; Ponzone, R; Rocca, A; Scarpi, E; Schittulli, F; Serra, P; Silvestrini, R; Tienghi, A; Valerio, MR | 1 |
| Cui, L; Huang, XE; Jiang, Y; Tang, JH; Xiang, J; Yan, PW | 1 |
| Atieh-Graham, D; D'Andrea, G; Drullinsky, P; Fornier, MN; Gilewski, T; Hudis, C; Lake, D; Mills, N; Norton, L; Patel, H; Patil, S; Seidman, AD; Sklarin, N; Sugarman, SM; Traina, T; Troso-Sandoval, T; Wasserheit-Lieblich, C; Yuan, J | 1 |
| Kreienberg, R; Kurzeder, C; Novopashenny, I; Possinger, K; Regierer, AC; Wischnewsky, MB; Wöckel, A; Wolters, R | 1 |
| Brünner, N; Nielsen, KV | 1 |
| Barni, S; Borgonovo, K; Cabiddu, M; Ghilardi, M; Petrelli, F | 1 |
| Banerjee, D; Bertino, JR; Blasberg, RG; Cai, S; de Stanchina, E; Kochetkov, T; Moroz, MA; Nair, J; Schwartz, GK; Serganova, I; Shamis, M; Wu, J | 1 |
| Arriagada, R; Bourgier, C; Dunant, A; Heymann, S; Marsiglia, H; Mathieu, MC; Pessoa, EL; Spielmann, M; Uzan, C | 1 |
| Dizon, DS; Sakr, BJ | 1 |
| Aebi, S; Braun, D; Castiglione-Gertsch, M; Coates, AS; Crivellari, D; Gelber, RD; Goldhirsch, A; Gusterson, BA; Karlsson, P; Lindtner, J; Price, KN; Rabaglio, M; Regan, MM; Simoncini, E; Snyder, R; Sun, Z; Viale, G | 1 |
| Archer, L; Bennett, S; Casey, R; Cohen, HJ; Hudis, C; Kimmick, G; Kornblith, AB; Lan, L; Muss, HB; Partridge, A; Winer, E | 1 |
| Braun, D; Castiglione-Gertsch, M; Coates, AS; Colleoni, M; Collins, J; Crivellari, D; Gelber, RD; Goldhirsch, A; Gusterson, BA; Karlsson, P; Murray, E; Price, KN; Rabaglio, M; Regan, MM; Sun, Z; Viale, G; Zaman, K | 1 |
| Bando, H; Iwata, H; Kashiwaba, M; Mizuno, T; Murakami, S; Nakayama, T; Ohashi, Y; Sawaki, M; Taira, N; Tokudome, N; Uemura, Y; Yamamoto, Y | 1 |
| Beckmann, MW; Conrad, U; Fasching, PA; Fett, W; Harbeck, N; Hasmüller, S; Konecny, GE; Kurzeder, C; Lebeau, A; Lenhard, M; Liedtke, B; Loibl, S; Lück, HJ; Müller, V; Nekljudova, V; Salat, C; Schmidt, M; Stickeler, E; Untch, M; Urbaczyk, H; von Minckwitz, G | 1 |
| Conrad, U; Fasching, PA; Fett, W; Harbeck, N; Hasmüller, S; Konecny, GE; Kurzeder, C; Lebeau, A; Lenhard, M; Liedtke, B; Loibl, S; Lück, HJ; Müller, V; Nekljudova, V; Salat, C; Schmidt, M; Schuster, T; Stickeler, E; Untch, M; Urbaczyk, H; von Koch, F; von Minckwitz, G | 1 |
| Decramer, M; Erven, K; Fieuws, S; Lievens, Y; Nackaerts, K; Weltens, C | 1 |
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| Feng, FZ; Geng, S; Wan, XR; Xiang, Y; Zhou, Y | 1 |
| Bahtiyar, M; Chambers, JT; Chambers, SK; Kohorn, EI; McCaffrey, R; Schwartz, PE | 1 |
| Baak, JP; Gilje, B; Janssen, EA; Nordgård, O; Smaaland, R; Søiland, H; Tjensvoll, K | 1 |
| Ito, N; Koiwai, K; Kubo, N; Nakayama, A; Ogiwara, H; Takeuchi, N; Tsujimoto, K | 1 |
| Arai, Y; Boku, N; Denda, T; Fujii, H; Hamaguchi, T; Hyodo, I; Iwase, H; Koizumi, W; Ohtsu, A; Saito, H; Shirao, K; Takiuchi, H; Yoshida, M | 1 |
| Andrulis, IL; Bramwell, VH; Chia, S; Huntsman, D; Levine, MN; O'Malley, FP; Pritchard, KI; Shepherd, LE; Tu, D | 1 |
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| Jiang, X; Lin, G; Liu, D; Peng, J; Peng, R; Qin, T; Shi, Y; Teng, X; Wang, S; Wang, X; Yuan, Z | 1 |
| Clark-Vetri, R; Foley, JJ; Raffa, RB; Walker, EA | 1 |
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| Burstein, HJ; Curigliano, G; Goldhirsch, A; Munzone, E; Winer, EP | 1 |
| Barrett-Lee, P; Bliss, J; Bloomfield, D; Cameron, D; Campbell, HE; Dunn, J; Earl, H; Ellis, P; Epstein, D; Gray, AM; Griffin, S; Harris, AL; Hiller, L; Hopwood, P; Johnson, L; Manca, A; Poole, C; Sculpher, MJ; Yarnold, J | 1 |
| Boogerd, W; Breteler, MM; Koppelmans, V; Poels, MM; Schagen, SB; Seynaeve, C; van der Lugt, A | 1 |
| Bari, M; Ciruelos, E; De Benedictis, E; Dittrich, C; Gaion, F; Gomez, P; Lluch, A; Luca, G; Mansutti, M; Morandi, P; Pavesi, L; Semiglazov, V; Valagussa, P; Zamagni, C; Zambetti, M | 1 |
| Bighin, C; Boni, L; Cresti, N; Del Mastro, L; Gamucci, T; Garrone, O; Giordano, M; Giraudi, S; Gori, S; Levaggi, A; Magnolfi, E; Michelotti, A; Olmeo, N; Pronzato, P; Scotto, T; Vecchio, C; Venturini, M | 1 |
| Binns, MA; Tannock, I; Winocur, G | 1 |
| Gordon, AM; Hurwitz, S; LeBoff, MS; Shapiro, CL | 1 |
| Brockstein, BE | 1 |
| Chang, SY; Chu, PY; Lirng, JF; Tai, SK; Tsai, TL; Wang, LW; Wang, YF; Yang, MH | 1 |
| Ait-Tihyaty, M; Jean-Claude, BJ; Mihalcioiu, C; Rachid, Z | 1 |
| Bedognetti, D; Boccardo, F; Bruzzi, P; Del Mastro, L; Gardin, G; Monzeglio, C; Pastorino, S; Pronzato, P; Queirolo, P; Sertoli, MR; Siffredi, G; Taveggia, P; Venturini, M; Wang, E; Zanardi, E | 1 |
| Ackland, SP; Byrne, MJ; Coates, AS; Fitzharris, B; Fong, A; Forbes, JF; Francis, PA; Gainford, MC; Gebski, V; Grimison, PS; Harvey, VJ; Nowak, AK; Paksec, L; Simes, RJ; Sourjina, T; Stockler, MR; Van Hazel, G; Wilcken, NR; Zannino, D | 1 |
| Aravantinos, G; Batistatou, A; Bournakis, E; Christodoulou, C; Economopoulos, T; Fountzilas, G; Gogas, H; Kalogeras, KT; Kronenwett, R; Linardou, H; Makatsoris, T; Pavlidis, N; Pectasides, D; Psyrri, A; Timotheadou, E; Wirtz, RM | 1 |
| Balslev, E; Bartels, A; Brünner, N; Ejlertsen, B; Hertel, PB; Jensen, MB; Jiang, S; Nielsen, TO; O'Malley, FP; Pritchard, KI; Shepherd, LE; Tu, D | 1 |
| Kapp, KS; Partl, R; Richtig, E | 1 |
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| Aittomaki, K; Al-Adhami, M; Alaparthi, L; Bartek, J; Bartkova, J; Blomqvist, C; Heikkila, P; Heikkinen, T; Kutok, JL; Meyer, JL; Nevanlinna, H; Pierceall, WE; Sprott, KM; Villegas-Bergazzi, V; Weaver, DT | 1 |
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| Blair, CK; Gulbahce, HE; Knapp, D; Surowiecka, M; Sweeney, C; Varghese, L | 1 |
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| Chen, WW; Cheng, AL; Hsu, CH; Huang, TC; Lin, CC; Yeh, KH | 1 |
| Cho, RC; Cole, PD; Croxford, R; Ishiguro, L; Kamen, BA; Kim, SE; Kim, YI; Ly, A; Sohn, KJ | 1 |
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| Huang, J; Tannock, IF; Winocur, G; Wojtowicz, JM | 1 |
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| Chen, ML; Jeng, C; Lin, YC; Liu, LN; Miaskowski, C; Wang, JS; Wen, FH | 1 |
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| Abdel-Fatah, TM; Ball, GR; Chan, SY; Ellis, IO; Johnson, C; McArdle, SE; Moseley, PM; Pockley, AG; Rees, RC | 1 |
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| Li, S; Liang, X; Liu, J; Wei, L | 1 |
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| Barni, S; Botti, G; Colantuoni, G; D'Aiuto, M; Daniele, B; Daniele, G; De Laurentiis, M; De Maio, E; de Matteis, A; De Placido, S; Di Maio, M; Di Rella, F; Forestieri, V; Gallo, C; Gori, S; Gravina, A; Iodice, G; Labonia, V; Landi, G; Lauria, R; Montanino, A; Morabito, A; Nuzzo, F; Pacilio, C; Perrone, F; Piccirillo, MC; Riccardi, F; Rossi, E; Signoriello, S; Tinessa, V | 1 |
| Tannock, IF; Winocur, G; Wojtowicz, JM | 1 |
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| Ambrogi, F; Ardoino, I; Biganzoli, E; Boracchi, P; Coradini, D; Daidone, MG; Demicheli, R; Moliterni, A | 1 |
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| Bartlett, JM; Caldas, C; Cameron, DA; Cardoso, F; Desmedt, C; Di Leo, A; Dunn, JA; Earl, HM; Ejlertsen, B; Jensen, MB; Larsimont, DP; McConkey, CC; Munro, AF; O'Malley, FP; Poole, CJ; Pritchard, KI; Rea, DW; Shepherd, LE; Twelves, CJ | 1 |
| Bateman, E; Keefe, D; Mayo, B; Stringer, A; Thorpe, D; Vanhoecke, B; Vanlancker, E | 1 |
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| Chen, K; Duan, WM; Gong, FR; Gui, Q; Li, DM; Li, W; Lian, L; Liu, L; Shen, M; Tao, M; Wang, WJ; Wu, MY; Xu, MD; Zhu, J | 1 |
| Cho, E; Ellis, GK; Gadi, VK; Gooley, TA; Linden, HM; Livingston, RB; Rubinstein, LM; Schwemm, AK; Specht, JM; Stevenson, PA | 1 |
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| Chernobrovkin, A; Marin-Vicente, C; Visa, N; Zubarev, RA | 1 |
| Alfer, J; Burchardi, N; Conrad, B; Decker, T; Denkert, C; Eidtmann, H; Eiermann, W; Hackmann, J; Huober, J; Jackisch, C; Loibl, S; Marmé, F; Möbus, V; Nekljudova, V; Potenberg, J; Reimer, T; Simon, E; Stickeler, E; Thomssen, C; von Minckwitz, G | 1 |
| Alexopoulou, Z; Bafaloukos, D; Christodoulou, C; Fountzilas, G; Gogas, H; Kalogeras, KT; Koutras, AK; Kronenwett, R; Linardou, H; Patsea, H; Pavlakis, K; Pectasides, D; Petraki, K; Samantas, E; Scopa, CD; Wirtz, RM; Zagouri, F | 1 |
| Bago-Horvath, Z; Bartsch, R; Bergen, E; Dubsky, P; Exner, R; Gnant, M; Jakesz, R; Mittlböck, M; Ott, J; Panhofer, P; Promberger, R; Rudas, M; Seemann, R; Singer, C; Steger, G | 1 |
| Alpert, A; Cooper, LJ; Olivares, S; Rushworth, D; Santana-Carrero, R; Spencer, D | 1 |
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| Biganzoli, L; Di Leo, A; Hart, CD; Sanna, G; Siclari, O | 1 |
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| Adili, A; Esfehani, A; Jafarpour-Sadegh, F; Mesgari, M; Montazeri, V; Pirouzpanah, S; Rashidi, MR | 1 |
| Broggini, M; Cavalli, IJ; Chilà, R; Damia, G; de Lima, RS; de Oliveira, SF; Ganzinelli, M; Generali, D; Maciel, ME; Ribeiro, EM; Serino, L; Urban, Cde A | 1 |
| Cirrincione, CT; Cohen, HJ; Gralow, J; Hurria, A; Jatoi, A; Lichtman, SM; Magrinat, G; Morganstern, DE; Muss, HB; Theodoulou, M; Wolff, AC | 1 |
| Kato, A; Kuboki, S; Mitsuhashi, N; Miyazaki, M; Ohtsuka, M; Shimizu, H; Shimizu, Y; Yoshitomi, H | 1 |
| Feng, YI; Gao, X; Ji, J; Ji, KE; Jia, Y; Jiang, WG; Satherley, LK; Shao, S; Sun, PH; Ye, L | 1 |
| Calvani, N; Cinieri, S; Fedele, P; Goldhirsch, A; Orlando, L; Schiavone, P | 1 |
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| Duan, W; Kong, WM; Miao, JW; Su, L; Wang, T; Wang, Y; Wu, YM | 1 |
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| Merkley, CM; Tannock, IF; Winocur, G; Wojtowicz, JM | 1 |
| Allorge, D; Barthelemy, C; Bonnabry, P; Décaudin, B; Humbert, L; Lebecque, M; Odou, P; Pinturaud, M; Richeval, C; Sidikou, O; Simon, N; Soichot, M; Vasseur, M | 1 |
| Agrawal, A; Agrawal, S; Hossain, MM; Weber, GF; Zduniak, K; Ziolkowski, P | 1 |
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| Lam, HB; Yen, CF | 1 |
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| Anderson, H; Holmberg, E; Holmberg, L; Karlsson, P; Killander, F; Lundstedt, D; Malmström, P; Mattsson, J | 1 |
| Gao, B; Guo, LJ; Hao, S; Jiang, Y; Luo, DL; Tian, WG; Zhang, S; Zhang, XH | 1 |
| Chang, CL; Chen, JH; Chen, TM; Lai, MT; Lee, FP; Lin, KC; Wu, CC; Wu, SY; Yen, YC; Yuan, KS | 1 |
| Bondarenko, NA; Kabakov, AV; Kazakov, OV; Konenkov, VI; Lykov, AP; Poveshchenko, AF; Poveshchenko, OV; Raiter, TV; Strunkin, DN | 1 |
| Darko, KO; He, C; Huang, Y; Liu, Z; Peng, M; Su, Q; Tao, T; Yang, X; Yin, T | 1 |
| Ishchenko, IY; Kabakov, AV; Kazakov, OV; Konenkov, VI; Michurina, SV; Poveshchenko, AF; Raiter, TV; Strunkin, DN | 1 |
| Aalders, K; Bartlett, JMS; Biganzoli, L; Bogaerts, J; Cameron, D; De Valk, B; Khaled, H; Marreaud, S; Tryfonidis, K; Vermorken, J; Welnicka-Jaskiewicz, M | 1 |
| Antognelli, C; Crinò, L; Eliana, R; Floriani, I; Foglietta, J; Gori, S; Ludovini, V; Minenza, E; Nocentini, G; Piattoni, S; Pistola, L; Rulli, A; Sidoni, A; Talesa, VN; Tofanetti, FR; Tonato, M | 1 |
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| Abu-Hijlih, R; Al Mousa, A; Ismael, T; Mohamad, I; Mula-Hussain, L; Salem, A; Sultan, I | 1 |
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| Białk-Bielińska, A; Mulkiewicz, E; Stepnowski, P; Stokowski, M; Stolte, S | 1 |
| Asara, JM; Ben-Sahra, I; Hoxhaj, G; Hughes-Hallett, J; Ilagan, E; Manning, BD; Timson, RC; Yuan, M | 1 |
| Berman, H; Binns, MA; Henkelman, M; Nguyen, M; Piquette-Miller, M; Sekeres, MJ; Tannock, IF; van Eede, M; Winocur, G; Wojtowicz, JM; Yu, J; Zhang, H | 1 |
| Ishchenko, IY; Kabakov, AV; Kazakov, OV; Konenkov, VI; Lykov, AP; Michurina, SV; Poveshchenko, AF; Raiter, TV; Strunkin, DN | 1 |
| Wang, CH; Zhan, W | 1 |
| Fuller, S; Ghanbari, HA; Jiang, ZG; Shevtsova, O; Winocur, G; Wojtowicz, JM | 1 |
| Chen, J; Gao, J; Gong, W; Li, X; Wu, Z; Yue, K | 1 |
| Chernobrovkin, A; Pirmoradian, M; Sabatier, P; Saei, AA; Tokat, ÜG; Zubarev, RA | 1 |
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| Buckingham, W; Ejlertsen, B; Eriksen, JO; Ferree, S; Hood, T; Jensen, MB; Lænkholm, AV; Nielsen, TO; Ram, N; Wehn, P | 1 |
| Eder-Czembirek, C; Kornek, G; Rechinger, S; Seemann, R; Selzer, E | 1 |
| Kabakov, AV; Kazakov, OV; Konenkov, VI; Lykov, AP; Poveshchenko, AF; Poveshchenko, OV; Raiter, TV; Strunkin, DN | 1 |
| Avci, P; Bánvölgyi, A; Fésűs, L; Gyöngyösi, N; Kiss, N; Lee, G; Lőrincz, K; Szakonyi, J; Wikonkál, N | 1 |
| Ajona, D; Calvo, A; Cirauqui, C; de Aberasturi, AL; de Andrea, C; Exposito, F; Guruceaga, E; Montuenga, LM; Pio, R; Redin, E; Redrado, M; Vicent, S; Villalba, M | 1 |
| Albain, KS; Ambrosone, CB; Barlow, WE; Ergas, IJ; Hayes, DF; Hortobagyi, GN; Hutchins, LF; Kadlubar, SA; Kushi, LH; Kwan, ML; Larsen, V; Liu, S; Lyss, AP; Martino, S; Osborne, CK; Rae, JM; Ravdin, PM; Roh, JM; Yang, JJ; Yao, S; Yeh, IT; Zhu, Q | 1 |
| Liu, H; Tan, Q; Wu, C; Yu, S | 1 |
| Arai, H; Boku, N; Fukuda, N; Hironaka, S; Iwasa, S; Kawahira, M; Masuishi, T; Minashi, K; Muro, K; Nakajima, TE; Takahari, D; Yasui, H | 1 |
| Doerfler, L; Hanke, CW | 1 |
| Berry, DA; Burstein, HJ; Carey, L; Cirrincione, CT; Cohen, HJ; Dressler, LG; Gralow, JR; Grenier, D; Hart, RD; Hudis, CA; Hurria, A; Jatoi, A; Kartcheske, PA; Kornblith, AB; Liu, H; Magrinat, G; Mahmood, AA; Mauer, AM; Muss, HB; Norton, L; Parker, BA; Partridge, AH; Perez, EA; Polley, MC; Sutton, LM; Theodoulou, M; Winer, EP; Wolff, AC | 1 |
| Dini, D; Rodriguez Y Baena, F; Zhan, W | 1 |
| Becker, G; Levêque, D | 1 |
| Beusch, CM; Gaetani, M; Lundström, SL; Sabatier, P; Saei, AA; Yang, Z; Zubarev, RA | 1 |
| Abrams, J; Albain, KS; Badve, SS; Berenberg, JL; Brufsky, AM; Dees, EC; Desbiens, C; Ellis, MJ; Geyer, CE; Goetz, MP; Goggins, TF; Gomez, HL; Gray, RJ; Hayes, DF; Kaklamani, VG; Keane, MM; Lively, T; Mahalcioiu, C; Makower, DF; Mayer, IA; Olson, JA; Paik, S; Reddy, PS; Saphner, TJ; Sledge, GW; Sparano, JA; Toppmeyer, DL; Wagner, LI; Wood, WC | 1 |
| Hirafuji, M; Iizuka, K; Machida, M; Machida, T; Ohno, M; Shiga, S | 1 |
| Zhan, W | 1 |
| Alexander, T; Allen, AR; Anderson, JE; Groves, T; Kiffer, F; McElroy, T; Trujillo, M | 1 |
| Baldi, I; Bignon, E; Canal-Raffin, M; Martinez, B; Mathoulin-Pelissier, S; Molimard, M; Rouyer, M; Verdun-Esquer, C; Villa, A | 1 |
| Bojko, A; Charzynska, A; Czarnecka-Herok, J; Dabrowski, M; Sikora, E | 1 |
| Agrawal, RK; Ahmed, I; Bishop, J; Bowden, SJ; Brookes, CL; Brunt, AM; Canney, P; Churn, M; Dunn, J; Fernando, IN; Goodman, A; Grieve, R; Herring, K; Latief, TN; Marshall, A; Poole, CJ; Rea, DW; Ritchie, D; Spooner, D; Stevens, A | 1 |
| Komori, K; Kurata, T; Minami, K; Nakamura, T; Saito, S; Sakashita, K; Uchida, E; Watanabe, T; Yanagisawa, R | 1 |
| Ahn, MJ; Auclair, V; Berrocal, A; Bertolini, F; Castro, G; Cheung, WY; Chirovsky, D; Grünwald, V; Guillaume, X; Harrington, K; Joo, S; Kuyas, H; Shah, R; Sjoquist, K; Yang, MH | 1 |
| Nash, MA | 1 |
| Hasan, T; Maytin, EV | 1 |
| Bussières, JF; Caron, N; Delisle, JF; Dufour, A; Gagné, S; Mercier, G; Palamini, M; Therrien, R | 1 |
| Chen, M; Chen, S; Fan, Z; Hou, Z; Ke, S; Li, Y; Tian, H; Wang, F; Zhu, F | 1 |
| Bogachev, SS; Kabakov, AV; Kazakov, OV; Konenkov, VI; Lykov, AP; Poveshchenko, AF; Raiter, TV; Strunkin, DN | 1 |
| Mohammed, AM; Osman, SK; Saleh, KI; Samy, AM | 1 |
| Bago-Horvath, Z; Balic, M; Filipits, M; Gnant, M; Greil, R; Hulla, W; Kwasny, W; Lax, SF; Rudas, M; Singer, CF | 1 |
| -Maniglia, JV; Biselli-Chicote, PM; Goloni-Bertollo, EM; Maniglia, MP; Oliveira-Cucolo, JG; Pavarino, ÉC; Rodrigues-Fleming, GH; Russo, A | 1 |
| Biganzoli, E; Clatot, F; Crown, J; de Azambuja, E; De Bortoli, D; Demicheli, R; Desmedt, C; Di Leo, A; Fornili, M; Francis, PA; Piccart, M; Sotiriou, C; Viale, G | 1 |
| Hoegler, KM; Schleichert, RA | 1 |
| Elston, DM | 1 |
| Akiyama, F; Inaji, H; Kurosumi, M; Masuda, N; Ohashi, Y; Ohno, S; Ohsumi, S; Saji, S; Sato, N; Shimomura, A; Takao, S; Tokuda, Y; Tsuda, H; Watanabe, T | 1 |
| Germann, A; Januschowski, K; Julich-Haertel, H; Rickmann, A; Schulz, A; Szurman, P; von Briesen, H | 1 |
| André, C; Gagné, F; Gagnon, C; Kleinert, C; Poirier-Larabie, S | 1 |
| Białk-Bielińska, A; Dołżonek, J; Markiewicz, K; Stepnowski, P; Łukaszewicz, P | 1 |
| Baldi, I; Bignon, E; Canal-Raffin, M; Lassalle, R; Martinez, B; Mathoulin-Pelissier, S; Molimard, M; Rouyer, M; Sakr, D; Verdun-Esquer, C; Villa, A | 1 |
| Abdellatif, AAH; Aldubayan, MA; Alghenaim, FA; Alhowail, AH; Almogbel, YS; Alsalehi, NF; Felemban, SG | 1 |
| Banda, K; Gadi, VK; Indorf, A; Jung, L; Miske, A; Nelson, K | 1 |
| Abdellatif, AAH; Aldubayan, MA; Alhowail, AH; Almami, IS; Almogbel, YS | 1 |
| Banerjee, S; Datta, S; Jahnavi, J; Maity, TR; Samanta, A | 1 |
| Goel, N; Kumar, N | 1 |
| Abdellatif, AAH; Aldubayan, MA; Alhowail, AH; Almogbel, YS; Chigurupati, S; Nemala, RA | 1 |
| Dmytruk, SM; Gula, VI; Korenkov, OV; Pernakov, MS; Ponurko, AA; Riabenko, ТV; Yarmolenko, OS | 1 |
| Abdelmeniem, IM; El Eryan, IM; Fouda, I; Nofal, A; Omar, SS | 1 |
| Guan, Z; Li, S; Liang, Y; Niu, B; Wang, J; Wang, X; Yang, A; Yu, J; Zhu, Z | 1 |
| Bonnabry, P; Fleury-Souverain, S; Guillarme, D; Maurin, J; Rudaz, S | 1 |
| Dahlgren, D; Hellström, PM; Kullenberg, F; Lennernäs, H; Nygren, P; Peters, K; Rosenqvist, E; Sjöblom, M | 1 |
| Agarwal, N; Bhurani, D; Hoda, U; Khan, MA; Sehar, N | 1 |
| Cirillo, N; Huang, J; Hwang, AYM; Iskandar, M; Jia, Y; Kim, B; Mohammed, AI | 1 |
| Burger, E; Eggemann, H; Ignatov, A; Meinecke, AM; Schreiber, J | 1 |
| Cunningham, D; Starling, N | 1 |
| Bryszewska, M; de la Mata, FJ; Del Olmo, NS; Garcia-Gallego, S; Hołota, M; Ionov, M; Michlewska, S; Ortega, P | 1 |
| Agrawal, RK; Ahmed, I; Bowden, SJ; Brunt, AM; Canney, P; Churn, M; Fernando, IN; Lax, S; Rea, DW; Steven, JH; Stevens, A | 1 |
| da Cunha de Medeiros, P; Nascimento, CC; Perobelli, JE | 1 |
| Bonvin, AM; Gahtory, D; Javed, A; Klumperman, J; Koukos, PI; Maas, PE; Maurice, MM; Mol, JA; Schwarz, LL; Shukla, R; Strous, GJ; Timmermans-Sprang, EP; van den Nieuwboer, M; van der Krift, F; van der Stelt, M; Veldhuizen, EJ; Vermeulen, M; Weingarth, M; Zijlmans, DW | 1 |
| Ahmed, OM; El-Sherbiny, IM; Fytory, M; Mansour, A; Rahman, FESA | 1 |
373 review(s) available for fluorouracil and methotrexate
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Quinolone hybrids and their anti-cancer activities: An overview.
Topics: Animals; Antineoplastic Agents; Humans; Neoplasms; Quinolones; Structure-Activity Relationship | 2019 |
Coumarin-containing hybrids and their anticancer activities.
Topics: Animals; Antineoplastic Agents; Coumarins; Drug Design; Drug Discovery; Humans; Neoplasms; Structure-Activity Relationship | 2019 |
Current concepts of chemotherapy combined with other modalities for head and neck cancer.
Topics: Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Immunotherapy; Laryngeal Neoplasms; Leucovorin; Methotrexate; Neoplasm Metastasis; Neoplasms; Radiotherapy; Vinblastine | 1975 |
The integration of chemotherapy into a combined modality approached to cancer therapy. V. Squamous cell cancer of the head and neck.
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Laryngeal Neoplasms; Leucovorin; Lip Neoplasms; Lymphatic Metastasis; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Tongue Neoplasms | 1975 |
Therapeutic approaches in malignant mesothelioma.
Topics: Alkylating Agents; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Gold Colloid, Radioactive; Humans; Mesothelioma; Methotrexate; Nitrogen Mustard Compounds; Palliative Care; Peritoneal Neoplasms; Phosphorus Radioisotopes; Pleural Neoplasms; Radiotherapy Dosage; Thiotepa | 1977 |
The integration of chemotherapy into combined modality treatment of solid tumors. VIII. Cervical cancer.
Topics: Alkylating Agents; Altretamine; Antineoplastic Agents; Bleomycin; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Radiotherapy, High-Energy; Radium; Uterine Cervical Neoplasms; Vaginal Smears | 1977 |
The chemotherapy of head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1977 |
Antineoplastic drugs: clinical pharmacology and therapeutic use.
Topics: Alkaloids; Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Azacitidine; Bleomycin; Cisplatin; Cyclophosphamide; Cytarabine; Drug Interactions; Fluorouracil; Humans; Kinetics; Methotrexate; Podophyllotoxin | 1978 |
The clinical pharmacology of antineoplastic agents (first of two parts).
Topics: Animals; Antineoplastic Agents; Asparaginase; Binding Sites; Biological Transport; Chemical and Drug Induced Liver Injury; Depression, Chemical; DNA, Neoplasm; Drug Interactions; Drug Resistance; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Kidney Diseases; Liver; Lung Diseases; Methotrexate; Mice; Neoplasms; Tetrahydrofolate Dehydrogenase | 1975 |
Chemotherapy in the treatment of malignant brain tumors.
Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cyclophosphamide; Disease Models, Animal; Drug Evaluation; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Nitrogen Mustard Compounds; Nitrosourea Compounds; Plicamycin; Podophyllotoxin; Procarbazine; Vincristine | 1975 |
Therapeutic approaches to hepatoma.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Catheterization; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Neoplasm Metastasis; South Africa | 1975 |
Chemotherapy of solid tumors. Recent advances.
Topics: Adult; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Child; Cyclophosphamide; Doxorubicin; Drug Combinations; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunotherapy; Leucovorin; Male; Melphalan; Methotrexate; Neoplasm Metastasis; Neoplasms; Osteosarcoma; Prednisone; Rhabdomyosarcoma; Testicular Neoplasms; Thiotepa; Vinblastine; Vincristine | 1976 |
[The state of hormone and chemotherapy in breast neoplasms].
Topics: Androgens; Brain Neoplasms; Breast Neoplasms; Castration; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Estrogens; Female; Fluorouracil; Humans; Hypophysectomy; Lymphatic Metastasis; Methotrexate; Neoplasm Metastasis; Prednisone; Progesterone; Receptors, Cell Surface | 1978 |
Chemotherapy for breast cancer.
Topics: Adult; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; National Institutes of Health (U.S.); Prednisone; Receptors, Cell Surface; United States | 1979 |
Immunologic aspects of cancer chemotherapy.
Topics: Animals; BCG Vaccine; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Immunotherapy; Levamisole; Mercaptopurine; Methotrexate; Mice; Neoplasms; Propionibacterium acnes; Vinca Alkaloids | 1977 |
The chemotherapy of advanced bladder carcinoma.
Topics: Antineoplastic Agents; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Injections, Intra-Arterial; Methotrexate; Mitomycins; Neoplasm Metastasis; Recurrence; Research Design; Urinary Bladder Neoplasms | 1977 |
Chemotherapy of advanced soft-tissue sarcomas in adults.
Topics: Adult; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Cyclophosphamide; Dacarbazine; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Immunotherapy; Methotrexate; Neoplasm Metastasis; Sarcoma; Soft Tissue Neoplasms; Vincristine | 1977 |
[Hormone and chemotherapy of breast carcinoma].
Topics: Androgens; Breast Neoplasms; Castration; Cyclophosphamide; Drug Therapy, Combination; Estrogens; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Metastasis; Progestins | 1977 |
Individual cell biology: basis and prospects for a rational cancer chemotherapy.
Topics: Adenocarcinoma; Brain Neoplasms; Breast Neoplasms; Cell Cycle; Chromosome Aberrations; Cyclophosphamide; Dactinomycin; DNA, Neoplasm; Drug Resistance; Drug Therapy, Combination; Female; Fluorouracil; Fructose-Bisphosphate Aldolase; Humans; Isoenzymes; Kinetics; Male; Methotrexate; Neoplasm Staging; Neoplasms; Prognosis | 1977 |
[Adjuvant (preventive) postoperative chemotherapy in breast carcinoma].
Topics: Breast Neoplasms; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; Humans; Melphalan; Menopause; Methotrexate; Postoperative Care | 1978 |
Are surgical adjuvant trials altering the course of breast cancer?
Topics: Adult; Aged; Antineoplastic Agents; BCG Vaccine; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovary; Receptors, Estrogen | 1978 |
The fluoropyrimidines: biochemical mechanisms and design of clinical trials.
Topics: Antineoplastic Agents; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Metabolism; Methotrexate; Pyrimidines; Thymidine; Thymine | 1978 |
Chemotherapy in the management of invasive bladder cancer. A review.
Topics: Adult; Aged; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mitomycins; Urinary Bladder Neoplasms | 1979 |
Chemotherapy of ovarian cancer.
Topics: Alkylating Agents; Altretamine; Cisplatin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms | 1978 |
The effects of cancer chemotherapeutic agents on normal hematopoietic precursor cells: a review.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Asparaginase; Benzamides; Busulfan; Carmustine; Cisplatin; Cyclophosphamide; Cytarabine; Drug Evaluation, Preclinical; Erythrocytes; Fluorouracil; Hematopoietic Stem Cells; Humans; Hydroxyurea; Lomustine; Methotrexate; Nitrogen Mustard Compounds; Spleen; Vinca Alkaloids | 1976 |
Selective suppression of humoral immunity by antineoplastic drugs.
Topics: Animals; Antineoplastic Agents; Binding Sites; Chickens; Cyclophosphamide; Cytarabine; Fluorouracil; Guinea Pigs; Humans; Immunity; Immunity, Cellular; Immunosuppressive Agents; Leucovorin; Male; Mercaptopurine; Methotrexate; Mice; Neoplasms; Piperazines; Rats; Stimulation, Chemical | 1976 |
The treatment of plasma cell myeloma.
Topics: Animals; Carmustine; Cytarabine; Doxorubicin; Drug Evaluation, Preclinical; Fluorouracil; Humans; Melphalan; Methotrexate; Mice; Mice, Inbred BALB C; Multiple Myeloma; Myeloma Proteins; Prednisone; Procarbazine; Remission, Spontaneous | 1976 |
[Side effects of cytotoxic drugs on the nervous system].
Topics: Antineoplastic Agents; Asparaginase; Fluorouracil; Humans; Methotrexate; Nervous System; Procarbazine; Vinblastine; Vincristine | 1976 |
Experimental investigations on immunodepressive properties of carcinogenic substances in male Sprague-Dawley rats.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antibody Formation; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinogens; Cyclophosphamide; Fluorouracil; Immunosuppression Therapy; Male; Mercaptopurine; Methotrexate; Neoplasms, Experimental; Nitrosamines; Nitroso Compounds; Rats; Spleen | 1975 |
Biochemical markers in cancer of the breast.
Topics: Breast Neoplasms; Cadaverine; Carcinoembryonic Antigen; Chorionic Gonadotropin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Guanosine; Humans; Inosine; Methotrexate; Neoplasm Metastasis; Prognosis; Putrescine; Recurrence; Spermidine; Spermine | 1976 |
The role of chemotherapy in the treatment of cancer of the breast.
Topics: Breast Neoplasms; Castration; Cyclophosphamide; Drug Resistance; Estrogens; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Prednisone; Thiotepa | 1975 |
Chemotherapy of ovarian cancer: past and present.
Topics: Acrylates; Alkylating Agents; Altretamine; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Maryland; Methotrexate; Ovarian Neoplasms; Porfiromycin; Procarbazine; Progestins | 1975 |
Psoriasis: a review. II.
Topics: Adrenal Cortex Hormones; Anthralin; Azathioprine; Azauridine; Fluorouracil; Humans; Hydroxyurea; Lomustine; Mechlorethamine; Methotrexate; Psoriasis; Tars; Tretinoin; Ultraviolet Therapy | 1975 |
[Neurological disorders induced by antineoplastic drugs].
Topics: Animals; Antineoplastic Agents; Cell Division; Cisplatin; Fluorouracil; Humans; Methotrexate; Nervous System; Nervous System Diseases; Vincristine | 1992 |
Treating the relapsed patient.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Recurrence, Local; Salvage Therapy; Survival Rate | 1992 |
Chemotherapeutic strategies in metastatic colorectal cancer: an overview of current clinical trials.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cisplatin; Clinical Trials as Topic; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intravenous; Interferons; Leucovorin; Methotrexate; Phosphonoacetic Acid | 1992 |
Current role of chemotherapy in head and neck cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis; Randomized Controlled Trials as Topic | 1992 |
Hypersensitivity reactions.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Aziridines; Benzoquinones; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide; Cytarabine; Dacarbazine; Drug Hypersensitivity; Etoposide; Fluorouracil; Humans; Ifosfamide; Melphalan; Methotrexate; Mitomycins; Neoplasms; Paclitaxel; Pentostatin; Procarbazine; Teniposide | 1992 |
Antimetabolites.
Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; Drug Interactions; Drug Resistance; Fluorouracil; Humans; Mercaptopurine; Methotrexate; Thioguanine | 1992 |
Antimetabolites.
Topics: Animals; Cytarabine; Drug Interactions; Drug Resistance; Fluorouracil; Humans; Methotrexate; Neoplasms | 1992 |
[Effect of antifolates and folates on the antineoplastic action of fluoropyrimidines].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Interactions; Fluorouracil; Humans; In Vitro Techniques; Leucovorin; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental | 1992 |
Chemotherapy in head and neck cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Remission Induction; Survival Analysis; Treatment Outcome | 1992 |
Chemotherapy for muscle-infiltrating bladder cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Fluorouracil; Humans; Methotrexate; Phosphoramide Mustards; Urinary Bladder Neoplasms; Vinblastine | 1992 |
High-dose fluorouracil: a new perspective in the treatment of colorectal cancer?
Topics: Clinical Trials as Topic; Dose-Response Relationship, Drug; Fluorouracil; Half-Life; Humans; Leucovorin; Methotrexate | 1992 |
Biochemical modulation of fluorouracil by dipyridamole: preclinical and clinical experience.
Topics: Colonic Neoplasms; Deoxyuridine; Dipyridamole; DNA Damage; DNA, Neoplasm; Drug Interactions; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Methotrexate; Nucleosides; Nucleotides; RNA, Neoplasm; Thymidine; Tumor Cells, Cultured; Uridine Monophosphate | 1992 |
Evolving concepts in the systemic adjuvant treatment of breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Prognosis; Tamoxifen | 1992 |
[Systemic chemotherapy in metastatic colorectal adenocarcinomas].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neoplasms; Female; Fluorouracil; Humans; Interferon-alpha; Leucovorin; Liver Neoplasms; Male; Methotrexate; Mitomycin; Nitrosourea Compounds; Pyrimidines; Semustine | 1992 |
Cytotoxic treatment of metastatic breast cancer. Which drugs and drug combinations to use?
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Epirubicin; Etoposide; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Mitomycin; Mitoxantrone; Neoplasm Metastasis; Vincristine | 1992 |
[Biochemical modulation--the historical background].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Fluorouracil; Humans; Leucovorin; Methotrexate; Stomach Neoplasms | 1992 |
[Advances in the treatment of advanced colorectal cancer].
Topics: Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neoplasms; Drug Interactions; Fluorouracil; Humans; Interferons; Interleukin-2; Leucovorin; Methotrexate; Neoplasm Staging; Purines | 1990 |
Chemotherapy for glioblastoma multiforme.
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cisplatin; Fluorouracil; Humans; Methotrexate; Nursing Assessment | 1991 |
Antimetabolites.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Cytarabine; Cytidine; Drug Interactions; Drug Resistance; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms | 1991 |
Single-agent chemotherapy for nonmetastatic gestational trophoblastic neoplasia. Perspectives for the 21st century after three decades of use.
Topics: Chorionic Gonadotropin; Dactinomycin; Etoposide; Female; Fluorouracil; Humans; Methotrexate; Pregnancy; Prognosis; Severity of Illness Index; Trophoblastic Neoplasms; Uterine Neoplasms | 1991 |
Sequential methotrexate/5-fluorouracil in advanced colorectal cancer treatment.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Methotrexate; Time Factors | 1991 |
Chemoprotectants for cancer chemotherapy.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Cisplatin; Cyclophosphamide; Fluorouracil; Humans; Ifosfamide; Leucovorin; Mesna; Methotrexate; Neoplasms; Razoxane; Sulfhydryl Compounds; Uridine | 1991 |
Hexamethylmelamine (altretamine): early National Cancer Institute trials.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; National Institutes of Health (U.S.); Neoplasm Staging; Ovarian Neoplasms; United States | 1991 |
Altretamine.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Interactions; Female; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Ovarian Neoplasms | 1991 |
Chemotherapy of advanced cancer of the colon and rectum.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic Neoplasms; Fluorouracil; Humans; Leucovorin; Methotrexate; Phosphonoacetic Acid; Rectal Neoplasms | 1991 |
Levamisole in the adjuvant treatment of colon cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Intestinal Absorption; Levamisole; Methotrexate | 1991 |
Biochemical modulation of 5-fluorouracil.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorouracil; Humans; Leucovorin; Methotrexate; Neoplasm Metastasis; Remission Induction | 1990 |
Modulation of cytotoxic drug activity by dipyridamole.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Cytarabine; Dipyridamole; Drug Interactions; Etoposide; Fluorouracil; Humans; Leucovorin; Methotrexate | 1990 |
Adjuvant therapy in breast cancer.
Topics: Adjuvants, Pharmaceutic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Prednisone; Tamoxifen; Vincristine | 1990 |
[Dose intensity in cancer chemotherapy in gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Humans; Methotrexate; Mitomycin; Mitomycins; Stomach Neoplasms; Suppositories; Tegafur | 1990 |
Modulation of 5-fluorouracil efficacy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Evaluation; Fluorouracil; Humans; Leucovorin; Methotrexate; Neoplasms | 1990 |
The treatment of psoriasis.
Topics: Administration, Oral; Administration, Topical; Anthralin; Anti-Inflammatory Agents; Bed Rest; Chronic Disease; Coal Tar; Combined Modality Therapy; Emollients; Fluorouracil; Glucocorticoids; Humans; Mechlorethamine; Methotrexate; Patient Acceptance of Health Care; Phototherapy; Psoriasis; Retinoids; Ultraviolet Therapy | 1990 |
Drug level monitoring: cytostatics.
Topics: Alkylating Agents; Aminoacridines; Amsacrine; Anthraquinones; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Bleomycin; Busulfan; Chlorambucil; Chromatography, Gas; Chromatography, Liquid; Cisplatin; Cyclophosphamide; Cytarabine; Fluorouracil; Humans; Mass Spectrometry; Melphalan; Methotrexate; Mitomycins; Monitoring, Physiologic; Nitrosourea Compounds; Podophyllotoxin; Purines; Thiotepa; Vinca Alkaloids | 1985 |
Intracavitary chemotherapy.
Topics: Absorption; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Bacterial Infections; Bleomycin; Cisplatin; Cytarabine; Diffusion; Doxorubicin; Drug Synergism; Female; Fluorouracil; Humans; Immunotherapy; Melphalan; Methotrexate; Mitomycins; Neoplasms; Ovarian Neoplasms; Peritoneal Cavity; Permeability; Pleura; Pleural Effusion; Radiation-Sensitizing Agents; Sclerosis; Streptozocin | 1985 |
Combination of chemotherapy with radiotherapy: review of previous studies and new perspectives.
Topics: Antineoplastic Agents; Bleomycin; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Radiation-Sensitizing Agents | 1985 |
Update in cancer chemotherapy, Part III: Lung cancer, Part 1.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Dactinomycin; Doxorubicin; Fluorouracil; Humans; Lomustine; Lung Neoplasms; Mechlorethamine; Methotrexate; Mitomycin; Mitomycins; Neoplasm Staging; Peptichemio; Prednisone; Procarbazine; Prognosis; Vincristine | 1985 |
Corticosteroid drugs: their role in oncological practice.
Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms; Cyclophosphamide; Dacarbazine; Doxorubicin; Drug Therapy, Combination; Dyspnea; Fluorouracil; Hodgkin Disease; Humans; Hypercalcemia; Leukemia; Leukemia, Lymphoid; Lymphoma; Mechlorethamine; Melphalan; Methotrexate; Multiple Myeloma; Palliative Care; Prednisone; Procarbazine; Receptors, Glucocorticoid; Vinblastine; Vincristine; Vomiting | 1986 |
Sequential chemotherapy with methotrexate and 5-fluorouracil: mechanism of synergistic effect.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Methotrexate; Neoplasms; Purines; RNA | 1986 |
Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neoplasms; Drug Interactions; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Methotrexate; Palliative Care; Quality of Life; Random Allocation | 1989 |
Antimetabolites.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Mercaptopurine; Methotrexate; Purines; Thioguanine | 1987 |
Antimetabolites.
Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; Fluorouracil; Humans; Leucovorin; Methotrexate | 1989 |
Adjuvant chemotherapy for node-negative breast cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymph Nodes; Mastectomy; Menopause; Methotrexate; Prospective Studies; Randomized Controlled Trials as Topic; Receptors, Estrogen; Thiotepa; Vincristine | 1989 |
New vistas for leucovorin in cancer chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemical Phenomena; Chemistry; Fluorouracil; Humans; Leucovorin; Methotrexate; Neoplasms | 1989 |
Karnofsky memorial lecture. Conceptual and practical advances in the management of breast cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate | 1989 |
Enhancement of 5-fluorouracil antitumor effects by the prior administration of methotrexate.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Fluorouracil; Humans; Methotrexate | 1989 |
[Chemotherapy of prostatic cancer].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dacarbazine; Diethylstilbestrol; Doxorubicin; Estramustine; Fluorouracil; Humans; Hydroxyurea; Male; Melphalan; Methotrexate; Mitomycin; Mitomycins; Prednisolone; Procarbazine; Prostatic Neoplasms; Streptozocin; Vincristine | 1985 |
Cytostatic drug therapy in disseminated colorectal cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Floxuridine; Fluorouracil; Humans; Leucovorin; Methotrexate; Semustine; Vincristine | 1988 |
Combined therapy in advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Estrogens, Conjugated (USP); Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Tamoxifen | 1985 |
Chemotherapy of primary brain tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Eflornithine; Ependymoma; Fluorouracil; Glioblastoma; Humans; Hydroxyurea; Lomustine; Medulloblastoma; Methotrexate; Mitoguazone; Mitolactol; Neoplasm Recurrence, Local; Ornithine; Prednisone; Risk; Thioguanine; Vincristine | 1985 |
Systemic cytostatic drug therapy in liver cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Clinical Trials as Topic; Colonic Neoplasms; Doxorubicin; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Methotrexate; Rectal Neoplasms; Semustine; Vincristine | 1986 |
Treatment of advanced breast cancer with chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Prednisone; Vincristine | 1988 |
Principles of brain tumor chemotherapy.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Carbon Radioisotopes; Carmustine; Cell Line; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance; Fluorouracil; Glioma; Humans; Hydroxyurea; Infusions, Intra-Arterial; Karyotyping; Kinetics; Mannitol; Methotrexate; Podophyllotoxin; Procarbazine; Rats; Tumor Stem Cell Assay | 1986 |
The routinization of intraperitoneal (intracavitary) chemotherapy and immunotherapy.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Fluorouracil; Hot Temperature; Humans; Hydrogen-Ion Concentration; Immunotherapy; In Vitro Techniques; Infusions, Parenteral; Methotrexate; Parenteral Nutrition, Total; Peritoneal Cavity; Peritoneal Neoplasms | 1986 |
Oncogenic transformation of C3H/10T1/2 Cl 8 mouse embryo fibroblasts by inhibitors of nucleotide metabolism.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Cytidine; Deoxycytidine; Deoxyribonucleotides; DNA; Embryo, Mammalian; Fibroblasts; Floxuridine; Fluorouracil; Idoxuridine; Methotrexate; Mice; Mice, Inbred C3H; Mutation; Thymidine; Trifluridine | 1985 |
[Current studies of sequential methotrexate and 5-fluorouracil treatment in cancer chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Fluorouracil; Humans; Methotrexate; Rectal Neoplasms; Stomach Neoplasms | 1988 |
Role of thymidine in biochemical modulation: a review.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cytarabine; Deoxycytidine Kinase; DNA Replication; DNA, Neoplasm; Drug Evaluation; Drug Synergism; Fluorouracil; Folic Acid Antagonists; Humans; Interphase; Kinetics; Leukemia; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Nucleic Acid Synthesis Inhibitors; Nucleotides; Phosphonoacetic Acid; RNA, Neoplasm; Species Specificity; Thymidine | 1987 |
Biochemical modulation of fluorouracil therapy in advanced colorectal cancer.
Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Interactions; Fluorouracil; Humans; Methotrexate; Rectal Neoplasms | 1987 |
Breast cancer 1985. What have we learned?
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Neoplasm Staging; Ovariectomy; Tamoxifen; Time Factors | 1986 |
Unresolved issues in combination chemotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Carmustine; Cell Cycle; Cyclophosphamide; Dacarbazine; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Drug Synergism; Fluorouracil; Humans; Leukemia, Experimental; Metabolic Clearance Rate; Methotrexate; Neoplasm Transplantation | 1986 |
Biochemical modulation: application of laboratory models to the clinic.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cytarabine; Dose-Response Relationship, Drug; Drug Evaluation; Fluorouracil; Humans; Methotrexate; Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid; Thymidine | 1986 |
Carcinoma of eccrine sweat gland: experience with chemotherapy, autopsy findings in a patient with metastatic eccrine carcinoma, and a review of the literature.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dacarbazine; Eccrine Glands; Fluorouracil; Humans; Male; Methotrexate; Sweat Gland Neoplasms; Sweat Glands | 1986 |
Chemotherapy of brain tumors: physiological and pharmacokinetic considerations.
Topics: Antineoplastic Agents; Autoradiography; Biological Transport; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Carmustine; Fluorouracil; Humans; Kinetics; Methotrexate; Tomography, Emission-Computed; Tomography, X-Ray Computed | 1986 |
Prednimustine in advanced breast cancer: a review.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Leukocyte Count; Melphalan; Methotrexate; Prednimustine; Time Factors | 1986 |
Intraperitoneal chemotherapy: a review.
Topics: Abdominal Neoplasms; Antineoplastic Agents; Cisplatin; Clinical Trials as Topic; Cytarabine; Doxorubicin; Evaluation Studies as Topic; Fluorouracil; Humans; Injections, Intraperitoneal; Liver; Mathematics; Melphalan; Methotrexate; Peritoneum | 1986 |
Controversies in the treatment of cancer of the breast.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Ovary; Prednisone | 1987 |
Adjuvant systemic therapy for resectable breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Castration; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Immunotherapy; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Prognosis; Research Design; Tamoxifen | 1985 |
Adjuvant therapy in primary breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Hospitalization; Humans; Lymph Nodes; Melphalan; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Random Allocation; Tamoxifen; Time Factors; United States; Vincristine | 1985 |
Patterns of metastasis and natural courses of breast carcinoma.
Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Receptors, Estrogen; Recurrence | 1985 |
[Chemotherapy of cancer of the large intestine].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colonic Neoplasms; Drug Evaluation; Fluorouracil; Humans; Lomustine; Melphalan; Methotrexate; Rectal Neoplasms; Semustine; Vincristine | 1985 |
[Current views of the treatment of non-microcellular carcinoma of the lungs].
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Evaluation Studies as Topic; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Mitomycins; Peptichemio; Pneumonectomy; Procarbazine; Radiotherapy Dosage; Vincristine | 1985 |
Neurologic complications of systemic cancer.
Topics: Arachnoid; Bacterial Infections; Brain; Brain Neoplasms; Cerebrovascular Disorders; Cisplatin; Disseminated Intravascular Coagulation; Electroencephalography; Endocarditis; Fluorouracil; Humans; Lung Neoplasms; Melanoma; Meningeal Neoplasms; Methotrexate; Neoplasms; Nervous System Diseases; Paraneoplastic Syndromes; Pia Mater; Prognosis; Spinal Cord Compression; Spinal Cord Neoplasms; Tomography, X-Ray Computed; Vinca Alkaloids | 1985 |
Hormono-chemotherapy in the treatment of advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Hormones; Humans; Menopause; Methotrexate; Middle Aged; Prednisone; Random Allocation; Vincristine | 1985 |
Breast cancer chemotherapy: perioperative considerations in breast reconstruction.
Topics: Adult; Alkylating Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Mastectomy; Melphalan; Methotrexate; Middle Aged; Prednisone; Surgery, Plastic; Tamoxifen; Thiotepa; Vincristine | 1985 |
Systemic adjuvant therapy and breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cost-Benefit Analysis; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Prednisone; Prognosis; Tamoxifen; Vincristine | 1985 |
Chemotherapy of brain tumors.
Topics: Adult; Antineoplastic Agents; Azaguanine; Bleomycin; Brain Neoplasms; Child; Cyclophosphamide; Drug Synergism; Fluorouracil; Glioblastoma; Glioma; Humans; Hydroxyurea; Medulloblastoma; Methotrexate; Nitrogen Mustard Compounds; Nitrosourea Compounds; Plicamycin; Procarbazine; Streptonigrin; Vinblastine; Vincristine | 1972 |
Chemotherapy in advanced ovarian cancer.
Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Cystadenocarcinoma; Cystadenoma; Drug Therapy, Combination; Endometriosis; Female; Fluorouracil; Humans; Laparoscopy; Mesonephroma; Methotrexate; Middle Aged; Ovarian Neoplasms; Palliative Care; Radiography | 1973 |
Drug reactions. XXIV. Cutaneous reactions to cytostatic agents.
Topics: Alopecia; Aminopterin; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Eruptions; Erythema; Fluorouracil; Gynecomastia; Humans; Hydroxyurea; Methotrexate; Photosensitivity Disorders; Pigmentation Disorders; Radiation Injuries; Stomatitis; Vinblastine | 1974 |
[Principles of the effect of cytostatics].
Topics: Antineoplastic Agents; Asparaginase; Cell Division; Chlorambucil; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Fluorouracil; Folic Acid Antagonists; Humans; Melphalan; Mercaptopurine; Methotrexate; Neoplasms; Triaziquone; Triethylenephosphoramide; Vincristine | 1974 |
The role of chemotherapy in the treatment of lung cancer.
Topics: Adenocarcinoma; Alkylating Agents; Antineoplastic Agents; Bleomycin; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Mitomycins; Nitrosourea Compounds; Thioguanine; Vinblastine; Vincristine | 1974 |
The prognosis and management of recurrent abdominal malignancies.
Topics: Abdominal Neoplasms; Adolescent; Adult; Antineoplastic Agents; Bile Duct Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Male; Mechlorethamine; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Palliative Care; Pancreatic Neoplasms; Prognosis; Rectal Neoplasms; Stomach Neoplasms; Thiotepa | 1969 |
Solid tumor chemotherapy: What have we to offer.
Topics: Adult; Antineoplastic Agents; Child; Cyclophosphamide; Dactinomycin; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Palliative Care; Thiotepa; Time Factors; Vincristine | 1970 |
[Drug therapy of cervical cancer].
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Drug Resistance; Drug Therapy; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic System; Mechlorethamine; Methotrexate; Mitomycins; Podophyllin; Preoperative Care; Thiotepa; Triaziquone; Uterine Cervical Neoplasms; Vinblastine | 1974 |
The chemical therapy of breast cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Castration; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Nitrogen Mustard Compounds; Prednisone; Thiotepa; Vinblastine; Vincristine | 1974 |
A review of chemotherapy in gastric cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Carmustine; Chlorambucil; Chromomycins; Cyclophosphamide; Cytarabine; Drug Evaluation; Drug Therapy, Combination; Floxuridine; Fluorouracil; Humans; Mechlorethamine; Methotrexate; Mitomycins; Nitrosourea Compounds; Olivomycins; Stomach Neoplasms | 1974 |
The use of cytotoxic drugs in the surgery of malignant disease.
Topics: Abdominal Neoplasms; Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Carcinoma, Basal Cell; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Dysgerminoma; Female; Fluorouracil; Head; Head and Neck Neoplasms; Hodgkin Disease; Humans; Injections, Intra-Arterial; Leg; Melanoma; Melphalan; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasms; Nitrogen Mustard Compounds; Pregnancy; Sarcoma; Sarcoma, Ewing; Skin Neoplasms; Vinblastine; Wilms Tumor | 1968 |
An assessment of massive-dose chemotherapy of malignant disease.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cell Division; Cyclophosphamide; Cytarabine; Female; Fluorouracil; Humans; Leukemia L1210; Leukemia, Lymphoid; Lymphoma; Melphalan; Mercaptopurine; Methotrexate; Mice; Multiple Myeloma; Neoplasms; Nitrogen Mustard Compounds; Prednisone; Pregnancy; Time Factors; Trophoblastic Neoplasms; Vinblastine | 1971 |
Current cancer chemotherapy in obstetrics and gynecology.
Topics: Alkaloids; Alkylating Agents; Anti-Bacterial Agents; Antimetabolites; Blood Cell Count; Bone Marrow; Chlorambucil; Computers; Cyclophosphamide; Dactinomycin; Diagnosis, Differential; DNA; Female; Fluorouracil; Genital Neoplasms, Female; Guanine; Hormones; Humans; Hydatidiform Mole; Mass Screening; Methotrexate; Microbial Sensitivity Tests; New York; Nitrogen Mustard Compounds; Ovarian Neoplasms; Pregnancy; Trophoblastic Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Vinblastine | 1971 |
[Molecular basis of the relation between the cytotoxic effect of antineoplastic compounds and the cell cycle phase].
Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Alkylating Agents; Androgens; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Culture Techniques; Cyclic AMP; Dactinomycin; DNA Replication; DNA, Neoplasm; Estrogens; Fluorouracil; Glucagon; Glucocorticoids; Mathematics; Methotrexate; Mitosis; Molecular Biology; Neoplasm Transplantation; Neoplasms, Experimental; Receptors, Drug; RNA, Neoplasm; Sarcoma, Experimental | 1972 |
Single and combination nonhormonal chemotherapy in breast cancer.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Drug Synergism; Female; Fluorouracil; Humans; Hydroxyurea; Melphalan; Menopause; Methotrexate; Mice; Vinblastine; Vincristine | 1972 |
The action of antimetabolites in the skin: methotrexate for psoriasis.
Topics: Carcinoma, Basal Cell; Cell Division; DNA; Fluorouracil; Humans; Injections, Intradermal; Keratosis; Methotrexate; Mitosis; Psoriasis; Skin Diseases; Tritium | 1972 |
Chemotherapy of bronchial carcinoma.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Blood Cell Count; Bone Marrow Diseases; Bronchial Neoplasms; Cyclophosphamide; Disease Models, Animal; Drug Combinations; Fluorouracil; Humans; Methotrexate; Pleural Effusion; Prognosis; Vascular Diseases; Vena Cava, Superior; Vincristine | 1973 |
The cell cycle and the development of pathology in the gastrointestinal tract.
Topics: Adenine; Animals; Autoradiography; Cell Count; Cell Division; Colon; Digestive System; DNA; Flucytosine; Fluorouracil; Humans; Intestine, Small; Methotrexate; Pentosyltransferases; RNA; Stomach; Thymidine; Thymidine Kinase; Tritium | 1972 |
Chemotherapy in colorectal cancer.
Topics: Carmustine; Chlorambucil; Colonic Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Nitrogen Mustard Compounds; Rectal Neoplasms; Vincristine | 1973 |
Neurotoxicity of commonly used antineoplastic agents (first of two parts).
Topics: Animals; Antineoplastic Agents; Asparaginase; Brain; Brain Diseases; Fluorouracil; Humans; Leukemia; Mental Disorders; Methotrexate; Nervous System; Nervous System Diseases; Neurologic Manifestations; Syndrome | 1974 |
Predictive tests in cancer. Tuesday 9 April 1974.
Topics: Age Factors; Breast Neoplasms; Cell Movement; Clinical Enzyme Tests; Colonic Neoplasms; Cytarabine; Diagnosis, Differential; Doxorubicin; Drug Combinations; Drug Evaluation; Drug Evaluation, Preclinical; Fluorouracil; Humans; Kinetics; Leukemia; Mercaptopurine; Methods; Methotrexate; Models, Chemical; Neoplasms; Prognosis; Sarcoma; Testosterone; Thioguanine | 1974 |
[Current status of cytostatic therapy].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Cytarabine; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Mitosis; Neoplasm Metastasis; Thymine Nucleotides | 1974 |
Present experiences with hepatic dearterialization in liver neoplasm.
Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Catheterization; Dactinomycin; Female; Fluorouracil; Hepatic Artery; Humans; Ligation; Lipids; Liver Circulation; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms, Experimental; Rats; Remission, Spontaneous | 1974 |
Single-agent therapy for Hodgkin's disease.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Carmustine; Chlorambucil; Cyclophosphamide; Dactinomycin; Evaluation Studies as Topic; Fluorouracil; Hodgkin Disease; Humans; Mechlorethamine; Mercaptopurine; Methotrexate; Prednisone; Procarbazine; Thiotepa; Vinblastine; Vincristine | 1973 |
Chemotherapy and the life cycle of leukaemic cells. A comparison between the growth characteristics of human acute leukaemia and the murine leukaemia L 1210.
Topics: Anilides; Animals; Cell Division; Cyclophosphamide; Cytarabine; DNA, Neoplasm; Fluorouracil; Humans; Hydroxyurea; In Vitro Techniques; Leukemia; Leukemia L1210; Leukemia, Lymphoid; Mechlorethamine; Mercaptopurine; Methotrexate; Mice; Mitosis; Nitroso Compounds; Prednisone; Thymidine; Time Factors; Tritium; Vinblastine; Vincristine | 1969 |
[Burkitt's lymphoma and acute leukemias].
Topics: Acute Disease; Animals; Asparaginase; Burkitt Lymphoma; Child; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Fluorouracil; Humans; Leukemia; Melphalan; Mercaptopurine; Methotrexate; Mice; Oncogenic Viruses; Prednisolone; Prednisone; Vincristine | 1969 |
Topical antimetabolites.
Topics: Antimetabolites; Antineoplastic Agents; Carcinoma, Basal Cell; Fluorouracil; Folic Acid Antagonists; Humans; Keratosis; Methotrexate; Mycosis Fungoides; Nitrogen Mustard Compounds; Ointments; Podophyllin; Precancerous Conditions; Skin Diseases; Skin Neoplasms; Virus Diseases | 1970 |
Cancer chemotherapy today and tomorrow. (A review).
Topics: Antineoplastic Agents; Child; Fluorouracil; Forecasting; Humans; Leukemia; Mercaptopurine; Methotrexate; Neoplasms; Prognosis | 1971 |
[Cytostatic chemotherapy of neoplasms in children].
Topics: Adrenal Cortex Hormones; Aminopterin; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Cytarabine; Daunorubicin; Fluorouracil; Humans; Leukemia; Lymphoma; Mercaptopurine; Methotrexate; Nitrogen Mustard Compounds; Procarbazine; Sarcoma; Vinblastine; Vincristine | 1971 |
[Antimetabolites].
Topics: Allopurinol; Animals; Antimetabolites; Azathioprine; Cell Division; Chemical Phenomena; Chemistry; Cytarabine; DNA, Neoplasm; Fluorouracil; Folic Acid Antagonists; Humans; Leukemia; Mercaptopurine; Methotrexate; Neoplasms; Pyrimidines; Thioguanine | 1971 |
Chemotherapy of breast cancer.
Topics: Adrenal Cortex Hormones; Alkaloids; Alkylating Agents; Androgens; Antimetabolites; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Cytosine; Estrogens; Fluorouracil; Hormones; Humans; Mercaptopurine; Methotrexate; Mitomycins; Neoplasm Recurrence, Local; Nitrogen Mustard Compounds; Thiotepa | 1968 |
[Current status of chemotherapy of malignant tumors of the ovaries].
Topics: Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Ovarian Neoplasms; Thiotepa; Triaziquone; Vinblastine | 1968 |
Chemotherapy strategies in squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Random Allocation; Sex Factors; Time Factors | 1984 |
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Mechlorethamine; Mercaptopurine; Methotrexate; Procarbazine; Vinblastine | 1980 |
Cytotoxic drugs and the granulopoietic system.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bone Marrow; Busulfan; Chlorambucil; Colony-Forming Units Assay; Cyclophosphamide; Cytarabine; Cytotoxins; Dactinomycin; Fluorouracil; Granulocytes; Hematopoietic Stem Cells; Hematopoietic System; Humans; Methotrexate; Nitrogen Mustard Compounds; Nitrosourea Compounds; Vinblastine | 1982 |
Changing role of chemotherapy in treatment of head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Recurrence | 1982 |
Effect of human renal and hepatic disease on the pharmacokinetics of anticancer drugs.
Topics: Antineoplastic Agents; Aspartic Acid; Bleomycin; Cisplatin; Cyclophosphamide; Doxorubicin; Fluorouracil; Gallium; Humans; Kidney Diseases; Kinetics; Liver Diseases; Metabolic Clearance Rate; Methotrexate; Phosphonoacetic Acid; Protein Binding; Tegafur | 1982 |
Introduction to chemotherapy and antineoplastic pharmacology in breast cancer.
Topics: Aminoglutethimide; Androgens; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Estrogen Antagonists; Estrogens; Female; Fluorouracil; Glucocorticoids; Humans; Male; Methotrexate; Palliative Care; Progestins; Receptors, Estrogen; Receptors, Progesterone | 1982 |
Thymidine as an anticancer agent, alone or in combination. A biochemical appraisal.
Topics: Animals; Antineoplastic Agents; Azacitidine; Cytarabine; Decitabine; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Neoplasms; Thymidine | 1982 |
Chemotherapy of esophageal cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Doxorubicin; Esophageal Neoplasms; Etoposide; Fluorouracil; Humans; Lomustine; Methotrexate; Mitoguazone; Mitomycin; Mitomycins; Neoplasm Metastasis; Postoperative Care; Preoperative Care; Vinblastine; Vindesine | 1984 |
Combined-modality therapy of esophageal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Doxorubicin; Esophageal Neoplasms; Esophagus; Fluorouracil; Humans; Methotrexate; Postoperative Care; Preoperative Care; Radiotherapy Dosage; Time Factors; Vinblastine; Vindesine | 1984 |
Systemic therapy of bladder cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Transitional Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Methotrexate; Mitomycin; Mitomycins; Urinary Bladder Neoplasms | 1984 |
Chemotherapy in alimentary tract malignomas.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carmustine; Colonic Neoplasms; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lomustine; Male; Methotrexate; Mitomycin; Mitomycins; Rectal Neoplasms; Semustine; Stomach Neoplasms; Streptozocin; Tegafur; Vincristine | 1981 |
Chemotherapy of hormonally unresponsive prostatic carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carmustine; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Diethylstilbestrol; Doxorubicin; Estramustine; Fluorouracil; Humans; Imidazoles; Lomustine; Male; Methotrexate; Mitomycin; Mitomycins; Prednimustine; Prednisone; Procarbazine; Prostatic Neoplasms; Random Allocation; Streptozocin; Vincristine | 1984 |
Chemotherapy of breast cancer: current views and results.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Prognosis; Receptors, Estrogen; Research Design | 1983 |
Chemotherapy of advanced transitional cell carcinoma of the uroepithelium.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Methotrexate; Urinary Bladder Neoplasms | 1983 |
Chemotherapy principles in the treatment of prostatic cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Castration; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Evaluation, Preclinical; Estradiol Congeners; Fluorouracil; Humans; Male; Methotrexate; Prostatic Neoplasms; Rats; Structure-Activity Relationship; Testosterone Congeners | 1984 |
Pharmacology of intraperitoneal chemotherapy.
Topics: Antineoplastic Agents; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Metabolic Clearance Rate; Methotrexate; Ovarian Neoplasms; Peritoneum | 1983 |
Immunosuppressant therapy.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antilymphocyte Serum; Arthritis, Rheumatoid; Azathioprine; Cyclophosphamide; Cyclosporins; Fluorouracil; Humans; Immunosuppressive Agents; Leukocytes; Methotrexate; Vinca Alkaloids | 1984 |
Dose-dependent metabolism, therapeutic effect, and toxicity of anticancer drugs in man.
Topics: Alanine; Antineoplastic Agents; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Fluorouracil; Humans; Ifosfamide; Kinetics; Methotrexate; Thymidine | 1983 |
[Adjuvant chemotherapy in breast cancer: status in 1984].
Topics: Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Neoplasm Recurrence, Local; Time Factors | 1984 |
The use of intraperitoneal chemotherapy in the treatment of ovarian cancer.
Topics: Antineoplastic Agents; Catheters, Indwelling; Cisplatin; Doxorubicin; Female; Fluorouracil; Humans; Injections, Intraperitoneal; Methotrexate; Ovarian Neoplasms; Peritoneal Dialysis | 1984 |
Neurological complications of antineoplastic therapy.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Aspartic Acid; Cisplatin; Cytarabine; Fluorouracil; Humans; Methotrexate; Nervous System Diseases; Phosphonoacetic Acid; Thymidine; Vinblastine; Vincristine | 1984 |
The role of post-operative radiotherapy in the treatment of operable breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Neoplasm Staging | 1984 |
The importance of dose intensity in chemotherapy of metastatic breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prednisone; Vincristine | 1984 |
Hormone receptors. An update and application.
Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Menopause; Methotrexate; Prednisone; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Vincristine | 1984 |
Adjuvant systemic therapy in primary breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Castration; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Fluorouracil; Humans; Mastectomy; Melphalan; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Random Allocation; Receptors, Estrogen; Tamoxifen; Time Factors | 1984 |
Cytotoxic agents effective in prostate cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Lomustine; Male; Methotrexate; Prostatic Neoplasms; Semustine | 1983 |
Chemotherapy of breast cancer.
Topics: Adrenalectomy; Alkylating Agents; Aminoglutethimide; Androgens; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Doxorubicin; Estrogens; Female; Fluorouracil; Humans; Immunotherapy; Methotrexate; Naphthacenes; Pituitary Hormone-Releasing Hormones; Progestins; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Vinca Alkaloids | 1984 |
The chemotherapy of bladder carcinoma: systemic therapy.
Topics: Alkylating Agents; Antineoplastic Agents; Cisplatin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Mitomycin; Mitomycins; Urinary Bladder Neoplasms; Vinca Alkaloids | 1983 |
Adjuvant chemotherapy for early breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasm Metastasis; Time Factors | 1983 |
[Pharmacokinetics of antitumor drugs].
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dichlorodiphenyldichloroethane; Dogs; Doxorubicin; Fluorouracil; Guanazole; Humans; Kinetics; Methotrexate; Mice; Models, Biological; Rats; Thiotepa | 1983 |
Chemotherapy of ovarian cancer.
Topics: Altretamine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Estrogen Antagonists; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Ovarian Neoplasms; Progestins; Tamoxifen | 1984 |
Selective uptake and retention of anticancer agents by sensitive cells.
Topics: Animals; Antineoplastic Agents; Cytarabine; Doxorubicin; Floxuridine; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasms | 1980 |
Drug-induced megaloblastic change.
Topics: Cyclophosphamide; Cytarabine; DNA; Erythrocytes, Abnormal; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Hydroxyurea; Megaloblasts; Methotrexate; Phenytoin; Pyrimethamine; Ribonucleotides; Thymidine Monophosphate; Thymidylate Synthase; Triamterene; Trimethoprim | 1980 |
[Sarcoma of the uterus].
Topics: Adolescent; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hysterectomy; Methotrexate; Sarcoma; Uterine Cervical Neoplasms; Uterine Neoplasms; Vincristine | 1982 |
Is there a role for thymidine in cancer chemotherapy?
Topics: Cytarabine; Drug Therapy, Combination; Fluorouracil; Humans; Kinetics; Leukemia; Methotrexate; Neoplasms; Thymidine | 1982 |
Endocrine and cytostatic treatment of experimental mammary cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carmustine; Castration; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Ergolines; Female; Fluorouracil; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; Mice; Nitrosourea Compounds; Prednisolone; Rats; Tamoxifen; Vincristine | 1980 |
The effect of chemotherapeutic agents on wound healing.
Topics: Adrenal Cortex Hormones; Anemia; Animals; Antineoplastic Agents; Azathioprine; Collagen; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Fluorouracil; Humans; Leukopenia; Mechlorethamine; Mercaptopurine; Methotrexate; Neoplasms; Tensile Strength; Thiotepa; Time Factors; Wound Healing | 1981 |
[Metabolic modulation as a method in tumor chemotherapy].
Topics: Antineoplastic Agents; Cytarabine; Fluorouracil; Humans; Methotrexate; Neoplasms; Tegafur; Thymidine; Uracil | 1982 |
An overview of thymidine.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Methylthioinosine; Mice; Neoplasms; Thymidine | 1980 |
Perspective on the design and biochemical pharmacology of inhibitors of thymidylate synthetase.
Topics: Antineoplastic Agents; Deoxyuracil Nucleotides; Deoxyuridine; Fluorodeoxyuridylate; Fluorouracil; Methotrexate; Methyltransferases; Protein Binding; Structure-Activity Relationship; Thymidylate Synthase; Uracil | 1980 |
[Cytostatic therapy: neurologic and psychiatric syndromes].
Topics: Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Dacarbazine; Dactinomycin; Doxorubicin; Fluorouracil; Humans; Methotrexate; Nervous System Diseases; Nitrosourea Compounds; Procarbazine; Psychoses, Substance-Induced; Vincristine | 1980 |
Advances in the multimodal primary management of cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Osteosarcoma | 1980 |
Recent progress in breast cancer management. Combined modality (adjuvant) therapy.
Topics: Adult; Animals; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Mammary Neoplasms, Experimental; Melphalan; Methotrexate; Middle Aged; Prednisone; Vincristine | 1981 |
[Adjuvant chemotherapy in breast cancer].
Topics: Antineoplastic Agents; Axilla; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Vincristine | 1981 |
The case for adjuvant CMF chemotherapy in breast cancer. Has it been made?
Topics: Axilla; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Menopause; Methotrexate | 1981 |
[The present state of the art in diagnosis and therapy of cancer of the breast (author's transl)].
Topics: Adult; Biopsy; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Node Excision; Mammography; Mastectomy; Methotrexate; Neoplasm Metastasis; Palpation; Prognosis; Radiation Protection; Risk; Tamoxifen; Thermography; Time Factors; Ultrasonography; Xeromammography | 1982 |
Preclinical and clinical aspects of biomodulation of 5-fluorouracil.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cisplatin; Colorectal Neoplasms; DNA, Neoplasm; Fluorouracil; Humans; Idoxuridine; Immunologic Factors; Interferons; Leucovorin; Methotrexate; Mice; Phosphonoacetic Acid; RNA, Neoplasm; Uracil; Uridine; Zidovudine | 1994 |
Fluorouracil modulation in head and neck cancer.
Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Immunologic Factors; Interferons; Leucovorin; Methotrexate | 1993 |
Adjuvant systemic therapy for breast cancer. Issues for primary care physicians.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Prognosis; Tamoxifen | 1995 |
Antimetabolites reduce the activities of enzymes with short half-lives in addition to inhibiting their specific targets.
Topics: Animals; Antimetabolites, Antineoplastic; Bone Marrow; Cycloheximide; Enzyme Inhibitors; Fluorouracil; Half-Life; Humans; Isoxazoles; Methotrexate; Prodrugs; Purines; Pyrimidines; Ribavirin; Signal Transduction | 1994 |
Cytotoxic chemotherapy for advanced hormone-resistant prostate cancer.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bone Neoplasms; Cisplatin; Clinical Trials as Topic; Coumarins; Doxorubicin; Drug Administration Schedule; Drug Resistance; Fluorouracil; Humans; Intercalating Agents; Male; Methotrexate; Neoplasm Staging; Polyamines; Prostate-Specific Antigen; Prostatic Neoplasms; Remission Induction; Somatostatin | 1993 |
Recurrent breast cancer: presentation, diagnosis, and treatment.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Bone Neoplasms; Breast Neoplasms; Central Nervous System Neoplasms; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Mastectomy; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Palliative Care; Radiotherapy; Soft Tissue Neoplasms | 1993 |
[Chemotherapy of metastasizing cancers of the colon and rectum].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic Neoplasms; Fluorouracil; Humans; Interferons; Leucovorin; Methotrexate; Neoplasm Metastasis; Phosphonoacetic Acid; Rectal Neoplasms | 1993 |
The pharmacologic modulation of 5-fluorouracil with folinic acid, methotrexate, trimetrexate, and n-phosphonacetyl-l-aspartic acid (PALA). Mechanisms of the interactions and clinical data.
Topics: Aspartic Acid; Drug Interactions; Fluorouracil; Humans; Leucovorin; Methotrexate; Neoplasms; Phosphonoacetic Acid; Trimetrexate | 1994 |
Antimetabolites.
Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; Drug Resistance; Fluorouracil; Humans; Mercaptopurine; Methotrexate; Vidarabine | 1994 |
The use of mitoxantrone in the treatment of breast cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Mitoxantrone; Prednisone; Quality of Life | 1995 |
[Recent advances in chemotherapy for advanced gastric cancer: from the standpoint of survival advantages].
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Doxorubicin; Fluorouracil; Humans; Methotrexate; Mitomycin; Prognosis; Randomized Controlled Trials as Topic; Stomach Neoplasms; Survival Rate | 1995 |
Non small cell lung cancer and chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Fluorouracil; Humans; Indazoles; Lomustine; Lung Neoplasms; Methotrexate; Neoplasm Staging; Treatment Outcome | 1994 |
The relationship between an objective response to chemotherapy and survival in advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Multivariate Analysis; Prognosis; Reproducibility of Results | 1994 |
Lobular carcinoma of the male breast.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Lobular; Combined Modality Therapy; Cyclophosphamide; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Tamoxifen | 1994 |
Chemotherapy for colorectal cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Methotrexate | 1994 |
Clinical pharmacokinetics of anti-metabolites.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cytarabine; Fluorouracil; Humans; Mercaptopurine; Methotrexate; Neoplasms | 1993 |
Neurotoxicity secondary to antineoplastic drugs.
Topics: Antineoplastic Agents; Central Nervous System; Cisplatin; Cytarabine; Female; Fluorouracil; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Nervous System; Vinca Alkaloids | 1994 |
Meta-analysis of randomized trials testing the biochemical modulation of fluorouracil by methotrexate in metastatic colorectal cancer. Advanced Colorectal Cancer Meta-Analysis Project.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Randomized Controlled Trials as Topic; Regression Analysis; Survival Analysis | 1994 |
Cellular interactions between the natural and unnatural isomers of 5-formyltetrahydrofolate.
Topics: Animals; Cell Division; Cell Survival; Fluorouracil; Folic Acid; Humans; Leucovorin; Methotrexate; Stereoisomerism; Tumor Cells, Cultured | 1993 |
[Adjuvant treatment of breast carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Multicenter Studies as Topic; Ovariectomy; Risk Factors; Tamoxifen | 1993 |
Kinetic concepts in the treatment of breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Cycle; Cell Division; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Kinetics; Methotrexate; Mutagenesis; Mutation | 1993 |
Double modulation of 5-fluorouracil in the treatment of advanced colorectal carcinoma: report of a trial with sequential methotrexate, intravenous (loading dose) folinic acid, 5-fluorouracil, and a literature review.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colorectal Neoplasms; Diarrhea; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome | 1994 |
Antimetabolites.
Topics: Antimetabolites, Antineoplastic; Cytarabine; Drug Design; Drug Resistance; Floxuridine; Fluorouracil; Humans; Methotrexate; Purines | 1993 |
Recent advances in the treatment of advanced colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colorectal Neoplasms; Drug Administration Schedule; Drug Interactions; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Hydroxyurea; Infusions, Intra-Arterial; Leucovorin; Methotrexate; Neoplasm Staging; Phosphonoacetic Acid; Prospective Studies; Randomized Controlled Trials as Topic | 1993 |
Chemotherapy and survival in advanced breast cancer: the inclusion of doxorubicin in Cooper type regimens.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Meta-Analysis as Topic; Methotrexate; Prednisone; Proportional Hazards Models; Vincristine | 1993 |
Cancer chemotherapy and biological response modifiers annual 16. Introduction.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Survival; Cytidine; DNA Damage; DNA Repair; Fluorouracil; Humans; Methotrexate; Purines | 1996 |
Antimetabolites.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Survival; Cytidine; DNA Damage; DNA Repair; Fluorouracil; Humans; Methotrexate; Purines | 1996 |
The treatment of advanced gastric cancer.
Topics: Antibiotics, Antineoplastic; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Etoposide; Fluorouracil; Gastrectomy; Humans; Leucovorin; Methotrexate; Mitomycins; Randomized Controlled Trials as Topic; Stomach Neoplasms | 1996 |
[Adjuvant chemotherapy for advanced gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cytarabine; Doxorubicin; Drug Administration Schedule; Fluorouracil; Humans; Methotrexate; Mitomycin; Stomach Neoplasms | 1996 |
Optimal control of cyclophosphamide-induced emesis.
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Epirubicin; Fluorouracil; Humans; Lomustine; Methotrexate; Procarbazine; Randomized Controlled Trials as Topic; Vomiting | 1996 |
[Chemotherapy of head and neck cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Remission Induction | 1996 |
Adjuvant drug therapy for operable breast cancer.
Topics: Age Distribution; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Hematopoietic Stem Cell Transplantation; Humans; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy, Adjuvant; Risk Assessment; Tamoxifen | 1996 |
Methotrexate: an effective agent for treating cancer and building careers. The polyglutamate era.
Topics: Animals; Antimetabolites, Antineoplastic; Fluorouracil; Humans; Leucovorin; Methotrexate; Mice; Neoplasms; Polyglutamic Acid | 1996 |
How to optimize the effect of 5-fluorouracil modulated therapy in advanced colorectal cancer.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Clinical Trials as Topic; Colorectal Neoplasms; Fluorouracil; Humans; Interferons; Leucovorin; Liver Neoplasms; Methotrexate; Phosphonoacetic Acid | 1995 |
Current treatment modalities in advanced colorectal carcinoma.
Topics: Colorectal Neoplasms; Fluorouracil; Humans; Interferons; Methotrexate; Prognosis; Quality of Life | 1996 |
Modulated 5-fluorouracil (5-FU) regimens in advanced colorectal cancer: a critical review of comparative studies.
Topics: Antimetabolites, Antineoplastic; Colorectal Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Interferon alpha-2; Interferon-alpha; Leucovorin; Methotrexate; Recombinant Proteins | 1996 |
[Significance of cytostatic drug dose in adjuvant chemotherapy of breast carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Survival Rate; Treatment Outcome | 1996 |
[CMF or CAF combination chemotherapy for breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Mitomycin | 1996 |
[Sequential methotrexate and 5-fluorouracil].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Drug Synergism; Fluorouracil; Humans; Methotrexate; Stomach Neoplasms | 1996 |
[A case of alpha-fetoprotein-producing pancreatic carcinoma--review of 41 cases reported in Japan].
Topics: Adenocarcinoma; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Humans; Immunohistochemistry; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Stents | 1996 |
Fluorouracil in colorectal cancer--a tale of two drugs: implications for biochemical modulation.
Topics: Antidotes; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Leucovorin; Methotrexate; Randomized Controlled Trials as Topic | 1997 |
Meningeal carcinomatosis as the presenting manifestation of gastric adenocarcinoma.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ring Cell; Doxorubicin; Fluorouracil; Humans; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Stomach Neoplasms | 1997 |
Resistance to chemotherapeutic antimetabolites: a function of salvage pathway involvement and cellular response to DNA damage.
Topics: Animals; Antimetabolites, Antineoplastic; Aspartic Acid; DNA Damage; Drug Resistance; Fluorouracil; Humans; Methotrexate; Phosphonoacetic Acid; Purines; Pyrimidines; Tumor Suppressor Protein p53 | 1997 |
Amenorrhea induced by adjuvant chemotherapy in early breast cancer patients: prognostic role and clinical implications.
Topics: Amenorrhea; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Fluoxymesterone; Humans; Melphalan; Methotrexate; Premenopause; Prognosis; Thiotepa; Vinblastine | 1997 |
Paclitaxel as first-line treatment for metastatic breast cancer. The Taxol Investigational Trials Group, Australia and New Zealand.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Neoplasm Metastasis; Paclitaxel; Quality of Life | 1997 |
[Acquisition of resistance to anticancer agents by overproduction of target enzymes].
Topics: Animals; Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Enzymes; Fluorouracil; Gene Amplification; Genetic Code; Humans; Methotrexate; Neoplasms | 1997 |
Arterial infusion chemotherapy for peritoneal and liver metastasis in gastric cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Lymphatic Metastasis; Methotrexate; Neoplasm Recurrence, Local; Peritoneal Neoplasms; Stomach Neoplasms | 1997 |
The dead end of 5-fluorouracil double modulation and promise of continuous infusion schedules in the treatment of metastatic colorectal cancer.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Clinical Trials, Phase II as Topic; Colorectal Neoplasms; Combined Modality Therapy; Dipyridamole; Drug Administration Schedule; Drug Synergism; Enzyme Inhibitors; Female; Fluorouracil; Humans; Immunologic Factors; Infusions, Intravenous; Injections, Intravenous; Interferons; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Neoplasm Proteins; Nucleotides; Palliative Care; Phosphonoacetic Acid; Randomized Controlled Trials as Topic; Thymidylate Synthase | 1996 |
[Benefits of adjuvant chemotherapy for breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Drug Combinations; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Mitomycin; Randomized Controlled Trials as Topic; Tamoxifen; Tegafur; Uracil | 1997 |
Biomodulation of 5-fluorouracil with antifolates.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Fluorouracil; Folic Acid Antagonists; Humans; Leucovorin; Methotrexate; Trimetrexate | 1997 |
How should we introduce high-dose chemotherapeutic strategies into the adjuvant management of high-risk breast cancer in Australasia?
Topics: Antineoplastic Combined Chemotherapy Protocols; Australia; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Hematopoietic Stem Cell Transplantation; Humans; Methotrexate; Risk Management | 1998 |
Adjuvant systemic therapy for women with node-negative breast cancer. The Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer.
Topics: Adult; Age Factors; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Professional Staff Committees; Prognosis; Tamoxifen | 1998 |
Adjuvant systemic therapy for women with node-positive breast cancer. The Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer.
Topics: Adult; Age Factors; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Professional Staff Committees; Tamoxifen; Time Factors | 1998 |
[Treatment for recurrent head and neck carcinomas].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Carcinoma, Squamous Cell; Cell Division; Cisplatin; Combined Modality Therapy; Epirubicin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy Dosage | 1998 |
[Treatment of recurrent gastric cancer].
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Doxorubicin; Drug Administration Schedule; Epirubicin; Etoposide; Fluorouracil; Humans; Immunologic Factors; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Methotrexate; Mitomycin; Neoplastic Cells, Circulating; Peritoneal Neoplasms; Stomach Neoplasms | 1998 |
[Chemotherapy of gastric cancer].
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Etoposide; Fluorouracil; Humans; Immunologic Factors; Irinotecan; Methotrexate; Stomach Neoplasms | 1998 |
Antimetabolites.
Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; DNA; Drug Resistance, Neoplasm; Fluorouracil; Folic Acid; Humans; Methotrexate | 1997 |
Adjuvant chemoendocrine therapy in postmenopausal breast cancer: cyclophosphamide, methotrexate, and fluorouracil dose and schedule may make a difference. International Breast Cancer Study Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Postmenopause; Tamoxifen | 1998 |
Tumor resistance to antimetabolites.
Topics: Antimetabolites, Antineoplastic; Cell Cycle Proteins; Deoxycytidine; DNA Damage; DNA, Neoplasm; Drug Resistance, Neoplasm; Fluorouracil; Gemcitabine; Gene Amplification; Humans; Methotrexate; Mutation; Neoplasms; Quinazolines; Thiophenes | 1998 |
Biomodulation of Fluorouracil in colorectal cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Clinical Trials as Topic; Colorectal Neoplasms; Drug Synergism; Fluorouracil; Humans; Interferon-alpha; Leucovorin; Methotrexate; Phosphonoacetic Acid; Trimetrexate | 1998 |
Cooperative antitumor effect of mixed backbone oligonucleotides targeting protein kinase A in combination with cytotoxic drugs or biologic agents.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Camptothecin; Cell Division; Cisplatin; Colonic Neoplasms; Combined Modality Therapy; Cyclic AMP-Dependent Protein Kinases; Doxorubicin; Drug Design; Drug Screening Assays, Antitumor; Drug Synergism; ErbB Receptors; Female; Fluorouracil; Genetic Therapy; Humans; Methotrexate; Oligonucleotides, Antisense; Ovarian Neoplasms; Paclitaxel; Structure-Activity Relationship; Thionucleotides; Tumor Cells, Cultured; Vincristine | 1998 |
[No advantage to using the CMF-regimen for node positive, postmenopausal, receptor-positive mammary carcinoma with adjuvant tamoxifen therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Postmenopause; Prognosis; Randomized Controlled Trials as Topic; Tamoxifen | 1998 |
Adding adjuvant CMF chemotherapy to either radiotherapy or tamoxifen: are all CMFs alike? The International Breast Cancer Study Group (IBCSG).
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Tamoxifen | 1998 |
Postmastectomy radiation therapy: better late than never.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Humans; Lymph Node Excision; Mastectomy; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Treatment Outcome | 1998 |
Medical management of advanced gastric cancer.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Fluorouracil; Humans; Methotrexate; Mitomycin; Randomized Controlled Trials as Topic; Stomach Neoplasms; Survival Rate | 1998 |
[Improving the anti-tumor activity of 5-fluorouracil by methotrexate].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; DNA; Drug Administration Schedule; Drug Synergism; Fluorouracil; Humans; Methotrexate; Stomach Neoplasms | 1999 |
Therapeutic drug monitoring of antimetabolic cytotoxic drugs.
Topics: Antimetabolites, Antineoplastic; Cytarabine; Drug Monitoring; Fluorouracil; Humans; Mercaptopurine; Methotrexate; Neoplasms | 1999 |
Role of red blood cells in pharmacokinetics of chemotherapeutic agents.
Topics: Administration, Oral; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Doxorubicin; Epirubicin; Erythrocytes; Fluorouracil; Humans; Ifosfamide; Infusions, Parenteral; Mercaptopurine; Methotrexate; Paclitaxel; Platinum Compounds | 1999 |
[A case of liver metastases of rectal carcinoid successfully treated with hepatic arterial infusion of methotrexate and 5-fluorouracil].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Methotrexate; Pelvic Exenteration; Rectal Neoplasms | 1999 |
Where do we stand with 5-fluorouracil?
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Chronotherapy; Colorectal Neoplasms; Dipyridamole; Drug Synergism; Fluorouracil; Humans; Interferons; Leucovorin; Levamisole; Methotrexate; Phosphonoacetic Acid; Radiation-Sensitizing Agents; Trimetrexate; Zidovudine | 1999 |
Survival impact of chemotherapy in patients with colorectal metastases confined to the liver: a re-analysis of 1458 non-operable patients randomised in 22 trials and 4 meta-analyses. Meta-Analysis Group in Cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Evaluation Studies as Topic; Female; Floxuridine; Fluorouracil; Humans; Injections, Intralesional; Liver Neoplasms; Male; Methotrexate; Middle Aged; Palliative Care; Prognosis; Randomized Controlled Trials as Topic; Survival Analysis; Terminally Ill; Treatment Outcome | 1999 |
Early start of adjuvant chemotherapy may improve treatment outcome for premenopausal breast cancer patients with tumors not expressing estrogen receptors. The International Breast Cancer Study Group.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Premenopause; Proportional Hazards Models; Randomized Controlled Trials as Topic; Receptors, Estrogen; Treatment Outcome | 2000 |
Oral alkylating agents for breast cancer therapy.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Humans; Methotrexate | 1999 |
Adjuvant cyclophosphamide, methotrexate, fluorouracil (CMF) in breast cancer--is it cost-effective?
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cost-Benefit Analysis; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Norway; Prognosis; Quality-Adjusted Life Years | 2000 |
Chemotherapy dose reduction and delay in clinical practice. evaluating the risk to patient outcome in adjuvant chemotherapy for breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Randomized Controlled Trials as Topic; Risk Factors | 2000 |
Antimetabolites.
Topics: Animals; Antimetabolites, Antineoplastic; Cladribine; Cytarabine; Deoxycytidine; Drug Resistance, Neoplasm; Fluorouracil; Gemcitabine; Humans; Methotrexate | 1999 |
[Effects of chemotherapy on the changes of histology and function of the ovary].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Daunorubicin; Female; Fluorouracil; Humans; Methotrexate; Ovary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine | 1998 |
Bilateral recurrent pneumothorax complicating chemotherapy for pulmonary metastatic breast ductal carcinoma: report of a case.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Cyclophosphamide; Drainage; Female; Fluorouracil; Follow-Up Studies; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Mitomycin; Mitoxantrone; Pneumothorax; Recurrence; Treatment Outcome | 2000 |
Is chemotherapy alone adequate for young women with oestrogen-receptor-positive breast cancer?
Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Multicenter Studies as Topic; Ovariectomy; Prednisone; Premenopause; Prognosis; Randomized Controlled Trials as Topic; Receptors, Estrogen; Risk Factors | 2000 |
Preoperative therapy for local-regional gastric cancer: rationale and review of trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Doxorubicin; Etoposide; Fluorouracil; Humans; Methotrexate; Mitomycin; Preoperative Care; Stomach Neoplasms; Tegafur; Uracil | 2000 |
Chemotherapy of metastatic gastric cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Epirubicin; Etoposide; Fluorouracil; Humans; Leucovorin; Methotrexate; Randomized Controlled Trials as Topic; Stomach Neoplasms | 2000 |
Relation between tumour response to first-line chemotherapy and survival in advanced colorectal cancer: a meta-analysis. Meta-Analysis Group in Cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Floxuridine; Fluorouracil; Leucovorin; Methotrexate; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome | 2000 |
HER2. a 'predictive factor' ready to use in the daily management of breast cancer patients?
Topics: Anthracyclines; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Methotrexate; Predictive Value of Tests; Receptor, ErbB-2; Tamoxifen | 2000 |
Management of nail psoriasis.
Topics: Administration, Topical; Anti-Inflammatory Agents; Antifungal Agents; Cyclosporine; Dermatologic Agents; Female; Fluorouracil; Glucocorticoids; Humans; Keratosis; Male; Methotrexate; Nail Diseases; Psoriasis; Triamcinolone Acetonide | 2000 |
[Standard chemotherapy for metastatic breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Docetaxel; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Paclitaxel; Practice Guidelines as Topic; Prognosis; Taxoids | 2000 |
Survival in patients with intermediate or high grade non-Hodgkin's lymphoma: meta-analysis of randomized studies comparing third generation regimens with CHOP.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Doxorubicin; Fluorouracil; Humans; Leucovorin; Lymphoma, Non-Hodgkin; Methotrexate; Prednisone; Randomized Controlled Trials as Topic; Survival Analysis; Vincristine | 2001 |
Biochemical modulation of 5-FU in systemic treatment of advanced colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Synergism; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Injections, Intravenous; Leucovorin; Meta-Analysis as Topic; Methotrexate; Randomized Controlled Trials as Topic | 2001 |
Randomized trials of high dose chemotherapy for breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Clinical Trials, Phase II as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Randomized Controlled Trials as Topic; Survival Analysis; Thiotepa | 2001 |
[MTX/5FU sequential therapy for advanced and recurrent gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Disseminated Intravascular Coagulation; Female; Fluorouracil; Folic Acid Antagonists; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Quality of Life; Ribonucleotide Reductases; Stomach Neoplasms; Thymidylate Synthase; Treatment Outcome | 2001 |
Treatment of metastatic pancreatic adenocarcinoma: a comprehensive review.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Deoxycytidine; Fluorouracil; Gemcitabine; Humans; Irinotecan; Methotrexate; Pancreatic Neoplasms; Randomized Controlled Trials as Topic | 2001 |
[Adjuvant therapy of breast cancer].
Topics: Adult; Age Factors; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Goserelin; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Ovariectomy; Postoperative Care; Preoperative Care; Prognosis; Risk Factors; Tamoxifen | 2001 |
Therapeutic drug monitoring of cytotoxic drugs.
Topics: Antimetabolites, Antineoplastic; Drug Interactions; Drug Monitoring; Fluorouracil; Humans; Mercaptopurine; Methotrexate; Neoplasms | 2001 |
Adjuvant treatment in node-negative, postmenopausal breast cancer.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Patient Care Planning; Postmenopause; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Risk Factors; Tamoxifen | 2001 |
What is the ideal duration of adjuvant therapy for primary breast cancer: are four cycles of cyclophosphamide and doxorubicin enough?
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Prognosis | 2001 |
Dose scheduling--Herceptin.
Topics: Abdominal Muscles; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Capecitabine; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Deoxycytidine; Drug Administration Schedule; Drug Antagonism; Drug Evaluation, Preclinical; Drug Synergism; Feasibility Studies; Female; Fluorouracil; Half-Life; Haplorhini; Humans; Infusions, Intravenous; Injections, Subcutaneous; Methotrexate; Neoplasm Metastasis; Paclitaxel; Safety; Trastuzumab; Treatment Outcome; Vinblastine; Xenograft Model Antitumor Assays | 2001 |
New combinations with Herceptin in metastatic breast cancer.
Topics: Anastrozole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclophosphamide; Deoxycytidine; Doxorubicin; Drug Interactions; Drug Synergism; Epirubicin; Female; Fluorouracil; Gemcitabine; Heart Diseases; Hematologic Diseases; Humans; Methotrexate; Neoplasm Metastasis; Nitriles; Organoplatinum Compounds; Paclitaxel; Tamoxifen; Thiotepa; Trastuzumab; Treatment Outcome; Triazoles; Vinblastine; Vinorelbine | 2001 |
Anticipating the future role of radiotherapy and chemotherapy in the treatment of head and neck cancer: a lesson from Manchester.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Bleomycin; Chemotherapy, Adjuvant; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Forecasting; Head and Neck Neoplasms; Humans; Methotrexate; Time Factors; Treatment Outcome | 2001 |
The worldwide perspective in the adjuvant treatment of primary lymph node positive breast cancer.
Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Treatment Outcome; World Health Organization | 2001 |
Chemotherapy versus hormonal adjuvant treatment in premenopausal patients with breast cancer.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cohort Studies; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms; Premenopause; Risk Factors | 2002 |
Lacrimal duct stenosis and other ocular toxicity associated with adjuvant cyclophosphamide, methotrexate and 5-fluorouracil combination chemotherapy for early stage breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lacrimal Duct Obstruction; Methotrexate; Middle Aged; Neoplasm Staging; Postmenopause; Retrospective Studies | 2001 |
Meta-analysis of adjuvant cyclophosphamide/methotrexate/5-fluorouracil chemotherapy in postmenopausal women with estrogen receptor-positive, node-positive breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Survival Rate | 2001 |
Optimum anthracycline-based chemotherapy for early breast cancer.
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Staging | 2001 |
Rationale and use of epirubicin-based therapy in the adjuvant setting.
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Neoplasms, Second Primary; Prognosis; Risk Factors | 2000 |
Occult breast cancer and axillary mass.
Topics: Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cisplatin; Decision Trees; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Neoplasms, Unknown Primary; Practice Guidelines as Topic | 2001 |
Operable breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Practice Guidelines as Topic; Survival Analysis; Tamoxifen | 2001 |
Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Cell Cycle Proteins; Dihydrouracil Dehydrogenase (NADP); DNA-Binding Proteins; Drug Resistance, Neoplasm; E2F Transcription Factors; E2F1 Transcription Factor; Enzyme Inhibitors; Fluorouracil; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms; Nucleoside-Phosphate Kinase; Oxidoreductases; Tetrahydrofolate Dehydrogenase; Thymidine Phosphorylase; Thymidylate Synthase; Transcription Factors | 2002 |
Therapeutic advances in the management of metastatic colorectal cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Camptothecin; Clinical Trials as Topic; Colorectal Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Methotrexate; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin | 2001 |
Chemotherapy for breast cancer brain metastases.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Etoposide; Female; Fluorouracil; Humans; Methotrexate; Survival Rate; Treatment Outcome | 2002 |
[Recent advance in adjuvant therapy for breast cancer].
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Neoplasm Recurrence, Local; Prognosis; Survival Rate; Tamoxifen; Tegafur; Uracil | 2002 |
[Evolution of adjuvant chemotherapy of breast cancer from Bonadonna to the taxanes].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Paclitaxel; Postmenopause; Premenopause; Survival Analysis; Treatment Outcome | 2002 |
Contribution of meta-analyses to the evaluation of treatments for advanced colorectal cancer.
Topics: Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Colorectal Neoplasms; Data Interpretation, Statistical; Fluorouracil; Humans; Infusions, Intravenous; Interferon Type I; Leucovorin; Meta-Analysis as Topic; Methotrexate; Odds Ratio; Recombinant Proteins | 2002 |
Ten-year outcome after combined modality therapy for inflammatory breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Life Tables; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pennsylvania; Radiotherapy, Adjuvant; Remission Induction; Retrospective Studies; Survival Analysis; Treatment Outcome | 2003 |
21. The adjuvant treatment of breast cancer.
Topics: Acute Disease; Adult; Age Factors; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Chronic Disease; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Tamoxifen | 2003 |
[Cerebral ischemic events and anti-cancer therapy].
Topics: Adolescent; Adult; Antineoplastic Agents; Asparaginase; Brain Ischemia; Cerebral Hemorrhage; Child; Child, Preschool; Cisplatin; Disease Susceptibility; Female; Fluorouracil; Growth Inhibitors; Humans; Male; Methotrexate; Middle Aged; Neoplasms | 2003 |
Doxorubicin in combination with fluorouracil and cyclophosphamide (i.v. FAC regimen, day 1, 21) versus methotrexate in combination with fluorouracil and cyclophosphamide (i.v. CMF regimen, day 1, 21) as adjuvant chemotherapy for operable breast cancer: a
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Humans; Infusions, Intravenous; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Prospective Studies; Survival Rate; Treatment Outcome | 2003 |
[Erb-2 overexpression in breast cancer].
Topics: Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Prognosis; Receptor, ErbB-2; Risk Factors; Trastuzumab; Up-Regulation | 2003 |
Landmark adjuvant randomized clinical trials of systemic therapy in early breast cancer.
Topics: Anthracyclines; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Enzyme Inhibitors; Female; Fluorouracil; Humans; Methotrexate; Randomized Controlled Trials as Topic; Tamoxifen; Taxoids | 2003 |
BIOCHEMISTRY OF CANCER (METABOLIC ASPECTS).
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Azaguanine; Azaserine; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Floxuridine; Fluorouracil; Folic Acid; Glutamine; Leukemia L1210; Mercaptopurine; Methotrexate; Mitomycin; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Puromycin; Pyrimidines; Research; RNA; RNA, Neoplasm; Thioguanine; Thiouracil | 1963 |
NEWER ANTICANCER AGENTS.
Topics: Alkylating Agents; Antineoplastic Agents; Arsenicals; Cyclophosphamide; Dactinomycin; Fluorouracil; Humans; Mechlorethamine; Melphalan; Methotrexate; Mitomycin; Mitomycins; Neoplasms; Pharmacology; Steroids; Triethylenemelamine; Vinblastine; Vincristine | 1964 |
[CHEMOTHERAPY OF UTERINE CERVIX CARCINOMA].
Topics: Antineoplastic Agents; Azaguanine; Aziridines; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Fluorouracil; Humans; Infusions, Parenteral; Melphalan; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Triaziquone; Uracil Mustard; Uterine Cervical Neoplasms; Vinblastine | 1964 |
THERAPY OF THE MALIGNANT CARCINOID SYNDROME.
Topics: Anti-Allergic Agents; Antihypertensive Agents; Cyclophosphamide; Fluorouracil; Histamine H1 Antagonists; Humans; Malignant Carcinoid Syndrome; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Selective Serotonin Reuptake Inhibitors; Serotonin; Steroids; Surgical Procedures, Operative | 1965 |
Adjuvant chemotherapy in early breast cancer: optimal and suboptimal anthracycline-containing regimens.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Randomized Controlled Trials as Topic; Reproducibility of Results; Survival Analysis; Treatment Outcome | 2003 |
Ovarian ablation as adjuvant therapy for premenopausal women with breast cancer--another step forward.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Goserelin; Humans; International Cooperation; Methotrexate; Multicenter Studies as Topic; Ovary; Premenopause | 2003 |
[Adjuvant chemotherapy for breast cancer--a current controversy].
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Mastectomy, Segmental; Meta-Analysis as Topic; Methotrexate; Receptors, Estrogen; Survival Rate; Tamoxifen; Taxoids | 2004 |
Recent translational research: antiangiogenic therapy for breast cancer - where do we stand?
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Capecitabine; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Immunotherapy; Methotrexate; Neovascularization, Pathologic; Treatment Outcome | 2004 |
[Radiation and concomitant chemotherapy after surgery for breast cancer].
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pilot Projects; Postoperative Care; Radiotherapy Dosage; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Time Factors | 2004 |
[Sequencing of adjuvant treatment after surgery for invasive breast cancer].
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Hormones; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Postoperative Care; Prognosis; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Tamoxifen; Time Factors; Trastuzumab | 2004 |
Clinical outcome in patients with locally advanced bladder carcinoma treated with conservative multimodality therapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cystectomy; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Life Tables; Male; Methotrexate; Middle Aged; Muscle, Smooth; Neoadjuvant Therapy; Neoplasm Invasiveness; Radiotherapy, Adjuvant; Retrospective Studies; Salvage Therapy; Survival Analysis; Treatment Outcome; Urinary Bladder Neoplasms; Vinblastine | 2004 |
Invasive ductal carcinoma within a fibroadenoma of the breast.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Fine-Needle; Breast Neoplasms; Carcinoma, Ductal, Breast; Combined Modality Therapy; Cyclophosphamide; Female; Fibroadenoma; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Treatment Outcome | 2004 |
Anthracycline vs nonanthracycline adjuvant therapy for breast cancer.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Chemotherapy, Adjuvant; Clinical Trials as Topic; Cyclophosphamide; Deoxycytidine; Drug Administration Schedule; Drug Resistance, Neoplasm; Epirubicin; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Paclitaxel | 2004 |
30 years' follow up of randomised studies of adjuvant CMF in operable breast cancer: cohort study.
Topics: Adult; Aged; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Infusions, Intravenous; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Randomized Controlled Trials as Topic; Risk Factors; Survival Analysis; Treatment Outcome | 2005 |
Uridine diphosphoglucuronosyl transferase and methylenetetrahydrofolate reductase polymorphisms as genomic predictors of toxicity and response to irinotecan-, antifolate- and fluoropyrimidine-based chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Fluorouracil; Glucuronosyltransferase; Humans; Irinotecan; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Pharmacogenetics; Polymorphism, Genetic; Sensitivity and Specificity; Toxicogenetics | 2004 |
Available options in chemotherapy for advanced gastric cancer: the current developments in Japan.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Doxorubicin; Fluorouracil; Japan; Methotrexate; Stomach Neoplasms | 2005 |
Adjuvant anthracycline-based chemotherapy for early breast cancer: do the dose and schedule matter?
Topics: Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Treatment Outcome | 2005 |
Pharmacogenetics of folate-related drug targets in cancer treatment.
Topics: Animals; Antineoplastic Agents; Fluorouracil; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Models, Biological; Neoplasms; Pharmacogenetics; Polymorphism, Genetic; Thymidylate Synthase | 2005 |
Adjuvant fluorouracil, epirubicin and cyclophosphamide in early breast cancer: is it cost-effective?
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Cyclophosphamide; Drug Costs; Epirubicin; Female; Fluorouracil; Humans; Medical Records; Methotrexate; Norway; Survival Rate | 2005 |
Selection of adjuvant chemotherapy for treatment of node-positive breast cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Randomized Controlled Trials as Topic; Taxoids | 2005 |
Potential mechanisms for chemotherapy-induced impairments in cognitive function.
Topics: Anemia; Animals; Antineoplastic Agents; Attention; Blood-Brain Barrier; Cognition Disorders; Cyclophosphamide; Doxorubicin; Encephalitis; Fluorouracil; Humans; Inflammation; Language; Learning; Memory; Menopause; Methotrexate; Neoplasms; Oncology Nursing; Paclitaxel; Psychomotor Performance; Spatial Behavior | 2005 |
[SNPs associated with adverse effects].
Topics: Antineoplastic Agents; Camptothecin; Fluorouracil; Glucuronosyltransferase; Humans; Irinotecan; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Pharmacogenetics; Polymorphism, Genetic; Polymorphism, Single Nucleotide | 2005 |
Randomized phase III trials of adjuvant FAMTX or FEMTX compared with surgery alone in resected gastric cancer. A combined analysis of the EORTC GI Group and the ICCG.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Disease-Free Survival; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Randomized Controlled Trials as Topic; Stomach Neoplasms; Survival Analysis | 2006 |
[Thermo-chemo-radiotherapy for advanced biliary carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Gallbladder Neoplasms; Humans; Hyperthermia, Induced; Methotrexate; Neoplasm Staging; Quality of Life; Radiotherapy, Conformal; Treatment Outcome | 2006 |
[Adjuvant chemotherapy based on evidence-based medicine for breast cancer patients].
Topics: Anthracyclines; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Epirubicin; Evidence-Based Medicine; Female; Fluorouracil; Guidelines as Topic; Humans; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Meta-Analysis as Topic; Methotrexate; Receptor, ErbB-2; Taxoids; Trastuzumab | 2006 |
Chemotherapy options for patients with metastatic or recurrent squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Patient Selection; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Taxoids; Treatment Outcome | 2006 |
[Chemotherapy in advanced gastric cancer--to ensure timely and appropriate switch to subsequent treatment options].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Clinical Trials, Phase III as Topic; Docetaxel; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Methotrexate; Oxonic Acid; Paclitaxel; Stomach Neoplasms; Survival Rate; Taxoids; Tegafur | 2007 |
[Drug-induced leukoencephalopathy].
Topics: Antineoplastic Agents; Brain Edema; Cisplatin; Cytarabine; Fluorouracil; Humans; Hypertensive Encephalopathy; Immunosuppressive Agents; Methotrexate; Nervous System Diseases; Syndrome | 2007 |
Controversies of adjuvant endocrine treatment for breast cancer and recommendations of the 2007 St Gallen conference.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Goserelin; Humans; Methotrexate; Ovariectomy; Selective Estrogen Receptor Modulators; Tamoxifen | 2007 |
[Clinical research advancement on male breast cancer].
Topics: Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; BRCA2 Protein; Breast Neoplasms, Male; Carcinoma, Ductal, Breast; Carcinoma, Papillary; Chemotherapy, Adjuvant; Cisplatin; Fluorouracil; Humans; Male; Mastectomy; Methotrexate; Neoplasm Staging; Tamoxifen | 2007 |
[Drug-induced leukoencephalopathy].
Topics: Antineoplastic Agents; Antiviral Agents; Fluorouracil; Humans; Immunosuppressive Agents; Interferon-alpha; Methotrexate; Posterior Leukoencephalopathy Syndrome; Time Factors | 2007 |
Case report: Second primary small cell carcinoma of the trachea in a breast cancer survivor: a case report and literature review.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy, Modified Radical; Methotrexate; Neoplasms, Second Primary; Positron-Emission Tomography; Radiotherapy, Adjuvant; Tomography, X-Ray Computed; Tracheal Neoplasms; Treatment Outcome | 2008 |
Recurrent head and neck cancer: current treatment and future prospects.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Forecasting; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Palliative Care; Salvage Therapy | 2008 |
C677T and A1298C MTHFR polymorphisms, a challenge for antifolate and fluoropyrimidine-based therapy personalisation.
Topics: Animals; Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Fluorouracil; Folic Acid Antagonists; Humans; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Pharmacogenetics; Polymorphism, Genetic; Quinazolines; Thiophenes; Treatment Outcome | 2009 |
Ovarian suppression/ablation in premenopausal ER-positive breast cancer patients. Issues and recommendations.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Gonadotropin-Releasing Hormone; Goserelin; Humans; Menopause, Premature; Methotrexate; Middle Aged; Ovariectomy; Ovary; Premenopause; Quality of Life; Receptors, Estrogen; Tamoxifen | 2009 |
Role of the MTHFR polymorphisms in cancer risk modification and treatment.
Topics: Antineoplastic Agents; Drug Resistance, Neoplasm; Fluorouracil; Folic Acid; Genetic Predisposition to Disease; Humans; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Polymorphism, Single Nucleotide; Risk Factors | 2009 |
Adjuvant chemotherapy for older adults with breast cancer: making the standard a standard.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Chemotherapy, Adjuvant; Confidence Intervals; Deoxycytidine; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Proportional Hazards Models; Risk Assessment; Risk Factors | 2009 |
[Progress in chemotherapy for advanced gastric cancer].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cisplatin; Clinical Trials, Phase III as Topic; Deoxycytidine; Docetaxel; Doxorubicin; Drug Combinations; Fluorouracil; Gefitinib; Humans; Irinotecan; Methotrexate; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Paclitaxel; Quinazolines; Stomach Neoplasms; Survival Rate; Taxoids; Tegafur; Trastuzumab | 2009 |
Bevacizumab in metastatic breast cancer: a meta-analysis of randomized controlled trials.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Capecitabine; Cyclophosphamide; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Randomized Controlled Trials as Topic; Survival Analysis; Taxoids; Treatment Outcome | 2010 |
Therapeutic usefulness of postoperative adjuvant chemotherapy with Tegafur-Uracil (UFT) in patients with breast cancer: focus on the results of clinical studies in Japan.
Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Deoxycytidine; Drug Combinations; Female; Floxuridine; Fluorouracil; Humans; Japan; Methotrexate; Oxonic Acid; Tegafur; Uracil | 2010 |
Intralesional agents in the management of cutaneous malignancy: a review.
Topics: Aminolevulinic Acid; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Fluorouracil; Humans; Injections, Intralesional; Interferon-alpha; Interleukin-2; Lymphoma, B-Cell; Melanoma; Methotrexate; Neoplasm Metastasis; Rituximab; Skin Neoplasms | 2011 |
Intralesional chemotherapy for nonmelanoma skin cancer: a practical review.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Injections, Intralesional; Interferons; Male; Methotrexate; Practice Guidelines as Topic; Risk Assessment; Skin Neoplasms; Treatment Outcome | 2010 |
Chemotherapy for thymic tumors: induction, consolidation, palliation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Deoxycytidine; Doxorubicin; Fluorouracil; Gemcitabine; Humans; Methotrexate; Neoadjuvant Therapy; Palliative Care; Procarbazine; Thymoma; Thymus Neoplasms; Vincristine | 2011 |
[Molecular subtypes and individualized treatment of breast cancer].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Cetuximab; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Staging; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Trastuzumab | 2010 |
Neoadjuvant chemotherapy and concomitant trastuzumab in breast cancer: a pooled analysis of two randomized trials.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoadjuvant Therapy; Paclitaxel; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Trastuzumab | 2011 |
CMF revisited in the 21st century.
Topics: Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Taxoids | 2012 |
Management of recurrent head and neck cancer: recent progress and future directions.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Randomized Controlled Trials as Topic; Squamous Cell Carcinoma of Head and Neck; Taxoids; Treatment Outcome | 2011 |
Adjuvant treatments for triple-negative breast cancers.
Topics: Angiogenesis Inhibitors; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Capecitabine; Chemotherapy, Adjuvant; Cisplatin; Deoxycytidine; Female; Fluorouracil; Humans; Methotrexate; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Taxoids; Treatment Outcome | 2012 |
[Impact of taxanes in the adjuvant setting of node-negative breast cancers].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Cyclophosphamide; Disease-Free Survival; Docetaxel; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Lymph Nodes; Methotrexate; Paclitaxel; Tamoxifen; Taxoids | 2013 |
Effects of two chemotherapy regimens, anthracycline-based and CMF, on breast cancer disease free survival in the Eastern Mediterranean Region and Asia: a meta-analysis approach for survival curves.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Asia; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Mediterranean Region; Methotrexate; Prognosis; Survival Rate | 2013 |
Topical and intralesional treatment of nonmelanoma skin cancer: efficacy and cost comparisons.
Topics: Administration, Cutaneous; Aminoquinolines; Antineoplastic Agents; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Fluorouracil; Humans; Imiquimod; Injections, Intralesional; Interferon alpha-2; Interferon-alpha; Keratoacanthoma; Methotrexate; Recombinant Proteins; Skin Neoplasms | 2013 |
Current approaches for TYMS polymorphisms and their importance in molecular epidemiology and pharmacogenetics.
Topics: Antimetabolites, Antineoplastic; Fluorouracil; Humans; Methotrexate; Molecular Epidemiology; Pharmacogenetics; Polymorphism, Genetic; Thymidylate Synthase | 2013 |
[Chemotherapy in male external genital organs (testicular and penile cancer)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Chemotherapy, Adjuvant; Cisplatin; Cryopreservation; Etoposide; Fluorouracil; Humans; Ifosfamide; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasms, Germ Cell and Embryonal; Orchiectomy; Paclitaxel; Penile Neoplasms; Spermatozoa; Testicular Neoplasms; Vinblastine | 2013 |
Central nervous system toxicities of chemotherapeutic agents.
Topics: Antineoplastic Agents; Central Nervous System Diseases; Cisplatin; Cytarabine; Fluorouracil; Humans; Ifosfamide; Methotrexate; Neurotoxicity Syndromes; Posterior Leukoencephalopathy Syndrome; Vidarabine; Vincristine | 2014 |
[Should knowledge of BRCA1 status impact the choice of chemotherapy in metastatic breast cancer: a review].
Topics: Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Female; Fluorouracil; Genes, BRCA1; Humans; Methotrexate; Mutation; Phthalazines; Piperazines; Prospective Studies; Retrospective Studies; Taxoids | 2015 |
Predicting Anthracycline Benefit: TOP2A and CEP17-Not Only but Also.
Topics: Anthracyclines; Antigens, Neoplasm; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Centromere; Chromosomes, Human, Pair 17; Clinical Trials, Phase III as Topic; Cyclophosphamide; Disease-Free Survival; DNA Topoisomerases, Type II; DNA-Binding Proteins; Fluorescent Dyes; Fluorouracil; Genetic Markers; Humans; In Situ Hybridization, Fluorescence; Methotrexate; Neoplasm Recurrence, Local; Neoplasms; Poly-ADP-Ribose Binding Proteins; Prognosis; Proportional Hazards Models; Treatment Outcome | 2015 |
Dark Agouti rat model of chemotherapy-induced mucositis: establishment and current state of the art.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Fluorouracil; Humans; Irinotecan; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mucositis; Rats | 2015 |
Comparing Role of Two Chemotherapy Regimens, CMF and Anthracycline-Based, on Breast Cancer Survival in the Eastern Mediterranean Region and Asia by Multivariate Mixed Effects Models: a Meta-Analysis.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Asia; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Mediterranean Region; Methotrexate; Survival Analysis | 2015 |
Defining optimal duration and predicting benefit from chemotherapy in patients with luminal-like subtypes.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Taxoids | 2015 |
Laser-Assisted Drug Delivery.
Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Aminolevulinic Acid; Aminoquinolines; Analgesics; Antibodies; Antineoplastic Agents; Ascorbic Acid; Cyclopropanes; Dermatologic Agents; Drug Delivery Systems; Fluorouracil; Humans; Imiquimod; Immunotherapy; Laser Therapy; Methotrexate; Minoxidil; Permeability; Photosensitizing Agents; Polyesters; RNA, Small Interfering; Skin; Timolol; Vaccines | 2016 |
The Efficacy and Safety of First-line Chemotherapy in Advanced Esophagogastric Cancer: A Network Meta-analysis.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Camptothecin; Capecitabine; Cisplatin; Disease-Free Survival; Drug Combinations; Esophageal Neoplasms; Esophagogastric Junction; Fluorouracil; Humans; Irinotecan; Methotrexate; Network Meta-Analysis; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Randomized Controlled Trials as Topic; Stomach Neoplasms; Survival Rate; Taxoids; Tegafur | 2016 |
A network meta-analysis for toxicity of eight chemotherapy regimens in the treatment of metastatic/advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Cyclophosphamide; Docetaxel; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Paclitaxel; Randomized Controlled Trials as Topic; Taxoids; Treatment Outcome | 2016 |
Combination of metformin with chemotherapeutic drugs via different molecular mechanisms.
Topics: Androgen Antagonists; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Deoxycytidine; Estrogen Receptor Modulators; Fluorouracil; Gemcitabine; Humans; Metformin; Methotrexate; Neoplasms; Paclitaxel; Tubulin Modulators | 2017 |
Postmenopausal choriocarcinoma: a rare case report and review of the literature.
Topics: Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Chorionic Gonadotropin, beta Subunit, Human; Cyclophosphamide; Dactinomycin; Etoposide; Female; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Postmenopause; Vaginal Neoplasms; Vincristine | 2018 |
Intralesional therapy for the treatment of keratoacanthoma.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Dermatologic Agents; Fluorouracil; Humans; Injections, Intralesional; Interferon-alpha; Keratoacanthoma; Methotrexate; Skin Neoplasms | 2019 |
Treatment of Solitary Keratoacanthoma of the Nose With Intralesional Methotrexate and Review of the Literature
Topics: Antineoplastic Agents; Biopsy; Bleomycin; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Injections, Intralesional; Keratoacanthoma; Methotrexate; Middle Aged; Mohs Surgery; Nose Neoplasms; Skin; Skin Neoplasms; Treatment Outcome | 2019 |
The role of therapeutic drug monitoring in the management of safety of anticancer agents: a focus on 3 cytotoxics.
Topics: Antineoplastic Agents; Busulfan; Dose-Response Relationship, Drug; Drug Monitoring; Fluorouracil; Humans; Methotrexate; Neoplasms; Practice Guidelines as Topic; Precision Medicine | 2019 |
Vitamin D and Other Differentiation-promoting Agents as Neoadjuvants for Photodynamic Therapy of Cancer.
Topics: Administration, Oral; Aminolevulinic Acid; Cell Differentiation; Fluorouracil; Humans; Methotrexate; Neoadjuvant Therapy; Neoplasms; Photochemotherapy; Photosensitizing Agents; Vitamin D | 2020 |
Relationships between pathological factors and long-term outcomes in patients enrolled in two prospective randomized controlled trials comparing the efficacy of oral tegafur-uracil with CMF (N·SAS-BC 01 trial and CUBC trial).
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Neoplasm Recurrence, Local; Prospective Studies; Randomized Controlled Trials as Topic; Tegafur | 2021 |
Experimental Chemotherapy-Induced Mucositis: A Scoping Review Guiding the Design of Suitable Preclinical Models.
Topics: Animals; Antineoplastic Agents; Fluorouracil; Humans; Irinotecan; Methotrexate; Mice; Mucositis; Rabbits; Rats; Reproducibility of Results; Stomatitis; Swine; Zebrafish | 2022 |
1079 trial(s) available for fluorouracil and methotrexate
| Article | Year |
|---|---|
Short-course cyclical chemotherapy in advanced breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Vincristine | 1977 |
Multimodal therapy for histological stage-II breast cancer. Multicentre Breast Cancer Chemotherapy Group.
Topics: Adult; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; United Kingdom; Vincristine | 1977 |
Adjuvant hormono-chemotherapy in operable breast cancer.
Topics: Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Postoperative Care; Prednisone; Tamoxifen | 1978 |
Multimodal therapy from stage-II breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Injections, Intravenous; Methotrexate; Middle Aged; Neoplasm Staging; Vincristine | 1978 |
Treatment of early breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Postoperative Care; Prednisone; Time Factors; Vincristine | 1978 |
Combination chemotherapy pilot studies in head and neck squamous cell cancer.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Pilot Projects; Time Factors | 1979 |
Advanced ovarian adenocarcinoma. A prospective clinical trial of melphalan (L-PAM) versus combination chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Altretamine; Antineoplastic Agents; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Ovarian Neoplasms; Prospective Studies | 1978 |
Histologic grade in advanced ovarian cancer.
Topics: Altretamine; Cell Differentiation; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Ovarian Neoplasms; Prognosis | 1979 |
Adrenalectomy-oophorectomy and combined chemotherapy for carcinoma of the breast with metastases.
Topics: Adenocarcinoma; Adrenalectomy; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Castration; Clinical Trials as Topic; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Random Allocation; Thiotepa; Vincristine | 1979 |
[The combined treatment of bronchial carcinoma (author's transl)].
Topics: Adenocarcinoma; Aged; Bronchial Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Vinblastine | 1975 |
Phase II study of combination cytotoxic chemotherapy in advanced breast cancer: 2 years' followup.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Peripheral Nervous System Diseases; Vincristine | 1976 |
Conservative treatment of patients with small-cell lung cancer.
Topics: Carcinoma, Small Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Radioisotope Teletherapy; Vinblastine | 1976 |
Chemotherapy of disseminated breast cancer. Current status and prospects.
Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Estrogens, Conjugated (USP); Female; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasm Metastasis; Prednisone; Vincristine | 1977 |
Quadruple chemotherapy versus radiotherapy in treatment of primary hepatocellular carcinoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Aspartate Aminotransferases; Bilirubin; Carcinoma, Hepatocellular; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Prognosis; Vincristine | 1977 |
Combination modality therapy in lung cancer: a survival study showing beneficial results of AMCOF (adriamycin, methotrexate, cyclophosphamide, oncovin and 5-fluorouracil).
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Bone Marrow; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Time Factors; Vincristine | 1978 |
Randomized sequential hormonal therapy vs adrenalectomy for metastatic breast carcinoma.
Topics: Adrenalectomy; Adult; Breast Neoplasms; Castration; Clinical Trials as Topic; Cyclophosphamide; Diethylstilbestrol; Drug Therapy, Combination; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Time Factors | 1977 |
[Combination antimetabolite-alkylating agent-vinblastine in the treatment of advanced breast cancer].
Topics: Adult; Aged; Alkylating Agents; Antimetabolites; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Time Factors; Vinblastine | 1977 |
The CMF program for operable breast cancer with positive axillary nodes. Updated analysis on the disease-free interval, site of relapse and drug tolerance.
Topics: Amenorrhea; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukopenia; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Middle Aged; Thrombocytopenia | 1977 |
Combined chemo- and hormonal therapy in advanced breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Castration; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Diethylstilbestrol; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Medroxyprogesterone; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Vincristine | 1977 |
A comparison of cyclophosphamide, adriamycin, 5-fluorouracil (CAF) and cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, prednisone (CMFVP) in patients with metastatic breast cancer: a Southeastern Cancer Study Group project.
Topics: Agranulocytosis; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prednisone; Skin Neoplasms; Vincristine; Vomiting | 1977 |
Chemotherapy of advanced soft-tissue sarcomas in adults.
Topics: Adult; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Cyclophosphamide; Dacarbazine; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Immunotherapy; Methotrexate; Neoplasm Metastasis; Sarcoma; Soft Tissue Neoplasms; Vincristine | 1977 |
Adjuvant chemotherapy in the primary management of breast cancer.
Topics: Adult; Aged; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Survival; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Recurrence; Research Design | 1977 |
Surgery and adjuvant chemotherapy in the treatment of operable breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Bone Marrow; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Metastasis; Recurrence | 1977 |
Chemotherapy of metastatic breast cancer in postmenopausal women: a controlled trial of cyclophosphamide versus a five-drug combination of cyclophosphamide, vincristine, methotrexate, 5-fluorouracil and prednisone.
Topics: Aged; Antineoplastic Agents; Bone Marrow; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Remission, Spontaneous; Time Factors; Vincristine | 1977 |
Combination chemotherapy in advanced breast cancer.: a randomized trial comparing a three-vs a five-drug program.
Topics: Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Double-Blind Method; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Neoplasm Metastasis; Prednisone; Vincristine | 1977 |
Treatment of metastatic breast cancer with adriamycin-cyclophosphamide induction followed by alternating combination therapy.
Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis | 1977 |
Adjuvant combination chemotherapy in primary mammary carcinoma: the CMF program.
Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Leukopenia; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Time Factors | 1977 |
A randomized comparative trial of adriamycin versus methotrexate in combination drug therapy.
Topics: Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Remission, Spontaneous; Time Factors | 1978 |
Activity of adriamycin in metastatic breast cancer resistant to a combination regimen with cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, and prdnisone.
Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Resistance; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Vincristine | 1978 |
Adjuvant chemoimmunotherapy with LMF + BCG in node-negative and node-positive breast cancer patients. Intermediate report of a randomized trial in 242 patients.
Topics: Administration, Oral; Aged; BCG Vaccine; Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Neoplasm Recurrence, Local | 1978 |
[Chemotherapy in curable breast cancer].
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged | 1978 |
Phase II trial of a combination of cyclosphamide, vincristine, and methotrexate in advanced colorectal carcinoma.
Topics: Adult; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Rectal Neoplasms; Vincristine | 1978 |
Combined cytotoxic and progestogen therapy for advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Bone Marrow; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Heart Failure; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Norethindrone; Remission, Spontaneous; Time Factors; Vincristine | 1978 |
Chemotherapy of advanced breast cancer. Results of a controlled trial comparing two three-drug regimens.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Random Allocation; Remission, Spontaneous; Vincristine | 1978 |
Adriamycin versus methotrexate in five-drug combination chemotherapy for advanced breast cancer: a randomized trial.
Topics: Antineoplastic Agents; Bone Marrow; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Peripheral Nerves; Prednisone; Remission, Spontaneous; Time Factors; Vincristine | 1978 |
Sequential chemoimmunotherapy of colorectal cancer: evaluation of methotrexate, Baker's Antifol and levamisole.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Colonic Neoplasms; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Levamisole; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms; Remission, Spontaneous; Semustine; Time Factors; Triazines | 1978 |
Are surgical adjuvant trials altering the course of breast cancer?
Topics: Adult; Aged; Antineoplastic Agents; BCG Vaccine; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovary; Receptors, Estrogen | 1978 |
[Combined drug treatment of far-advanced forms of breast cancer].
Topics: Antineoplastic Agents; Breast Neoplasms; Castration; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Hexestrol; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Neoplasm Metastasis; Prednisolone; Testosterone; Time Factors; Vincristine | 1978 |
Low dose chemotherapy of metastatic breast cancer with cyclophosphamide, adriamycin, methotrexate, 5-fluorouracil (CAMF) versus sequential cyclophosphamide, methotrexate, 5-fluorouracil (CMF) and adriamycin.
Topics: Antineoplastic Agents; Bone Marrow; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Remission, Spontaneous | 1979 |
Sequential combination chemotherapy in advanced breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Time Factors; Vincristine | 1978 |
[Preliminary results of a continuous study protocol with adjuvant chemotherapy in primary operable breast carcinoma].
Topics: Adult; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged | 1978 |
[Joint radiation and chemotherapy of squamous cell lung cancer].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Gamma Rays; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Radiotherapy; Radiotherapy Dosage | 1979 |
Preliminary report of a clinical trial of the treatment of patients with advanced stage III and IV ovarian cancer with melphalan, 5-fluorouracil, and methotrexate in combination and sequentially: a study of the Clinical Trials Group of the National Cancer
Topics: Adult; Aged; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Ovarian Neoplasms; Remission, Spontaneous; Time Factors | 1979 |
Controlled prospective trial of combination chemotherapy with cyclophosphamide, adriamycin, and 5-fluorouracil for the treatment of advanced ovarian cancer: a preliminary report.
Topics: Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Organothiophosphorus Compounds; Ovarian Neoplasms; Remission, Spontaneous | 1979 |
Pilot study on adjuvant chemotherapy and hormonal therapy for irradiated inoperable breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Pilot Projects; Tamoxifen; Vincristine | 1978 |
Adjuvant therapy of stage II, III breast cancer.
Topics: Antineoplastic Agents; BCG Vaccine; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Menopause; Methotrexate; Neoplasm Staging | 1978 |
Levamisole: as adjuvant to cyclic chemotherapy in breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Levamisole; Melphalan; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis | 1978 |
The dilemma regarding postoperative chemotherapy in primary carcinoma of the colon.
Topics: Antineoplastic Agents; BCG Vaccine; Breast Neoplasms; Carcinoma; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Mycobacterium bovis; Neoplasm Metastasis; Postoperative Care; Semustine; Vincristine | 1979 |
Adjuvant chemotherapy in breast cancer--Swiss co-operative studies.
Topics: Antineoplastic Agents; BCG Vaccine; Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Recurrence; Time Factors | 1979 |
Chemotherapy in advanced gastric cancer: a controlled, prospective, randomised multi-centre study.
Topics: Adenocarcinoma; Adult; Aged; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mitomycins; Prospective Studies; Random Allocation; Stomach Neoplasms; Vincristine | 1979 |
Preliminary 3-year results of 12 versus 6 cycles of surgical adjuvant CMF in premenopausal breast cancer.
Topics: Adult; Antineoplastic Agents; Bone Marrow; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Remission, Spontaneous; Time Factors | 1979 |
Hormonal study in patients developing amenorrhea during adjuvant chemotherapy for breast cancer.
Topics: Adult; Aged; Amenorrhea; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Estradiol; Female; Fluorouracil; Hormones; Humans; Luteinizing Hormone; Methotrexate; Middle Aged; Ovary; Prolactin; Thyrotropin | 1979 |
[Adriamycin-combination chemotherapy with or without immune stimulation by corynebacterium parvum in metastasizing carcinoma of the breast (author's transl)].
Topics: Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunotherapy; Methotrexate; Middle Aged; Neoplasm Metastasis; Propionibacterium acnes; Time Factors; Vincristine | 1979 |
Response of metastatic breast cancer to combination chemotherapy according to site.
Topics: Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prednisolone; Vincristine | 1977 |
Four drug combination cytotoxic chemotherapy following surgery for breast cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Prospective Studies; Vincristine | 1978 |
Chemotherapy of advanced breast cancer: a controlled randomized trial of cyclophosphamide versus a four-drug combination.
Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Middle Aged; Vinblastine | 1975 |
Preliminary Results of trials of chemotherapy in advanced ovarian carcinoma.
Topics: Altretamine; Antineoplastic Agents; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Maryland; Melphalan; Methotrexate; National Institutes of Health (U.S.); Ovarian Neoplasms; Prospective Studies; United States | 1975 |
The polychemotherapeutic treatment of advanced breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Mechlorethamine; Methotrexate; Remission, Spontaneous; Time Factors; Vincristine | 1977 |
[Cytostatic treatment of metastasizing breast cancer. A prospective controlled comparison between single drug and multiple drug chemotherapy].
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Prospective Studies; Vincristine | 1977 |
Combination chemotherapy and adriamycin in patients with advanced breast cancer. A Southwest Oncology Group study.
Topics: Alopecia; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Heart; Humans; Leukopenia; Methotrexate; Prednisone; Vincristine; Vomiting | 1976 |
Combination versus sequential five-drug chemotherapy in metastatic carcinoma of the breast.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Vincristine | 1976 |
Immunology and adjuvant chemoimmunotherapy of breast cancer.
Topics: Aged; Animals; Antibodies, Neoplasm; BCG Vaccine; Breast Neoplasms; Carcinoma; Chick Embryo; Cyclophosphamide; Female; Fluorouracil; Humans; Immunotherapy; Lymphatic Metastasis; Male; Melanoma; Methotrexate; Middle Aged; Prospective Studies; Sarcoma | 1976 |
Combination chemotherapy for metastatic breast carcinoma. Prospective comparison of multiple drug therapy with L-phenylalanine mustard.
Topics: Adult; Aged; Antineoplastic Agents; Boston; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Prospective Studies | 1976 |
[Sequential chemotherapy based on the hypothesis of a circadian rhythm of tumor proliferation].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma; Carcinoma, Squamous Cell; Circadian Rhythm; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Granulocytes; Humans; Male; Methotrexate; Middle Aged; Mitosis; Neoplasm Metastasis; Neoplasms; Remission, Spontaneous; Vinblastine | 1975 |
[Chemotherapy of metastasizing breast cancers. Indications and results].
Topics: Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Neoplasm Metastasis; Prednisone; Remission, Spontaneous; Thoracic Neoplasms; Time Factors; Vincristine | 1975 |
Response and survival in advanced breast cancer after two non-cross-resistant combinations.
Topics: Antineoplastic Agents; Blood Cell Count; Blood Platelets; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukocyte Count; Methotrexate; Middle Aged; Neoplasm Metastasis; Prospective Studies; Time Factors; Vincristine | 1976 |
General condition of asymptomatic patients with advanced colorectal cancer receiving palliative chemotherapy. A longitudinal study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Colorectal Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Norway; Palliative Care; Prognosis; Prospective Studies; Quality of Life; Surveys and Questionnaires; Sweden | 1992 |
Quality of life measurements in anti-emetic trials: a discussion of Professor Selby's paper.
Topics: Antiemetics; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Methotrexate; Neoplasms; Palliative Care; Quality of Life; Research Design | 1992 |
[Neoadjuvant chemotherapy in combined treatment of breast cancer].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy, Radical; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Preoperative Care; Prospective Studies; Radiotherapy Dosage; Remission Induction; Thiotepa | 1992 |
[The adjuvant chemotherapy of breast cancer].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy, Radical; Methotrexate; Middle Aged; Neoplasm Staging; Preoperative Care; Russia; Thiotepa; Time Factors | 1992 |
Favorable long-term survival following induction chemotherapy with cisplatin, fluorouracil, and leucovorin and concomitant chemoradiotherapy for locally advanced head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Leucovorin; Male; Methotrexate; Middle Aged; Radiography; Time Factors; Treatment Outcome | 1992 |
Treatment of recurrent head and neck cancer with cisplatin and 5-fluorouracil vs. the same plus bleomycin and methotrexate.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Ear, Middle; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hypertension; Kidney; Leukopenia; Male; Methotrexate; Middle Aged; Nausea; Neoplasm Recurrence, Local; Remission Induction; Survival Rate; Time Factors | 1992 |
Combination chemotherapy and radiation for palliation of hepatocellular carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Drug Evaluation; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Palliative Care; Prospective Studies; Remission Induction; Survival Analysis | 1992 |
Clinical and laboratory evaluation of the myeloprotective effect of medroxyprogesterone acetate in head and neck cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Cell Count; Cisplatin; Fluorouracil; Granulocytes; Head and Neck Neoplasms; Hematopoietic Stem Cells; Humans; Macrophages; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Methotrexate; Mitosis; Vincristine | 1992 |
A phase II trial of biochemical modulation using N-phosphonacetyl-L-aspartate, high-dose methotrexate, high-dose 5-fluorouracil, and leucovorin in patients with adenocarcinoma of unknown primary site.
Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Drug Evaluation; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasms, Unknown Primary; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate; Uridine Triphosphate | 1992 |
Phase II study of epirubicin sequential methotrexate and 5-fluorouracil for advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Diarrhea; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms | 1992 |
Postsurgical adjuvant chemotherapy with or without radiotherapy in women with breast cancer and positive axillary nodes: a South-Eastern Cancer Study Group (SEG) Trial.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Neoplasm Recurrence, Local; Prospective Studies; Survival Analysis | 1992 |
Combination chemotherapy for advanced urothelial-tract carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Urologic Neoplasms | 1992 |
A phase II clinical trial evaluating the use of two sequential, four-drug combination chemotherapy regimens in ambulatory bronchogenic adenocarcinoma patients.
Topics: Adenocarcinoma; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Procarbazine; Radiation Dosage; Remission Induction; Survival Analysis; Vinblastine; Vincristine | 1992 |
[Treatment of digestive system neoplasms by biochemical modulation].
Topics: Antineoplastic Combined Chemotherapy Protocols; Digestive System Neoplasms; Drug Synergism; Fluorouracil; Humans; Leucovorin; Methotrexate | 1992 |
F-MACHOP in advanced aggressive lymphoma.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Fluorouracil; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Neoplasm Staging; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine | 1992 |
Randomized trial of adjuvant chemotherapy for operable breast cancer comparing i.v. CMF to an epirubicin-containing regimen [see comment].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Injections, Intravenous; Methotrexate; Middle Aged; Mitomycin; Neoplasm Recurrence, Local; Thiotepa; Vincristine; Vindesine | 1992 |
Sequential methotrexate and 5-fluorouracil (FU) vs. FU alone in metastatic colorectal cancer. Results of a randomized multicenter trial. The Association of Medical Oncology (AIO) of the German Cancer Society.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Survival Rate | 1992 |
A phase II trial of cyclophosphamide, methotrexate, 5-fluorouracil, and prednisolone rapidly alternating with doxorubicin and vincristine (CMFP/AV) in advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Survival Analysis; Vincristine | 1992 |
Neoadjuvant chemotherapy in 126 operable breast cancers.
Topics: Adjuvants, Pharmaceutic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Preoperative Care; Vincristine | 1992 |
[Value of chemotherapy preceding exclusive conservative loco-regional radiotherapy in breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Radiation Dosage; Thiotepa; Vinblastine | 1992 |
FAMTX versus etoposide, doxorubicin, and cisplatin: a random assignment trial in gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Prospective Studies; Stomach Neoplasms; Survival Analysis | 1992 |
Description of the statistical aspects of a study for advanced colorectal cancer patients.
Topics: Bayes Theorem; Cisplatin; Colorectal Neoplasms; Combined Modality Therapy; Dose-Response Relationship, Drug; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Methotrexate; Survival Rate | 1992 |
Expectancy or primary chemotherapy in patients with advanced asymptomatic colorectal cancer: a randomized trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Survival Rate; Time Factors | 1992 |
Chemotherapy versus tamoxifen versus chemotherapy plus tamoxifen in node-positive, oestrogen-receptor positive breast cancer patients. An update at 7 years of the 1st GROCTA (Breast Cancer Adjuvant Chemo-Hormone Therapy Cooperative Group) trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Neoplasm Proteins; Receptors, Estrogen; Tamoxifen | 1992 |
Neoadjuvant PFL augmented by methotrexate and piritrexim followed by concomitant chemoradiotherapy for advanced head and neck cancer: a feasible and active approach.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Pyrimidines | 1992 |
Swiss adjuvant trials in women with node-negative breast cancer. OSAKO.
Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Chemotherapy, Adjuvant; Chlorambucil; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Recurrence, Local; Risk Factors; Switzerland | 1992 |
Adjuvant CMF for node-negative and estrogen receptor-negative breast cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Patient Compliance; Prospective Studies; Receptors, Estrogen; Risk Factors; Survival Rate | 1992 |
West Midlands Oncology Association trial of adjuvant chemotherapy in node-negative breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Chlorambucil; England; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Odds Ratio; Prognosis; Risk Factors; Survival Rate | 1992 |
Chemotherapy versus observation in high-risk node-negative breast cancer patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Neoplasm Recurrence, Local; Postoperative Care; Prednisone; Receptors, Estrogen; Risk Factors; Survival Rate | 1992 |
Methylprednisolone as antiemetic treatment in breast-cancer patients receiving cyclophosphamide, methotrexate, and 5-fluorouracil: a prospective, crossover, randomized blind study comparing two different dose schedules.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Double-Blind Method; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Middle Aged; Nausea; Prospective Studies; Vomiting | 1992 |
Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: a Southwest Oncology Group study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Logistic Models; Male; Methotrexate; Middle Aged; Proportional Hazards Models; Prospective Studies; Survival Analysis; Treatment Outcome | 1992 |
Cisplatin plus VP-16 combination chemotherapy in advanced refractory breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Synergism; Etoposide; Female; Fluorouracil; Humans; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Middle Aged; Mitomycin; Skin Neoplasms; Time Factors | 1992 |
Dichloromethotrexate, infusional cisplatin, and infusional 5-fluorouracil for locally advanced or metastatic non-small cell lung cancer. A MAOP study.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Drug Evaluation; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Staging; Remission Induction; Survival Rate | 1991 |
Adjuvant chemotherapy in early breast cancer and incidence of new primary malignancies.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Incidence; Methotrexate; Middle Aged; Neoplasms, Multiple Primary; Radiotherapy Dosage; Registries; Sweden; Tamoxifen; Time Factors | 1991 |
Adjuvant chemotherapy and subsequent malignant disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasms, Multiple Primary | 1991 |
MACOP-B vs F-MACHOP in the treatment of high-grade non-Hodgkin's lymphomas.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphoma, Non-Hodgkin; Male; Methotrexate; Prednisolone; Prednisone; Survival Analysis; Vincristine | 1991 |
Platinum-based chemotherapy followed by radiation therapy of locally advanced nasopharyngeal cancer. A retrospective analysis of 39 cases.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Retrospective Studies | 1991 |
The effect of systemic adjuvant chemotherapy on local breast recurrence in node positive breast cancer patients treated by lumpectomy without radiation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy, Segmental; Methotrexate; Neoplasm Recurrence, Local; Prednisone; Tamoxifen; Vincristine | 1992 |
Elevated CA19-9 as the most significant prognostic factor in advanced colorectal carcinoma.
Topics: Adult; Antigens, Tumor-Associated, Carbohydrate; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoembryonic Antigen; Colorectal Neoplasms; Epirubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Neoplasm Staging; Prognosis; Survival Analysis | 1992 |
Polyadenylic-polyuridylic acid plus locoregional and pelvic radiotherapy versus chemotherapy with CMF as adjuvants in operable breast cancer. A 6 1/2 year follow-up analysis of a randomized trial of the French Federation of Cancer Centers (F.F.C.C.).
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Menopause; Methotrexate; Middle Aged; Pelvis; Poly A-U; Prospective Studies; Survival Rate | 1991 |
A randomized trial of chemotherapy (L-PAM vs CMF) and irradiation for node positive breast cancer. Eleven year follow-up of a Piedmont Oncology Association trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Lymphatic Metastasis; Melphalan; Methotrexate; Middle Aged; Survival Rate | 1991 |
Neoadjuvant chemotherapy with cyclophosphamide, doxorubicin and 5-fluorouracil (CAF) or cyclophosphamide, methotrexate and 5-fluorouracil (CMF) in 69 cases of locally advanced (stage IIIb) breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy, Radical; Methotrexate; Middle Aged; Radiotherapy, High-Energy; Survival Analysis | 1991 |
Double-blind randomized cross-over trial comparing methylprednisolone with placebo in chemotherapy-induced nausea and vomiting: a study with special reference to efficacy parameters.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Double-Blind Method; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Middle Aged; Nausea; Placebos; Vomiting | 1991 |
"Classical" CMF versus a 3-weekly intravenous CMF schedule in postmenopausal patients with advanced breast cancer. An EORTC Breast Cancer Co-operative Group Phase III Trial (10808).
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Time Factors | 1991 |
Long-term survival of patients treated with combination chemotherapy for metastatic breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitolactol; Prognosis; Prospective Studies; Time Factors; Vincristine | 1991 |
Effect of chemotherapy with or without buserelin on serum hormone levels in premenopausal women with breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Buserelin; Cyclophosphamide; Doxorubicin; Estradiol; Female; Fluorouracil; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Menstruation; Methotrexate; Middle Aged; Ovary; Time Factors | 1991 |
Long-term survival in ovarian cancer. Mature data from The Netherlands Joint Study Group for Ovarian Cancer.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Netherlands; Ovarian Neoplasms; Prognosis; Time Factors | 1991 |
Oral ondansetron (GR 38032F) for the control of CMF-induced emesis in the outpatient.
Topics: Administration, Oral; Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Imidazoles; Methotrexate; Middle Aged; Ondansetron; Vomiting | 1991 |
Cisplatin, continuous-infusion 5-fluorouracil, and intermediate-dose methotrexate in the treatment of unresectable non-small cell carcinoma of the lung.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Combined Modality Therapy; Drug Evaluation; Female; Fluorouracil; Follow-Up Studies; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Remission Induction; Survival Rate | 1991 |
Systemic adjuvant therapy in women with resected node-negative breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Prognosis; Receptors, Estrogen; Tamoxifen; Time Factors | 1991 |
[Comparative evaluation of 2 schedules of administration of anti- neoplastic drugs by the CMF protocol in disseminated breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Prospective Studies; Remission Induction | 1991 |
Relative importance of dose, body surface area, sex, and age for 5-fluorouracil clearance.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Body Surface Area; Breast Neoplasms; Colonic Neoplasms; Esophageal Neoplasms; Female; Fluorouracil; Half-Life; Humans; Infusions, Intravenous; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Neoplasms; Rectal Neoplasms; Sex Characteristics | 1991 |
Hexamethylmelamine (altretamine): early National Cancer Institute trials.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; National Institutes of Health (U.S.); Neoplasm Staging; Ovarian Neoplasms; United States | 1991 |
Chemotherapy and surgery for locally advanced cancer of the cardia and fundus: phase II study with methotrexate and 5-fluorouracil.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Evaluation; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Stomach Neoplasms | 1991 |
Folate biochemical modulation regimen for the treatment of gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Folic Acid Antagonists; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 1991 |
Biochemical modulation of fluorouracil with leucovorin: confirmatory evidence of improved therapeutic efficacy in advanced colorectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Survival Analysis | 1991 |
Sequential combination of methotrexate (MTX), 5-fluorouracil (FU), and high-dose folinic acid (FA) in advanced colorectal cancer: double biochemical modulation?
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Survival Rate | 1991 |
The F-MACHOP sequential combination chemotherapy regimen in advanced diffuse aggressive lymphomas: long-term results.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Fluorouracil; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Remission Induction; Time Factors; Vincristine | 1991 |
Adjuvant chemotherapy with doxorubicin plus cyclophosphamide, methotrexate, and fluorouracil in the treatment of resectable breast cancer with more than three positive axillary nodes.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Heart Failure; Humans; Infusions, Intravenous; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Survival Analysis | 1991 |
Adjuvant tamoxifen in postmenopausal stage II breast cancer five years on.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Menopause; Methotrexate; Neoplasm Staging; Prospective Studies; Randomized Controlled Trials as Topic; Tamoxifen | 1990 |
Adjuvant chemo-endocrine therapy in postmenopausal women with breast cancer and axillary-node metastases.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Evaluation Studies as Topic; Female; Fluorouracil; Follow-Up Studies; Humans; Menopause; Methotrexate; Prednisone; Randomized Controlled Trials as Topic; Tamoxifen | 1990 |
4-Hydroperoxycyclophosphamide purging of breast cancer from the mononuclear cell fraction of bone marrow in patients receiving high-dose chemotherapy and autologous marrow support: a phase I trial.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplastic Stem Cells; Survival Rate | 1991 |
The influence of drug interval on the effect of methotrexate and fluorouracil in the treatment of advanced colorectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Prognosis; Randomized Controlled Trials as Topic; Time Factors | 1991 |
Levamisole in the adjuvant treatment of colon cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Intestinal Absorption; Levamisole; Methotrexate | 1991 |
Sequential high-dose methotrexate and fluorouracil combined with doxorubicin--a step ahead in the treatment of advanced gastric cancer: a trial of the European Organization for Research and Treatment of Cancer Gastrointestinal Tract Cooperative Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prospective Studies; Remission Induction; Stomach Neoplasms; Survival Analysis | 1991 |
Advanced colorectal carcinoma. A prospective randomized trial of sequential methotrexate, 5-fluorouracil, and leucovorin versus 5-fluorouracil alone.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Prospective Studies; Remission Induction; Survival Rate | 1991 |
A randomised comparative trial of mitozantrone/methotrexate/mitomycin C (MMM) and cyclophosphamide/methotrexate/5 FU (CMF) in the treatment of advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Mitoxantrone; Neoplasm Staging | 1991 |
Cyclophosphamide, methotrexate, and fluorouracil with and without doxorubicin in the adjuvant treatment of resectable breast cancer with one to three positive axillary nodes.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Infusions, Intravenous; Lymphatic Metastasis; Methotrexate; Middle Aged; Patient Compliance | 1991 |
Cisplatin and etoposide as first-line chemotherapy for metastatic breast carcinoma: a prospective randomized trial of the Italian Oncology Group for Clinical Research.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Etoposide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged | 1991 |
Late effects of adjuvant oophorectomy and chemotherapy upon premenopausal breast cancer patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Ovariectomy; Prednisone; Receptors, Estrogen | 1990 |
A comparison of continuation versus late intensification followed by discontinuation of chemotherapy in advanced breast cancer. A prospective randomized trial of the Italian Oncology Group for Clinical Research (G.O.I.R.C.).
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Prospective Studies; Vincristine | 1990 |
Double-blind randomized trial of lorazepam versus placebo with methylprednisolone for control of emesis due to non-cisplatin containing chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Double-Blind Method; Drug Therapy, Combination; Epirubicin; Female; Fluorouracil; Humans; Injections, Intramuscular; Injections, Intravenous; Lorazepam; Methotrexate; Methylprednisolone; Middle Aged; Vomiting | 1990 |
[Therapy of metastatic breast cancer at the Ulm Tumor Center in 1980 and 1990].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Survival Rate; Tumor Stem Cell Assay | 1990 |
[Stage T4 bladder cancer. Impact of neoadjuvant chemotherapy on T4b tumors].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Prognosis; Survival Rate; Urinary Bladder Neoplasms; Urinary Diversion; Vinblastine | 1990 |
Phase II study of deoxydoxorubicin in previously untreated metastatic breast cancer.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Vincristine | 1990 |
Adjuvant therapy in breast cancer.
Topics: Adjuvants, Pharmaceutic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Prednisone; Tamoxifen; Vincristine | 1990 |
Results of neoadjuvant chemotherapy and radiation therapy in the breast-conserving treatment of 250 patients with all stages of infiltrative breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Doxorubicin; Esthetics; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Thiotepa; Vinblastine | 1990 |
Incidence of neuropathy in 395 patients with ovarian cancer treated with or without cisplatin.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Nervous System Diseases; Ovarian Neoplasms; Prospective Studies | 1990 |
Proliferative activity, histological grade and benefit from adjuvant chemotherapy in node positive breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Cyclophosphamide; DNA, Neoplasm; Female; Flow Cytometry; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Menopause; Methotrexate; Prognosis; S Phase | 1990 |
A phase III randomised trial of cistplatinum, methotrextate, cisplatinum + methotrexate and cisplatinum + 5-FU in end stage squamous carcinoma of the head and neck. Liverpool Head and Neck Oncology Group.
Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Nausea; Prospective Studies; Randomized Controlled Trials as Topic; Vomiting | 1990 |
Adjuvant trial of 12 cycles of CMFPT followed by observation or continuous tamoxifen versus four cycles of CMFPT in postmenopausal women with breast cancer: an Eastern Cooperative Oncology Group phase III study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Randomized Controlled Trials as Topic; Recurrence; Remission Induction; Survival Analysis; Tamoxifen | 1990 |
Neoadjuvant chemotherapy or chemotherapy and endocrine therapy in locally advanced breast carcinoma. A prospective, randomized study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prospective Studies; Randomized Controlled Trials as Topic; Receptors, Estrogen; Remission Induction; Tamoxifen; Time Factors | 1990 |
A phase III trial on the therapy of advanced pancreatic carcinoma. Evaluations of the Mallinson regimen and combined 5-fluorouracil, doxorubicin, and cisplatin.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Pancreatic Neoplasms; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate; Thrombocytopenia; Vincristine | 1990 |
A randomized trial comparing 12 weeks versus 36 weeks of adjuvant chemotherapy in stage II breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prednisone; Randomized Controlled Trials as Topic; Tamoxifen; Vincristine | 1990 |
A randomized study comparing two regimens of neoadjuvant and adjuvant chemotherapy in multimodal therapy for locally advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Randomized Controlled Trials as Topic; Remission Induction; Survival Analysis | 1990 |
Chemotherapy versus tamoxifen versus chemotherapy plus tamoxifen in node-positive, estrogen receptor-positive breast cancer patients: results of a multicentric Italian study. Breast Cancer Adjuvant Chemo-Hormone Therapy Cooperative Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Italy; Lymph Nodes; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Multicenter Studies as Topic; Multivariate Analysis; Prospective Studies; Random Allocation; Receptors, Estrogen; Tamoxifen | 1990 |
Effect of patients' expectations of benefit with standard breast cancer adjuvant chemotherapy on participation in a randomized clinical trial: a clinical vignette study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Attitude to Health; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Patient Education as Topic; Physician-Patient Relations; Randomized Controlled Trials as Topic; Survival Analysis | 1990 |
Two months of doxorubicin-cyclophosphamide with and without interval reinduction therapy compared with 6 months of cyclophosphamide, methotrexate, and fluorouracil in positive-node breast cancer patients with tamoxifen-nonresponsive tumors: results from t
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Randomized Controlled Trials as Topic; Survival Analysis; Tamoxifen | 1990 |
Sequential methotrexate, 5-fluorouracil, and leucovorin in metastatic measurable colorectal cancer. Does it work?
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Pilot Projects; Remission Induction | 1990 |
Association of disease-free survival and percent of ideal dose in adjuvant breast chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Levamisole; Menopause; Methotrexate; Retrospective Studies; Survival Analysis | 1990 |
Adjuvant cyclophosphamide, methotrexate, and fluorouracil in patients with axillary node-positive breast cancer: an update of the Guy's/Manchester trial.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy, Modified Radical; Menopause; Menstrual Cycle; Methotrexate; Middle Aged; Survival Rate | 1990 |
Evaluation of radiotherapy in high-risk breast cancer patients: report from the Danish Breast Cancer Cooperative Group (DBCG 82) Trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Denmark; Female; Fluorouracil; Humans; Mastectomy, Simple; Methotrexate; Risk; Survival Analysis; Tamoxifen | 1990 |
cis-platinum-based alternating non-cross-resistant chemotherapy as a first-line treatment in metastatic breast cancer. A phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Drug Resistance; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Peptichemio; Prednisone; Vincristine | 1990 |
A phase II trial of sequential MTx and 5-FU alternated with 4-epidoxorubicin and cisplatin in advanced gastric cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Prognosis; Stomach Neoplasms | 1990 |
High-intensity therapy versus low-intensity therapy in advanced breast cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Random Allocation; Remission Induction; Risk Factors; Survival Rate; Tamoxifen | 1990 |
Adjuvant chemohormonal therapy with cyclophosphamide, methotrexate, 5-fluorouracil, and prednisone (CMFP) or CMFP plus tamoxifen compared with CMF for premenopausal breast cancer patients. An Eastern Cooperative Oncology Group trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prednisone; Prevalence; Prognosis; Randomized Controlled Trials as Topic; Survival Analysis; Tamoxifen | 1990 |
Randomized neo-adjuvant chemotherapy trial for advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Random Allocation; Vinblastine | 1985 |
Chemotherapy for head and neck cancer. Comparison of cisplatin + vinblastine + bleomycin versus methotrexate.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Vinblastine | 1986 |
Rationally designed combination chemotherapy for the treatment of patients with recalcitrant psoriasis.
Topics: Adult; Aged; Azauridine; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1985 |
Randomized study of adjuvant chemotherapy for head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis; Prospective Studies; Random Allocation | 1985 |
A randomized study of adjuvant chemotherapy for cancer of the upper aerodigestive tract.
Topics: Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Fluorouracil; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Pharyngeal Neoplasms; Time Factors | 1986 |
Intracavitary chemotherapy.
Topics: Anthraquinones; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Catheters, Indwelling; Cisplatin; Clinical Trials as Topic; Cytarabine; Doxorubicin; Etoposide; Fluorouracil; Humans; Immunotherapy; Infusions, Parenteral; Melphalan; Methotrexate; Mitomycins; Mitoxantrone; Neoplasms; Organoplatinum Compounds | 1986 |
A randomized trial of combined multidrug chemotherapy and radiotherapy in advanced squamous cell carcinoma of the head and neck. An interim report from the SECOG participants. South-East Co-operative Oncology Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Prospective Studies; Random Allocation; Vincristine | 1986 |
Factors predicting response of end stage squamous cell carcinoma of the head and neck to cisplatinum.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Random Allocation | 1987 |
Prospective computerized simulation of breast cancer: comparison of computer predictions with nine sets of biological and clinical data.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Computer Simulation; Cyclophosphamide; DNA, Neoplasm; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Neovascularization, Pathologic | 1987 |
A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and high-dose leucovorin versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Palliative Care; Prospective Studies; Random Allocation; Rectal Neoplasms | 1987 |
Three-drug combination chemotherapy for advanced urothelial tract carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Transitional Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Peplomycin; Prospective Studies; Urologic Neoplasms | 1987 |
Failure of chemotherapy to prolong life in patients with metastatic prostate cancer who have failed androgen deprivation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Male; Methotrexate; Palliative Care; Prostatic Neoplasms; Time Factors | 1988 |
[Induction chemotherapy of carcinomas of the oral cavity and oropharynx. Feasibility study, levels and factors of response to treatment. Apropos of 135 cases].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Oropharyngeal Neoplasms; Pharyngeal Neoplasms; Prognosis; Remission Induction; Vincristine; Vindesine | 1987 |
Sequential versus alternating chemotherapy and radiotherapy in stage III-IV squamous cell carcinoma of the head and neck: a phase III study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Staging; Random Allocation; Vincristine | 1988 |
A randomized trial of two dose levels of cyclophosphamide, methotrexate, and fluorouracil chemotherapy for patients with metastatic breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Palliative Care; Quality of Life; Random Allocation | 1988 |
Distant recurrence in breast cancer. Survival expectations and first choice of chemotherapy regimen.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Palliative Care; Random Allocation | 1988 |
[Intra-arterial chemotherapy with methotrexate and 5-fluorouracil in extensive locoregional recurrences of cervix cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Methotrexate; Neoplasm Recurrence, Local; Palliative Care; Prospective Studies; Random Allocation; Uterine Cervical Neoplasms | 1988 |
Quality of life during cytostatic therapy for advanced symptomatic colorectal carcinoma: a randomized comparison of two regimens.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Palliative Care; Quality of Life; Random Allocation | 1989 |
Prognostic factors for chemotherapy response and survival using combination chemotherapy as initial treatment of advanced head and neck squamous cell cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Premedication; Prognosis; Vincristine | 1989 |
Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neoplasms; Drug Interactions; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Methotrexate; Palliative Care; Quality of Life; Random Allocation | 1989 |
Morphometric analysis, ploidy and response to chemotherapy in squamous carcinomas of the head and neck.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Flow Cytometry; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Ploidies; Prospective Studies | 1989 |
Radiotherapy, chemotherapy, and tamoxifen as adjuncts to surgery in early breast cancer: a summary of three randomized trials.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy, Modified Radical; Methotrexate; Middle Aged; Multicenter Studies as Topic; Radiotherapy, High-Energy; Random Allocation; Sweden; Tamoxifen | 1989 |
Adjuvant chemotherapy for node-negative breast cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymph Nodes; Mastectomy; Menopause; Methotrexate; Prospective Studies; Randomized Controlled Trials as Topic; Receptors, Estrogen; Thiotepa; Vincristine | 1989 |
Neoadjuvant chemotherapy in the conservative management of breast cancer: a study of 252 patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Random Allocation; Tamoxifen; Thiotepa; Vinblastine | 1989 |
How to improve adjuvant treatment results in postmenopausal patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Diphosphonates; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Menopause; Meta-Analysis as Topic; Methotrexate; Middle Aged; Prednisone; Randomized Controlled Trials as Topic; Retrospective Studies; Survival Rate; Tamoxifen; Vincristine | 1989 |
Adjuvant chemotherapy in operable gastric cancer. 5 year follow-up of first British Stomach Cancer Group trial.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; England; Female; Fluorouracil; Follow-Up Studies; Gastrectomy; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Multicenter Studies as Topic; Neoplasm Staging; Prognosis; Random Allocation; Stomach Neoplasms; Vincristine; Wales; Weight Loss | 1989 |
Conservation therapy of breast cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Recurrence, Local; Pilot Projects; Random Allocation; Tamoxifen | 1989 |
The role of surgery in the combined treatment of locally advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Diethylstilbestrol; Doxorubicin; Female; Fluorouracil; Humans; Mastectomy, Radical; Methotrexate; Middle Aged; Neoplasm Staging | 1989 |
Effective control of CMF-related emesis with high-dose dexamethasone: results of a double-blind crossover trial with metoclopramide and placebo.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Metoclopramide; Middle Aged; Random Allocation; Vomiting | 1989 |
Prolonged adjuvant chemotherapy in breast cancer. The Scandinavian Adjuvant Chemotherapy Study 2.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Immunotherapy; Lymphatic Metastasis; Mastectomy, Modified Radical; Methotrexate; Vincristine | 1989 |
Treatment of stage I breast cancer: the NSABP experience.
Topics: Adult; Breast Neoplasms; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Receptors, Estrogen; Tamoxifen | 1989 |
A randomized clinical trial evaluating sequential methotrexate and fluorouracil in the treatment of patients with node-negative breast cancer who have estrogen-receptor-negative tumors.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Postoperative Care; Random Allocation; Receptors, Estrogen; Receptors, Progesterone | 1989 |
Prolonged disease-free survival after one course of perioperative adjuvant chemotherapy for node-negative breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Lymph Nodes; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Random Allocation; Receptors, Estrogen | 1989 |
Randomized clinical trial of CFP versus CMFP in women with metastatic breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Random Allocation | 1989 |
Castration induced by cytotoxic chemotherapy.
Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Random Allocation | 1989 |
Locally advanced breast cancer: the contribution of cytotoxic and endocrine treatment to radiotherapy. An EORTC Breast Cancer Co-operative Group Trial (10792).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisolone; Prognosis; Random Allocation; Tamoxifen | 1989 |
[Results of cooperative studies on the combined treatment of cancer of the lungs including postoperative polychemotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Pneumonectomy; Postoperative Care; Random Allocation | 1989 |
Neoadjuvant and adjuvant methotrexate, cisplatin, and fluorouracil in multimodal therapy of head and neck cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1989 |
Six-year results of the Eastern Cooperative Oncology Group trial of observation versus CMFP versus CMFPT in postmenopausal patients with node-positive breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Menopause; Methotrexate; Middle Aged; Prednisone; Random Allocation; Receptors, Estrogen; Tamoxifen | 1989 |
An EORTC gastrointestinal (GI) group randomized evaluation of the toxicity of sequential high dose methotrexate and 5-fluorouracil combined with adriamycin (FAMTX) vs 5-fluorouracil, adriamycin and mitomycin (FAM) in advanced gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Evaluation; Europe; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Multicenter Studies as Topic; Random Allocation; Stomach Neoplasms | 1989 |
Adjuvant chemotherapy (CMF) for stage III breast cancer: a randomized trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Menopause; Methotrexate; Middle Aged; Prognosis; Random Allocation | 1989 |
High-dose methotrexate and 5-fluorouracil in patients with advanced colorectal carcinoma. A randomized study of two pretreatment intervals.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Blood; Clinical Trials as Topic; Colorectal Neoplasms; Fluorouracil; Humans; Methotrexate; Random Allocation; Remission Induction; Time Factors | 1989 |
Influence of radiotherapy on the dose of adjuvant chemotherapy in early breast cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Random Allocation | 1989 |
Adjuvant CMFVP versus melphalan for operable breast cancer with positive axillary nodes: 10-year results of a Southwest Oncology Group Study.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy, Modified Radical; Mastectomy, Radical; Melphalan; Methotrexate; Prednisone; Vincristine | 1989 |
[Randomized multicenter trial of sequential methotrexate and 5-fluorouracil versus 5-fluorouracil alone in advanced gastric cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Administration Schedule; Female; Fluorouracil; Humans; Japan; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Nausea; Prospective Studies; Quality of Life; Random Allocation; Remission Induction; Stomach Neoplasms; Vomiting | 1989 |
[The results of a modified FAMeth chemotherapy protocol in metastatic stomach carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Clinical Trials as Topic; Combined Modality Therapy; Doxorubicin; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prospective Studies; Remission Induction; Reoperation; Stomach Neoplasms; Time Factors | 1989 |
Superiority of sequential methotrexate, fluorouracil, and leucovorin to fluorouracil alone in advanced symptomatic colorectal carcinoma: a randomized trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Random Allocation; Remission Induction | 1989 |
The relationship between hormone receptor content and the effect of adjuvant tamoxifen in operable breast cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Random Allocation; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1989 |
Role of adjuvant chemotherapy in male breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Male; Mastectomy, Modified Radical; Mastectomy, Radical; Methotrexate; Middle Aged; Neoplasm Metastasis; Tamoxifen | 1989 |
Systemic therapy in patients with node-negative breast cancer. A commentary based on two National Surgical Adjuvant Breast and Bowel Project (NSABP) clinical trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Methotrexate; Randomized Controlled Trials as Topic; Receptors, Estrogen; Survival Analysis; Tamoxifen | 1989 |
West Midlands Oncology Association trials of adjuvant chemotherapy in operable breast cancer: results after a median follow-up of 7 years. II. Patients without involved axillary lymph nodes.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Combined Modality Therapy; Female; Fluorouracil; Humans; Mastectomy, Simple; Methotrexate; Middle Aged; Randomized Controlled Trials as Topic | 1989 |
Methylprednisolone versus metoclopramide as antiemetic treatment in patients receiving adjuvant cyclophosphamide, methotrexate, 5-fluorouracil (CMF) chemotherapy: a randomized crossover blind study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Metoclopramide; Middle Aged; Randomized Controlled Trials as Topic; Vomiting | 1989 |
The Milan experience with adjuvant chemotherapy in premenopausal breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Italy; Menopause; Methotrexate; Randomized Controlled Trials as Topic; Retrospective Studies; Survival Rate | 1989 |
Adjuvant chemo- and endocrine therapy alone or in combination in premenopausal patients (GABG Trial 1).
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Menopause; Methotrexate; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Risk Factors; Tamoxifen | 1989 |
Scottish adjuvant breast cancer trials: results in pre-menopausal patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Menopause; Methotrexate; Ovariectomy; Prednisone; Randomized Controlled Trials as Topic; Scotland; Survival Rate; Tamoxifen | 1989 |
Adjuvant chemo-endocrine therapy or endocrine therapy alone for postmenopausal patients: Ludwig Studies III and IV.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Menopause; Methotrexate; Multicenter Studies as Topic; Prednisone; Randomized Controlled Trials as Topic; Receptors, Estrogen; Tamoxifen | 1989 |
Chemo- or endocrine adjuvant therapy alone or combined in postmenopausal patients (GABG Trial 1).
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Mastectomy; Menopause; Methotrexate; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Risk Factors; Tamoxifen | 1989 |
Correlation of dose intensity and prognosis in adjuvant chemotherapy: an extended controversy.
Topics: Adjuvants, Pharmaceutic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colorectal Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Meta-Analysis as Topic; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic | 1989 |
Significant survival benefit of node-negative breast cancer patients treated with adjuvant chemotherapy: seven-year results.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aziridines; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Mastectomy; Menopause; Methotrexate; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Risk Factors; Survival Rate; Vincristine | 1989 |
Adjuvant immunotherapy in node-negative patients: results of a Scandinavian study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Corynebacterium; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Immunotherapy; Lymph Nodes; Mastectomy; Methotrexate; Norway; Randomized Controlled Trials as Topic; Sweden | 1989 |
Randomized multicenter 2 x 2-factorial design study of chemo/endocrine therapy in operable, node-positive breast cancer (protocol 2).
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cohort Studies; Combined Modality Therapy; Cyclophosphamide; Evaluation Studies as Topic; Fluorouracil; Germany, West; Humans; Lymph Nodes; Lymphatic Metastasis; Mastectomy; Methotrexate; Multicenter Studies as Topic; Physician's Role; Randomized Controlled Trials as Topic; Research Design; Tamoxifen | 1989 |
Randomized perioperative therapy in operable breast cancer: the Ludwig Trial V.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Mastectomy; Methotrexate; Middle Aged; Multicenter Studies as Topic; Prednisone; Survival Rate; Tamoxifen | 1989 |
Salvage treatments in relapsing resectable breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Fluorouracil; Humans; Mastectomy; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Randomized Controlled Trials as Topic; Tamoxifen | 1989 |
[Mitoxantrone containing multi-drug chemotherapy in the management of malignancies. Collaborative Group for Clinical Trial of Mitoxantrone].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Digestive System Neoplasms; Doxorubicin; Female; Fluorouracil; Humans; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Prospective Studies | 1989 |
Adjuvant chemoimmunotherapy with LMF + BCG in node-negative and node-positive breast cancer patients: 10 year results.
Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Chlorambucil; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy, Modified Radical; Methotrexate; Middle Aged | 1989 |
Combination of cyclophosphamide, adriamycin and platinum (CAP) versus 5-fluorouracil, adriamycin and cyclophosphamide (FAC) as primary treatment in metastatic breast cancer: results of a prospective randomized study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Peptichemio; Prednisone; Prospective Studies; Random Allocation; Vincristine | 1989 |
Treatment of patients with advanced colorectal carcinomas with fluorouracil alone, high-dose leucovorin plus fluorouracil, or sequential methotrexate, fluorouracil, and leucovorin: a randomized trial of the Northern California Oncology Group.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Drug Synergism; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Random Allocation | 1989 |
Endocrine versus endocrine plus five-drug chemotherapy in postmenopausal women with stage II estrogen receptor-positive breast cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy, Modified Radical; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Receptors, Estrogen; Survival Analysis; Tamoxifen; Vincristine | 1989 |
Adjuvant chemotherapy in stage II breast cancer: a brief overview of the NSABP clinical trials.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Staging; Random Allocation | 1985 |
Adjuvant CMF chemotherapy in operable breast cancer: ten years later.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate | 1985 |
Chemotherapy with or without oophorectomy in high-risk premenopausal patients with operable breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Castration; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Menstruation; Methotrexate; Middle Aged; Prednisone; Receptors, Progesterone; Risk | 1985 |
Clinical controlled trial in advanced breast cancer: CMF (cyclophosphamide, methotrexate, 5-fluorouracil) versus CMF + T (cyclophosphamide, methotrexate, 5-fluorouracil, tamoxifen). CMEA Cooperative Treatment Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Tamoxifen | 1985 |
A randomized trial of adjuvant combination chemotherapy with or without prednisone in premenopausal breast cancer patients with metastases in one to three axillary lymph nodes.
Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Menstruation; Methotrexate; Middle Aged; Ovary; Prednisone; Random Allocation | 1985 |
A randomized trial in postmenopausal patients with advanced breast cancer comparing endocrine and cytotoxic therapy given sequentially or in combination. The Australian and New Zealand Breast Cancer Trials Group, Clinical Oncological Society of Australia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Liver Neoplasms; Menopause; Methotrexate; Middle Aged; Prognosis; Random Allocation; Receptors, Estrogen; Tamoxifen; Vincristine | 1986 |
Complete remission at laparotomy: still a gold standard in ovarian cancer?
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Laparotomy; Methotrexate; Ovarian Neoplasms; Random Allocation | 1986 |
Mechanism of action of adjuvant chemotherapy in early breast cancer.
Topics: Adult; Age Factors; Aged; Amenorrhea; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Menopause; Methotrexate; Middle Aged; Postoperative Period; Random Allocation; Receptors, Estrogen; Receptors, Progesterone; Time Factors | 1986 |
Mechanism of action of adjuvant chemotherapy in early breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Random Allocation | 1986 |
Adjuvant chemotherapy combined with tamoxifen in postmenopausal patients with stage II breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Fluorouracil; Humans; Methotrexate; Prospective Studies; Random Allocation; Tamoxifen | 1986 |
Combination adjuvant chemotherapy for node-positive breast cancer. Inadequacy of a single perioperative cycle.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Middle Aged; Preoperative Care; Random Allocation; Tamoxifen | 1988 |
On the safety of perioperative adjuvant chemotherapy with cyclophosphamide, methotrexate and 5-fluorouracil in breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Intraoperative Care; Leucovorin; Mastectomy; Methotrexate; Middle Aged | 1988 |
Adjuvant therapy with tamoxifen in operable breast cancer. 10 year results of the Naples (GUN) study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Follow-Up Studies; Humans; Italy; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Patient Compliance; Prognosis; Random Allocation; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1988 |
A randomized study of inpatient versus outpatient continuous infusion chemotherapy for patients with locally advanced head and neck cancer.
Topics: Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Attitude to Health; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Hospitalization; Humans; Infusion Pumps; Infusions, Intravenous; Methotrexate; Patient Compliance; Random Allocation; Remission Induction | 1989 |
Efficacy of adjuvant chemotherapy in high-risk node-negative breast cancer. An intergroup study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Lymphatic Metastasis; Mastectomy, Radical; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Random Allocation; Receptors, Estrogen; Risk Factors | 1989 |
[Side effects of adjuvant therapies of breast cancer: their significance for the patient].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy, Modified Radical; Methotrexate; Middle Aged; Radiation Injuries; Retrospective Studies | 1989 |
Prospective randomized trial concerning hyper- and normoprolactinemia and the use of bromoergocryptine in patients with metastatic breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bromocriptine; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Humans; Hyperprolactinemia; Medroxyprogesterone; Medroxyprogesterone Acetate; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Prolactin; Vincristine | 1986 |
A Northern California Oncology Group randomized trial of leucovorin plus 5-fluorouracil versus sequential methotrexate, 5-fluorouracil, and leucovorin in patients with advanced colorectal cancer who failed treatment with 5-fluorouracil or 5-fluorodeoxyuri
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colonic Neoplasms; Drug Administration Schedule; Drug Resistance; Floxuridine; Fluorouracil; Humans; Leucovorin; Methotrexate; Rectal Neoplasms | 1987 |
Implementation of the group sequential methodology in a randomized trial in metastatic colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Female; Fluorouracil; Humans; Leukocyte Count; Male; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Random Allocation; Semustine; Streptozocin; Vincristine | 1988 |
Adjuvant therapy for operable breast cancer with medroxyprogesterone acetate alone in postmenopausal patients or in combination with CMF in premenopausal patients.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Menopause; Methotrexate; Middle Aged; Prospective Studies; Recurrence | 1988 |
Cytostatic drug therapy in disseminated colorectal cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Floxuridine; Fluorouracil; Humans; Leucovorin; Methotrexate; Semustine; Vincristine | 1988 |
Long-term survival rates with various chemotherapeutic regimens in stages III and IV ovarian adenocarcinoma. The influence of optimum pretreatment surgical resection.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Cystadenocarcinoma; Dactinomycin; Female; Fluorouracil; Humans; Leucovorin; Methotrexate; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Ovary; Prognosis; Prospective Studies; Random Allocation; Time Factors | 1985 |
Combined therapy in advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Estrogens, Conjugated (USP); Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Tamoxifen | 1985 |
Increasing the response rate to cytotoxic chemotherapy by endocrine means.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Estrogens, Conjugated (USP); Female; Fluorouracil; Humans; Menopause; Methotrexate; Prognosis; Random Allocation; Receptors, Estrogen; Tamoxifen | 1985 |
Systemic cytostatic drug therapy in liver cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Clinical Trials as Topic; Colonic Neoplasms; Doxorubicin; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Methotrexate; Rectal Neoplasms; Semustine; Vincristine | 1986 |
Adjuvant trial for stage II receptor-positive breast cancer: CMF vs. CMF + tamoxifen in a single centre.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Random Allocation; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1988 |
[Chemotherapy of advanced pancreatic cancer with 5-fluorouracil, doxorubicin and high-dose methotrexate].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Pancreatic Neoplasms | 1988 |
More is better.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Methotrexate; Random Allocation | 1988 |
A randomized comparison of haloperidol plus dexamethasone versus prochlorperazine plus dexamethasone in preventing nausea and vomiting in patients receiving chemotherapy for breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Haloperidol; Humans; Methotrexate; Middle Aged; Nausea; Prochlorperazine; Prospective Studies; Random Allocation; Vomiting | 1988 |
Chemotherapy of advanced head and neck cancer: updated results of a randomized trial of the order of administration of sequential methotrexate and 5-fluorouracil.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Random Allocation | 1988 |
Performance of general hospitals in delivering adjuvant chemotherapy to breast cancer patients. G.I.V.I.O. (Interdisciplinary Group for Cancer Care Evaluation), Italy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Delivery of Health Care; Female; Fluorouracil; Hospitals, General; Humans; Italy; Lymphatic Metastasis; Menopause; Methotrexate; Multicenter Studies as Topic; Prospective Studies | 1988 |
[Chemotherapy of inoperable colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Fluorouracil; Humans; Methotrexate | 1988 |
Adjuvant therapy of premenopausal and menopausal high-risk breast cancer patients. Present status of the Danish Breast Cancer Cooperative Group Trials 77-B and 82-B.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy, Simple; Menopause; Methotrexate; Middle Aged; Random Allocation; Risk Factors; Tamoxifen | 1988 |
Postmastectomy irradiation in high-risk breast cancer patients. Present status of the Danish Breast Cancer Cooperative Group trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Levamisole; Mastectomy, Simple; Methotrexate; Random Allocation; Risk Factors; Tamoxifen | 1988 |
Treatment costs of adjuvant cytotoxic therapy in premenopausal breast cancer patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Costs and Cost Analysis; Cyclophosphamide; Denmark; Female; Fluorouracil; Humans; Methotrexate; Random Allocation | 1988 |
The Roswell Park Memorial Institute and Gastrointestinal Tumor Study Group phase III experience with the modulation of 5-fluorouracil by leucovorin in metastatic colorectal adenocarcinoma.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Diarrhea; Fluorouracil; Humans; Leucovorin; Leukopenia; Methotrexate; Random Allocation; Thrombocytopenia | 1988 |
A northern California Oncology Group randomized trial of single agent 5-FU vs. high-dose folinic acid + 5-FU vs. methotrexate + 5-FU + folinic acid in patients with disseminated measurable large bowel cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Random Allocation | 1988 |
[Chemotherapy of breast cancers. Coordinated evolution of therapeutic schemes from 1975 to 1985].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Mitomycin; Mitomycins; Thiotepa; Vincristine; Vindesine | 1986 |
Sequential methotrexate, 5-fluorouracil, and cisplatin in the treatment of recurrent squamous-cell carcinoma of the head and neck: failure of hypertonic saline to reduce the nephrotoxicity of cisplatin.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kidney Diseases; Male; Mannitol; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Random Allocation; Sodium Chloride | 1986 |
[Adjuvant therapy of breast cancer patients].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bromocriptine; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Random Allocation; Tamoxifen; Thiotepa | 1986 |
Adjuvant chemotherapy after conservative surgery plus irradiation versus modified radical mastectomy. Analysis of drug dosing and toxicity.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Mastectomy; Methotrexate; Radiotherapy, High-Energy; Random Allocation | 1987 |
Tolerance of radiotherapy combined with adjuvant chemotherapy in breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Pulmonary Fibrosis; Radiotherapy, High-Energy; Random Allocation | 1987 |
Pharmacokinetic approach to rational therapeutic doses for human tumor-bearing nude mice.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Tolerance; Female; Fluorouracil; Humans; Metabolic Clearance Rate; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Mitomycins; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds; Transplantation, Heterologous; Vincristine | 1988 |
Pharmacokinetics of intravenous and oral cyclophosphamide in the presence of methotrexate and fluorouracil.
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Breast Neoplasms; Chromatography, Gas; Cyclophosphamide; Female; Fluorouracil; Humans; Injections, Intravenous; Methotrexate; Middle Aged; Tablets | 1988 |
Relapse of breast cancer after adjuvant treatment in premenopausal and perimenopausal women: patterns and prognoses.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Neoplasm Recurrence, Local; Prednisone; Prognosis; Prospective Studies; Receptors, Estrogen; Time Factors | 1988 |
Is there a role for perioperative adjuvant therapy in the treatment of early breast cancer?
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Tamoxifen | 1988 |
Methotrexate/fluorouracil scheduling influences normal tissue toxicity but not antitumor effects in patients with squamous cell head and neck cancer: results from a randomized trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Digestive System; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Random Allocation | 1988 |
Hormone-refractory metastatic prostatic cancer treated with methotrexate, cyclophosphamide plus adriamycin, cis-platinum plus 5-fluorouracil plus cyclophosphamide. National Prostatic Cancer Project randomized trial.
Topics: Acid Phosphatase; Alkaline Phosphatase; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Male; Methotrexate; Prostatic Neoplasms; Random Allocation | 1988 |
Sequential 5-fluorouracil, methotrexate, and calcium leucovorin in metastatic colorectal cancer.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Rectal Neoplasms | 1988 |
Systemic therapy of colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Colonic Neoplasms; Drug Synergism; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Leucovorin; Methotrexate; Neoplasm Metastasis; Rectal Neoplasms | 1988 |
An intensive, five course, alternating combination chemotherapy induction regimen used in patients with advanced, unresectable head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged | 1988 |
Chemotherapy of advanced colorectal cancer. A randomized trial of sequential methotrexate and 5-fluorouracil.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Random Allocation; Rectal Neoplasms; Time Factors | 1987 |
Methylprednisolone for the control of CMF-induced emesis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Middle Aged; Random Allocation; Vomiting | 1987 |
[Intra-arterial chemotherapy in advanced ovarian cancer. 2. Technic, results, complications].
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Methotrexate; Neoplasm Metastasis; Ovarian Neoplasms; Random Allocation; Vinblastine | 1987 |
[Intra-arterial chemotherapy in advanced ovarian cancer. 1. Study conditions and prognostic factors].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Methotrexate; Ovarian Neoplasms; Random Allocation; Vincristine | 1987 |
Double-blind controlled trial of the antiemetic efficacy and toxicity of methylprednisolone (MP), metoclopramide (MTC) and domperidone (DMP) in breast cancer patients treated with i.v. CMF.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Domperidone; Double-Blind Method; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Metoclopramide; Middle Aged; Nausea; Vomiting | 1987 |
A randomized, prospective, comparative, multicentre trial of a single combination versus alternating combinations of antitumour drugs in advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prospective Studies; Random Allocation; Vincristine; Vindesine | 1987 |
[Controlled prospective study of chemotherapy in advanced ovarian cancer--cyclophosphamide monochemotherapy versus polychemotherapy with adriamycin, cyclophosphamide, 5-fluorouracil and methotrexate].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms; Prospective Studies | 1987 |
Recurrence patterns in a prospective study of patients with stage II breast cancer treated with endocrine-chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Prospective Studies; Random Allocation; Tamoxifen | 1987 |
Comparison of different trials of adjuvant chemotherapy in stage II breast cancer using a natural history data base.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Information Systems; Lymphatic Metastasis; Medical Records; Melphalan; Methotrexate; Middle Aged; Postoperative Care; Prednisone; Random Allocation; Time Factors; Vincristine | 1987 |
Development and use of a natural history data base of breast cancer studies.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Information Systems; Lymphatic Metastasis; Mastectomy; Medical Records; Methotrexate; Middle Aged; Postoperative Care; Prognosis; Time Factors | 1987 |
Sequential administration of cyclophosphamide, methotrexate, 5-fluorouracil, and folinic acid as salvage treatment in metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Synergism; Female; Fluorouracil; Humans; Leucovorin; Methotrexate; Middle Aged; Neoplasm Metastasis; Time Factors | 1987 |
Evidence of a castration-mediated effect of adjuvant cytotoxic chemotherapy in premenopausal breast cancer.
Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Menopause; Menstrual Cycle; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Ovariectomy; Prognosis; Prospective Studies; Random Allocation; Receptors, Estrogen; Time Factors | 1987 |
Applications of dose intensity to problems in chemotherapy of breast and colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Fluorouracil; Humans; Methotrexate; Random Allocation; Rectal Neoplasms | 1987 |
Alternating versus sequential therapy in advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Vincristine | 1987 |
The thrombogenic effect of anticancer drug therapy in women with stage II breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Pulmonary Embolism; Random Allocation; Tamoxifen; Thrombosis; Time Factors; Vincristine | 1988 |
Combined treatment including postoperative chemotherapy in lung cancer patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Staging; Random Allocation; Statistics as Topic | 1988 |
Methylprednisolone versus metoclopramide for prevention of nausea and vomiting in breast cancer patients treated with intravenous cyclophosphamide methotrexate 5-fluorouracil: a double-blind randomized study.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Double-Blind Method; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Metoclopramide; Middle Aged; Nausea; Random Allocation; Vomiting | 1988 |
Comparison of methotrexate and sequential methotrexate-5-fluorouracil for patients with recurrent squamous cell carcinoma of the oral cavity.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Recurrence, Local; Prospective Studies; Random Allocation | 1987 |
Clinical studies of biochemical modulation of 5-fluorouracil by leucovorin in patients with advanced colorectal cancer by the North Central Cancer Treatment Group and Mayo Clinic.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Colonic Neoplasms; Dose-Response Relationship, Drug; Fluorouracil; Hematopoiesis; Humans; Leucovorin; Methotrexate; Prospective Studies; Rectal Neoplasms | 1987 |
Prospective evaluation of carcinoembryonic antigen levels and alternating chemotherapeutic regimens in metastatic breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoembryonic Antigen; Clinical Laboratory Techniques; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Fluoxymesterone; Follow-Up Studies; Humans; Methotrexate; Mitolactol; Neoplasm Metastasis; Prednisone; Prognosis; Prospective Studies; Random Allocation; Tamoxifen; Vincristine | 1986 |
Comparison of CAF versus CMFP in metastatic breast cancer: analysis of prognostic factors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Humans; Leukocyte Count; Methotrexate; Prednisone | 1986 |
Prednimustine in advanced breast cancer: a review.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Leukocyte Count; Melphalan; Methotrexate; Prednimustine; Time Factors | 1986 |
Combination chemotherapy compared to tamoxifen as initial therapy for stage IV breast cancer in elderly women.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Creatinine; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Metabolic Clearance Rate; Methotrexate; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Random Allocation; Receptors, Estrogen; Tamoxifen | 1986 |
Long-term survival following relapse after 5-FU but not CMF adjuvant breast cancer therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Body Weight; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Neoplasm Recurrence, Local; Prognosis; Random Allocation; Time Factors | 1986 |
A randomized trial of two regimens of cyclophosphamide, methotrexate, 5-fluorouracil, and prednisone in advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Random Allocation | 1986 |
Sequential MTX and 5-FU: advance or myth?
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Clinical Trials as Topic; Fluorouracil; Head and Neck Neoplasms; Humans; Leukemia L1210; Methotrexate; Mice | 1986 |
Etoposide (VP-16-213) and cis-dichlorodiammineplatinum (DDP) in advanced breast carcinoma resistant to previous chemotherapy.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Vincristine | 1986 |
Local control and survival in early breast cancer: the Milan trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Italy; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Methotrexate; Neoplasm Recurrence, Local; Random Allocation; Time Factors | 1986 |
Intraperitoneal chemotherapy: a review.
Topics: Abdominal Neoplasms; Antineoplastic Agents; Cisplatin; Clinical Trials as Topic; Cytarabine; Doxorubicin; Evaluation Studies as Topic; Fluorouracil; Humans; Injections, Intraperitoneal; Liver; Mathematics; Melphalan; Methotrexate; Peritoneum | 1986 |
Adjuvant chemo-immunotherapy in stage II carcinoma of the breast.
Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Cell Line; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Hepatitis B; Humans; Immunotherapy; Lymphatic Metastasis; Methotrexate; Middle Aged; Research Design; Vaccines | 1986 |
Adriamycin, vincristine, cyclophosphamide and 5-fluorouracil (AVCF) compared with cyclophosphamide, methotrexate and 5-fluorouracil (CMF) in premenopausal breast carcinoma. Personal results.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Random Allocation; Vincristine | 1986 |
Analysis of dose intensity for adjuvant chemotherapy trials in stage II breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymph Nodes; Menopause; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Prognosis; Random Allocation; Statistics as Topic; Vincristine | 1986 |
Sequential methotrexate-fluorouracil: the role of leucovorin in improving tumor response.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Synergism; Fluorouracil; Humans; Leucovorin; Methotrexate | 1986 |
Perioperative and conventionally timed chemotherapy in operable breast cancer: the Ludwig Breast Cancer Study V.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Methotrexate; Middle Aged; Random Allocation | 1986 |
Adjuvant therapy for breast cancer: a brief overview of the NSABP experience and some thoughts on neoadjuvant chemotherapy.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Methotrexate; Middle Aged; Receptors, Estrogen; Tamoxifen | 1986 |
Preoperative (neoadjuvant) chemotherapy for breast cancer: outline of the British Columbia Trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Breast Neoplasms; Cell Division; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Random Allocation; Receptors, Estrogen | 1986 |
Perioperative adjuvant chemotherapy of breast cancer: the Scandinavian experience.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Immunotherapy; Methotrexate; Middle Aged; Patient Dropouts; Prognosis; Random Allocation | 1986 |
A clinical trial of homoharringtonine in the treatment of advanced breast cancer.
Topics: Adult; Aged; Alkaloids; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Harringtonines; Homoharringtonine; Humans; Methotrexate; Middle Aged | 1986 |
[Prospective randomized study of the efficacy of adjuvant hormone therapy in patients with breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Diethylstilbestrol; Female; Fluorouracil; Humans; Levodopa; Menopause; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Prospective Studies; Random Allocation; Tamoxifen | 1986 |
Immediate and long-term toxicity of adjuvant chemotherapy regimens containing doxorubicin in trials at M.D. Anderson Hospital and Tumor Institute.
Topics: Adult; Alopecia; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; United States | 1986 |
Swiss adjuvant trial (OSAKO 06/74) with chlorambucil, methotrexate, and 5-fluorouracil plus BCG in node-negative breast cancer patients: nine-year results.
Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Switzerland | 1986 |
Emerging modalities for adjuvant therapy of breast cancer: neoadjuvant chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Pilot Projects; Preoperative Care; Random Allocation | 1986 |
Systemic adjuvant therapy in treatment of primary operable breast cancer: National Surgical Adjuvant Breast and Bowel Project experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Mastectomy; Melphalan; Methotrexate; Middle Aged; Tamoxifen | 1986 |
Current status of Milan adjuvant chemotherapy trials for node-positive and node-negative breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Italy; Lymph Nodes; Methotrexate; Middle Aged; Prednisone; Receptors, Estrogen; Retrospective Studies | 1986 |
Adjuvant therapy of breast cancer: Southwest Oncology Group studies.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Melphalan; Methotrexate; Middle Aged; Prednisone; Vincristine | 1986 |
Postoperative chemotherapy and chemohormonal therapy in women with node-positive breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Methotrexate; Middle Aged; Postoperative Period; Prednisone; Receptors, Estrogen; Tamoxifen | 1986 |
Analysis of dose intensity for chemotherapy in early (stage II) and advanced breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Humans; Lymph Nodes; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Vincristine | 1986 |
Duration of therapy in adjuvant chemotherapy trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymph Nodes; Mastectomy; Methotrexate; Time Factors | 1986 |
Value of cyclophosphamide or melphalan as combined chemotherapy in hormonally unresponsive prostatic carcinoma.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Fluorouracil; Humans; Male; Melphalan; Methotrexate; Prednisone; Prostatic Neoplasms; Random Allocation; Vincristine | 1986 |
Hyperglycemic complications associated with adjuvant chemotherapy of breast cancer. A cancer and leukemia group B (CALGB) study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Humans; Hyperglycemia; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Vincristine | 1986 |
Adjuvant chemotherapy for high-risk squamous-cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Neck Dissection; Neoplasm Metastasis; Patient Compliance; Radiography | 1987 |
Combined modality treatment of locally advanced breast cancer: adjuvant combination chemotherapy with and without doxorubicin.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged | 1987 |
[Intra-arterial chemotherapy in advanced ovarian cancers. 2. Therapeutic results in relation to prognostic factors].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Methotrexate; Neoplasm Staging; Ovarian Neoplasms; Prognosis; Reoperation; Vincristine | 1987 |
Second malignancies after CMF for resectable breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Fluorouracil; Follow-Up Studies; Humans; Italy; Mastectomy; Methotrexate; Neoplasms, Multiple Primary; Risk | 1987 |
Chemotherapy versus chemoimmunotherapy (CAF v CAFVP v CMF each +/- MER) for metastatic carcinoma of the breast: a CALGB study. Cancer and Leukemia Group B.
Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Bone Neoplasms; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Immunotherapy; Methotrexate; Middle Aged; Prednisone; Prognosis; Random Allocation; Vincristine | 1987 |
Improving the quality of life during chemotherapy for advanced breast cancer. A comparison of intermittent and continuous treatment strategies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Prednisone; Quality of Life; Random Allocation | 1987 |
Androgen depletion and repletion as a means of potentiating the effect of cytotoxic chemotherapy in advanced prostate cancer.
Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Synergism; Fluorouracil; Fluoxymesterone; Humans; Hydrocortisone; Male; Methotrexate; Orchiectomy; Prostatic Neoplasms; Random Allocation; Spinal Cord Compression | 1987 |
Age as a prognostic factor in recurrent breast cancer.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Ovariectomy; Prednisone; Prognosis; Time Factors; Vincristine | 1986 |
Adjuvant treatment for early breast cancer: the Ludwig breast cancer studies.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Prednisone; Receptors, Estrogen; Switzerland; Tamoxifen | 1986 |
A new endpoint for the assessment of adjuvant therapy in postmenopausal women with operable breast cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Prednisone; Quality of Life; Statistics as Topic; Tamoxifen | 1986 |
A randomized study of intensive versus moderate chemotherapy programs in metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Random Allocation; Receptors, Estrogen; Vincristine | 1987 |
Adjuvant chemo- and hormonal therapy in locally advanced breast cancer: a randomized clinical study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymph Nodes; Menopause; Methotrexate; Vincristine | 1985 |
Evaluation of the antiemetic activity of bromopride in cancer patients treated with i.v. CMF.
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Metoclopramide; Middle Aged | 1985 |
A randomized trial of CMF versus CMFVP as adjuvant chemotherapy in women with node-positive stage II breast cancer: a CALGB Study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Random Allocation; Vincristine | 1985 |
Adjuvant chemotherapy for operable breast cancer with positive axillary nodes: a comparison of CMFVP versus L-PAM.
Topics: Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Nodes; Melphalan; Methotrexate; Prednisone; Vincristine | 1985 |
Adjuvant therapy for breast cancer with positive axillary nodes designed according to estrogen receptor status.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Nodes; Methotrexate; Prednisone; Random Allocation; Receptors, Estrogen; Tamoxifen; Vincristine | 1985 |
Adjuvant chemotherapy in postmenopausal women: results of sequential noncross-resistant regimens.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Random Allocation; Vincristine | 1985 |
Adjuvant chemotherapy for breast cancer. Implications of clinical trials.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Melphalan; Menopause; Methotrexate; Neoplasm Metastasis; Prednisone; Random Allocation; Vincristine | 1985 |
Adjuvant chemotherapy of breast cancer: a promising experiment or standard practice?
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Menopause; Methotrexate; Prednisone; Prognosis; Tamoxifen; Vincristine | 1985 |
Adjuvant CMFP versus CMFP plus tamoxifen versus observation alone in postmenopausal, node-positive breast cancer patients: three-year results of an Eastern Cooperative Oncology Group study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Diabetes Mellitus, Type 1; Female; Fluorouracil; Hematologic Diseases; Humans; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Multiple Primary; Obesity; Prednisone; Prognosis; Random Allocation; Receptors, Estrogen; Risk; Tamoxifen | 1985 |
Adjuvant systemic therapy for resectable breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Castration; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Immunotherapy; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Prognosis; Research Design; Tamoxifen | 1985 |
A randomized controlled trial of prophylactic cytotoxic chemotherapy in potentially curable breast cancer.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Humans; Melphalan; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Patient Compliance; Random Allocation | 1985 |
[Postoperative radio- and/or chemotherapy in ovarian stage III cancers. Results of a prospective randomized study].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Castration; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Hysterectomy; Methotrexate; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Prognosis; Radiotherapy Dosage; Vincristine | 1985 |
Combined cytotoxic and endocrine therapy in postmenopausal patients with advanced breast cancer. A randomized study of CMF vs CMF plus tamoxifen.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Random Allocation; Tamoxifen | 1985 |
Dose intensity in chemotherapy of metastatic breast cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Statistics as Topic | 1985 |
Comparison of CAF versus CMFP in metastatic breast cancer: analysis of prognostic factors.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Prognosis; Random Allocation; Time Factors | 1985 |
An evaluation of the effect of vincristine added to cyclophosphamide, 5-fluorouracil, methotrexate, and prednisone in advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Prognosis; Time Factors; Vincristine | 1985 |
Aggressive adriamycin-containing regimen (PM-FAC) in estrogen receptor-negative disseminated breast cancer. Results of a Southwest Oncology Group trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Meningeal Neoplasms; Methotrexate; Prednisone; Receptors, Estrogen; Time Factors | 1985 |
Chemotherapy versus chemotherapy plus hormonotherapy in postmenopausal advanced breast cancer patients. A randomized trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Medroxyprogesterone; Menopause; Methotrexate; Middle Aged; Prognosis; Random Allocation; Tamoxifen; Vincristine | 1985 |
The effects of multiple combination chemotherapy with vincristine, cyclophosphamide (Endoxan), methotrexate, 5-fluorouracil, adriamycin and prednisolone (VEMFAH) for advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisolone; Vincristine | 1985 |
The antiemetic efficacy of methylprednisolone compared with metoclopramide in outpatients receiving adjuvant CMF chemotherapy for breast cancer: a randomized trial.
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Metoclopramide; Middle Aged; Random Allocation | 1985 |
Eight-year follow-up of adjuvant therapy for stage II breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Neoplasm Staging; Prospective Studies; Random Allocation; Tamoxifen | 1985 |
Chemotherapy with or without tamoxifen in postmenopausal patients with late breast cancer. A randomized study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Menopause; Methotrexate; Prospective Studies; Random Allocation; Tamoxifen; Time Factors; Vincristine | 1985 |
Hormono-chemotherapy in the treatment of advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Hormones; Humans; Menopause; Methotrexate; Middle Aged; Prednisone; Random Allocation; Vincristine | 1985 |
Combined cytotoxic and endocrine therapy in postmenopausal patients with advanced breast cancer. A randomized EORTC study of CMF vs CMF + tamoxifen.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Random Allocation; Tamoxifen; Time Factors | 1985 |
Adjuvant endocrine therapy, cytotoxic chemotherapy and immunotherapy in stage II breast cancer: 6-year result.
Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Immunotherapy; Mastectomy; Menopause; Methotrexate; Random Allocation; Receptors, Estrogen; Tamoxifen; Time Factors | 1985 |
Adjuvant therapy for breast cancer with positive axillary nodes designed according to estrogen receptor status.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Nodes; Mastectomy; Methotrexate; Ovariectomy; Prednisone; Random Allocation; Receptors, Estrogen; Tamoxifen; Vincristine | 1985 |
Adjuvant treatment in operable breast cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Menopause; Methotrexate; Middle Aged; Patient Compliance; Prednisone; Random Allocation; Receptors, Estrogen; Tamoxifen | 1985 |
Adjuvant tamoxifen treatment in postmenopausal patients with operable breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Menopause; Methotrexate; Prognosis; Random Allocation; Tamoxifen | 1985 |
Neoadjuvant-preoperative-chemotherapy for breast cancer--preliminary report of the Vancouver trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Flow Cytometry; Fluorouracil; Humans; Methotrexate; Middle Aged; Random Allocation | 1985 |
A randomized comparison of cyclophosphamide, Adriamycin, and 5-fluorouracil with triethylenethiophosphoramide and methotrexate, both as sequential and as fixed rotational treatment in patients with advanced ovarian cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Ovarian Neoplasms; Prospective Studies; Random Allocation; Thiotepa | 1985 |
Breast cancer chemotherapy: perioperative considerations in breast reconstruction.
Topics: Adult; Alkylating Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Mastectomy; Melphalan; Methotrexate; Middle Aged; Prednisone; Surgery, Plastic; Tamoxifen; Thiotepa; Vincristine | 1985 |
Viral infection during chemotherapy for breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Virus Diseases | 1985 |
The case for combination chemotherapy in the treatment of advanced ovarian cancer.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms | 1985 |
Systemic adjuvant therapy and breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cost-Benefit Analysis; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Prednisone; Prognosis; Tamoxifen; Vincristine | 1985 |
[Results of the Hamburg ovarian blastoma study].
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Germany, West; Humans; Ifosfamide; Melphalan; Methotrexate; Neoplasm Staging; Ovarian Neoplasms; Prognosis; Random Allocation; Tegafur; Vincristine | 1985 |
[Indications and results of cytostatic therapy in gastrointestinal tumors].
Topics: Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Evaluation Studies as Topic; Fluorouracil; Gastrointestinal Neoplasms; Humans; Methotrexate; Middle Aged; Remission, Spontaneous; Vincristine | 1973 |
[Polychemotherapy of malignant neoplasms].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasms; Procarbazine; Vinblastine | 1972 |
[Control studies on the cytostatic combination therapy in metastasizing breast carcinoma].
Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Remission, Spontaneous; Time Factors; Vincristine | 1973 |
Combined radiotherapy and chemotherapy for treatment of unresectable and or metastatic cancer.
Topics: Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms; Phosphorus Radioisotopes; Remission, Spontaneous; Vincristine | 1974 |
Combination chemotherapy in disseminated solid tumours.
Topics: Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluorouracil; Humans; Kidney; Leukocyte Count; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms; Vincristine | 1974 |
Intra-arterial chemotherapy in the treatment of primary liver cancer.
Topics: Arteries; Clinical Trials as Topic; Fluorouracil; Humans; Infusions, Parenteral; Liver Neoplasms; Male; Methotrexate; Placebos | 1974 |
[Intermittent cytostatic intensive therapy of solid tumors with a combination of four drugs].
Topics: Adult; Aged; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunity, Cellular; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Neoplasms; Remission, Spontaneous; Vinblastine | 1973 |
Sequential analysis of constant and prolonged regional chemotherapy for cancer of the lung.
Topics: Aged; Carcinoma, Squamous Cell; Catheterization; Clinical Trials as Topic; Decision Making; Female; Fluorouracil; Humans; Injections, Intravenous; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Statistics as Topic; Time Factors | 1969 |
Combination chemotherapy for 418 cases of advanced cancer.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Synergism; Female; Fluorouracil; History, 16th Century; Humans; Hydrazines; Injections, Intravenous; Laryngeal Neoplasms; Male; Mechlorethamine; Mercaptopurine; Methotrexate; Neoplasm Metastasis; Neoplasms; Prognosis; Time Factors; Tongue Neoplasms; Vinblastine | 1971 |
Combined radiotherapy and chemotherapy of lymphomas and other cancers.
Topics: Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Fluorouracil; Follow-Up Studies; Hematopoietic System; Hodgkin Disease; Humans; Hydroxyurea; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Placebos; Vincristine | 1971 |
Remission induction in childhood leukemia with second course vincristine (NSC-67574) and prednisone (NSC-10023) therapy.
Topics: Adolescent; Antibiotics, Antineoplastic; Child; Child, Preschool; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Drug Combinations; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisone; Remission, Spontaneous; Vincristine | 1970 |
Long-term chemotherapy for cancer of the lung.
Topics: Aged; Carcinoma, Squamous Cell; Catheterization; Clinical Trials as Topic; Fluorouracil; Humans; Injections, Intravenous; Long-Term Care; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum | 1968 |
Comparison of antimetabolites in the treatment of breast and colon cancer.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antimetabolites; Breast Neoplasms; Child; Clinical Trials as Topic; Colonic Neoplasms; Female; Fluorouracil; Humans; Longevity; Methotrexate; Middle Aged; Rectal Neoplasms; Riboflavin | 1967 |
Chemotherapy strategies in squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Random Allocation; Sex Factors; Time Factors | 1984 |
A brief overview of findings from NSABP trials of adjuvant therapy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Humans; Mastectomy; Melphalan; Methotrexate; Prognosis; Tamoxifen | 1984 |
Toxic effects of early adjuvant chemotherapy for breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leucovorin; Methotrexate; Middle Aged; Nitrous Oxide; Postoperative Care; Random Allocation; Time Factors | 1983 |
Randomised trial of chemo-endocrine therapy, endocrine therapy, and mastectomy alone in postmenopausal patients with operable breast cancer and axillary node metastasis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Middle Aged; Prednisone; Random Allocation; Tamoxifen | 1984 |
Controlled trial of adjuvant chemotherapy with cyclophosphamide, methotrexate, and fluorouracil for breast cancer.
Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Receptors, Estrogen; Receptors, Progesterone | 1984 |
Randomised trial comparing two combination chemotherapy regimens (Hexa-CAF vs CHAP-5) in advanced ovarian carcinoma.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms; Paresthesia; Prognosis; Random Allocation; Reoperation; Time Factors | 1984 |
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Mechlorethamine; Mercaptopurine; Methotrexate; Procarbazine; Vinblastine | 1980 |
Polychemotherapy in squamous cell carcinoma of the buccal mucosa.
Topics: Adult; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cheek; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mouth Neoplasms | 1983 |
[Chemotherapy of the non-small cell bronchogenic carcinoma].
Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Vincristine | 1983 |
Chemotherapy of breast cancer. A general overview.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Hormones; Humans; Italy; Mastectomy; Methotrexate; Neoplasm Metastasis; Palliative Care; Probability | 1983 |
Integration of safe initial combination chemotherapy (without cisplatin) with a high response rate and local therapy for untreated stage III and IV epidermoid cancer of the head and neck: 5-year survival data.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydrocortisone; Leucovorin; Male; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Vincristine | 1983 |
Chemotherapy for advanced hepatocellular carcinoma. Adriamycin versus quadruple chemotherapy.
Topics: Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Prospective Studies; Random Allocation; Vincristine | 1984 |
Clinical application of the concept of methotrexate plus 5-FU sequence-dependent "synergy": how good is the evidence?
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; DNA; Drug Synergism; Fluorouracil; Humans; Immunosuppression Therapy; Mammary Neoplasms, Experimental; Methotrexate; Mice; Neoplasms; Phosphoribosyl Pyrophosphate; Rats; RNA; Sarcoma 180; Thymidylate Synthase | 1984 |
Activity of sequential low-dose methotrexate and fluorouracil in advanced colorectal carcinoma: attempt at correlation with tissue and blood levels of phosphoribosylpyrophosphate.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Diarrhea; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leucovorin; Leukopenia; Lymphocytes; Male; Methotrexate; Middle Aged; Mucous Membrane; Nausea; Pentosephosphates; Phosphoribosyl Pyrophosphate; Phosphotransferases; Prospective Studies; Rectal Neoplasms; Ribose-Phosphate Pyrophosphokinase; Thrombocytopenia; Vomiting | 1984 |
Newer techniques in cancer chemotherapy.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bleomycin; Bone Marrow Transplantation; Carcinoma; Cells, Cultured; Child; Cisplatin; Clinical Trials as Topic; Colonic Neoplasms; Combined Modality Therapy; Cytarabine; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Hepatic Artery; Humans; Hyperthermia, Induced; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Mechlorethamine; Melanoma; Meningeal Neoplasms; Methotrexate; Neoplasms; Osteosarcoma; Peritoneal Cavity; Pleura | 1984 |
[Calcitonin in bone-metastasizing breast carcinoma. Results of a pilot study].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Calcitonin; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Methotrexate; Middle Aged; Pain, Intractable; Palliative Care; Pilot Projects | 1984 |
Chemotherapy of hormonally unresponsive prostatic carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carmustine; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Diethylstilbestrol; Doxorubicin; Estramustine; Fluorouracil; Humans; Imidazoles; Lomustine; Male; Methotrexate; Mitomycin; Mitomycins; Prednimustine; Prednisone; Procarbazine; Prostatic Neoplasms; Random Allocation; Streptozocin; Vincristine | 1984 |
Adjuvant radiation therapy compared with cyclic chemotherapy in patients with mammary carcinoma. I. Changes of blood lymphocyte subpopulations.
Topics: Adult; Aged; Breast Neoplasms; Chlorambucil; Cobalt Radioisotopes; Female; Fluorouracil; Humans; Leukocyte Count; Lymphocytes; Mastectomy; Methotrexate; Middle Aged; Postoperative Care; Radiotherapy, High-Energy; Rosette Formation | 1981 |
Advanced ovarian carcinoma: a prospective and randomized clinical trial of cyclophosphamide versus combination cytotoxic chemotherapy (Hexa-CAF).
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Altretamine; Antineoplastic Agents; Carcinoma; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms; Prognosis; Prospective Studies | 1981 |
Combination chemotherapy, radiotherapy, and BCG immunotherapy in limited small-cell carcinoma of the lung: a Southwest Oncology Group Study.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Follow-Up Studies; Humans; Immunotherapy; Lung Neoplasms; Methotrexate; Mycobacterium bovis; Radiotherapy Dosage; Vincristine | 1982 |
[Management of advanced breast cancer in post-menopausal women. A comparative trial of hormonal therapy, chemotherapy, and a combination of both].
Topics: Androstanols; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Menopause; Methotrexate; Middle Aged; Random Allocation; Receptors, Estrogen; Tamoxifen | 1982 |
Influence of adjuvant chemotherapy on the blood lymphocyte population in operable breast carcinoma. Comparison between two types of treatments.
Topics: Adult; Aged; Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukocyte Count; Lymphocyte Activation; Lymphocytes; Mastectomy; Methotrexate; Middle Aged; Platelet Count; Random Allocation; Tamoxifen | 1982 |
Combined irradiation and three-drug chemotherapy in inoperable colorectal carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms; Sigmoid Neoplasms | 1982 |
A randomized attempt to increase the efficacy of cytotoxic chemotherapy in metastatic breast cancer by hormonal synchronization.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Estrogens, Conjugated (USP); Female; Fluorouracil; Humans; Methotrexate; Tamoxifen | 1984 |
Chemotherapy versus combination of chemotherapy and endocrine therapy in advanced breast cancer. A prospective randomized study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Prospective Studies; Random Allocation; Tamoxifen | 1983 |
Pre- and postoperative chemoendocrine treatment with or without postoperative radiotherapy for locally advanced breast cancer.
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymph Nodes; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Random Allocation; Vincristine | 1983 |
Prospective evaluation of rotating chemotherapy in advanced breast cancer. An Eastern Cooperative Oncology Group Trial.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Prednisone; Prospective Studies; Time Factors; Vincristine | 1983 |
Chemotherapy of breast cancer: current views and results.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Prognosis; Receptors, Estrogen; Research Design | 1983 |
Treatment of locoregionally advanced breast cancer with surgery, radiotherapy, and combination chemoimmunotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged | 1983 |
The methodologic dilemma in retrospectively correlating the amount of chemotherapy received in adjuvant therapy protocols with disease-free survival.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mathematics; Methotrexate; Middle Aged; Prognosis; Regression Analysis; Retrospective Studies; Time Factors | 1983 |
Methotrexate and 5-fluorouracil in sequence in squamous head and neck cancer.
Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Diseases; Head and Neck Neoplasms; Hematologic Diseases; Humans; Methotrexate | 1983 |
Adjuvant chemotherapy with cyclophosphamide or CMF in premenopausal women with stage II breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymph Node Excision; Mastectomy; Menopause; Methotrexate; Middle Aged; Postoperative Period; Prospective Studies; Random Allocation | 1983 |
Clinical trials and drug toxicity in the elderly. The experience of the Eastern Cooperative Oncology Group.
Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Fluorouracil; Hematologic Diseases; Humans; Methotrexate; Middle Aged; Neoplasms; Prognosis; Semustine | 1983 |
Vincristine, doxorubicin and mitomycin (VAM) in patients with advanced breast cancer previously treated with cyclophosphamide, methotrexate and fluorouracil (CMF). A clinical trial of the Piedmont Oncology Association (POA).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitomycins; Vincristine | 1983 |
Adjuvant CMF in breast cancer: comparative 5-year results of 12 versus 6 cycles.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Menstruation; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Multiple Primary; Prospective Studies; Random Allocation; Receptors, Estrogen | 1983 |
Prospective randomized trial of one-hour sequential versus simultaneous methotrexate plus 5-fluorouracil in advanced and recurrent squamous cell head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Diarrhea; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Diseases; Neoplasm Recurrence, Local; Random Allocation | 1983 |
A randomized trial of five and three drug chemotherapy and chemoimmunotherapy in women with operable node positive breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; BCG Vaccine; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Nausea; Paresthesia; Prednisone; Random Allocation; Time Factors; Vincristine; Vomiting | 1983 |
Adjuvant chemotherapy in stage-II breast cancer: an overview of the NSABP clinical trials.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Methotrexate; Middle Aged | 1983 |
Adjuvant therapy of breast cancer: the Southwest Oncology Group experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Menopause; Methotrexate; Prednisone; Vincristine | 1983 |
Multiple trials of adjuvant chemohormonal therapy in the treatment of breast cancer: preliminary results--the ECOG experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Menopause; Methotrexate; Prednisone; Tamoxifen | 1983 |
Cancer and Leukemia Group B adjuvant chemotherapy trials in postmastectomy breast cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Prednisone; Vincristine | 1983 |
Postmastectomy adjuvant chemotherapy with or without radiation therapy in women with operable breast cancer and positive axillary lymph nodes: the Southeastern Cancer Study Group experience.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate | 1983 |
Adjuvant endocrine therapy, cytotoxic chemotherapy, and immunotherapy in stage-II breast cancer: five-year results.
Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Prospective Studies; Receptors, Estrogen; Tamoxifen | 1983 |
Combination chemotherapy (VAC/FMC) with immunostimulation in metastatic breast cancer: a randomized study comparing different times and routes of administration of Corynebacterium parvum.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Humans; Immunotherapy; Injections, Intravenous; Injections, Subcutaneous; Mastectomy; Methotrexate; Prognosis; Propionibacterium acnes; Vaccines; Vincristine | 1984 |
Systemic therapy for superficial bladder cancer.
Topics: Animals; Antineoplastic Agents; Carcinoma in Situ; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; FANFT; Female; Fluorouracil; Humans; Male; Methotrexate; Mice; Neoplasm Recurrence, Local; Pyridoxine; Urinary Bladder Neoplasms; Vitamin A | 1984 |
High-dose versus low-dose CMFP regimen in advanced breast cancer.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Injections, Intravenous; Methotrexate; Prednisone; Random Allocation | 1984 |
Randomized trial of cyclophosphamide, doxorubicin, and 5-fluorouracil alone or alternating with a "cycle active" non-cross-resistant combination in women with visceral metastatic breast cancer: a Southeastern Cancer Study Group project.
Topics: Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Resistance; Female; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Methotrexate; Nausea; Random Allocation; Thrombocytopenia; Vincristine; Vomiting | 1984 |
New adjuvant trials for resectable breast cancer at the Istituto Nazionale Tumori of Milan.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Receptors, Estrogen | 1984 |
Currently active protocols in the EORTC Breast Cancer Cooperative Group.
Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Receptors, Estrogen; Tamoxifen | 1984 |
A comparison of intermittent vs. continuous and of adriamycin vs. methotrexate 5-drug chemotherapy for advanced breast cancer. A Cancer and Leukemia Group B study.
Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Heart Diseases; Humans; Leukopenia; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Random Allocation; Time Factors; Vincristine | 1984 |
Combination therapy with methotrexate and 5-fluorouracil: a prospective randomized clinical trial of order of administration.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasms; Prognosis; Random Allocation; Rectal Neoplasms; Stomach Neoplasms | 1984 |
CAP (cyclophosphamide, adriamycin, platinum) vs CMFVP (cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, prednisolone) combination chemotherapy in untreated metastatic breast cancer. A preliminary report of a controlled clinical study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Vincristine | 1984 |
[Cooperative trials of the Council of Mutual Economic Aid countries on chemoradiotherapy of lung cancer].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Czechoslovakia; Female; Fluorouracil; Humans; Hungary; Lung Neoplasms; Male; Methotrexate; Middle Aged; Multi-Institutional Systems; Random Allocation; USSR | 1984 |
Complications following postoperative combined radiation and chemotherapy in adenocarcinoma of the rectum and rectosigmoid. A randomized trial that failed.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Radiotherapy; Rectal Neoplasms; Sigmoid Neoplasms | 1984 |
Adjuvant systemic therapy in primary breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Castration; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Fluorouracil; Humans; Mastectomy; Melphalan; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Random Allocation; Receptors, Estrogen; Tamoxifen; Time Factors | 1984 |
Breast cancer 1984: state of the art.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Metastasis; Prednisone; Vincristine | 1984 |
[Metastatic breast cancer: controlled trial of chemotherapy with and without hormones].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Norethindrone; Tamoxifen; Teniposide; Vincristine | 1984 |
Ludwig Breast Cancer trial LBCS III: chemo- and endocrine adjuvant treatment in postmenopausal patients.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Middle Aged; Prednisone; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1984 |
Postmenopausal node-positive comparison of observation with CMFP and CMPF + tamoxifen adjuvant therapy: an Eastern Cooperative Oncology Group trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Prednisone; Prognosis; Tamoxifen | 1984 |
Adjuvant systemic therapy in high-risk breast cancer: the Danish Breast Cancer Cooperative Group's trials of cyclophosphamide or CMF in premenopausal and tamoxifen in postmenopausal patients.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Radiotherapy Dosage; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1984 |
Current results of the University of Arizona Adjuvant Breast Cancer trials (1974-1984).
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Fluorouracil; Humans; Lymphatic Metastasis; Male; Mastectomy; Methotrexate; Mitomycins; Neoplasm Staging; Prognosis; Vinblastine; Vincristine | 1984 |
The use of a natural history data base to compare outcome among several trials of adjuvant chemotherapy for stage II breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Methotrexate; Neoplasm Staging; Prednisone; Prognosis; Vincristine | 1984 |
Adjuvant systemic therapy in postoperative node-positive patients with breast carcinoma: the CALGB trial and the ECOG premenopausal trial.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Prednisone; Prognosis; Tamoxifen; Vincristine | 1984 |
Adjuvant therapy of breast cancer: a Southwest Oncology Group experience.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Menopause; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Prognosis; Vincristine | 1984 |
Short- or long-term chemotherapy for node-positive breast cancer: LMF 6 versus 18 cycles. SAKK study 27/76.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis | 1984 |
Adjuvant programs for postmenopausal women with node-positive breast cancer: preliminary analysis of 5-year results.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Middle Aged; Prednisone; Prognosis; Tamoxifen; Vincristine | 1984 |
Review: experience of randomized trials without surgical controls.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Prednisone; Prognosis; Tamoxifen; Vincristine | 1984 |
Tamoxifen and combination chemotherapy as adjuvant treatment in postmenopausal women with breast cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Middle Aged; Prognosis; Radiotherapy Dosage; Receptors, Estrogen; Tamoxifen | 1984 |
Scandinavian trials with a short postoperative course versus a 12-cycle course.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Prognosis; Scandinavian and Nordic Countries; Vincristine | 1984 |
A controlled trial of adjuvant chemotherapy with melphalan versus cyclophosphamide, methotrexate, and fluorouracil for breast cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis | 1984 |
A new six-drug antiblastic regimen (R 14) at low doses (micropolychemotherapy) compared to CMF in the treatment of metastatic breast cancer: phase III study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Vinblastine; Vincristine | 1984 |
Adjuvant chemotherapy for early breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasm Metastasis; Time Factors | 1983 |
Combination chemotherapy and immune capacity in advanced ovarian carcinoma.
Topics: Adult; Aged; Altretamine; Antibody Formation; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Cytotoxicity, Immunologic; Doxorubicin; Female; Fluorouracil; Humans; Immunity, Cellular; Leukocyte Count; Lymphocyte Activation; Methotrexate; Middle Aged; Ovarian Neoplasms | 1984 |
[Breast cancer: chemotherapy preceding locoregional treatment with extension of the indications for conservative treatment].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Tamoxifen; Thiotepa; Vinblastine | 1984 |
[Treatment of breast cancer at the 1st Gynecology Clinic at the University of Vienna].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Postoperative Care; Radiotherapy Dosage; Tamoxifen | 1984 |
Chemotherapy drug dose alteration due to radiation therapy in an adjuvant situation in breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Middle Aged | 1984 |
Problems in evaluating response of primary breast cancer to systemic therapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Mammography; Methotrexate; Middle Aged; Physical Examination; Tamoxifen | 1984 |
Southeastern Cancer Study Group: breast cancer studies 1972-1982.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Postoperative Care; Prednisone; Time Factors; United States; Vincristine | 1983 |
Randomized trial of 3 different regimens of combination chemotherapy in patients receiving simultaneously a hormonal treatment for advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Castration; Chlorambucil; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Prednisone; Random Allocation; Tamoxifen; Vincristine | 1983 |
A comparison of cyclophosphamide, adriamycin, and 5-fluorouracil (CAF) and cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, and prednisone (CMFVP) in patients with advanced breast cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Prednisone; Vincristine | 1983 |
Vincristine, doxorubicin, and cyclophosphamide versus low-dose intravenous cyclophosphamide, methotrexate, and 5-fluorouracil in advanced breast cancer: a randomized trial of the Piedmont Oncology Association.
Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Receptors, Estrogen; Vincristine | 1982 |
Treatment of metastatic breast cancer in estrogen receptor positive patients. A randomized trial comparing tamoxifen alone versus tamoxifen plus CMF.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Random Allocation; Receptors, Estrogen; Tamoxifen | 1982 |
Use of methotrexate and 5-FU for recurrent head and neck cancer.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Diarrhea; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infections; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neutropenia | 1982 |
Randomized clinical trial of tamoxifen plus sequential CMF chemotherapy versus tamoxifen alone in postmenopausal women with advanced breast cancer.
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Random Allocation; Receptors, Estrogen; Tamoxifen | 1981 |
[Evaluation of Picibanil as an adjuvant chemotherapeutic agent].
Topics: Adjuvants, Immunologic; Adult; Aged; Biological Products; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Picibanil; Vincristine | 1982 |
Clinical controlled trial in advanced breast cancer: CMFV (cyclophosphamide, methotrexate, fluorouracil, vincristine) verus CD (carminomycin, dibromodulcitol).
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carubicin; Clinical Trials as Topic; Cyclophosphamide; Daunorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitolactol; Vincristine | 1982 |
Multimodal treatment in operable breast cancer: five-year results of the CMF programme.
Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prospective Studies | 1981 |
Current studies of methotrexate and 5-fluorouracil and their interaction in human tumor cells.
Topics: Animals; Cells, Cultured; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Leukemia L1210; Methotrexate; Mice; Neoplasm Transplantation; Purines; Random Allocation; Thymidine | 1983 |
Therapy of advanced colorectal carcinoma with 5-fluorouracil and cyclophosphamide in combination with either CCNU or methotrexate.
Topics: Adenocarcinoma; Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lomustine; Male; Methotrexate; Middle Aged; Rectal Neoplasms; Remission, Spontaneous; Time Factors | 1980 |
Tamoxifen plus sequential CMF chemotherapy versus tamoxifen alone in postmenopausal patients with advanced breast cancer: a randomized trial.
Topics: Antineoplastic Agents; Bone Marrow; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Remission, Spontaneous; Tamoxifen | 1980 |
An overview of thymidine.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Methylthioinosine; Mice; Neoplasms; Thymidine | 1980 |
Chemoimmunotherapy for metastatic breast cancer with 5-fluorouracil, adriamycin, cyclophosphamide, methotrexate, L-asparaginase, Corynebacterium parvum, and Pseudomonas vaccine.
Topics: Alopecia; Antineoplastic Agents; Asparaginase; Bacterial Vaccines; Blood Cell Count; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Immunotherapy; Methotrexate; Nausea; Propionibacterium acnes; Pseudomonas | 1980 |
Metastatic adenocarcinomas of unknown primary site: a randomized study of two combination-chemotherapy regimens.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycins; Random Allocation | 1980 |
Adjuvant chemotherapy of breast cancer.
Topics: Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Melphalan; Menopause; Methotrexate | 1981 |
Chemotherapy in pancreatic cancer: results of a controlled, prospective, randomised, multicentre trial.
Topics: Adult; Aged; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mitomycins; Neoplasm Metastasis; Pancreatic Neoplasms; Prospective Studies; Random Allocation; Vincristine | 1980 |
Cytostatics in the treatment of chronic and acute pancreatitis.
Topics: Acute Disease; Adult; Antineoplastic Agents; Chronic Disease; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Pancreatitis; Time Factors; Vincristine | 1980 |
Advances in the multimodal primary management of cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Osteosarcoma | 1980 |
Single-drug vs combination cytotoxic chemotherapy in advanced breast cancer: a randomized study.
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Random Allocation; Vincristine | 1980 |
A new CMF regimen.
Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Injections, Intravenous; Methotrexate; Middle Aged | 1980 |
Recent progress in breast cancer management. Combined modality (adjuvant) therapy.
Topics: Adult; Animals; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Mammary Neoplasms, Experimental; Melphalan; Methotrexate; Middle Aged; Prednisone; Vincristine | 1981 |
Combination v. sequential therapy with melphalan, 5-fluorouracil and methotrexate for advanced ovarian cancer.
Topics: Adult; Aged; Antineoplastic Agents; Canada; Carcinoma; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Ovarian Neoplasms | 1980 |
Preliminary report on the efficacy of sequential methotrexate and 5-fluorouracil in advanced breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Carcinoma; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leucovorin; Methotrexate; Middle Aged | 1981 |
A randomized comparative trial of chemotherapy and irradiation therapy for stage II breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Postoperative Care; Prospective Studies; Radiotherapy Dosage; Random Allocation | 1981 |
[The results of 5 years of ancillary chemotherapy of carcinoma of the breast (author's transl)].
Topics: Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Postoperative Care; Vinblastine | 1981 |
Cyclic combination chemotherapy for metastatic breast cancer: comparison of two CMF schedules.
Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis | 1981 |
Disease-free survival at intervals during and following completion of adjuvant chemotherapy: the NSABP experience from three breast cancer protocols.
Topics: Age Factors; Aged; Breast Neoplasms; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymph Nodes; Melphalan; Methotrexate; Middle Aged; Prognosis | 1981 |
Chemotherapy of advanced breast cancer: a randomized trial of vincristine, Adriamycin, and cyclophosphamide (VAC) versus cyclophosphamide, methotrexate, 5-fluorouracil, and prednisone (CMFP).
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Random Allocation; Vincristine | 1981 |
The current status of systemic adjuvant therapy in the management of primary breast cancer.
Topics: Age Factors; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Probability; Random Allocation; Tamoxifen | 1981 |
The case for adjuvant CMF chemotherapy in breast cancer. Has it been made?
Topics: Axilla; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Menopause; Methotrexate | 1981 |
Alternating cyclical hormonal-cytotoxic combination chemotherapy in postmenopausal patients with breast cancer. An EORTC trial.
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Tamoxifen; Vincristine | 1980 |
CMF versus CMF plus tamoxifen in advanced breast cancer in postmenopausal women. An EORTC trial.
Topics: Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Random Allocation; Tamoxifen | 1980 |
Hormono-chemotherapy versus hormonotherapy followed by chemotherapy in the treatment of disseminated breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Random Allocation; Tamoxifen; Vincristine | 1980 |
Trials of adjuvant chemotherapy in breast cancer. The experience of the Istituto Nazionale Tumori of Milan.
Topics: Adult; Aged; Amenorrhea; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Random Allocation | 1980 |
Adjuvant chemotherapy with four drugs for stage 2 breast cancer.
Topics: Adenocarcinoma; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Random Allocation; Recurrence; Vincristine | 1980 |
Divergent effect of adjuvant chemo-immunotherapy on recurrence rates in node-negative and node-positive breast cancer patients.
Topics: BCG Vaccine; Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Random Allocation | 1980 |
Surgical adjuvant trials in the United States.
Topics: Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Random Allocation; Tamoxifen; Vincristine | 1980 |
Adjuvant chemotherapy, anti-estrogen therapy and immunotherapy for stage II breast cancer.
Topics: Aged; BCG Vaccine; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Random Allocation; Receptors, Estrogen; Recurrence; Tamoxifen | 1980 |
Adjuvant combination chemotherapy for operable breast cancer. Trials in progress at the Istituto Nazionale Tumori of Milan.
Topics: Aged; Amenorrhea; Axilla; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Middle Aged; Prognosis | 1981 |
[Polychemotherapy associated with oral BCG in the treatment of advanced breast carcinoma. Preliminary observations of a controlled therapeutic trial].
Topics: Antineoplastic Agents; BCG Vaccine; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate | 1981 |
Multimodal therapy with CMF in resectable breast cancer with positive axillary nodes: the Milan Institute experience.
Topics: Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Methotrexate | 1982 |
A randomized trial of postoperative five-versus three-drug chemotherapy after mastectomy: a Cancer and Leukemia Group B (CALGB) study.
Topics: Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Immunotherapy; Mastectomy; Methotrexate; Mycobacterium bovis; Prednisone; Vincristine | 1982 |
Adjuvant chemoimmunotherapy with LMF plus BCG in node-negative and node-positive breast cancer - intermediate report at 4 years.
Topics: Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Immunotherapy; Lymphatic Metastasis; Menopause; Methotrexate; Mycobacterium bovis | 1982 |
Adriamycin combinations in advanced breast cancer. A Southwest Oncology Group Study.
Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Prednisone; Random Allocation; Vincristine | 1982 |
Sequential chemotherapy of advanced colorectal cancer with standard or high-dose methotrexate followed by 5-fluorouracil.
Topics: Aged; Clinical Trials as Topic; Colonic Neoplasms; Digestive System; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Leukopenia; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Rectal Neoplasms; Uremia | 1982 |
Preliminary results of primary systemic chemotherapy in association with surgery or radiotherapy in rapidly progressing breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis | 1982 |
Occasional notes. The management of early breast cancer.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Castration; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Estrogen Antagonists; Female; Fluorouracil; Humans; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis | 1982 |
Randomized evaluation of combination chemotherapy vs. observation alone following response or stabilization after oophorectomy for metastatic breast cancer in premenopausal women.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Castration; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Random Allocation | 1982 |
Favorable factors in the adjuvant therapy of breast cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 1982 |
[Adjuvant endocrine therapy and chemotherapy of breast cancer (author's transl)].
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Castration; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Estrogen Antagonists; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Random Allocation; Tamoxifen; Vincristine | 1982 |
Combination chemotherapy (CMFVP) versus L-phenylalanine mustard (L-PAM) for operable breast cancer with positive axillary nodes: a Southwest Oncology Group Study.
Topics: Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Menopause; Methotrexate; Prednisone; Vincristine | 1982 |
[Simultaneous or sequential hormono/chemotherapy and a comparison of various polychemotherapies in the treatment of metastatic breast cancer].
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Castration; Chlorambucil; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Tamoxifen; Vincristine | 1982 |
Comparison of induction chemotherapies for metastatic breast cancer. An Eastern Cooperative Oncology Group Trial.
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukocyte Count; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Probability; Random Allocation; Time Factors; Vincristine | 1982 |
Anticipatory vomiting in women receiving cyclophosphamide, methotrexate, and 5-FU (CMF) adjuvant chemotherapy for breast carcinoma.
Topics: Activities of Daily Living; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Nausea; Patient Compliance; Random Allocation; Vomiting | 1982 |
The treatment of advanced carcinoma of the bladder with combination chemotherapy.
Topics: Antineoplastic Agents; Carcinoma, Transitional Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Middle Aged; Random Allocation; Urinary Bladder Neoplasms | 1982 |
Cyclophosphamide, methotrexate and 5-fluorouracil combination chemotherapy versus chloroethyl-cyclohexy-nitrosourea in the treatment of metastatic prostatic cancer.
Topics: Aged; Antineoplastic Agents; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Follow-Up Studies; Humans; Lomustine; Male; Methotrexate; Middle Aged; Prospective Studies; Prostatic Neoplasms; Random Allocation | 1982 |
A randomized study of combination chemotherapy (VAC-FMC) with or without immunostimulation by Corynebacterium parvum in metastatic breast cancer.
Topics: Adjuvants, Immunologic; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Propionibacterium acnes; Prospective Studies; Vincristine | 1982 |
Cyclophosphamide versus cyclophosphamide, methotrexate, and 5-fluorouracil in advanced prostatic cancer: a randomized trial.
Topics: Aged; Bone Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Prostatic Neoplasms | 1981 |
The social, emotional and financial implications of adjuvant chemotherapy in breast cancer.
Topics: Breast Neoplasms; Costs and Cost Analysis; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Mastectomy; Mental Disorders; Methotrexate | 1981 |
Significance of relapse after adjuvant treatment with combination chemotherapy or 5-fluorouracil alone in high-risk breast cancer. A Western Cancer Study Group Project.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Random Allocation | 1981 |
Antiestrogen, cytotoxic chemotherapy, and bacillus Calmette-Guerin vaccination in stage II breast cancer: a preliminary report.
Topics: Actuarial Analysis; BCG Vaccine; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prospective Studies; Receptors, Estrogen; Tamoxifen | 1980 |
Psychiatric morbidity and physical toxicity associated with adjuvant chemotherapy after mastectomy.
Topics: Affective Symptoms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Libido; Mastectomy; Melphalan; Methotrexate | 1980 |
Chemotherapy of advanced esophageal carcinoma: Eastern Cooperative Oncology Group experience.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Doxorubicin; Drug Therapy, Combination; Esophageal Neoplasms; Fluorouracil; Humans; Methotrexate; Random Allocation | 1980 |
Randomized comparison of cisplatin, methotrexate, bleomycin and vincristine (CABO) versus cisplatin and 5-fluorouracil (CF) versus cisplatin (C) in recurrent or metastatic squamous cell carcinoma of the head and neck. A phase III study of the EORTC Head a
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chi-Square Distribution; Cisplatin; Disease-Free Survival; Europe; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Proportional Hazards Models; Remission Induction; Vincristine | 1994 |
The use of G-CSF or GM-CSF mobilized peripheral blood progenitor cells (PBPC) alone or to augment marrow as hematologic support of single or multiple cycle high-dose chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Bone Marrow Transplantation; Breast Neoplasms; Carboplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Graft Survival; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Leukapheresis; Male; Melphalan; Methotrexate; Middle Aged; Neoplasms; Neutropenia; Salvage Therapy; Treatment Outcome | 1993 |
Intra-arterial chemotherapy using a reservoir for endocrine-refractory prostate cancer.
Topics: Abdominal Muscles; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Drug Implants; Fluorouracil; Humans; Iliac Artery; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prostate-Specific Antigen; Prostatic Neoplasms; Survival Rate; Thigh | 1994 |
Reduction of the systemic toxicity of cisplatin by intra-arterial hepatic route administration for liver malignancies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Kidney Diseases; Leucovorin; Liver; Liver Neoplasms; Methotrexate; Neoplasms; Nervous System Diseases; Ovarian Neoplasms; Remission Induction; Spectrophotometry, Atomic; Tumor Cells, Cultured; Vinblastine | 1995 |
Randomised comparison of fluorouracil, epidoxorubicin and methotrexate (FEMTX) plus supportive care with supportive care alone in patients with non-resectable gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Palliative Care; Stomach Neoplasms; Vitamin A; Vitamin E | 1995 |
MACOP-B vs F-MACHOP regimen in the treatment of high-grade non-Hodgkin's lymphomas.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Diseases; Cyclophosphamide; Cytarabine; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Italy; Leucovorin; Life Tables; Lymphoma, Non-Hodgkin; Male; Mediastinal Neoplasms; Methotrexate; Prednisone; Prognosis; Proportional Hazards Models; Prospective Studies; Remission Induction; Risk Factors; Treatment Outcome; Vincristine | 1995 |
Accumulation of p53 protein as a possible predictor of response to adjuvant combination chemotherapy with cyclophosphamide, methotrexate, fluorouracil, and prednisone for breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Proteins; Predictive Value of Tests; Prednisone; Proportional Hazards Models; Risk; Survival Analysis; Treatment Outcome; Tumor Suppressor Protein p53 | 1995 |
[Intra-arterial 5-FU/intra-venous MTX therapy for metastatic liver lesions].
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Gastrointestinal Neoplasms; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Remission Induction | 1995 |
[A study of chemotherapy for patients with severely advanced gastric cancer--comparison of chemotherapy and route].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Routes; Drug Administration Schedule; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Infusions, Intravenous; Methotrexate; Prognosis; Stomach Neoplasms | 1995 |
[Intraperitoneal infusion therapy of MTX and 5-FU for advanced gastric cancer and its peritoneal metastasis].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Parenteral; Lymphatic Metastasis; Methotrexate; Middle Aged; Peritoneal Neoplasms; Stomach Neoplasms | 1995 |
p53 expression and the result of adjuvant therapy of breast cancer.
Topics: Aneuploidy; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; DNA Damage; DNA, Neoplasm; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Mastectomy, Modified Radical; Methotrexate; Neoplasm Recurrence, Local; Postoperative Care; Premenopause; Risk Factors; Tumor Suppressor Protein p53 | 1995 |
Evaluation of GM-CSF mouthwash for prevention of chemotherapy-induced mucositis: a randomized, double-blind, dose-ranging study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Breast Neoplasms, Male; Dose-Response Relationship, Drug; Double-Blind Method; Doxorubicin; Evaluation Studies as Topic; Female; Fluorouracil; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Logistic Models; Male; Methotrexate; Mouth Mucosa; Mouthwashes; Risk Factors | 1995 |
Effect of timing of surgery during the menstrual cycle of premenopausal breast cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Humans; Menstrual Cycle; Methotrexate; Multivariate Analysis; Premenopause; Prognosis; Risk Factors; Survival Analysis; Time Factors; Treatment Outcome | 1995 |
Randomized cooperative study of perioperative chemotherapy in breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Italy; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Multivariate Analysis; Postmenopause; Receptors, Estrogen; Survival Rate; Tamoxifen | 1995 |
[A randomized 2 x 2 trial evaluating hormonal treatment and the duration of chemotherapy in node-positive breast cancer patients].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Randomized Controlled Trials as Topic; Tamoxifen | 1995 |
Adjuvant chemotherapy in the treatment of the breast.
Topics: Breast Neoplasms; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Retrospective Studies; Survival Rate | 1994 |
[Clinical evaluation of sequential MTX/5-FU therapy for gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; Humans; Methotrexate; Neoplasm Recurrence, Local; Prognosis; Stomach Neoplasms; Survival Rate | 1995 |
Adjuvant CMF in breast cancer, Siriraj Hospital experience.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Humans; Mastectomy; Mastectomy, Segmental; Methotrexate; Middle Aged; Retrospective Studies; Thailand | 1995 |
[A pilot study of combined chemotherapy using methotrexate (MTX), 5-fluorouracil (5-FU) and pirarubicin (THP) for advanced or recurrent gastric cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects; Stomach Neoplasms | 1995 |
Granulocyte colony-stimulating factor: effective in ameliorating fluorouracil-based myelosuppression?
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Doxorubicin; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Methotrexate; Neutrophils | 1993 |
Chemotherapeutic treatment of recurrent and/or metastatic nasopharyngeal carcinoma: a retrospective analysis of 40 cases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasm Recurrence, Local; Retrospective Studies | 1993 |
New strategies in marrow purging for breast cancer patients receiving high-dose chemotherapy with autologous bone marrow transplantation.
Topics: Amifostine; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Stem Cells | 1993 |
Design and rationale of a randomised comparison of cyclophosphamide, methotrexate and fluorouracil vs fluorouracil, epirubicin and cyclophosphamide in node-positive premenopausal women with operable breast cancer. A trial of the International Collaborativ
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Infusions, Intravenous; Lymphatic Metastasis; Methotrexate; Middle Aged; Premenopause | 1993 |
Short-course FAC-M versus 1 year of CMFVP in node-positive, hormone receptor-negative breast cancer: an intergroup study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chi-Square Distribution; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Prednisone; Proportional Hazards Models; Receptors, Estrogen; Survival Rate; United States; Vincristine | 1995 |
The pharmacologic modulation of 5-fluorouracil with folinic acid, methotrexate, trimetrexate, and n-phosphonacetyl-l-aspartic acid (PALA). Mechanisms of the interactions and clinical data.
Topics: Aspartic Acid; Drug Interactions; Fluorouracil; Humans; Leucovorin; Methotrexate; Neoplasms; Phosphonoacetic Acid; Trimetrexate | 1994 |
Changes in biological markers after primary chemotherapy for breast cancers.
Topics: Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Breast Neoplasms; Cell Cycle; Cell Division; Cyclophosphamide; Diploidy; DNA, Neoplasm; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Mitoxantrone; Neoplasm Staging; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; S Phase; Thymidine; Tumor Suppressor Protein p53 | 1995 |
Combination chemotherapy for metastatic or recurrent carcinoma of the breast--a randomized phase III trial comparing CAF versus VATH versus VATH alternating with CMFVP: Cancer and Leukemia Group B Study 8281.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Fluoxymesterone; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Regression Analysis; Thiotepa; Treatment Failure; Vinblastine; Vincristine | 1995 |
CMF vs alternating CMF/EV in the adjuvant treatment of operable breast cancer. A single centre randomised clinical trial (Naples GUN-3 study).
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Etoposide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Staging; Survival Rate; Vindesine | 1995 |
Ten-year results of a randomized trial evaluating prolonged low-dose adjuvant chemotherapy in node-positive breast cancer: a joint European Organization for Research and Treatment of Cancer-Dutch Breast Cancer Working Party Study. Cooperating Investigator
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Recurrence, Local; Prospective Studies | 1995 |
[Clinical study of ambulatory cancer chemotherapy for recurrent breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Drug Administration Schedule; Female; Fluorouracil; Home Care Services, Hospital-Based; Home Infusion Therapy; Humans; Infusions, Intravenous; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 1994 |
The International (Ludwig) Breast Cancer Study Group Trials I-IV: 15 years follow-up.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Ovariectomy; Postmenopause; Prednisone; Premenopause; Survival Rate; Switzerland; Tamoxifen | 1994 |
Alternating chemotherapy regimens for patients with metastatic breast cancer. A pilot study based on tumor marker kinetics. Cancer and Leukemia Group B.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Pilot Projects; Remission Induction; Vincristine | 1995 |
Simultaneous adjuvant radiation therapy and chemotherapy in high-risk breast cancer--toxicity and dose modification: a Transtasman Radiation Oncology Group Multi-Institution study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Australia; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Radiation Oncology; Radiotherapy; Radiotherapy Dosage; Radiotherapy, Adjuvant | 1995 |
Sequential or alternating doxorubicin and CMF regimens in breast cancer with more than three positive nodes. Ten-year results.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Prospective Studies; Regression Analysis; Survival Analysis | 1995 |
Combined chemotherapy and radiotherapy for patients with breast cancer and extensive nodal involvement.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Fluorouracil; Follow-Up Studies; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Postoperative Care; Radiotherapy Dosage; Recurrence; Retrospective Studies; Time Factors | 1995 |
Second malignancies following CMF-based adjuvant chemotherapy in resectable breast cancer.
Topics: Actuarial Analysis; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasms, Second Primary; Prospective Studies; Radiotherapy; Risk Factors | 1994 |
Adjuvant cyclophosphamide, methotrexate, and fluorouracil in node-positive breast cancer: the results of 20 years of follow-up.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Lymphatic Metastasis; Mastectomy, Radical; Methotrexate; Middle Aged; Regression Analysis; Treatment Outcome | 1995 |
Intra-arterial chemotherapy in patients with breast cancer: a feasibility study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Feasibility Studies; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Leucovorin; Methotrexate; Middle Aged; Mitomycin; Mitoxantrone; Neoplasm Staging | 1995 |
Sequential methotrexate, 5-fluorouracil (5-FU), and high dose leucovorin versus 5-FU and high dose leucovorin versus 5-FU alone for advanced colorectal cancer. A multi-institutional randomized trial.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Survival Analysis | 1995 |
Treatment of advanced mycosis fungoides and Sézary syndrome with continuous infusions of methotrexate followed by fluorouracil and leucovorin rescue.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Methotrexate; Middle Aged; Mycosis Fungoides; Neoplasm Staging; Neoplasms, Multiple Primary; Sezary Syndrome; Skin Neoplasms; Survival Rate | 1995 |
Effect of systemic adjuvant treatment on first sites of breast cancer relapse.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Incidence; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prednisone; Proportional Hazards Models; Survival Analysis; Tamoxifen; Treatment Outcome | 1994 |
Delayed chemotherapy-induced nausea is augmented by high levels of endogenous noradrenaline.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Circadian Rhythm; Cisplatin; Cohort Studies; Epinephrine; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Individuality; Lymphoma; Male; Methotrexate; Middle Aged; Nausea; Norepinephrine; Ovarian Neoplasms; Predictive Value of Tests; Time Factors; Vomiting | 1994 |
Adjuvant CMFVP versus tamoxifen versus concurrent CMFVP and tamoxifen for postmenopausal, node-positive, and estrogen receptor-positive breast cancer patients: a Southwest Oncology Group study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Postmenopause; Prednisone; Proportional Hazards Models; Receptors, Estrogen; Tamoxifen; United States; Vincristine | 1994 |
Randomized 2 x 2 trial evaluating hormonal treatment and the duration of chemotherapy in node-positive breast cancer patients. German Breast Cancer Study Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Germany; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Multivariate Analysis; Patient Compliance; Regression Analysis; Survival Rate; Tamoxifen | 1994 |
Vinorelbine is an active antiproliferative agent in pretreated advanced breast cancer patients: a phase II study.
Topics: Adult; Aged; Anemia; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Follow-Up Studies; Humans; Italy; Leukopenia; Methotrexate; Middle Aged; Remission Induction; Survival Rate; Vinblastine; Vinorelbine | 1994 |
[Use of dexamethasone as an antiemetic in patients with breast cancer treated with the CMF regimen].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Nausea; Treatment Outcome; Vomiting | 1994 |
[Methotrexate/5-fluorouracil therapy in gastric cancer with peritoneal metastasis].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Peritoneal Neoplasms; Prognosis; Stomach Neoplasms | 1994 |
[Intra-arterial infusion chemotherapy for recurrent breast cancer via an implantable system--the second report].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 1994 |
Dose and volume effects on fibrosis after breast conservation therapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Female; Fibrosis; Fluorouracil; Follow-Up Studies; Humans; Iridium Radioisotopes; Lymph Node Excision; Mastectomy; Methotrexate; Middle Aged; Probability; Radiation Injuries; Radiotherapy; Radiotherapy Dosage; Regression Analysis | 1994 |
[Adriamycin/cyclophosphamide: current standard in the adjuvant therapy of breast carcinoma? Or: how should one really put this question?].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiomyopathies; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged | 1994 |
Primary (neoadjuvant) chemotherapy and radiotherapy compared with primary radiotherapy alone in stage IIb-IIIa breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Chi-Square Distribution; Combined Modality Therapy; Disease-Free Survival; Fluorouracil; Humans; Mastectomy, Modified Radical; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Remission Induction; Thiotepa | 1994 |
Sixteen week dose intense chemotherapy for inoperable, locally advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Methotrexate; Middle Aged; Remission Induction; Vincristine | 1993 |
[Randomized controlled study of sequential methotrexate and 5-fluorouracil therapy with or without 5'-deoxy-5-fluorouridine against advanced gastrointestinal cancer. Hirosaki Cooperative Study Group for Cancer Chemotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Quality of Life; Survival Analysis | 1994 |
[The value of the "vascular invasion" factor for prognosis of breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Muscle, Smooth, Vascular; Neoplasm Staging; Neoplastic Cells, Circulating; Prognosis; Prospective Studies; Receptors, Estrogen; Receptors, Progesterone; Survival Rate | 1994 |
Sequential treatment with high-dose methotrexate and fluorouracil in advanced colorectal cancer. Experience of the Southern Italian Oncology Group (GOIM).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Italy; Male; Methotrexate; Middle Aged | 1994 |
Patterns of failure of complete responders following high-dose chemotherapy and autologous bone marrow transplantation for metastatic breast cancer: implications for the use of adjuvant radiation therapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Metastasis; Treatment Failure; Vincristine | 1994 |
[Clinical evaluation of cyclophosphamide, methotrexate and 5-fluorouracil (CMF) on advanced and recurrent breast cancer. Clinical study group of CMF for breast cancer in Japan].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 1994 |
Adjuvant ovarian ablation versus CMF chemotherapy in premenopausal women with pathological stage II breast carcinoma: the Scottish trial. Scottish Cancer Trials Breast Group and ICRF Breast Unit, Guy's Hospital, London.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovariectomy; Ovary; Prednisolone; Receptors, Estrogen; Survival Rate | 1993 |
Premenopausal oopherectomy versus CMF chemotherapy in stage II breast carcinoma. The International Breast Cancer Study Group (IBCSG)
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Ovariectomy; Prednisolone | 1993 |
Randomized trial of cyclophosphamide, methotrexate, and 5-fluorouracil with or without estrogenic recruitment in women with metastatic breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Diethylstilbestrol; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Receptors, Estrogen; Remission Induction; S Phase; Survival Rate; Time Factors; Treatment Outcome | 1994 |
[Combination of 5-FU, high dose methotrexate, epirubicin and cisplatin (FEMTX-P protocol) in non surgical or locally recurrent metastatic gastric cancers].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Epirubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Stomach Neoplasms; Treatment Outcome | 1993 |
Epirubicin-sequential methotrexate-5-fluorouracil-leucovorin treatment in advanced cancer of the extrahepatic biliary system. A phase II study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Extrahepatic; Biliary Tract Neoplasms; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Survival Analysis | 1994 |
[Sequential methotrexate/5-fluorouracil therapy with 5'-deoxy-5-fluorouridine against advanced gastric cancer: comparison between bolus injection and drip infusion of 5-fluorouracil administration. Hirosaki Cooperative Study Group for Cancer Chemotherapy]
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Alopecia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Humans; Infusions, Intravenous; Injections, Intravenous; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Stomach Neoplasms | 1994 |
The influence of adjuvant chemotherapy on outcome after relapse for patients with breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Tamoxifen; Time Factors; Treatment Outcome | 1993 |
Short-term administration of granulocyte-macrophage colony stimulating factor decreases hematopoietic toxicity of cytostatic drugs.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Humans; Methotrexate; Middle Aged; Neutropenia; Thrombocytopenia | 1993 |
Carboplatin in combination as first-line therapy in advanced breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neutropenia; Thrombocytopenia | 1993 |
[Combination therapy with low dose adriamycin for advanced or recurrent breast cancer. Hokkaido Breast Cancer Treatment Study Group].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Picibanil; Survival Rate; Tamoxifen; Treatment Outcome | 1993 |
[Comparison of the therapeutic effect of CMxMF and CAMF regimens in the management of advanced breast cancer patients].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Carcinoma, Ductal, Breast; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitoxantrone | 1993 |
[High dose cisplatin combination chemotherapy for advanced breast cancer--a report on 50 cases].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cisplatin; Cyclophosphamide; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nausea; Soft Tissue Neoplasms | 1993 |
Conservative surgery in breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Feasibility Studies; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Node Excision; Mastectomy, Radical; Methotrexate; Pilot Projects; Radiotherapy Dosage; Survival Analysis | 1993 |
Endocrine factors in the outcome of systemic adjuvant therapy of early breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Ovariectomy; Postmenopause; Premenopause; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Survival Rate; Tamoxifen; Treatment Outcome | 1993 |
The EBCTCG overview of adjuvant therapy of breast cancer. What are the implications for future studies? Early Breast Cancer Trialists' Collaborative Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovariectomy; Postmenopause; Premenopause; Retrospective Studies; Tamoxifen | 1993 |
Double modulation of 5-fluorouracil in the treatment of advanced colorectal carcinoma: report of a trial with sequential methotrexate, intravenous (loading dose) folinic acid, 5-fluorouracil, and a literature review.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colorectal Neoplasms; Diarrhea; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome | 1994 |
Quality of life during chemotherapy in patients with symptomatic advanced colorectal cancer. The Nordic Gastrointestinal Tumor Adjuvant Therapy Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Quality of Life; Surveys and Questionnaires | 1994 |
Continuous chemotherapy in responsive metastatic breast cancer: a role for tumour markers?
Topics: Adult; Aged; Antigens, Tumor-Associated, Carbohydrate; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blood Sedimentation; Breast Neoplasms; Carcinoembryonic Antigen; Cyclophosphamide; Drug Administration Schedule; Drug Monitoring; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Reagent Kits, Diagnostic; Receptors, Estrogen; Time Factors | 1993 |
Ten-year results utilizing chemotherapy as primary treatment in nonmetastatic, rapidly progressing breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Remission Induction; Survival Analysis | 1993 |
Phase II study of sequential high-dose methotrexate (MTX) and 5-fluorouracil (F) alternated with epirubicin (E) and cisplatin (P) [FEMTX-P] in advanced gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Epirubicin; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Stomach Neoplasms; Thrombocytopenia | 1993 |
Oral ondansetron in the prophylaxis of nausea and vomiting induced by cyclophosphamide, methotrexate and 5-fluorouracil (CMF) in women with breast cancer. Results of a prospective, randomized, double-blind, placebo-controlled study.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Double-Blind Method; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Nausea; Ondansetron; Prospective Studies; Vomiting | 1993 |
One versus 2 years of CMFVP adjuvant chemotherapy in axillary node-positive and estrogen receptor-negative patients: a Southwest Oncology Group study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Prednisone; Proportional Hazards Models; Receptors, Estrogen; Survival Analysis; Time Factors; Vincristine | 1993 |
Primary medical (neo-adjuvant) chemotherapy for operable breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitomycin; Mitoxantrone | 1993 |
An intensive sequenced adjuvant chemotherapy regimen for breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Feasibility Studies; Female; Fluorouracil; Follow-Up Studies; Humans; Menopause; Methotrexate; Middle Aged; Prednisone; Vincristine | 1993 |
High-dose carboplatin and mitoxantrone with autologous bone marrow support in the treatment of advanced breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Carboplatin; Chemotherapy, Adjuvant; Cyclophosphamide; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Staging; Survival Analysis; Transplantation, Autologous | 1993 |
A daily diary for quality of life measurement in advanced breast cancer trials.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Patient Compliance; Quality of Life | 1993 |
Adjuvant randomized trials of doxorubicin/cyclophosphamide versus doxorubicin/cyclophosphamide/tamoxifen and CMF chemotherapy versus tamoxifen in women with node-positive breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Prospective Studies; Tamoxifen | 1993 |
Ondansetron compared with dexamethasone and metoclopramide as antiemetics in the chemotherapy of breast cancer with cyclophosphamide, methotrexate, and fluorouracil.
Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Metoclopramide; Middle Aged; Nausea; Ondansetron; Regression Analysis; Vomiting | 1993 |
Chemotherapy and survival in advanced breast cancer: the inclusion of doxorubicin in Cooper type regimens.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Meta-Analysis as Topic; Methotrexate; Prednisone; Proportional Hazards Models; Vincristine | 1993 |
Biochemical modulation of 5-fluorouracil: a randomized comparison of sequential methotrexate, 5-fluorouracil and leucovorin versus sequential 5-fluorouracil and leucovorin in patients with advanced symptomatic colorectal cancer. The Nordic Gastrointestina
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Survival Rate | 1993 |
MMM (mitomycin/mitoxantrone/methotrexate): an effective new regimen in the treatment of metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Humans; Melphalan; Menopause; Methotrexate; Middle Aged; Mitomycin; Neoplasm Metastasis; Neoplasm Staging; Vincristine | 1993 |
Comparison of adjuvant chemotherapy with methotrexate and fluorouracil with and without cyclophosphamide in breast cancer patients with one to three positive axillary lymph nodes.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Proportional Hazards Models | 1993 |
A preliminary report of a pilot randomized trial comparing cyclophosphamide, methotrexate and 5-fluorouracil with cyclophosphamide, mitoxantrone and 5-fluorouracil in the adjuvant therapy of stage II breast cancer with four or more positive axillary nodes
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukocyte Count; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Mitoxantrone; Pilot Projects; Prospective Studies | 1993 |
Primary chemotherapy for resectable breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitoxantrone | 1993 |
Maintenance tamoxifen after induction postoperative chemotherapy in node-positive breast cancer patients: the Eastern Cooperative Oncology Group Trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Fluoxymesterone; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Neoplasm Recurrence, Local; Prednisone; Receptors, Estrogen; Survival Rate; Tamoxifen; Thiotepa; Vinblastine | 1993 |
Cyclophosphamide, methotrexate, and 5-fluorouracil in the treatment of metastatic prostate cancer. A Southwest Oncology Group study.
Topics: Acid Phosphatase; Adenocarcinoma; Aged; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Prostatic Neoplasms; Remission Induction; Survival Rate | 1993 |
Modified therapy with 5-fluorouracil, doxorubicin, and methotrexate in advanced gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Stomach Neoplasms | 1993 |
Prednimustine (Sterecyt) versus cyclophosphamide both in combination with methotrexate and 5-fluorouracil in the treatment of advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednimustine; Prognosis; Treatment Failure | 1993 |
[Possible effect of administration methods on pharmacological action. Study of cytostatic therapy in advanced cancer].
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged; Rectal Neoplasms; Retrospective Studies | 1995 |
[Simultaneous radiochemotherapy in recurrent and metastatic breast neoplasm. Clinical experience].
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Mitomycin; Neoplasm Recurrence, Local; Radiotherapy Dosage; Radiotherapy, Adjuvant; Treatment Outcome | 1995 |
Adjuvant six cycles of high-dose adriamycin, cyclophosphamide, methotrexate, 5-fluorouracil (ACMF) vs. 12 cycles of low-dose ACMF with tamoxifen for premenopausal, node-positive breast cancer patients: results of a prospective randomized study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Prospective Studies; Survival Rate; Tamoxifen | 1995 |
Induction chemotherapy with cisplatin, doxorubicin, and cyclophosphamide (CAP) in a combined modality approach for locally advanced and inflammatory breast cancer. Long-term results.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Mastectomy, Radical; Methotrexate; Middle Aged; Neoplasm Staging; Radiotherapy Dosage | 1996 |
Adjuvant cyclophosphamide, methotrexate, and fluorouracil versus fluorouracil, epirubicin, and cyclophosphamide chemotherapy in premenopausal women with axillary node-positive operable breast cancer: results of a randomized trial. The International Collab
Topics: Adult; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Hematologic Diseases; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Nausea; Premenopause; Regression Analysis; Survival Analysis; Vomiting | 1996 |
Adjuvant CMFVP versus adjuvant CMFVP plus ovariectomy for premenopausal, node-positive, and estrogen receptor-positive breast cancer patients: a Southwest Oncology Group study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chi-Square Distribution; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Ovariectomy; Prednisone; Premenopause; Proportional Hazards Models; Receptors, Estrogen; Survival Rate; Vincristine | 1996 |
The use of mammography in breast preservation in locally advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Breast Neoplasms; Calcinosis; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Estrogens, Conjugated (USP); Female; Fluorouracil; Humans; Mammography; Mastectomy, Modified Radical; Methotrexate; Predictive Value of Tests; Prognosis; Prospective Studies; Tamoxifen | 1996 |
Improved local control and disease-free survival after perioperative chemotherapy for early-stage breast cancer. A European Organization for Research and Treatment of Cancer Breast Cancer Cooperative Group Study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Europe; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Postmenopause; Premenopause | 1996 |
Effect of adjuvant chemotherapy with or without anthracyclines on the activity and efficacy of first-line cyclophosphamide, epidoxorubicin, and fluorouracil in patients with metastatic breast cancer.
Topics: Adult; Aged; Analysis of Variance; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Diethylstilbestrol; Disease Progression; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged | 1996 |
Anaplastic large-cell lymphoma: clinical and prognostic evaluation of 90 adult patients.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Fluorouracil; Humans; Leucovorin; Lymphoma, Large-Cell, Anaplastic; Male; Methotrexate; Middle Aged; Phenotype; Prednisone; Prospective Studies; Recurrence; Survival Rate; Vincristine | 1996 |
Five-day course of granulocyte colony-stimulating factor in patients with prolonged neutropenia after adjuvant chemotherapy for breast cancer is a safe and cost-effective schedule to maintain dose-intensity.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Breast Neoplasms, Male; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Leukocyte Count; Male; Methotrexate; Middle Aged; Neutropenia; Safety | 1996 |
Postsurgical adjuvant chemotherapy of stage II breast carcinoma with or without crossover to a non-cross-resistant regimen: a Cancer and Leukemia Group B study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Fluoxymesterone; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Postoperative Period; Prednisone; Probability; Survival Analysis; Thiotepa; Vinblastine; Vincristine | 1996 |
Higher frequency of gene amplification in breast cancer patients who received adjuvant chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Gene Amplification; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Polymerase Chain Reaction; Tamoxifen; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 1996 |
A long-term assessment of adjuvant chemotherapy on outcome of patients with extracapsular spread of cervical metastases from squamous carcinoma of the head and neck.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Disease-Free Survival; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Treatment Outcome | 1996 |
High-dose chemotherapy followed by autologous bone marrow transplantation versus dexamethasone, cisplatin, and cytarabine in aggressive non-Hodgkin's lymphoma with partial response to front-line chemotherapy: a prospective randomized italian multicenter s
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplantation; Carmustine; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Etoposide; Female; Fluorouracil; Humans; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Salvage Therapy; Vincristine | 1996 |
Biochemical modulation of fluorouracil: comparison of methotrexate, folinic acid, and fluorouracil versus folinic acid and fluorouracil in advanced colorectal cancer: a randomized trial.
Topics: Adenocarcinoma; Adult; Aged; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Death; Colorectal Neoplasms; Dose-Response Relationship, Drug; Enzyme Stability; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged | 1996 |
Adjuvant treatment of node-positive breast cancer with cyclophosphamide, doxorubicin, fluorouracil, and vincristine versus cyclophosphamide, methotrexate, and fluorouracil: final report after a 16-year median follow-up duration.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; France; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Staging; Postmenopause; Premenopause; Survival Analysis; Treatment Outcome; Vincristine | 1996 |
Effects of primary chemotherapy on biological parameters of locally advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cisplatin; Cyclophosphamide; Epirubicin; Evaluation Studies as Topic; Female; Fluorouracil; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Methotrexate; Middle Aged; Prospective Studies; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptor, IGF Type 1; Thymidine; Treatment Outcome; Tritium | 1996 |
Neoadjuvant therapy of high-risk gastric cancer: a phase II trial of preoperative FAMTX and postoperative intraperitoneal fluorouracil-cisplatin plus intravenous fluorouracil.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Infusions, Intravenous; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Risk Factors; Stomach Neoplasms; Survival Rate; Ultrasonography | 1996 |
Duration and reintroduction of adjuvant chemotherapy for node-positive premenopausal breast cancer patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Premenopause; Treatment Failure | 1996 |
Multimodal biochemical modulation of 5-fluorouracil by leucovorin, methotrexate, and interferon alpha in patients with advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Feasibility Studies; Female; Fluorouracil; Humans; Interferon alpha-2; Interferon-alpha; Leucovorin; Male; Methotrexate; Middle Aged; Pilot Projects; Recombinant Proteins; Remission Induction | 1996 |
Simultaneous radiochemotherapy for recurrent and metastatic breast carcinoma: evaluation of two treatment concepts.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Feasibility Studies; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Mitomycin; Neoplasm Recurrence, Local; Palliative Care; Prognosis; Radiotherapy; Remission Induction | 1996 |
Sequential methotrexate and fluorouracil for the treatment of node-negative breast cancer patients with estrogen receptor-negative tumors: eight-year results from National Surgical Adjuvant Breast and Bowel Project (NSABP) B-13 and first report of finding
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Receptors, Estrogen; Survival Rate | 1996 |
Timing of radiotherapy and chemotherapy following breast-conserving surgery for patients with node-positive breast cancer. International Breast Cancer Study Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Time Factors | 1996 |
Modulation of high-dose infusional fluorouracil by low-dose methotrexate in patients with advanced or metastatic colorectal cancer: final results of a randomized European Organization for Research and Treatment of Cancer Study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Europe; Female; Fluorouracil; Humans; Infusions, Intravenous; Karnofsky Performance Status; Male; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Prognosis; Proportional Hazards Models; Remission Induction; Survival Rate | 1996 |
Monitoring bulky mediastinal disease with gallium-67, CT-scan and magnetic resonance imaging in Hodgkin's disease and high-grade non-Hodgkin's lymphoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dacarbazine; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Gallium Radioisotopes; Hodgkin Disease; Humans; Leucovorin; Lymphoma, Non-Hodgkin; Magnetic Resonance Imaging; Male; Mediastinal Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm, Residual; Prednisone; Radioimmunodetection; Radiotherapy; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Treatment Outcome; Vinblastine; Vincristine | 1996 |
Primary Mediastinal B-cell lymphoma with sclerosis: clinical and therapeutic evaluation of 22 patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Evaluation Studies as Topic; Female; Fluorouracil; Gallium Radioisotopes; Humans; Leucovorin; Lymphoma, B-Cell; Male; Mediastinal Neoplasms; Methotrexate; Prednisone; Sclerosis; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Vincristine | 1996 |
The effect of adjuvant prednisone combined with CMF on patterns of relapse and occurrence of second malignancies in patients with breast cancer. International (Ludwig) Breast Cancer Study Group.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Neoplasms, Second Primary; Prednisone; Survival Rate | 1996 |
A Bayesian analysis of bivariate survival data from a multicentre cancer clinical trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Cisplatin; Colorectal Neoplasms; Dose-Response Relationship, Drug; Fluorouracil; Humans; Leucovorin; Markov Chains; Methotrexate; Monte Carlo Method; Proportional Hazards Models; Survival Analysis; Survival Rate; Treatment Outcome | 1995 |
5-fluorouracil modulates the toxicity of high dose methotrexate.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasms | 1995 |
Chemotherapy-induced emesis: management of early and delayed emesis in milder emetogenic regimens.
Topics: Administration, Oral; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Epirubicin; Female; Fluorouracil; Humans; Infusions, Intravenous; Methotrexate; Metoclopramide; Ondansetron; Patient Satisfaction; Quality of Life; Surveys and Questionnaires; Vomiting | 1996 |
A pilot study of infusional CMF (CMF-inf): active and well tolerated in breast cancer. The Edinburgh Breast Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Female; Fluorouracil; Humans; Infusions, Intravenous; Methotrexate; Middle Aged; Pilot Projects | 1996 |
Randomised controlled trial of conservation therapy for breast cancer: 6-year analysis of the Scottish trial. Scottish Cancer Trials Breast Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Incidence; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Odds Ratio; Radiotherapy, Adjuvant; Receptors, Estrogen; Survival Analysis; Survival Rate; Tamoxifen | 1996 |
Prevention of delayed emesis by a single intravenous bolus dose of 5-HT3-receptor-antagonist in moderately emetogenic chemotherapy.
Topics: Adolescent; Adult; Aged; Antiemetics; Antineoplastic Agents; Breast Neoplasms; Cisplatin; Cost-Benefit Analysis; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Granisetron; Granulocyte Colony-Stimulating Factor; Humans; Indoles; Injections, Intravenous; Methotrexate; Middle Aged; Ondansetron; Serotonin Antagonists; Tropisetron; Vomiting | 1996 |
A phase I study of methotrexate administration following 5-fluorouracil.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms; Survival Rate | 1996 |
Sequential methotrexate and 5-fluorouracil as second-line chemotherapy for advanced colorectal cancer patients pretreated with 5-fluorouracil and leucovorin: a GISCAD study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Salvage Therapy | 1996 |
Misoprostol and omeprazole in the prevention of chemotherapy-induced acute gastroduodenal mucosal injury. A randomized, placebo-controlled pilot study.
Topics: Adult; Aged; Anti-Ulcer Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Gastric Acid; Gastric Mucosa; Humans; Male; Methotrexate; Middle Aged; Misoprostol; Omeprazole; Peptic Ulcer; Pilot Projects | 1996 |
Adjuvant cyclophosphamide, methotrexate and fluorouracil in node-negative and estrogen receptor-negative breast cancer. Updated results.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Confidence Intervals; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Italy; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Receptors, Estrogen; Survival Rate | 1996 |
[Arterial infusion chemotherapy for advanced gastric cancer by sequential MTX/5-FU].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ring Cell; Drug Administration Schedule; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Methotrexate; Neoplasm Recurrence, Local; Stomach Neoplasms | 1996 |
[A study of arterial infusion chemotherapy for gastric cancer patients with peritoneal metastasis].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Routes; Fluorouracil; Humans; Infusions, Intra-Arterial; Methotrexate; Peritoneal Neoplasms; Stomach Neoplasms; Survival Rate | 1996 |
[Efficacy of implantable injection port for advanced breast cancer patients].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Medroxyprogesterone; Methotrexate; Middle Aged; Tamoxifen | 1996 |
Alternating bolus and continuous infusion 5-fluorouracil: a strategy to overcome resistance to this fluoropyrimidine in advanced colorectal cancer patients.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Fluorouracil; Humans; Infusions, Intravenous; Injections, Intravenous; Leucovorin; Liver Neoplasms; Lung Neoplasms; Methotrexate; Palliative Care; Pilot Projects; Remission Induction; Treatment Outcome; Tumor Cells, Cultured | 1996 |
Increased thromboembolic complications with concurrent tamoxifen and chemotherapy in a randomized trial of adjuvant therapy for women with breast cancer. National Cancer Institute of Canada Clinical Trials Group Breast Cancer Site Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Incidence; Methotrexate; Tamoxifen; Thromboembolism | 1996 |
A prothrombotic state in breast cancer patients treated with adjuvant chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Coagulation; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fibrinolysis; Fluorouracil; Hemostatics; Humans; Methotrexate; Middle Aged; Plasminogen Activator Inhibitor 1; Prothrombin Time; Thrombosis | 1996 |
A phase I trial of a modified, dose intensive FAMTX regimen (high dose 5-fluorouracil+doxorubicin+high dose methotrexate+leucovorin) with oral uridine rescue.
Topics: Administration, Oral; Adult; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fluorouracil; Humans; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasms; Neutropenia; Uridine | 1996 |
Cost-effectiveness of adjuvant chemotherapy with cyclophosphamide+methotrexate+fluorouracil in patients with node-positive breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Sensitivity and Specificity; Survival Rate | 1996 |
Growth factor allows effective dose-intensive regimen in advanced breast cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Methotrexate; Neutropenia; Survival Analysis; Treatment Outcome | 1995 |
[Sequencing of chemotherapy and radiotherapy following breast-preserving treatment of breast carcinoma].
Topics: Antibiotics, Antineoplastic; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leucovorin; Lymphatic Metastasis; Methotrexate; Prednisone; Prognosis; Prospective Studies; Radiotherapy Dosage; Time Factors | 1996 |
Feasibility of non-cisplatin-based induction chemotherapy and concurrent chemoradiotherapy in advanced head and neck cancer.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Pilot Projects; Radiotherapy, Adjuvant; Remission Induction; Survival Analysis; Treatment Outcome | 1996 |
Double biochemical modulation of 5-fluorouracil by methotrexate and levo-folinic acid in the treatment of advanced digestive tract malignancies.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Digestive System Neoplasms; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Survival Rate; Treatment Outcome | 1996 |
Liver function tests and lidocaine metabolism (MEGX test) during i.v. CMF therapy in breast cancer.
Topics: Adult; Aged; Anesthetics, Local; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Fluorouracil; Humans; Lidocaine; Liver Function Tests; Methotrexate; Middle Aged; Prospective Studies | 1996 |
Randomized trial comparing epirubicin, cisplatin, and fluorouracil versus fluorouracil, doxorubicin, and methotrexate in advanced esophagogastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Costs and Cost Analysis; Doxorubicin; Drug Costs; Epirubicin; Esophageal Neoplasms; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Quality of Life; Stomach Neoplasms; Survival Rate | 1997 |
Adjuvant therapy for breast cancer and psychological distress.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Humans; Methotrexate; Stress, Psychological | 1996 |
Mitoxantrone, 5-fluorouracil, and high dose leucovorin (NFL) versus intravenous cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) in first-line chemotherapy for patients with metastatic breast carcinoma: a randomized phase II trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Cyclophosphamide; Female; Fluorouracil; Humans; Leucovorin; Methotrexate; Middle Aged; Mitoxantrone; Survival Rate | 1997 |
Surgical complications related to peri-operative adjuvant chemotherapy in breast cancer. Results of a prospective, controlled, randomized clinical trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bandages; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Drainage; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Infections; Length of Stay; Lymph; Methotrexate; Middle Aged; Postoperative Complications; Prospective Studies; Treatment Outcome; Wound Healing | 1997 |
Activity of standard-dose carboplatin, cyclophosphamide, and etoposide in patients with metastatic breast cancer with previous exposure to anthracyclines.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Carcinoma, Ductal, Breast; Cyclophosphamide; Etoposide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Retreatment; Survival Rate | 1997 |
Filgrastim and lack of support of intensive adjuvant chemotherapy for high-risk breast cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Filgrastim; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Leucovorin; Leukocyte Count; Methotrexate; Middle Aged; Neutropenia; Recombinant Proteins; Survival Rate; Vincristine | 1997 |
Relationship of elevated tumour thymidine phosphorylase in node-positive breast carcinomas to the effects of adjuvant CMF.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Pilot Projects; Survival Rate; Thymidine Phosphorylase; Treatment Outcome | 1997 |
Paclitaxel as first-line treatment for metastatic breast cancer. The Taxol Investigational Trials Group, Australia and New Zealand.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Neoplasm Metastasis; Paclitaxel; Quality of Life | 1997 |
Prognostic importance of thymidylate synthase expression in early breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Humans; Lymph Nodes; Methotrexate; Multivariate Analysis; Neoplasm Proteins; Prognosis; Thymidylate Synthase | 1997 |
Chemical castration induced by adjuvant cyclophosphamide, methotrexate, and fluorouracil chemotherapy causes rapid bone loss that is reduced by clodronate: a randomized study in premenopausal breast cancer patients.
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Density; Breast Neoplasms; Chemotherapy, Adjuvant; Clodronic Acid; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovary; Premenopause; Prospective Studies; Treatment Outcome | 1997 |
Effectiveness of adjuvant chemotherapy in combination with tamoxifen for node-positive postmenopausal breast cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Tamoxifen; Treatment Failure; Treatment Outcome | 1997 |
Randomized trial of cyclophosphamide, methotrexate, and fluorouracil chemotherapy added to tamoxifen as adjuvant therapy in postmenopausal women with node-positive estrogen and/or progesterone receptor-positive breast cancer: a report of the National Canc
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1997 |
Phase II randomized trial of gallium nitrate plus fluorouracil versus methotrexate, vinblastine, doxorubicin, and cisplatin in patients with advanced transitional-cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Female; Fluorouracil; Gallium; Humans; Male; Methotrexate; Middle Aged; Survival Analysis; Treatment Outcome; Urologic Neoplasms; Vinblastine | 1997 |
Adjuvant chemotherapy in operable breast cancer: cyclophosphamide, methotrexate, and fluorouracil versus chlorambucil, methotrexate, and fluorouracil--11-year results of Swiss Group for Clinical Cancer Research trial SAKK 27/82.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Chlorambucil; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Switzerland; Treatment Outcome | 1997 |
The EORTC GI group experience with high-dose infusional 5-FU in colorectal cancer.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dose-Response Relationship, Drug; Fluorouracil; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Stomatitis; Survival Rate; Treatment Outcome | 1996 |
A double-blind, randomized study of two different dosage regimens of intravenous dolasetron in patients receiving high-dose cisplatin chemotherapy.
Topics: Aged; Antiemetics; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Double-Blind Method; Doxorubicin; Etoposide; Female; Fluorouracil; Humans; Indoles; Injections, Intravenous; Leucovorin; Male; Methotrexate; Quinolizines; Vinblastine | 1997 |
Changes of biological features in breast cancer cells determined by primary chemotherapy.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cyclophosphamide; Doxorubicin; ErbB Receptors; Female; Fluorouracil; Humans; Immunohistochemistry; Methotrexate; Middle Aged; Proliferating Cell Nuclear Antigen | 1997 |
Breast conserving therapy in stage I & II breast cancer in Korea.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Korea; Mastectomy, Modified Radical; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Pilot Projects | 1997 |
Hepatic toxicity caused by adjuvant CMF/CNF in breast cancer patients and reversal by tamoxifen.
Topics: Acetyltransferases; Adult; Alkaline Phosphatase; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; gamma-Glutamyltransferase; Humans; Liver Diseases; Methotrexate; Middle Aged; Mitoxantrone; Tamoxifen | 1997 |
[Adjuvant CMF chemotherapy in patients with breast cancer--results on blood coagulation and fibrinolysis].
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Coagulation; Blood Coagulation Factors; Blood Coagulation Tests; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fibrinolysis; Fluorouracil; Humans; Longitudinal Studies; Methotrexate; Thrombosis | 1997 |
Postsurgical sequential methotrexate, fluorouracil, and leucovorin for advanced colorectal carcinoma: a preliminary study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Mitomycin; Postoperative Period; Rectal Neoplasms; Survival Rate; Tegafur; Uracil | 1997 |
Combined treatment of invasive bladder carcinoma with transurethral resection, induction chemotherapy, and radical radiotherapy plus concomitant protracted infusion of cisplatin and 5-fluorouracil: a phase I study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Radiotherapy Dosage; Remission Induction; Urinary Bladder Neoplasms; Vinblastine | 1997 |
Does information from axillary dissection change treatment in clinically node-negative patients with breast cancer? An algorithm for assessment of impact of axillary dissection.
Topics: Adult; Aged; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; False Negative Reactions; Female; Fluorouracil; Hematopoietic Stem Cell Transplantation; Humans; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Mastectomy, Radical; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Staging; Neoplasms, Ductal, Lobular, and Medullary; Prognosis; Sensitivity and Specificity; Tamoxifen | 1997 |
UFT in combination as adjuvant therapy for breast cancer. Grupo Oncologico de Sevilla Seville, Spain.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Combinations; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Postmenopause; Prednimustine; Premenopause; Spain; Survival Analysis; Tamoxifen; Tegafur; Uracil | 1997 |
Multimodality treatment of noninflammatory stage IIIb breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Lymph Node Excision; Mastectomy, Modified Radical; Mastectomy, Radical; Methotrexate; Middle Aged; Survival Analysis; Tamoxifen | 1997 |
A randomized study of paclitaxel versus cyclophosphamide/methotrexate/5-fluorouracil/prednisone in previously untreated patients with advanced breast cancer: preliminary results. Taxol Investigational Trials Group, Australia/New Zealand.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Paclitaxel; Prednisone; Survival Analysis | 1997 |
Pilot study of primary chemotherapy with doxorubicin plus paclitaxel in women with locally advanced or operable breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Paclitaxel; Pilot Projects | 1997 |
Tamoxifen and chemotherapy for lymph node-negative, estrogen receptor-positive breast cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Estrogen Antagonists; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Receptors, Estrogen; Risk; Survival Analysis; Tamoxifen; Treatment Failure; Treatment Outcome | 1997 |
Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy. Danish Breast Cancer Cooperative Group 82b Trial.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy, Modified Radical; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Postoperative Period; Premenopause; Proportional Hazards Models; Survival Analysis | 1997 |
The prognostic significance of sialyl-Tn antigen in women treated with breast carcinoma treated with adjuvant chemotherapy.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Neoplasm; Antigens, Tumor-Associated, Carbohydrate; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Cohort Studies; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Immunoenzyme Techniques; Leucovorin; Methotrexate; Middle Aged; Prognosis; Vinblastine | 1997 |
Lack of effectiveness of adjuvant alternating chemotherapy in node-positive, estrogen-receptor-negative premenopausal breast cancer patients: results of a multicentric Italian study. The Breast Cancer Adjuvant Chemo-Hormone Therapy Cooperative Group (GROC
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Mitomycin; Premenopause; Receptors, Estrogen; Survival Analysis; Vincristine; Vindesine | 1997 |
p53 immunohistochemical staining and survival after adjuvant chemotherapy for breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Immunohistochemistry; Methotrexate; Middle Aged; Multivariate Analysis; Staining and Labeling; Survival Analysis; Treatment Outcome; Tumor Suppressor Protein p53 | 1997 |
Primary chemotherapy in operable breast cancer: eight-year experience at the Milan Cancer Institute.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Disease Progression; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Prospective Studies; Survival Analysis; Treatment Outcome | 1998 |
Mitoxantrone, 5-fluorouracil and high-dose leucovorin (NFL) in the treatment of metastatic breast cancer: randomized comparison to cyclophosphamide, methotrexate and 5-fluorouracil (CMF) and attempts to improve efficacy by adding paclitaxel.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Leucovorin; Methotrexate; Middle Aged; Mitoxantrone; Paclitaxel | 1997 |
Modulation of 5-fluorouracil with methotrexate and low-dose N-(phosphonacetyl)-L-aspartate in patients with advanced colorectal cancer. Results of a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colorectal Neoplasms; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Phosphonoacetic Acid; Survival Analysis; Treatment Outcome | 1997 |
High-dose chemotherapy consolidation with autologous stem cell rescue in metastatic breast cancer: a 10-year experience.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Methotrexate; Middle Aged; Mitoxantrone; Recurrence; Survival Rate; Thiotepa; Time Factors; Transplantation, Autologous; Vincristine | 1998 |
Autologous stem cell transplantation for aggressive non-Hodgkin's lymphomas in first complete or partial remission: a retrospective analysis of the outcome of 52 patients according to the age-adjusted International Prognostic Index.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Fluorouracil; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Prognosis; Remission Induction; Retrospective Studies; Transplantation, Autologous; Treatment Outcome; Vincristine | 1998 |
Phase III randomized comparison of postoperative adjuvant chemotherapy with 2-year oral UFT (uracil/tegafur) versus six-cycle CMF (cyclophosphamide/methotrexate/5-fluorouracil) in high-risk node-negative breast cancer patients.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Tegafur; Uracil | 1998 |
Is p53 a protein that predicts the response to chemotherapy in node negative breast cancer?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Tumor Suppressor Protein p53 | 1998 |
Double modulation of 5-fluorouracil by methotrexate and high-dose L-leucovorin in advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Survival Analysis | 1998 |
Dose-dense paclitaxel-containing adjuvant therapy for breast cancer.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Paclitaxel; Prospective Studies | 1998 |
[Sequential chemotherapy with methotrexate and 5-fluorouracil for advanced gastric cancer].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Fluorouracil; Humans; Injections, Intravenous; Leucovorin; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 1998 |
Clinical implications of serum levels of soluble CD30 in 70 adult anaplastic large-cell lymphoma patients.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Fluorouracil; Humans; Ki-1 Antigen; Leucovorin; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Phenotype; Prednisone; Prognosis; Survival Analysis; Vincristine | 1998 |
Vinorelbine, bleomycin and methotrexate as a salvage therapy for patients with head and neck squamous carcinoma in relapse after cisplatin/fluorouracil.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Salvage Therapy; Vinblastine; Vinorelbine | 1998 |
Eastern Cooperative Oncology Group randomized trials of observation versus maintenance therapy for patients with metastatic breast cancer in complete remission following induction treatment.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Fluoxymesterone; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prednisone; Remission Induction; Survival Rate; Tamoxifen | 1998 |
Long-term follow-up of a randomized trial on adjuvant chemotherapy and hormonal therapy in locally advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Survival Rate; Vincristine | 1998 |
CMF + radiotherapy in the primary treatment of operable breast cancer: preliminary results of a phase II pilot study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Feasibility Studies; Female; Fluorouracil; Humans; Mastectomy, Modified Radical; Methotrexate; Middle Aged; Pilot Projects; Radiotherapy Dosage | 1998 |
Very low-dose adjuvant chemotherapy in steroid receptor negative stage I breast cancer patients. Austrian Breast Cancer Study Group.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Treatment Outcome; Vincristine | 1998 |
Early stem cell transplantation for chronic lymphocytic leukaemia: a chance for cure?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chlorambucil; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Fluorouracil; Follow-Up Studies; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Hydrocortisone; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Melphalan; Methotrexate; Methylprednisolone; Middle Aged; Mitomycins; Prednisone; Prospective Studies; Treatment Outcome; Vincristine | 1998 |
Cytotoxic and antiproliferative activity of the CMF regimen administered in association with tamoxifen as primary chemotherapy in breast cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Ki-67 Antigen; Methotrexate; Middle Aged; Receptors, Estrogen; Staining and Labeling; Tamoxifen; Treatment Outcome | 1998 |
Sixteen-week multidrug regimen versus cyclophosphamide, doxorubicin, and fluorouracil as adjuvant therapy for node-positive, receptor-negative breast cancer: an Intergroup study.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Quality of Life; Surveys and Questionnaires; Survival Analysis; Treatment Outcome | 1998 |
Cyclophosphamide, methotrexate and infusional 5-fluorouracil (infusional CMF) in metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis | 1998 |
A phase II trial of carboplatin, methotrexate and fluorouracil in fluorouracil-pretreated colorectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Salvage Therapy | 1998 |
Quality adjusted survival analysis with repeated quality of life measures.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Health Status; Humans; Methotrexate; Middle Aged; Quality of Life; Quality-Adjusted Life Years; Survival Analysis; Time Factors | 1998 |
Randomized trial of intensive cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer. National Cancer Institute of Canada Clinical
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Premenopause; Survival Rate | 1998 |
Prognostic impact of amenorrhoea after adjuvant chemotherapy in premenopausal breast cancer patients with axillary node involvement: results of the International Breast Cancer Study Group (IBCSG) Trial VI.
Topics: Adult; Age Distribution; Aged; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Premenopause | 1998 |
[A randomized controlled trial with methotrexate (MTX), 5-fluorouracil (5-FU) and pirarubicin (THP) vs 5-FU alone in advanced or recurrent gastric carcinoma. Tokai Hokuriku THP Study Group].
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Stomach Neoplasms; Survival Analysis | 1998 |
Oral doxifluridine plus levoleucovorin in elderly patients with advanced breast cancer.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Floxuridine; Fluorouracil; Humans; Leucovorin; Methotrexate; Neoplasm Staging | 1998 |
[Comparison of adjuvant chemotherapy in breast carcinoma with a combination of cyclophosphamide, methotrexate, 5-fluorouracil (CMF) and AC (doxorubicin, cyclophosphamide). Initial results of a national cooperative study].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Prospective Studies | 1998 |
Phase III randomized comparison of postoperative adjuvant chemotherapy with 2-year oral uracil/tegafur versus 6-cycle cyclophosphamide/methotrexate/5-fluorouracil in high-risk node-negative breast cancer patients.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Risk; Survival Analysis; Tegafur; Uracil | 1998 |
Biochemical modulation of 5-fluorouracil by methotrexate in patients with advanced gastric carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Prospective Studies; Stomach Neoplasms; Survival Analysis; Treatment Outcome | 1998 |
The importance of the histologic grade of invasive breast carcinoma and response to chemotherapy.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Cohort Studies; Cyclophosphamide; Disease-Free Survival; Estrogen Antagonists; Female; Fluorouracil; Forecasting; Humans; Lymph Nodes; Mastectomy; Methotrexate; Neoplasm Invasiveness; Postmenopause; Prednisone; Premenopause; Prognosis; Proportional Hazards Models; Survival Rate; Tamoxifen | 1998 |
Pharmacokinetic interaction between ondansetron and cyclophosphamide during high-dose chemotherapy for breast cancer.
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carmustine; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Fluorouracil; Hematopoietic Stem Cell Transplantation; Humans; Methotrexate; Ondansetron; Prospective Studies; Transplantation Conditioning | 1998 |
Schedule-selective biochemical modulation of 5-fluorouracil: a phase II study in advanced colorectal cancer.
Topics: Adult; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Rectal Neoplasms | 1995 |
Survival advantage of adjuvant chemotherapy in high-risk node-negative breast cancer: ten-year analysis--an intergroup study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Methotrexate; Middle Aged; Prednisone; Risk; Survival Analysis | 1998 |
MACOP-B and involved field radiation therapy is an effective therapy for primary mediastinal large B-cell lymphoma with sclerosis.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Fluorouracil; Humans; Leucovorin; Lymphoma, B-Cell; Male; Mediastinal Neoplasms; Methotrexate; Middle Aged; Prednisone; Sclerosis; Survival Rate; Treatment Outcome; Vincristine | 1998 |
Adjuvant treatment of breast cancer: a pilot immunochemotherapy study with CMF, interleukin-2 and interferon alpha.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Interferon-alpha; Interleukin-2; Killer Cells, Natural; Leukocytes; Methotrexate; Pilot Projects | 1998 |
Phase I-II study of 5-fluorouracil, leucovorin, doxorubicin, methotrexate, and long-term oral etoposide (FLAME) in unresectable or metastatic gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Etoposide; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Stomach Neoplasms; Survival Analysis | 1998 |
[Primary chemotherapy of metastatic breast carcinoma with bendamustine hydrochloride, methotrexate and fluorouracil versus cyclophosphamide, methotrexate and fluorouracil].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Nitrogen Mustard Compounds; Pilot Projects; Salvage Therapy; Survival Rate; Treatment Outcome | 1998 |
Cognitive deficits after postoperative adjuvant chemotherapy for breast carcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Attention; Breast Neoplasms; Chemotherapy, Adjuvant; Cognition Disorders; Cyclophosphamide; Depression; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neuropsychological Tests; Quality of Life; Socioeconomic Factors | 1999 |
Long term follow-up of women treated with 16-week, dose-intensive adjuvant chemotherapy for high risk breast carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease Progression; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Regression Analysis; Survival Rate; Vincristine | 1999 |
A phase II trial of cisplatin, methotrexate, levofolinic acid, and 5-fluorouracil in the treatment of patients with locally advanced, metastatic squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Radionuclide Imaging; Survival Analysis | 1999 |
High rate of clinical complete response to weekly outpatient neoadjuvant chemotherapy in oral carcinoma patients using a new regimen of cisplatin, 5-fluorouracil, and bleomycin alternating with methotrexate and epirubicin.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Patient Compliance; Prospective Studies; Treatment Outcome | 1999 |
Adjuvant dose-intense chemotherapy with peripheral blood stem cell support in stage II-III breast cancer with five to nine involved axillary lymph nodes.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Chemotherapy, Adjuvant; Doxorubicin; Female; Fluorouracil; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Staging; Survival Analysis | 1999 |
Carboplatin, methotrexate and 5-fluorouracil in combination with medroxyprogesterone acetate (JMF-M) in the treatment of advanced or recurrent endometrial carcinoma: A Hellenic cooperative oncology group study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Drug Synergism; Endometrial Neoplasms; Female; Fluorouracil; Humans; Medroxyprogesterone Acetate; Methotrexate; Middle Aged; Prospective Studies; Treatment Outcome | 1999 |
Doxorubicin versus methotrexate both combined with cyclophosphamide, 5-fluorouracil and tamoxifen in postmenopausal patients with advanced breast cancer--a randomised study with more than 10 years follow-up from the Danish Breast Cancer Cooperative Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease Progression; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Postmenopause; Survival Analysis; Tamoxifen | 1999 |
[Intra-arterial chemotherapy via reservoir system for advanced bladder cancer and prostate cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Catheters, Indwelling; Cisplatin; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Prostatic Neoplasms; Urinary Bladder Neoplasms | 1999 |
The relation between erythropoietin, hematocrit and hemoglobin in breast cancer patients on non-nephrotoxic chemotherapy.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Enzyme-Linked Immunosorbent Assay; Erythropoietin; Female; Fluorouracil; Hematocrit; Hemoglobins; Humans; Methotrexate; Neoplasm Staging; Prognosis; Sensitivity and Specificity | 1998 |
The relationship between serum levels of erythropoietin (EPO) and insulin-like growth factor-1 (ILGF-1) and hematocrit (HCT) in breast cancer patients receiving non-nephrotoxic chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Confidence Intervals; Cyclophosphamide; Doxorubicin; Erythropoietin; Female; Fluorouracil; Hematocrit; Humans; Insulin-Like Growth Factor I; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Sensitivity and Specificity | 1998 |
A pilot study of adjuvant chemotherapy with double modulation of 5-fluorouracil by methotrexate and leucovorin in gastric cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Pilot Projects; Stomach Neoplasms | 1999 |
Interaction of tamoxifen with concurrent cytotoxic adjuvant treatment affects lymphocytes and lymphocyte subsets counts in breast cancer patients.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocyte Subsets; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Drug Interactions; Female; Flow Cytometry; Fluorouracil; Humans; Methotrexate; Middle Aged; T-Lymphocyte Subsets; Tamoxifen | 1999 |
Neo-adjuvant chemotherapy for operable breast cancer induces apoptosis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Predictive Value of Tests; Prognosis; Receptors, Estrogen; Survival Rate | 1999 |
Prevention of febrile leucopenia after chemotherapy in high-risk breast cancer patients: no significant difference between granulocyte-colony stimulating growth factor or ciprofloxacin plus amphotericin B.
Topics: Adult; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Ciprofloxacin; Costs and Cost Analysis; Cyclophosphamide; Drug Therapy, Combination; Epirubicin; Female; Fever; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Length of Stay; Leukopenia; Methotrexate; Middle Aged; Neoplasm Metastasis; Netherlands; Prospective Studies; Recombinant Proteins | 1999 |
Long-term survival after epirubicin, cisplatin and fluorouracil for gastric cancer: results of a randomized trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Epirubicin; Esophageal Neoplasms; Fluorouracil; Humans; Methotrexate; Prospective Studies; Stomach Neoplasms; Survival Analysis | 1999 |
Effect of c-erbB(2) and estrogen receptor status on survival of women with primary breast cancer treated with adjuvant cyclophosphamide/methotrexate/fluorouracil.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Middle Aged; Predictive Value of Tests; Receptor, ErbB-2; Receptors, Estrogen; Regression Analysis; Survival Rate; Time Factors | 1999 |
Mortality during adjuvant treatment of early breast cancer with cyclophosphamide, methotrexate, and fluorouracil. International Breast Cancer Study Group.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Postmenopause; Premenopause | 1999 |
Granisetron compared with prednisolone plus metopimazine as anti-emetic prophylaxis during multiple cycles of moderately emetogenic chemotherapy.
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dopamine Antagonists; Double-Blind Method; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Glucocorticoids; Granisetron; Humans; Isonipecotic Acids; Methotrexate; Middle Aged; Nausea; Prednisolone; Serotonin Antagonists; Vomiting | 1999 |
[Usefulness of ramosetron hydrochloride on nausea and vomiting in CMF or CEF therapy for breast cancer].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Appetite; Benzimidazoles; Breast Neoplasms; Breast Neoplasms, Male; Cisplatin; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Nausea; Safety; Serotonin Antagonists; Treatment Outcome; Vomiting | 1999 |
Mobilization of peripheral blood progenitor cells in patients with breast cancer: a prospective randomized trial comparing rhG-CSF with the combination of rhG-CSF plus rhEpo after VIP-E chemotherapy.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Epirubicin; Erythropoietin; Etoposide; Female; Fluorouracil; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Prospective Studies; Recombinant Proteins; Transplantation Conditioning; Transplantation, Autologous | 1999 |
Leucocyte nadir as a marker for chemotherapy efficacy in node-positive breast cancer treated with adjuvant CMF.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Drug Monitoring; Female; Fluorouracil; Follow-Up Studies; Humans; Leukocyte Count; Leukopenia; Life Tables; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Staging; Predictive Value of Tests; Receptors, Progesterone; Survival Rate; Time Factors | 1999 |
Treatment-related toxicity from a randomized trial of the sequencing of doxorubicin and radiation therapy in patients treated for early stage breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arm; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Edema; Female; Fluorouracil; Heart; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Prospective Studies; Radiotherapy | 1999 |
Chemotherapy for operable gastric cancer: results of the Dutch randomised FAMTX trial. The Dutch Gastric Cancer Group (DGCG).
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Preoperative Care; Stomach Neoplasms; Treatment Outcome | 1999 |
Randomized trial to compare the efficacy and toxicity of cyclophosphamide, methotrexate and 5-fluorouracil (CMF) with methotrexate mitoxantrone (MM) in advanced carcinoma of the breast.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitoxantrone; Quality of Life; Survival Analysis | 1999 |
Laryngeal preservation by treatment with induction chemotherapy and radiotherapy protocol for stage III & IV carcinoma larynx--results of a pilot study.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemotherapy, Adjuvant; Cisplatin; Fluorouracil; Humans; Laryngeal Neoplasms; Laryngectomy; Male; Methotrexate; Middle Aged; Neoplasm Staging; Pilot Projects; Survival Rate | 1999 |
Prognostic and predictive factors for patients with metastatic breast cancer undergoing aggressive induction therapy followed by high-dose chemotherapy with autologous stem-cell support.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Doxorubicin; Estrogen Antagonists; Female; Fluorouracil; Hematopoietic Stem Cell Transplantation; Humans; Methotrexate; Middle Aged; Predictive Value of Tests; Prognosis; Retrospective Studies; Survival Analysis; Tamoxifen; Treatment Outcome | 1999 |
A phase II trial of methotrexate, cisplatin, 5-fluorouracil, and leucovorin in the treatment of invasive and metastatic urothelial carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Female; Fluorouracil; Follow-Up Studies; Humans; Kidney Neoplasms; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Survival Rate; Urinary Bladder Neoplasms | 1999 |
A phase II study of Tomudex alternated with methotrexate, 5-fluorouracil, leucovorin in first-line chemotherapy of metastatic colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Prognosis; Quinazolines; Survival Rate; Thiophenes; Treatment Outcome | 1999 |
Actual 5-year survival of patients with stage IIIB breast carcinoma: phase II trial of methotrexate, vinblastine, adriamycin, cisplatin, and folinic acid.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Prognosis; Survival Analysis; Vinblastine | 1999 |
How do patients with aggressive non-Hodgkin's lymphoma treated with third-generation regimens (MACOP-B and F-MACHOP) fare in the long-term?
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Retrospective Studies; Salvage Therapy; Treatment Outcome; Vincristine | 1999 |
Randomized trial of low-dose chemotherapy added to tamoxifen in patients with receptor-positive and lymph node-positive breast cancer.
Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Recurrence; Survival Rate; Tamoxifen; Vincristine | 1999 |
Initial paclitaxel improves outcome compared with CMFP combination chemotherapy as front-line therapy in untreated metastatic breast cancer.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neutropenia; Paclitaxel; Prednisone; Quality of Life | 1999 |
Concurrent CMF and radiation therapy for early stage breast cancer: results of a pilot study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Pilot Projects; Radiotherapy Dosage | 1999 |
Comparison of CMF (cyclophosphamide, methotrexate, and 5-fluorouracil) with a rotational crossing and a sequential intensification regimen in advanced breast cancer: a prospective randomized study.
Topics: Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prospective Studies; Remission Induction; Survival Rate; Treatment Outcome | 1999 |
Docetaxel compared with sequential methotrexate and 5-fluorouracil in patients with advanced breast cancer after anthracycline failure: a randomised phase III study with crossover on progression by the Scandinavian Breast Group.
Topics: Adult; Aged; Algorithms; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cross-Over Studies; Disease Progression; Docetaxel; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Paclitaxel; Patient Compliance; Taxoids; Treatment Failure | 1999 |
Randomized 2 x 2 trial evaluating hormonal treatment and the duration of chemotherapy in node-positive breast cancer patients: an update based on 10 years' follow-up. German Breast Cancer Study Group.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Germany; Humans; Methotrexate; Middle Aged; Multivariate Analysis; Survival Rate; Tamoxifen; Time Factors | 2000 |
Adjuvant chemotherapy with a combination of mitoxantrone, methotrexate, 5-fluorouracil for node-positive breast cancer: phase II pilot study.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Chemotherapy, Adjuvant; Child; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Mitoxantrone | 1999 |
Enhancement of fluorouracil uptake in human colorectal and gastric cancers by interferon or by high-dose methotrexate: An in vivo human study using noninvasive (19)F-magnetic resonance spectroscopy.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Interactions; Female; Fluorine Compounds; Fluorouracil; Humans; Infusions, Intravenous; Interferon-alpha; Liver Neoplasms; Magnetic Resonance Spectroscopy; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 2000 |
An original accelerated radiotherapy schedule in stage III to IV head and neck cancers. Results in a multicenter setting.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Dose Fractionation, Radiation; Doxorubicin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Patient Selection; Prednisone; Radiotherapy; Remission Induction; Survival Rate; Vincristine | 2000 |
Randomized trial of omeprazole or ranitidine versus placebo in the prevention of chemotherapy-induced gastroduodenal injury.
Topics: Adult; Aged; Anti-Ulcer Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Duodenal Ulcer; Female; Fluorouracil; Gastric Mucosa; Histamine H2 Antagonists; Humans; Intestinal Mucosa; Male; Methotrexate; Middle Aged; Omeprazole; Ranitidine; Stomach Ulcer | 2000 |
Tamoxifen in high-risk premenopausal women with primary breast cancer receiving adjuvant chemotherapy. Report from the Danish Breast Cancer co-operative Group DBCG 82B Trial.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy, Modified Radical; Methotrexate; Middle Aged; Premenopause; Tamoxifen | 1999 |
Subclinical cardiotoxicity following adjuvant dose-escalated FEC, high-dose chemotherapy, or CMF in breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Epirubicin; Female; Fluorouracil; Heart; Hematopoietic Stem Cell Transplantation; Humans; Methotrexate; Middle Aged | 2000 |
Burdens and benefits of adjuvant cyclophosphamide, methotrexate, and fluorouracil and tamoxifen for elderly patients with breast cancer: the International Breast Cancer Study Group Trial VII.
Topics: Age Factors; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Infusions, Intravenous; Methotrexate; Middle Aged; Postmenopause; Tamoxifen | 2000 |
Randomized trial on the effect of radiotherapy in addition to 6 cycles CMF in node-positive breast-cancer patients. The German Breast-Cancer Study Group.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Salvage Therapy; Survival Analysis | 2000 |
A feasibility study evaluating docetaxel-based sequential and combination regimens in the adjuvant therapy of node-positive breast cancer.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Confidence Intervals; Cyclophosphamide; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Feasibility Studies; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Staging; Paclitaxel; Survival Rate; Taxoids; Treatment Outcome | 2000 |
Adjuvant sequential chemotherapy with doxorubicin plus cyclophosphamide, methotrexate, and fluorouracil (ACMF) with concurrent radiotherapy in resectable advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Mastectomy, Modified Radical; Methotrexate; Middle Aged; Neutropenia | 2000 |
[Dose intensified adjuvant chemotherapy in high risk breast carcinoma with 4-9 positive lymph nodes].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Staging; Prospective Studies | 2000 |
[Consolidation radiotherapy after high-dose chemotherapy and autologous bone marrow transplantation in patients with advanced breast cancer].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Retrospective Studies; Time Factors | 2000 |
Adjuvant CMF-chemotherapy and haemostasis. Effect of "classical" and "modified" adjuvant CMF-chemotherapy on blood coagulation fibrinolysis in patients with breast cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Coagulation; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fibrinolysis; Fluorouracil; Hemostasis; Humans; Infusions, Intravenous; Methotrexate; Middle Aged; Probability; Statistics, Nonparametric | 2000 |
[Adjuvant chemotherapy with anthracyclines in comparison with the standard combination of CMF in breast cancer with high risk of relapse].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Risk; Survival Analysis; Treatment Outcome | 2000 |
Modulation of fluorouracil by methotrexate, leucovorin, and cisplatin (M-FLP) in the treatment of advanced pancreatic cancer: a phase II study of the Italian Oncology Group for Clinical Research (GOIRC).
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; Immunologic Factors; Italy; Leucovorin; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Survival Rate; Treatment Failure | 2000 |
Dose-finding and pharmacologic study of chronic oral idarubicin therapy in metastatic breast cancer patients.
Topics: Administration, Oral; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Cyclophosphamide; Daunorubicin; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Idarubicin; Maximum Tolerated Dose; Methotrexate; Middle Aged; Neoplasm Metastasis; Paclitaxel; Taxoids; Time Factors | 2000 |
Sequence-dependent toxicity profile in modified FAMTX (fluorouracil-adriamycin-methotrexate) chemotherapy with lenograstim support for advanced gastric cancer: a feasibility study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cardia; Doxorubicin; Drug Administration Schedule; Esophagogastric Junction; Feasibility Studies; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Lenograstim; Male; Methotrexate; Middle Aged; Neutropenia; Recombinant Proteins; Stomach Neoplasms | 2000 |
Final results of a randomized phase III trial of sequential high-dose methotrexate, fluorouracil, and doxorubicin versus etoposide, leucovorin, and fluorouracil versus infusional fluorouracil and cisplatin in advanced gastric cancer: A trial of the Europe
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Etoposide; Female; Fluorouracil; Humans; Leucovorin; Levoleucovorin; Male; Methotrexate; Middle Aged; Proportional Hazards Models; Stomach Neoplasms; Survival Analysis | 2000 |
Cyclophosphamide, methotrexate, and fluorouracil versus tamoxifen plus ovarian suppression as adjuvant treatment of estrogen receptor-positive pre-/perimenopausal breast cancer patients: results of the Italian Breast Cancer Adjuvant Study Group 02 randomi
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Goserelin; Humans; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Ovariectomy; Premenopause; Receptors, Estrogen; Survival Analysis; Tamoxifen | 2000 |
Cell proliferation and outcome following doxorubicin plus CMF regimens in node-positive breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cell Division; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease Progression; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Italy; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Mitotic Index; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Prognosis; Proportional Hazards Models; Prospective Studies; Receptors, Estrogen; Survival Analysis; Treatment Outcome | 2000 |
Quality of life in patients with metastatic breast cancer receiving either docetaxel or sequential methotrexate and 5-fluorouracil. A multicentre randomised phase III trial by the Scandinavian breast group.
Topics: Algorithms; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Docetaxel; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Paclitaxel; Quality of Life; Taxoids | 2000 |
[Randomized comparative study of CMF (cyclophosphamide, methotrexate and 5-fluorouracil) and UFT-tamoxifen regimens as adjuvant chemotherapy after surgery for breast cancer: Tochigi Prefectural Study Group for Post-Breast Cancer Adjuvant Chemotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Prospective Studies; Quality of Life; Survival Rate; Tamoxifen; Tegafur; Uracil | 2000 |
Long-term quality of life in premenopausal women with node-negative localized breast cancer treated with or without adjuvant chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Premenopause; Quality of Life; Surveys and Questionnaires; Survivors; Time Factors | 2000 |
Disease-free survival advantage of adjuvant cyclophosphamide, methotrexate, and fluorouracil in patients with node-negative, rapidly proliferating breast cancer: a randomized multicenter study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Patient Compliance; Prospective Studies; Risk Factors | 2000 |
Content of epidermal growth factor receptor in metastatic breast cancer: its role in endocrine sensitivity prediction.
Topics: Adult; Aminoglutethimide; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; ErbB Receptors; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Ovariectomy; Predictive Value of Tests; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Survival Analysis; Tamoxifen; Treatment Outcome | 2000 |
Late treatment-related morbidity in breast cancer patients randomized to postmastectomy radiotherapy and systemic treatment versus systemic treatment alone.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Node Excision; Lymphedema; Mastectomy; Methotrexate; Middle Aged; Morbidity; Radiotherapy, Adjuvant; Range of Motion, Articular; Shoulder; Tamoxifen; Telangiectasis | 2000 |
Multivariate analysis of pulmonary fibrosis after electron beam irradiation for postmastectomy chest wall and regional lymphatics: evidence for non-dosimetric factors.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Chi-Square Distribution; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Radiation; Epirubicin; Female; Fluorouracil; Humans; Incidence; Logistic Models; Lymph Nodes; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Staging; Prospective Studies; Pulmonary Fibrosis; Radiation Dosage; Radiation Tolerance; Radiotherapy, Adjuvant; Radiotherapy, High-Energy; Risk Factors; Statistics, Nonparametric; Thorax | 2000 |
[Long-term results of preoperative chemotherapy for operable breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Postoperative Care; Preoperative Care; Survival Rate | 1997 |
Double modulation of 5-fluorouracil by leucovorin and low-dose methotrexate in advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Survival Analysis | 2000 |
Intra-arterial chemotherapy in locally advanced or recurrent carcinomas of the penis and anal canal: an active treatment modality with curative potential.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents; Anus Neoplasms; Arteries; Bleomycin; Cisplatin; Fluorouracil; Follow-Up Studies; Humans; Injections; Male; Methotrexate; Middle Aged; Mitomycin; Neoplasm Recurrence, Local; Neutropenia; Penile Neoplasms; Skin Diseases; Treatment Outcome | 2000 |
Neoadjuvant tamoxifen for operable breast cancer: a need for phase III studies?
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Case-Control Studies; Clinical Trials, Phase III as Topic; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoadjuvant Therapy; Pilot Projects; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Survival Analysis; Tamoxifen | 2000 |
Adjuvant doxorubicin and cyclophosphamide versus cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy in premenopausal women with axillary lymph node positive breast carcinoma.
Topics: Adult; Anemia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Leukopenia; Lymph Nodes; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Premenopause; Survival Analysis; Time Factors; Treatment Outcome | 2000 |
Schedule specific biochemical modulation of 5-fluorouracil in advanced colorectal cancer: a randomized study. GISCAD, IOR and collaborating centers.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Conjunctivitis; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Gastrointestinal Diseases; Humans; Infusions, Intravenous; Injections, Intravenous; Leucovorin; Life Tables; Male; Methotrexate; Middle Aged; Neutropenia; Patient Compliance; Quality of Life; Salvage Therapy; Survival Analysis; Treatment Outcome | 2000 |
Tamoxifen and chemotherapy for axillary node-negative, estrogen receptor-negative breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-23.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cisplatin; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Patient Compliance; Placebos; Receptors, Estrogen; Survival Analysis; Tamoxifen | 2001 |
Dose-intensive epirubicin-based chemotherapy is superior to an intensive intravenous cyclophosphamide, methotrexate, and fluorouracil regimen in metastatic breast cancer: a randomized multinational study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Injections, Intravenous; Methotrexate; Middle Aged; Neoplasm Metastasis; Survival Analysis | 2001 |
Response to cyclophosphamide, methotrexate, and fluorouracil in lymph node-positive breast cancer according to HER2 overexpression and other tumor biologic variables.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Biomarkers; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Immunohistochemistry; Lymphatic Metastasis; Mastectomy, Radical; Methotrexate; Middle Aged; Proportional Hazards Models; Prospective Studies; Receptor, ErbB-2; Survival Analysis | 2001 |
Prediction of node-negative breast cancer outcome by histologic grading and S-phase analysis by flow cytometry: an Eastern Cooperative Oncology Group Study (2192).
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Flow Cytometry; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Medical Futility; Methotrexate; Multivariate Analysis; Predictive Value of Tests; Prednisone; Proportional Hazards Models; Reproducibility of Results; S Phase; Survival Rate | 2001 |
Thymidine kinase and thymidylate synthase in advanced breast cancer: response to tamoxifen and chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Drug Resistance, Neoplasm; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Tamoxifen; Thymidine Kinase; Thymidylate Synthase | 2001 |
5-fluorouracil modulated by leucovorin, methotrexate and mitomycin: highly effective, low-cost chemotherapy for advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Conjunctivitis; Diarrhea; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mitomycin; Mouth Mucosa; Nausea; Stomatitis; Survival Analysis; Treatment Outcome; Vomiting | 2001 |
Variations in dose and dose intensity of adjuvant CMF chemotherapy for breast cancer throughout the UK.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Surveys and Questionnaires; United Kingdom | 2000 |
Exercise reduces daily fatigue in women with breast cancer receiving chemotherapy.
Topics: Activities of Daily Living; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Exercise Therapy; Fatigue; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Treatment Outcome | 2001 |
Intra-arterial plus i.v. chemotherapy for advanced bulky squamous cell carcinoma of the buccal mucosa.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Drug Eruptions; Dyspnea; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Neoplasm Recurrence, Local; Radiotherapy, Adjuvant; Stomatitis; Survival Rate; Treatment Outcome | 2001 |
Long-term prognosis of breast cancer patients with 10 or more positive lymph nodes treated with CMF.
Topics: Adult; Age Distribution; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Prognosis | 2001 |
Combined chemo- and radiotherapy vs. radiotherapy alone in the treatment of primary, nonresectable adenocarcinoma of the rectum.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Radiotherapy; Rectal Neoplasms; Survival Rate | 2001 |
Effect of endocrine treatment on sexuality in premenopausal breast cancer patients: a prospective randomized study.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Drug Therapy, Combination; Female; Fluorouracil; Goserelin; Humans; Methotrexate; Middle Aged; Patient Satisfaction; Premenopause; Sexual Dysfunction, Physiological; Tamoxifen | 2001 |
[Cisplatin and vinorelbine therapy of previously treated advanced breast cancer (preliminary studies)].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Disease Progression; Doxorubicin; Female; Fluorouracil; Hematologic Diseases; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Middle Aged; Skin Neoplasms; Treatment Outcome; Vinblastine; Vinorelbine | 2001 |
Phase III trial comparing two dose levels of epirubicin combined with cyclophosphamide with cyclophosphamide, methotrexate, and fluorouracil in node-positive breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Belgium; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Proportional Hazards Models; Statistics, Nonparametric; Survival Rate | 2001 |
Randomized adjuvant chemotherapy trial in high-risk, lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type 1.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymph Nodes; Menopause; Methotrexate; Middle Aged; Neoplasm Staging; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Predictive Value of Tests; Prognosis; Risk Factors; Time Factors; Treatment Outcome; Urokinase-Type Plasminogen Activator | 2001 |
Adjuvant high-dose medroxyprogesterone acetate for early breast cancer: 13 years update in a multicentre randomized trial.
Topics: Age Factors; Analysis of Variance; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Fluorouracil; Follow-Up Studies; Humans; Injections, Intramuscular; Medroxyprogesterone Acetate; Methotrexate; Middle Aged; Neoplasm Staging; Survival Rate; Treatment Outcome | 2001 |
CMF (cyclophosphamide, methotrexate, 5-fluorouracil) versus cnf (cyclophosphamide, mitoxantrone, 5-fluorouracil) as adjuvant chemotherapy for stage II lymph-node positive breast cancer: a phase III randomized multicenter study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Staging; Survival Analysis | 2001 |
HER-2 and topo-isomerase IIalpha as predictive markers in a population of node-positive breast cancer patients randomly treated with adjuvant CMF or epirubicin plus cyclophosphamide.
Topics: Adult; Aged; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Confidence Intervals; Cyclophosphamide; DNA Topoisomerases, Type II; DNA-Binding Proteins; Epirubicin; Female; Fluorouracil; Genes, erbB-2; Humans; Methotrexate; Middle Aged; Predictive Value of Tests; Prognosis; Receptor, ErbB-2; Retrospective Studies; Treatment Outcome | 2001 |
Influence of endocrine-related factors on response to perioperative chemotherapy for patients with node-negative breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Postmenopause; Proportional Hazards Models; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Analysis | 2001 |
Randomized, open-label, phase II trial of oral capecitabine (Xeloda) vs. a reference arm of intravenous CMF (cyclophosphamide, methotrexate and 5-fluorouracil) as first-line therapy for advanced/metastatic breast cancer.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Cyclophosphamide; Deoxycytidine; Diarrhea; Disease Progression; Female; Fluorouracil; Humans; Infusions, Intravenous; Methotrexate; Middle Aged; Neoplasm Metastasis; Peripheral Nervous System Diseases; Survival Analysis; Treatment Outcome | 2001 |
Long-term impact of chemotherapy-induced ovarian failure on bone mineral density (BMD) in premenopausal breast cancer patients. The effect of adjuvant clodronate treatment.
Topics: Absorptiometry, Photon; Administration, Oral; Adult; Amenorrhea; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Bone Demineralization, Pathologic; Bone Density; Breast Neoplasms; Chemotherapy, Adjuvant; Clodronic Acid; Cyclophosphamide; Female; Fluorouracil; Follicle Stimulating Hormone; Humans; Methotrexate; Middle Aged; Ovarian Diseases; Prospective Studies | 2001 |
[Clinical study on shenmai injection in promoting postoperative recovery in patients of breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drugs, Chinese Herbal; Female; Fluorouracil; Humans; Injections, Intravenous; Mastectomy, Radical; Methotrexate; Middle Aged; Postoperative Period | 2000 |
[Prospective randomized trial on the efficacy of adjuvant endocrine therapy for ER-positive breast cancer patients after radical mastectomy].
Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Doxorubicin; Estrogen Antagonists; Female; Fluorouracil; Humans; Mastectomy, Radical; Methotrexate; Middle Aged; Ovariectomy; Prospective Studies; Selective Estrogen Receptor Modulators; Tamoxifen; Vincristine | 2001 |
Phase II study of sequential high-dose methotrexate and fluorouracil combined with doxorubicin as a neoadjuvant chemotherapy for scirrhous gastric cancer.
Topics: Adenocarcinoma, Scirrhous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Feasibility Studies; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Stomach Neoplasms; Survival Rate; Treatment Outcome | 2001 |
Phase III trial of fluorouracil, interferon alpha-2b, and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in metastatic or unresectable urothelial cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Female; Fluorouracil; Humans; Interferon alpha-2; Interferon-alpha; Male; Methotrexate; Middle Aged; Prospective Studies; Recombinant Proteins; Survival Rate; Treatment Outcome; Urologic Neoplasms; Vinblastine | 2002 |
C-erbB-2 expression does not predict response to docetaxel or sequential methotrexate and 5-fluorouracil in advanced breast cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Docetaxel; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Proteins; Neoplasm Staging; Paclitaxel; Predictive Value of Tests; Receptor, ErbB-2; Taxoids | 2002 |
The predictive value of bcl-2, bax, bcl-xL, bag-1, fas, and fasL for chemotherapy response in advanced breast cancer.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; bcl-2-Associated X Protein; bcl-X Protein; Breast Neoplasms; Carrier Proteins; DNA-Binding Proteins; Drug Resistance, Neoplasm; Fas Ligand Protein; fas Receptor; Female; Fluorouracil; Humans; Immunoenzyme Techniques; Membrane Glycoproteins; Methotrexate; Middle Aged; Neoplasms, Ductal, Lobular, and Medullary; Prognosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Survival Rate; Transcription Factors | 2002 |
Effect of a 3-hour interval between methotrexate and 5-fluorouracil in the treatment of metastatic colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Injections, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Survival Analysis; Treatment Outcome | 2002 |
Schedule-selective biochemical modulation of 5-fluorouracil in advanced colorectal cancer--a phase II study.
Topics: Abdominal Neoplasms; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Routes; Drug Synergism; Female; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Survival Rate; Treatment Outcome | 2002 |
Physical performance, toxicity, and quality of life as assessed by the physician and the patient.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Diarrhea; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Nausea; Neoplasm Staging; Outcome Assessment, Health Care; Physical Fitness; Quality of Life; Self-Assessment; Surveys and Questionnaires | 2002 |
The feasibility of classical cyclophosphamide, methotrexate, 5-fluorouracil (CMF) for pre- and post-menopausal node-positive breast cancer patients in a Belgian multicentric trial: a study of consistency in relative dose intensity (RDI) and cumulative dos
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Belgium; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Feasibility Studies; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Postmenopause; Premenopause | 2002 |
HER-2 amplification and topoisomerase IIalpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil.
Topics: Aged; Anthracyclines; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Clinical Trials, Phase III as Topic; Cyclophosphamide; Disease-Free Survival; DNA Topoisomerases, Type II; DNA-Binding Proteins; Female; Fluorouracil; Gene Amplification; Humans; In Situ Hybridization, Fluorescence; Lymph Nodes; Methotrexate; Middle Aged; Mutation; Predictive Value of Tests; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Treatment Outcome | 2002 |
The impact of induction duration and the number of high-dose cycles on the long-term survival of women with metastatic breast cancer treated with high-dose chemotherapy with stem cell rescue: an analysis of sequential phase I/II trials from the Dana-Farbe
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Estrogens; Female; Fluorouracil; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Life Tables; Melphalan; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Paclitaxel; Peripheral Blood Stem Cell Transplantation; Progesterone; Prognosis; Proportional Hazards Models; Remission Induction; Survival Analysis; Thiotepa; Time Factors; Treatment Outcome | 2002 |
Changes in microvessel density as assessed by CD34 antibodies after primary chemotherapy in human breast cancer.
Topics: Adult; Aged; Antibodies, Monoclonal; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Immunoenzyme Techniques; Ki-67 Antigen; Methotrexate; Microcirculation; Middle Aged; Neoplasm Staging; Neovascularization, Pathologic; Proto-Oncogene Proteins c-bcl-2; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Rate; Tamoxifen; Tumor Suppressor Protein p53 | 2002 |
Tumour microvessel density as predictor of chemotherapy response in breast cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease Progression; Disease-Free Survival; Docetaxel; Female; Fluorouracil; Humans; Methotrexate; Neovascularization, Pathologic; Paclitaxel; Prognosis; Taxoids; Time Factors; Treatment Outcome | 2002 |
Duration of adjuvant chemotherapy for breast cancer: a joint analysis of two randomised trials investigating three versus six courses of CMF.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Premenopause; Survival Rate; Time Factors | 2002 |
Endocrine responsiveness and tailoring adjuvant therapy for postmenopausal lymph node-negative breast cancer: a randomized trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Endocrine System; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Postmenopause; Quality of Life; Tamoxifen; Time Factors; Treatment Outcome | 2002 |
Addition of either irinotecan or methotrexate to bolus 5-fluorouracil and high-dose folinic acid every 2 weeks in advanced colorectal carcinoma: a randomised study by the Southern Italy Cooperative Oncology Group.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Camptothecin; Colorectal Neoplasms; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Italy; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Remission Induction; Survival Analysis; Treatment Outcome | 2002 |
Randomized trial comparing cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) with rotational CMF, epirubicin and vincristine as primary chemotherapy in operable breast carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Logistic Models; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Multivariate Analysis; Prospective Studies; Vincristine | 2002 |
Weight gain in women with breast cancer treated with adjuvant cyclophosphomide, methotrexate and 5-fluorouracil. Analysis of resting energy expenditure and body composition.
Topics: Antineoplastic Combined Chemotherapy Protocols; Body Composition; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Energy Metabolism; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Patient Selection; Weight Gain | 2002 |
Neoadjuvant chemotherapy with sequential methotrexate and 5-fluorouracil scheduling, epirubicin and cisplatin for locally advanced bladder cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Epirubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Treatment Outcome; Urinary Bladder Neoplasms | 2002 |
Late effects of adjuvant chemotherapy on cognitive function: a follow-up study in breast cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cognition Disorders; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Mastectomy; Mental Processes; Methotrexate; Middle Aged; Neoplasm Staging; Netherlands; Neuropsychological Tests; Predictive Value of Tests; Probability; Reference Values; Risk Assessment; Severity of Illness Index; Survival Analysis; Time Factors | 2002 |
Pathologic changes related to CMF primary chemotherapy in breast cancer. Pathological evaluation of response predicts clinical outcome.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Cyclophosphamide; Disease-Free Survival; Female; Fibrosis; Fluorouracil; Humans; Lymph Node Excision; Lymphatic Metastasis; Mammography; Methotrexate; Middle Aged; Neoplasm Staging; Remission Induction; Survival Rate | 2002 |
Second-line chemotherapy with a hybrid-alternating regimen of bolus 5FU modulated by methotrexate and infusional 5FU modulated by folinic acid in patients with metastatic colorectal cancer pretreated with 5FU. A phase 2 study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Diarrhea; Disease Progression; Fluorouracil; Follow-Up Studies; Humans; Infusions, Intravenous; Injections, Intravenous; Leucovorin; Methotrexate; Middle Aged; Nausea; Neoplasm Staging; Survival Rate; Treatment Outcome; Vomiting | 2002 |
CMF (cyclophosphamide, methotrexate, 5-fluorouracil) versus CNF (cyclophosphamide, mitoxantrone, 5-fluorouracil) as adjuvant chemotherapy for stage II lymph-node positive breast cancer: results by demographic and clinical subgroups.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Fluorouracil; Humans; Jews; Lymphatic Metastasis; Methotrexate; Mitoxantrone; Survival Analysis | 2002 |
Role of LHRH agonists in premenopausal women with oestrogen receptor-positive breast cancer: the ZEBRA experience.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Gonadotropin-Releasing Hormone; Goserelin; Humans; Methotrexate; Middle Aged; Postmenopause; Quality of Life; Receptors, Estrogen | 2002 |
Epirubicin versus CMF as adjuvant therapy for stage I and II breast cancer: a prospective randomised study.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Prospective Studies | 2002 |
Block sequential adriamycin CMF--optimal non-myeloablative chemotherapy for high risk adjuvant breast cancer?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Risk Factors; Survival Rate; Treatment Outcome | 2002 |
Randomized adjuvant trial of tamoxifen and goserelin versus cyclophosphamide, methotrexate, and fluorouracil: evidence for the superiority of treatment with endocrine blockade in premenopausal patients with hormone-responsive breast cancer--Austrian Breas
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Goserelin; Humans; Methotrexate; Neoplasm Recurrence, Local; Ovariectomy; Premenopause; Survival Rate; Tamoxifen | 2002 |
Adjuvant chemotherapy with cyclophosphamide, methotrexate, and 5-fluorouracil, vincristine, and prednisone compared with single-agent L-phenylalanine mustard for patients with operable breast carcinoma and positive axillary lymph nodes: 20-year results of
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Mastectomy, Modified Radical; Mastectomy, Radical; Melphalan; Menopause; Methotrexate; Middle Aged; Prednisone; Survival Rate; Vincristine | 2003 |
HER2 overexpression and doxorubicin in adjuvant chemotherapy for resectable breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Methotrexate; Middle Aged; Predictive Value of Tests; Prognosis; Receptor, ErbB-2; Survival | 2003 |
Accelerated versus standard cyclophosphamide, epirubicin and 5-fluorouracil or cyclophosphamide, methotrexate and 5-fluorouracil: a randomized phase III trial in locally advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lymph Node Excision; Mastectomy; Methotrexate; Middle Aged; Tamoxifen; Treatment Outcome | 2003 |
High-dose 5-fluorouracil plus low dose methotrexate plus or minus low-dose PALA in advanced colorectal cancer: a randomised phase II-III trial of the EORTC Gastrointestinal Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Phosphonoacetic Acid; Survival Analysis; Treatment Outcome | 2003 |
[Study on effect of moxibustion and guben yiliu III combined with chemotherapy in treating middle-late stage malignant tumor].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Drugs, Chinese Herbal; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Moxibustion; Phytotherapy | 2001 |
Etoposide, doxorubicin and cisplatin alternating with 5-fluorouracil, doxorubicin and high-dose methotrexate in patients with advanced adenocarcinoma of the stomach or the gastroesophageal junction.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Etoposide; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Stomach Neoplasms; Treatment Outcome | 2002 |
Continuing chemotherapy or not after the induction treatment in advanced breast cancer patients. clinical outcomes and oncologists' preferences.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Decision Making; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Practice Patterns, Physicians'; Risk Factors; Survival Analysis | 2003 |
Vinorelbine, methotrexate and fluorouracil (VMF) as first-line therapy in metastatic breast cancer: a randomized phase II trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chi-Square Distribution; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Statistics, Nonparametric; Survival Rate; Vinblastine; Vinorelbine | 2003 |
Natural history of more than 20 years of node-positive primary breast carcinoma treated with cyclophosphamide, methotrexate, and fluorouracil-based adjuvant chemotherapy: a study by the Cancer and Leukemia Group B.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cause of Death; Chemotherapy, Adjuvant; Cyclophosphamide; Disease Progression; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prednisone; Vincristine | 2003 |
Side effects of adjuvant endocrine treatment in premenopausal breast cancer patients: a prospective randomized study.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Depression; Female; Fluorouracil; Goserelin; Health Status; Humans; Methotrexate; Middle Aged; Premenopause; Severity of Illness Index; Tamoxifen; Treatment Outcome | 2003 |
Acute toxicity of concurrent adjuvant radiotherapy and chemotherapy (CMF or AC) in breast cancer patients. a prospective, comparative, non-randomised study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Hospitalization; Humans; Mastectomy, Radical; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Radiotherapy, Adjuvant; Risk Factors | 2003 |
A phase III trial of sequential adjuvant chemotherapy for operable breast carcinoma: final analysis with 10-year follow-up.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Receptors, Estrogen; Tamoxifen; Vinblastine | 2003 |
Randomised trial: One cycle of anthracycline-containing adjuvant chemotherapy compared with six cycles of CMF treatment in node-positive, hormone receptor-negative breast cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Staging; Receptors, Estrogen; Receptors, Progesterone; Survival Rate; Vincristine | 2003 |
Doxorubicin in combination with fluorouracil and cyclophosphamide (i.v. FAC regimen, day 1, 21) versus methotrexate in combination with fluorouracil and cyclophosphamide (i.v. CMF regimen, day 1, 21) as adjuvant chemotherapy for operable breast cancer: a
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Humans; Infusions, Intravenous; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Prospective Studies; Survival Rate; Treatment Outcome | 2003 |
Brachytherapy boost to the tumour bed in high risk patients after limited surgery for breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Mastectomy; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Patient Satisfaction; Prognosis; Risk Factors; Salvage Therapy; Treatment Outcome | 2003 |
Prognostic value of quality of life scores for time to progression (TTP) and overall survival time (OS) in advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cross-Over Studies; Disease Progression; Docetaxel; Female; Fluorouracil; Humans; Methotrexate; Paclitaxel; Prognosis; Quality of Life; Statistics as Topic; Survival Analysis; Taxoids | 2003 |
Cisplatin, epirubicin, leucovorin and 5-fluorouracil (PELF) is more active than 5-fluorouracil, doxorubicin and methotrexate (FAMTX) in advanced gastric carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Confidence Intervals; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Italy; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Probability; Prognosis; Stomach Neoplasms; Survival Analysis; Treatment Outcome | 2003 |
Survival analyses from the ZEBRA study. goserelin (Zoladex) versus CMF in premenopausal women with node-positive breast cancer.
Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Goserelin; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Premenopause; Receptors, Estrogen; Risk Factors; Survival Analysis; Treatment Outcome | 2003 |
Pretreatment haemoglobin levels significantly predict the tumour response to primary chemotherapy in human breast cancer.
Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cyclophosphamide; Epirubicin; Erythrocyte Count; Female; Fluorouracil; Hemoglobins; Humans; Immunoenzyme Techniques; Ki-67 Antigen; Methotrexate; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Treatment Outcome; Tumor Suppressor Protein p53 | 2003 |
Upregulation of HER-2/neu by ovarian ablation: results of a randomized trial comparing leuprorelin to CMF as adjuvant therapy in node-positive breast cancer patients.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Humans; Immunohistochemistry; Infusions, Intravenous; Leuprolide; Methotrexate; Middle Aged; Ovary; Receptor, ErbB-2; Treatment Outcome; Up-Regulation | 2003 |
Bone mineral density in premenopausal women treated for node-positive early breast cancer with 2 years of goserelin or 6 months of cyclophosphamide, methotrexate and 5-fluorouracil (CMF).
Topics: Adult; Amenorrhea; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Density; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Female; Femur Neck; Fluorouracil; Goserelin; Humans; Lumbar Vertebrae; Methotrexate; Premenopause | 2003 |
[The modern organ- and function-sparing surgical treatment in oncology].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma in Situ; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Electrosurgery; Endometrial Neoplasms; Estrogen Receptor Modulators; Female; Fluorouracil; Humans; Hysterectomy; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Ovarian Neoplasms; Postoperative Care; Progestins; Prognosis; Prospective Studies; Radiotherapy Dosage; Risk Factors; Survival Analysis; Time Factors; Uterine Cervical Neoplasms | 2003 |
Quality of life in goserelin-treated versus cyclophosphamide + methotrexate + fluorouracil-treated premenopausal and perimenopausal patients with node-positive, early breast cancer: the Zoladex Early Breast Cancer Research Association Trialists Group.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Climacteric; Cyclophosphamide; Factor Analysis, Statistical; Female; Fluorouracil; Goserelin; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Premenopause; Quality of Life; Surveys and Questionnaires | 2003 |
Adjuvant chemotherapy followed by goserelin versus either modality alone for premenopausal lymph node-negative breast cancer: a randomized trial.
Topics: Adult; Amenorrhea; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Confidence Intervals; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Goserelin; Humans; Incidence; Lymphatic Metastasis; Methotrexate; Middle Aged; Premenopause; Receptors, Estrogen; Survival Analysis; Treatment Outcome | 2003 |
Improved survival in patients with peritoneal metastases from colorectal cancer: a preliminary study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged; Peritoneal Neoplasms; Prognosis; Survival Analysis; Treatment Outcome | 2004 |
A prospective study of concurrent cyclophosphamide/methotrexate/5-fluorouracil and reduced-dose radiotherapy in patients with early-stage breast carcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Radiation Dosage; Risk Factors; Survival Analysis; Treatment Outcome | 2004 |
[Radiation and concomitant chemotherapy after surgery for breast cancer].
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pilot Projects; Postoperative Care; Radiotherapy Dosage; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Time Factors | 2004 |
Clinical relevance of different sequencing of doxorubicin and cyclophosphamide, methotrexate, and Fluorouracil in operable breast cancer.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Infusions, Intravenous; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Odds Ratio; Risk Factors; Treatment Outcome | 2004 |
Concurrent and adjuvant chemotherapy for nasopharyngeal carcinoma: a factorial study.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Tegafur; Treatment Outcome; Uracil; Vincristine | 2004 |
Mutation and accumulation of p53 related to results of adjuvant therapy of postmenopausal breast cancer patients.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Genes, p53; Humans; Methotrexate; Mutation; Neoplasm Metastasis; Neoplasm Recurrence, Local; Postmenopause; Radiotherapy, Adjuvant; Tamoxifen; Treatment Outcome; Tumor Suppressor Protein p53 | 2004 |
Neo-adjuvant chemotherapy for operable gastric cancer: long term results of the Dutch randomised FAMTX trial.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Doxorubicin; Fluorouracil; Gastrectomy; Humans; Methotrexate; Neoadjuvant Therapy; Neoplasm Staging; Stomach Neoplasms; Survival Analysis; Treatment Outcome | 2004 |
Conventional adjuvant chemotherapy versus single-cycle, autograft-supported, high-dose, late-intensification chemotherapy in high-risk breast cancer patients: a randomized trial.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Female; Filgrastim; Fluorouracil; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Leukapheresis; Lymphatic Metastasis; Mastectomy; Mastectomy, Segmental; Methotrexate; Middle Aged; Prospective Studies; Radiotherapy, Adjuvant; Recombinant Proteins; Risk Assessment; Risk Factors; Survival Analysis; Transplantation, Autologous; Treatment Outcome | 2004 |
Tamoxifen treatment reverses the adverse effects of chemotherapy-induced ovarian failure on serum lipids.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Clodronic Acid; Cyclophosphamide; Female; Fluorouracil; Humans; Lipoproteins; Methotrexate; Middle Aged; Premenopause; Primary Ovarian Insufficiency; Receptors, Estrogen; Tamoxifen | 2004 |
Health-related quality of life in axillary node-negative, estrogen receptor-negative breast cancer patients undergoing AC versus CMF chemotherapy: findings from the National Surgical Adjuvant Breast and Bowel Project B-23.
Topics: Activities of Daily Living; Administration, Oral; Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Health Status; Humans; Infusions, Intravenous; Methotrexate; Middle Aged; Placebos; Quality of Life; Receptors, Estrogen; Tamoxifen | 2004 |
Phase II study of sequential methotrexate and 5-fluorouracil chemotherapy against peritoneally disseminated gastric cancer with malignant ascites: a report from the Gastrointestinal Oncology Study Group of the Japan Clinical Oncology Group, JCOG 9603 Tria
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascites; Drug Administration Schedule; Female; Fluorouracil; Humans; Japan; Leucovorin; Male; Methotrexate; Middle Aged; Peritoneal Neoplasms; Stomach Neoplasms; Survival Rate | 2004 |
1-hexylcarbamoyl-5-fluorouracil + cyclophosphamide + tamoxifen versus CMF + tamoxifen in women with lymph node-positive breast cancer after primary surgery: a randomized controlled trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Survival Rate; Tamoxifen | 2004 |
Short-term intermittent intravenous clodronate in the prevention of bone loss related to chemotherapy-induced ovarian failure.
Topics: Adult; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Bone Resorption; Breast Neoplasms; Chemotherapy, Adjuvant; Clodronic Acid; Cyclophosphamide; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Infusions, Intravenous; Methotrexate; Middle Aged; Premenopause; Primary Ovarian Insufficiency | 2004 |
Phase II study of a triplet regimen in advanced colorectal cancer using methotrexate, oxaliplatin and 5-fluorouracil.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Peritoneal Neoplasms; Treatment Outcome | 2004 |
Patterns of locoregional failure in patients with operable breast cancer treated by mastectomy and adjuvant chemotherapy with or without tamoxifen and without radiotherapy: results from five National Surgical Adjuvant Breast and Bowel Project randomized c
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Proportional Hazards Models; Statistics, Nonparametric; Survival Analysis; Tamoxifen; Treatment Outcome | 2004 |
Quantifying trade-offs: quality of life and quality-adjusted survival in a randomised trial of chemotherapy in postmenopausal patients with lymph node-negative breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Nodes; Male; Methotrexate; Middle Aged; Neoplasm Staging; Postmenopause; Quality of Life; Receptors, Estrogen; Survival Rate; Tamoxifen | 2004 |
Treatment of axillary lymph node-negative, estrogen receptor-negative breast cancer: updated findings from National Surgical Adjuvant Breast and Bowel Project clinical trials.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Proportional Hazards Models; Receptors, Estrogen; Survival Analysis; Treatment Outcome | 2004 |
Adjuvant sequential methotrexate --> 5-fluorouracil vs 5-fluorouracil plus leucovorin in radically resected stage III and high-risk stage II colon cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Survival Rate | 2005 |
Preradiation chemotherapy with methotrexate, cisplatin, 5-fluorouracil, and leucovorin for pediatric nasopharyngeal carcinoma.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Combined Modality Therapy; Epstein-Barr Virus Infections; Fluorouracil; Herpesvirus 4, Human; Humans; Leucovorin; Methotrexate; Nasopharyngeal Neoplasms; Survival Rate | 2005 |
Primary chemotherapy with cyclophosphamide, methotrexate, and 5-fluorouracil in operable breast carcinoma.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Treatment Outcome | 2005 |
Locoregional radiation therapy in patients with high-risk breast cancer receiving adjuvant chemotherapy: 20-year results of the British Columbia randomized trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; British Columbia; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Lymphatic Metastasis; Mastectomy, Modified Radical; Methotrexate; Neoplasm Recurrence, Local; Proportional Hazards Models; Radiotherapy, Adjuvant; Risk Assessment; Survival Analysis; Treatment Outcome | 2005 |
A randomised factorial trial of sequential doxorubicin and CMF vs CMF and chemotherapy alone vs chemotherapy followed by goserelin plus tamoxifen as adjuvant treatment of node-positive breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Goserelin; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Tamoxifen | 2005 |
Sequencing of chemotherapy and radiation therapy in early-stage breast cancer: updated results of a prospective randomized trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy, Segmental; Methotrexate; Middle Aged; Time Factors | 2005 |
Timing of CMF chemotherapy in combination with tamoxifen in postmenopausal women with breast cancer: role of endocrine responsiveness of the tumor.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Confidence Intervals; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Postmenopause; Probability; Prognosis; Reference Values; Risk Assessment; Survival Rate; Tamoxifen; Time Factors; Treatment Outcome | 2005 |
Adjuvant chemotherapy for elderly patients (> or =70 years) with early high-risk breast cancer: a retrospective analysis of 260 patients.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Nodes; Methotrexate; Middle Aged; Neoplasm Staging; Postmenopause; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Risk Factors; Survival Rate | 2005 |
Breast cancer recurrence dynamics following adjuvant CMF is consistent with tumor dormancy and mastectomy-driven acceleration of the metastatic process.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Fluorouracil; Humans; Mastectomy; Methotrexate; Neoplasm Metastasis; Recurrence | 2005 |
Primary chemotherapy in operable breast carcinoma comparing CMF (cyclophosphamide, methotrexate, 5-fluorouracil) with an anthracycline-containing regimen: short-term responses translated into long-term outcomes.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Epirubicin; Fluorouracil; Humans; Methotrexate; Treatment Outcome; Vincristine | 2005 |
Preoperative second-line chemotherapy induces objective responses in primary breast cancer.
Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Docetaxel; Epirubicin; Female; Fluorouracil; Humans; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoadjuvant Therapy; Paclitaxel; Preoperative Care; Taxoids; Treatment Failure; Treatment Outcome | 2005 |
Thermo-chemo-radiotherapy for advanced bile duct carcinoma.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Hyperthermia, Induced; Male; Methotrexate; Middle Aged | 2005 |
'Atrophic telogen effluvium' from cytotoxic drugs and a randomized controlled trial to investigate the possible protective effect of pretreatment with a topical vitamin D analogue in humans.
Topics: Administration, Topical; Adult; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Calcitriol; Cyclophosphamide; Dermatologic Agents; Double-Blind Method; Female; Fluorouracil; Hair; Humans; Methotrexate; Middle Aged; Prospective Studies | 2005 |
Randomized trial comparing cyclophosphamide, epirubicin, and fluorouracil with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer: update of National Cancer Institute of Canada Clinical Trials Group Tr
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Infusions, Intravenous; Methotrexate; Middle Aged; Premenopause | 2005 |
Three-year oral clodronate treatment does not impair mineralization of newly formed bone--a histomorphometric study.
Topics: Administration, Oral; Adult; Aged; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Calcification, Physiologic; Chemotherapy, Adjuvant; Clodronic Acid; Cyclophosphamide; Female; Fluorouracil; Humans; Ilium; Methotrexate; Middle Aged | 2005 |
Cyclin A as a marker for prognosis and chemotherapy response in advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal; Carcinoma, Lobular; Cyclin A; Fluorouracil; Humans; Immunoenzyme Techniques; Methotrexate; Prognosis | 2005 |
Bendamustine prolongs progression-free survival in metastatic breast cancer (MBC): a phase III prospective, randomized, multicenter trial of bendamustine hydrochloride, methotrexate and 5-fluorouracil (BMF) versus cyclophosphamide, methotrexate and 5-fluo
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Nitrogen Mustard Compounds; Prospective Studies; Survival Rate; Time Factors; Treatment Outcome | 2005 |
Patients' preferences for adjuvant chemotherapy in early breast cancer: what makes AC and CMF worthwhile now?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Life Expectancy; Methotrexate; Middle Aged; Neoadjuvant Therapy; Patient Satisfaction; Prognosis; Risk Factors; Surveys and Questionnaires; Survival Rate | 2005 |
Does timing of adjuvant chemotherapy influence the prognosis after early breast cancer? Results of the Danish Breast Cancer Cooperative Group (DBCG).
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Stereoisomerism; Survival Rate; Time Factors | 2005 |
Postoperative dose-dense sequential chemotherapy with epirubicin, followed by CMF with or without paclitaxel, in patients with high-risk operable breast cancer: a randomized phase III study conducted by the Hellenic Cooperative Oncology Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Paclitaxel; Risk Factors; Survival Rate; Treatment Outcome | 2005 |
Evaluation of toxicities induced by chemotherapy in breast cancer patients.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Breast Neoplasms; Cisplatin; Cohort Studies; Drug Evaluation; Drug Therapy, Combination; Erythrocyte Count; Erythrocytes; Female; Fluorouracil; Humans; L-Lactate Dehydrogenase; Leukocyte Count; Leukocytes; Leukopenia; Methotrexate; Middle Aged; Pakistan; Platelet Count; Tamoxifen; Thrombocytopenia | 2005 |
Prognostic value of extracapsular tumor spread for locoregional control in premenopausal patients with node-positive breast cancer treated with classical cyclophosphamide, methotrexate, and fluorouracil: long-term observations from International Breast Ca
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Postmenopause; Prognosis; Retrospective Studies | 2005 |
Benefits of axillary radiotherapy unclear in women with early stage breast cancer undergoing conservative breast surgery without axillary dissection.
Topics: Antineoplastic Agents; Axilla; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Mastectomy, Segmental; Methotrexate; Neoplasm Recurrence, Local; Tamoxifen | 2005 |
A phase III randomized study on the sequencing of radiotherapy and chemotherapy in the conservative management of early-stage breast cancer.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymph Node Excision; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy, Adjuvant; Tamoxifen | 2006 |
retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danis
Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; DNA Topoisomerases, Type II; DNA-Binding Proteins; Epirubicin; Female; Fluorouracil; Gene Amplification; Gene Deletion; Humans; In Situ Hybridization, Fluorescence; Isoenzymes; Methotrexate; Poly-ADP-Ribose Binding Proteins; Predictive Value of Tests; Premenopause; Receptor, ErbB-2; Retrospective Studies; Stereoisomerism; Treatment Outcome | 2005 |
Tamoxifen versus control after adjuvant, risk-adapted chemotherapy in postmenopausal, receptor-negative patients with breast cancer: a randomized trial (GABG-IV D-93)--the German Adjuvant Breast Cancer Group.
Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Germany; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Postmenopause; Receptors, Estrogen; Risk Factors; Survival Rate; Tamoxifen; Treatment Outcome | 2005 |
A comparison of the outcomes of non-randomised chemotherapy regimens in node positive breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Survival Analysis; Treatment Outcome | 2005 |
Randomized, controlled trial of cyclophosphamide, methotrexate, and fluorouracil versus cyclophosphamide, doxorubicin, and fluorouracil with and without tamoxifen for high-risk, node-negative breast cancer: treatment results of Intergroup Protocol INT-010
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Proportional Hazards Models; Prospective Studies; Survival Analysis; Tamoxifen | 2005 |
Long-term follow-up of a randomised trial designed to determine the need for irradiation following conservative surgery for the treatment of invasive breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Mastectomy, Segmental; Methotrexate; Middle Aged; Receptors, Estrogen; Recurrence | 2006 |
[A randomized crossover study of ramosetron plus dexamethasone for the prevention of nausea and vomiting induced by chemotherapy including cisplatin-comparison of ramosetron combined with 8 mg and 12 mg of dexamethasone].
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma, Squamous Cell; Cisplatin; Cross-Over Studies; Dexamethasone; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Nausea; Vomiting, Anticipatory | 2005 |
Feasibility and tolerability of sequential doxorubicin/paclitaxel followed by cyclophosphamide, methotrexate, and fluorouracil and its effects on tumor response as preoperative therapy.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Multivariate Analysis; Paclitaxel; Preoperative Care; Treatment Outcome | 2005 |
Gonadotropin-releasing hormone analogues added to adjuvant chemotherapy protect ovarian function and improve clinical outcomes in young women with early breast carcinoma.
Topics: Adult; Age of Onset; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Estrogen Receptor Modulators; Female; Fluorouracil; Gonadotropin-Releasing Hormone; Humans; Infertility, Female; Methotrexate; Middle Aged; Ovary; Pregnancy; Pregnancy Outcome; Premenopause; Retrospective Studies; Treatment Outcome | 2006 |
Prognostic index score and clinical prediction model of local regional recurrence after mastectomy in breast cancer patients.
Topics: Adult; Aged; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Axilla; Bayes Theorem; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy, Modified Radical; Methotrexate; Middle Aged; Models, Biological; Multivariate Analysis; Neoplasm Recurrence, Local; Prognosis; Proportional Hazards Models; Receptors, Estrogen | 2006 |
Chemotherapy versus ovarian ablation as adjuvant therapy for breast cancer: impact on health-related quality of life in a randomized trial.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovary; Quality of Life; Recurrence; Surveys and Questionnaires; Time Factors; Treatment Outcome | 2006 |
Study of failure pattern among high-risk breast cancer patients with or without postmastectomy radiotherapy in addition to adjuvant systemic therapy: long-term results from the Danish Breast Cancer Cooperative Group DBCG 82 b and c randomized studies.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Node Excision; Mastectomy; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Radiotherapy, Adjuvant; Risk; Tamoxifen; Treatment Failure | 2006 |
CMF with 5-FU in continuous infusion--a pilot study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusion Pumps; Methotrexate; Middle Aged; Pilot Projects | 2006 |
Randomised trial: survival benefit and safety of adjuvant dose-dense chemotherapy for node-positive breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Epirubicin; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Lymphatic Metastasis; Mastectomy, Segmental; Methotrexate; Middle Aged; Paclitaxel; Prognosis | 2006 |
A randomized phase III comparative trial of immediate consolidation with high-dose chemotherapy and autologous peripheral blood progenitor cell support compared to observation with delayed consolidation in women with metastatic breast cancer and only bone
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Combined Modality Therapy; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Peripheral Blood Stem Cell Transplantation; Prognosis; Prospective Studies; Survival Rate; Time Factors; Transplantation, Autologous | 2006 |
HER2 and responsiveness of breast cancer to adjuvant chemotherapy.
Topics: Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Gene Amplification; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Humans; Methotrexate; Middle Aged; Premenopause; Prognosis; Receptor, ErbB-2; Survival Analysis | 2006 |
CMF versus goserelin as adjuvant therapy for node-negative, hormone-receptor-positive breast cancer in premenopausal patients: a randomised trial (GABG trial IV-A-93).
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Goserelin; Humans; Methotrexate; Middle Aged; Patient Compliance; Premenopause; Treatment Outcome | 2006 |
Paclitaxel and epirubicin followed by cyclophosphamide, methotrexate and 5-fluorouracil for patients with stage IIIC breast cancer with ten or more involved axillary lymph nodes.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Paclitaxel; Survival Analysis | 2006 |
A phase II study of combined chemotherapy with methotrexate, 5-fluorouracil, and low-dose cisplatin (MFP) for histologically diffuse-type advanced and recurrent gastric cancer (KDOG9501).
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Pleural Effusion, Malignant; Stomach Neoplasms; Survival Analysis; Treatment Outcome | 2006 |
Evaluation of the prognostic and predictive value of p53 and Bcl-2 in breast cancer patients participating in a randomized study with dose-dense sequential adjuvant chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Cyclophosphamide; Dose-Response Relationship, Drug; Epirubicin; Female; Fluorouracil; Gene Expression; Humans; Methotrexate; Middle Aged; Molecular Diagnostic Techniques; Paclitaxel; Predictive Value of Tests; Prognosis; Proto-Oncogene Proteins c-bcl-2; Survival Analysis; Tumor Suppressor Protein p53 | 2006 |
Thirty-year follow-up of chemo/hormonal therapy in node-positive breast cancer.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Estrogen Receptor Modulators; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy, Segmental; Methotrexate; Postmenopause; Premenopause; Receptors, Estrogen; Survival Analysis; Tamoxifen | 2007 |
Analysis of efficacy and toxicity of chemotherapy with cisplatin, 5-fluorouracil, methotrexate and leucovorin (PFML) and radiotherapy in the treatment of locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Mucositis; Neutropenia; Radiotherapy Dosage | 2007 |
Similar efficacy for ovarian ablation compared with cyclophosphamide, methotrexate, and fluorouracil: from a randomized comparison of premenopausal patients with node-positive, hormone receptor-positive breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Odds Ratio; Ovary; Premenopause; Radiotherapy, Adjuvant; Survival Analysis | 2006 |
Epirubicin and cyclophosphamide, methotrexate, and fluorouracil as adjuvant therapy for early breast cancer.
Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Quality of Life; Recurrence; Survival Analysis | 2006 |
Capecitabine/Cyclophosphamide/Methotrexate for patients with metastatic breast cancer: a dose-finding, feasibility, and efficacy study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Carcinoma; Cyclophosphamide; Deoxycytidine; Feasibility Studies; Female; Fluorouracil; Humans; Maximum Tolerated Dose; Methotrexate; Middle Aged; Neoplasm Metastasis; Prodrugs; Survival Analysis; Treatment Outcome | 2006 |
Effect of age and radiation dose on local control after breast conserving treatment: EORTC trial 22881-10882.
Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Radiation; Female; Fluorouracil; Humans; Mastectomy, Segmental; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Proportional Hazards Models; Radiotherapy; Radiotherapy Dosage; Risk | 2007 |
Adjuvant chemotherapy followed by goserelin compared with either modality alone: the impact on amenorrhea, hot flashes, and quality of life in premenopausal patients--the International Breast Cancer Study Group Trial VIII.
Topics: Adult; Age Factors; Amenorrhea; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Goserelin; Hot Flashes; Humans; Methotrexate; Middle Aged; Premenopause; Quality of Life; Treatment Outcome | 2007 |
Adjuvant dose-dense sequential chemotherapy with epirubicin, CMF, and weekly docetaxel is feasible and safe in patients with operable breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Docetaxel; Dose-Response Relationship, Drug; Epirubicin; Feasibility Studies; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Taxoids | 2006 |
Is the benefit of postmastectomy irradiation limited to patients with four or more positive nodes, as recommended in international consensus reports? A subgroup analysis of the DBCG 82 b&c randomized trials.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Postoperative Care; Prognosis; Survival Rate; Tamoxifen | 2007 |
Improved outcome from substituting methotrexate with epirubicin: results from a randomised comparison of CMF versus CEF in patients with primary breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Cytarabine; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Treatment Outcome | 2007 |
The ratio of positive to excised nodes identifies high-risk subsets and reduces inter-institutional differences in locoregional recurrence risk estimates in breast cancer patients with 1-3 positive nodes: an analysis of prospective data from British Colum
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastectomy, Modified Radical; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Regression Analysis | 2007 |
Polychemotherapy for early breast cancer: results from the international adjuvant breast cancer chemotherapy randomized trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Postmenopause; Quality of Life; Receptors, Estrogen; Research Design; Surveys and Questionnaires; Survival Analysis | 2007 |
Effects of a treatment gap during adjuvant chemotherapy in node-positive breast cancer: results of International Breast Cancer Study Group (IBCSG) Trials 13-93 and 14-93.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Receptors, Estrogen; Tamoxifen | 2007 |
Amplification of CCND1 and PAK1 as predictors of recurrence and tamoxifen resistance in postmenopausal breast cancer.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclin D; Cyclins; Cyclophosphamide; Drug Resistance, Neoplasm; Female; Fluorouracil; Gene Amplification; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; p21-Activated Kinases; Postmenopause; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tamoxifen | 2007 |
Age of menopause among women who remain premenopausal following treatment for early breast cancer: long-term results from International Breast Cancer Study Group Trials V and VI.
Topics: Adult; Age Factors; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cohort Studies; Cyclophosphamide; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Proportional Hazards Models | 2007 |
Phase III randomized multicenter study on the effects of adjuvant CMF in patients with node-negative, rapidly proliferating breast cancer: twelve-year results and retrospective subgroup analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Proliferation; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Italy; Kaplan-Meier Estimate; Lymph Nodes; Methotrexate; Retrospective Studies; Time Factors; Treatment Outcome | 2008 |
Leuprorelin acetate every-3-months depot versus cyclophosphamide, methotrexate, and fluorouracil as adjuvant treatment in premenopausal patients with node-positive breast cancer: the TABLE study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Germany; Humans; Leuprolide; Lymphatic Metastasis; Methotrexate; Neoplasm Recurrence, Local; Perimenopause; Premenopause; Survival Rate; Treatment Outcome; Ukraine | 2007 |
Anemia during adjuvant non-taxane chemotherapy for early breast cancer: Incidence and risk factors from two trials of the International Breast Cancer Study Group.
Topics: Adult; Age Factors; Anemia; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Hemoglobins; Humans; Incidence; Leukocytes; Lymphatic Metastasis; Methotrexate; Middle Aged; Regression Analysis; Risk Factors; Severity of Illness Index; Time Factors | 2008 |
Postoperative dose-dense sequential chemotherapy with epirubicin, paclitaxel and CMF in patients with high-risk breast cancer: safety analysis of the Hellenic Cooperative Oncology Group randomized phase III trial HE 10/00.
Topics: Adult; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Epirubicin; Estrogens; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Neoplasms, Second Primary; Paclitaxel; Peripheral Nervous System Diseases; Tamoxifen | 2008 |
The potential risk of neoadjuvant chemotherapy in breast cancer patients--results from a prospective randomized trial of the Austrian Breast and Colorectal Cancer Study Group (ABCSG-07).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Colorectal Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Medical Oncology; Methotrexate; Middle Aged; Prospective Studies; Risk; Treatment Outcome | 2008 |
Long-term outcome of adjuvant chemotherapy cyclophosphamide, mitoxantrone, and fluorouracil in women with breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitoxantrone; Retrospective Studies; Survival Analysis; Treatment Outcome | 2008 |
Weekly docetaxel versus CMF as adjuvant chemotherapy for elderly breast cancer patients: safety data from the multicentre phase 3 randomised ELDA trial.
Topics: Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Docetaxel; Drug Administration Schedule; Female; Fluorouracil; Hematologic Diseases; Humans; Italy; Methotrexate; Patient Compliance; Taxoids; Treatment Outcome | 2008 |
Triple-negative high-risk breast cancer derives particular benefit from dose intensification of adjuvant chemotherapy: results of WSG AM-01 trial.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Epirubicin; Estrogens; Female; Fluorouracil; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Kaplan-Meier Estimate; Methotrexate; Middle Aged; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Proportional Hazards Models; Retrospective Studies; Single-Blind Method; Survival Analysis; Tamoxifen; Treatment Outcome | 2008 |
Adjuvant chemotherapy with sequential or concurrent anthracycline and docetaxel: Breast International Group 02-98 randomized trial.
Topics: Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Docetaxel; Doxorubicin; Drug Administration Schedule; Estrogen Receptor Modulators; Female; Fluorouracil; Follow-Up Studies; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Odds Ratio; Prospective Studies; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Taxoids; Treatment Outcome | 2008 |
Evaluation of the prognostic and predictive value of HER-1/EGFR in breast cancer patients participating in a randomized study with dose-dense sequential adjuvant chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Genes, erbB-1; Humans; Immunohistochemistry; Methotrexate; Middle Aged; Paclitaxel; Predictive Value of Tests; Prognosis | 2007 |
Concurrent cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy and radiotherapy for early breast carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Comorbidity; Cyclophosphamide; Female; Fluorouracil; Humans; Incidence; Italy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Radiation Injuries; Radiotherapy, Adjuvant; Risk Assessment; Risk Factors; Treatment Outcome | 2008 |
Late cardiac effects of adjuvant chemotherapy in breast cancer survivors treated on Southwest Oncology Group protocol s8897.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Heart; Heart Failure; Humans; Methotrexate; Middle Aged; Prognosis; Receptor, ErbB-2; Survival Rate; Survivors; Tamoxifen; Ventricular Dysfunction, Left | 2008 |
p27 and Skp2 immunoreactivity and its clinical significance with endocrine and chemo-endocrine treatments in node-negative early breast cancer.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Goserelin; Humans; Immunohistochemistry; Methotrexate; Middle Aged; Predictive Value of Tests; Prognosis; Proliferating Cell Nuclear Antigen; S-Phase Kinase-Associated Proteins; Tamoxifen; Treatment Outcome | 2008 |
Fifteen-year median follow-up results after neoadjuvant doxorubicin, followed by mastectomy, followed by adjuvant cyclophosphamide, methotrexate, and fluorouracil (CMF) followed by radiation for stage III breast cancer: a phase II trial (CALGB 8944).
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Disease Progression; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Radiotherapy, Adjuvant; Survival Analysis | 2009 |
[Adjuvant simultaneous mistletoe chemotherapy in breast cancer--influence on immunological parameters, quality of life and tolerability].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Complementary Therapies; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Plant Preparations; Prospective Studies; Quality of Life; Treatment Outcome | 2008 |
Cyclin D1 expression in breast cancer patients receiving adjuvant tamoxifen-based therapy.
Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclin D1; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Goserelin; Humans; Methotrexate; Middle Aged; Prognosis; Receptors, Cytoplasmic and Nuclear; Recurrence; Tamoxifen; Treatment Outcome | 2008 |
Chemoendocrine compared with endocrine adjuvant therapies for node-negative breast cancer: predictive value of centrally reviewed expression of estrogen and progesterone receptors--International Breast Cancer Study Group.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Goserelin; Humans; Immunohistochemistry; Menopause; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Predictive Value of Tests; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Treatment Outcome | 2008 |
Anemia is a significant prognostic factor in local relapse-free survival of premenopausal primary breast cancer patients receiving adjuvant cyclophosphamide/methotrexate/5-fluorouracil chemotherapy.
Topics: Adult; Anemia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Methotrexate; Premenopause; Prognosis; Radiotherapy | 2008 |
Extracapsular tumor spread and the risk of local, axillary and supraclavicular recurrence in node-positive, premenopausal patients with breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Premenopause; Retrospective Studies; Treatment Outcome | 2008 |
Adjuvant cyclophosphamide, methotrexate, and fluorouracil in premonopausal patients with node-positive breast cancer: indirect comparison of dose and schedule in DBCG trials 77, 82, and 89.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Premenopause; Survival Rate | 2008 |
DBCG trial 89B comparing adjuvant CMF and ovarian ablation: similar outcome for eligible but non-enrolled and randomized breast cancer patients.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Ovariectomy; Ovary; Survival Rate; Treatment Outcome | 2008 |
The value of TOP2A gene copy number variation as a biomarker in breast cancer: Update of DBCG trial 89D.
Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; DNA Topoisomerases, Type II; DNA-Binding Proteins; Epirubicin; Female; Fluorouracil; Gene Dosage; Humans; In Situ Hybridization, Fluorescence; Methotrexate; Multivariate Analysis; Poly-ADP-Ribose Binding Proteins; Receptor, ErbB-2; Retrospective Studies | 2008 |
Bisphosphonate treatment in primary breast cancer: results from a randomised comparison of oral pamidronate versus no pamidronate in patients with primary breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Diphosphonates; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Pamidronate | 2008 |
A phase II study of sequential methotrexate and 5-fluorouracil chemotherapy in previously treated gastric cancer: a report from the Gastrointestinal Oncology Group of the Japan Clinical Oncology Group, JCOG 9207 trial.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Drug Administration Schedule; Female; Fluorouracil; Humans; Injections, Intravenous; Japan; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neutropenia; Stomach Neoplasms; Survival Analysis; Treatment Outcome; Vitamin B Complex | 2008 |
Is risk of central nervous system (CNS) relapse related to adjuvant taxane treatment in node-positive breast cancer? Results of the CNS substudy in the intergroup Phase III BIG 02-98 Trial.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Central Nervous System Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Docetaxel; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Taxoids; Treatment Failure | 2008 |
Adjuvant dose-dense sequential chemotherapy with epirubicin, CMF and weekly paclitaxel in patients with resected high-risk breast cancer: a Hellenic Cooperative Oncology Group (HeCOG) study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Administration Schedule; Epirubicin; Feasibility Studies; Female; Fluorouracil; Greece; Humans; Mastectomy; Methotrexate; Middle Aged; Paclitaxel; Radiotherapy, Adjuvant; Risk Assessment; Treatment Outcome | 2008 |
Type 1 receptor tyrosine kinase profiles identify patients with enhanced benefit from anthracyclines in the BR9601 adjuvant breast cancer chemotherapy trial.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; DNA Topoisomerases, Type II; DNA-Binding Proteins; Epirubicin; ErbB Receptors; Female; Fluorouracil; Gene Amplification; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Ki-67 Antigen; Methotrexate; Middle Aged; Patient Selection; Receptor Protein-Tyrosine Kinases; Receptor, ErbB-2; Receptor, ErbB-3; Receptor, ErbB-4; Survival Analysis; Time Factors; Tissue Array Analysis; Treatment Outcome | 2008 |
NEAT: National Epirubicin Adjuvant Trial--toxicity, delivered dose intensity and quality of life.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Disease-Free Survival; Dose-Response Relationship, Drug; Epirubicin; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Methotrexate; Quality of Life | 2008 |
Is adjuvant chemotherapy of benefit for postmenopausal women who receive endocrine treatment for highly endocrine-responsive, node-positive breast cancer? International Breast Cancer Study Group Trials VII and 12-93.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Endocrine System; Female; Fluorouracil; Humans; International Agencies; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Postmenopause; Prognosis; Receptors, Estrogen; Survival Rate; Tamoxifen; Treatment Outcome | 2009 |
Long-term benefit of high-dose epirubicin in adjuvant chemotherapy for node-positive breast cancer: 15-year efficacy results of the Belgian multicentre study.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Belgium; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Humans; Lymph Nodes; Methotrexate; Middle Aged | 2009 |
Adjuvant goserelin and ovarian preservation in chemotherapy treated patients with early breast cancer: results from a randomized trial.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Goserelin; Humans; Methotrexate; Middle Aged; Ovarian Function Tests; Ovary; Premenopause; Primary Ovarian Insufficiency; Tamoxifen | 2009 |
Low-dose capecitabine plus docetaxel as first-line therapy for metastatic breast cancer: phase II results.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Carcinoma; Cyclophosphamide; Deoxycytidine; Disease-Free Survival; Docetaxel; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neutropenia; Paclitaxel; Peripheral Nervous System Diseases; Taxoids; Treatment Outcome | 2009 |
Oral uracil and tegafur compared with classic cyclophosphamide, methotrexate, fluorouracil as postoperative chemotherapy in patients with node-negative, high-risk breast cancer: National Surgical Adjuvant Study for Breast Cancer 01 Trial.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Staging; Quality of Life; Risk Factors; Tegafur; Uracil | 2009 |
Prognostic and predictive impact of central necrosis and fibrosis in early breast cancer: results from two International Breast Cancer Study Group randomized trials of chemoendocrine adjuvant therapy.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fibrosis; Fluorouracil; Goserelin; Humans; Methotrexate; Necrosis; Prognosis; Proportional Hazards Models; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Treatment Outcome | 2010 |
Adjuvant chemotherapy in older women with early-stage breast cancer.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Deoxycytidine; Doxorubicin; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Male; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Receptors, Estrogen; Survival Analysis | 2009 |
Lack of TIMP-1 tumour cell immunoreactivity predicts effect of adjuvant anthracycline-based chemotherapy in patients (n=647) with primary breast cancer. A Danish Breast Cancer Cooperative Group Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Denmark; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Proteins; Tissue Inhibitor of Metalloproteinase-1; Treatment Outcome | 2009 |
Randomized trial of cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, and fluorouracil with node-positive breast cancer in Japan.
Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Adult; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Carcinoma, Papillary; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Japan; Lymphatic Metastasis; Methotrexate; Middle Aged; Receptors, Estrogen; Survival Rate; Treatment Outcome; Young Adult | 2010 |
Adverse prognostic value of peritumoral vascular invasion: is it abrogated by adequate endocrine adjuvant therapy? Results from two International Breast Cancer Study Group randomized trials of chemoendocrine adjuvant therapy for early breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease Progression; Female; Fluorouracil; Goserelin; Humans; Menopause; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neovascularization, Pathologic; Predictive Value of Tests; Prognosis; Treatment Outcome | 2010 |
Uracil-tegafur and tamoxifen vs cyclophosphamide, methotrexate, fluorouracil, and tamoxifen in post-operative adjuvant therapy for stage I, II, or IIIA lymph node-positive breast cancer: a comparative study.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Staging; Survival Rate; Tamoxifen; Tegafur; Uracil | 2009 |
Nitric oxide synthase variants and disease-free survival among treated and untreated breast cancer patients in a Southwest Oncology Group clinical trial.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Medical Oncology; Methotrexate; Middle Aged; Nitric Oxide Synthase Type III; Polymorphism, Genetic; Prognosis; Southwestern United States | 2009 |
Cost analysis comparing an anthracycline/docetaxel regimen to CMF in patients with early stage breast cancer.
Topics: Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Docetaxel; Female; Fluorouracil; Germany; Health Care Costs; Humans; Male; Methotrexate; Middle Aged; Prevalence; Taxoids; Treatment Outcome | 2009 |
Myeloperoxidase genotypes and enhanced efficacy of chemotherapy for early-stage breast cancer in SWOG-8897.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Genotype; Humans; Methotrexate; Middle Aged; Peroxidase; Prognosis; Risk Factors; Tamoxifen; Treatment Outcome | 2009 |
Chemoradiotherapy for locally advanced head and neck cancer: 10-year follow-up of the UK Head and Neck (UKHAN1) trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Malta; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy, Adjuvant; Risk Assessment; Time Factors; Treatment Outcome; Turkey; United Kingdom; Vincristine; Young Adult | 2010 |
Dose-intensified epirubicin versus standard-dose epirubicin/cyclophosphamide followed by CMF in breast cancer patients with 10 or more positive lymph nodes: results of a randomised trial (GABG-IV E-93) - the German Adjuvant Breast Cancer Group.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Epidemiologic Methods; Epirubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Menopause, Premature; Methotrexate; Middle Aged; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Treatment Outcome | 2010 |
Assessment of residual tumour by FDG-PET: conventional imaging and clinical examination following primary chemotherapy of large and locally advanced breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Epirubicin; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Fluorouracil; Humans; Magnetic Resonance Imaging; Mammography; Mastectomy; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm, Residual; Paclitaxel; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Ultrasonography, Mammary | 2010 |
Efficacy of oral tegafur-uracil (UFT) as adjuvant therapy as compared with classical cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) in early breast cancer: a pooled analysis of two randomized controlled trials (N.SAS-BC 01 trial and CUBC trial).
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Receptors, Estrogen; Tegafur; Uracil; Young Adult | 2010 |
Randomized controlled phase II comparison study of concurrent chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil versus CCRT with cisplatin, 5-fluorouracil, methotrexate and leucovorin in patients with locally advanced squamous cell carcinoma
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Endpoint Determination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Survival Analysis; Taxoids; Vitamin B Complex | 2010 |
HER2, TOP2A, and TIMP-1 and responsiveness to adjuvant anthracycline-containing chemotherapy in high-risk breast cancer patients.
Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; DNA Topoisomerases, Type II; DNA-Binding Proteins; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Immunoenzyme Techniques; In Situ Hybridization, Fluorescence; Methotrexate; Neoplasm Staging; Poly-ADP-Ribose Binding Proteins; Prognosis; Receptor, ErbB-2; Retrospective Studies; Risk Factors; Survival Rate; Tissue Array Analysis; Tissue Inhibitor of Metalloproteinase-1; Treatment Outcome | 2010 |
Use of pegfilgrastim support on day 9 to maintain relative dose intensity of chemotherapy in breast cancer patients receiving a day 1 and 8 CMF regimen.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma; Chemotherapy, Adjuvant; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Filgrastim; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Injections, Intravenous; Male; Methotrexate; Middle Aged; Neutropenia; Polyethylene Glycols; Recombinant Proteins; Treatment Outcome | 2009 |
Phase 2 trial of primary systemic therapy with doxorubicin and docetaxel followed by surgery, radiotherapy, and adjuvant chemotherapy with cyclophosphamide, methotrexate, and 5-fluorouracil based on clinical and pathologic response in patients with stage
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Docetaxel; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Taxoids | 2010 |
Neoadjuvant chemotherapy with trastuzumab followed by adjuvant trastuzumab versus neoadjuvant chemotherapy alone, in patients with HER2-positive locally advanced breast cancer (the NOAH trial): a randomised controlled superiority trial with a parallel HER
Topics: Adenocarcinoma; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Genes, erbB-2; Humans; Infusions, Intravenous; Methotrexate; Middle Aged; Neoadjuvant Therapy; Paclitaxel; Proportional Hazards Models; Prospective Studies; Receptor, ErbB-2; Time Factors; Trastuzumab | 2010 |
Prolonged disease control after myeloablative chemotherapy, autologous transplantation and immunotherapy in high-risk early breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; CD4-CD8 Ratio; Combined Modality Therapy; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Hematopoietic Stem Cell Transplantation; Humans; Interleukin-2; Killer Cells, Natural; Methotrexate; Middle Aged; Neoplasm Staging; Prospective Studies; Treatment Outcome; Tretinoin | 2010 |
Cyclophosphamide, methotrexate, and fluorouracil; oral cyclophosphamide; levamisole; or no adjuvant therapy for patients with high-risk, premenopausal breast cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Humans; Levamisole; Methotrexate; Middle Aged; Premenopause | 2010 |
Manganese superoxide dismutase polymorphism, treatment-related toxicity and disease-free survival in SWOG 8897 clinical trial for breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Gene Frequency; Genetic Predisposition to Disease; Humans; Logistic Models; Methotrexate; Middle Aged; Neutropenia; Odds Ratio; Phenotype; Polymorphism, Genetic; Prospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Southwestern United States; Superoxide Dismutase; Tamoxifen; Time Factors; Treatment Outcome | 2010 |
Classical cyclophosphamide, methotrexate, and fluorouracil chemotherapy is more effective in triple-negative, node-negative breast cancer: results from two randomized trials of adjuvant chemoendocrine therapy for node-negative breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Immunoenzyme Techniques; Lymph Nodes; Methotrexate; Middle Aged; Neoplasm Staging; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Survival Rate; Treatment Outcome | 2010 |
Epirubicin followed by cyclophosphamide, methotrexate and 5-fluorouracil versus paclitaxel followed by epirubicin and vinorelbine in patients with high-risk operable breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Multivariate Analysis; Paclitaxel; Treatment Outcome; Vinblastine; Vinorelbine | 2010 |
Timing of radiotherapy and outcome in patients receiving adjuvant endocrine therapy.
Topics: Age Factors; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Mastectomy, Segmental; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Proportional Hazards Models; Receptors, Estrogen; Regression Analysis; Tamoxifen; Time Factors | 2011 |
Long-term results of a randomized trial on the sequencing of radiotherapy and chemotherapy in breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Predictive Value of Tests; Prognosis; Prospective Studies; Radiotherapy, Adjuvant; Recurrence; Risk Assessment; Risk Factors; Survival Analysis; Time Factors; Treatment Outcome | 2011 |
Randomized phase III trial of adjuvant epirubicin followed by cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) versus CMF followed by epirubicin in patients with node-negative or 1-3 node-positive rapidly proliferating breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Models, Biological; Proportional Hazards Models; Prospective Studies; Receptors, Estrogen; Treatment Outcome | 2011 |
Dose dense cyclophosphamide, methotrexate, fluorouracil is feasible at 14-day intervals: a pilot study of every-14-day dosing as adjuvant therapy for breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Feasibility Studies; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Pilot Projects; Treatment Outcome | 2010 |
Differential efficacy of three cycles of CMF followed by tamoxifen in patients with ER-positive and ER-negative tumors: long-term follow up on IBCSG Trial IX.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Staging; Prospective Studies; Receptors, Estrogen; Tamoxifen | 2011 |
Quality of life of older patients with early-stage breast cancer receiving adjuvant chemotherapy: a companion study to cancer and leukemia group B 49907.
Topics: Age Factors; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Chemotherapy, Adjuvant; Cyclophosphamide; Deoxycytidine; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Quality of Life; Risk Assessment; Risk Factors; Surveys and Questionnaires; Survival Analysis; Time Factors; Treatment Outcome; United States | 2011 |
Long-term results of International Breast Cancer Study Group Trial VIII: adjuvant chemotherapy plus goserelin compared with either therapy alone for premenopausal patients with node-negative breast cancer.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Goserelin; Humans; Lymph Nodes; Methotrexate; Middle Aged; Neoplasm Staging; Premenopause; Receptors, Estrogen | 2011 |
Evaluation of trastuzumab without chemotherapy as a post-operative adjuvant therapy in HER2-positive elderly breast cancer patients: randomized controlled trial [RESPECT (N-SAS BC07)].
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Cyclophosphamide; Disease-Free Survival; Docetaxel; Doxorubicin; Epirubicin; Female; Fluorouracil; Health Status; Humans; Kaplan-Meier Estimate; Methotrexate; Paclitaxel; Prospective Studies; Quality of Life; Receptor, ErbB-2; Taxoids; Trastuzumab; Treatment Outcome | 2011 |
PREPARE trial: a randomized phase III trial comparing preoperative, dose-dense, dose-intensified chemotherapy with epirubicin, paclitaxel, and CMF versus a standard-dosed epirubicin-cyclophosphamide followed by paclitaxel with or without darbepoetin alfa
Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Darbepoetin alfa; Disease-Free Survival; Dose-Response Relationship, Drug; Epirubicin; Erythropoietin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Paclitaxel; Patient Compliance; Preoperative Care; Treatment Outcome; Young Adult | 2011 |
PREPARE trial: a randomized phase III trial comparing preoperative, dose-dense, dose-intensified chemotherapy with epirubicin, paclitaxel and CMF versus a standard-dosed epirubicin/cyclophosphamide followed by paclitaxel ± darbepoetin alfa in primary brea
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Darbepoetin alfa; Dose-Response Relationship, Drug; Epirubicin; Erythropoietin; Female; Filgrastim; Fluorouracil; Granulocyte Colony-Stimulating Factor; Hemoglobins; Humans; Methotrexate; Middle Aged; Neoadjuvant Therapy; Paclitaxel; Patient Compliance; Polyethylene Glycols; Preoperative Care; Recombinant Proteins; Young Adult | 2011 |
Neoadjuvant and adjuvant chemotherapy of cervical cancer: mature results of the phase 2 PBM-PFU protocol.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Adenosquamous; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Humans; Leucovorin; Maximum Tolerated Dose; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Prospective Studies; Survival Rate; Treatment Outcome; Uterine Cervical Neoplasms; Young Adult | 2011 |
Mitotic activity and bone marrow micrometastases have independent prognostic value in node positive breast cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Cisplatin; Cyclophosphamide; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Lymphatic Metastasis; Methotrexate; Middle Aged; Mitotic Index; Neoplasm Micrometastasis; Prognosis; Tamoxifen; Treatment Outcome | 2011 |
A phase II study of biweekly mitomycin C and irinotecan combination therapy in patients with fluoropyrimidine-resistant advanced gastric cancer: a report from the Gastrointestinal Oncology Group of the Japan Clinical Oncology Group (JCOG0109-DI Trial).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Resistance, Neoplasm; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Japan; Male; Methotrexate; Middle Aged; Mitomycin; Neoplasm Recurrence, Local; Salvage Therapy; Stomach Neoplasms; Survival Rate; Treatment Outcome | 2011 |
Topoisomerase II alpha protein and responsiveness of breast cancer to adjuvant chemotherapy with CEF compared to CMF in the NCIC CTG randomized MA.5 adjuvant trial.
Topics: Adult; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; DNA Topoisomerases, Type II; DNA-Binding Proteins; Epirubicin; Female; Fluorouracil; Gene Amplification; Humans; Immunoenzyme Techniques; In Situ Hybridization, Fluorescence; Methotrexate; Middle Aged; Poly-ADP-Ribose Binding Proteins; Receptor, ErbB-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Treatment Outcome | 2011 |
Pathological complete response rates following different neoadjuvant chemotherapy regimens for operable breast cancer according to ER status, in two parallel, randomized phase II trials with an adaptive study design (ECTO II).
Topics: Adult; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Cyclophosphamide; Deoxycytidine; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm, Residual; Neutropenia; Paclitaxel; Receptors, Estrogen; Treatment Outcome | 2012 |
Effect of the gonadotropin-releasing hormone analogue triptorelin on the occurrence of chemotherapy-induced early menopause in premenopausal women with breast cancer: a randomized trial.
Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Goserelin; Humans; Infertility, Female; Injections, Intramuscular; Luteolytic Agents; Menopause; Methotrexate; Middle Aged; Neoadjuvant Therapy; Premenopause; Primary Ovarian Insufficiency; Tamoxifen; Triptorelin Pamoate | 2011 |
Concurrent vs sequential adjuvant chemotherapy and hormone therapy in breast cancer: a multicenter randomized phase III trial.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Chemotherapy, Adjuvant; Confounding Factors, Epidemiologic; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Glucuronates; Humans; Italy; Kaplan-Meier Estimate; Lymph Node Excision; Mastectomy, Segmental; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Staging; Neoplasms, Hormone-Dependent; Prognosis; Proportional Hazards Models; Receptors, Estrogen; Receptors, Progesterone; Risk Factors; Tamoxifen; Treatment Outcome | 2011 |
Capecitabine versus classical cyclophosphamide, methotrexate, and fluorouracil as first-line chemotherapy for advanced breast cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Cisplatin; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Middle Aged | 2011 |
TIMP-1 in combination with HER2 and TOP2A for prediction of benefit from adjuvant anthracyclines in high-risk breast cancer patients.
Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; DNA Topoisomerases, Type II; DNA-Binding Proteins; Epirubicin; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Methotrexate; Middle Aged; Multivariate Analysis; Mutation; Poly-ADP-Ribose Binding Proteins; Proportional Hazards Models; Receptor, ErbB-2; Tissue Inhibitor of Metalloproteinase-1; Treatment Outcome | 2012 |
Postoperative dose-dense sequential versus concomitant administration of epirubicin and paclitaxel in patients with node-positive breast cancer: 5-year results of the Hellenic Cooperative Oncology Group HE 10/00 phase III Trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Greece; Humans; Kaplan-Meier Estimate; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Proportional Hazards Models; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Young Adult | 2012 |
Responsiveness of intrinsic subtypes to adjuvant anthracycline substitution in the NCIC.CTG MA.5 randomized trial.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Cytarabine; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Receptor, ErbB-2 | 2012 |
Persistence, adherence, and toxicity with oral CMF in older women with early-stage breast cancer (Adherence Companion Study 60104 for CALGB 49907).
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Chemotherapy, Adjuvant; Cyclophosphamide; Deoxycytidine; Female; Fluorouracil; Humans; Medication Adherence; Methotrexate; Patient Compliance | 2012 |
Preventing weight gain during adjuvant chemotherapy for breast cancer: a dietary intervention study.
Topics: Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Cyclophosphamide; Diet, Macrobiotic; Diet, Mediterranean; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Overweight; Taxoids; Treatment Outcome; Weight Gain | 2012 |
Adjuvant epirubicin followed by cyclophosphamide, methotrexate and fluorouracil (CMF) vs CMF in early breast cancer: results with over 7 years median follow-up from the randomised phase III NEAT/BR9601 trials.
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Medication Adherence; Methotrexate; Middle Aged | 2012 |
Prognostic interaction between expression of p53 and estrogen receptor in patients with node-negative breast cancer: results from IBCSG Trials VIII and IX.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Goserelin; Humans; Lymph Nodes; Methotrexate; Middle Aged; Receptors, Estrogen; Tamoxifen; Tissue Array Analysis; Treatment Outcome; Tumor Suppressor Protein p53 | 2012 |
The prognostic and predictive value of mRNA expression of vascular endothelial growth factor family members in breast cancer: a study in primary tumors of high-risk early breast cancer patients participating in a randomized Hellenic Cooperative Oncology G
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemoradiotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization, Fluorescence; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor B; Vascular Endothelial Growth Factor C; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factor Receptor-3; Vascular Endothelial Growth Factors; Young Adult | 2012 |
Overall survival benefit for sequential doxorubicin-docetaxel compared with concurrent doxorubicin and docetaxel in node-positive breast cancer--8-year results of the Breast International Group 02-98 phase III trial.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Docetaxel; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Taxoids; Young Adult | 2013 |
Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Docetaxel; Doxorubicin; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Lymph Nodes; Lymphatic Metastasis; Lymphocytes, Tumor-Infiltrating; Methotrexate; Middle Aged; Predictive Value of Tests; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Taxoids; Treatment Outcome | 2013 |
Ten-year analysis of the prospective multicentre Chemo-N0 trial validates American Society of Clinical Oncology (ASCO)-recommended biomarkers uPA and PAI-1 for therapy decision making in node-negative breast cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Decision Making; Disease-Free Survival; Drug Therapy; Enzyme-Linked Immunosorbent Assay; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Plasminogen Activator Inhibitor 1; Prognosis; Prospective Studies; Risk Factors; Time Factors; Treatment Outcome; Urokinase-Type Plasminogen Activator | 2013 |
Is TIMP-1 immunoreactivity alone or in combination with other markers a predictor of benefit from anthracyclines in the BR9601 adjuvant breast cancer chemotherapy trial?
Topics: Adult; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cohort Studies; Cyclophosphamide; DNA Topoisomerases, Type II; DNA-Binding Proteins; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Gene Dosage; Humans; Immunoenzyme Techniques; In Situ Hybridization, Fluorescence; Methotrexate; Middle Aged; Neoplasm Grading; Poly-ADP-Ribose Binding Proteins; Prognosis; Receptor, ErbB-2; Survival Rate; Tissue Inhibitor of Metalloproteinase-1 | 2013 |
One year of adjuvant tamoxifen compared with chemotherapy and tamoxifen in postmenopausal patients with stage II breast cancer.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Methotrexate; Middle Aged; Nausea; Neoplasm Staging; Postmenopause; Registries; Tamoxifen; Treatment Outcome; Vomiting | 2013 |
High Ki67 predicts unfavourable outcomes in early breast cancer patients with a clinically clear axilla who do not receive axillary dissection or axillary radiotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Ki-67 Antigen; Lymph Nodes; Methotrexate; Middle Aged; Prognosis; Proportional Hazards Models; Radiotherapy, Adjuvant; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Tamoxifen; Treatment Outcome; Triple Negative Breast Neoplasms | 2013 |
Randomized Phase III study of 5-fluorouracil continuous infusion vs. sequential methotrexate and 5-fluorouracil therapy in far advanced gastric cancer with peritoneal metastasis (JCOG0106).
Topics: Adult; Aged; Anorexia; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Staging; Neutropenia; Odds Ratio; Peritoneal Neoplasms; Stomach Neoplasms; Treatment Outcome | 2013 |
Effectiveness and safety of intensive triplet chemotherapy plus bevacizumab, FIr-B/FOx, in young-elderly metastatic colorectal cancer patients.
Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Carboplatin; Clinical Trials, Phase II as Topic; Colorectal Neoplasms; Demography; DNA Mutational Analysis; Dose-Response Relationship, Drug; Female; Fluorouracil; Genotype; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Methotrexate; Neoplasm Metastasis; Organoplatinum Compounds; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Treatment Outcome | 2013 |
Sixteen years follow-up results of a randomized phase II trial of neoadjuvant fluorouracil, doxorubicin, and cyclophosphamide (FAC) compared with cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) in stage III breast cancer: GOCS experience.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Prospective Studies; Survival; Young Adult | 2014 |
Benefit from anthracyclines in relation to biological profiles in early breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cyclophosphamide; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Humans; Immunohistochemistry; Ki-67 Antigen; Methotrexate; Middle Aged; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Triple Negative Breast Neoplasms | 2014 |
Assessment of microtubule-associated protein (MAP)-Tau expression as a predictive and prognostic marker in TACT; a trial assessing substitution of sequential docetaxel for FEC as adjuvant chemotherapy for early breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Docetaxel; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; tau Proteins; Taxoids | 2014 |
BRCA-1 methylation and TP53 mutation in triple-negative breast cancer patients without pathological complete response to taxane-based neoadjuvant chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BRCA1 Protein; Capecitabine; Cyclophosphamide; Deoxycytidine; Disease-Free Survival; DNA Methylation; Female; Fluorouracil; Genes, BRCA1; Genes, p53; Germ-Line Mutation; Humans; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Paraffin Embedding; Prospective Studies; Taxoids; Triple Negative Breast Neoplasms | 2014 |
Relationship between the prognostic and predictive value of the intrinsic subtypes and a validated gene profile predictive of loco-regional control and benefit from post-mastectomy radiotherapy in patients with high-risk breast cancer.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemoradiotherapy; Cyclophosphamide; ErbB Receptors; Female; Fluorouracil; Gene Expression Profiling; Humans; Immunohistochemistry; Ki-67 Antigen; Lymph Node Excision; Mastectomy; Methotrexate; Neoplasm Recurrence, Local; Predictive Value of Tests; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 2014 |
Comparison of patient reported quality of life and impact of treatment side effects experienced with a taxane-containing regimen and standard anthracycline based chemotherapy for early breast cancer: 6 year results from the UK TACT trial (CRUK/01/001).
Topics: Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Quality of Life; Surveys and Questionnaires; Tamoxifen; Taxoids; Therapeutics; United Kingdom | 2014 |
The RAD51 135G>C polymorphism is related to the effect of adjuvant therapy in early breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Cytosine; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prognosis; Rad51 Recombinase; Radiotherapy, Adjuvant; Sequence Analysis, DNA; Treatment Outcome | 2015 |
Weekly docetaxel versus CMF as adjuvant chemotherapy for older women with early breast cancer: final results of the randomized phase III ELDA trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Cyclophosphamide; Docetaxel; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Survival Rate; Taxoids | 2015 |
p53 status identifies triple-negative breast cancer patients who do not respond to adjuvant chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Female; Fluorouracil; Genes, p53; Humans; Mastectomy; Methotrexate; Neoplasm Recurrence, Local; Phenotype; Prognosis; Prospective Studies; Survival Analysis; Topoisomerase II Inhibitors; Treatment Outcome; Triple Negative Breast Neoplasms; Tumor Suppressor Protein p53 | 2015 |
Gefitinib, Methotrexate and Methotrexate plus 5-Fluorouracil as palliative treatment in recurrent head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluorouracil; Gefitinib; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Quality of Life; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2015 |
A randomized phase 2 study comparing EC or CMF versus nab-paclitaxel plus capecitabine as adjuvant chemotherapy for nonfrail elderly patients with moderate to high-risk early breast cancer (ICE II-GBG 52).
Topics: Aged; Aged, 80 and over; Albumins; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Administration Routes; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Paclitaxel; Treatment Outcome | 2015 |
Prognostic Significance of VEGFC and VEGFR1 mRNA Expression According to HER2 Status in Breast Cancer: A Study of Primary Tumors from Patients with High-risk Early Breast Cancer Participating in a Randomized Hellenic Cooperative Oncology Group Trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Middle Aged; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Vascular Endothelial Growth Factor C; Vascular Endothelial Growth Factor Receptor-1; Young Adult | 2015 |
Cardiac assessment of early breast cancer patients 18 years after treatment with cyclophosphamide-, methotrexate-, fluorouracil- or epirubicin-based chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Echocardiography; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Heart Failure; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Outcome Assessment, Health Care; Prognosis; Proportional Hazards Models; Survival Rate; Ventricular Dysfunction, Left | 2015 |
Effects of Fresh Yellow Onion Consumption on CEA, CA125 and Hepatic Enzymes in Breast Cancer Patients: A Double- Blind Randomized Controlled Clinical Trial.
Topics: Adult; Aged; Alkaline Phosphatase; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Breast Neoplasms; CA-125 Antigen; Carcinoembryonic Antigen; Cyclophosphamide; Diet; Docetaxel; Double-Blind Method; Doxorubicin; Feeding Behavior; Female; Fluorouracil; Humans; Liver; Membrane Proteins; Methotrexate; Middle Aged; Onions; Placebos; Plant Preparations; Taxoids | 2015 |
Impact of body mass index (BMI) on the prognosis of high-risk early breast cancer (EBC) patients treated with adjuvant chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Obesity; Prognosis; Survival Analysis; Treatment Outcome; Young Adult | 2016 |
No breast cancer subgroup can be spared postoperative radiotherapy after breast-conserving surgery. Fifteen-year results from the Swedish Breast Cancer Group randomised trial, SweBCG 91 RT.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Estrogen Antagonists; Female; Fluorouracil; Follow-Up Studies; Humans; Longitudinal Studies; Lymph Node Excision; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Radiotherapy, Adjuvant; Sweden; Tamoxifen; Tumor Burden | 2016 |
Cardiac safety, efficacy, and correlation of serial serum HER2-extracellular domain shed antigen measurement with the outcome of the combined trastuzumab plus CMF in women with HER2-positive metastatic breast cancer: results from the EORTC 10995 phase II
Topics: Anthracyclines; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiotoxicity; Cyclophosphamide; Disease-Free Survival; Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Heart; Humans; Methotrexate; Neoplasm Metastasis; Receptor, ErbB-2; Trastuzumab | 2017 |
Lymphedema, musculoskeletal events and arm function in older patients receiving adjuvant chemotherapy for breast cancer (Alliance A171302).
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arm; Breast Neoplasms; Capecitabine; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphedema; Methotrexate; Muscle, Skeletal | 2017 |
Uterine artery embolization combined with local infusion of methotrexate and 5- fluorouracil in treating ectopic pregnancy: A CONSORT-compliant article.
Topics: Abortifacient Agents; Adult; Antimetabolites; Chorionic Gonadotropin; Combined Modality Therapy; Female; Fluorouracil; Folic Acid Antagonists; Humans; Injections, Intra-Arterial; Methotrexate; Pregnancy; Pregnancy, Ectopic; Treatment Outcome; Uterine Artery Embolization; Young Adult | 2018 |
Randomized Trial of Standard Adjuvant Chemotherapy Regimens Versus Capecitabine in Older Women With Early Breast Cancer: 10-Year Update of the CALGB 49907 Trial.
Topics: Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Survival Rate; Treatment Outcome | 2019 |
Clinical Outcomes in Early Breast Cancer With a High 21-Gene Recurrence Score of 26 to 100 Assigned to Adjuvant Chemotherapy Plus Endocrine Therapy: A Secondary Analysis of the TAILORx Randomized Clinical Trial.
Topics: Adult; Aged; Anthracyclines; Antineoplastic Agents; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Cyclophosphamide; Docetaxel; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Taxoids; Treatment Outcome; Young Adult | 2020 |
Synchronous versus sequential chemo-radiotherapy in patients with early stage breast cancer (SECRAB): A randomised, phase III, trial.
Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemoradiotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prospective Studies; Treatment Outcome; Young Adult | 2020 |
Topical calcipotriol combined with urea 20% versus intralesional injection of triamcinolone acetonide, 5-fluorouracil, and methotrexate in the treatment of nail psoriasis: A comparative study.
Topics: Calcitriol; Dermatologic Agents; Fluorouracil; Humans; Injections, Intralesional; Methotrexate; Nail Diseases; Psoriasis; Treatment Outcome; Triamcinolone Acetonide; Urea | 2022 |
Randomised comparison of fluorouracil, epidoxorubicin and methotrexate (FEMTX) plus supportive care with supportive care alone in patients with non-resectable gastric cancer: S Pyrhönen, T Kuitunen, P Nyandoto & M Kouri.
Topics: Antineoplastic Combined Chemotherapy Protocols; Epirubicin; Fluorouracil; Humans; Methotrexate; Stomach Neoplasms | 2023 |
Detailed Sub-study Analysis of the SECRAB Trial: Quality of Life, Cosmesis and Chemotherapy Dose Intensity.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Prospective Studies; Quality of Life | 2023 |
2340 other study(ies) available for fluorouracil and methotrexate
| Article | Year |
|---|---|
Antitumor agents. 1. 1,4-Bis[(aminoalkyl)amino]-9,10-anthracenediones.
Topics: Animals; Anthracenes; Antineoplastic Agents; Leukemia, Experimental; Mice; Neoplasms, Experimental; Structure-Activity Relationship | 1979 |
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Synthesis and biological evaluation of N4-substituted imidazo- and v-triazolo[4,5-d]pyridazine nucleosides.
Topics: Adenosine Deaminase Inhibitors; Animals; Antineoplastic Agents; Cattle; Humans; Leukemia L1210; Melanoma, Experimental; Mice; Nucleosides; Pyridazines; Structure-Activity Relationship; Tumor Cells, Cultured | 1993 |
Synthesis of 11,12-epoxydrim-8,12-en-11-ol, 11,12-diacetoxydrimane, and warburganal from (-)-sclareol.
Topics: Animals; Antineoplastic Agents; Benzofurans; Diterpenes; Drug Screening Assays, Antitumor; Humans; Leukemia P388; Naphthalenes; Porifera; Sesquiterpenes; Structure-Activity Relationship; Tumor Cells, Cultured | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water | 2010 |
Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2,6-substituted-quinazolin-4-ones.
Topics: Anti-Infective Agents; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Quinazolinones; Static Electricity; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Synthesis and antiproliferative activity of 4-substituted-piperazine-1-carbodithioate derivatives of 2,4-diaminoquinazoline.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; HCT116 Cells; HeLa Cells; HT29 Cells; Humans; MCF-7 Cells; Molecular Structure; Piperazines; Quinazolines; Structure-Activity Relationship; Thiocarbamates | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Nonclassical antifolates, part 5. Benzodiazepine analogs as a new class of DHFR inhibitors: synthesis, antitumor testing and molecular modeling study.
Topics: Benzodiazepines; Enzyme Inhibitors; Folic Acid Antagonists; Models, Molecular; Structure-Activity Relationship | 2014 |
Synthesis, biological evaluation and molecular modeling study of some new methoxylated 2-benzylthio-quinazoline-4(3H)-ones as nonclassical antifolates.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Inhibitory Concentration 50; Microbial Sensitivity Tests; Models, Molecular; Quinazolines | 2016 |
Synthesis and antiproliferative activity of a series of novel 6-substituted pyrido[3,2-d]pyrimidines as potential nonclassical lipophilic antifolates targeting dihydrofolate reductase.
Topics: Antineoplastic Agents; Cell Cycle; Diamines; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Humans; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Neoplasms; Pyrimidines; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Tumor Cells, Cultured | 2017 |
Comprehensive study on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamides.
Topics: Benzenesulfonamides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Line; Dose-Response Relationship, Drug; Humans; Isoenzymes; Models, Molecular; Molecular Structure; Pyrazoles; Structure-Activity Relationship; Sulfonamides | 2021 |
Chemotherapeutic drugs increase killing of tumor cells by antibody and complement.
Topics: Animals; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cell Line; Complement System Proteins; Cyclophosphamide; Cytarabine; Fluorouracil; Guinea Pigs; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Nitrosamines; Vincristine | 1975 |
Kinetically-based multiple drug treatment for advanced head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Ear Neoplasms; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Laryngeal Neoplasms; Maxillary Neoplasms; Mercaptopurine; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasms; Tongue Neoplasms; Tonsillar Neoplasms; Vincristine | 1975 |
Letter: Treatment of small-cell carcinoma of bronchus.
Topics: Adult; Aged; Bronchial Neoplasms; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Radiotherapy Dosage; Vincristine | 1975 |
Esophageal carcinoma. The value of staging in long-term survival.
Topics: Administration, Oral; Cyclophosphamide; Esophageal Neoplasms; Esophagus; Female; Fluorouracil; Follow-Up Studies; Humans; Injections, Intravenous; Lymphatic Metastasis; Male; Methotrexate; Neoplasm Metastasis; Palliative Care; Prednisone; Vincristine | 1975 |
Effects of antineoplastic agents on wound healing in mice.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cyclophosphamide; Dactinomycin; Doxorubicin; Fluorouracil; Injections, Intraperitoneal; Male; Melanoma; Methotrexate; Mice; Neoplasms, Experimental; Vincristine; Wound Healing | 1975 |
Bleomycin combination chemotherapy in the management of testicular neoplasia.
Topics: Abdominal Neoplasms; Adult; Bleomycin; Cyclophosphamide; Drug Therapy, Combination; Dysgerminoma; Fluorouracil; Humans; Leukopenia; Lung Neoplasms; Male; Mediastinal Neoplasms; Methotrexate; Neoplasm Metastasis; Pneumonia; Retroperitoneal Neoplasms; Teratoma; Testicular Neoplasms; Vinblastine; Vincristine | 1975 |
The role of chemotherapy in the management of cancer of the head and neck: a review.
Topics: Bleomycin; Dinitrochlorobenzene; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Immunotherapy; Infusions, Parenteral; Injections, Intra-Arterial; Leucovorin; Methotrexate; Mouth Neoplasms; Recurrence | 1975 |
[Sensitivity tests of malignant tumours against cytostatic agents in vitro and in vivo/studies on the mouse sarcoma 180 (author's transl)].
Topics: Animals; Antineoplastic Agents; Biological Transport; Bleomycin; Cell Membrane Permeability; Cells, Cultured; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Fluorouracil; Methotrexate; Mice; Mice, Inbred Strains; Podophyllin; Sarcoma 180; Uridine | 1975 |
Enhancing effect by metabolic inhibitors on the killing of tumor cells by antibody and complement.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cells, Cultured; Complement System Proteins; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Fluorouracil; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms, Experimental; Puromycin; Vincristine | 1975 |
Hepatic artery ligation and prolonged cytotoxic therapy in advanced primary and secondary liver tumours.
Topics: Adult; Aged; Antineoplastic Agents; Bilirubin; Biopsy; Catheterization; Female; Fluorouracil; Hepatic Artery; Humans; Leucovorin; Ligation; Liver Function Tests; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Palliative Care; Pulmonary Embolism | 1975 |
Seven-drug polychemotherapy in the treatment of advanced and recurrent squamous carcinoma of the female genital tract.
Topics: Adult; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Cytarabine; Dactinomycin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Uterine Cervical Neoplasms; Vincristine | 1975 |
Chemotherapy and palliative therapy in malignant disease of the maxillary sinus.
Topics: Bleomycin; Fluorouracil; Humans; Maxillary Sinus; Methotrexate; Paranasal Sinus Neoplasms | 1976 |
[Chemoradiation therapy of inoperable lung cancer].
Topics: Adenocarcinoma; Adult; Aged; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Dactinomycin; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Radioisotope Teletherapy; Time Factors | 1975 |
Letter: Chemotherapy after mastectomy.
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Postoperative Care | 1976 |
Retroperitoneal lymphadenectomy as adjunctive therapy in selected cases of advanced testicular carcinoma.
Topics: Adolescent; Adult; Bleomycin; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Lymph Node Excision; Male; Methotrexate; Retroperitoneal Neoplasms; Teratoma; Testicular Neoplasms; Vinblastine; Vincristine | 1976 |
Regional chemotherapy with combined drugs in cancer of the head and neck.
Topics: Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Palliative Care; Remission, Spontaneous; Time Factors | 1976 |
Quadruple chemotherapy in advanced squamous cell carcinoma of the head and neck.
Topics: Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Combinations; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate | 1976 |
Bleomycin (NSC-125066) followed by cyclophosphamide (NSC-26271), vincristine (NSC-67574), methotrexate (NSC-740), and 5-fllorouracil (NSC-19893) for non-oat cell bronchogenic carcinoma.
Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Prognosis; Vincristine | 1976 |
[Recent personal results in advanced bronchial cancer. Palliative immuno-chemotherapy. 63 cases].
Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Emetine; Female; Fluorouracil; Humans; Immunotherapy; Lomustine; Male; Methotrexate; Middle Aged; Mitomycins; Palliative Care; Propionibacterium acnes; Vincristine | 1976 |
Hair growth inhibition as a method of screening drugs for local antimitotic activity.
Topics: Animals; Antineoplastic Agents; Bleomycin; Colchicine; Cyclophosphamide; Cytarabine; Drug Evaluation, Preclinical; Fluorouracil; Guinea Pigs; Hair; Hydroxyurea; Injections, Intradermal; Mechlorethamine; Methotrexate; Mitosis; Thiotepa; Vincristine | 1977 |
Ten model mutagens evaluated by the micronucleus test.
Topics: Animals; Bleomycin; Bone Marrow; Bone Marrow Cells; Cell Line; Cell Nucleus; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Demecolcine; Dose-Response Relationship, Drug; Doxorubicin; Erythroblasts; Fluorouracil; Genetic Techniques; Mercaptopurine; Methotrexate; Mice; Mutagens; Thiotepa; Vincristine | 1976 |
Combination chemotherapy in germinal cell tumors.
Topics: Adolescent; Adult; Antineoplastic Agents; Bleomycin; Choriocarcinoma; Cyclophosphamide; Drug Therapy, Combination; Dysgerminoma; Fluorouracil; Humans; Male; Methotrexate; Neoplasm Metastasis; Teratoma; Testicular Neoplasms; Vinblastine; Vincristine | 1976 |
On the combined action of drugs on the lambda prophage induction in Escherichia coli K12 cells.
Topics: Coliphages; Drug Synergism; Escherichia coli; Fluorouracil; Idoxuridine; Methotrexate; Virus Replication | 1977 |
Ovarian function in patients receiving adjuvant chemotherapy for breast cancer.
Topics: Adult; Aged; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Dehydroepiandrosterone; Drug Therapy, Combination; Estradiol; Estrone; Female; Fluorouracil; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Lymphatic Metastasis; Melphalan; Menopause; Methotrexate; Middle Aged; Ovary; Vincristine | 1977 |
Clinical pharmacology of anticancer drugs.
Topics: Animals; Antineoplastic Agents; Azacitidine; Bleomycin; Cyclophosphamide; Cytarabine; Dacarbazine; Daunorubicin; Doxorubicin; Female; Fluorouracil; Heart; Humans; Leucovorin; Lung; Male; Methotrexate; Neoplasms; Nitrosourea Compounds; Procarbazine; Triazenes; Vinblastine; Vincristine | 1977 |
Antibody-drug synergism: An assessment of specific passive immunotherapy in bronchial carcinoma.
Topics: Animals; Antibodies, Neoplasm; Antineoplastic Agents; Bleomycin; Bronchial Neoplasms; Carcinoma; Cyclophosphamide; Doxorubicin; Drug Synergism; Evaluation Studies as Topic; Female; Fluorouracil; Follow-Up Studies; Goats; Humans; Immunoglobulins; Injections, Intramuscular; Injections, Intravenous; Male; Methotrexate; Middle Aged; Postoperative Care | 1977 |
Chemotherapy studies in autochthonous rat tumors. Forestomach and bladder cancer.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carcinoma in Situ; Doxorubicin; Drug Combinations; Female; Fluorouracil; Methotrexate; Neoplasms, Experimental; Papilloma; Rats; Stomach Neoplasms; Urinary Bladder Neoplasms | 1977 |
Synergistic effects of the combination of cis-platinum diamminodichloride and 2,2'-anhydro-1-beta-D-arabinofuranosyl-5-fluorocytosine in transplanted mouse leukemias.
Topics: Ancitabine; Animals; Cells, Cultured; Cisplatin; Cytarabine; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Leukemia L1210; Leukemia, Experimental; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA | 1977 |
Chemotherapy for lung cancer.
Topics: Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Fluorouracil; Humans; Lomustine; Lung Neoplasms; Methotrexate; Procarbazine; Vinblastine; Vincristine | 1978 |
Osteonecrosis after chemotherapy.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Humerus; Methotrexate; Middle Aged; Osteonecrosis | 1978 |
Adriamycin alone or in combination in 100 patients with carcinoma of the cervix or vagina.
Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Uterine Cervical Neoplasms; Vaginal Neoplasms; Vincristine | 1978 |
Palliation of inoperable head and heck cancer: combined intra-arterial infusion chemotherapy and irradiation.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Carotid Artery, External; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Palliative Care; Vincristine | 1978 |
Combination chemotherapy of head and neck cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bleomycin; Bone Marrow; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Fistula; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mucous Membrane; Nasopharyngeal Neoplasms; Prognosis; Remission, Spontaneous; Salivary Gland Neoplasms; Vincristine | 1978 |
[Parenteral feeding during aggressive chemotherapy of various neoplasms].
Topics: Adult; Bleomycin; Body Weight; Cachexia; Cyclophosphamide; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasms; Parenteral Nutrition; Vincristine | 1978 |
[Current status of chemotherapy in malignant head and neck neoplasms (proceedings)].
Topics: Animals; Bleomycin; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Rats | 1979 |
Chemotherapy for oral malignant disease.
Topics: Antineoplastic Agents; Bleomycin; Drug Therapy, Combination; Fluorouracil; Humans; Hydroxyurea; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms; Prognosis; Vinblastine | 1979 |
Cyclophosphamide, methotrexate, 5-fluorouracil (CMF) in advanced gastrointestinal cancer.
Topics: Aged; Bone Marrow; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Methotrexate; Middle Aged; Palliative Care; Remission, Spontaneous; Vomiting | 1979 |
Hepatic function assessed (in rats) during chemotherapy with some anti-cancer drugs.
Topics: Alkaline Phosphatase; alpha-Fetoproteins; Animals; Antipyrine; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Cyclophosphamide; Dactinomycin; Fluorouracil; gamma-Glutamyltransferase; Glutamate Dehydrogenase; Liver; Male; Methotrexate; Ornithine Carbamoyltransferase; Rats; Vincristine | 1979 |
New developments on the mechanisms of action of antineoplastic drugs.
Topics: Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Interactions; Drug Synergism; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Methotrexate | 1979 |
Chemotherapy studies in autochthonous rat tumors: carcinomas of the forestomach.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Dimethylnitrosamine; Drug Evaluation, Preclinical; Fluorouracil; Male; Methotrexate; Neoplasms, Experimental; Rats; Stomach Neoplasms | 1979 |
[Chemotherapy as an adjuvant treatment in breast cancer (author's transl)].
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Fluorouracil; Humans; Melphalan; Methotrexate; Thiotepa | 1978 |
Intraperitoneal contrast infusion for assessment of intraperitoneal fluid dynamics.
Topics: Adult; Antineoplastic Agents; Ascitic Fluid; Contrast Media; Female; Fluorouracil; Humans; Injections, Intraperitoneal; Melanoma; Methotrexate; Middle Aged; Neoplasm Metastasis; Ovarian Neoplasms; Peritoneal Neoplasms; Peritoneum; Tomography, X-Ray Computed | 1979 |
Retroperitoneal germ cell tumors with no apparent testicular involvement.
Topics: Adult; Biopsy; Cyclophosphamide; Dysgerminoma; Fluorouracil; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Plicamycin; Retroperitoneal Neoplasms; Teratoma; Testicular Neoplasms; Vincristine | 1975 |
[Treatment of primary and secondary liver tumors using a combination of chemotherapy and surgery].
Topics: Antineoplastic Agents; Carmustine; Drug Therapy, Combination; Floxuridine; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Methods; Methotrexate; Remission, Spontaneous; Vincristine | 1975 |
Effects of cancer chemotherapeutic agents on endocrine organs and serum levels of estrogens, progesterone, prolactin, and luteinizing hormone.
Topics: Animals; Antineoplastic Agents; Dehydroepiandrosterone; Endocrine Glands; Estradiol; Estrogens; Estrus; Female; Fluorouracil; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Luteinizing Hormone; Methotrexate; Nitrogen Mustard Compounds; Nitrosourea Compounds; Organ Size; Pregnancy; Progesterone; Prolactin; Radioimmunoassay; Rats; Vinblastine; Vincristine | 1975 |
The chemotherapy of urologic cancer.
Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Doxorubicin; Drug Therapy, Combination; Estradiol; Female; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Kidney Neoplasms; Male; Methotrexate; Middle Aged; Mitomycins; Plicamycin; Prostatic Neoplasms; Testicular Neoplasms; Thiotepa; Urinary Bladder Neoplasms; Urogenital Neoplasms; Vincristine | 1975 |
Schedule-dependent effect of phase-specific cytotoxic agents on production of hemolytic plaque-forming cells.
Topics: Animals; Antineoplastic Agents; Cytarabine; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Male; Methotrexate; Mice; Mice, Inbred AKR; Time Factors | 1976 |
Chemotherapy studies in autochthonous rat tumors intestinal cancer.
Topics: Adenocarcinoma; Animals; Cyclophosphamide; Dimethylhydrazines; Dimethylnitrosamine; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Male; Methotrexate; Methylnitronitrosoguanidine; Rats | 1978 |
Letter: Osteoblastic repair of osteolytic tumor metastases following treatment.
Topics: Adult; Antineoplastic Agents; Bone Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Osteoblasts; Radiography; Remission, Spontaneous | 1975 |
Islet cell carcinoma of the pancreas.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Child; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Humans; Hyperglycemia; Hypoglycemia; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Pancreas; Pancreatic Neoplasms; Streptozocin | 1975 |
Recent trends in chemotherapy of solid tumors.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Cyclophosphamide; Esophageal Neoplasms; Female; Fluorouracil; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Melanoma; Methotrexate; Neoplasms; Pancreatic Neoplasms; Radiotherapy, High-Energy; Sarcoma; Urogenital Neoplasms | 1975 |
Current status of regional arterial infusion chemotherapy.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Hepatocellular; Carotid Arteries; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Hepatic Artery; Humans; Liver Neoplasms; Melanoma; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasms; Temporal Arteries; Time Factors | 1975 |
Regression of established tumors and induction of tumor immunity by intratumor chemotherapy.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Carmustine; Dacarbazine; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Graft Rejection; Guinea Pigs; Injections; Injections, Intraperitoneal; Liver Neoplasms; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Neoplasm Transplantation; Neoplasms, Experimental | 1976 |
[Chemotherapy of breast cancer].
Topics: Adenocarcinoma, Scirrhous; Breast Neoplasms; Calcinosis; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged | 1976 |
[After care in bronchial carcinoma. Results of postoperative polychemotherapy].
Topics: Aftercare; Aged; Antineoplastic Agents; Austria; Carcinoma, Bronchogenic; Cyclophosphamide; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Time Factors; Vinblastine | 1976 |
Combination chemotherapy with 5--fluorouracil, amethopterin (methotrexate) and prednisolone (FAP protocol) in the therapy of cholangiocarcinoma.
Topics: Adenoma, Bile Duct; Drug Therapy, Combination; Fluorouracil; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisolone | 1976 |
[Experiences with drug therapy of advanced metastatic carcinoma of the breast (author's transl)].
Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Thoracic Neoplasms; Vincristine | 1976 |
Combination chemotherapy of L1210 leukemia with platinum compounds and cyclophosphamide plus other selected antineoplastic agents.
Topics: Animals; Cell Survival; Cisplatin; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fluorouracil; Leukemia L1210; Mesylates; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Organometallic Compounds; Platinum; Propylamines; Vincristine | 1976 |
Chemotherapy studies in autochthonous rat tumors: hepatomas.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Nitrosamines; Rats; Time Factors | 1977 |
Mastectomy as an adjunct to combination chemotherapy.
Topics: Adenocarcinoma; Administration, Oral; Adult; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Injections, Intravenous; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Prednisone; Vincristine | 1978 |
Treatment of primary liver cancer: response to regional chemotherapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Chemotherapy, Cancer, Regional Perfusion; Doxorubicin; Female; Floxuridine; Fluorouracil; Hepatectomy; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Prognosis | 1979 |
COMF-radiotherapy treatment of small cell carcinoma of the lung.
Topics: Carcinoma, Small Cell; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Vincristine | 1979 |
Nursing the woman receiving adjuvant chemotherapy for breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Patient Education as Topic | 1978 |
Current trends and prospects in surgical adjuvant trials.
Topics: Antineoplastic Agents; Breast Neoplasms; Cisplatin; Colonic Neoplasms; Cyclophosphamide; Dianhydrogalactitol; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Melphalan; Methotrexate; Neoplasms; Osteosarcoma; Rectal Neoplasms | 1978 |
Heparinized chemotherapy in the treatment of disseminated lung cancer.
Topics: Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Heparin; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Pleural Effusion; Vincristine | 1979 |
Leucovorin in combination chemotherapy of breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone | 1977 |
Treatment of advanced bronchogenic carcinoma with adriamycin, 5-fluorouracil and methotrexate.
Topics: Carcinoma, Bronchogenic; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leucovorin; Lung Neoplasms; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Time Factors | 1977 |
Effect of sequence of administration of methotrexate, leucovorin, and 5-fluorouracil on mammary tumor growth and survival in syngeneic C3H mice.
Topics: Animals; Antibody Formation; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Immunity, Cellular; Leucovorin; Male; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mice, Inbred C3H | 1977 |
Toward improved selectivity in cancer chemotherapy: the Richard and Hinda Rosenthal Foundation Award Lecture.
Topics: Animals; Antineoplastic Agents; Carboxypeptidases; Drug Resistance; Drug Therapy, Combination; Fluorouracil; Folic Acid; Folic Acid Antagonists; Humans; Leucovorin; Methotrexate; Neoplasms; Uracil Nucleotides | 1979 |
[Pharmacokinetics of antineoplastic agents (author's transl)].
Topics: Antineoplastic Agents; Cyclophosphamide; Cytarabine; Doxorubicin; Fluorouracil; Humans; Kinetics; Leucovorin; Methotrexate | 1979 |
Sensitization of resistant myeloid leukemia clone cells by anti-cancer drugs to factor-stimulating differentiation.
Topics: Antineoplastic Agents; Ascitic Fluid; Cell Differentiation; Cell Line; Clone Cells; Colony-Stimulating Factors; Daunorubicin; Doxorubicin; Fluorouracil; In Vitro Techniques; Leukemia, Myeloid; Methotrexate; Mitomycins; Muramidase; Phagocytosis | 1979 |
Effect of Bacillus Calmette-Guérin on immunosuppression from cyclophosphamide, methotrexate, and 5-fluorouracil.
Topics: Animals; BCG Vaccine; Cyclophosphamide; Erythrocytes; Female; Fluorouracil; Graft Survival; Immunity; Immunity, Cellular; Immunosuppression Therapy; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Organ Size; Skin Transplantation; Spleen; Transplantation, Homologous | 1977 |
Chemoimmunotherapy of metastatic large bowel cancer: nonspecific stimulation with BCG and levamisole.
Topics: BCG Vaccine; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Levamisole; Lomustine; Methotrexate; Neoplasm Metastasis; Rectal Neoplasms; Tegafur | 1977 |
Adjuvant chemo-immuno-therapy with LMF+BCG in node-negeative and node-positive breast cancer.
Topics: Antineoplastic Agents; BCG Vaccine; Breast Neoplasms; Chlorambucil; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunotherapy; Mastectomy; Methotrexate; Mycobacterium bovis; Prednisone; Recurrence | 1978 |
[Synergistic therapeutic effect of adriamycin with 5-fluor-uracil, with prednisolon and with cyclophosphamide on chemically induced mammary cancer of the rat (author's transl)].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Mammary Neoplasms, Experimental; Methotrexate; Prednisolone; Rats; Vincristine | 1977 |
[Chemotherapy of the ovarian carcinoma (author's transl)].
Topics: Altretamine; Antineoplastic Agents; Chlorambucil; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hydroxyprogesterones; Mechlorethamine; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Nitrosourea Compounds; Ovarian Neoplasms; Thiotepa; Vinblastine; Vincristine | 1977 |
Microbiologic assays of cancer chemotherapeutic agents.
Topics: Antineoplastic Agents; Biological Assay; Cytarabine; Fluorouracil; Folic Acid; Lacticaseibacillus casei; Leucovorin; Mercaptopurine; Methotrexate; Pediococcus; Streptococcus; Tetrahydrofolates; Thioguanine | 1977 |
United States trials of adjuvant therapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Menopause; Methotrexate; Thiotepa | 1977 |
Acute skin reactions in postoperative breast cancer patients receiving radiotherapy plus adjuvant chemotherapy.
Topics: Breast Neoplasms; Cobalt Radioisotopes; Cyclophosphamide; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Radioisotope Teletherapy; Radiotherapy; Radiotherapy, High-Energy; Skin Diseases | 1978 |
Effects of antineoplastic drugs on Lactobacillus casei and radioisotopic assays for serum folate.
Topics: Antineoplastic Agents; Biological Assay; Drug Interactions; Fluorouracil; Folic Acid; Humans; Lacticaseibacillus casei; Methotrexate; Radioisotopes | 1978 |
Chemotherapy of common solid tumours in a general surgical unit.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Melanoma; Methotrexate; Middle Aged; Nausea; Neoplasms; Quality of Life; Vincristine; Vomiting | 1979 |
Pancreatitis during combination chemotherapy.
Topics: Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitomycins; Pancreatitis; Peritoneal Neoplasms; Vincristine | 1979 |
An in vitro assessment of the effect of cytotoxic drugs upon the intestinal absorption of nutrients in rats.
Topics: Animals; Ascorbic Acid; Biological Transport, Active; Fluorouracil; Glucose; Intestinal Absorption; Male; Methotrexate; Palmitic Acids; Rats; Tryptophan; Vitamin A | 1979 |
Chemotherapy for breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Vincristine | 1979 |
[Results of 5-fluorouracil, methotrexate, cyclophosphamide and prednisone combination therapy in the treatment of advanced breast cancer].
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Injections, Intravenous; Methotrexate; Middle Aged; Prednisone | 1979 |
5-drug adjuvant chemotherapy for breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Time Factors; Vincristine | 1979 |
[Effect of different dosages of chemotherapeutic agents on survival of mice with ascitic tumor (author's transl)].
Topics: Animals; Antineoplastic Agents; Bone Marrow; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Lymph Nodes; Male; Methotrexate; Mice; Neoplasms, Experimental | 1979 |
Variations in serum copper and ceruloplasmin levels in advanced gastrointestinal cancer treated with polychemotherapy.
Topics: Aged; Antineoplastic Agents; Ceruloplasmin; Colonic Neoplasms; Copper; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prognosis; Stomach Neoplasms | 1979 |
Potentiating role of previously administered agents in the combination chemotherapy of breast cancer.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prednisone; Vincristine | 1979 |
Enhanced 5-fluorouracil nucleotide formation after methotrexate administration: explanation for drug synergism.
Topics: Animals; Cells, Cultured; Drug Administration Schedule; Drug Synergism; Fluorouracil; Leukemia L1210; Methotrexate; Mice; Phosphoribosyl Pyrophosphate; Ribonucleotides; RNA, Neoplasm; Thymidylate Synthase | 1979 |
Adjuvant chemotherapy of breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Time Factors; Vincristine | 1979 |
[Comparison of the results of single-drug and combination chemotherapy of advanced ovarian cancer after 1 year].
Topics: Antineoplastic Agents; Dactinomycin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Melphalan; Methotrexate; Ovarian Neoplasms; Time Factors; Vincristine | 1979 |
[Efficiency and side effects of adriamycin-cyclophosphamide therapy compared to a triple combination of cyclophosphamide, methotrexate and 5-fluoro-uracil].
Topics: Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate | 1979 |
Combination chemotherapy for advanced pancreatic carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Vincristine | 1979 |
Effects of combination drug therapy on the subcutaneous and pulmonary growth of a slow and a fast-growing C3H/He mammary carcinoma.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Doxorubicin; Drug Resistance; Drug Therapy, Combination; Female; Fluorouracil; Lung Neoplasms; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mice, Inbred C3H; Soft Tissue Neoplasms; Time Factors | 1979 |
A well tolerated oral combination of chlorambucil (Leukeran R), methotrexate, fluorouracil, prednisone (LMFP) in disseminated breast cancer.
Topics: Aged; Antineoplastic Agents; Bone Marrow; Breast Neoplasms; Chlorambucil; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone | 1979 |
The cytocidal action of metronidazole in combination with other antineoplastic agents.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Hypoxia; Methotrexate; Metronidazole; Mice; Neoplasms, Experimental | 1979 |
Therapeutic manipulation of Nb rat prostatic adenocarcinomas: chemotherapeutic evaluation of autonomous tumors.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cyclophosphamide; Doxorubicin; Evaluation Studies as Topic; Fluorouracil; Male; Methotrexate; Neoplasm Transplantation; Prostatic Neoplasms; Rats; Rats, Inbred Strains | 1979 |
[Effect of the endolymphatic administration of chemical preparations on the leukocyte motor activity in stomach cancer].
Topics: Adult; Aged; Cell Movement; Drug Therapy, Combination; Female; Fluorouracil; Foot; Humans; Injections, Intralymphatic; Leukocytes; Male; Methotrexate; Middle Aged; Postoperative Period; Preoperative Care; Stomach Neoplasms; Time Factors | 1979 |
Complete remissions in metastatic breast cancer treated with combination drug therapy.
Topics: Adult; Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Castration; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Methotrexate; Middle Aged; Soft Tissue Neoplasms | 1979 |
The effect of combination chemotherapy on ovarian, hypothalamic and pituitary function in patients with breast cancer.
Topics: Adult; Amenorrhea; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follicle Stimulating Hormone; Humans; Hypothalamus; Luteinizing Hormone; Menopause; Menstruation Disturbances; Methotrexate; Middle Aged; Ovary; Pituitary Gland | 1979 |
Sequence for developing optimal combination chemotherapy of metastatic breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prednisone; Prospective Studies; Vincristine | 1979 |
Comparative study of in vivo development of resistance to various classes of antitumor agents in P388 leukemia.
Topics: Animals; Antimetabolites, Antineoplastic; Drug Resistance; Female; Fluorouracil; Leukemia P388; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Neoplasm Transplantation | 1979 |
Response to chemotherapy of breast carcinoma bone metastases: assessment by bone scan.
Topics: Adult; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Radionuclide Imaging | 1979 |
Effects of local tumor treatment with surgery or irradiation followed by adjuvant chemotherapy in mice--I. Survival of bone marrow stem cells.
Topics: Animals; Antineoplastic Agents; Cell Survival; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Hematopoietic Stem Cells; Male; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mice, Inbred CBA | 1979 |
In vitro sensitivity test of stomach cancer tissues by the use of metal grid method.
Topics: Antineoplastic Agents; Cytarabine; Drug Evaluation, Preclinical; Fluorouracil; Humans; In Vitro Techniques; Methotrexate; Mitomycins; Stomach Neoplasms; Thymidine | 1979 |
[Polychemotherapy in patients following radical surgery for bronchial carcinoma].
Topics: Bronchial Neoplasms; Busulfan; Cyclophosphamide; Drug Therapy, Combination; Drug Tolerance; Fluorouracil; Humans; Methotrexate; Postoperative Complications; Prognosis; Vinblastine | 1977 |
[Registration of cytostatic effects on cultured cells in vitro and their current significance for individualized chemotherapy of tumors in advanced ovarian carcinoma].
Topics: Acrylates; Antineoplastic Agents; Cells, Cultured; Cyclophosphamide; Female; Fluorouracil; Humans; In Vitro Techniques; Methotrexate; Ovarian Neoplasms; Time Factors; Vinblastine | 1977 |
[Drug information. Agents for treatment of neoplastic diseases. Therapeutic main group: cytostatic agents. 4].
Topics: Antimetabolites, Antineoplastic; Fluorouracil; Methotrexate | 1977 |
Drug interactions with antineoplastic agents.
Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Agents; Chloramphenicol; Cyclophosphamide; Drug Interactions; Drug Therapy, Combination; Fluorouracil; Humans; Mercaptopurine; Methotrexate; Mice; Neoplasms; Prednisolone; Rats; Thioguanine; Vinca Alkaloids | 1977 |
Heparin and polychemotherapy for treatment of lung cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Heparin; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Methotrexate; Middle Aged; Thioguanine; Vincristine | 1977 |
Adjuvant postoperative chemotherapy with 5-fluorouracil and methotrexate: effect of schedule of administration on metastasis of 13762 mammary adenocarcinoma.
Topics: Adenocarcinoma; Animals; BCG Vaccine; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Mammary Neoplasms, Experimental; Methotrexate; Neoplasm Metastasis; Rats | 1977 |
An in vitro method to determine the sensitivity of solid malignant tumours to cytostatic agents.
Topics: Antineoplastic Agents; Cells, Cultured; DNA Replication; Fluorouracil; Humans; Methotrexate; Neoplasms; Vincristine | 1977 |
Chemotherapy, immunotherapy and chemoimmunotherapy of colorectal cancer.
Topics: Colonic Neoplasms; Fluorouracil; Humans; Immunotherapy; Lomustine; Methotrexate; Mitomycins; Rectal Neoplasms | 1977 |
A basis for fluoropyrimidine-induced antagonism to methotrexate in Ehrlich ascites tumor cells in vitro.
Topics: Animals; Carcinoma, Ehrlich Tumor; Deoxyuridine; DNA, Neoplasm; Drug Therapy, Combination; Fluorouracil; In Vitro Techniques; Methotrexate; Mice; Pyrimidines; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymidine Monophosphate | 1978 |
5-fluorouracil and methotrexate sodium: an admixture incompatability?
Topics: Drug Combinations; Drug Incompatibility; Fluorouracil; Methotrexate | 1978 |
Recent trends in breast cancer treatment.
Topics: Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Hormones; Humans; Immunotherapy; Mastectomy; Melphalan; Methotrexate; Neoplasm Metastasis | 1978 |
Iatrogenic liver abscesses. A complication of hepatic artery ligation for tumor.
Topics: Arteriovenous Shunt, Surgical; Biliary Fistula; Bronchial Fistula; Female; Fluorouracil; Hepatic Artery; Humans; Iatrogenic Disease; Infusions, Intra-Arterial; Ligation; Liver Abscess; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Rupture, Spontaneous | 1978 |
Chemotherapy of ovarian cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms; Prednisolone; Remission, Spontaneous; Vincristine | 1978 |
[Pseudomyxoma of the peritoneum (author's transl)].
Topics: Ascites; Cystadenoma; Female; Fluorouracil; Humans; Hydrazines; Methotrexate; Middle Aged; Myxoma; Ovarian Neoplasms; Peritoneal Diseases; Podophyllin; Prednisolone | 1978 |
Chemotherapy trial with comp-F regimen in advanced adenocarcinoma of prostate.
Topics: Adenocarcinoma; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Male; Methotrexate; Neoplasm Metastasis; Prednisone; Prostatic Neoplasms; Retrospective Studies; Vincristine | 1978 |
[How could the results of surgical treatment of bronchogenic carcinoma be improved? (authors transl)].
Topics: Angiography; Carcinoma, Bronchogenic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Time; Vinblastine | 1978 |
[Breast neoplasms. Staging, therapy and after care].
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunotherapy; Mastectomy; Methotrexate; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Staging | 1978 |
Adriamycin in combination for the treatment of breast cancer: a Southwest Oncology Group study.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Middle Aged; Neoplasm Metastasis; Remission, Spontaneous; Time Factors | 1978 |
Rate of DNA synthesis as an indication of drug toxicity and as a guide for scheduling cancer therapy.
Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Lomustine; Methotrexate; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Thymidine | 1978 |
[Polychemotherapy of advanced cancer of the breast].
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Vincristine | 1978 |
A pilot study of sequential combination chemotherapy with adriamycin and cyclophosphamide, and methotrexate, 5-fluorouracil and prednisolone in advanced breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisolone | 1978 |
Combination chemotherapy for advanced breast cancer: two regimens containing adriamycin.
Topics: Adult; Aged; Antineoplastic Agents; Bone Marrow; Breast Neoplasms; Cyclophosphamide; Digestive System; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Remission, Spontaneous; Time Factors | 1978 |
Treatment of hepatic metastases from breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Remission, Spontaneous; Testosterone; Time Factors | 1978 |
[Resistance testing and chemotherapy results of bronchial tumours (author's transl)].
Topics: Bronchial Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Resistance; Fluorouracil; Humans; Hydroxyurea; Methotrexate; Prognosis; Remission, Spontaneous; Vincristine | 1978 |
Localized changes in blood-brain barrier permeability following the administration of antineoplastic drugs.
Topics: Albumins; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain; Capillaries; Cats; Cyclophosphamide; Evans Blue; Fluorouracil; Horseradish Peroxidase; Methotrexate; Time Factors; Vincristine | 1978 |
[Current state of therapy for gastrointestinal tumors].
Topics: Carmustine; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Humans; Methotrexate; Pancreatic Neoplasms; Prognosis; Remission, Spontaneous; Stomach Neoplasms; Vincristine | 1978 |
[Results of high-dosage attack treatment with cytostatics in mammary and ovarian cancer (author's transl)].
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Ovarian Neoplasms; Remission, Spontaneous; Vincristine | 1978 |
Malignant teratoma of the ovary: prognostic factors and treatment.
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms; Prognosis; Teratoma; Vincristine | 1978 |
Correlation of estrophilin content of primary mammary cancer to eventual endocrine treatment.
Topics: Adrenalectomy; Breast Neoplasms; Castration; Cyclophosphamide; Diethylstilbestrol; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Metastasis; Receptors, Estrogen; Remission, Spontaneous | 1978 |
[Combined irradiation and chemotherapy as postoperative treatment of breast cancer].
Topics: Aged; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate | 1978 |
[Complications of irradiation in combined irradiation and chemotherapy of breast cancer].
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Radiotherapy | 1978 |
Heterogeneity in drug sensitivity among tumor cell subpopulations of a single mammary tumor.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Cyclophosphamide; Drug Resistance; Fluorouracil; Male; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasm Metastasis; Remission, Spontaneous; Time Factors | 1978 |
Tuberculin and dinitrochlorobenzene (DNCB) tests in cancer patients before and after cytostatic drug therapy.
Topics: Cyclophosphamide; Dinitrochlorobenzene; Fluorouracil; Humans; Immunity, Cellular; Methotrexate; Neoplasms; Nitrobenzenes; Skin Tests; Tuberculin Test; Vinblastine | 1978 |
Effect of methylprednisolone on cell proliferation in C3H/HeJ spontaneous mammary tumors.
Topics: Animals; Cell Cycle; Cell Division; Drug Therapy, Combination; Female; Fluorouracil; Kinetics; Mammary Neoplasms, Experimental; Methotrexate; Methylprednisolone; Mice; Mice, Inbred C3H | 1978 |
Therapeutic consequences of antitumour drug interactions: methotrexate and 5-fluorouracil in the chemotherapy of C3H mice with transplanted mammary adenocarcinoma.
Topics: Adenocarcinoma; Animals; Drug Interactions; Drug Therapy, Combination; Female; Fluorouracil; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mice, Inbred C3H; Time Factors | 1978 |
Rationale of chemotherapeutic adjuvant treatment.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carmustine; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Humans; Leukemia L1210; Lomustine; Mercaptopurine; Methotrexate; Mice; Neoplasms | 1978 |
Actual data on efficacy of surgical adjuvant chemotherapy with CMF in breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate | 1978 |
In vitro effects of methotrexate, 5-fluorouracil, cyclophosphamide and vincristine sulphate on the metabolism of induced mammary cancers in rats.
Topics: Animals; Cyclophosphamide; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Fluorouracil; In Vitro Techniques; Mammary Neoplasms, Experimental; Methotrexate; Neoplasm Proteins; Rats; Thymidine; Vincristine | 1978 |
[Treatment of maxillary cancer].
Topics: Carubicin; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Maxillary Neoplasms; Methotrexate; Prospidium; Radioisotope Teletherapy; Vincristine | 1978 |
Further experience with chemotherapy in the Dunning prostatic adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Hybridization, Genetic; Hydroxyurea; Lomustine; Male; Methotrexate; Neoplasms, Experimental; Platinum; Prostatic Neoplasms; Rats | 1978 |
[Chemotherapy of inoperable endothoracic tumours (results of the Karrer and aco polycytostatic therapy) (author's transl)].
Topics: Adult; Aged; Bronchial Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Pyridoxine; Thoracic Neoplasms; Vinca Alkaloids; Vitamin B 12 | 1979 |
Chemoimmunotherapy of syngeneic mouse mammary carcinomas employing methanol extraction residue.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; BCG Vaccine; Cyclophosphamide; Female; Fluorouracil; Immunotherapy; Mammary Neoplasms, Experimental; Methanol; Methotrexate; Mice; Mice, Inbred BALB C; Mycobacterium bovis; Neoplasm Recurrence, Local; Solvents | 1976 |
Comparison of 5-fluorouracil and ftorafur. II. Therapeutic response and development of resistance in murine tumors.
Topics: Animals; Carcinoma; Cell Line; Drug Resistance; Drug Therapy, Combination; Female; Fluorouracil; Leukemia L1210; Leukemia, Experimental; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Melanoma; Methotrexate; Mice; Neoplasms, Experimental; Tegafur | 1976 |
Vitamin B12 levels in drug-treated bacterial cells.
Topics: Bacillus megaterium; Chloramphenicol; Dactinomycin; Dose-Response Relationship, Drug; Fluorouracil; Methotrexate; Puromycin; Sulfathiazoles; Vitamin B 12 | 1975 |
Fresh explant culture of human tumours in vitro and the assessment of sensitivity to cytotoxic chemotherapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Culture Techniques; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Kidney Neoplasms; Melanoma; Methotrexate; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Ovarian Neoplasms; Thiotepa; Vincristine | 1975 |
Immunological overshoot phenomenon following cancer chemotherapy: significance in prognosis evaluation of solid tumors.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immune Adherence Reaction; Liver Neoplasms; Lung Neoplasms; Lymphocyte Activation; Melphalan; Methotrexate; Neoplasms; Ovarian Neoplasms; Thiotepa; Vincristine | 1975 |
[Endolymphatic polychemotherapy of cancer of the ovaries].
Topics: Adult; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms; Thiotepa | 1975 |
[Chemotherapy of bronchial carcinomas (author's transl)].
Topics: Antineoplastic Agents; Bronchial Neoplasms; Carcinoma, Bronchogenic; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Long-Term Care; Lung Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Retrospective Studies; Vinblastine | 1975 |
Use of the dog spleen for studying effects of irradiation and chemotherapeutic agents, with suggested uses of other organs.
Topics: Animals; Antineoplastic Agents; Azathioprine; Cyclophosphamide; Dogs; Fluorouracil; Leukocytes; Mechlorethamine; Methotrexate; Pneumococcal Infections; Prednisolone; Radiation Dosage; Radiation Effects; Spleen; Thiotepa; Time Factors; Vinblastine | 1976 |
Intraprostatic Injections of various antitumour compounds into rats: Part II. Chronic effects.
Topics: Animals; Antineoplastic Agents; Dactinomycin; Fluorouracil; Injections; Male; Methotrexate; Mitomycins; Prostate; Rats; Thiotepa; Time Factors | 1976 |
[Endolymphatic chemotherapy of cervix neoplasms].
Topics: Antineoplastic Agents; Cyclophosphamide; Female; Fluorouracil; Humans; Infusions, Parenteral; Injections, Intralymphatic; Methotrexate; Middle Aged; Thiotepa; Uterine Cervical Neoplasms | 1976 |
Psoriasis: clinical aspects and management.
Topics: Administration, Topical; Age Factors; Azauridine; Fluorouracil; Humans; Hydroxyurea; Mechlorethamine; Methotrexate; Methoxsalen; Nitrosourea Compounds; Psoriasis; Thiotepa; Triamcinolone Acetonide | 1976 |
Schedule-dependent antitumor effects of methotrexate and 5-fluorouracil.
Topics: Animals; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Methotrexate; Mice; Sarcoma 180; Time Factors | 1977 |
Bone marrow involvement in breast cancer: effect on response and tolerance to combination chemotherapy.
Topics: Adult; Aged; Blood Cell Count; Blood Platelets; Bone Marrow Diseases; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Remission, Spontaneous | 1977 |
Combination chemotherapy using cyclophosphamide, vincristine, methotrexate, 5-fluorouracil, and prednisone in solid tumors.
Topics: Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Leukocyte Count; Lung Neoplasms; Male; Methotrexate; Neoplasms; Ovarian Neoplasms; Prednisone; Remission, Spontaneous; Time Factors; Vincristine | 1977 |
[Local and intravenous cytostatic therapy after surgery of malignant brain tumors].
Topics: Administration, Topical; Brain Neoplasms; Cyclophosphamide; Female; Fluorouracil; Glioma; Humans; Injections, Intravenous; Male; Methotrexate; Vincristine | 1977 |
Systemic therapy for metastatic breast cancer.
Topics: BCG Vaccine; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Estrogens; Female; Fluorouracil; Humans; Immunotherapy; Mastectomy; Methotrexate; Neoplasm Metastasis; Prednisone; Propionibacterium acnes; Receptors, Estrogen; Triiodothyronine | 1977 |
Genetical and biochemical evidence that a novel dinucleoside polyphosphate coordinates salvage and de novo nucleotide biosynthetic pathways in mammalian cells.
Topics: Azaserine; Cell Line; Fluorouracil; Genes; Glutamine; Guanosine Triphosphate; Methotrexate; Mutation; Oligonucleotides; Oligoribonucleotides; Ribonucleotides | 1977 |
[Combination cytostatic chemotherapy of advanced metastatic cancer of the prostate. A preliminary uncontrolled study].
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Bone Marrow Diseases; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms; Time Factors; Vincristine | 1977 |
Multiple drug chemotherapy regimen for patients with hormonally-unresponsive carcinoma of the prostate: a preliminary report.
Topics: Administration, Oral; Antineoplastic Agents; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Estrogens; Fluorouracil; Follow-Up Studies; Humans; Injections, Intravenous; Male; Melphalan; Methotrexate; Neoplasm Metastasis; Prednisone; Prostatic Neoplasms; Vincristine | 1977 |
[Chemotherapy of breast cancers].
Topics: Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis | 1977 |
[Case report of a Gartner's duct carcinoma of the vagina (author's transl)].
Topics: Adult; Antineoplastic Agents; Carcinoembryonic Antigen; Cyclophosphamide; Female; Fluorouracil; Humans; Mercaptopurine; Mesonephroma; Methotrexate; Vaginal Neoplasms | 1977 |
Quadruple chemotherapy in the treatment of advanced or recurrent gastrointestinal carcinoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Methotrexate; Middle Aged; Recurrence; Remission, Spontaneous; Time Factors; Vincristine | 1977 |
Adjuvant treatment of cancer. II. Breast carcinoma.
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Prednisone; Vincristine | 1977 |
[Differential therapy of advanced bladder carcinoma and of postoperative adjuvant chemotherapy (author's transl)].
Topics: Antineoplastic Agents; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Iliac Artery; Injections, Intra-Arterial; Injections, Intravenous; Methotrexate; Postoperative Care; Urinary Bladder Neoplasms; Vinblastine | 1977 |
Adjuvant combination chemotherapy with CMF in primary mammary carcinoma.
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged | 1977 |
DNA synthesis in isolated lymphocyte nuclei. Effects of megaloblastic anaemia due to folate or vitamin B-12 deficiency or antimetabolite drugs.
Topics: Adenosine Triphosphate; Adult; Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Cell Nucleus; Cytarabine; DNA; DNA Replication; DNA-Directed DNA Polymerase; Ethylmaleimide; Female; Fluorouracil; Folic Acid Deficiency; Humans; Hydroxyurea; Kinetics; Lectins; Lymphocyte Activation; Lymphocytes; Male; Methotrexate; Middle Aged; Thymine Nucleotides; Vitamin B 12 Deficiency | 1977 |
Cyclic combination chemotherapy for metastatic breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Remission, Spontaneous | 1977 |
[Polychemotherapy in advanced tumor of the breast. Our preliminary results].
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Combinations; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Postoperative Care; Vincristine | 1977 |
Quadruple chemotherapy for advanced malignant disease.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasms; Remission, Spontaneous; Stomach Neoplasms; Vincristine | 1977 |
Therapy of primary breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Menopause; Methotrexate; Postoperative Care; Prednisone; Vincristine | 1977 |
Alteration in nail pigment after chemotherapy.
Topics: Antineoplastic Agents; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Nails; Pigmentation Disorders | 1977 |
Enhancement and inhibition of mammary tumor formation and growth by cytostatic drugs.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Female; Fluorouracil; Mammary Neoplasms, Experimental; Melphalan; Methotrexate; Mice; Mice, Inbred BALB C; Precancerous Conditions; Prednisone; Vincristine | 1977 |
[Cytostatic pneumopathy following chemotherapy for metastasizing breast neoplasm].
Topics: Aged; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Ethinyl Estradiol; Female; Femoral Vein; Fluorouracil; Humans; Lung Diseases; Methotrexate; Prednisone; Pulmonary Alveoli; Pulmonary Fibrosis; Thrombophlebitis; Vincristine | 1977 |
Grand Rounds: Adjuvant therapy of breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged | 1977 |
Indication of antitumor agents by microbiologic methods.
Topics: Animals; Antineoplastic Agents; Bacteria; Biological Assay; Female; Fluorouracil; Humans; Kinetics; Male; Methotrexate; Neoplasms | 1977 |
Pharmacokinetic considerations in the design of optimal chemotherapeutic regimens for the treatment of breast carcinoma: a comceptual approach.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Cytarabine; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intravenous; Methotrexate; Research Design; Vincristine | 1976 |
Outpatient chemotherapy of advanced breast cancer in a community setting: a five-drug regimen.
Topics: Adult; Aged; Ambulatory Care; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Georgia; Humans; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Vincristine | 1976 |
Combination chemotherapy with 4'Demethylepipodophyllotoxin 9-(4,6-0-ethylidene-beta-D-glucopyranoside), VP 16-213 (NSC 141540) in L1210 leukemia.
Topics: Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Leukemia L1210; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred DBA; Podophyllotoxin; Vincristine | 1976 |
[Side effects of cytostatic therapy in childhood].
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Female; Fluorouracil; Humans; Male; Mannitol; Mercaptopurine; Methotrexate; Prednisone; Procarbazine; Time Factors; Triaziquone; Vinblastine; Vincristine | 1976 |
[In vitro and in vivo experiments on the immunosuppressive properties of cytostatic substances (author's transl)].
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dermatitis, Contact; Fluorouracil; Guinea Pigs; Immunosuppression Therapy; In Vitro Techniques; Lymphocyte Activation; Methotrexate; Vincristine | 1976 |
[Polychemotherapy of the advanced and metastasizing carcinoma of the breast].
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Neoplasm Metastasis; Remission, Spontaneous; Time Factors; Vinblastine | 1976 |
[Five-drug therapy in addition to hormonal treatment in advance breast cancer metastatic to the lung (author's transl)].
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Gonadal Steroid Hormones; Humans; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Remission, Spontaneous; Retrospective Studies; Time Factors; Vincristine | 1976 |
[Experiences with cytostatic treatment of malignant tumors].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Neoplasms; Prednisone; Sarcoma; Stomach Neoplasms; Triaziquone; Vincristine | 1976 |
[Late results of lung cancer therapy (according to material from the Kazakh Scientific Research Institute of Oncology and Radiology)].
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Fluorouracil; Follow-Up Studies; Humans; Lung Neoplasms; Methotrexate | 1976 |
Compatibility of antineoplastic, antibiotic and corticosteroid drugs in intravenous admixtures.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Cytarabine; Drug Incompatibility; Fluorouracil; Injections, Intravenous; Methotrexate; Prednisolone; Vincristine | 1976 |
[Preliminary experiences in the treatment of metastatic mamma carcinoma by polychemotherapy-according to Cooper (author's transl)].
Topics: Breast Neoplasms; Cyclophosphamide; Drug Combinations; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prednisone; Remission, Spontaneous; Vincristine | 1976 |
[Cytostatic therapy of inoperable carcinomas].
Topics: Breast Neoplasms; Bronchial Neoplasms; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Pregnancy; Procarbazine; Testicular Neoplasms; Vinblastine; Vincristine | 1976 |
Phase II trial of 5-fluorouracil (NSC-19893), adriamycin (NSC-123127), and methotrexate (NSC-740) in lung adenocarcinoma.
Topics: Adenocarcinoma; Antineoplastic Agents; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Remission, Spontaneous | 1976 |
Combination chemotherapy in the treatment of advanced breast cancer.
Topics: Adrenalectomy; Alopecia; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prednisone; Vincristine | 1976 |
Serial carcinoembryonic antigen assays in patients with metastatic carcinoma of prostate being treated with chemotherapy.
Topics: Acid Phosphatase; Adenocarcinoma; Carcinoembryonic Antigen; Drug Therapy, Combination; Fluorouracil; Humans; Male; Melphalan; Methotrexate; Neoplasm Metastasis; Prednisone; Prostatic Neoplasms; Vincristine | 1976 |
Clinical chemistry and breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Melphalan; Methotrexate; Neoplasm Recurrence, Local; Risk | 1976 |
Deveopment of resistance to combinations of six antimetabolites in mice with L1210 leukemia.
Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Fluorouracil; Leukemia L1210; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Thioguanine; Thioinosine | 1976 |
Multidisciplinary curative treatment for disseminated carcinoma of the breast.
Topics: Androgens; Antineoplastic Agents; Breast Neoplasms; Castration; Cyclophosphamide; Diethylstilbestrol; Drug Therapy, Combination; Ethinyl Estradiol; Female; Fluorouracil; Humans; Medroxyprogesterone; Methotrexate; Neoplasm Metastasis; Remission, Spontaneous; Thoracic Neoplasms; Vincristine | 1976 |
"Early" and "late" breast cancer: a unified concept for treatment.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Hypophysectomy; Methotrexate; Neoplasm Metastasis; Norethindrone; Time Factors; Vincristine | 1976 |
Screening of cytotoxic drugs for residual bone marrow damage.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Diseases; Busulfan; Carmustine; Cell Survival; Cyclophosphamide; Drug Evaluation, Preclinical; Female; Fluorouracil; Hematopoietic Stem Cells; Mercaptopurine; Methotrexate; Mice; Mice, Inbred BALB C; Vinblastine | 1976 |
[Chemotherapy of inoperable breast cancer with a combination of 5-fluorouracil, methotrexate, vincristine, cyclophosphamide and prednisolone].
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisolone; Vincristine | 1976 |
[Chemotherapy in primary and metastatic intrathoracic cancer].
Topics: Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Lomustine; Methotrexate; Neoplasm Metastasis; Remission, Spontaneous; Thoracic Neoplasms; Vincristine | 1976 |
Thymidine kinase in megaloblastic anaemia.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Female; Fluorouracil; Folic Acid; Folic Acid Deficiency; Humans; Lectins; Lymphocyte Activation; Male; Methotrexate; Puromycin; Sonication; Thymidine Kinase; Vitamin B 12; Vitamin B 12 Deficiency | 1976 |
The role of chemotherapy in the treatment of breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Methotrexate; Prognosis; Time Factors | 1976 |
The role of nonspecific immunotherapy in the treatment of breast cancer.
Topics: Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunity; Immunity, Cellular; Immunotherapy; Liver Neoplasms; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Prognosis; Propionibacterium acnes | 1976 |
Current overview of EORTC clinical trials with tamoxifen.
Topics: Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Menopause; Menstruation; Methotrexate; Stilbenes; Tamoxifen; Vincristine | 1976 |
Concomitant androgen therapy in the management of advanced breast cancer by cyclical combined chemotherapy.
Topics: Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Hemoglobins; Humans; Methotrexate; Nandrolone; Neoplasm Metastasis; Oxymetholone; Vincristine | 1976 |
Kinetic aids to proper chemotherapeutic scheduling: labeled nucleoside incorporation studies in vivo.
Topics: Animals; Bone Marrow; Cell Survival; Cyclophosphamide; DNA, Neoplasm; Drug Administration Schedule; Fluorouracil; Granulocytes; Intestinal Mucosa; Kinetics; Lomustine; Male; Melanoma; Methotrexate; Mice; Neoplasms, Experimental; Pyrimidine Nucleosides; Thymidine; Uridine | 1976 |
[Five years treatment of advanced solid malignomas with a combination of four cytostatic drugs (author's transl)].
Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasms; Ovarian Neoplasms; Sarcoma; Urinary Bladder Neoplasms; Vinblastine | 1976 |
Combination chemotherapy for disseminated carcinoma of the breast.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Vincristine | 1975 |
Experimental and clinical studies on nucleoside analogs as antitumor agents.
Topics: Aged; Animals; Cytarabine; Drug Resistance; Flucytosine; Fluorouracil; Humans; Leukemia L1210; Leukemia, Experimental; Male; Methotrexate; Mice; Nasopharyngeal Neoplasms; Structure-Activity Relationship | 1975 |
Adjuvant treatment in operable breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate | 1976 |
Chemotherapy and breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Levamisole; Methotrexate | 1976 |
The results of surgical treatment combined with intra-arterial infusion of anti-cancer agents in osteosarcoma.
Topics: Adolescent; Adult; Bone Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Child; Extremities; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Male; Methotrexate; Mitomycins; Osteosarcoma | 1976 |
Effect of cytostatic drugs on nucleic acid synthesis in mouse thymocytes and chick embryo cells.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Chick Embryo; Cytarabine; Dactinomycin; Deoxyadenosines; Deoxyuridine; DNA; Fluorouracil; Melphalan; Methotrexate; Mice; Mice, Inbred Strains; Thymidine; Thymus Gland; Triaziquone; Tritium; Uridine; Vinblastine | 1975 |
Combined chemotherapy and cryosurgery for oral cancer.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cryosurgery; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Male; Methods; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Recurrence, Local; Ohio; Tongue Neoplasms | 1975 |
Offsetting toxicity of antineoplastic agents.
Topics: Animals; Biological Products; Bone Marrow; Bone Marrow Cells; Carcinoma, Krebs 2; Cells, Cultured; Fluorouracil; Leukemia L1210; Methotrexate; Mice; Mitosis; Saccharomyces cerevisiae | 1975 |
Hepatic artery ligation in treatment of carcinoid syndrome.
Topics: Aged; Angiography; Cyclophosphamide; Female; Fluorouracil; Hepatic Artery; Humans; Hydroxyindoleacetic Acid; Ileum; Intestinal Neoplasms; Ligation; Liver Neoplasms; Malignant Carcinoid Syndrome; Methotrexate; Neoplasm Metastasis; Radionuclide Imaging; Serum Albumin, Radio-Iodinated | 1975 |
Chemotherapy of breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasm Metastasis; Prednisone; Prognosis; Vincristine | 1975 |
Changes in 87mSr concentractions in skeletal metastases in patients responding to cyclical combination chemotherapy for advanced breast cancer.
Topics: Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Radionuclide Imaging; Strontium Isotopes; Vincristine | 1975 |
An effective low-dose intermittent cyclophosphamide, methotrexate, and 5-fluorouracil treatment regimen for metastatic breast cancer.
Topics: Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Neoplasm Metastasis; Peritoneal Neoplasms; Pleural Neoplasms; Skin Neoplasms | 1975 |
Adriamycin plus vincristine compared to and combined with cyclophosphamide, methotrexate, and 5-fluorouracil for advanced breast cancer.
Topics: Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Remission, Spontaneous; Vincristine | 1975 |
Systemic chemotherapy of advanced head and neck malignancies.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Imidazoles; Melanoma; Methotrexate; Neoplasms; Nitrosourea Compounds; Retrospective Studies; Sarcoma; Triazenes; Vincristine | 1975 |
Interaction of chemotherapeutic agents with methotrexate and 5-fluorouracil and its effect on de novo DNA synthesis.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cephalosporins; Dexamethasone; DNA; DNA, Neoplasm; Fluorouracil; Folic Acid; Glucocorticoids; Humans; Hydrocortisone; Idoxuridine; In Vitro Techniques; Leukemia L1210; Methotrexate; Mice; Mice, Inbred DBA; Prednisolone; Prednisone; Vincristine | 1975 |
Symposium on breast carcinoma.
Topics: Adrenalectomy; Age Factors; Androgens; Antineoplastic Agents; Breast Neoplasms; Castration; Cyclophosphamide; Doxorubicin; Estrogens; Female; Fluorouracil; Gonadal Steroid Hormones; Humans; Hypophysectomy; Methotrexate; Vinca Alkaloids | 1975 |
Letter: Combination chemotherapy for breast cancer.
Topics: Bone Marrow; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver; Methotrexate; Prednisone | 1975 |
[Possibilities and limits of pre-therapeutic neoplasm sensitivity cytostatics tests under short-term conditions].
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cricetinae; Cyclophosphamide; Dactinomycin; Daunorubicin; Disease Models, Animal; DNA, Neoplasm; Doxorubicin; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Hydroxyurea; Male; Methotrexate; Mice; Procarbazine; Rats; RNA, Neoplasm; Time Factors; Triaziquone; Vincristine | 1975 |
[Chemotherapeutic combinations of mutually potentializing drugs. 1-Application to the treatment of breast cancers].
Topics: Aged; Alopecia; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neurologic Manifestations; Nitrosourea Compounds; Podophyllotoxin; Vincristine; Vomiting | 1975 |
[Conservative treatment of lung cancer].
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Radioisotope Teletherapy; Radiotherapy Dosage; Ukraine; Vinblastine | 1975 |
Letter: drugs for common cancers.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Vincristine | 1975 |
Changes of the immunogenic properties of a radiation-induced mouse lymphoma following treatment with antitumor drugs.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Cyclophosphamide; Dacarbazine; Fluorouracil; Histocompatibility Antigens; Immunity; Lymphoma; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Nitrosourea Compounds; Pyrazoles; Thioguanine; Transplantation Immunology; Transplantation, Homologous; X-Rays | 1975 |
Combination chemotherapy in metastatic carcinoma of the breast. Results with a three-drug combination.
Topics: Adenocarcinoma; Adult; Aged; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Ethylnitrosourea; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis | 1975 |
Chemotherapy in the treatment strategy of breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prednisone | 1975 |
The effect of cytostatic drugs on the synthesis of DNA in adenocarcinomas of the stomach. An in vitro study.
Topics: Adenocarcinoma; Antineoplastic Agents; Cells, Cultured; Depression, Chemical; DNA, Neoplasm; Fluorouracil; Humans; In Vitro Techniques; Melphalan; Methotrexate; Stomach Neoplasms; Thymidine; Tritium; Uridine; Vinblastine | 1975 |
Intra arterial chemotherapy in malignant tumours of liver (a preliminary report).
Topics: Female; Fluorouracil; Hepatic Artery; Humans; Injections, Intra-Arterial; Liver Neoplasms; Methotrexate; Mitomycins | 1975 |
Comparison of 5-fluorouracil with 5-fluorouracil, cyclophosphamide, and methotrexate in metastatic colorectal carcinoma.
Topics: Colonic Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms | 1975 |
Heterogeneity of human adenocarcinomas of the colon and the stomach as regards sensitivity to cytostatic drugs.
Topics: Adenocarcinoma; Antineoplastic Agents; Colonic Neoplasms; Cytarabine; Fluorouracil; Humans; Melphalan; Methotrexate; Stomach Neoplasms; Vinblastine | 1975 |
Heparin and chemotherapy in the management of inoperable lung carcinoma.
Topics: Adult; Aged; Cyclophosphamide; Drug Tolerance; Female; Fluorouracil; Heparin; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Thioguanine; Vincristine | 1975 |
[Cell cycle and carcinochemotherapy: reality or hope? (author's transl)].
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cyclophosphamide; Drug Therapy, Combination; Dysgerminoma; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms; Prednisone; Vincristine | 1975 |
Enzyme kinetics and combination chemotherapy: an appraisal of current concepts.
Topics: Antimetabolites; Cell Line; Cell-Free System; Cells, Cultured; Drug Therapy, Combination; Enzyme Inhibitors; Enzymes; Fluorodeoxyuridylate; Fluorouracil; Folic Acid Antagonists; Kinetics; Macromolecular Substances; Methotrexate; Models, Biological | 1975 |
[Tele-gamma irradiation and regional chemotherapy in the treatment of patients with widespread head and neck tumours (author's transl)].
Topics: Adolescent; Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radioisotope Teletherapy | 1975 |
Combination chemotherapy.
Topics: Adult; Antineoplastic Agents; Child; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Prednisone; Procarbazine; Vincristine | 1975 |
[1st report on programmed chemotherapy of ovarian carcinoma].
Topics: Adenocarcinoma; Antineoplastic Agents; Cyclophosphamide; Cystadenocarcinoma; Cystadenoma; Drug Therapy, Combination; Endometriosis; Female; Fluorouracil; Follow-Up Studies; Granulosa Cell Tumor; Humans; Methotrexate; Ovarian Neoplasms; Time Factors; Vincristine | 1975 |
Combination chemotherapy as an adjuvant treatment in operable breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Recurrence; Time Factors | 1976 |
Editorial: Major advance in breast-cancer therapy.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Methotrexate; Neoplasm Metastasis; Prednisone; Time Factors; Vincristine | 1976 |
Combination chemotherapy for advanced breast cancer: response and effect on survival.
Topics: Adult; Bone Neoplasms; Breast Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Skin Neoplasms | 1976 |
Chemotherapy of malignant diffuse mesothelioma.
Topics: Aged; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Mesothelioma; Methotrexate; Middle Aged; Peritoneal Neoplasms; Pleural Neoplasms; Remission, Spontaneous; Vincristine | 1976 |
Letter: Chemotherapy of breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate | 1976 |
New attitudes in cancer treatment: breast cancer and adjuvant therapy.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Recurrence, Local | 1976 |
The effect of Corynebacterium parvum in combination with 5-fluorouracil, L-phenylalanine mustard, or methotrexate on the inhibition of tumor growth.
Topics: Animals; Cell Division; Cyclophosphamide; Drug Synergism; Female; Fluorouracil; Immunotherapy; Mammary Neoplasms, Experimental; Melphalan; Methotrexate; Mice; Mice, Inbred C3H; Propionibacterium acnes | 1976 |
The sensitivities of human and murine hemopoietic cells exposed to cytotoxic drugs in an in vivo culture system.
Topics: Agar; Animals; Antineoplastic Agents; Cells, Cultured; Cyclophosphamide; Diffusion; Dose-Response Relationship, Drug; Fluorouracil; Hematopoietic Stem Cells; Humans; Male; Methotrexate; Mice; Vinblastine | 1976 |
Chemosensitivity of head and neck cancer with the rapid thymidine incorporation assay and its clinical application.
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Child; Cisplatin; Colonic Neoplasms; DNA, Neoplasm; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Mitomycins; Peplomycin; Remission Induction; Stomach Neoplasms; Thymidine; Tritium; Tumor Cells, Cultured | 1992 |
[Chemosensitivity testing of adenocystic tongue and gingival cancer cell lines].
Topics: Antineoplastic Agents; Cystadenocarcinoma; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Gingival Neoplasms; Humans; Methotrexate; Tongue Neoplasms; Tumor Cells, Cultured | 1992 |
Sequential MTX-5 FU chemotherapy in pallination of advanced cancer cervix.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Uterine Cervical Neoplasms | 1992 |
[Prognostic and therapeutic significance of steroid receptors in invasive breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Node Excision; Mastectomy, Simple; Methotrexate; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Receptors, Progesterone; Survival Analysis; Survival Rate; Tamoxifen | 1992 |
Adjuvant therapy for primary breast cancer in a female patient affected by autoimmune liver disease: does it cure breast cancer and primary biliary cirrhosis?
Topics: Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Liver Cirrhosis, Biliary; Liver Function Tests; Methotrexate; Middle Aged | 1992 |
Chemosensitivity of salivary gland and oral cancer cell lines.
Topics: Cantharidin; Doxorubicin; Fluorouracil; Humans; Methotrexate; Mouth Neoplasms; Salivary Gland Neoplasms; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1992 |
[The efficacy of polychemotherapy with cisplatin, methotrexate and 5-fluorouracil in inoperable forms of squamous cell cancer of the head and neck area].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Time Factors | 1992 |
[Sequential MTX and 5-FU therapy of gastric cancer with systemic bone metastasis and disseminated intravascular coagulation].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Disseminated Intravascular Coagulation; Drug Administration Schedule; Female; Fluorouracil; Gabexate; Heparin; Humans; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 1992 |
Adjuvant chemotherapy in high-risk breast cancer patients with ten or more positive lymph nodes.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leucovorin; Lymphatic Metastasis; Methotrexate; Middle Aged; Vinblastine | 1992 |
[Chromosomal restructurings and the distribution of chromosome fragile sites in the peripheral blood lymphocytes in a breast cancer patient after cytostatic therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Chromosome Aberrations; Chromosome Fragile Sites; Chromosome Fragility; Combined Modality Therapy; Female; Fluorouracil; Humans; Lymphocytes; Methotrexate; Middle Aged; Ring Chromosomes; Tamoxifen; Time Factors | 1992 |
Comparison of partial and modified radical mastectomy in the community setting--"10 years later".
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Lymphatic Metastasis; Mastectomy, Modified Radical; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Survival Rate | 1992 |
Orofacial complications of chemotherapy for breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Candidiasis, Oral; Chi-Square Distribution; Cohort Studies; Cyclophosphamide; Facial Pain; Female; Fluorouracil; Humans; Immunosuppressive Agents; Methotrexate; Middle Aged; Mouth Mucosa; Peripheral Nervous System Diseases; Prednisone; Prospective Studies; Stomatitis; Surveys and Questionnaires; Vincristine | 1992 |
Continuous-infusion cisplatin, 5-fluorouracil, and bolus methotrexate in the treatment of advanced non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Female; Fluorouracil; Humans; Infusions, Intravenous; Injections, Intravenous; Lung Neoplasms; Male; Methotrexate; Middle Aged; Survival Analysis | 1992 |
Activities of thymidylate synthetase and thymidine kinase in gastric cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Linear Models; Male; Methotrexate; Stomach; Stomach Neoplasms; Thymidine Kinase; Thymidylate Synthase | 1992 |
Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy. 133 randomised trials involving 31,000 recurrences and 24,000 deaths among 75,000 women. Early Breast Cancer Trialists' Collaborative Group.
Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Global Health; Humans; Immunotherapy; Methotrexate; Middle Aged; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Ovariectomy; Randomized Controlled Trials as Topic; Survival Analysis; Tamoxifen; Time Factors; Treatment Outcome | 1992 |
Pseudomembranous colitis complicating chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Enterocolitis, Pseudomembranous; Female; Fluorouracil; Humans; Methotrexate | 1992 |
Mobilization of peripheral blood progenitor cells by chemotherapy and granulocyte-macrophage colony-stimulating factor for hematologic support after high-dose intensification for breast cancer.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Component Transfusion; Bone Marrow Transplantation; Breast Neoplasms; Carboplatin; Colony-Forming Units Assay; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Hematopoietic Stem Cell Transplantation; Humans; Macrophages; Methotrexate; Middle Aged; Neoplasm Metastasis; Thiotepa | 1992 |
Financial considerations in the use of adjuvant chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Survival Rate | 1992 |
[Experimental study of CF chemotherapy, combined with another one chemotherapeutic drug against head and neck cancer cell lines].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Peplomycin; Tumor Cells, Cultured; Vincristine | 1992 |
Leucovorin enhances cytotoxicity of trimetrexate/fluorouracil, but not methotrexate/fluorouracil, in CCRF-CEM cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Fluorouracil; Humans; Leucovorin; Leukemia, Lymphoid; Methotrexate; Phosphoribosyl Pyrophosphate; Trimetrexate; Tumor Cells, Cultured | 1992 |
Adjuvant cytostatic therapy of breast cancer as an important factor in the postponing of a relapse and longer survival period.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Survival Rate | 1992 |
Nonresectable adenocarcinoma of the rectum assessed by MR imaging before and after chemotherapy and irradiation.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouracil; Humans; Leucovorin; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness; Rectal Neoplasms | 1992 |
Proportional hazards and recursive partitioning and amalgamation analyses of the Southwest Oncology Group node-positive adjuvant CMFVP breast cancer data base: a pilot study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Multivariate Analysis; Prednisone; Proportional Hazards Models; Receptors, Estrogen; Receptors, Progesterone; Survival Rate; Vincristine | 1992 |
Time dependence of DNA lesions and growth inhibition by ICI D1694, a new quinazoline antifolate thymidylate synthase inhibitor.
Topics: Cell Division; Cell Line; DNA; DNA Damage; DNA, Single-Stranded; Fluorouracil; Formyltetrahydrofolates; Methotrexate; Quinazolines; Rhodamines; Thiophenes; Thymidine; Thymidylate Synthase; Time Factors | 1992 |
Occupational exposure to antineoplastic agents at several departments in a hospital. Environmental contamination and excretion of cyclophosphamide and ifosfamide in urine of exposed workers.
Topics: Air Pollutants, Occupational; Antineoplastic Agents; Cyclophosphamide; Environmental Monitoring; Environmental Pollutants; Female; Fluorouracil; Hospital Departments; Humans; Ifosfamide; Methotrexate; Nurses; Occupational Exposure; Pharmacy Technicians | 1992 |
Salvage chemotherapy in colorectal cancer patients with good performance status and young age after failure of 5-fluorouracil/leucovorin combination.
Topics: Adenocarcinoma; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Salvage Therapy; Survival Rate; Vincristine | 1992 |
Surgery for local recurrences following deficient radical mastectomy for breast cancer: a selected series of 39 cases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy, Radical; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Reoperation | 1992 |
Neoadjuvant chemotherapy in the treatment of recurrent glioblastomas (GBM).
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Fluorouracil; Glioma; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Reoperation | 1992 |
Metastatic breast cancer: higher versus low dose maintenance treatment when only a partial response or a no change status is obtained following doxorubicin induction treatment. An Eastern Cooperative Oncology Group study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Fluoxymesterone; Humans; Methotrexate; Mitolactol; Neoplasm Recurrence, Local; Prednisone; Prospective Studies; Remission Induction; Survival Rate; Tamoxifen | 1992 |
Fluorouracil catabolism in the combination treatment of cyclophosphamide, methotrexate and fluorouracil.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Drug Interactions; Female; Fluorouracil; Injections, Intravenous; Methotrexate; Rats; Rats, Inbred Strains | 1992 |
Chemotherapy-induced amenorrhea and other clinical and pathological parameters in the prognosis of breast cancer patients.
Topics: Adult; Amenorrhea; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Multivariate Analysis; Ovary; Prognosis; Retrospective Studies | 1992 |
Breast cancer: adjuvant therapy with anthracyclines.
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Fluorouracil; Humans; Methotrexate | 1992 |
A case of linitis plastica of the rectum treated by pelvic exenteration after aggressive immunochemotherapy.
Topics: Adult; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intra-Arterial; Injections, Intradermal; Injections, Intralesional; Linitis Plastica; Male; Methotrexate; Pelvic Exenteration; Picibanil; Rectal Neoplasms | 1992 |
Chemotherapy of solid tumors in private practice in Malaysia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Drug Administration Schedule; Epirubicin; Fluorouracil; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Malaysia; Methotrexate; Mitomycin; Nasopharyngeal Neoplasms; Neoplasms; Private Practice | 1992 |
Fatal systemic candidiasis of gastrointestinal origin: an experimental model in mice compromised by anti-cancer treatment.
Topics: Animals; Candida albicans; Candidiasis; Cecum; Chemotherapy, Adjuvant; Disease Models, Animal; Esophagus; Female; Fluorouracil; Follow-Up Studies; Gastrointestinal Diseases; Immunocompromised Host; Intestines; Liver; Methotrexate; Mice; Mice, Inbred ICR; Neoplasms; Stomach; Viscera | 1992 |
Endocrine function in premenopausal and postmenopausal advanced breast cancer patients treated with CMF or tamoxifen.
Topics: Adult; Aged; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Endocrine Glands; Estradiol; Female; Fluorouracil; Gonadotropins; Humans; Menopause; Methotrexate; Middle Aged; Ovary; Pituitary Gland; Progesterone; Prolactin; Tamoxifen; Testosterone | 1992 |
[Evaluation of radiation therapy combined with intra-arterial infusion chemotherapy in patients with non-resectable pancreatic cancer].
Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Catheters, Indwelling; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intra-Arterial; Leucovorin; Methotrexate; Pancreatic Neoplasms; Radiotherapy, High-Energy; Retrospective Studies; Survival Rate | 1992 |
[Effective treatment of liver metastasis and peritoneal dissemination of gastric cancer using intra-arterial therapy--a case report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Norepinephrine; Peritoneal Neoplasms; Stomach Neoplasms | 1992 |
Novel mechanism(s) of resistance to 5-fluorouracil in human colon cancer (HCT-8) sublines following exposure to two different clinically relevant dose schedules.
Topics: Cell Line; Cell Survival; Colonic Neoplasms; Drug Resistance; Floxuridine; Fluorouracil; Humans; Kinetics; Methotrexate; Pteroylpolyglutamic Acids; Pyrimidines; RNA, Neoplasm; Thymidylate Synthase; Time Factors | 1992 |
Etoposide, doxorubicin, and cisplatin chemotherapy for advanced gastric cancer: an old lesson revisited.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Etoposide; Fluorouracil; Humans; Methotrexate; Stomach Neoplasms; Survival Analysis | 1992 |
[Flow cytometric analysis of effects of chemohormonal agents on the cell cycle distribution of MCF-7 cells].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Cycle; Doxorubicin; Female; Flow Cytometry; Fluorouracil; Humans; Methotrexate; Tamoxifen; Tumor Cells, Cultured | 1992 |
Differential effects of drugs upon hematopoiesis can be assessed in long-term bone marrow cultures established on nylon screens.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Fluorouracil; Hematopoiesis; Male; Methotrexate; Nylons; Rats | 1992 |
Detection of contamination with antineoplastic agents in a hospital pharmacy department.
Topics: Air; Antineoplastic Agents; Cyclophosphamide; Environmental Monitoring; Fluorouracil; Humans; Methotrexate; Pharmacy Service, Hospital | 1992 |
Endocrine profile in breast cancer patients receiving chemotherapy.
Topics: Adult; Age Factors; Amenorrhea; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Estradiol; Estrone; Female; Fluorouracil; Hormones; Humans; Luteinizing Hormone; Methotrexate; Middle Aged; Obesity; Prolactin | 1992 |
Expression of collateral sensitivity to cisplatin, methotrexate, and fluorouracil in a human ovarian carcinoma cell line following exposure to fractionated x-irradiation in vitro.
Topics: Cisplatin; Combined Modality Therapy; Cystadenocarcinoma; Drug Resistance; Female; Fluorouracil; Glutathione; Humans; Methotrexate; Ovarian Neoplasms; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Tumor Cells, Cultured | 1992 |
Enhanced 5-fluorouracil cytotoxicity and elevated 5-fluoronucleotides in the rat Walker carcinosarcoma following methotrexate pre-treatment: a 19F-MRS study in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma 256, Walker; Cell Division; Drug Administration Schedule; Female; Fluorouracil; Injections, Intraperitoneal; Injections, Intravenous; Magnetic Resonance Spectroscopy; Methotrexate; Rats; Rats, Inbred Strains; Time Factors | 1992 |
[Sequential methotrexate and 5-fluorouracil, doxorubicin, and cisplatin for advanced urothelial cancer].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Kidney Neoplasms; Male; Methotrexate; Middle Aged; Ureteral Neoplasms; Urinary Bladder Neoplasms | 1992 |
Sequential methotrexate and fluorouracil in colon cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Leucovorin; Methotrexate | 1992 |
Akinetic mutism in bilateral necrotizing leucoencephalopathy after radiation and chemotherapy: electrophysiological and autopsy findings.
Topics: Adult; Afferent Pathways; Akinetic Mutism; Alpha Rhythm; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cranial Fossa, Posterior; Cranial Irradiation; Cyclophosphamide; Demyelinating Diseases; Doxorubicin; Electroencephalography; Evoked Potentials, Somatosensory; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Necrosis; Stereotyped Behavior | 1992 |
Toxicity and side-effects of combination chemohormonal therapy of advanced breast cancer.
Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Nausea; Ovariectomy; Prednisone; Tamoxifen; Thrombophlebitis; Vomiting | 1992 |
[Chemotherapy and thymostimulin in the treatment of advanced-stage breast neoplasms].
Topics: Adjuvants, Immunologic; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Immunoglobulins; Lymphatic Metastasis; Lymphocyte Activation; Lymphocyte Subsets; Methotrexate; Middle Aged; Neoplasm Metastasis; Thymus Extracts | 1992 |
Dose intensity of chemotherapy with cyclophosphamide, methotrexate and 5-fluorouracil in the elderly with advanced breast cancer.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Creatinine; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Hematologic Diseases; Humans; Methotrexate | 1992 |
Characterization of a cisplatin-resistant human ovarian carcinoma cell line expressing cross-resistance to 5-fluorouracil but collateral sensitivity to methotrexate.
Topics: Antineoplastic Agents; Catalase; Cell Division; Cell Line; Cell Survival; Cisplatin; DNA-Directed DNA Polymerase; Drug Resistance; Female; Fluorouracil; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Humans; Methotrexate; NAD(P)H Dehydrogenase (Quinone); Ovarian Neoplasms; Superoxide Dismutase; X-Rays | 1992 |
Azidothymidine and dipyridamole as biochemical response modifiers: synergism with methotrexate and 5-fluorouracil in human colon and pancreatic carcinoma cells.
Topics: Adenocarcinoma; Cell Division; Cell Line; Cell Survival; Colonic Neoplasms; Dipyridamole; DNA Replication; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; Humans; Methotrexate; Pancreatic Neoplasms; Thymidine; Tumor Stem Cell Assay; Zidovudine | 1992 |
[Chemotherapy of advanced breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Survival Rate; Treatment Outcome | 1992 |
Intravenous or oral adjuvant CMF for node-positive breast cancer.
Topics: Adjuvants, Pharmaceutic; Administration, Oral; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Infusions, Intravenous; Leukopenia; Lymph Node Excision; Lymphatic Metastasis; Mastectomy, Simple; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; New South Wales; Prognosis; Survival Analysis; Survival Rate | 1992 |
[Mechanism of synergism and clinical results of sequential methotrexate and 5-fluorouracil in the treatment of gastric cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Chemotherapy, Adjuvant; Drug Administration Schedule; Drug Synergism; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Stomach Neoplasms; Survival Rate; Time Factors; Tumor Cells, Cultured | 1992 |
MMAF for advanced gastric cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Fluorouracil; Humans; Methotrexate; Mitomycin; Stomach Neoplasms | 1992 |
Effect of etoposide, carmustine, vincristine, 5-fluorouracil, or methotrexate on radiobiologically oxic and hypoxic cells in a C3H mouse mammary carcinoma in situ.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma in Situ; Carmustine; Cell Division; Cell Hypoxia; Combined Modality Therapy; Etoposide; Female; Fluorouracil; Male; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mice, Inbred C3H; Vincristine | 1992 |
Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency. A potentially more common pharmacogenetic syndrome.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Combined Modality Therapy; Cyclophosphamide; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Humans; Leukocyte Count; Male; Methotrexate; Monocytes; Oxidoreductases; Pedigree; Receptors, Progesterone | 1991 |
Lack of correlation between histologic findings and response to chemotherapy in metastatic breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Retrospective Studies; Survival Analysis; Tamoxifen | 1991 |
[Platelet aggregation during adjuvant chemotherapy with CMF].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Papillary; Cyclophosphamide; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Platelet Aggregation | 1991 |
Comparison of long-term survival of 1986 consecutive patients with breast cancer treated at the National Cancer Institute of Milano, Italy (1971 to 1972 and 1977 to 1978).
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Italy; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Survival Rate | 1991 |
[Possibilities of the cytological method in the determination of therapeutic pathomorphosis of breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Combined Modality Therapy; Cyclophosphamide; Cytodiagnosis; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Mastectomy, Radical; Methotrexate; Radiotherapy Dosage | 1991 |
Chemotherapy for pancreatic carcinoma.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Fluorouracil; Humans; Methotrexate; Pancreatic Neoplasms; Survival Rate | 1991 |
A human leukemia cell line made resistant to two folate analogues, trimetrexate and N10-propargyl-5,8-dideazafolic acid (CB3717).
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cell Line; Cisplatin; Cross Reactions; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Etoposide; Fluorouracil; Folic Acid; Humans; Leucovorin; Membrane Glycoproteins; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinazolines; RNA, Messenger; Thymidylate Synthase; Trimetrexate; Vincristine | 1991 |
Induction chemotherapy with cisplatin, fluorouracil, and high-dose leucovorin for locally advanced head and neck cancer: a clinical and pharmacologic analysis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Remission Induction; Stereoisomerism | 1990 |
Mediastinal large-B-cell lymphoma with sclerosis: a clinical study of 21 patients.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Lymphoma, Non-Hodgkin; Male; Mediastinal Neoplasms; Methotrexate; Neoplasm Staging; Prednisone; Remission Induction; Sclerosis; Sex Factors; Survival Rate; Vincristine | 1990 |
Predictive value of serum alkaline DNase activity variations in treatment of head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Cisplatin; Combined Modality Therapy; Deoxyribonuclease I; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Predictive Value of Tests | 1990 |
[Comparative evaluation of radiotherapy and chemoradiotherapy in inoperable cancer of the esophagus].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Doxorubicin; Esophageal Neoplasms; Evaluation Studies as Topic; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Time Factors | 1990 |
[Initial results of combined surgical-medical therapy for metastatic cancer of the stomach].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fluorouracil; Gastrectomy; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Palliative Care; Reoperation; Stomach Neoplasms | 1990 |
[Neoadjuvant chemotherapy of head and neck cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Random Allocation | 1991 |
[Antineoplastic chemotherapy in digestive tumors].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Doxorubicin; Fluorouracil; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Interleukin-2; Leucovorin; Methotrexate; Mitomycin; Recombinant Proteins; Stomach Neoplasms | 1991 |
Loss of murine tumor thymidine kinase activity in vivo following 5-fluorouracil (FUra) treatment by incorporation of FUra into RNA.
Topics: Animals; DNA; Dose-Response Relationship, Drug; Fluorouracil; Mammary Neoplasms, Experimental; Methotrexate; Mice; Ornithine Decarboxylase; RNA; Thymidine Kinase; Thymidylate Synthase; Tritium; Uridine | 1991 |
Combined chemotherapy with bleomycin, adriamycin, and platinum in advanced thyroid cancer.
Topics: Adenocarcinoma; Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Betamethasone; Bleomycin; Carcinoma; Carmustine; Cisplatin; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Metoclopramide; Middle Aged; Nausea; Thyroid Neoplasms; Vincristine | 1991 |
Alteration of the inner surface of venous catheters by antineoplastic drugs.
Topics: Antineoplastic Agents; Bleomycin; Carmustine; Catheterization, Peripheral; Cisplatin; Contrast Media; Doxorubicin; Equipment Design; Fluorouracil; Ifosfamide; Materials Testing; Methotrexate; Microscopy, Electron; Polyurethanes; Rheology; Silicones; Stress, Mechanical; Surface Properties; Tensile Strength; Time Factors; Vincristine | 1991 |
Response of brain metastases from breast cancer to systemic chemotherapy.
Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Survival Analysis; Tomography, X-Ray Computed | 1992 |
[European School of Oncology (ESO)--gastric cancer treatment strategy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Fluorouracil; Humans; Methotrexate; Prognosis; Stomach Neoplasms | 1992 |
Preoperative chemotherapy in primarily inoperable cancer of the breast.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Survival Rate; Tamoxifen; Vincristine | 1991 |
Ifosfamide, methotrexate and 5-fluorouracil for pretreated advanced breast cancer.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Fluorouracil; Hematopoiesis; Humans; Ifosfamide; Liver Neoplasms; Mesna; Methotrexate; Middle Aged; Risk Factors; Survival Analysis | 1991 |
Two simple indexes used to evaluate the impact of therapy on the quality of life of patients receiving primary chemotherapy for operable breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Discriminant Analysis; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Mitoxantrone; Quality of Life; Reproducibility of Results; Surveys and Questionnaires | 1991 |
Carboplatin, continuous infusion fluorouracil and mid-cycle high-dose methotrexate as initial treatment in patients with locally advanced head and neck cancer. Hellenic Co-operative Oncology Group Study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Radiography; Radiotherapy Dosage; Remission Induction; Survival Analysis | 1991 |
Studies on the changes in plasma lipids and lipoproteins in CMF treated breast cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Body Weight; Breast Neoplasms; Cholesterol; Cisplatin; Fatty Acids; Female; Fluorouracil; Humans; Lipids; Lipoproteins; Menopause; Methotrexate; Phospholipids; Triglycerides | 1991 |
Choroidal metastases as a presenting sign after 24 years of a primary breast cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Choroid Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged | 1991 |
[Use of thymoptin and chemotherapy in the complex treatment of breast cancer].
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Neutrophils; Peptides; Phagocytosis; T-Lymphocytes; Thymosin; Thymus Extracts; Vincristine | 1991 |
Surgical adjuvant chemotherapy for breast cancer: a comparison of CMF and CAF regimens.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate | 1991 |
MMAF for advanced gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mitomycins; Prognosis; Stomach Neoplasms | 1991 |
Schedule-dependent in vitro combination effects of methotrexate and 5-fluorouracil in human tumor cell lines.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Survival; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Microcomputers; Molecular Conformation; Neoplasms; Software; Time Factors; Tumor Cells, Cultured | 1991 |
The interrelationship between the anti-mitotic action of the somatostatin analog octreotide and that of cytostatic drugs and suramin.
Topics: Animals; Antineoplastic Agents; Cell Line; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Interactions; Fluorouracil; Kinetics; Methotrexate; Mitosis; Octreotide; Pituitary Neoplasms; Prolactin; Rats; Suramin; Vincristine | 1991 |
Effect of solcoseryl on antitumour action and acute toxicity of some antineoplastic drugs.
Topics: Actihaemyl; Animals; Antineoplastic Agents; Cytarabine; Drug Interactions; Fluorouracil; Injections, Intraperitoneal; Injections, Intravenous; Lethal Dose 50; Leukemia P388; Male; Methotrexate; Mice; Mice, Inbred DBA; Mitoxantrone | 1991 |
[Therapeutic results and toxic side effects of the cytostasan, adriamycin and vincristine combination as second line therapy in metastatic breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis | 1991 |
Hematopoiesis on suspended nylon screen-stromal cell microenvironments.
Topics: Animals; Antibodies, Monoclonal; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Clone Cells; Colony-Forming Units Assay; Cyclophosphamide; Cytarabine; Cytotoxicity Tests, Immunologic; Dose-Response Relationship, Drug; Flow Cytometry; Fluorouracil; Killer Cells, Natural; Male; Methotrexate; Phenotype; Rats | 1991 |
The F-MACHOP regimen in advanced diffuse aggressive lymphomas: summary of ten years' experience at a single institution.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Fluorouracil; Humans; Leucovorin; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine | 1991 |
Clinical and pathological restaging in aggressive non-Hodgkin's lymphomas.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Fluorouracil; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Prednisone; Prospective Studies; Vincristine | 1991 |
Adjuvant therapy of stage II breast cancer treated with CMFVP, radiation therapy and VATH following lumpectomy. A pilot trial.
Topics: Adjuvants, Pharmaceutic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Esthetics; Female; Fluorouracil; Fluoxymesterone; Hematologic Diseases; Humans; Lymphatic Metastasis; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Pilot Projects; Prednisone; Radiotherapy; Survival Rate; Thiotepa; Vinblastine; Vincristine | 1991 |
[Hepatic arterial infusion chemotherapy and loco-regional treatment and irradiation of pancreas tumor in non-resectable pancreas cancer with liver metastases].
Topics: Administration, Oral; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Leucovorin; Liver Neoplasms; Methotrexate; Pancreatic Neoplasms; Radiotherapy, High-Energy | 1991 |
[Arterial infusion chemotherapy combined with biochemical modulation in cancer patients].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Fluorouracil; Humans; Immunologic Factors; Infusions, Intra-Arterial; Interferon Type I; Leucovorin; Methotrexate; Mitomycin; Mitomycins; Neoplasms | 1991 |
Protective effects of swainsonine on murine survival and bone marrow proliferation during cytotoxic chemotherapy.
Topics: Alkaloids; Analysis of Variance; Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cell Division; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Mannosidases; Methotrexate; Mice; Mice, Inbred C57BL; Survival Rate; Swainsonine | 1991 |
Adjuvant systemic therapy for operable breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Prognosis; Receptors, Estrogen; Tamoxifen | 1991 |
In vivo measurements of intratumoral metabolism, modulation, and pharmacokinetics of 5-fluorouracil, using 19F nuclear magnetic resonance spectroscopy.
Topics: Animals; Carcinoma 256, Walker; Fluorine; Fluorouracil; Kinetics; Least-Squares Analysis; Magnetic Resonance Spectroscopy; Male; Methotrexate; Models, Biological; Rats; Rats, Inbred Strains | 1991 |
Increased growth adaptability to 5-fluorouracil and methotrexate of HT-29 sub-populations selected for their commitment to differentiation.
Topics: Cell Differentiation; Cell Division; Colonic Neoplasms; Drug Resistance; Fluorescent Antibody Technique; Fluorouracil; Humans; Methotrexate; Tumor Cells, Cultured | 1991 |
Chemotherapy in advanced gastric carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Fluorouracil; Humans; Methotrexate; Mitomycin; Multivariate Analysis; Stomach Neoplasms | 1991 |
[Adjuvant chemotherapy in premenopausal women].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Recurrence, Local; Prognosis; Quality of Life | 1991 |
Modulation of fluorouracil by methotrexate.
Topics: Drug Synergism; Fluorouracil; Humans; Leucovorin; Methotrexate | 1991 |
Adjuvant oophorectomy versus CMF for premenopausal, node-positive, hormone receptor positive patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Menopause; Methotrexate; Ovariectomy | 1991 |
[Chemotherapeutic pathomorphosis of breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Cisplatin; Female; Fluorouracil; Humans; Lymph Node Excision; Mastectomy, Radical; Methotrexate; Mitosis; Necrosis; Polymorphism, Genetic | 1990 |
[Results of treatment following breast-saving therapy: analysis of intramammary recurrence].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Multiple Primary; Survival Rate | 1990 |
Response to doxorubicin/methotrexate/fluorouracil in advanced adenocarcinoma of pancreas or biliary tract.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Pancreatic Neoplasms; Prognosis | 1990 |
Doxorubicin/methotrexate/fluorouracil in advanced pancreatic cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Fluorouracil; Humans; Methotrexate; Pancreatic Neoplasms | 1990 |
Barrett esophagus after chemotherapy with cyclophosphamide, methotrexate, and 5-fluorouracil (CMF): an iatrogenic injury?
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Barrett Esophagus; Biopsy; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Esophagoscopy; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prospective Studies | 1991 |
Role of folylpolyglutamates in biochemical modulation of fluoropyrimidines by leucovorin.
Topics: Cell Division; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Fluorouracil; Humans; Leucovorin; Methotrexate; Pteroylpolyglutamic Acids; T-Lymphocytes; Thymidylate Synthase; Tumor Cells, Cultured | 1991 |
Predictors of physician nonadherence to chemotherapy regimens.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Attitude of Health Personnel; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Patient Compliance; Practice Patterns, Physicians'; Prednisone; Socioeconomic Factors; Vincristine | 1991 |
Radiation induction of drug resistance in RIF-1: correlation of tumor and cell culture results.
Topics: Animals; Dose-Response Relationship, Radiation; Doxorubicin; Drug Resistance; Etoposide; Fluorouracil; Methotrexate; Mice; Tumor Cells, Cultured | 1991 |
Selective uptake of toxic nucleoside (125IUdR) by resistant cancer.
Topics: Adenocarcinoma; Animals; Cell Line; Choriocarcinoma; Colon; Colonic Neoplasms; Cytarabine; Drug Resistance; Female; Fluorouracil; Humans; Hydroxyurea; Idoxuridine; Iodine Radioisotopes; Male; Methotrexate; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Uterine Neoplasms | 1991 |
Fluoropyrimidine biochemical modulation in colon cancer: pharmacology relevant in both the laboratory and the clinic.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Humans; Leucovorin; Methotrexate | 1991 |
Weight gain with breast cancer adjuvant treatment.
Topics: Adaptation, Psychological; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Melphalan; Methotrexate; Middle Aged; Prednisone; Recurrence; Regression Analysis; Social Support; Vinblastine; Weight Gain | 1991 |
Cancer chemotherapy: hormonal changes and recurring asthma.
Topics: Adenocarcinoma; Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Asthma; Breast Neoplasms; Cyclophosphamide; Drug Hypersensitivity; Female; Fluorouracil; Humans; Methotrexate; Recurrence | 1991 |
The CMF-regimen. Toxicity patterns following stepwise combinations of cyclophosphamide, methotrexate and fluorouracil.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Methotrexate; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1991 |
Second-line chemotherapy of advanced colorectal cancer with sequential high-dose methotrexate and 5-fluorouracil.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local | 1991 |
Effects of cytotoxic chemotherapy on ovarian and adrenal steroidogenesis in pre-menopausal breast cancer patients.
Topics: Acetone; Adrenal Glands; Adult; Aged; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Cisplatin; Estradiol; Female; Fluorouracil; Gonadotropins; Humans; Menstruation; Methotrexate; Middle Aged; Ovary; Pyrones | 1991 |
AZT: a biochemical response modifier of methotrexate and 5-fluorouracil cytotoxicity in human ovarian and pancreatic carcinoma cells.
Topics: Animals; Binding, Competitive; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Female; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Methotrexate; Ovarian Neoplasms; Pancreatic Neoplasms; Rats; Thymidine; Thymidine Kinase; Tumor Cells, Cultured; Zidovudine | 1991 |
What is the value of methotrexate in the treatment of advanced colorectal cancer?
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colorectal Neoplasms; Fluorouracil; Humans; Leucovorin; Methotrexate; Prognosis | 1991 |
In vivo monitoring of changes in 5-fluorouracil metabolism induced by methotrexate measured by 19F NMR spectroscopy.
Topics: Animals; Female; Fluorouracil; Magnetic Resonance Spectroscopy; Male; Mammary Neoplasms, Experimental; Methotrexate; Mice; Premedication | 1991 |
Cosmetic results after surgery, chemotherapy, and radiation therapy for early breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Esthetics; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Prednisone; Retrospective Studies; Vincristine | 1991 |
Comparative effect of 6S, 6R and 6RS leucovorin on methotrexate rescue and on modulation of 5-fluorouracil.
Topics: Analysis of Variance; Cell Line; Cell Survival; Deoxyuridine; DNA Replication; Fluorouracil; Humans; Leucovorin; Methotrexate; Stereoisomerism; Tumor Stem Cell Assay | 1991 |
Preoperative multimodal therapy for locally advanced non-inflammatory breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cobalt Radioisotopes; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy, Radical; Mastectomy, Simple; Menopause; Methotrexate; Preoperative Care; Survival Rate | 1991 |
Efficacy of sequential methotrexate, fluorouracil, and leucovorin rescue: due to the 24-hour interval? The leucovorin-fluorouracil combination? Both?
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; Humans; Leucovorin; Methotrexate | 1991 |
[Colorectal carcinogenesis, tumor progression and chemoresistance].
Topics: Camptothecin; Cell Transformation, Neoplastic; Colorectal Neoplasms; Drug Resistance; Fluorouracil; Growth Inhibitors; Humans; Methotrexate; Tumor Cells, Cultured | 1990 |
Treatment of metastatic gastric carcinoma with a modified FAMTX chemotherapy regimen.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prospective Studies; Stomach Neoplasms; Survival Rate | 1990 |
Fist line chemotherapy in advanced ovarian cancer: a comparison of three therapeutic regimes.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Survival Rate | 1990 |
Polyamine excretion from human cancer cells.
Topics: Cell Division; Fluorouracil; Humans; Methotrexate; Mitoguazone; Polyamines; Tumor Cells, Cultured | 1990 |
Induction of macrophage procoagulant expression by cisplatin, daunorubicin and doxorubicin.
Topics: Animals; Antibiotics, Antineoplastic; Blood Coagulation Factors; Cisplatin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Fluorouracil; Gene Expression Regulation; Interferon-gamma; Lipopolysaccharides; Macrophages; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL | 1990 |
Cyclophosphamide, methotrexate, and 5-fluorouracil (CMF)-induced ocular toxicity.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Conjunctivitis; Cromolyn Sodium; Drug Administration Schedule; Eye; Fluorouracil; Humans; Methotrexate; Ophthalmic Solutions; Tears | 1990 |
[Hemosorption and polychemotherapy with hyperglycemia in the treatment of ovarian cancer].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Glucose; Carcinoma; Combined Modality Therapy; Evaluation Studies as Topic; Female; Fluorouracil; Glucose; Hemoperfusion; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms; Thiotepa | 1990 |
Toxic response to topical fluorouracil in two rheumatoid arthritis patients receiving low-dose, weekly methotrexate.
Topics: Aged; Arthritis, Rheumatoid; Drug Eruptions; Drug Synergism; Fluorouracil; Humans; Keratosis; Male; Methotrexate; Middle Aged; Ointments; Time Factors | 1990 |
An EORTC phase II study of sequential methotrexate-fluorouracil in locally advanced or metastatic gastric cancer. The EORTC Gastrointestinal Cancer Cooperative Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Stomach Neoplasms | 1990 |
Modification of 5-fluorouracil activity by high-dose methotrexate or leucovorin in advanced colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Colorectal Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Prognosis | 1990 |
Modulation of fluoropyrimidines by pretreatment with antifolates or folinic acid (leucovorin).
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Floxuridine; Fluorouracil; Humans; Leucovorin; Methotrexate; Neoplasms | 1990 |
Effect of preoperative chemotherapy on mastectomy for locally advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Estrogens, Conjugated (USP); Female; Fluorouracil; Hospitalization; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Necrosis; Postoperative Complications; Retrospective Studies; Skin; Surgical Flaps; Tamoxifen; Time Factors | 1990 |
Long-term complete remission of stage IV breast cancer after high-dose chemotherapy and autologous bone marrow transplantation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Female; Fluorouracil; Humans; Lung Neoplasms; Mastectomy, Modified Radical; Mediastinal Neoplasms; Methotrexate; Neoplasm Staging; Remission Induction | 1990 |
5-Fluorouracil cardiotoxicity.
Topics: Angina Pectoris; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cisplatin; Electrocardiography; Female; Fluorouracil; Humans; Methotrexate; Middle Aged | 1990 |
Toxicities of trichosanthin and alpha-momorcharin, abortifacient proteins from Chinese medicinal plants, on cultured tumor cell lines.
Topics: Abortifacient Agents, Nonsteroidal; Animals; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Cell Division; Cell Line; Choriocarcinoma; Chorionic Gonadotropin; Cisplatin; Drugs, Chinese Herbal; Fluorouracil; Humans; Liver Neoplasms; Melanoma; Methotrexate; Plant Proteins; Progesterone; Ribosomal Proteins; Ribosome Inactivating Proteins; Trichosanthin; Tumor Cells, Cultured | 1990 |
Rapid chemosensitivity assay with human normal and tumor cells in vitro.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Survival; Cells, Cultured; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Fibroblasts; Fluorouracil; Humans; Keratinocytes; Liver Neoplasms; Melanocytes; Melanoma; Methotrexate; Neutral Red; Time Factors; Tumor Cells, Cultured | 1990 |
Bioavailability of cyclophosphamide in the CMF regimen.
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Infusions, Intravenous; Methotrexate; Middle Aged | 1990 |
Breast cancer staging and the "alert": an educational dilemma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Communication; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Prednisone; Publishing; Tamoxifen | 1990 |
Therapeutic strategies in inflammatory breast carcinoma based on prognostic factors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; France; Humans; Life Tables; Methotrexate; Mitomycin; Mitomycins; Multivariate Analysis; Radiotherapy Dosage; Remission Induction; Survival Rate; Tamoxifen; Vinblastine; Vincristine | 1990 |
Drug resistance following irradiation of RIF-1 tumors: influence of the interval between irradiation and drug treatment.
Topics: Animals; Antineoplastic Agents; Cell Line; Combined Modality Therapy; Dose-Response Relationship, Radiation; Doxorubicin; Drug Resistance; Fluorouracil; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Time Factors | 1990 |
Histopathological changes following anterior chemotherapy in advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Prospective Studies | 1990 |
Preoperative chemotherapy is beneficial for geriatric patients with locally advanced and metastatic breast cancer.
Topics: Adenocarcinoma; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Premedication; Prognosis; Retrospective Studies | 1990 |
Chemotherapy of breast cancer in Nigerians: side-effects and quality of life.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Quality of Life | 1990 |
[Antineoplastic activity of combinations of cytostatics and dextran-ferrite administered to mice with leukemia P-388].
Topics: Animals; Antineoplastic Agents; Cisplatin; Cyclophosphamide; Dactinomycin; Daunorubicin; Doxorubicin; Drug Combinations; Fluorouracil; Iron-Dextran Complex; Leukemia P388; Melphalan; Methotrexate; Mice; Tegafur | 1990 |
Interaction of Candida albicans with murine gastrointestinal mucosa from methotrexate and 5-fluorouracil treated animals: in vitro adhesion and prevention.
Topics: Animals; Candida albicans; Cell Adhesion; Chitin; Female; Fluorouracil; Gastric Mucosa; Intestinal Mucosa; Leukocyte Count; Methotrexate; Mice; Mice, Inbred ICR; Organ Size; Spleen | 1990 |
Higher average received relative dose intensities of cyclophosphamide, methotrexate and 5-fluorouracil using a 24-hour method: implications for improved cure rates in breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Prednisone; Remission Induction; Thrombocytopenia; Vincristine | 1990 |
[Consensus and controversy in adjuvant treatment indications in breast cancers].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Tamoxifen | 1990 |
[Study of procreation capacity of men after treatment of their malignant tumors (melanoblastoma, thyroid carcinoma) with ionizing radiation and cytostatic agents].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cobalt Radioisotopes; Cyclophosphamide; Dacarbazine; Fertility; Fluorouracil; Humans; Male; Melanoma; Methotrexate; Radiotherapy Dosage; Sperm Count; Sperm Motility; Spermatozoa; Thyroid Neoplasms | 1990 |
Dose-intense weekly cyclophosphamide, methotrexate, 5-fluorouracil, vincristine and prednisolone (CMFP) in advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Prospective Studies | 1990 |
Bone mineral density after adjuvant chemotherapy for premenopausal breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Density; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Osteoporosis; Risk Factors | 1990 |
Sixteen-week dose-intense chemotherapy in the adjuvant treatment of breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Methotrexate; Middle Aged; Pilot Projects; Vincristine | 1990 |
Tumor necrosis factor and cytotoxic agents. Effect on squamous carcinoma lines.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Survival; Cisplatin; Colorimetry; Dactinomycin; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Humans; In Vitro Techniques; Methotrexate; Recombinant Proteins; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
A new chemotherapeutic regimen in the treatment of advanced gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Stomach Neoplasms; Survival Rate | 1990 |
Sequential high-dose methotrexate, 5-fluorouracil, and doxorubicin for treatment of advanced pancreatic cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms | 1990 |
Acute non lymphoid leukemia following CMF treatment as adjuvant therapy in positive node breast cancer. Case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Female; Fluorouracil; Humans; Leukemia, Myeloid, Acute; Lymphatic Metastasis; Methotrexate | 1990 |
Flow cytometric analysis of human breast tumors and assessment of in vitro chemosensitivity by clonogenic assays.
Topics: Breast Neoplasms; Chromosomes; Doxorubicin; Extracellular Matrix; Female; Flow Cytometry; Fluorouracil; Humans; Methotrexate; Neoplastic Stem Cells; Ploidies; Receptors, Estrogen; Receptors, Progesterone; Tumor Stem Cell Assay | 1990 |
Biological monitoring screening of patients provided antineoplastic drugs including adriamycin, cyclophosphamide, 5-fluorouracil, methotrexate, and vincristine.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Creatinine; Cyclophosphamide; Doxorubicin; Electrolytes; Female; Fluorouracil; Glucaric Acid; Humans; Male; Methotrexate; Middle Aged; Monitoring, Physiologic; Mutagenicity Tests; Sugar Acids; Sulfides; Vincristine | 1990 |
The CMF-regimen. Modulation of cyclophosphamide uptake and clearance by methotrexate and fluorouracil.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Fluorouracil; Metabolic Clearance Rate; Methotrexate; Rats; Rats, Inbred Strains; Time Factors | 1990 |
High risk of therapy-related leukemia and preleukemia after therapy with prednimustine, methotrexate, 5-fluorouracil, mitoxantrone, and tamoxifen for advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Female; Fluorouracil; Humans; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Mitoxantrone; Prednimustine; Preleukemia; Risk Factors; Survival Rate; Tamoxifen | 1990 |
[Adjuvant chemotherapy of breast cancer with the CMFV protocol].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Survival Rate; Vincristine | 1990 |
[Chemotherapy of disseminated forms of breast cancer using platinum derivatives].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Phosphoramide Mustards; Time Factors | 1990 |
Ifosfamide, methotrexate, and 5-fluorouracil: effective combination in resistant breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Resistance; Female; Fluorouracil; Humans; Ifosfamide; Methotrexate; Middle Aged | 1990 |
Adjuvant methotrexate-5-fluorouracil for extracapsular squamous cell carcinoma in cervical metastasis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate | 1990 |
[Sequential methotrexate.5FU chemotherapy for gastric cancer--comparison between intra-aortic infusion therapy and intravenous administration therapy].
Topics: Adult; Aged; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 1990 |
Effects of adjuvant chemotherapy on specific and non-specific immune mechanisms.
Topics: Antibody Formation; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Immune Tolerance; Killer Cells, Natural; Lymphocyte Activation; Methotrexate; Receptors, Interleukin-2; T-Lymphocytes | 1990 |
Cardiovascular autonomic function in anthracycline-treated breast cancer patients.
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Autonomic Nervous System; Blood Pressure; Breast Neoplasms; Cardiovascular System; Cisplatin; Drug Evaluation; Electrocardiography; Female; Fluorouracil; Humans; Methotrexate; Respiration; Stroke Volume; Valsalva Maneuver | 1990 |
Barrett's esophagus after antineoplastic chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Barrett Esophagus; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged | 1990 |
[The role of radiotherapy in the multimodal treatment of locally advanced breast carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Diethylstilbestrol; Doxorubicin; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Neoplasm Staging | 1990 |
The Duke AFM Program. Intensive induction chemotherapy for metastatic breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Middle Aged; Mucous Membrane; Remission Induction | 1990 |
Protective effects of tumor necrosis factor on murine hematopoiesis during cycle-specific cytotoxic chemotherapy.
Topics: Animals; Bone Marrow; Colony-Forming Units Assay; Cyclophosphamide; Erythrocyte Count; Fluorouracil; Hematopoiesis; Hematopoietic Stem Cells; Leukocyte Count; Methotrexate; Mice; Mice, Inbred BALB C; Neutrophils; Platelet Count; Recombinant Proteins; Tumor Necrosis Factor-alpha; Vinblastine | 1990 |
Modulating fluorouracil with different drugs: the Padua experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Drug Synergism; Fluorouracil; Humans; Injections, Intraperitoneal; Injections, Intravenous; Interferon Type I; Leucovorin; Methotrexate | 1990 |
[Biliary and pancreatic excretion of methotrexate (MTX) and 5-FU on the MTX/5-FU sequential therapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bile; Common Bile Duct Neoplasms; Drug Administration Schedule; Duodenal Neoplasms; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Pancreatic Juice | 1990 |
Azidothymidine inhibition of thymidine kinase and synergistic cytotoxicity with methotrexate and 5-fluorouracil in rat hepatoma and human colon cancer cells.
Topics: Animals; Cell Line; Cell Survival; Colonic Neoplasms; Drug Synergism; Fluorouracil; Humans; Kinetics; Liver Neoplasms, Experimental; Methotrexate; Rats; Thymidine; Thymidine Kinase; Tumor Cells, Cultured; Zidovudine | 1990 |
[Assessment of individual sensitivity to chemotherapy of human pulmonary tumors transplanted to subrenal capsule of CBA mice].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Methylnitrosourea; Mice; Mice, Inbred CBA; Prospidium; Subrenal Capsule Assay; Vincristine | 1990 |
Natural killer activity in patients with breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Cytotoxicity, Immunologic; Female; Flow Cytometry; Fluorouracil; Humans; Killer Cells, Natural; Methotrexate; Middle Aged; Tamoxifen | 1990 |
Need for new adjuvant chemotherapy schedules in breast carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate | 1990 |
Phase II trial of sequential methotrexate and 5-fluorouracil with leucovorin in children with sarcomas.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Evaluation; Drug Synergism; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Male; Methotrexate; Rhabdomyosarcoma; Sarcoma, Ewing | 1990 |
Adjuvant chemotherapy and scar irradiation in breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Prednisone; Prospective Studies; Recurrence; Survival Rate | 1990 |
Intraarterial induction chemotherapy in locally advanced stage III breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Injections, Intramuscular; Leucovorin; Mastectomy, Modified Radical; Methotrexate; Neoplasm Staging; Remission Induction; Survival Rate; Vincristine | 1990 |
[Drug therapy of pulmonary metastases of breast cancer].
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Vincristine | 1990 |
[The treatment of refractory choriocarcinoma].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Pregnancy; Prognosis; Uterine Neoplasms; Vincristine | 1990 |
Contributions of drug solubilization, partitioning, barrier disruption, and solvent permeation to the enhancement of skin permeation of various compounds with fatty acids and amines.
Topics: Adjuvants, Pharmaceutic; Adult; Amines; Benzoates; Benzoic Acid; Diffusion; Fatty Acids; Female; Fluorouracil; Humans; In Vitro Techniques; Indomethacin; Male; Membranes, Artificial; Methotrexate; Middle Aged; Propylene Glycol; Propylene Glycols; Skin Absorption; Solubility; Solvents; Testosterone | 1990 |
Introduction to 5-fluorouracil modulation.
Topics: Antimetabolites, Antineoplastic; Aspartic Acid; Drug Interactions; Fluorouracil; Humans; Leucovorin; Methotrexate; Phosphonoacetic Acid; Uridine | 1990 |
Phase I trial of PALA, methotrexate, fluorouracil, leucovorin, and uridine rescue in patients with advanced cancer. The use of uridine to decrease fluorouracil toxicity.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Drug Evaluation; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasms; Phosphonoacetic Acid; Uridine | 1990 |
Primary chemotherapy to avoid mastectomy in tumors with diameters of three centimeters or more.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Menopause; Methotrexate; Recurrence | 1990 |
Alternating combination chemotherapy using cisplatin-bleomycin with sequential methotrexate-5-FU plus leucovorin rescue in patients with head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Time Factors | 1985 |
Multicentric reticulohistiocytosis and cancer: a case report and review of the literature.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arthritis; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cyclophosphamide; Female; Fluorouracil; Histiocytes; Humans; Lymphatic Diseases; Lymphatic Metastasis; Methotrexate; Middle Aged; Paraneoplastic Syndromes; Prednisone; Recurrence; Skin Diseases; Staining and Labeling | 1985 |
[Chemoradiation treatment of pancreatic cancer].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Palliative Care; Pancreatic Neoplasms; Radiotherapy Dosage; Time Factors; Vincristine | 1985 |
[Sequential combination chemotherapy consisting of vincristine, peplomycin, methotrexate, cis-diamminedichloroplatinum (II), cytosine arabinoside and 5-fluorouracil, for advanced urothelial cancer].
Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Cytarabine; Female; Fluorouracil; Humans; Kidney Neoplasms; Male; Methotrexate; Mice; Mice, Nude; Middle Aged; Neoplasm Transplantation; Peplomycin; Ureteral Neoplasms; Urinary Bladder Neoplasms; Vincristine | 1985 |
Multimodality therapy for unresectable squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mouth Diseases; Neck Dissection; Radiotherapy; Vinblastine | 1985 |
Role of methotrexate polyglutamates in methotrexate- and sequential methotrexate-5-fluorouracil-mediated cell kill.
Topics: Cell Survival; Drug Synergism; Fluorouracil; Humans; Leukemia, Experimental; Methotrexate; Peptides; Polyglutamic Acid | 1985 |
Cisplatin-containing chemotherapy in advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Vinblastine | 1985 |
Antibacterial activities of antineoplastic agents.
Topics: Antineoplastic Agents; Bacteria; Bleomycin; Doxorubicin; Etoposide; Fluorouracil; Methotrexate; Microbial Sensitivity Tests; Mitomycin; Mitomycins | 1985 |
[A new in vitro chemosensitivity test. Individualized chemotherapy against ovarian cancer and its clinical effect].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Child; Cisplatin; Colony-Forming Units Assay; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Nimustine; Nitrosourea Compounds; Ovarian Neoplasms; Tumor Stem Cell Assay | 1985 |
Pretreatment with chemotherapy in patients with advanced head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Drug Evaluation; Fluorouracil; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Oropharyngeal Neoplasms | 1985 |
Sequential methotrexate and 5-fluorouracil with bleomycin and cisplatin in the chemotherapy of advanced squamous cancer of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1986 |
[Evaluation of the sustained release of anticancer agents from silicone pellets].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Cytarabine; Delayed-Action Preparations; Fluorouracil; Humans; Methotrexate; Mitomycin; Mitomycins; Silicone Elastomers | 1985 |
Nursing implications related to chemotherapy for head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Vincristine | 1985 |
Effect of cancer chemotherapeutic drugs on radiation-induced lung damage in mice.
Topics: Animals; Antineoplastic Agents; Bleomycin; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Radiation; Doxorubicin; Fluorouracil; Lung; Male; Methotrexate; Mice; Mitomycin; Mitomycins; Radiation Injuries, Experimental; Time Factors | 1986 |
Carcinoma of the nasopharynx. An analysis of 91 cases and a comparison of differing treatment approaches.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Endoscopy; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Palpation; Random Allocation; Retrospective Studies | 1986 |
The efficacy of combined therapy with methotrexate and 5-fluorouracil from the view point of cellular PRPP level of L1210 cells and HeLa S3 cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; HeLa Cells; Humans; Leukemia L1210; Methotrexate; Mice; Pentosephosphates; Phosphoribosyl Pyrophosphate | 1985 |
Combined modality therapy utilizing a cisplatin combination for effective chemotherapy in patients with previously untreated head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Vincristine | 1986 |
Experimental studies on interactions of radiation and cancer chemotherapeutic drugs in normal tissues and a solid tumour.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carcinoma; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Fluorouracil; Male; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mitomycin; Mitomycins; Radiation Dosage; Radiotherapy; Time Factors | 1986 |
[Treatment of metastatic breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms; Cyclophosphamide; Dacarbazine; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prednisone; Random Allocation; Vinblastine; Vincristine | 1986 |
Long-term results of a pilot study for the treatment of advanced unresectable head and neck tumors by combination chemotherapy and split course radiotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydrocortisone; Leucovorin; Male; Methotrexate; Radiotherapy Dosage; Vincristine | 1986 |
[Non-cross-resistant sequential combination chemotherapy consisting of cis-diammine-dichloroplatinum (II) mainly, based on synchronization theory, in human bladder cancer xenografts in athymic nude mice].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cytarabine; Female; Fluorouracil; Humans; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Peplomycin; Urinary Bladder Neoplasms; Vincristine | 1986 |
[Combined chemotherapy and radiotherapy in recurrent tumors of the head and neck region].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy Dosage; Tegafur; Uracil | 1987 |
[Combination therapy of advanced choriocarcinoma--an analysis of 60 patients].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Choriocarcinoma; Combined Modality Therapy; Dactinomycin; Female; Fluorouracil; Humans; Lung Neoplasms; Mechlorethamine; Methotrexate; Pregnancy; Uterine Neoplasms; Vincristine | 1986 |
CDDP and 5-FU after prior VBM or VBM after prior CDDP and 5-FU in the management of recurrent squamous cell carcinoma of the head and neck?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Vincristine | 1986 |
[Critical remarks on chemotherapy of malignant tumors of the head and neck].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Staging | 1987 |
Multimodality treatment in anaplastic giant cell thyroid carcinoma.
Topics: Bleomycin; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Methotrexate; Thyroid Neoplasms | 1987 |
Effect of intracellular folate concentration on the modulation of 5-fluorouracil cytotoxicity by the elevation of phosphoribosylpyrophosphate in cultured human KB cells.
Topics: Adenosine; Carcinoma, Squamous Cell; Cell Survival; Fluorouracil; Folic Acid; Glucose; Humans; KB Cells; Leucovorin; Leukemia, Myeloid, Acute; Methotrexate; Nasopharyngeal Neoplasms; Pentosephosphates; Phosphoribosyl Pyrophosphate; Thymidine | 1987 |
Acute and late toxicity associated with sequential bleomycin-containing chemotherapy regimens and radiation therapy in the treatment of carcinoma of the nasopharynx.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Fluorouracil; Follow-Up Studies; Humans; Melphalan; Methotrexate; Nasopharyngeal Neoplasms; Neoplasm Staging; Prognosis; Radiotherapy Dosage | 1988 |
Chemotherapy for paranasal sinus carcinoma. A 10-year experience at Wayne State University.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Paranasal Sinus Neoplasms; Vincristine | 1988 |
Effect of various oxygenation conditions and fluosol-DA on cancer chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Bleomycin; Breast Neoplasms; Carbon Dioxide; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Combinations; Fibrosarcoma; Fluorocarbons; Fluorouracil; Humans; Hydroxyethyl Starch Derivatives; Male; Melphalan; Methotrexate; Mice; Mice, Inbred C3H; Mice, Nude; Neoplasm Transplantation; Neoplasms; Organoplatinum Compounds; Oxygen; Tumor Cells, Cultured | 1988 |
[Chemotherapy and partial surgery in epithelioma of the pharyngo-larynx].
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Cisplatin; Combined Modality Therapy; Fluorouracil; Humans; Laryngeal Neoplasms; Lymphatic Metastasis; Methotrexate; Pharyngeal Neoplasms | 1988 |
Induction cytotoxic chemotherapy: the significance of apparent complete clinical regression after using the Price Hill Schedule A protocol for squamous carcinoma of the head and neck.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrocortisone; Leucovorin; Male; Methotrexate; Middle Aged; Remission Induction; Vincristine | 1988 |
[Chemotherapy of carcinoma of the prostate and testis: experimental study in vivo and in vitro].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cell Line; Cisplatin; Cytarabine; Etoposide; Fluorouracil; Male; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Peplomycin; Prostatic Neoplasms; Testicular Neoplasms; Tumor Cells, Cultured; Tumor Stem Cell Assay; Vinblastine; Vincristine | 1988 |
Cytotoxicity of cisplatin and carboplatin used alone and in combination with the other anticancer drugs in the mouse embryo C3H10T1/2 cell line.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Cell Line; Cell Survival; Cisplatin; Drug Screening Assays, Antitumor; Fluorouracil; Methotrexate; Mice; Mice, Inbred C3H; Organoplatinum Compounds; Vincristine | 1988 |
Tumor lysis syndrome in nonhematopoietic neoplasms.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cisplatin; Dysgerminoma; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Testicular Neoplasms; Tumor Lysis Syndrome; Vinblastine | 1989 |
Phase I trial of N-(phosphonacetyl)-L-aspartate, methotrexate, and 5-fluorouracil with leucovorin rescue in patients with advanced cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Bone Marrow; Carcinoma, Squamous Cell; Colorectal Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Pentosephosphates; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate | 1989 |
Dipyridamole potentiates the growth-inhibitory action of methotrexate and 5-fluorouracil in human keratinocytes in vitro.
Topics: Cell Division; Dipyridamole; DNA; Drug Synergism; Epidermal Cells; Fluorouracil; Humans; Infant, Newborn; Keratins; Male; Methotrexate; Thymidine | 1989 |
[Treatment of squamous cell carcinoma of the head and neck with multi-drug chemotherapy and radiotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Peplomycin | 1989 |
[Factors modifying remission in cytostatic chemotherapy of squamous cell carcinoma recurrence in the area of the head and neck].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Palliative Care; Prognosis | 1989 |
Ifosfamide, methotrexate, and 5-fluorouracil in advanced pretreated breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Fluorouracil; Humans; Ifosfamide; Menopause; Mesna; Methotrexate; Middle Aged; Neoplasm Metastasis; Remission Induction; Time Factors | 1989 |
[Conservative treatment of malignant liver tumors].
Topics: Adult; Aged; Combined Modality Therapy; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Particle Accelerators; Radiotherapy Dosage; Tegafur | 1989 |
[Locoregional chemotherapy of liver tumors].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Infusion Pumps; Infusions, Intra-Arterial; Liver Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins | 1989 |
Evaluation of antitumor activity in a human breast tumor/nude mouse model with a special emphasis on treatment dose.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Mitomycins; Neoplasm Transplantation; Nimustine; Transplantation, Heterologous; Vinblastine | 1989 |
Arterial thrombosis associated with adjuvant chemotherapy for breast carcinoma: a Cancer and Leukemia Group B Study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Breast Neoplasms; Cerebrovascular Disorders; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Fluoxymesterone; Humans; Methotrexate; Middle Aged; Prednisone; Thiotepa; Thrombosis; Vinblastine; Vincristine | 1989 |
Preoperative irradiation with and without chemotherapy (MFL) in the treatment of primarily non-resectable adenocarcinoma of the rectum. Results from two consecutive studies.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Radiotherapy, High-Energy; Rectal Neoplasms | 1989 |
Primary medical therapy for operable breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Gonadotropin-Releasing Hormone; Hormones; Humans; Leuprolide; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Mitoxantrone; Tamoxifen | 1989 |
[Radiotherapy with neoadjuvant chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Hodgkin Disease; Humans; Male; Mechlorethamine; Methotrexate; Neoplasm Metastasis; Organoplatinum Compounds; Otorhinolaryngologic Neoplasms; Prednisone; Procarbazine; Random Allocation; Thiotepa; Vinblastine; Vincristine | 1989 |
5-Fluoropyrimidine-induced DNA damage in human colon adenocarcinoma and its augmentation by the nucleoside transport inhibitor dipyridamole.
Topics: Adenocarcinoma; Colonic Neoplasms; Dipyridamole; DNA; DNA Damage; Floxuridine; Fluorouracil; Humans; Methotrexate; Nucleosides; Tumor Cells, Cultured | 1989 |
[Two cases of gastrointestinal cancers with major responses to sequential methotrexate 5-FU plus 5'-DFUR].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Stomach Neoplasms | 1989 |
MTX-5-FU combination therapy compared to FUDR monotherapy in nude mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Humans; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous | 1989 |
Sequence-dependent enhancement of HCT-8 cell kill by trimetrexate and fluoropyrimidines: implications for the mechanism of this interaction.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colony-Forming Units Assay; Drug Interactions; Drug Synergism; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Methotrexate; Quinazolines; Trimetrexate; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1989 |
LHRH analogues in early breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Buserelin; Cyclophosphamide; Female; Fluorouracil; Goserelin; Humans; Methotrexate; Middle Aged | 1989 |
Overexpression of DNA replication and repair enzymes in cisplatin-resistant human colon carcinoma HCT8 cells and circumvention by azidothymidine.
Topics: Cell Line; Cisplatin; Colonic Neoplasms; DNA Polymerase I; DNA Polymerase II; DNA Repair; DNA Replication; Drug Resistance; Etoposide; Floxuridine; Fluorouracil; Humans; Methotrexate; Tetrahydrofolate Dehydrogenase; Thymidine Kinase; Thymidylate Synthase; Tumor Cells, Cultured; Zidovudine | 1989 |
[Effect of sequential MTX/5-FU therapy for a case of disseminated intravascular coagulation syndrome associated with recurrence of gastric cancer--a case report].
Topics: Adenocarcinoma, Scirrhous; Adult; Disseminated Intravascular Coagulation; Fluorouracil; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Stomach Neoplasms | 1989 |
5-Fluorouracil infusion and mitomycin combination chemotherapy in the management of patients with advanced non-small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Drug Evaluation; Female; Fluorouracil; Humans; Leucovorin; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycins; Neoplasm Staging | 1989 |
[Preoperative intensive chemotherapy of operable breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy, Radical; Methotrexate; Middle Aged; Preoperative Care | 1989 |
[Ablative hormone therapy and chemotherapy of metastatic breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Liver Neoplasms; Lymph Node Excision; Mastectomy; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Ovariectomy | 1989 |
Advanced prostatic carcinoma: pulmonary manifestations.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Fluorouracil; Humans; Lung; Lung Neoplasms; Lymphatic Metastasis; Male; Melphalan; Methotrexate; Middle Aged; Pleural Effusion; Prednisone; Prostatic Neoplasms; Radiography; Retrospective Studies; Vincristine | 1985 |
Effects of chemotherapeutic agents on the immune response. II.
Topics: Adrenal Cortex Hormones; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Bleomycin; Cyclosporins; Cytarabine; Fluorouracil; Humans; Immunity; Interferons; Mercaptopurine; Methotrexate; Naphthacenes | 1985 |
Effect of concentration and time of drug exposure on clonal growth of murine bladder cancer.
Topics: Animals; Antineoplastic Agents; Bleomycin; Cell Line; Cisplatin; Colony-Forming Units Assay; Disease Models, Animal; Doxorubicin; FANFT; Female; Fluorouracil; Maytansine; Methotrexate; Mice; Mice, Inbred C3H; Mitomycin; Mitomycins; Podophyllotoxin; Streptozocin; Time Factors; Trichothecenes; Tumor Stem Cell Assay; Urinary Bladder Neoplasms | 1985 |
beta-Thromboglobulin in patients with breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Beta-Globulins; beta-Thromboglobulin; Breast Neoplasms; Carcinoembryonic Antigen; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; History, 15th Century; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Radioimmunoassay; Vincristine | 1985 |
[Arterial infusion method: its theory and clinical application--dosage and regimen].
Topics: Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intra-Arterial; Methotrexate; Mitomycin; Mitomycins; Neoplasms | 1985 |
Postcricoid carcinoma: a retrospective study of 13 patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Hydroxyurea; Laryngeal Neoplasms; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Vincristine | 1985 |
Analysis of complete responders after initial treatment with chemotherapy in head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1985 |
A phase II trial of cyclophosphamide and adriamycin in refractory squamous cell carcinoma of the head and neck. An effective salvage regimen.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged | 1985 |
The concentration of 5-phosphoribosyl 1-pyrophosphate in monolayer tumor cells and the effect of various pyrimidine antimetabolites.
Topics: Animals; Aspartic Acid; Cell Line; Cells, Cultured; Fluorouracil; Humans; Methotrexate; Neoplasms; Ornithine Decarboxylase; Orotate Phosphoribosyltransferase; Pentosephosphates; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate | 1985 |
Impact of administration-related factors on outcome of adjuvant chemotherapy for primary breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Prognosis; Prospective Studies | 1989 |
[Therapeutic results and toxic side effects of the combination cytostasan, adriamycin and vincristine as second-line therapy of metastatic breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Nitrogen Mustard Compounds; Remission Induction; Vincristine | 1989 |
5-Fluorouracil inhibits dihydrofolate reductase precursor mRNA processing and/or nuclear mRNA stability in methotrexate-resistant KB cells.
Topics: Blotting, Northern; Cell Nucleus; Drug Resistance; Exons; Fluorouracil; Gene Amplification; Genes; Humans; Introns; KB Cells; Kinetics; Methotrexate; Plasmids; Restriction Mapping; RNA Precursors; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetrahydrofolate Dehydrogenase | 1989 |
Local postoperative morbidity following pre-operative irradiation in locally advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Length of Stay; Mastectomy, Radical; Mastectomy, Simple; Methotrexate; Prognosis; Quality of Life; Radiodermatitis; Radiotherapy; Staphylococcal Infections; Surgical Wound Infection; Vincristine; Wound Healing | 1989 |
Effect of subconjunctivally administered antineoplastics on experimentally induced intraocular malignant tumour.
Topics: Animals; Antineoplastic Agents; Conjunctiva; Cytarabine; Female; Fluorouracil; Injections; Iris Neoplasms; Melanoma, Experimental; Mercaptopurine; Methotrexate; Neoplasm Transplantation; Rabbits | 1989 |
[Various doses cisplatin combined with multi-drug chemotherapy of malignant solid tumors].
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Humans; Lomustine; Lung Neoplasms; Male; Melanoma; Melphalan; Methotrexate; Middle Aged; Neoplasms; Procarbazine; Testicular Neoplasms; Vincristine | 1989 |
Endocrine effects of adjuvant chemotherapy in premenopausal women: suggestions for the future.
Topics: Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Menopause; Meta-Analysis as Topic; Methotrexate; Tamoxifen | 1989 |
Critical review of adjuvant therapy in premenopausal patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Menopause; Meta-Analysis as Topic; Methotrexate; Middle Aged; Ovariectomy | 1989 |
Rehabilitation of patients with primary breast cancer: assessing the impact of adjuvant therapy.
Topics: Adult; Affective Symptoms; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Prospective Studies; Quality of Life; Socioeconomic Factors; Tamoxifen | 1989 |
Factors associated with local recurrence as a first site of failure following the conservative treatment of early breast cancer.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cohort Studies; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Risk Factors; Time Factors | 1989 |
Methotrexate increases the activation and cytotoxicity of 5-fluorouracil: detected by 19F n.m.r. in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biotransformation; Carcinoma 256, Walker; Female; Fluorouracil; Magnetic Resonance Spectroscopy; Methotrexate; Rats; Rats, Inbred Strains | 1989 |
Mitoxantrone, methotrexate, and 5-fluorouracil (MMF) in hormone-refractory advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitoxantrone; Prospective Studies | 1989 |
Sequential high dose methotrexate, 5-fluorouracil and folinic acid does not improve response rates in advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Lung Neoplasms; Male; Methotrexate; Middle Aged; Remission Induction | 1989 |
[Combination chemotherapy of CPM-MTX-5-FU in non-resectable and recurrent cancer patients].
Topics: Anorexia; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration Schedule; Drug Evaluation; Fatigue; Fluorouracil; Humans; Leukopenia; Methotrexate; Nausea; Neoplasm Recurrence, Local; Neoplasms; Remission Induction; Stomach Neoplasms | 1989 |
Phase II study of adriamycin with sequential methotrexate and 5-fluorouracil (AMF) in gastric carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 1989 |
Sequential moderate-dose methotrexate and 5-fluorouracil in advanced gastric adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Pilot Projects; Stomach Neoplasms | 1989 |
Growth and chemosensitivity of human head and neck cancers implanted under the kidney capsule of cyclosporine-immunosuppressed mice.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Cyclosporins; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Mice; Subrenal Capsule Assay | 1989 |
The effect of sequential methotrexate and 5-fluorouracil in patients with recurrent head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis | 1989 |
Potentiation of antimetabolite antitumor activity in vivo by dipyridamole and amphotericin B.
Topics: Amphotericin B; Animals; Antimetabolites, Antineoplastic; Dipyridamole; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Lung Neoplasms; Male; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Sarcoma 180; Uterine Cervical Neoplasms | 1989 |
[The use of neo-adjuvant chemotherapy in the treatment of carcinoma of the upper aero-digestive tract].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate | 1989 |
Mitoxantrone as first-salvage chemotherapy in relapsed breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Heart; Humans; Methotrexate; Middle Aged; Mitoxantrone | 1989 |
Secondary acute myelocytic leukemia after adjuvant therapy for early-stage breast carcinoma. A new complication of cyclophosphamide, methotrexate, and 5-fluorouracil therapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Leukemia, Myeloid, Acute; Methotrexate | 1989 |
Advanced gastric cancer: a new combined surgical and oncological approach.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Fluorouracil; Follow-Up Studies; Gastrectomy; Humans; Male; Methotrexate; Middle Aged; Reoperation; Stomach Neoplasms | 1989 |
Inhibition by methotrexate of the stable incorporation of 5-fluorouracil into murine bone marrow DNA.
Topics: Animals; Bone Marrow; Chromatography, High Pressure Liquid; DNA; Fluorouracil; Methotrexate; Mice | 1989 |
Inflammatory carcinoma of the breast: treatment results on 107 patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Prognosis; Retrospective Studies | 1989 |
Phase II trial of methotrexate-FAM (m-FAM) in adenocarcinoma of unknown primary.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasms, Unknown Primary | 1989 |
Effect of antineoplastic drugs and estradiol on leucine uptake and proliferation of Ehrlich tumor cells.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Division; Doxorubicin; Estradiol; Fluorouracil; Leucine; Methotrexate; Mice; Mice, Inbred Strains; Tamoxifen | 1989 |
Premenopausal breast cancer patients treated with conservative surgery, radiotherapy and adjuvant chemotherapy have a low risk of local failure.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Mastectomy, Segmental; Methotrexate; Neoplasm Recurrence, Local; Prognosis; Risk Factors | 1989 |
Accumulation of tetrahydrofolates in human plasma after leucovorin administration.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Humans; Injections, Intravenous; Kinetics; Leucovorin; Methotrexate; Oxidation-Reduction; Reference Values; Tetrahydrofolates | 1989 |
[Experimental study of 5-FU + leucovorin therapy by continuous arterial infusion].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Infusion Pumps; Infusions, Intra-Arterial; Infusions, Intravenous; Leucovorin; Liver; Liver Neoplasms, Experimental; Methotrexate; Rabbits; Tissue Distribution | 1989 |
Analysis of drug in tissue homogenates by high performance liquid chromatography with direct injection and column switching.
Topics: Animals; Cell-Free System; Chromatography, High Pressure Liquid; Fluorouracil; Kidney; Liver; Methotrexate; Mice; Myocardium; Organelles; Pharmaceutical Preparations; Procainamide; Propranolol | 1989 |
[Evaluation of combined chemotherapy including high-dose cisplatin in the treatment of malignant tumors].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cisplatin; Cyclophosphamide; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Vincristine | 1987 |
[The role of thymidylate synthetase in sequential dose of MTX and 5-FU in the advanced scirrhous type gastric cancer].
Topics: Adenocarcinoma, Scirrhous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Stomach Neoplasms; Thymidylate Synthase | 1988 |
Adjuvant chemotherapy in early breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Prognosis | 1986 |
Prospective evaluation of chronic cardiotoxicity due to high-dose epirubicin or combination chemotherapy with cyclophosphamide, methotrexate, and 5-fluorouracil.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Heart; Hemodynamics; Humans; Methotrexate; Middle Aged; Stroke Volume | 1989 |
Low-dose continuous infusion 5-fluorouracil. Evaluation in advanced breast carcinoma.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Receptors, Estrogen; Vincristine | 1989 |
Jaundice and intrahepatic cholestasis following high-dose megestrol acetate for breast cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bilirubin; Breast Neoplasms; Cholestasis, Intrahepatic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Jaundice; Mastectomy, Radical; Megestrol; Megestrol Acetate; Methotrexate; Prednisone; Vincristine | 1989 |
Side effects and emotional distress during cancer chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Longitudinal Studies; Lymphoma; Male; Mechlorethamine; Methotrexate; Prednisone; Procarbazine; Stress, Psychological; Vincristine | 1989 |
Cyclophosphamide, methotrexate, and 5-fluorouracil in a three-drug admixture. Phase I trial of 14-day continuous ambulatory infusion.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration Schedule; Drug Combinations; Drug Evaluation; Drug Stability; Fluorouracil; Humans; Infusions, Intravenous; Leukopenia; Methotrexate; Neoplasms; Thrombocytopenia | 1989 |
Acquired protein C deficiency in patients with breast cancer receiving cyclophosphamide, methotrexate, and 5-fluorouracil.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Coagulation Factors; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Protein C Deficiency; Vincristine | 1989 |
Effective systemic therapy for spinal epidural metastases from breast carcinoma.
Topics: Adult; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Epidural Neoplasms; Female; Fluorouracil; Humans; Hydrocortisone; Methotrexate; Middle Aged; Radiography | 1989 |
[Chemotherapy of advanced prostate cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bromocriptine; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cyproterone; Cyproterone Acetate; Fluorouracil; Humans; Male; Methotrexate; Neoplasm Staging; Orchiectomy; Prognosis; Prostatic Neoplasms | 1986 |
DNA lesions in human neoplastic cells and cytotoxicity of 5-fluoropyrimidines.
Topics: Aphidicolin; Cell Survival; Centrifugation, Density Gradient; Diterpenes; DNA, Neoplasm; Floxuridine; Fluorouracil; Humans; Methotrexate; Neoplasms; Time Factors | 1986 |
Enhancement of the effects of 5-fluorouracil.
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Drug Synergism; Floxuridine; Fluorouracil; Humans; Methotrexate; Neoplasms; Pyrimidines | 1986 |
Pharmacological modulation of photodynamic therapy with hematoporphyrin derivative and light.
Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Synergism; Fluorouracil; Hematoporphyrin Derivative; Hematoporphyrins; Lung Neoplasms; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Phototherapy; Radiation Tolerance; Thiotepa; Vincristine | 1987 |
Acute effects of various chemotherapeutic combinations on hypophyseal and pineal hormone secretions in cancer patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; beta-Endorphin; Cisplatin; Cyclophosphamide; Doxorubicin; Endorphins; Epirubicin; Female; Fluorouracil; Humans; Hydrocortisone; Male; Melatonin; Methotrexate; Neoplasms; Pineal Gland; Pituitary Gland, Anterior; Pituitary Hormones, Anterior; Secretory Rate; Vincristine | 1987 |
[Combination chemotherapy with 3 or 4 drugs on human breast and gastrointestinal cancer xenografts in nude mice (II)].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Colonic Neoplasms; Cyclophosphamide; Doxorubicin; Female; Floxuridine; Fluorouracil; Humans; Methotrexate; Mice; Mice, Nude; Mitomycin; Mitomycins; Neoplasm Transplantation; Stomach Neoplasms; Tegafur; Vindesine | 1987 |
Adjuvant therapy for breast cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Tamoxifen | 1987 |
Chemotherapy for breast cancer decreases plasma protein C and protein S.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Female; Fluorouracil; Glycoproteins; Humans; Methotrexate; Protein C; Protein S | 1988 |
[Rationale and current results of loco-regional chemotherapy in hepatic metastases of colorectal carcinoma].
Topics: Antineoplastic Agents; Carmustine; Cisplatin; Colorectal Neoplasms; Doxorubicin; Floxuridine; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Methotrexate; Mitomycin; Mitomycins; Models, Biological; Prognosis | 1987 |
Cisplatin, methotrexate, and 5-fluorouracil combination chemotherapy for advanced ovarian cancer.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Drug Evaluation; Endometriosis; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms | 1985 |
Stem cell defects after cytoreductive therapy in man.
Topics: Animals; Antineoplastic Agents; Blood Cells; Bone Marrow; Breast Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Hematopoietic Stem Cells; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Nitrosourea Compounds; Regeneration; Reticulocytes; Vincristine | 1985 |
[Sequential chemotherapy with low-dose methotrexate and 5-fluorouracil in advanced gastric cancer].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Gastroscopy; Humans; Male; Methotrexate; Middle Aged; Stomach Neoplasms; Tomography, X-Ray Computed | 1985 |
The management of nonmetastatic locally advanced breast cancer using primary induction chemotherapy with hormonal synchronization followed by radiation therapy with or without debulking surgery.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Estrogens, Conjugated (USP); Female; Fluorouracil; Humans; Leucovorin; Methotrexate; Middle Aged; Neoplasm Staging; Radiography; Random Allocation; Tamoxifen | 1985 |
The response to further chemotherapy in patients with carcinoma of the breast who progressed while receiving adjuvant therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Tamoxifen; Vincristine | 1985 |
[Cytostatic treatment of pseudomyxoma peritonei].
Topics: Adenocarcinoma, Mucinous; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms; Peritoneal Neoplasms | 1985 |
Modulation of oestrogen excretion profiles by adjuvant chemotherapy in pre- and postmenopausal breast cancer.
Topics: Adrenal Cortex; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chromatography, High Pressure Liquid; Cyclophosphamide; Estrogens; Estrogens, Catechol; Female; Fluorouracil; Gas Chromatography-Mass Spectrometry; Humans; Menopause; Methotrexate; Middle Aged; Time Factors | 1985 |
[Chromosomal studies in patients with trophoblastic diseases before and after chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, Human, 1-3; Female; Fluorouracil; Humans; Methotrexate; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms | 1986 |
Two cases with objective complete response to neo-adjuvant chemotherapy of breast carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate | 1986 |
Impaired primary, but not secondary, immune response in breast cancer patients under adjuvant chemotherapy.
Topics: Adult; Antibodies, Viral; Antibody Formation; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Encephalitis Viruses, Tick-Borne; Female; Fluorouracil; Humans; Immunologic Memory; Methotrexate; Middle Aged; Vaccination; Viral Vaccines | 1986 |
Treatment of locally advanced breast cancer using primary induction chemotherapy with hormonal synchronization followed by radiation therapy with or without debulking surgery.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Estrogens, Conjugated (USP); Female; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Preoperative Care; Tamoxifen | 1986 |
Cytoxan, epirubicin, methotrexate and 5-fluorouracil with hormonal synchronization (tamoxifen/premarin) in advanced breast cancer. Preliminary results.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Epirubicin; Estrogens, Conjugated (USP); Female; Fluorouracil; Hormones; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Tamoxifen | 1986 |
Neoadjuvant chemotherapy in the combined modality approach of locally advanced nonmetastatic breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Estrogens, Conjugated (USP); Fluorouracil; Heart Failure; Humans; Leucovorin; Leukopenia; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Tamoxifen | 1987 |
Five-year survival following chemotherapy of non-small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Doxorubicin; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prognosis; Vincristine | 1987 |
Chemo- and immunotherapy of an adenovirus-induced transplantable sarcoma in hamsters.
Topics: Adenoviridae Infections; Alkylating Agents; Animals; Antimetabolites; Cricetinae; Cyclophosphamide; Female; Fluorouracil; Immunotherapy; Male; Melphalan; Mercaptopurine; Mesocricetus; Methotrexate; Mycobacterium bovis; Neoplasm Transplantation; Sarcoma, Experimental; Semustine | 1987 |
The effect of chemotherapy on the morphology of human breast carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cyclophosphamide; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Time Factors | 1987 |
[Antitumor effect of interferons with chemotherapeutic agents].
Topics: Antineoplastic Agents; Cell Line; Cells, Cultured; Cisplatin; Drug Therapy, Combination; Fluorouracil; Humans; Interferon Type I; Interferon-gamma; Methotrexate; Mitomycin; Mitomycins; Pancreatic Neoplasms; Stomach Neoplasms | 1986 |
[Combined effect of interferons alpha, beta and gamma on tumor growth in vitro].
Topics: Animals; Cell Line; Cells, Cultured; Drug Therapy, Combination; Fluorouracil; Humans; Interferon Type I; Interferon-gamma; Methotrexate; Mice; Pancreatic Neoplasms; Stomach Neoplasms | 1986 |
[Choice of second-line chemotherapy for advanced breast cancer based on the chemosensitivity assay by in vitro colony assay].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colony-Forming Units Assay; Doxorubicin; Drug Resistance; Female; Fluorouracil; Humans; In Vitro Techniques; Methotrexate; Mitomycin; Mitomycins; Naphthacenes; Tumor Stem Cell Assay | 1986 |
Hexamethylmelamine, methotrexate, 5-fluorouracil as second line chemotherapy after platinum for epithelial ovarian malignancies.
Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Hormones; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms; Peptichemio | 1986 |
[Chemotherapy in 143 advanced epithelial cancers of the ovary. Experience at the Hôtel-Dieu of Quebec and Hôpital Saint-Antoine (Paris)].
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Ovarian Neoplasms | 1986 |
An aggressive, sequential combination chemotherapy regimen in the treatment of metastatic colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasm Metastasis; Rectal Neoplasms; Vincristine | 1986 |
Prolactin response to thyrotropin-releasing hormone in early and advanced human breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prolactin; Thyrotropin-Releasing Hormone | 1986 |
[Subrenal capsule assay for chemosensitivity testing].
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Colony-Forming Units Assay; Cyclophosphamide; Doxorubicin; Drug Evaluation, Preclinical; Fluorouracil; Humans; Methotrexate; Mice; Mitomycin; Mitomycins; Neoplasm Transplantation; Stomach Neoplasms; Tumor Stem Cell Assay | 1987 |
[Improved quality of life in a patient with Borrmann type 4 gastric cancer treated with combination chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Picibanil; Prognosis; Quality of Life; Stomach Neoplasms; Tegafur; Uracil | 1987 |
Cyclophosphamide, methotrexate,5-fluorouracil, alternating with adriamycin and mitomycin C in metastatic breast cancer: a pilot study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasm Metastasis; Pilot Projects | 1987 |
In vitro assessment of antimicrobial agents against Toxoplasma gondii.
Topics: Animals; Anti-Infective Agents; Cell Line; Clindamycin; Drug Resistance; Eflornithine; Fluorouracil; Leucomycins; Methotrexate; Organometallic Compounds; Pyrimethamine; Rats; Spiro Compounds; Sulfadiazine; Toxoplasma | 1988 |
Metabolites of 5-fluorouracil in plasma and urine, as monitored by 19F nuclear magnetic resonance spectroscopy, for patients receiving chemotherapy with or without methotrexate pretreatment.
Topics: Aged; beta-Alanine; Blood Proteins; Chromatography, High Pressure Liquid; Female; Fluorides; Fluorouracil; Humans; Kinetics; Magnetic Resonance Spectroscopy; Male; Methotrexate; Middle Aged; Neoplasms; Protein Binding | 1988 |
Anticancer drugs: second malignancies--risk reduction.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Fluorouracil; Male; Mesna; Methotrexate; Neoplasms, Multiple Primary; Rats; Vincristine | 1987 |
Results of a conservative treatment combining induction (neoadjuvant) and consolidation chemotherapy, hormonotherapy, and external and interstitial irradiation in 98 patients with locally advanced breast cancer (IIIA-IIIB).
Topics: Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Breast Neoplasms; Cobalt Radioisotopes; Combined Modality Therapy; Doxorubicin; Evaluation Studies as Topic; Fluorouracil; Humans; Iridium Radioisotopes; Methotrexate; Prednisone; Radioisotope Teletherapy; Remission Induction; Tamoxifen; Thiotepa; Vinblastine | 1988 |
The treatment of advanced ovarian carcinoma (I): clinical variables associated with prognosis.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Hysterectomy; Methotrexate; Ovarian Neoplasms; Ovariectomy; Postoperative Care; Prognosis; Regression Analysis | 1988 |
Combined treatment in carcinoma of the nasopharynx.
Topics: Actuarial Analysis; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Methotrexate; Mitomycin; Mitomycins; Nasopharyngeal Neoplasms; Radioisotope Teletherapy; Radiotherapy Dosage | 1988 |
Radiotherapy for the prevention of local-regional recurrence in high risk patients post mastectomy receiving adjuvant chemotherapy.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Postoperative Care; Prednisone; Radiotherapy, High-Energy; Retrospective Studies; Risk Factors | 1988 |
[Inflammatory breast carcinoma--possibilities and results of surgical treatment and adjuvant chemotherapy, especially when done preoperatively].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Metastasis; Preoperative Care; Tegafur; Time Factors | 1988 |
Six-year results of a multimodality treatment strategy for locally advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Mastectomy, Modified Radical; Methotrexate; Middle Aged; Radiotherapy, High-Energy; Tamoxifen | 1988 |
Thermochemotherapy in vivo of a C3H mouse mammary carcinoma: single fraction heat and drug treatment.
Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Hyperthermia, Induced; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mice, Inbred C3H; Mitomycin; Mitomycins; Time Factors; Vincristine | 1988 |
[Secondary effects of adjuvant therapy].
Topics: Alopecia; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Cystitis; Doxorubicin; Drug Eruptions; Female; Fluorouracil; Heart; Humans; Methotrexate; Mitolactol; Mitomycins; Neoplasms | 1985 |
Combination chemotherapy with 5-fluorouracil, oral Idarubicin, and cyclophosphamide (FIC) in metastatic breast cancer--an open phase II study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Daunorubicin; Drug Evaluation; Fluorouracil; Humans; Idarubicin; Methotrexate; Prednisone; Vincristine | 1988 |
[Adjuvant chemotherapy and mastectomy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged | 1988 |
Synergistic cytotoxicity between dimethyl sulfoxide and antineoplastic agents against ovarian cancer in vitro.
Topics: Anthraquinones; Antineoplastic Agents; Cisplatin; Dimethyl Sulfoxide; Doxorubicin; Drug Synergism; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms; Tumor Cells, Cultured; Vinblastine | 1988 |
Sequential multiagent chemotherapy incorporating cisplatin, doxorubicin, and cyclophosphamide in the treatment of metastatic breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Fluorouracil; Follow-Up Studies; Humans; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Receptors, Estrogen | 1988 |
Improving the prognostic value of DNA flow cytometry in breast cancer by combining DNA index and S-phase fraction. A proposed classification of DNA histograms in breast cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; DNA, Neoplasm; Female; Flow Cytometry; Fluorouracil; Follow-Up Studies; Humans; Interphase; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Receptors, Estrogen; Receptors, Progesterone | 1988 |
Adjuvant chemotherapy with and without radiotherapy in stage II breast cancer.
Topics: Actuarial Analysis; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Postoperative Period; Retrospective Studies | 1988 |
A phase II study of sequential methotrexate and 5-fluorouracil in colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Drug Evaluation; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local | 1988 |
Treatment of esthesioneuroblastoma with chemotherapy: a report of two cases.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; Male; Methotrexate; Nasopharyngeal Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral | 1988 |
[Results of a controlled clinical protocol in the treatment of patients with operable breast carcinoma with positive axillary lymph nodes. Comparison of a chemotherapeutic regimen with a chemo-immunotherapeutic regimen].
Topics: Adjuvants, Immunologic; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Thymus Extracts | 1988 |
[Non-adjuvant chemotherapy in the complex treatment of breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Irradiation; Mastectomy, Radical; Methotrexate; Middle Aged; Preoperative Care; Vincristine | 1988 |
[Results of combination chemotherapy in advanced urothelial cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Urologic Neoplasms | 1988 |
[Chemotherapy of gastric cancer using a MAF combination].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Stomach Neoplasms | 1988 |
Folinic acid effect on 5-fluorouracil kinetics in vivo.
Topics: Animals; Drug Interactions; Female; Fluorouracil; Leucovorin; Methotrexate; Mice | 1988 |
[Concept of treatment of metastatic breast cancer outside university clinics: description of the method and evaluation of efficacy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cancer Care Facilities; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Neoplasm Metastasis | 1987 |
The efficacy of combined chemotherapy and radiotherapy in advanced non-metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging | 1988 |
Mechanisms of cross-resistance to methotrexate and 5-fluorouracil in an A2780 human ovarian carcinoma cell subline resistant to cisplatin.
Topics: Biological Transport; Cell Division; Cell Line; Cisplatin; Drug Resistance; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms; Thymidylate Synthase; Tumor Cells, Cultured | 1988 |
In vitro inhibition of lens epithelial cell proliferation and migration.
Topics: Animals; Cataract Extraction; Cell Division; Cell Movement; Colchicine; Culture Techniques; Cytochalasin B; Daunorubicin; Dexamethasone; Doxorubicin; Epithelial Cells; Fluorouracil; Lens, Crystalline; Lenses, Intraocular; Methotrexate; Rabbits | 1988 |
The effect of prior adjuvant chemotherapy on survival in metastatic breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Receptors, Estrogen; Retrospective Studies; Tamoxifen; Vincristine | 1988 |
Integration of full-dose adjuvant chemotherapy with definitive radiotherapy for primary breast cancer: four-year update.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Recurrence, Local; Prednisone | 1988 |
Sequential administration of methotrexate, cisplatin, and 5-fluorouracil in multimodal therapy for locally advanced head and neck cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1988 |
A phase II clinical trial of flutamide in the treatment of advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Injections, Intravenous; Methotrexate; Nausea; Pilot Projects; Vomiting | 1988 |
Sample loss during measurement of airborne antineoplastic agents.
Topics: Air Movements; Air Pollutants, Occupational; Antineoplastic Agents; Chromatography, High Pressure Liquid; Environment, Controlled; Filtration; Fluorouracil; Glass; Methotrexate; Specimen Handling; Temperature | 1988 |
Effect of chemotherapy on gonadal function in women with breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Female; Fluorouracil; Hormones; Humans; Methotrexate; Ovary | 1988 |
[The clinical and histological effect of preoperative combination chemotherapy with low dose MTX.5-FU in oral cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Preoperative Care | 1988 |
Weight gain in women with localized breast cancer--a descriptive study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Ovariectomy; Prednisone; Prognosis; Retrospective Studies; Time Factors | 1988 |
Low-dose mitomycin and weekly low-dose doxorubicin combination chemotherapy for patients with metastatic breast carcinoma previously treated with cyclophosphamide, methotrexate, and 5-fluorouracil.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Mitomycins; Neoplasm Metastasis | 1988 |
Comments on primary and adjuvant treatments of breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Node Excision; Lymphatic Metastasis; Methotrexate; Prognosis; Recurrence | 1988 |
Adjuvant chemotherapy in premenopausal patients with primary breast cancer; relation to drug-induced amenorrhoea, age and the progesterone receptor status of the tumour.
Topics: Adult; Age Factors; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Menopause; Methotrexate; Middle Aged; Receptors, Progesterone | 1988 |
The use of diamox in the sequential methotrexate-5-fluorouracil therapy of advanced gastrointestinal cancer.
Topics: Acetazolamide; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Gastrointestinal Neoplasms; Humans; Kidney Diseases; Methotrexate | 1988 |
Collagen gel culture of rat mammary tumor cells as an assay system for determination of therapeutic efficacy of chemotherapeutic agents.
Topics: Animals; Collagen; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Female; Fluorouracil; Gels; Mammary Neoplasms, Experimental; Methotrexate; Rats; Rats, Inbred Strains; Tumor Cells, Cultured | 1988 |
Adjuvant chemotherapy for breast cancer: 20 years experience using CVFMP chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoembryonic Antigen; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Vincristine | 1988 |
[Study on microspheres for embolization of the hepatic artery].
Topics: Animals; Delayed-Action Preparations; Dogs; Embolization, Therapeutic; Fluorouracil; Gelatin; Hepatic Artery; Liver Neoplasms; Methotrexate; Microspheres; Polyvinyl Alcohol | 1988 |
Salvage treatment with intermediate-dose methotrexate and 5-fluorouracil in metastatic breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis | 1988 |
Modulation of induced resistance to adriamycin in two human breast cancer cell lines with tamoxifen or perhexiline maleate.
Topics: Breast Neoplasms; Cell Line; Doxorubicin; Drug Interactions; Drug Resistance; Fluorouracil; Humans; Melphalan; Methotrexate; Perhexiline; Tamoxifen; Tumor Stem Cell Assay; Vinblastine | 1988 |
Prednimustine, methotrexate, 5-fluorouracil, mitoxantrone and tamoxifen for advanced breast cancer in postmenopausal women. A phase II trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Evaluation; Female; Fluorouracil; Follow-Up Studies; Humans; Menopause; Methotrexate; Middle Aged; Mitoxantrone; Prednimustine; Tamoxifen | 1988 |
[Immunomodulating effects of indomethacin in breast cancer].
Topics: Adjuvants, Immunologic; Adult; Antibody Formation; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Immunity, Cellular; Indomethacin; Methotrexate; Middle Aged; Preoperative Care; Vincristine | 1987 |
Sensitivity of newly established colorectal cell lines to cytotoxic drugs and monoclonal antibody drug conjugates.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Antineoplastic Agents; Cell Survival; Colonic Neoplasms; Daunorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Methotrexate; Rectal Neoplasms; Tumor Cells, Cultured | 1987 |
Suppression of in vitro peripheral blood lymphocyte mitogenesis by cytotoxic drugs commonly used in the treatment of breast cancer: a comparative study.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Cells, Cultured; Cyclophosphamide; DNA; Doxorubicin; Fluorouracil; Humans; Lymphocytes; Methotrexate; Middle Aged; Mitosis; Phytohemagglutinins; Vincristine | 1987 |
[The influence of post-operative radiotherapy on adjuvant chemotherapy: an analysis of stage III breast cancer patients].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Evaluation Studies as Topic; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Postoperative Care; Retrospective Studies | 1987 |
Dynamic hormonal chemotherapy in advanced metastatic breast carcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Fluorouracil; Gonadal Steroid Hormones; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1986 |
The 6 day subrenal capsule assay is of no value with primary surgical explants from gastric cancer.
Topics: Adenocarcinoma; Animals; Cisplatin; Doxorubicin; Drug Evaluation, Preclinical; Epirubicin; Fluorouracil; Humans; Kidney; Methotrexate; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Stomach Neoplasms | 1986 |
Tumor uptake of 5-fluorouracil, methotrexate, and adriamycin vs gallium.
Topics: Animals; Carcinoma 256, Walker; Doxorubicin; Female; Fluorouracil; Gallium Radioisotopes; Kinetics; Methotrexate; Radionuclide Imaging; Rats; Rats, Inbred Strains; Tissue Distribution; Tritium | 1986 |
[Intra-aortic infusion therapy with sequential methotrexate (MTX) and 5-FU in advanced gastric carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aorta; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Injections, Intra-Arterial; Leucovorin; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 1986 |
Sequential methotrexate--5-FU--leucovorin (MFL) in advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms | 1986 |
[Chemotherapy of advanced and recurrent colorectal cancer].
Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Hyperthermia, Induced; Infusions, Intra-Arterial; Leucovorin; Methotrexate; Neoplasm Recurrence, Local; Rectal Neoplasms | 1986 |
Sequential methotrexate, 5-fluorouracil, and calcium leucovorin in colorectal carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Rectal Neoplasms | 1986 |
Chemoendocrine therapy with prolonged estrogen priming in advanced breast cancer: endocrine pharmacokinetics and toxicity.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Estradiol; Estrone; Female; Fluorouracil; Humans; Kinetics; Leucovorin; Methotrexate; Middle Aged; Tamoxifen | 1987 |
Continuous 5-fluorouracil infusion and pulse methotrexate/leucovorin for colorectal adenocarcinoma. A report of excessive toxicity.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Drug Synergism; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged; Rectal Neoplasms | 1987 |
[Biochemical modulation with sequential methotrexate (MTX)-5-fluorouracil (5-FU) treatment].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Injections, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 1987 |
[Methotrexate and 5-fluorouracil with leucovorin therapy in advanced gastric cancer: the enhancement of 5-fluorouracil antitumor activity by leucovorin].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Synergism; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 1987 |
Sequential 5-fluorouracil and methotrexate. Negative experience in metastatic colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Rectal Neoplasms; Time Factors | 1987 |
Combination chemotherapy and systemic irradiation consolidation for poor prognosis breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Hematologic Diseases; Humans; Methotrexate; Prednisone; Prognosis; Vinblastine; Whole-Body Irradiation | 1987 |
Chemotherapy of advanced gastric carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Cytarabine; Fluorouracil; Humans; Methotrexate; Stomach Neoplasms | 1986 |
Stimulus control of anticipatory nausea in cancer chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorpromazine; Combined Modality Therapy; Conditioning, Classical; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Nausea; Perceptual Masking; Taste | 1987 |
[Complete regression of breast cancer and its lung metastases after chemohormonotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Tamoxifen | 1986 |
[Value of adjuvant chemotherapy in infiltrating tumors of the bladder].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Retrospective Studies; Urinary Bladder Neoplasms | 1986 |
[The metabolism of high-molecular-weight substances in cells and the effect of anticancer drugs].
Topics: Animals; DNA Repair; DNA Replication; Fluorouracil; Leukemia L1210; Methotrexate; Mice; Molecular Weight; RNA, Messenger; RNA, Ribosomal | 1987 |
A cytotoxic DNA precursor is taken up selectively by human cancer xenografts.
Topics: Animals; Choriocarcinoma; Colon; DNA; Female; Fluorouracil; Humans; Hydroxyurea; Idoxuridine; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Nucleic Acid Precursors; Pregnancy; Uterine Neoplasms | 1987 |
[Sequential administration of methotrexate and 5-fluorouracil in epidermoid carcinomas of the head and neck. Results of a prospective study].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies | 1986 |
Sequential methotrexate and 5-fluorouracil in advanced ovarian carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascites; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms | 1987 |
[Preclinical and clinical studies of sequential therapy with methotrexate and 5 fluorouracil in breast cancer].
Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Administration Schedule; Drug Evaluation; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Mammary Neoplasms, Experimental; Methotrexate; Middle Aged; Rats; Rats, Inbred Strains | 1986 |
Combination chemotherapy in the treatment of adenocarcinoma of unknown primary origin.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasms, Unknown Primary; Vincristine | 1987 |
[Transcatheter therapy of cancer of the urinary bladder].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Urinary Bladder Neoplasms | 1987 |
Combination chemotherapy for the treatment of diffuse aggressive lymphomas: F-MACHOP update.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Fluorouracil; Humans; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Prognosis; Vincristine | 1987 |
High-dose metoclopramide and dexamethasone as an antiemetic in outpatients receiving chemotherapy for breast cancer. Second study.
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Dexamethasone; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Metoclopramide; Middle Aged; Nausea; Vomiting | 1987 |
[Analysis of alveolitis (pneumonitis) as a complication of cytostatic (CMF) therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Pneumonia; Pulmonary Alveoli; Pulmonary Fibrosis | 1987 |
[Chemotherapy of metastatic gastric cancer--x-ray follow-up].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Fluorouracil; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Radiography; Stomach Neoplasms | 1987 |
Effects of cyclophosphamide alone and scheduled methotrexate-5-fluorouracil combination chemotherapy on transplantable R-3327 prostatic adenocarcinoma in F1 hybrid male rat.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Fluorouracil; Male; Methotrexate; Neoplasm Transplantation; Prostatic Neoplasms; Rats | 1987 |
Permeability of latex and polyvinyl chloride gloves to fluorouracil and methotrexate.
Topics: Dialysis; Fluorouracil; Kinetics; Latex; Methotrexate; Permeability; Polyvinyl Chloride; Protective Clothing | 1987 |
[Sequential methotrexate-5-fluorouracil (MTX-5-FU) treatment of patients with advanced gastric and colorectal cancer. Sequential Methotrexate-5-FU Study Group].
Topics: Adult; Aged; Colonic Neoplasms; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Rectal Neoplasms; Stomach Neoplasms | 1987 |
Sequential combination chemotherapy of high-grade non-Hodgkin's lymphoma with 5-fluorouracil, methotrexate, cytosine-arabinoside, cyclophosphamide, doxorubicin, vincristine, and prednisone (F-MACHOP).
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Vincristine | 1987 |
Clinical trials in advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Methotrexate; Prognosis; Vincristine | 1987 |
Ovarian function and adjuvant chemotherapy for early breast cancer.
Topics: Adult; Age Factors; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Hormones; Humans; Menopause; Methotrexate; Middle Aged | 1987 |
Use of mitoxantrone-based combination chemotherapy regimens as first-line treatment for advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Metastasis | 1987 |
Progesterone receptor activity and relapse-free survival in patients with primary breast cancer: the role of adjuvant chemotherapy.
Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Prognosis; Receptors, Progesterone | 1987 |
[Ovarian function and recurrence in adjuvant chemotherapy of breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Methotrexate; Neoplasm Recurrence, Local; Ovarian Function Tests; Receptors, Estrogen; Receptors, Progesterone | 1987 |
Significance of plasma retinol binding protein levels in recurrence of breast tumors in women.
Topics: Antineoplastic Combined Chemotherapy Protocols; beta Carotene; Breast Neoplasms; Carotenoids; Cisplatin; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Proteins; Neoplasm Recurrence, Local; Prealbumin; Retinol-Binding Proteins; Retinol-Binding Proteins, Plasma; Vitamin A | 1987 |
Adjuvant chemotherapy with adriamycin, fluorouracil, cyclophosphamide, methotrexate, with or without tamoxifen in operable breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1987 |
[Rational combinations of hormonal and cytostatic agents in disseminated forms of breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Cyclophosphamide; Diethylstilbestrol; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Metastasis; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1987 |
Escalating doses of sequential methotrexate and 5-fluorouracil, doxorubicin, and vincristine for the treatment of metastatic breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Vincristine | 1987 |
Neoadjuvant chemotherapy before definitive treatment for stage III carcinoma of the breast.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Staging; Postoperative Care; Preoperative Care; Tamoxifen; Time Factors | 1987 |
Interactions of methotrexate and cyclophosphamide with the pharmacokinetics of 5-fluorouracil in an animal model.
Topics: Animals; Cyclophosphamide; Drug Interactions; Female; Fluorouracil; Metabolic Clearance Rate; Methotrexate; Rats | 1987 |
Multiple drug intensification after cyclophosphamide, doxorubicin, and 5-fluorouracil (CAF) induction in metastatic breast cancer: a Southeastern Cancer Study Group phase II trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prednisone; Vincristine | 1987 |
Preoperative chemotherapy for fungating breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Methotrexate; Prednisone; Premedication | 1987 |
Sequential methotrexate/5-FU: FdUMP formation and TS inhibition in a transplantable rodent colon adenocarcinoma.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Deoxyuracil Nucleotides; Drug Interactions; Female; Fluorodeoxyuridylate; Fluorouracil; Kinetics; Male; Methotrexate; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Thymidylate Synthase | 1986 |
Methotrexate and 5-fluorouracil in the treatment of squamous and other carcinomas of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Synergism; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis | 1986 |
Chemosensitivity of human head and neck cancer xenografts in the clonogenic assay and in nude mice.
Topics: Animals; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; In Vitro Techniques; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Rats; Tumor Stem Cell Assay | 1986 |
[Comparison of in vitro assays for the cytotoxic effect of anticancer drugs].
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Count; Cell Line; Colony-Forming Units Assay; Diterpenes; Dose-Response Relationship, Drug; Esophageal Neoplasms; Fluorouracil; Humans; Methotrexate; Mitotic Index; Stomach Neoplasms; Tumor Stem Cell Assay | 1986 |
[Chemotherapy of recurrent squamous cell carcinomas in the ENT area with cisplatin/adriamycin (DDP/ADM) and methotrexate/5-fluorouracil (MTX/5-Flu): a retrospective comparison of 2 protocols].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Otorhinolaryngologic Neoplasms; Retrospective Studies | 1986 |
[Effect of methotrexate on 5-fluorouracil metabolism and clinical studies with methotrexate and 5-fluorouracil sequential therapy].
Topics: Drug Administration Schedule; Drug Synergism; Fluorouracil; Humans; Methotrexate; Neoplasms | 1986 |
Modulation of high-dose methotrexate toxicity by a non-toxic level of 5-fluorouracil.
Topics: Animals; Body Weight; Erythrocyte Count; Fluorouracil; Hematocrit; Hemoglobins; Leukocyte Count; Leukopenia; Male; Methotrexate; Mice; Platelet Count; Time Factors | 1986 |
Mitoxantrone, methotrexate, and 5-fluorouracil combination chemotherapy as first-line treatment in stage IV breast cancer.
Topics: Anthraquinones; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Staging | 1986 |
Hypothalamic-pituitary-ovarian axis in women with operable breast cancer treated with adjuvant CMF and tamoxifen.
Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Hypothalamo-Hypophyseal System; Mastectomy; Menopause; Methotrexate; Middle Aged; Ovarian Function Tests; Ovary; Pituitary Function Tests; Tamoxifen; Time Factors | 1986 |
[Compliance in adjuvant chemotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Patient Compliance; Tamoxifen | 1986 |
[Free serum amino acids for monitoring the therapy of female patients with breast cancer].
Topics: Amino Acids; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Monitoring, Physiologic; Prognosis | 1986 |
The influence of hormone receptors and hormonal adjuvant therapy on disease-free survival in breast cancer: a multifactorial analysis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Time Factors | 1986 |
Physical and psychologic distress associated with adjuvant chemotherapy in women with breast cancer.
Topics: Activities of Daily Living; Adult; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Postoperative Care; Prednisone; Psychiatric Status Rating Scales; Sexual Behavior; Stress, Psychological; Time Factors; Vincristine | 1986 |
High-dose metoclopramide and dexamethasone as an antiemetic in chemotherapy of breast cancer.
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Metoclopramide | 1986 |
Chemotherapy induces regression of brain metastases in breast carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Autopsy; Brain Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neurologic Examination; Prednisone; Progesterone; Vinblastine; Vincristine | 1986 |
The problem of local control in patients with advance breast cancer--a combined modality approach.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone | 1986 |
Salvage treatment of patients suffering relapse after adjuvant CMF chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Neoplasm Recurrence, Local; Ovariectomy; Retrospective Studies; Tamoxifen | 1986 |
Pharmacokinetic interactions of cyclophosphamide and 5-fluorouracil with methotrexate in an animal model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Specimen Collection; Cyclophosphamide; Drug Interactions; Female; Fluorouracil; Half-Life; Kinetics; Methotrexate; Neoplasms, Experimental; Rats; Statistics as Topic | 1986 |
[Adjuvant therapy of breast cancer. 1: Cytostatic therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate | 1986 |
[Sequential dose of methotrexate and 5-fluorouracil in advanced gastric cancer--response, survival time and toxicity].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 1986 |
Chemotherapy in invasive thymomas: five case reports.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dacarbazine; Doxorubicin; Female; Fluorouracil; Humans; Infant; Male; Methotrexate; Middle Aged; Prednisone; Thymoma; Thymus Neoplasms; Vincristine | 1986 |
Sequential methotrexate, 5-fluorouracil (high-dose), and doxorubicin for advanced gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 1986 |
Clinical pharmacology and cancer chemotherapy: an evolving interface?
Topics: Administration, Oral; Allopurinol; Antineoplastic Agents; Biological Availability; Chemotherapy, Cancer, Regional Perfusion; Drug Evaluation; Fluorouracil; Humans; Infusions, Intravenous; Kinetics; Melphalan; Mercaptopurine; Methotrexate; Pharmaceutical Vehicles | 1986 |
Assessment of adjuvant trials in breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Evaluation Studies as Topic; Female; Fluorouracil; Follow-Up Studies; Humans; International Cooperation; Lymph Nodes; Methotrexate; Middle Aged; Prednisone; Prognosis; Tamoxifen | 1986 |
Cell kinetics in selection and stratification of patients for adjuvant therapy of breast carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Carcinoma in Situ; Cell Cycle; DNA, Neoplasm; Epithelium; Evaluation Studies as Topic; Female; Flow Cytometry; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasm Invasiveness; Neoplasm Staging; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Thymidine; Tritium | 1986 |
Prognostic and therapeutic significance of pathological features of breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Female; Fluorouracil; Humans; Lymph Nodes; Mastectomy; Melphalan; Methotrexate; Middle Aged; Prognosis | 1986 |
[Combination of aminoglutethimide and polychemotherapy for the treatment of predominant bone metastasis in breast cancer].
Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Vinblastine; Vincristine | 1986 |
[Combined chemotherapy in metastatic breast cancer: predictive value of dose levels and performance status].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Probability | 1986 |
Primary chemotherapy in the treatment of inflammatory breast carcinoma: a study of 230 cases from the Institut Gustave-Roussy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; France; Humans; Inflammation; Methotrexate; Vincristine | 1986 |
An EORTC Gastrointestinal Group evaluation of the combination of sequential methotrexate and 5-fluorouracil, combined with adriamycin in advanced measurable gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 1986 |
[4-component chemotherapy and radiation therapy of breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Radiotherapy Dosage; Time Factors | 1986 |
Adriamycin, vinblastine and mitomycin C as second-line chemotherapy in advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Prednisone; Vinblastine; Vincristine | 1986 |
A reappraisal of oophorectomy in carcinoma of the breast.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Ovariectomy; Prognosis; Receptors, Estrogen; Time Factors | 1987 |
[Preoperative thermoradio- and thermochemotherapy of breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Preoperative Care; Radiotherapy Dosage; Time Factors; Vincristine | 1987 |
[Evaluation of the effectiveness of preoperative local thermoradio- and thermochemotherapy of breast cancer using thermography].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Hyperthermia, Induced; Methotrexate; Preoperative Care; Radiotherapy Dosage; Thermography; Time Factors; Vincristine | 1987 |
On the relevance of "second-line" cytotoxic chemotherapy in patients with metastatic breast cancer resistant to standard combinations.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Staging; Prednisone; Prognosis; Vincristine | 1986 |
[Rare late metastasis of a successfully treated advanced ovarian cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Cyclophosphamide; Cystadenocarcinoma; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms; Vinblastine | 1986 |
Influence of low-dose beta-interferon on natural killer cell activity in breast cancer patients subjected to chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line; Cyclophosphamide; Cytotoxicity, Immunologic; Female; Fluorouracil; Humans; Interferon Type I; Killer Cells, Natural; Male; Methotrexate; Reference Values | 1987 |
Toxicity of 5-fluorouracil for aerobic and hypoxic cells in two murine tumours.
Topics: Aerobiosis; Animals; Combined Modality Therapy; Fluorouracil; Lung Neoplasms; Mammary Neoplasms, Experimental; Methotrexate; Mice; Oxygen; Sarcoma, Experimental | 1987 |
[Clinical application of sequential dose methotrexate and 5-FU as a neoadjuvant chemotherapy in advanced stomach carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 1986 |
Adjuvant chemotherapy in males with cancer of the breast.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging | 1987 |
Metabolic efficiency of the liver in patients with breast cancer as determined by pharmacokinetics of phenazone.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Antipyrine; Biotransformation; Breast Neoplasms; Carcinoma; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Liver; Metabolic Clearance Rate; Methotrexate; Middle Aged | 1987 |
Megestrol acetate therapy for advanced breast cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Male; Megestrol; Megestrol Acetate; Menopause; Methotrexate; Receptors, Estrogen; Receptors, Progesterone | 1985 |
Quality of life measurement in breast cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Attitude to Health; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Prospective Studies; Quality of Life | 1985 |
[Complex treatment of stage II-III breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Neoplasm Staging; Postoperative Care; Radiotherapy Dosage | 1985 |
Case 6-1985: progressive pneumonitis after chemotherapy for breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Pneumonia; Prednisone; Vincristine | 1985 |
Use of tamoxifen in breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Tamoxifen | 1985 |
Chemohormonal therapy and endocrine function in breast cancer patients.
Topics: Adult; Amenorrhea; Androgens; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Estrogens; Female; Fluorouracil; Hormones; Humans; Menopause; Methotrexate; Pituitary Hormones; Prednisone; Prolactin; Tamoxifen; Vincristine | 1985 |
Combined cryosurgical, chemotherapeutic, and radiotherapeutic management of T1-4N0M0 oral cavity cancers.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Combined Modality Therapy; Cryosurgery; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neck Dissection; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Radioisotope Teletherapy | 1985 |
Weight gain in patients receiving adjuvant chemotherapy for carcinoma of the breast.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Receptors, Estrogen; Vincristine | 1985 |
The use of adjuvant chemotherapy for breast cancer in a community practice.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Private Practice; Vincristine | 1985 |
[Adjuvant chemo-hormonal therapy of breast cancer. New results on mortality].
Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Tamoxifen | 1985 |
[Reduction of vital capacity by combined adjuvant chemotherapy (CMF) for breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lung Volume Measurements; Methotrexate; Respiration; Vital Capacity | 1985 |
[Reduced-dose adjuvant CMF-chemotherapy combined with postoperative irradiation in breast cancer with lymphatic metastases. A prospective study of 45 patients].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cesium Radioisotopes; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Prognosis; Prospective Studies | 1985 |
Ten-year experience with CMF-based adjuvant chemotherapy in resectable breast cancer.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Leukopenia; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Prognosis; Receptors, Estrogen; Retrospective Studies; Tamoxifen | 1985 |
Effect of adjuvant tamoxifen and CMF on endocrine function of patients with operable breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Hormones; Humans; Menopause; Methotrexate; Middle Aged; Tamoxifen | 1985 |
Our experience regarding precautional chemotherapy in breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis | 1985 |
[Radiotherapy of carcinoma of the breast].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Fluorouracil; Humans; Mastectomy; Methotrexate; Neoplasm Staging | 1985 |
[Radio-chemotherapy integration].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate | 1985 |
Perioperative and conventionally timed chemotherapy in operable breast cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged | 1985 |
Preoperative adjuvant chemotherapy (neoadjuvant) for carcinoma of the breast: rationale and safety report.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Breast Neoplasms; Cell Division; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Pilot Projects; Time Factors | 1985 |
[Cardiotoxic effect of cytostatics in patients with breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Fluorouracil; Heart; Humans; Male; Methotrexate; Middle Aged; Myocardial Contraction; Prednisone; Vincristine | 1985 |
Adjuvant CMF chemotherapy in operable breast cancer: ten years later.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Methotrexate | 1985 |
[Cytostatic polychemotherapy in the aged].
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Fluorouracil; Humans; Lymphoma; Male; Melphalan; Methotrexate; Middle Aged; Multiple Myeloma; Prednisolone; Prednisone; Procarbazine; Risk; Vincristine | 1985 |
Surgical treatment of carcinoma of the breast. V. Changes in patient population and therapeutic modalities at a metropolitan hospital (1971-1980).
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; California; Cyclophosphamide; Ethnicity; Female; Fluorouracil; Hispanic or Latino; Hospitals, Urban; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Prognosis; Retrospective Studies; Urban Population | 1985 |
Tastes associated with parenteral chemotherapy for breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Infusions, Parenteral; Methotrexate; Middle Aged; Nausea; Retrospective Studies; Taste; Vomiting | 1985 |
Rationale for combining chemotherapy and hormonal therapy in breast cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Diethylstilbestrol; Drug Therapy, Combination; Estrogen Antagonists; Female; Fluorouracil; Humans; Interphase; Menopause; Methotrexate; Ovariectomy; Prednisone; Tamoxifen; Vincristine | 1985 |
[Chemotherapy of metastasizing breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prognosis; Vincristine | 1985 |
Management of inflammatory carcinoma of the breast. A combined modality approach.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Radiotherapy Dosage | 1985 |
Adjuvant chemotherapy with cyclophosphamide methotrexate and 5-fluorouracil (CMF) in stage II breast cancer in Indian patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; India; Methotrexate; Neoplasm Staging | 1985 |
[Drug administration in combination for management of cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Synergism; Fluorouracil; Humans; Mercaptopurine; Methotrexate; Neoplasms; Nimustine; Nitrosourea Compounds | 1985 |
The effects of cyclophosphamide, ketoconazole, aclacinomycin-A, methotrexate, and scheduled methotrexate-5-fluorouracil combination chemotherapy on the transplantable R-3327 prostatic adenocarcinoma in the F1 hybrid male rat.
Topics: Aclarubicin; Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Ketoconazole; Male; Methotrexate; Naphthacenes; Neoplasm Transplantation; Prostatic Neoplasms; Rats | 1985 |
Carcinoma of the tongue and floor of the mouth. Preliminary results of a multidisciplinary approach.
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Cryosurgery; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Mouth Floor; Mouth Neoplasms; Neoplasm Recurrence, Local; Tongue Neoplasms | 1985 |
[Therapy of recurrent squamous cell cancers in the ENT area with the sequential methotrexate (MTX)/5-fluorouracil (5-Fu) protocol].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Leucovorin; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Otorhinolaryngologic Neoplasms; Prognosis | 1985 |
[Sensitivity of the process of the formation of antigen-induced B-suppressors to DNA synthesis inhibitors].
Topics: Animals; Antibody-Producing Cells; Antimetabolites; B-Lymphocytes; Cytarabine; DNA; Erythrocytes; Fluorouracil; Immune Tolerance; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Spleen | 1985 |
Cancer chemotherapy: past is prologue.
Topics: 6-Aminonicotinamide; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Female; Fluorouracil; Humans; Male; Mammary Neoplasms, Experimental; Methotrexate; Methylthioinosine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Phosphonoacetic Acid | 1985 |
Combination chemotherapy of breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Prednisone; Vincristine | 1985 |
Maintenance chemotherapy for high-risk patients. A preliminary report.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Patient Compliance; Prospective Studies; Risk; Sex Ratio | 1985 |
Lack of enhanced cytotoxicity of cultured L1210 cells using folinic acid in combination with sequential methotrexate and fluorouracil.
Topics: Animals; Cell Survival; DNA Replication; Drug Interactions; Fluorouracil; Kinetics; Leucovorin; Leukemia L1210; Methotrexate; Mice; Thymidylate Synthase; Transcription, Genetic | 1985 |
The cyclophosphamide, hexamethylmelamine, 5 fluorouracil (CHF) regimen in the treatment of advanced and recurrent ovarian cancer.
Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Hysterectomy; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Reoperation | 1985 |
[Effects of combination chemotherapy of MCNU with various anti-cancer agents].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Fluorouracil; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Mice, Inbred DBA; Mitomycin; Mitomycins; Nitrosourea Compounds; Thioguanine | 1985 |
Functional and structural changes of the human proximal small intestine after cytotoxic therapy.
Topics: Adult; alpha-Glucosidases; beta-Galactosidase; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Intestinal Absorption; Jejunum; Methotrexate; Microvilli; Middle Aged; Sucrase | 1985 |
[In vivo antitumor activity of hydrosoluble derivatives of 7-hydroxycholesterols].
Topics: Animals; Antineoplastic Agents; Carcinoma, Krebs 2; Cyclophosphamide; Female; Fluorouracil; Hydroxycholesterols; Methotrexate; Mice | 1985 |
[Preoperative cancer chemotherapy for gastric cancer].
Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Parenteral; Lymphatic Metastasis; Methotrexate; Mitomycin; Mitomycins; Picibanil; Preoperative Care; Stomach Neoplasms | 1985 |
Intraperitoneal chemotherapy for advanced ovarian cancer.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms; Peritoneal Cavity; Thiosulfates | 1985 |
Six-drug chemotherapy (hexamethylmelamine, doxorubicin, cisplatin, cyclophosphamide, methotrexate, and 5-FU; CHAMP-5) for ovarian carcinoma: alternating sequences of combination regimens.
Topics: Adenocarcinoma; Age Factors; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms | 1985 |
[Human tumor clonogenic assay in human breast cancer].
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cells, Cultured; Colony-Forming Units Assay; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance; Fluorouracil; Humans; Methotrexate; Mitomycin; Mitomycins; Tumor Stem Cell Assay; Vincristine | 1985 |
Hexamethylmelamine, methotrexate and 5-fluorouracil (HMF) for progressive ovarian carcinoma during therapy with cis-platinum, cyclophosphamide +/- doxorubicin.
Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Resistance; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms; Reoperation | 1985 |
Potentiation by vitamin A of the action of anticancer agents against murine tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Diterpenes; Doxorubicin; Drug Evaluation, Preclinical; Drug Synergism; Fluorouracil; Leukemia P388; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds; Retinyl Esters; Sarcoma 180; Vitamin A | 1985 |
[A case of long-term survival of liver metastasis of breast cancer successfully treated with chemotherapy and endocrine therapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Liver; Liver Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Methotrexate; Middle Aged; Tamoxifen; Tegafur | 1985 |
[Adjuvant mono- and polychemotherapy in breast cancer (a randomized study)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Staging; Postoperative Care; Radiotherapy; Random Allocation; Thiotepa; Time Factors | 1985 |
Sequential therapy with methotrexate and 5-fluorouracil in the treatment of advanced colorectal carcinoma.
Topics: Adult; Aged; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Rectal Neoplasms | 1986 |
The increased cytotoxicity in colon adenocarcinoma of methotrexate-5-fluorouracil is not associated with increased induction of lesions in DNA by 5-fluorouracil.
Topics: Adenocarcinoma; Cell Division; Cell Survival; Cells, Cultured; Colonic Neoplasms; DNA, Neoplasm; Drug Administration Schedule; Drug Interactions; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; Methotrexate | 1986 |
[Criteria for evaluating the efficacy of treatment of breast cancer metastases to the bones].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Methotrexate; Middle Aged | 1986 |
Combined cytotoxic and endocrine treatment of postmenopausal patients with advanced breast cancer: preliminary results of a phase II study of the combination of prednimustine, novantrone, methotrexate, 5-fluorouracil, and tamoxifen.
Topics: Adult; Aged; Alopecia; Anthraquinones; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Mitoxantrone; Prednimustine; Tamoxifen | 1986 |
[Treatment of metastasized breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Prednisolone; Prognosis; Vincristine | 1986 |
Methyl-CCNU and methotrexate therapy in patients with advanced colorectal cancer after failure of 5-fluorouracil chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Nitrosourea Compounds; Rectal Neoplasms; Semustine | 1986 |
Phase II study of sequential methotrexate and 5-FU combination in the treatment of advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Fluorouracil; Humans; Methotrexate; Middle Aged; Rectal Neoplasms | 1986 |
Modulated chemo-hormonotherapy in advanced breast cancer. A pilot study.
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Female; Fluorouracil; Hormones; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prospective Studies; Tamoxifen | 1986 |
Treatment of persistent or recurrent ovarian carcinoma with sequential methotrexate and 5-fluorouracil.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms | 1986 |
[Therapeutic effect of sequential doses of methotrexate (MTX) and 5-fluorouracil (5-FU) in advanced gastric cancer: comparison of intermediate-dose MTX with high-dose MTX].
Topics: Adult; Aged; Alopecia; Diarrhea; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Platelet Count; Stomach Neoplasms; Vomiting | 1985 |
Effects of 5-fluorouracil on dihydrofolate reductase and dihydrofolate reductase mRNA from methotrexate-resistant KB cells.
Topics: Animals; Drug Resistance; Fluorometry; Fluorouracil; Gene Amplification; KB Cells; Methotrexate; RNA, Messenger; Tetrahydrofolate Dehydrogenase | 1985 |
Acute renal failure and death following sequential intermediate-dose methotrexate and 5-FU: a possible adverse effect due to concomitant indomethacin administration.
Topics: Acute Kidney Injury; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Interactions; Fluorouracil; Humans; Indomethacin; Liver Neoplasms; Male; Methotrexate; Middle Aged | 1985 |
[Chemotherapy protocol for metastasizing colorectal carcinoma. Methotrexate, 5-fluorouracil and cytarabine].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Cytarabine; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms | 1985 |
[Biochemical modulation in cancer chemotherapy].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Synergism; Fluorouracil; Humans; Leukemia L1210; Methotrexate; Mice; Neoplasms; Nucleosides; Pyrimidine Nucleosides | 1985 |
Sequential methotrexate and 5-fluorouracil in the primary treatment of metastatic colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Rectal Neoplasms; Time Factors | 1985 |
The effect of a susceptibility to motion sickness on the side effects of cancer chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease Susceptibility; Epidemiologic Methods; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Motion Sickness; Nausea | 1985 |
Local-regional failure in patients treated with adjuvant chemotherapy for breast cancer.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies | 1985 |
[Chemotherapy for recurrent breast carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Recurrence, Local; Prednisone; Vincristine | 1985 |
Sequential infusions of methotrexate and 5-fluorouracil in advanced cancer: pharmacology, toxicity, and response.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Half-Life; Humans; Male; Methotrexate; Middle Aged; Neoplasms | 1985 |
Clonogenic response of cells of murine intestinal crypts to 12 cytotoxic drugs.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Survival; Clone Cells; Dose-Response Relationship, Drug; Fluorouracil; Hydroxyurea; Intestinal Mucosa; Male; Methotrexate; Mice; Mice, Inbred Strains; Vincristine | 1985 |
Sequential methotrexate and 5-fluorouracil in the treatment of non-small cell carcinoma of the lung.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Evaluation; Fluorouracil; Humans; Lung Neoplasms; Methotrexate | 1985 |
Treatment of diffuse aggressive non-Hodgkin's lymphomas with an intensive multi-drug regimen including high-dose cytosine arabinoside (F-MACHOP).
Topics: Adolescent; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Fluorouracil; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Prognosis; Recurrence; Vincristine | 1985 |
Weight gain during adjuvant chemotherapy for breast cancer.
Topics: Adult; Aged; Body Weight; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Prognosis; Risk | 1985 |
Neoadjuvant (preoperative) chemotherapy for breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Breast Neoplasms; Cell Division; Combined Modality Therapy; Cyclophosphamide; Drug Resistance; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Kinetics; Methotrexate; Middle Aged; Pilot Projects; Premedication | 1985 |
A phase II study of sequential methotrexate and fluorouracil in advanced colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Colonic Neoplasms; Drug Evaluation; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Rectal Neoplasms | 1985 |
The effect of methotrexate pretreatment on 5-fluorouracil kinetics in sarcoma 180 in vivo.
Topics: Animals; Drug Administration Schedule; Female; Fluorouracil; Kinetics; Methotrexate; Mice; RNA, Neoplasm; Sarcoma 180; Thymidylate Synthase | 1985 |
Chemotherapy before radiotherapy for T3 bladder cancer. A pilot study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Pilot Projects; Prognosis; Urinary Bladder Neoplasms | 1985 |
Factors affecting growth and drug sensitivity of mouse mammary tumor lines in collagen gel cultures.
Topics: Animals; Cells, Cultured; Collagen; Colony-Forming Units Assay; DNA, Neoplasm; Female; Fluorouracil; Gels; Mammary Neoplasms, Experimental; Melphalan; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Tumor Stem Cell Assay | 1985 |
Polychemotherapeutic treatment for ovarian carcinoma (our experience).
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms; Prognosis | 1985 |
5-Fluorouracil and methotrexate administered simultaneously as a continuous infusion. A phase I study.
Topics: Adult; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Neoplasms; Stomatitis; Thrombocytopenia | 1985 |
The clinical setting and pharmacology of intraperitoneal chemotherapy: an overview.
Topics: Antineoplastic Agents; Catheters, Indwelling; Cisplatin; Female; Fluorouracil; Humans; Infusions, Parenteral; Kinetics; Methotrexate; Ovarian Neoplasms; Peritoneal Cavity | 1985 |
[Effects of combination chemotherapy M-VEMFH including mitoxantrone in advanced breast cancer].
Topics: Adult; Aged; Anthraquinones; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Prednisolone; Vincristine | 1985 |
[Duration of remission in advanced gastric cancer patients responding to sequential dose of MTX and 5-FU].
Topics: Administration, Oral; Adult; Aged; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Stomach Neoplasms; Suppositories | 1985 |
Sequential methotrexate (MTX) and 5-fluorouracil (FU) in human tumor xenografts.
Topics: Animals; Carcinoma 256, Walker; Carcinoma, Squamous Cell; Cell Line; Dose-Response Relationship, Drug; Drug Administration Schedule; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Time Factors | 1985 |
Combined chemotherapy, cryosurgery, and radiotherapy/surgery for oral cancer.
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Cryosurgery; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Methotrexate; Mouth Neoplasms; Time Factors | 1985 |
[Use of antimetabolites in treating callous perforating stomach ulcers].
Topics: Antimetabolites, Antineoplastic; Callosities; Female; Fluorouracil; Humans; Injections, Intralymphatic; Male; Methotrexate; Middle Aged; Peptic Ulcer Perforation; Stomach Ulcer | 1985 |
Timing- and sequence-dependent synergism between etoposide and methotrexate or etoposide, methotrexate and 5-fluorouracil in advanced leukemia L1210.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Etoposide; Female; Fluorouracil; Leukemia L1210; Methotrexate; Mice; Mice, Inbred Strains; Podophyllotoxin; Time Factors | 1985 |
Effects of anticancer drugs on folate disposition and excretion.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Folic Acid; Liver; Lung Neoplasms; Male; Methotrexate; Mice | 1985 |
Acceleration of casein induced amyloidosis in mice by immunosuppressive agents.
Topics: Amyloid; Amyloidosis; Animals; Azathioprine; Busulfan; Caseins; Chloramphenicol; Cortisone; Dactinomycin; Daunorubicin; DNA; Female; Fluorouracil; Immunosuppressive Agents; Liver; Male; Mercaptopurine; Methotrexate; Mice; RNA; Spleen; Vinblastine | 1971 |
Systemic chemotherapy of mammary carcinoma.
Topics: Amines; Antineoplastic Agents; Azirines; Azo Compounds; Breast Neoplasms; Caproates; Carbohydrates; Chlorambucil; Cyclophosphamide; Evaluation Studies as Topic; Floxuridine; Fluorouracil; Humans; Imidazoles; Mercaptopurine; Methotrexate; Mitomycins; Palliative Care; Prednisone; Triazines; Vincristine | 1971 |
[Experiences in the palliative chemotherapy of 228 cases of unmeasurable and 52 measurable intrapulmonary tumors].
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Mitomycins; Neoplasm Metastasis; Palliative Care; Vinblastine | 1971 |
[Chemotherapy of so-called solid tumors].
Topics: Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Drug Synergism; Fluorouracil; Humans; Immunosuppressive Agents; Methotrexate; Neoplasms; Palliative Care; Prognosis; Thiotepa; Vinblastine | 1971 |
Chemotherapy of vesical and prostatic tumours.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Cobalt Isotopes; Cystitis; Daunorubicin; Ethoglucid; Fluorouracil; Humans; Hydroxyurea; Male; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Papilloma; Prostatic Neoplasms; Thiotepa; Urinary Bladder Neoplasms | 1971 |
[Chemotherapy by intra-arterial path in cancer of the "head and neck" region].
Topics: Antineoplastic Agents; Bleomycin; Facial Neoplasms; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Laryngeal Neoplasms; Lip Neoplasms; Maxillary Neoplasms; Methotrexate; Mouth Neoplasms; Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Salivary Gland Neoplasms; Thyroid Neoplasms; Tongue Neoplasms | 1971 |
Factors influencing the success of arterial infusion chemotherapy for cancer of the head and neck.
Topics: Age Factors; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cystadenoma; Drug Synergism; Eye Neoplasms; Female; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Laryngeal Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasms; Pharyngeal Neoplasms; Remission, Spontaneous; Skin Neoplasms | 1972 |
Intra-arterial infusion--an adjuvant to the treatment of oral carcinoma.
Topics: Adult; Aged; Carotid Artery, External; Catheterization; Evaluation Studies as Topic; Floxuridine; Fluorouracil; Gingival Neoplasms; Humans; Injections, Intra-Arterial; Leucovorin; Lip Neoplasms; Methotrexate; Middle Aged; Mouth Neoplasms; Palatal Neoplasms; Palliative Care | 1972 |
[Mitomycin alone and in therapeutic association in the palliative treatment of solid tumors].
Topics: Antineoplastic Agents; Breast Neoplasms; Cobalt Isotopes; Cyclophosphamide; Drug Combinations; Female; Fluorouracil; Humans; Intestinal Neoplasms; Laryngeal Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Melanoma; Methotrexate; Mitomycins; Neoplasms; Palliative Care; Pharyngeal Neoplasms; Sarcoma; Thiotepa; Tongue Neoplasms; Urogenital Neoplasms; Vinblastine | 1971 |
[Intermittent polychemotherapy in inoperable bronchial cancer].
Topics: Aged; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Humans; Life Expectancy; Male; Methotrexate; Middle Aged; Palliative Care; Prognosis; Time Factors; Vinblastine | 1972 |
Serum alpha-fetoprotein as a biochemical marker for hepatocellular carcinoma.
Topics: Adolescent; Adult; Age Factors; Alpha-Globulins; Blood Transfusion; Carcinoma, Hepatocellular; Female; Fetal Proteins; Fluorouracil; Hepatectomy; Humans; Immunodiffusion; Liver Neoplasms; Male; Methotrexate; Middle Aged; Nitrosourea Compounds; Sex Factors; Time Factors | 1972 |
The enhanced therapeutic effect of cis-platinum (II) diamminodichloride against L1210 leukemia when combined with cyclophosphamide or 1,2-bis(3,5-dioxopiperazine-1-yl)propane or several other antitumor agents.
Topics: Amines; Animals; Antineoplastic Agents; Azacitidine; Camptothecin; Carmustine; Chlorides; Cyclophosphamide; Cytarabine; Drug Synergism; Emetine; Fluorouracil; Ketones; Leukemia L1210; Male; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Piperazines; Platinum; Propane; Time Factors | 1973 |
[Therapy of bronchial carcinoma. Intermittent high-dosage polychemotherapy of bronchial carcinoma in combination with radical surgery for the prevention of recurrences and in primarily inoperable patients].
Topics: Adult; Aged; Antineoplastic Agents; Austria; Bronchial Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Palliative Care | 1973 |
Cancer of the tongue.
Topics: Bleomycin; Carcinoma, Squamous Cell; Dental Caries; Electrocoagulation; Fluorides, Topical; Fluorouracil; Glossectomy; Humans; Lymphatic Metastasis; Methotrexate; Neck Dissection; Neoplasm Metastasis; Neoplasm Recurrence, Local; Preoperative Care; Radiotherapy Dosage; Tongue Neoplasms | 1973 |
Chemotherapy and hormone therapy in gynecologic cancer.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Choriocarcinoma; Dactinomycin; Female; Fluorouracil; Hormones; Humans; Hydatidiform Mole; Methotrexate; Ovarian Neoplasms; Palliative Care; Pregnancy; Progesterone; Prognosis; Uterine Cervical Neoplasms; Uterine Neoplasms | 1973 |
Value of cytotoxic infusion in dyspnoea and dysphagia due to cancer.
Topics: Antineoplastic Agents; Cyclophosphamide; Deglutition Disorders; Dyspnea; Esophageal Neoplasms; Fluorouracil; Humans; Infusions, Parenteral; Laryngeal Neoplasms; Methotrexate; Neoplasms; Pharyngeal Neoplasms | 1973 |
Chemotherapy of lung cancer: the experience of the National Cancer Institute of Milan.
Topics: Adenocarcinoma; Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Doxorubicin; Fluorouracil; Humans; Hydroxyurea; Italy; Lung Neoplasms; Methotrexate; Procarbazine; Remission, Spontaneous | 1973 |
Chemotherapeutic response of epithelial tumors produced by primary implantation of a nonproducer line of murine sarcoma virus-transformed BALB 3T3 cells.
Topics: Animals; Bleomycin; Cyclophosphamide; Female; Fluorouracil; Male; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms; Nitrosourea Compounds; Sarcoma, Experimental; Time Factors; Transplantation, Homologous | 1973 |
[Intra-arterial chemotherapy of head and neck tumors: statistical study of 129 cases treated at the Institut Gustave Roussy].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Facial Neoplasms; Fluorouracil; Head and Neck Neoplasms; Humans; Imidazoles; Jaw Neoplasms; Mannomustine; Melanoma; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Recurrence, Local; Pharyngeal Neoplasms; Prognosis; Sarcoma; Thiotepa; Vinblastine | 1973 |
[Selective tumour chemotherapy using oncobiograms (author's transl)].
Topics: Animals; Antineoplastic Agents; Bleomycin; Cricetinae; Culture Techniques; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Evaluation; Drug Resistance; Fluorouracil; Humans; Methods; Methotrexate; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Procarbazine; Radioisotopes; Rats; Scintillation Counting; Thymidine; Triaziquone; Uridine | 1974 |
Intra-arterial infusion chemotherapy in head and neck cancer. A clinical and experimental study.
Topics: Animals; Carotid Artery, External; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Disease Models, Animal; Drug Therapy, Combination; Fluorouracil; Follow-Up Studies; Head; Head and Neck Neoplasms; Humans; Methods; Methotrexate; Neoplasms; Rats; Rhabdomyosarcoma; Staining and Labeling | 1973 |
Chemotherapy in recurrent heat and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Injections, Intra-Arterial; Injections, Intramuscular; Methotrexate; Neoplasm Recurrence, Local; Neoplasms; Vinblastine; Vincristine | 1974 |
Potentially useful combinations of chemotherapy detected in mouse tumor systems.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Azauridine; Bleomycin; Camptothecin; Cyclic P-Oxides; Cyclophosphamide; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethylamines; Fluorouracil; Imidazoles; Leukemia L1210; Lung Neoplasms; Methotrexate; Mice; Neoplasms, Experimental; Oxazines; Piperazines; Procarbazine; Propane; Triazenes | 1974 |
Influence of cytostatics on aggregation and adenine nucleotides of platelets.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Amidines; Antineoplastic Agents; Aspirin; Bleomycin; Blood Platelets; Cell Membrane; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Glyoxal; Humans; Hydrazones; Methotrexate; Neoplasms; Platelet Adhesiveness; Triaziquone; Vinca Alkaloids | 1972 |
[Antimetabolites in the treatment of acute human leukoses. Mechanism of action and conditioning factors in the cellular response to drugs. II].
Topics: Antimetabolites; Azacitidine; Azaguanine; Azauridine; Cell Membrane Permeability; Cytarabine; DNA, Neoplasm; Fluorouracil; Humans; Immunity, Cellular; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Purines; Pyrimidines | 1974 |
Metastatic basal cell carcinoma: review, report of a case, and chemotherapy.
Topics: Aged; Antineoplastic Agents; Biopsy, Needle; Bleomycin; Carcinoma, Basal Cell; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Neoplasm Metastasis; Thigh | 1974 |
[Indication and achievements of after-care examinations of urologic tumors. Chemotherapeutic report].
Topics: Aftercare; Antineoplastic Agents; Bleomycin; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Mitomycins; Plicamycin; Postoperative Complications; Procarbazine; Urogenital Neoplasms; Vinblastine | 1973 |
[The effects of cytostatic agents on short-term cultures (3H-uridine incorporation) and tissue cultures (cell counts) from human tumors (author's transl)].
Topics: Antineoplastic Agents; Bleomycin; Cell Count; Cell Transformation, Neoplastic; Cells, Cultured; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; In Vitro Techniques; Methods; Methotrexate; Neoplasms; Ovarian Neoplasms; Podophyllin; Suspensions; Time Factors; Triaziquone; Tritium; Uridine | 1974 |
[Comparison of several different methods of antiblastic therapy in advanced carcinomas of the digestive system].
Topics: Antineoplastic Agents; Bleomycin; Cyclophosphamide; Drug Therapy, Combination; Esophageal Neoplasms; Fluorouracil; Gallbladder Neoplasms; Gastrointestinal Neoplasms; Humans; Methotrexate; Pancreatic Neoplasms; Vincristine | 1974 |
Experimental chemotherapy in carcinoma of the cervix.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Uterine Cervical Neoplasms; Vincristine | 1974 |
[Palliative chemotherapy of bronchial cancers. Current status of the problem].
Topics: Antineoplastic Agents; Bleomycin; Bronchial Neoplasms; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Emetine; Fluorouracil; Humans; Hydroxyurea; Methotrexate; Mitomycins; Mustard Compounds; Palliative Care; Procarbazine; Thiotepa; Vinblastine | 1973 |
[Three years of experience in the polychemotherapy of inoperable bronchial carcinoma].
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adult; Aged; Antineoplastic Agents; Austria; Bronchial Neoplasms; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Long-Term Care; Male; Methotrexate; Middle Aged; Palliative Care; Time Factors; Vinblastine | 1974 |
Editorial: Drug targets in cancer chemotherapy.
Topics: Antineoplastic Agents; Dactinomycin; Doxorubicin; Enzyme Inhibitors; Fluorouracil; Isoenzymes; Methotrexate; Neoplasms; Rifampin | 1974 |
[The effect of cytostatic drugs on blood platelets and lymphocytes in patients with neoplasms].
Topics: Adenine Nucleotides; Adenosine Diphosphate; Amidines; Antibiotics, Antineoplastic; Bleomycin; Blood Platelets; Breast Neoplasms; Bronchial Neoplasms; Cyclophosphamide; Doxorubicin; Firefly Luciferin; Fluorouracil; Glyoxal; Hodgkin Disease; Humans; Hydrazones; Leukemia; Luciferases; Lymphocytes; Melphalan; Methotrexate; Neoplasms; Nephelometry and Turbidimetry; Plasmacytoma; Platelet Aggregation; Vinca Alkaloids | 1974 |
Prolonged intra-aortic infusion therapy with anti-tumor agents for advanced cancer of the stomach, colon and rectum.
Topics: Adult; Aged; Antineoplastic Agents; Aorta; Bleomycin; Catheterization; Colonic Neoplasms; Cytarabine; Doxorubicin; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Mitomycins; Rectal Neoplasms; Stomach Neoplasms; Time Factors | 1971 |
[1973 treatment of acute leukemias].
Topics: Chlorambucil; Colchicine; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Vinblastine; Vincristine | 1974 |
The roles of radiotherapy and cytotoxic drugs in the management of carcinoma of the esophagus.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Fluorouracil; Humans; Male; Methotrexate; Radiotherapy, High-Energy | 1973 |
The treatment of hepatic metastases by long-term chemotherapeutic infusions.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Colonic Neoplasms; Evaluation Studies as Topic; Female; Floxuridine; Fluorouracil; Humans; Infusions, Parenteral; Liver Neoplasms; Male; Methods; Methotrexate; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms | 1970 |
Some aspects of the use of cytostatic drugs in dermatology.
Topics: Colchicine; Dactinomycin; Fluorouracil; Humans; Melanoma; Methotrexate; Mycosis Fungoides; Nitrogen Mustard Compounds; Psoriasis; Sarcoma, Kaposi; Skin Neoplasms; Vinblastine | 1966 |
Uric acid excretion following pelvic perfusion for malignancy.
Topics: Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Humans; Melphalan; Methotrexate; Palliative Care; Pelvic Neoplasms; Tourniquets; Uric Acid | 1967 |
Continuous arterial infusion chemotherapy. Experience with 44 cases.
Topics: Adenocarcinoma; Arteries; Brain Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Catheterization; Chloramphenicol; Facial Neoplasms; Fever; Fluorouracil; Head and Neck Neoplasms; Humans; Infections; Infusions, Parenteral; Leucovorin; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Neoplasm Metastasis; Palliative Care; Penicillins; Stomach Neoplasms; Thoracic Neoplasms | 1967 |
Treatment of plantar warts with cytostatics.
Topics: Antineoplastic Agents; Fluorouracil; Gels; Humans; Methotrexate; Occlusive Dressings; Podophyllin; Vinblastine; Warts | 1967 |
Prevention of tuberculous cavity formation by immunosuppressive drugs.
Topics: Animals; Azathioprine; Cyclophosphamide; Dactinomycin; Fluorouracil; Immunosuppressive Agents; Mercaptopurine; Methotrexate; Rabbits; Tuberculosis, Pulmonary | 1968 |
Operation, external irradiation, radioactive isotopes, and chemotherapy in treatment of metastatic ovarian malignancies.
Topics: Ascites; Carcinoma; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Follow-Up Studies; Gold Colloid, Radioactive; Humans; Methotrexate; Neoplasm Metastasis; Ovarian Neoplasms; Palliative Care; Thiotepa | 1968 |
[Loco-regional and sequential chemotherapy of advanced cancer].
Topics: Adult; Carcinoma; Carcinoma, Hepatocellular; Chemotherapy, Cancer, Regional Perfusion; Dysgerminoma; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Palliative Care; Rectal Neoplasms; Testicular Neoplasms; Uterine Cervical Neoplasms; Vinblastine | 1968 |
Chemotherapy of induced skin tumors in mice.
Topics: Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Benz(a)Anthracenes; Busulfan; Carcinoma, Squamous Cell; Chlorambucil; Cortisone; Cyclophosphamide; Dactinomycin; Estradiol; Female; Fluorouracil; Hydroxyurea; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nitroso Compounds; Papilloma; Skin Neoplasms; Testosterone; Triethylenemelamine | 1968 |
[Method and results of experimental chemotherapy of a human colonic carcinoma (H.Ad.No. 1) in the cheek pouch of the golden hamster].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Aziridines; Cheek; Colonic Neoplasms; Cricetinae; Cyclophosphamide; Dactinomycin; Fluorouracil; Hydrazines; Methods; Methotrexate; Neoplasm Transplantation; Triaziquone | 1969 |
[Estimation of tumor sensitivity in vitro. I. Comparative studies with the Jensen sarcoma in vivo and in vitro after 1-hour-incubation].
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Autoradiography; Cycloparaffins; Dactinomycin; DNA, Neoplasm; Fluorouracil; In Vitro Techniques; Methods; Methotrexate; Mustard Compounds; Neoplasm Transplantation; Nucleosides; Rats; RNA, Neoplasm; Sarcoma, Experimental; Thymidine; Time Factors; Triaziquone; Tritium; Uridine; Vinblastine | 1969 |
[On the question of preclinical selection of cytostatics in the area of treatment of human tumors].
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Carcinoma 256, Walker; Cricetinae; Culture Techniques; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Fluorouracil; Humans; Lung Neoplasms; Methods; Methotrexate; Neoplasms; Neoplasms, Experimental; Radionuclide Imaging; Rats; RNA, Neoplasm; Stimulation, Chemical; Thymidine; Triaziquone; Tritium; Vinblastine; Vincristine | 1969 |
[Treatment of inoperable tumors by continuous and prolonged arterial perfusion of an antimitotic association].
Topics: Antineoplastic Agents; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Floxuridine; Fluorouracil; Humans; Methotrexate; Mitomycins; Neoplasms; Palliative Care; Perfusion; Vinblastine; Vincristine | 1969 |
Malignant hepatoma in the Bantu.
Topics: Adenoma, Bile Duct; Africa, Eastern; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Black People; Blood Proteins; Carcinoma, Hepatocellular; Clinical Enzyme Tests; Cyclophosphamide; Cytarabine; Dactinomycin; Fluorouracil; gamma-Globulins; Humans; Hydroxyurea; Liver Neoplasms; Male; Mercaptopurine; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Prednisone; Prognosis; South Africa; Vincristine | 1970 |
[Effect of inhibitors of nucleinic, protein synthesis and cell division on primary immunologic response].
Topics: Animals; Antibody Formation; Antibody-Producing Cells; Chloramphenicol; Colchicine; Depression, Chemical; DNA; Ethionine; Flavonoids; Fluorouracil; Methotrexate; Mice; RNA; Spleen | 1970 |
[Detection of a moderate staphylococcal phage by means of antineoplastic agents].
Topics: Aminopterin; Antibiotics, Antineoplastic; Anticholesteremic Agents; Antimetabolites; Antineoplastic Agents; Chlorambucil; Colchicine; Cyclophosphamide; Dactinomycin; Drug Resistance, Microbial; Flavonoids; Fluorouracil; Lysogeny; Mechlorethamine; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Olivomycins; Staphylococcus; Staphylococcus Phages; Thiotepa; Ultraviolet Rays; Uracil; Vinblastine; Vincristine | 1970 |
[FSH and steroid hormone excretion in breast cancer during chemotherapy].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Breast Neoplasms; Cyclophosphamide; Estrogens; Female; Fluorouracil; Follicle Stimulating Hormone; Glucocorticoids; Humans; Menopause; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pregnanediol; Thiotepa; Time Factors; Vinblastine | 1972 |
Chemotherapy for lung cancer at the Institute of Experimental and Clinical Oncology, Academy of Medical Sciences, USSR.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Fluorouracil; Humans; Imines; Lung Neoplasms; Mechlorethamine; Methotrexate; Moscow; Nitrosourea Compounds; Thiotepa; Time Factors; Vinblastine; Vincristine | 1973 |
A comparison of the three in vivo assays for haemopoietic stem cells.
Topics: Animals; Antibiotics, Antineoplastic; Bone Marrow Cells; Bone Marrow Examination; Bone Marrow Transplantation; Cell Differentiation; Cell Division; Cyclophosphamide; Erythrocytes; Femur; Fluorouracil; Hematopoietic Stem Cells; Leukocytes; Male; Methotrexate; Mice; Mice, Inbred C57BL; Nitrogen Mustard Compounds; Radiation Chimera; Spleen; Transplantation, Homologous; Vinblastine | 1973 |
Ascaridia galli: effects of immunosuppressive drugs or bursectomy in chickens.
Topics: Animals; Ascariasis; Ascaridia; Azauridine; Bursa of Fabricius; Chickens; Chlorambucil; Cortisone; Dactinomycin; Fludrocortisone; Fluorouracil; Glucocorticoids; Immunosuppressive Agents; Male; Mercaptopurine; Methotrexate; Poultry Diseases; Prednisolone; Prednisone; Statistics as Topic; Thioguanine; Thiotepa; Vincristine | 1974 |
[Chromosomal studies in correlation with other biologic constants in neoplasms treated by chemotherapy].
Topics: Adult; Antibody Formation; Bone Marrow; Cell Division; Chromosome Aberrations; Female; Fluorouracil; Humans; Immunity, Cellular; Male; Melphalan; Methotrexate; Middle Aged; Mitosis; Neoplasms; Thiotepa | 1974 |
The growth of human tumours in immunosuppressed mice and their response to chemotherapy.
Topics: Animals; Chlorambucil; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Immunosuppression Therapy; Male; Melphalan; Methotrexate; Mice; Mice, Inbred CBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Ovarian Neoplasms; Thiotepa; Thymectomy; Transplantation, Heterologous; Triaziquone; Urinary Bladder Neoplasms; Vinblastine; Vincristine | 1974 |
Breast cancer management.
Topics: Alabama; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Melphalan; Methotrexate; Middle Aged; Surveys and Questionnaires; Thiotepa | 1974 |
Interdisciplinary approach to advanced ovarian cancer.
Topics: Alkylating Agents; Ascites; Chlorambucil; Dactinomycin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Intestinal Fistula; Intestinal Obstruction; Medroxyprogesterone; Methotrexate; Ovarian Neoplasms; Patient Care Team; Phosphorus Radioisotopes; Progesterone; Radiotherapy Dosage; Thiotepa; Triaziquone; Vinblastine | 1974 |
Intraprostatic injections of various antitumoral compounds into rats.
Topics: Animals; Antineoplastic Agents; Dactinomycin; Ethylene Glycols; Fluorouracil; Injections; Male; Methotrexate; Microscopy, Electron; Mitomycins; Podophyllin; Prostate; Rats; Thiotepa | 1974 |
In vitro drug selection in antineoplastic chemotherapy.
Topics: Antineoplastic Agents; Biopsy; Cell Survival; Cells, Cultured; Cyclophosphamide; Cytological Techniques; Dactinomycin; Dose-Response Relationship, Drug; Drug Combinations; Fluorouracil; Humans; Methotrexate; Procarbazine; Thiotepa; Vinblastine; Vincristine | 1974 |
[Characteristics of growth and sensitivity to cytostatics of Walker 256 carcinosarcoma in randombred and Wistar rats].
Topics: Animals; Antineoplastic Agents; Aziridines; Carcinoma 256, Walker; Cyclophosphamide; Fluorouracil; Melphalan; Methotrexate; Nitrofurans; Nitrogen Mustard Compounds; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Species Specificity; Thiotepa | 1974 |
Inhibition of plaque formation by myxoma and fibroma viruses with pyrimidine analogues.
Topics: Antiviral Agents; Benzimidazoles; Bromodeoxyuridine; Culture Techniques; Cytosine; DNA, Viral; Fibroma; Floxuridine; Fluorouracil; Idoxuridine; Mercaptopurine; Methotrexate; Myxoma virus; Nucleosides; Oncogenic Viruses; Thiosemicarbazones; Thymine | 1965 |
Chemotherapy studies in an animal tumor spectrum. II. Sensitivity of tumors to fourteen antitumor chemicals.
Topics: Animals; Antineoplastic Agents; Arsenicals; Busulfan; Cyclophosphamide; Dactinomycin; Diethylstilbestrol; Floxuridine; Fluorouracil; Hydrocortisone; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Urethane; Vinblastine | 1966 |
Myeloid leukemia C-1498 as a screen for cancer chemotherapeutic agents.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Azaguanine; Azaserine; Busulfan; Cyclophosphamide; Dactinomycin; Female; Floxuridine; Fluorouracil; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Neoplasms, Experimental; Prednisone; Pyrazoles; Pyrimidines; Triethylenemelamine; Vinblastine; Vincristine | 1966 |
An evaluation of 51 patients with hepatic artery infusion.
Topics: Antineoplastic Agents; Catheterization; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Hepatic Artery; Humans; Injections, Intra-Arterial; Liver Neoplasms; Melphalan; Methotrexate; Neoplasm Metastasis | 1966 |
The response in vitro, of continuous cultures of human lymphoblasts (CCRF-CEM cells) to chemotherapeutic agents.
Topics: Animals; Azaserine; Chloramphenicol; Culture Media; Culture Techniques; Cyclophosphamide; Cytarabine; Dactinomycin; Deoxyuridine; Floxuridine; Fluorouracil; Humans; Hydrocortisone; Lymphocytes; Mechlorethamine; Mercaptopurine; Methotrexate; Mitomycins; Puromycin; Thymidine; Triazines; Vincristine | 1967 |
New concepts in chemotherapy of advanced gastrointestinal cancer.
Topics: Aged; Cyclophosphamide; Female; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1967 |
Determination of certain antitumor agents in mouse blood by microbiologic assay.
Topics: Anilides; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Biological Assay; Floxuridine; Fluorouracil; Mercaptopurine; Methods; Methotrexate; Mice | 1968 |
Radiosensitization of brain tumor cells with a thymidine analogue (bromouridine).
Topics: Astrocytoma; Brain Neoplasms; Bromodeoxyuridine; Culture Techniques; DNA; Floxuridine; Fluorouracil; Follow-Up Studies; Glioma; Humans; Meningioma; Methotrexate; Oligodendroglioma; Radiation-Sensitizing Agents; Thymidine | 1968 |
Responses of freshly cultured tumour cells to certain selected chemotherapeutic agents.
Topics: Adenocarcinoma; Antineoplastic Agents; Chlorambucil; Colchicine; Culture Techniques; Cyclophosphamide; Dactinomycin; Female; Floxuridine; Fluorouracil; Hodgkin Disease; Humans; Melphalan; Mercaptopurine; Methotrexate; Nandrolone; Neoplasms; Nitrogen Mustard Compounds; Norethindrone; Prednisolone; Progesterone; Testosterone; Thiotepa; Uterine Neoplasms; Vinblastine | 1968 |
Protracted intra-arterial chemotherapy with sequential courses of antimitotics and hydrogen peroxyde in the treatment of head and neck tumors.
Topics: Antineoplastic Agents; Catheterization; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrogen Peroxide; Injections, Intra-Arterial; Methods; Methotrexate; Mitomycins; Mitosis; Mouth Neoplasms; Nitrogen Mustard Compounds; Oxygen Inhalation Therapy; Perfusion; Stimulation, Chemical | 1969 |
[Effects of cytostatics and x-rays on nucleic acid metabolism of solid, malignant tumors in vitro].
Topics: Adenine; Animals; Antineoplastic Agents; Carbon Isotopes; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Estriol; Fluorouracil; Formates; Glycine; Hypoxanthines; In Vitro Techniques; Leucine; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasm Proteins; Neoplasms, Experimental; Nucleosides; Orotic Acid; Radiation Effects; RNA, Neoplasm; Testosterone; Thymidine; Triaziquone; Uracil; Uridine | 1970 |
Studies on the chemotherapy of experimental brain tumors: evaluation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea, vincristine, and 5-fluorouracil.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cyclophosphamide; Disease Models, Animal; Ependymoma; Evaluation Studies as Topic; Fluorouracil; Glioma; Injections, Intraperitoneal; Male; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitroso Compounds; Nitrosourea Compounds; Plicamycin; Urea; Vincristine | 1971 |
Practical aspects of investigation and treatment of colorectal cancer.
Topics: Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Humans; Infusions, Parenteral; Liver Function Tests; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Neoplasm Metastasis; Proctoscopy; Prognosis; Rectal Neoplasms; Sex Factors | 1972 |
Comparison of the effects of several inhibitors of the synthesis of nucleic acids upon the viability and progression through the cell cycle of cultured H. Ep. no. 2 cells.
Topics: Antimetabolites; Azaguanine; Carcinoma; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA Replication; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Laryngeal Neoplasms; Mercaptopurine; Methotrexate; Mitosis; Ribonucleosides; Thioguanine; Time Factors; Tritium | 1972 |
Regional arterial chemotherapy for advanced carcinoma of the head and neck. A ten-year review.
Topics: Antimetabolites; Antineoplastic Agents; Carotid Arteries; Catheterization; Digestive System; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Neoplasms; Remission, Spontaneous | 1973 |
Prostatic tumor acid phosphatase production. Influence of antineoplastic agents.
Topics: Acid Phosphatase; Aged; Alkaline Phosphatase; Antineoplastic Agents; Aspartate Aminotransferases; Blood Glucose; Blood Urea Nitrogen; Cyclophosphamide; Cytarabine; Dactinomycin; Drug Therapy, Combination; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Plicamycin; Prostatic Neoplasms; Thiotepa | 1973 |
Combination cancer chemotherapy--a clinical trial on outpatients.
Topics: Adolescent; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasms | 1974 |
Infusion chemotherapy in hepatoma and metastatic liver tumors.
Topics: Adenocarcinoma; Adolescent; Aged; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Parenteral; Leucovorin; Liver Function Tests; Liver Neoplasms; Male; Methotrexate; Middle Aged; Mitomycins; Neoplasm Metastasis; Rectal Neoplasms; Sigmoid Neoplasms | 1967 |
Current problems in the use of the oncolytic drugs.
Topics: Antineoplastic Agents; Busulfan; Carcinoma, Squamous Cell; Child; Chlorambucil; Choriocarcinoma; Dactinomycin; Female; Fluorouracil; Gonadal Steroid Hormones; Hodgkin Disease; Humans; Hydrazines; Leukemia; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Mesenchymoma; Methotrexate; Multiple Myeloma; Nitrogen Mustard Compounds; Ovarian Neoplasms; Pregnancy; Prostatic Neoplasms; Steroids; Testicular Neoplasms; Urethane; Vinblastine; Vincristine; Wilms Tumor | 1968 |
Infusion of liver tumours.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Chemotherapy, Cancer, Regional Perfusion; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Liver Neoplasms; Methotrexate; Neoplasm Metastasis; Radioisotopes | 1968 |
Combination chemotherapy using cyclophosphamide, vincristine, methotrexate and 5-fluorouracil in solid tumors.
Topics: Adenocarcinoma; Adult; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fibrosarcoma; Fluorouracil; Humans; Leiomyosarcoma; Male; Melanoma; Methotrexate; Middle Aged; Neoplasm Metastasis; Osteosarcoma; Pancreatic Neoplasms; Pharyngeal Neoplasms; Prognosis; Sarcoma; Sarcoma, Synovial; Vincristine | 1969 |
[Combination of chemotherapy and electrocoagulation in the treatment of gingival cancers].
Topics: Electrocoagulation; Fluorouracil; Gingival Diseases; Humans; Methotrexate; Mouth Neoplasms; Neoplasms, Muscle Tissue; Vinblastine | 1968 |
Effects of chemotherapeutic agents on two lines of human breast carcinomas in tissue culture.
Topics: Adenocarcinoma, Scirrhous; Breast Neoplasms; Culture Techniques; Fluorouracil; Humans; Methotrexate; Mitosis; Thiotepa | 1969 |
[Polychemotherapy of malignant tumors and hemoblastoses].
Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; Cyclophosphamide; Dysgerminoma; Female; Fluorouracil; Hodgkin Disease; Humans; Kidney Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms, Germ Cell and Embryonal; Skin Neoplasms; Skull Neoplasms; Stomach Neoplasms; Testicular Neoplasms | 1968 |
Current trends in the chemotherapy of brain tumors with special reference to glioblastomas.
Topics: Alkaloids; Antibiotics, Antineoplastic; Antineoplastic Agents; Azaguanine; Blood Vessel Prosthesis; Blood-Brain Barrier; Brain; Brain Neoplasms; Bromodeoxyuridine; Cell Division; Cell Transformation, Neoplastic; Disease Models, Animal; Fluorouracil; Glioblastoma; Humans; Injections, Intra-Arterial; Injections, Spinal; Mechlorethamine; Methotrexate; Nitroso Compounds; Thiotepa; Time Factors; Urea; Vincristine | 1969 |
Chemotherapy of breast cancer by regional intra-arterial infusion.
Topics: Adult; Aged; Antineoplastic Agents; Brachial Artery; Breast Neoplasms; Carotid Arteries; Cyclophosphamide; Female; Femoral Artery; Fluorouracil; Humans; Injections, Intra-Arterial; Methotrexate; Middle Aged; Neoplasm Metastasis; Phyllodes Tumor; Prednisolone; Prognosis; Retrospective Studies; Subclavian Artery; Vinblastine | 1970 |
Linear ichthyosis associated with skeletal abnormalities.
Topics: Abnormalities, Multiple; Bone and Bones; Child; Female; Fluocinolone Acetonide; Fluorouracil; Hand Deformities, Congenital; Humans; Ichthyosis; Methotrexate; Skull; Syndactyly | 1970 |
[Combined antineoplastic agents and surgery in treatment of cancer with multiple localizations: 22 cases].
Topics: Antineoplastic Agents; Cyclophosphamide; Drug Synergism; Female; Fluorouracil; Humans; Male; Methods; Methotrexate; Neoplasm Metastasis; Neoplasms; Prognosis; Vinblastine | 1970 |
The role of heparin in the chemotherapy of solid tumors: preliminary clinical trial in carcinoma of the lung.
Topics: Aged; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Fibrinogen; Fluorouracil; Heparin; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Thioguanine; Vincristine | 1972 |
The surgical management of primary hepatocellular carcinoma in Uganda.
Topics: Adolescent; Adult; Carcinoma, Hepatocellular; Catheterization; Female; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Uganda | 1973 |
Immunotherapeutic studies in mice with the methanol-extraction residue (mer) fraction of BCG: solid tumors.
Topics: Animals; Antigens, Bacterial; BCG Vaccine; Benzopyrenes; Cyclophosphamide; Female; Fibrosarcoma; Fluorouracil; Immunity, Cellular; Male; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methotrexate; Methylcholanthrene; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mycobacterium bovis; Neoplasm Transplantation; Sarcoma, Experimental; Thiotepa; Transplantation, Homologous; Vinblastine | 1973 |
Pseudomonas blepharoconjunctivitis: a complication of combination chemotherapy.
Topics: Antineoplastic Agents; Bacitracin; Blepharitis; Bone Marrow; Breast Neoplasms; Carbenicillin; Cephalothin; Conjunctivitis; Cyclophosphamide; Drug Therapy, Combination; Eyelid Diseases; Female; Fluorouracil; Gentamicins; Humans; Methotrexate; Neomycin; Polymyxins; Prednisone; Pseudomonas aeruginosa; Pseudomonas Infections | 1974 |
A re-examination of the renal blastema graft model for Wilms tumor production.
Topics: Animals; Autopsy; Cell Differentiation; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Drug Therapy, Combination; Female; Fetus; Fluorouracil; Kidney; Kidney Neoplasms; Kidney Transplantation; Male; Methotrexate; Mice; Mice, Inbred Strains; Microscopy, Electron; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Pregnancy; Testicular Neoplasms; Transplantation, Homologous; Vincristine; Wilms Tumor | 1974 |
Heparin anticoagulation as adjuvant to chemotherapy in carcinoma of the lung.
Topics: Aged; Antineoplastic Agents; Blood Coagulation; Carcinoma; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Fibrinogen; Fluorouracil; Heparin; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Radiography; Skin Neoplasms; Thioguanine; Vincristine | 1974 |
[Combined cytostatic treatment of malignant brain tumors (author's transl)].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Child; Child, Preschool; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Glioblastoma; Glioma; Humans; Male; Mercaptopurine; Methotrexate; Middle Aged; Monomethylhydrazine; Neoplasm Metastasis; Vinblastine | 1974 |
On the mode of action of some immunosuppressant drugs.
Topics: Animals; Azathioprine; Fluorouracil; Immunosuppressive Agents; Iodine Isotopes; Male; Methotrexate; Nitrogen Mustard Compounds; Rabbits; Skin Transplantation; Transplantation Immunology; Transplantation, Homologous; Triaziquone | 1968 |
Enhancement of antitumor effect of cyclophosphamide by centrophenoxine.
Topics: Acetates; Animals; Antineoplastic Agents; Busulfan; Central Nervous System Stimulants; Cyclophosphamide; Drug Synergism; Fluorouracil; Meclofenoxate; Mercaptopurine; Methotrexate; Mice; Mitomycins; Sarcoma 180; Vinblastine; Vincristine | 1971 |
Effect of in vivo treatment with L-asparaginase on the in vitro uptake and phosphorylation of some antileukemic agents.
Topics: Animals; Antimetabolites; Asparaginase; Biological Transport; Cytarabine; Dose-Response Relationship, Drug; Fluorouracil; Leucine; Leukemia, Experimental; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Oxidative Phosphorylation; Tetrahydrofolate Dehydrogenase; Time Factors | 1974 |
Major hepatic resection using vascular isolation and hypothermic perfusion.
Topics: Cyclophosphamide; Dactinomycin; Fluorouracil; Hepatectomy; Hepatic Veins; Humans; Hypothermia, Induced; Ligation; Liver Circulation; Liver Neoplasms; Methotrexate; Monitoring, Physiologic; Perfusion; Portal Vein; Postoperative Complications; Radionuclide Imaging; Subphrenic Abscess; Surgical Wound Infection; Technetium; Venae Cavae | 1974 |
Triple drug intra-arterial infusion combined with x-ray therapy and surgery for head and neck cancer.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms; Nose Neoplasms; Pharyngeal Neoplasms; Vinblastine | 1974 |
Synergism of ICRF 159 and radiotherapy in treatment of experimental tumors.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Evaluation Studies as Topic; Fluorouracil; Hydroxyurea; Male; Methotrexate; Mice; Piperazines; Propane; Radiotherapy Dosage; Sarcoma, Experimental | 1974 |
[Chemotherapy of inoperable cancer of the stomach].
Topics: Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Nitrosourea Compounds; Stomach Neoplasms; Vinblastine | 1974 |
The effect of heparin on the cytotoxicity and uptake of anti-neoplastic drugs in cultured Burkitt lymphoma cells.
Topics: Burkitt Lymphoma; Cell Division; Cell Survival; Cells, Cultured; DNA, Neoplasm; Fluorouracil; Heparin; Humans; Mechlorethamine; Mercaptopurine; Methotrexate; Thymidine; Time Factors; Tritium | 1974 |
Intra-arterial chemotherapy for patients with inoperable carcinoma of the pancreas.
Topics: Catheterization; Cyclophosphamide; Fluorouracil; Humans; Injections, Intra-Arterial; Jaundice; Methods; Methotrexate; Pain; Pancreatic Neoplasms; Vincristine | 1974 |
[Hormone therapy and chemotherapy of metastasizing breast cancer. Experiences of the Basle Oncology Center, 1969-72].
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Castration; Cyclophosphamide; Drug Therapy, Combination; Estradiol; Estrogens; Ethinyl Estradiol; Female; Fluorouracil; Hormones; Humans; Hypophysectomy; Methotrexate; Middle Aged; Neoplasm Metastasis; Ovary; Prednisone; Recurrence; Remission, Spontaneous; Vincristine | 1974 |
Chemotherapy in breast cancer.
Topics: Adrenalectomy; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Kinetics; Methotrexate; Mitosis; Remission, Spontaneous; Tourniquets; Vincristine | 1974 |
Sequential administration of two oncostatic drugs: study of modalities for pharmacodynamic potentiation.
Topics: Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Cytarabine; Dactinomycin; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Kinetics; Leukemia L1210; Lomustine; Mathematics; Methotrexate; Mice; Mitomycins; Neoplasm Transplantation; Nitrosourea Compounds; Time Factors; Vincristine | 1974 |
ICRF-159 in treatment of germinal testicular tumor in animals.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Dogs; Drug Therapy, Combination; Fluorouracil; Male; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Piperazines; Propane; Teratoma; Testicular Neoplasms; Vincristine | 1974 |
In vitro estimate of sensitivity of individual human tumors to antitumor agents.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arsenicals; Benzoates; Breast Neoplasms; Carbon Radioisotopes; Carcinoma; Carcinoma, Ehrlich Tumor; Cattle; Depression, Chemical; DNA, Neoplasm; Female; Fluorouracil; Humans; In Vitro Techniques; Iodoacetates; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Lymphoma, Non-Hodgkin; Mechlorethamine; Methotrexate; Mice; Neoplasms; Phenylalanine; Succinate Dehydrogenase; Thymidine; Tritium | 1974 |
Acute leukemia complicating metastatic breast cancer.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; Fluoxymesterone; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Vincristine | 1973 |
Histologic evaluation of treatment of epidermoid carcinoma in the oral cavity with methotrexate and 5-fluorouracil.
Topics: Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Fluorouracil; Humans; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms | 1974 |
Combination chemotherapy in disseminated carcinoma of the breast.
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Evaluation Studies as Topic; Feeding and Eating Disorders; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Nausea; Neoplasm Metastasis; Pneumonia; Prednisone; Thrombocytopenia; Vincristine | 1974 |
Characteristics and response to certain cancer chemotherapeutic agents of an acute lymphocytic leukemia arising in a BALB-c times DBA-2F1 mouse.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Cyclophosphamide; Diethylamines; Disease Models, Animal; Drug Therapy, Combination; Ethylenediamines; Fluorenes; Fluorouracil; Interferon Inducers; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Prednisolone; Thioxanthenes; Vincristine | 1974 |
Additive therapy in the maintenance of remission in acute lymphoblastic leukemia of childhood: the effect of the initial leukocyte count.
Topics: Adolescent; Age Factors; Blood; Brain Neoplasms; Child; Child, Preschool; Dactinomycin; Digestive System; Drug Therapy, Combination; Fluorouracil; Humans; Leukemia, Lymphoid; Leukocyte Count; Mechlorethamine; Methotrexate; Prednisone; Prognosis; Time Factors | 1974 |
Combination chemotherapy: the interaction of methotrexate and 5-fluorouracil.
Topics: Animals; Cell Line; Cells, Cultured; Drug Antagonism; Drug Interactions; Drug Therapy, Combination; Fluorouracil; Leukemia L1210; Leukemia, Lymphoid; Methotrexate; Mice; Purines; Spectrophotometry; Tritium; Uracil Nucleotides | 1973 |
Arterial infusion and radiation therapy in the treatment of advanced cancer of the nasal cavity and paranasal sinuses.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Carotid Artery, External; Carotid Artery, Internal; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Lymphatic Metastasis; Maxillary Artery; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Nose Neoplasms; Paranasal Sinus Neoplasms | 1973 |
Changes in the deoxyribonucleoside triphosphate pools of mouse 5178Y lymphoma cells following exposure to methotrexate or 5-fluorouracil.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyribonucleotides; Deoxyuridine; DNA, Neoplasm; Fluorouracil; Guanosine; Leukemia, Experimental; Leukemia, Lymphoid; Methotrexate; Mice; Phosphates; Thymidine; Tritium | 1973 |
Letter: Metastatic kidney cancer treated with multiple drug therapy at the Rotterdam Radiotherapy Institute.
Topics: Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Kidney Neoplasms; Leucovorin; Methotrexate; Neoplasm Metastasis; Vincristine | 1974 |
[Results of polycytostatic therapy in tumorous pleural effusion (author's transl)].
Topics: Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Mesothelioma; Methotrexate; Middle Aged; Neoplasm Metastasis; Pleural Effusion; Pleural Neoplasms; Vinblastine | 1974 |
Toxicity, clearance and distribution of endotoxin in mice as influenced by actinomycin D, cycloheximide, -amanitin and lead acetate.
Topics: Acetates; Animals; Azathioprine; Chromium Isotopes; Cycloheximide; Cyclophosphamide; Dactinomycin; Endotoxins; Escherichia coli; Fluorouracil; Injections, Intraperitoneal; Injections, Intravenous; Lead; Lethal Dose 50; Male; Methotrexate; Mice; Mycotoxins; Protein Biosynthesis; RNA; Salmonella; Time Factors | 1972 |
Results in 169 patients with cancer of the head and neck treated by intra-arterial infusion therapy.
Topics: Antineoplastic Agents; Brachial Artery; Brachiocephalic Trunk; Carcinoma, Squamous Cell; Carotid Artery, Internal; Catheterization; Cyclophosphamide; Dactinomycin; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Laryngeal Neoplasms; Melanoma; Methods; Methotrexate; Mouth Neoplasms; Neoplasms; Osteosarcoma; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms; Skull Neoplasms; Vinblastine | 1972 |
Antigenicity of C 3 H mammary carcinoma in isogenetic hosts: preliminary studies.
Topics: Animals; Antigens, Neoplasm; Carcinoma; Fluorouracil; Immunologic Techniques; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mice, Inbred C3H | 1973 |
Intra-arterial infusion for head and neck cancers.
Topics: Aged; Antineoplastic Agents; Brachiocephalic Trunk; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Female; Fluoresceins; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Leukocyte Count; Male; Methods; Methotrexate; Neoplasm Recurrence, Local; Neoplasms; Vinblastine | 1973 |
Differential lethal effect of cytotoxic agents on proliferating and nonproliferating lymphoid cells.
Topics: Animals; Antibody Formation; Antineoplastic Agents; B-Lymphocytes; Cell Division; Cyclophosphamide; Cytarabine; Dactinomycin; Dose-Response Relationship, Drug; Erythrocytes; Fluorouracil; Hemolytic Plaque Technique; Male; Methotrexate; Mice; Mice, Inbred AKR; Nitrogen Mustard Compounds; Radiation Effects; Sheep; Vincristine | 1973 |
Selective alteration of immunocompetence with methotrexate and 5-fluorouracil.
Topics: Animals; Antibody Formation; Antigen-Antibody Complex; Dermatitis, Contact; Female; Fluorouracil; Graft Rejection; Hemolytic Plaque Technique; Hypersensitivity; Immunity, Cellular; Immunoglobulin M; Immunosuppression Therapy; Leucovorin; Male; Methotrexate; Mice; Mice, Inbred Strains; Oxazoles; Serum Albumin, Bovine; Skin Transplantation; Transplantation, Homologous | 1974 |
Synergism of methotrexate with imuran and with 5-fluorouracil and their effects on hemolysin plaque-forming cell production in the mouse.
Topics: Animals; Antibody-Producing Cells; Azathioprine; Drug Synergism; Female; Fluorouracil; Hemolytic Plaque Technique; Methotrexate; Mice; Mice, Inbred C3H; Time Factors | 1974 |
Influence of chemotherapeutic agents on the antibacterial activity of normal and leukemic sera.
Topics: Antineoplastic Agents; Blood Bactericidal Activity; Carmustine; Cell Membrane; Complement System Proteins; Cyclophosphamide; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Escherichia coli; Fluorouracil; Humans; Immunoglobulins; Leukemia; Mechlorethamine; Methotrexate; Microbial Sensitivity Tests; Muramidase; Prednisone; Vincristine | 1974 |
Selective immunosuppression by drugs in balanced immune responses.
Topics: Animals; Antibody Formation; Cell Division; Clone Cells; Cytarabine; Cytotoxicity Tests, Immunologic; Fluorouracil; Graft Rejection; Hemolytic Plaque Technique; Hypersensitivity, Delayed; Immunity, Cellular; Immunosuppressive Agents; Lymphocytes; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mice, Inbred A; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasm Transplantation; Skin Transplantation; Spleen; Transplantation, Homologous | 1974 |
Acute leukemia following cytotoxic chemotherapy.
Topics: Adenocarcinoma; Adult; Female; Fluorouracil; Humans; Leukemia, Myeloid, Acute; Methotrexate; Ovarian Neoplasms; Prednisone; Thiotepa | 1972 |
Cancer chemotherapy. I. Methods, agents and overall results in 400 patients.
Topics: Adenocarcinoma; Amides; Androgens; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Estrogens; Female; Fluorouracil; Glucocorticoids; Head; Head and Neck Neoplasms; Humans; Imidazoles; Lung Neoplasms; Male; Mechlorethamine; Melanoma; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasms; Progesterone; Rectal Neoplasms; Sarcoma; Thiotepa; Triazenes | 1972 |
[Polychemotherapy of broncho-pulmonary cancer: report of clinical research].
Topics: Adenocarcinoma; Adult; Aged; Bronchial Neoplasms; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Thiotepa; Vinblastine | 1972 |
[The effect of various antibiotics, corticosteroids and cytostatic preparations on the morphology of experimental aspergillosis].
Topics: Animals; Antineoplastic Agents; Aspergillosis; Aspergillus fumigatus; Brain; Chlortetracycline; Cyclophosphamide; Dexamethasone; Fluorouracil; Hydrocortisone; Inflammation; Kidney; Liver; Lung; Mercaptopurine; Methotrexate; Mice; Myocardium; Penicillin V; Spleen; Streptomycin | 1972 |
Determination of endotoxicity in bacterial vaccines.
Topics: Acetone; Animals; Bacterial Vaccines; Body Weight; Cyclophosphamide; Dactinomycin; Drug Synergism; Escherichia coli; Fluorouracil; Hot Temperature; Injections, Intraperitoneal; Lethal Dose 50; Lipopolysaccharides; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred BALB C; Mitomycins; Pertussis Vaccine; Polysaccharides, Bacterial; Pseudomonas aeruginosa; Salmonella typhi; Species Specificity; Typhoid-Paratyphoid Vaccines; Vaccines, Attenuated | 1973 |
[Chemotherapy of gastric cancer].
Topics: Demecolcine; Fluorouracil; Humans; Methotrexate; Stomach Neoplasms | 1972 |
Results of 27 cases with hepatic metastases treated by combination chemotherapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Jaundice; Liver; Liver Neoplasms; Methotrexate; Neoplasm Metastasis; Radionuclide Imaging; Rectal Neoplasms; Vincristine | 1972 |
[Acid-base equilibrium under cytostatic therapy].
Topics: Acid-Base Equilibrium; Adolescent; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Female; Fluorouracil; Humans; Hydrogen-Ion Concentration; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms; Vinblastine | 1972 |
[Polychemotherapy of primary and secondary brain tumors].
Topics: Adult; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Hydrazines; Mercaptopurine; Methotrexate; Neoplasm Metastasis; Vinblastine | 1972 |
Five-drug combination chemotherapy for disseminated adenocarcinoma.
Topics: Adenocarcinoma; Adrenal Gland Neoplasms; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Humans; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Ovarian Neoplasms; Parotid Neoplasms; Prednisone; Time Factors; Vincristine | 1972 |
Study on the sensitivity test of carcinostatic agents by acid phosphatase activity.
Topics: Acid Phosphatase; Adult; Aged; Animals; Antineoplastic Agents; Chromomycins; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Mechlorethamine; Methotrexate; Mice; Middle Aged; Mitomycins; Neoplasms; Neoplasms, Experimental; Rats; Stomach Neoplasms; Vincristine | 1972 |
Changes in the pyrimidine deoxynucleoside triphosphate pools of L5178Y cells after their exposure to methotrexate and 5-fluorouracil.
Topics: Adenosine Triphosphate; Animals; Cell Line; Deoxyribonucleotides; Fluorouracil; Leukemia, Experimental; Methotrexate; Mice; Thymine Nucleotides | 1972 |
Nonbacterial pneumonitis with multidrug antineoplastic therapy in breast carcinoma.
Topics: Adenocarcinoma; Adrenalectomy; Adult; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Pneumonia; Prednisone; Radiography; Time Factors; Vincristine | 1973 |
[Oral, florid papillomatosis].
Topics: Adrenal Cortex Hormones; Aged; Female; Fluorouracil; Humans; Injections, Intramuscular; Lip Neoplasms; Male; Methotrexate; Mouth Neoplasms; Neoplasm Recurrence, Local; Papilloma | 1973 |
Cecal necrosis and perforation with systemic chemotherapy.
Topics: Adult; Asparaginase; Breast Neoplasms; Cecal Diseases; Child; Cytarabine; Daunorubicin; Female; Fluorouracil; Humans; Intestinal Perforation; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Necrosis; Prednisone; Thioguanine; Vincristine | 1973 |
[Iatrogenic diabetic coma. Contribution to adverse effects of cytostatic therapy].
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Diabetic Coma; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Vincristine | 1973 |
[Results of single- and multiple-drug treatment of 183 cases of inoperable bronchopulmonary cancer].
Topics: Bronchial Neoplasms; Cyclophosphamide; Drug Synergism; Fluorouracil; Humans; Lung Neoplasms; Methods; Methotrexate; Time Factors | 1973 |
Determination of therapeutic index of drugs by in vitro sensitivity tests using human host and tumor cell suspensions.
Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Fluorouracil; Humans; In Vitro Techniques; Methotrexate; Neoplasms; Penicillamine; Thymidine; Time Factors; Tritium | 1973 |
Combination therapy of solid tumors using 1,3-bis(2-chloroethyl)-1-nitrosourea (NCNU), vincristine, methotrexate, and 5-fluorouracil.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Carmustine; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms; Thyroid Neoplasms; Uterine Neoplasms; Vincristine | 1973 |
Results in fifty cases of advanced squamous cell carcinoma of the head and neck treated by intravenous chemotherapy.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Combinations; Epiglottis; Female; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Nausea; Neoplasms; Tongue Neoplasms; Vincristine | 1973 |
Combination chemotherapy in disseminated carcinoma of the breast.
Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Drug Synergism; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Remission, Spontaneous; Time Factors; Vincristine | 1973 |
[Immediate results of polychemotherapy of patients with 3-4 stage lung cancer].
Topics: Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Humans; Injections, Intravenous; Lung Neoplasms; Methotrexate; Vinblastine | 1973 |
Chemotherapeutic studies in bronchogenic carcinoma by the Austrian study group.
Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Austria; Carcinoma, Bronchogenic; Cyclophosphamide; Female; Fluorouracil; Humans; Leukocyte Count; Lung Neoplasms; Male; Methotrexate; Middle Aged; Time Factors; Vinblastine | 1973 |
[Experiences on in vitro testing of cytostatic sensitivity (oncobiogram) in gynecological tumors].
Topics: Antineoplastic Agents; Cyclophosphamide; Drug Resistance; Female; Fluorouracil; Genital Neoplasms, Female; Humans; Methotrexate; Nitrogen Mustard Compounds; Ovarian Neoplasms; Remission, Spontaneous; Triaziquone; Uterine Cervical Neoplasms; Uterine Neoplasms; Vinblastine; Vulvar Neoplasms | 1973 |
Gynecologic oncology.
Topics: Alkylating Agents; Ascites; Biopsy; Dactinomycin; Endometrium; Female; Fluorouracil; Genital Neoplasms, Female; Humans; Methotrexate; Neoplasm Recurrence, Local; Ovarian Neoplasms; Pelvic Neoplasms; Pleural Effusion; Uterine Cervical Neoplasms; Vaginal Neoplasms; Vulvar Neoplasms | 1973 |
The problems of drug treatment of breast cancer.
Topics: Age Factors; Alkylating Agents; Androgens; Bone Neoplasms; Breast Neoplasms; Corticosterone; Drug Combinations; Estrogens; Female; Fluorouracil; Follow-Up Studies; Hormones; Humans; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Pleural Effusion; Pleural Neoplasms; Progestins; Time Factors; Vinblastine; Vincristine | 1973 |
Activation of virus production in vaccinia virus transformed cells by methotrexate.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Complement Fixation Tests; Fluorouracil; Humans; In Vitro Techniques; Inclusion Bodies, Viral; Methotrexate; Mice; Mitomycins; Time Factors; Vaccinia virus; Viral Plaque Assay; Virus Replication | 1973 |
Disseminated breast carcinoma. Treatment with combination chemotherapy.
Topics: Adenocarcinoma; Adult; Breast Neoplasms; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Vincristine | 1973 |
Multiple-drug therapy for malignant solid tumors in adults.
Topics: Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Leukopenia; Methotrexate; Neoplasms; Thrombocytopenia; Vincristine | 1973 |
[Combined therapy of bronchial carcinoma. Chemotherapeutic review].
Topics: Bronchial Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Methotrexate; Vinblastine | 1973 |
The role of thymidylate synthetase inhibitors in bromodeoxyuridine-induced neoplasia in Drosophila.
Topics: Animals; Bromodeoxyuridine; Centrifugation, Density Gradient; DNA; Drosophila; Fluorine; Fluorouracil; Idoxuridine; Larva; Methotrexate; Methyltransferases; Neoplasms, Experimental; Thymidine; Thymidylate Synthase; Tritium | 1973 |
[Cytostatic combination therapy in metastatic breast cancer].
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Remission, Spontaneous; Vincristine | 1973 |
Cyclical combination chemotherapy in advanced breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Hypophysectomy; Methotrexate; Norethindrone; Remission, Spontaneous; Time Factors; Vincristine | 1973 |
The treatment of jaundice due to liver metastases by quadruple chemotherapy.
Topics: Aged; Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Humans; Jaundice; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Vincristine | 1973 |
Peripheral nucleated cell count as a method of assessing the response of antileukemic agents in Rauscher virus-diseased mice.
Topics: Animals; Antineoplastic Agents; Blood; Busulfan; Carbamates; Cell Count; Chlorambucil; Cyclophosphamide; Dose-Response Relationship, Drug; Ethylamines; Fluorouracil; Lethal Dose 50; Leukemia, Experimental; Male; Mercaptopurine; Methotrexate; Mice; Nitrogen Mustard Compounds; Propylamines; Rauscher Virus; Sulfanilamides | 1973 |
Effect of methotrexate on cells chronically infected with vaccinia virus.
Topics: Cell Count; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Drug Resistance; Fluorouracil; Humans; Methotrexate; Mitomycins; Vaccinia virus; Virus Replication | 1973 |
Evolution of a practical policy for chemotherapy of carcinoma of the breast.
Topics: Blood Cell Count; Breast Neoplasms; Cyclophosphamide; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Injections, Intravenous; Methotrexate; Time Factors; Vinblastine; Vincristine | 1973 |
[Cooper's combination chemotherapy of metastasizing breast carcinoms].
Topics: Adult; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Vincristine | 1973 |
[Therapy of metastasizing solid tumors with cyclophosphamide, methotrexate, vincristine and 5-fluorouracil].
Topics: Adolescent; Adult; Aged; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Methods; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms; Vincristine | 1973 |
Cancer chemotherapy by intra-arterial infusion with adriamycin.
Topics: Adult; Alopecia; Anemia; Doxorubicin; Electrocardiography; Female; Femoral Artery; Fluorouracil; Heart; Humans; Infusions, Parenteral; Injections, Intra-Arterial; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasms; Thrombocytopenia | 1973 |
Biological characterization of human tumours by means of organ culture and individualized cytostatic cancer treatment.
Topics: Antineoplastic Agents; Biological Assay; Biopsy; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Male; Melphalan; Methotrexate; Neoplasms; Organ Culture Techniques; Triaziquone; Vinblastine; Vincristine | 1973 |
Intra-arterial cancer chemotherapy with combined anticancer agents.
Topics: Adult; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Deoxycytidine; Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intra-Arterial; Leukopenia; Liver Neoplasms; Methotrexate; Middle Aged; Mitomycins; Neoplasms, Connective Tissue; Pyridoxal Phosphate; Stomach Neoplasms; Vinblastine; Vincristine | 1973 |
An evaluation of five drug combination chemotherapy in the management of recurrent carcinoma of the breast.
Topics: Administration, Oral; Adult; Aged; Blood Cell Count; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Injections, Intravenous; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prednisone; Remission, Spontaneous; Vincristine | 1974 |
The effect of cancer chemotherapeutic agents on fibrin formation and stabilization in vitro.
Topics: Antineoplastic Agents; Asparaginase; Blood Coagulation Tests; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Electric Conductivity; Factor XIII; Fibrin; Fibrinolysis; Fluorouracil; Humans; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Mechlorethamine; Methotrexate; Microscopy, Electron; Nitrogen Mustard Compounds; Solubility; Triazenes; Urea; Vinblastine; Vincristine | 1974 |
Letter: Chemotherapy of disseminated malignant tumours.
Topics: Bronchial Neoplasms; Cyclophosphamide; Cytarabine; Dactinomycin; Fluorouracil; Humans; Methotrexate; Vincristine | 1974 |
Cyclical combination chemotherapy for advanced breast carcinoma.
Topics: Adrenalectomy; Adult; Alopecia; Bone Marrow; Bone Neoplasms; Breast Neoplasms; Castration; Cyclophosphamide; Drug Combinations; Female; Fluorouracil; Humans; Liver; Liver Neoplasms; Lung Neoplasms; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Thrombocytopenia | 1974 |
Carcinoembryonic antigen in breast cancer patients: serum levels and disease progress.
Topics: Adrenalectomy; Adult; Aged; Breast Neoplasms; Carcinoembryonic Antigen; Castration; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Ovary; Prednisone; Radioimmunoassay; Time Factors; Vincristine | 1974 |
Combination radiotherapy and chemotherapy for P388 lymphocytic leukemia in vivo.
Topics: Alanine; Animals; Cisplatin; Cobalt Radioisotopes; Cyclophosphamide; Cytarabine; Female; Fluorouracil; Leukemia, Experimental; Leukemia, Lymphoid; Male; Mechlorethamine; Methotrexate; Mice; Neoplasm Transplantation; Prednisone; Procarbazine; Prognosis; Radioisotope Teletherapy; Radiotherapy Dosage; Transplantation, Homologous; Vinblastine; Vincristine | 1974 |
Cyclical combination chemotherapy in advanced breast cancer.
Topics: Age Factors; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hypophysectomy; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Norethindrone; Vincristine | 1974 |
[Recent advances in the treatment of Ewing's sarcoma (author's transl)].
Topics: Adolescent; Adult; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Synergism; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Prognosis; Sarcoma, Ewing; Time Factors; Vincristine | 1974 |
[Combination chemotherapy with cyclophosphamide, methotrexate, 5-fluoro-uracil, and vincristine in solid metastasized tumours (author's transl)].
Topics: Adult; Aged; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Patient Care Planning; Remission, Spontaneous; Time Factors; Vincristine | 1974 |
[Chemotherapy of cancer. Hints for continuing medical education].
Topics: Antineoplastic Agents; Busulfan; Chlorambucil; Cyclophosphamide; Cytarabine; Daunorubicin; Education, Medical, Continuing; Fluorouracil; Humans; Melphalan; Mercaptopurine; Methotrexate; Neoplasms; Procarbazine; Triaziquone; Vinblastine; Vincristine | 1974 |
Five-drug therapy in advanced breast cancer: factors influencing toxicity and response.
Topics: Administration, Oral; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Tolerance; Female; Fluorouracil; Follow-Up Studies; Humans; Injections, Intravenous; Leukopenia; Methotrexate; Prednisone; Vincristine | 1974 |
The effects of cytostatic drugs on transplanted tumours. An investigation of the correlation between in vivo and in vitro results.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cricetinae; Cytarabine; Daunorubicin; Fluorouracil; Melanoma; Methotrexate; Mice; Neoplasm Transplantation; Plasmacytoma; Procarbazine; Rats; Thymidine; Tritium; Uridine | 1974 |
Primary mediastinal choriocarcinoma in the male.
Topics: Adult; Choriocarcinoma; Cyclophosphamide; Cytodiagnosis; Drug Therapy, Combination; Fluorouracil; Humans; Male; Mediastinal Neoplasms; Methotrexate; Neoplasm Metastasis; Radiography; Remission, Spontaneous; Sex Factors; Vincristine | 1974 |
[Progress in chemotherapy of solid tumors and malignant lymphomas (continued)].
Topics: Adult; Antineoplastic Agents; Carcinoma; Choriocarcinoma; Female; Fluorouracil; Gonadal Steroid Hormones; Hodgkin Disease; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neoplasms; Pregnancy | 1967 |
Anti-tumour agents on antibody-forming cells in vitro.
Topics: Animals; Antibody-Producing Cells; Antineoplastic Agents; Cell Line; Cells, Cultured; Culture Techniques; Erythrocytes; Fluorouracil; Guinea Pigs; Hemolytic Plaque Technique; Male; Mechlorethamine; Mercaptopurine; Methotrexate; Mice; Sheep; Spleen; Vinblastine | 1970 |
Antibody plaque reduction in vitro and in vivo: a rapid assay for immunosuppressive agents.
Topics: Animals; Antibody Formation; Antibody-Producing Cells; Antigens; Antilymphocyte Serum; Cortisone; Cyclophosphamide; Erythrocytes; Fluorouracil; Hemolytic Plaque Technique; Immunosuppressive Agents; Lymphocytes; Mercaptopurine; Methotrexate; Mice; Radiation Effects; Sheep; Spleen; Vinblastine | 1969 |
Regional chemotherapy of cancer of the head and neck.
Topics: Antineoplastic Agents; Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Leucovorin; Melanoma; Melphalan; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Paranasal Sinus Neoplasms; Sarcoma; Thiotepa; Vinblastine | 1966 |
Systemic chemotherapy for carcinoma of the cervix.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Humans; Hydroxyurea; Mechlorethamine; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Progestins; Thiotepa; Urea; Uterine Cervical Neoplasms | 1967 |
Current cancer concepts. The place of chemotherapy in management.
Topics: Breast Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Humans; Methotrexate; Testosterone; Thiotepa | 1967 |
Killing of cells in bacterial colonies.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Azaserine; Chloramphenicol; Enterococcus faecalis; Escherichia coli; Fluorouracil; Kinetics; Methotrexate; Nitroso Compounds; Penicillin G; Urea | 1967 |
The effect of systemic chemotherapeutic agents upon retional lymph node cell trapping.
Topics: Animals; Chromium Isotopes; Dogs; Fluorouracil; Lymph Nodes; Methotrexate; Thiotepa | 1967 |
Experimental studies of human bladder cancer: heterotransplantation to the hamster cheek pouch.
Topics: Animals; Antineoplastic Agents; Cheek; Cricetinae; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Methotrexate; Mitomycins; Neoplasm Metastasis; Neoplasm Transplantation; Streptonigrin; Thiotepa; Transplantation Immunology; Urinary Bladder Neoplasms; Vinblastine; Vincristine | 1967 |
Influence of five anti-cancer drugs on the induction and growth of experimental mammary cancers: comparison with ovariectomy.
Topics: Animals; Antineoplastic Agents; Castration; Cyclophosphamide; Female; Fluorouracil; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Methotrexate; Methylcholanthrene; Rats; Thiotepa; Vinblastine | 1968 |
[Our experiences with polychemotherapy of malignant endothoracic tumors (103 cases)].
Topics: Adenocarcinoma; Adult; Androgens; Antineoplastic Agents; Azirines; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Colchicine; Cyclophosphamide; Drug Synergism; Female; Fluorouracil; Glucocorticoids; Humans; Hydrazines; Injections, Intravenous; Male; Mechlorethamine; Methotrexate; Neoplasm Metastasis; Pleural Neoplasms; Thiotepa; Vinblastine | 1968 |
[Antineoplastic polychemotherapy in thoracic pathology].
Topics: Adrenalectomy; Aged; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Cortisone; Cyclophosphamide; Drug Synergism; Ethinyl Estradiol; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Hydrazines; Hypophysectomy; Kidney Neoplasms; Lung Neoplasms; Male; Melanoma; Melphalan; Mesothelioma; Methotrexate; Middle Aged; Nandrolone; Neoplasm Metastasis; Ovarian Neoplasms; Podophyllin; Sarcoma; Thiotepa; Vinblastine | 1968 |
[3 years of polychemotherapy of pleuro-pulmonary cancer. Apropos of 95 cases].
Topics: Androgens; Antibiotics, Antineoplastic; Antineoplastic Agents; Ascorbic Acid; Azirines; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Synergism; Fluorouracil; Glucocorticoids; Humans; Hydrazines; Injections, Intramuscular; Injections, Intravenous; Lectins; Lung Neoplasms; Mechlorethamine; Mercaptopurine; Mesothelioma; Methotrexate; Phenylbutazone; Pleural Neoplasms; Thiotepa; Vinblastine | 1968 |
[Trial treatment of bronchial cancer by polychemotherapy].
Topics: Antineoplastic Agents; Azirines; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Colchicine; Cyclophosphamide; Drug Synergism; Fluorouracil; Humans; Hydrazines; Injections, Intravenous; Mechlorethamine; Mercaptopurine; Methotrexate; Thiotepa; Vinblastine | 1968 |
Cytotoxic drug and hormone therapy after adrenalectomy for advanced breast cancer.
Topics: Adrenalectomy; Androgens; Antineoplastic Agents; Breast Neoplasms; Cortisone; Cyclophosphamide; Diethylstilbestrol; Estrogens; Female; Fluorouracil; Fluoxymesterone; Humans; Mechlorethamine; Methotrexate; Testosterone; Thiotepa; Vinblastine; Vincristine | 1968 |
Relative effects of varying concentrations of cytotoxic drugs in vitro on tumour and reticulo-endothelial tissue.
Topics: Animals; Antineoplastic Agents; DNA; DNA, Neoplasm; Fluorouracil; Glucose; In Vitro Techniques; Mammary Neoplasms, Experimental; Mechlorethamine; Melphalan; Methotrexate; Mice; Mononuclear Phagocyte System; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; RNA; RNA, Neoplasm; Spleen; Thiotepa; Tritium; Vinblastine | 1968 |
[Experimental research on intra-arterial antiblastic chemotherapy. I. Clinical behavior of blood crasis and some other blood chemical constants in the rabbit].
Topics: Animals; Antineoplastic Agents; Blood; Blood Cell Count; Blood Glucose; Blood Proteins; Female; Fluorouracil; Injections, Intra-Arterial; Male; Methotrexate; Nitrogen; Rabbits; Thiotepa | 1968 |
Cytotoxic agents in the treatment of malignant disease.
Topics: Antimetabolites; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Female; Fluorouracil; Hodgkin Disease; Humans; Hydrazines; Intestinal Neoplasms; Melphalan; Methotrexate; Multiple Myeloma; Ovarian Neoplasms; Pregnancy; Thiotepa; Vinblastine | 1968 |
[The chemotherapy of cancer].
Topics: Adult; Alkylating Agents; Antimetabolites; Antineoplastic Agents; Dactinomycin; Female; Fluorouracil; Hodgkin Disease; Humans; Lung Neoplasms; Male; Melphalan; Methotrexate; Middle Aged; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum; Radiography; Sarcoma, Ewing; Thiotepa; Vincristine | 1967 |
Sensitivity of Nakahara-Fukuoka sarcoma to antitumor agents, especially to purine analogs.
Topics: Animals; Antineoplastic Agents; Busulfan; Cyclophosphamide; Female; Fluorouracil; Hydrocortisone; Mechlorethamine; Mercaptopurine; Methotrexate; Mice; Mitomycins; Purines; Sarcoma, Experimental; Thioguanine; Thiotepa; Uracil | 1969 |
[Regional chemotherapy in far advanced forms of cancer of the uterine cervix].
Topics: Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Thiotepa; Uterine Cervical Neoplasms | 1969 |
[Animal experimental studies on the immunosuppressive effect of cytostatic agents].
Topics: Animals; Antineoplastic Agents; Busulfan; Carcinogens; Cyclophosphamide; Fluorouracil; Hemagglutination Tests; Immunosuppressive Agents; Male; Mannomustine; Mercaptopurine; Methotrexate; Mitomycins; Rats; Spleen; Thiotepa; Triaziquone; Vinblastine | 1969 |
Chemotherapy and radiation therapy together to treat cancer.
Topics: Antineoplastic Agents; Cell Division; Cyclophosphamide; DNA, Neoplasm; Female; Fluorouracil; Heparin; Humans; Hyperbaric Oxygenation; Injections, Intra-Arterial; Injections, Intravenous; Male; Methotrexate; Neoplasms; Nitrogen; Oxygen; Perfusion; Phlebitis; Therapeutic Irrigation; Thiotepa; Time Factors; Vinblastine | 1970 |
Metastatic carcinoma of the male breast treated with bilateral adrenalectomy and chemotherapy.
Topics: Adrenalectomy; Aged; Breast Neoplasms; Castration; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Sex Factors; Thiotepa | 1970 |
[Antineoplastic chemotherapy in gynecology; some generalizations].
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Cyclophosphamide; Female; Fluorouracil; Genital Neoplasms, Female; Humans; Methotrexate; Thiotepa | 1967 |
Immunosuppressive methods and antilymphocytic serum.
Topics: Antilymphocyte Serum; Azathioprine; Colchicine; Cortisone; Cyclophosphamide; Dactinomycin; DNA; Drainage; Fluorouracil; Histocompatibility Testing; Humans; Immune Tolerance; Immunosuppressive Agents; Lymph; Mercaptopurine; Methods; Methotrexate; Prednisone; Radiotherapy; Radiotherapy Dosage; Rh-Hr Blood-Group System; RNA; Splenectomy; Thymectomy; Transplantation Immunology; Triethylenemelamine | 1970 |
Systemic chemotherapy for advanced breast cancer.
Topics: Adrenal Cortex Hormones; Adult; Aged; Androgens; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Estrogens; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Nitrogen Mustard Compounds; Prognosis; Retrospective Studies; Thiotepa; Time Factors; Vinblastine | 1970 |
[Chemotherapy of solid tumors].
Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Synergism; Fluorouracil; Humans; Melanoma; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Skin Neoplasms; Thiotepa | 1970 |
[Chemotherapy of inoperable bronchial carcinoma].
Topics: Age Factors; Aged; Antineoplastic Agents; Bronchial Neoplasms; Cyclophosphamide; Diagnosis, Differential; Drug Synergism; Female; Fluorouracil; Fructose; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Mitomycins; Neoplasm Metastasis; Prognosis; Radiography; Radiotherapy, High-Energy; Vinblastine; Vitamin A | 1971 |
[Comparative evaluation of thiphosphamide, cyclophosphane, methotrexate and 5-fluorouracil in the treatment of breast cancer].
Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Menopause; Menstruation; Methotrexate; Middle Aged; Neoplasm Metastasis; Thiotepa | 1971 |
[Oncological treatment of gastrointestinal carcinoma].
Topics: Adolescent; Adult; Aged; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Methotrexate; Middle Aged; Thiotepa; Vinblastine | 1970 |
Sequential liver scanning.
Topics: Adult; Breast Neoplasms; Chloroquine; Colonic Neoplasms; Dactinomycin; Emetine; Estrogens; Female; Fluorouracil; Gold Colloid, Radioactive; Humans; Liver Abscess, Amebic; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Radionuclide Imaging; Thiotepa | 1969 |
Phase I study of phenesterin (NSC-104469).
Topics: Administration, Oral; Adult; Aged; Androgens; Antineoplastic Agents; Blood Cell Count; Blood Platelets; Bone Marrow Diseases; Breast Neoplasms; Chlorambucil; Cholestanes; Cyclophosphamide; Estrogens; Fluorouracil; Glucocorticoids; Humans; Leukocyte Count; Leukopenia; Methotrexate; Middle Aged; Nitrogen Mustard Compounds; Secosteroids; Stomatitis; Tachycardia; Thiotepa; Vincristine | 1971 |
The use of chemotherapy in lung cancer (controlled trials).
Topics: Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Dactinomycin; Drug Synergism; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Nitrogen Mustard Compounds; Thiotepa | 1971 |
The "sensitivity" of resting and dividing cells.
Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Bacillus cereus; Bacteriolysis; Carbenicillin; Cell Survival; Cephalothin; Chlortetracycline; Colistin; Daunorubicin; Enterococcus faecalis; Escherichia coli; Fluorouracil; Mechlorethamine; Mercaptopurine; Methotrexate; Microbial Sensitivity Tests; Nucleosides; Penicillins; Pseudomonas; Rifampin; Sarcina; Staphylococcus; Sulfonamides; Triazenes | 1971 |
The "sensitivity" of resting and dividing cells.
Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Bacillus cereus; Bacteriolysis; Carbenicillin; Cell Survival; Cephalothin; Chlortetracycline; Colistin; Daunorubicin; Enterococcus faecalis; Escherichia coli; Fluorouracil; Imidazoles; Mechlorethamine; Mercaptopurine; Methotrexate; Microbial Sensitivity Tests; Nucleosides; Penicillins; Pseudomonas; Rifampin; Sarcina; Staphylococcus; Sulfonamides; Triazenes | 1970 |
Hypogastric artery infusion and radiation therapy for advanced squamous cell carcinoma of the cervix.
Topics: Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Methods; Methotrexate; Postoperative Complications; Radioisotope Teletherapy; Time Factors; Uterine Cervical Neoplasms | 1972 |
Combination chemotherapy in the treatment of metastatic hemangiopericytoma.
Topics: Administration, Oral; Cyclophosphamide; Dactinomycin; Fluorouracil; Hemangiopericytoma; Humans; Injections, Intravenous; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Radiography; Vincristine | 1972 |
Treatment of squamous cell carcinoma of the head and neck by chemotherapy.
Topics: Administration, Oral; Carcinoma, Squamous Cell; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Methotrexate; Neoplasm Metastasis; Neoplasms; Radiography | 1972 |
Intra-arterial infusion. A seven-year study.
Topics: Carcinoma, Squamous Cell; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Iowa; Methotrexate; Neoplasms | 1972 |
Chemotherapy in the management of metastatic cancer of unknown primary site.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Carcinoma; Carcinoma, Squamous Cell; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms; Prednisone; Vincristine | 1972 |
Expectations and pitfalls of chemotherapy in a university cancer clinic.
Topics: Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Gastrointestinal Neoplasms; Hospitals, Teaching; Humans; Lung Neoplasms; Male; Melanoma; Methotrexate; Neoplasms; Outpatient Clinics, Hospital; Sarcoma; South Carolina; Vincristine | 1972 |
Chemotherapy of breast carcinoma.
Topics: Adult; Amines; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; Humans; Imidazoles; Mercaptopurine; Methotrexate; Middle Aged; Mitomycins; Neoplasm Metastasis; Prednisone; Triazines; Vincristine | 1972 |
[Clinical and experimental results of interstitial Brachy-Curie-therapy combined with radiation sensitizing agents in infiltrative growing brain neoplasms].
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Carcinosarcoma; Cytidine; Fluorouracil; Guanosine; Iridium; Methotrexate; Neoplasms, Experimental; Radiation-Sensitizing Agents; Rats; Thymine | 1972 |
[Continuous infusion method of antitumor agents through intra-aortic catheterization].
Topics: Antineoplastic Agents; Aorta; Cytarabine; Fluorouracil; Humans; Injections, Intra-Arterial; Methotrexate; Mitomycins | 1972 |
Antitumor activity of cyclocytidine in a variety of tumors.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Line; Cyclization; Cyclophosphamide; Cytarabine; Cytidine; Dose-Response Relationship, Drug; Female; Fluorouracil; Leukemia L1210; Leukemia, Experimental; Male; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Sarcoma 180 | 1972 |
Studies on the antiphlogistic activity of cytostatics.
Topics: Animals; Anti-Inflammatory Agents; Antimetabolites; Carrageenan; Chloramphenicol; Cyclophosphamide; Dextrans; Edema; Fluorouracil; Foot; Hydrolysis; Indomethacin; Inflammation; Leukocyte Count; Male; Methotrexate; Penicillamine; Phenylbutazone; Rats; Triaziquone | 1972 |
The effect of operative treatment, chemotherapy, and oestrogens on the phagocytic activity of the reticuloendothelial system.
Topics: Aged; Antineoplastic Agents; Cyclophosphamide; Diethylstilbestrol; Estradiol; Fluorouracil; Half-Life; Humans; Methotrexate; Middle Aged; Mononuclear Phagocyte System; Neoplasms; Phagocytosis; Serum Albumin, Radio-Iodinated; Surgical Procedures, Operative | 1972 |
Inhibition of cell dcivision and denervation hypersensitivity in skeletal muscle.
Topics: Acetylcholine; Animals; Fluorouracil; Hindlimb; Methotrexate; Mitosis; Muscle Contraction; Muscle Denervation; Muscles; Rats; Receptors, Drug; Thymidine; Tritium; Vincristine | 1972 |
Use of mouse vaginal and rectal epithelium to screen antimitotic effects of systemically administered drugs.
Topics: Animals; Antineoplastic Agents; Cytarabine; Epithelial Cells; Epithelium; Female; Fluorouracil; Hydroxyurea; Mechlorethamine; Methotrexate; Mice; Mitosis; Podophyllin; Rectum; Vagina; Vinblastine | 1971 |
[Effect of cytostatics on thrombocyte aggregation].
Topics: Antineoplastic Agents; Blood Platelets; Fluorouracil; Humans; Methotrexate; Platelet Adhesiveness; Triaziquone; Vinblastine | 1971 |
Comments on morbidity in present-day radiotherapy.
Topics: Breast Neoplasms; Buttocks; Carcinoma, Squamous Cell; Dactinomycin; Erythema; Female; Fluorouracil; Hodgkin Disease; Humans; Laryngeal Neoplasms; Liver Cirrhosis; Methotrexate; Morbidity; Myelitis; Pharyngeal Neoplasms; Radiotherapy; Radiotherapy Dosage; Spinal Cord; Uterine Cervical Neoplasms; Xerostomia | 1971 |
Effective anti-cancer agents selected by suppression of cesium-131 uptake.
Topics: Adrenalectomy; Antineoplastic Agents; Breast Neoplasms; Cesium Isotopes; Cyclophosphamide; Estrogens; Fluorouracil; Hot Temperature; Humans; Intestinal Mucosa; Kidney; Liver; Methotrexate; Neoplasm Metastasis; Organ Size; Oxygen Consumption; Sarcoma; Spleen; Testosterone | 1971 |
Five-drug therapy for advanced breast cancer: a phase I study.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Vincristine | 1971 |
Multiple drug therapy for disseminated malignant tumours.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Child; Cyclophosphamide; Cytarabine; Dactinomycin; Drug Synergism; Female; Fluorouracil; Humans; Leukocyte Count; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms; Remission, Spontaneous; Urinary Bladder Neoplasms; Vincristine | 1971 |
Chemotherapy for metastatic colorectal liver carcinoma by intra-aortic infusion.
Topics: Antineoplastic Agents; Aorta, Abdominal; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Liver Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Rectal Neoplasms; Remission, Spontaneous; Retrospective Studies; Time Factors; Vinblastine; Vincristine | 1971 |
[Evaluation, in newborn Swiss mice, of the carcinogenic activity of some antineoplastic and immunosuppressive compounds].
Topics: Adenoma; Animals; Animals, Newborn; Antineoplastic Agents; Asparaginase; Azathioprine; Fluorouracil; Immunosuppressive Agents; Leukemia, Experimental; Leukemia, Lymphoid; Lung Neoplasms; Methotrexate; Mice; Neoplasms, Experimental | 1971 |
In vivo prediction of drug sensitivity with cancer-seeking isotopes.
Topics: Amides; Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma 256, Walker; Cyclophosphamide; Deoxyuridine; Diethylstilbestrol; Female; Fluorouracil; Fluoxymesterone; Humans; Imidazoles; Iodine Radioisotopes; Methotrexate; Neoplasms; Nitrosourea Compounds; Phosphates; Rats; Serum Albumin, Radio-Iodinated; Sodium Isotopes; Triazenes; Vincristine | 1971 |
[Intra-arterial chemotherapy in the treatment of pelvic tumors].
Topics: Angiography; Antineoplastic Agents; Catheterization; Fluorouracil; Humans; Injections, Intra-Arterial; Methods; Methotrexate; Pelvic Neoplasms; Thrombosis | 1971 |
Seventy-five cases of solid tumours treated by a modified quadruple chemotherapy regime.
Topics: Adolescent; Adult; Aged; Breast Neoplasms; Bronchial Neoplasms; Child; Cyclophosphamide; Female; Fluorouracil; Gastrointestinal Neoplasms; Head; Head and Neck Neoplasms; Humans; Infant; Injections, Intravenous; Male; Melanoma; Methotrexate; Middle Aged; Neoplasms; Ovarian Neoplasms; Sarcoma; Testicular Neoplasms; Uterine Cervical Neoplasms; Vincristine | 1971 |
Intra-arterial chemotherapy with surgery or radiotherapy in tumours of the head-neck region.
Topics: Fluorouracil; Head; Head and Neck Neoplasms; Injections, Intra-Arterial; Methotrexate; Neoplasms | 1971 |
[On the treatment of bronchopulmonary cancer with various methods of monochemotherapy and polychemotherapy].
Topics: Antineoplastic Agents; Bronchial Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Lung Neoplasms; Methotrexate | 1971 |
Embryonal cell carcinoma of the ovary. Report of a case.
Topics: Abdominal Neoplasms; Adolescent; Age Factors; Black People; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Recurrence, Local; Ovarian Neoplasms; Teratoma; Vincristine | 1971 |
[Role of chemotherapy in the treatment of primary bronchial carcinoma].
Topics: Antineoplastic Agents; Arabinose; Bronchial Neoplasms; Cyclophosphamide; Cytarabine; Fluorouracil; Humans; Methotrexate; Vinblastine | 1971 |
[Blood coagulation under chemotherapy of bronchial carcinoma].
Topics: Antineoplastic Agents; Blood Coagulation; Bronchial Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Methotrexate; Thromboplastin; Vinblastine | 1971 |
Association of cancer of the breast and acute myelocytic leukemia.
Topics: Adenocarcinoma; Adult; Aged; Anti-Bacterial Agents; Breast Neoplasms; Carcinoma; Female; Fluorouracil; Humans; Leukemia, Myeloid; Lymphatic Metastasis; Mastectomy; Mercaptopurine; Methotrexate; Middle Aged | 1967 |
Sequential biochemical alteration to antifolate resistance in L1210 leukaemia.
Topics: Animals; Biological Transport, Active; Cell Division; Cytogenetics; Drug Hypersensitivity; Fluorouracil; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Molecular Biology; Neoplasm Transplantation; Tetrahydrofolate Dehydrogenase; Tritium | 1967 |
Comparative sensitivity to various antimetabolites of several established cell lines derived from the buffy coat of normal humans and patients with neoplastic diseases.
Topics: Antimetabolites; Blood Cells; Cell Line; Culture Techniques; Cytarabine; Fluorouracil; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Mitosis; Neoplasms | 1969 |
Studies on the effects of hydroxyurea and other anticancer drugs upon pyrimidine metabolism.
Topics: Amidohydrolases; Animals; Antineoplastic Agents; Ascites; Carbon Isotopes; Cyclophosphamide; Cytarabine; Deoxyuridine; DNA; Fluorouracil; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Mice; Neoplasms, Experimental; Orotic Acid; Pyrimidines; Transferases; Triazines | 1969 |
The effect of methotrexate (amethopterin) on wound healing: an experimental study.
Topics: Animals; Cyclophosphamide; Fluorouracil; Leucovorin; Methotrexate; Neoplasms; Rats; Wound Healing | 1965 |
A portable pump ("conjector") for regional perfusion cancer chemotherapy.
Topics: Antineoplastic Agents; Blood Cell Count; Chemotherapy, Cancer, Regional Perfusion; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Neoplasms | 1966 |
Intra-arterial chemotherapy for recurrent neoplasms.
Topics: Adult; Aged; Catheterization; Female; Fluorouracil; Humans; Infusions, Parenteral; Injections, Intra-Arterial; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis | 1967 |
Historic and current intra-arterial chemotherapy.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Extremities; Female; Fluorouracil; Follow-Up Studies; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Mechlorethamine; Methotrexate; Neoplasms; Pelvic Neoplasms; Thoracic Neoplasms | 1970 |
Skin homograft survival in cancer chemotherapy patients.
Topics: Adult; Aged; Antineoplastic Agents; Carbamates; Female; Fluorouracil; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Mitomycins; Neoplasms; Skin Transplantation; Transplantation, Homologous; Urea | 1966 |
Suppression of murine leukemias by L-asparaginase. Incidence of sensitivity among leukemias of various types: comparative inhibitory activities of guinea pig serum L-asparaginase and Escherichia coli L-asparaginase.
Topics: Amidohydrolases; Animals; Antineoplastic Agents; Asparagine; Azaserine; Blood; Cyclophosphamide; Escherichia coli; Fluorouracil; Guinea Pigs; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Mitomycins; Prednisone; Vincristine | 1967 |
New approaches in administration of anticancer drugs.
Topics: Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Cytarabine; Female; Fluorouracil; Humans; Lung Neoplasms; Mercaptopurine; Methotrexate; Neoplasms; Prognosis; Time Factors | 1969 |
Malabsorption due to cytostatics.
Topics: Aminopterin; Animals; Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Humans; Intestinal Absorption; Intestinal Mucosa; Malabsorption Syndromes; Methotrexate | 1969 |
[Therapy of the metastasising bronchial cancer].
Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Bronchial Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Hydrazines; Male; Methotrexate; Neoplasm Metastasis; Radiography; Vinblastine | 1969 |
[Association of cytotoxic agents with radiotherapy: experimental bases and initial results in solid tumors].
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Synergism; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Methotrexate; Neoplasms; Respiratory Tract Neoplasms; Vinblastine | 1969 |
[Practical use of immunosuppressive and cytostatic drugs in dermatological diseases].
Topics: Antineoplastic Agents; Azathioprine; Condylomata Acuminata; Fluorouracil; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Papilloma; Pemphigus; Precancerous Conditions; Psoriasis; Scleroderma, Systemic; Skin Diseases; Skin Neoplasms; Virus Diseases | 1970 |
[Our experience with Vinca alkaloids in the poly-chemotherapy of inoperable bronchopulmonary cancer].
Topics: Alkylating Agents; Antineoplastic Agents; Bronchial Neoplasms; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Vinblastine | 1970 |
Combination chemotherapy of testicular tumors.
Topics: Adult; Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Humans; Male; Methotrexate; Teratoma; Testicular Neoplasms; Vincristine | 1970 |
Clinical immunologic responsiveness in malignant disease. I. Delayed hypersensitivity reaction and the effect of cytotoxic drugs.
Topics: Adolescent; Adult; Aged; Antigens; Antineoplastic Agents; Breast Neoplasms; Candida; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Hypersensitivity, Delayed; Immunosuppressive Agents; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mumps virus; Neoplasms; Nitrobenzenes; Ovarian Neoplasms; Skin Tests; Tuberculin; Uterine Cervical Neoplasms; Vinblastine | 1970 |
Local chemotherapy of cutaneous neoplasms.
Topics: Adenocarcinoma; Allergy and Immunology; Antineoplastic Agents; Carcinoma, Squamous Cell; Dactinomycin; Fibrosarcoma; Fluorouracil; Humans; Hypersensitivity; Leukemia; Lymphoma; Melanoma; Methotrexate; Nitrogen Mustard Compounds; Skin Neoplasms; Triaziquone | 1970 |
The effect of chemotherapy on germinal testicular tumors in mice.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Female; Fluorouracil; Male; Methotrexate; Mice; Neoplasm Transplantation; Teratoma; Testicular Neoplasms; Time Factors; Vincristine | 1970 |
[Treatment of dermatologic lesions using immunosuppressive agents and cytostatics].
Topics: Antineoplastic Agents; Azathioprine; Dermatomyositis; Fluorouracil; Humans; Immunosuppressive Agents; Methotrexate; Pemphigus; Psoriasis; Scleroderma, Systemic; Skin Diseases; Skin Neoplasms | 1970 |
Adverse effect of antitumor drugs on the prevention of metastasis in mice.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Fluorouracil; Male; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasm Metastasis; Vinblastine | 1970 |
[Experimental results of the use of polychemotherapy in malignant tumors].
Topics: Amides; Amputation, Surgical; Animals; Antineoplastic Agents; Benzoates; Carcinoma; Cyclophosphamide; Drug Synergism; Fluorouracil; Hydrazines; Methotrexate; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Neoplasms, Experimental; Vinblastine | 1970 |
[Polychemotherapeutic treatment of pulmonary neoplasms].
Topics: Carcinoma, Bronchogenic; Cyclophosphamide; Drug Synergism; Evaluation Studies as Topic; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Time Factors | 1970 |
Implications of biochemical, cytokinetic, pharmacologic, and toxicologic relationships in the design of optimal therapeutic schedules.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Disease Models, Animal; DNA, Neoplasm; Fluorouracil; Half-Life; Hydroxyurea; In Vitro Techniques; Kinetics; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Mitosis; Nitrosourea Compounds; Thiosemicarbazones | 1970 |
[On uptake of 5-FU, 6-MP and methotrexate by ehrlich ascites tumor cells in vitro].
Topics: Adenine; Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Fluorouracil; In Vitro Techniques; Male; Mercaptopurine; Methotrexate; Mice; Sulfur Isotopes; Time Factors; Tritium; Uracil | 1970 |
Specific binding of cortisol in subcellular fractions of HeLa cells: temperature dependence and effects of inhibitors.
Topics: 17-Hydroxycorticosteroids; Arsenicals; Azides; Binding Sites; Cell Nucleus; Chloramphenicol; Cyanides; Cycloheximide; Cytoplasm; Dactinomycin; Depression, Chemical; Dinitrophenols; Female; Fluorouracil; HeLa Cells; Hexoses; Humans; Hydrocortisone; In Vitro Techniques; Iodoacetates; Methotrexate; Microsomes; Mitochondria; Ouabain; Prednisolone; Puromycin; Temperature; Tritium | 1971 |
Chemotherapy of cancer of the gut.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Methotrexate; Mitomycins | 1971 |
Preferential attack on cancer following major cancer surgery.
Topics: Agar; Alkylating Agents; Antineoplastic Agents; Culture Techniques; DNA, Neoplasm; Fluorouracil; Humans; Mechlorethamine; Methods; Methotrexate; Neoplasms; Neoplastic Cells, Circulating; Radioisotopes; Sulfhydryl Compounds | 1971 |
[Further proposals for chemotherapeutic prophylaxis of recurrence of bronchial carcinoma].
Topics: Antibiotics, Antineoplastic; Bronchial Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Leukopenia; Methotrexate; Neoplasm Metastasis; Prognosis; Vinblastine | 1971 |
Further clinical studies of combination chemotherapy using cyclophosphamide, vincristine, methotrexate and 5-flourouracil in solid tumors.
Topics: Cyclophosphamide; Fluorouracil; Humans; Methotrexate; Neoplasms; Vincristine | 1971 |
Attempted chemotherapy of carcinoid tumour.
Topics: Carcinoid Tumor; Chlorambucil; Fluorouracil; Humans; Hydroxyindoleacetic Acid; Male; Methotrexate; Middle Aged; Serotonin | 1971 |
The relation of tumour size to the results of chemotherapy in malignant tumours.
Topics: Amputation, Surgical; Animals; Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Mercaptopurine; Methotrexate; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Procarbazine; Prognosis; Vinblastine | 1971 |
Drugs and their abuse no. V--misuse of cytotoxic drugs.
Topics: Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Humans; Leukemia; Mechlorethamine; Melphalan; Methotrexate; Substance-Related Disorders; Vinblastine; Vincristine | 1971 |
[The effect of various cytostatic drugs on the growth of 12 chosen mycobacterial strains].
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Busulfan; Chemical Phenomena; Chemistry; Culture Media; Drug Resistance, Microbial; Fluorouracil; Mercaptopurine; Methotrexate; Mitomycins; Mycobacterium; Species Specificity | 1971 |
Intravaginal and intrarectal screening of antimitotic drugs for topical effectiveness.
Topics: Animals; Antineoplastic Agents; Colchicine; Cytarabine; Daunorubicin; Evaluation Studies as Topic; Female; Fluorouracil; Hydroxyurea; Intestinal Mucosa; Mechlorethamine; Methods; Methotrexate; Mice; Mitosis; Mucous Membrane; Nitrosourea Compounds; Podophyllin; Rectum; Vagina; Vinblastine; Vincristine | 1971 |
The effect of anti-metabolites on leptazol induced fits in rats.
Topics: Animals; Antimetabolites; Azathioprine; Brain; Cytarabine; Daunorubicin; Fluorouracil; Folic Acid; Folic Acid Antagonists; Methotrexate; Pentylenetetrazole; Pyrimethamine; Rats; Seizures | 1971 |
[Combined cytostatic treatment of solid tumours with cyclophosphamide (Endoxan), vincristine, methylaminopterin (Methotrexate) and 5-fluorouracil].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Marrow; Child; Child, Preschool; Cyclophosphamide; Enteritis; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasms; Neuritis; Remission, Spontaneous; Stomatitis; Vincristine | 1971 |
[Indication for antineoplastic agents (using 3H-thymidine)].
Topics: Antineoplastic Agents; Culture Techniques; Depression, Chemical; DNA, Neoplasm; Fluorouracil; Humans; Methotrexate; Mitomycins; Stomach Neoplasms; Thymidine; Tritium; Vinblastine | 1971 |
[Combined chemotherapy of solid tumors].
Topics: Cyclophosphamide; Fluorouracil; Humans; Methotrexate; Neoplasms; Vincristine | 1971 |
Differential effects of anti-tumour drugs on human tumour and spleen DNA synthesis in vitro.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Culture Techniques; Disease Models, Animal; DNA; Fluorouracil; Melphalan; Methotrexate; Mice; Spleen | 1971 |
Effects of various drugs on insulin antibodies.
Topics: Animals; Antibodies; Antineoplastic Agents; Bromouracil; Chlorambucil; Chlorpropamide; Complement Fixation Tests; Cyclophosphamide; Dactinomycin; Diaphragm; Diethylstilbestrol; Drug Synergism; Female; Fluorouracil; Gonadal Steroid Hormones; Guinea Pigs; Hydrocortisone; Injections, Intraperitoneal; Injections, Subcutaneous; Insulin Antibodies; Male; Mercaptopurine; Methotrexate; Neutralization Tests; Phenformin; Testosterone; Tolbutamide; Triazines | 1971 |
Nonhormonal cancer chemotherapy and the vaginal smear.
Topics: Female; Fluorouracil; Humans; Methotrexate; Neoplasms; Vagina; Vaginal Smears | 1967 |
[Internal cancer therapy: cooperative clinical studies. Principles, organization and first results of the Swiss chemotherapy group].
Topics: Adenocarcinoma; Androgens; Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Bronchogenic; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Neoplasms; Switzerland | 1967 |
Sequential chemotherapy and radiation therapy of buccal mucosa carcinoma in South India. Methods and preliminary results.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cheek; Cobalt Isotopes; Deoxyuridine; Female; Fluorouracil; Folic Acid; Humans; India; Leukocyte Count; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Radioisotope Teletherapy; Radiotherapy Dosage | 1968 |
Further studies on selective cytotoxicity of triton WR-1339.
Topics: Clone Cells; Fluorouracil; Methotrexate; Neoplasms, Experimental; Prednisone; Surface-Active Agents | 1968 |
[Antitumor polychemotherapy].
Topics: Adult; Antimetabolites; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Chlorambucil; Cyclophosphamide; Drug Synergism; Female; Fluorouracil; Humans; Hydrazines; Hydroxyprogesterones; Injections, Intramuscular; Injections, Intravenous; Medroxyprogesterone; Methotrexate; Nitrogen Mustard Compounds; Ovarian Neoplasms; Progestins | 1968 |
[The results of attack polychemotherapy in broncho-pleuro-pulmonary cancer. Phytohemagglutinin in the prevention and treatment of hematologic complications of antimitotics].
Topics: Anemia, Aplastic; Antibiotics, Antineoplastic; Antineoplastic Agents; Azirines; Bronchial Neoplasms; Drug Synergism; Fluorouracil; Humans; Hydrazines; Injections, Intramuscular; Injections, Intravenous; Lectins; Lung Neoplasms; Mechlorethamine; Mercaptopurine; Methotrexate; Pleural Neoplasms; Vinblastine | 1968 |
[Trial polychemotherapy of inoperable cancer (apropos of 71 cases)].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Azirines; Bronchial Neoplasms; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Synergism; Fluorouracil; Humans; Hydrazines; Injections, Intravenous; Lung Neoplasms; Mechlorethamine; Mercaptopurine; Methotrexate; Neoplasm Metastasis; Pleural Neoplasms; Vinblastine | 1968 |
[Clinical trial of polychemotherapy of inoperable bronchopulmonary cancers].
Topics: Antineoplastic Agents; Azirines; Bronchial Neoplasms; Cyclophosphamide; Drug Synergism; Fluorouracil; Humans; Hydrazines; Injections, Intramuscular; Injections, Intravenous; Lung Neoplasms; Mercaptopurine; Methotrexate; Vinblastine | 1968 |
Antimetabolites in the treatment of skin disease.
Topics: Antimetabolites; Fluorouracil; Humans; Methotrexate; Skin Diseases; Skin Neoplasms | 1968 |
Methotrexate and the platelet count.
Topics: Antineoplastic Agents; Azathioprine; Blood Cell Count; Blood Platelets; Fluorouracil; Humans; Leukopenia; Methotrexate; Neoplasms; Thrombocytopenia; Thrombocytosis; Time Factors | 1968 |
[Polychemotherapy of bronchopulmonary cancer].
Topics: Antineoplastic Agents; Azirines; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Synergism; Fluorouracil; Humans; Hydrazines; Lung Neoplasms; Mercaptopurine; Mesothelioma; Methotrexate; Neoplasm Metastasis; Vinblastine | 1968 |
[Modalities and results of anticancer polychemotherapy in 73 cases of advanced broncho-pleuro-pulmonary cancer].
Topics: Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Drug Synergism; Female; Fluorouracil; Humans; Hydrazines; Injections, Intramuscular; Injections, Intravenous; Lung Neoplasms; Male; Mechlorethamine; Mercaptopurine; Methotrexate; Middle Aged; Vinblastine | 1968 |
A radioisotopic method for determining optimum non-surgical therapy for advanced cancer. II. Clinical experience.
Topics: Adenocarcinoma; Breast Neoplasms; Diethylstilbestrol; Female; Fluorouracil; Fluoxymesterone; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Male; Methods; Methotrexate; Neoplasm Metastasis; Phosphorus Isotopes; Prednisone | 1968 |
Intra-arterial infusion therapy for oral cancer.
Topics: Catheterization; Fluorouracil; Humans; Injections, Intra-Arterial; Methods; Methotrexate; Mouth Neoplasms | 1968 |
[218 cases of prolonged polychemotherapy in advanced cancer (especially bronchopulmonary). Modalities and results].
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Drug Synergism; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Hydrazines; Injections, Intramuscular; Injections, Intravenous; Lectins; Lung Neoplasms; Mechlorethamine; Mercaptopurine; Methotrexate; Mouth Neoplasms; Neoplasm Metastasis; Pharyngeal Neoplasms; Urogenital Neoplasms; Vinblastine | 1968 |
An ultrastructural study of the keratoacanthoma treated with methotrexate and 5-fluorouracil.
Topics: Animals; Cell Nucleus; Cytoplasm; Endoplasmic Reticulum; Fluorouracil; Keratoacanthoma; Male; Methotrexate; Microscopy, Electron; Rabbits; Ribosomes; Skin Neoplasms | 1968 |
A cell growth stimulating factor in partially hepatectomized rat serum.
Topics: Animals; Blood; Culture Techniques; Fluorouracil; Growth Substances; Hepatectomy; Liver Regeneration; Mercaptopurine; Methotrexate; Rats; Starvation | 1968 |
[Comparative quantitative studies of dye incorporation by Yoshida- and DS- carcinosarcoma-ascitic tumor cells as a contribution to the problem of natural resistance to cytostatic substances].
Topics: Animals; Antineoplastic Agents; Carcinosarcoma; Cell Membrane Permeability; Coloring Agents; Fluorouracil; Hydrazines; In Vitro Techniques; Mercaptopurine; Methotrexate; Photometry; Rats; Sarcoma, Experimental; Sarcoma, Yoshida; Triaziquone | 1968 |
[Basic differences in the effect of cellular parameters on the incorporation of strongly and weakly incorporated pharmaco].
Topics: Adsorption; Animals; Antineoplastic Agents; Binding Sites; Carcinosarcoma; Cell Membrane Permeability; Coloring Agents; Fluorouracil; Hydrazines; Methotrexate; Models, Biological; Rats; Receptors, Drug; Sarcoma, Experimental; Sarcoma, Yoshida; Triaziquone | 1968 |
Mechanism of pyrimethamine-induced megaloblastosis in human bone marrow.
Topics: Anemia, Macrocytic; Bone Marrow; Bone Marrow Diseases; Chorioretinitis; Culture Techniques; Deoxyuridine; DNA; Erythrocytes; Female; Fluorouracil; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Middle Aged; Nucleotides; Oxidation-Reduction; Pyrimethamine; Thymidine; Tritium | 1969 |
Dose-response curves for agents that impair cell reproductive integrity. A fundamental difference between dose-response curves of antimetabolites and those for radiation and alkylating agents.
Topics: Alkylating Agents; Animals; Antibody Formation; Antimetabolites; Cell Division; Cyclophosphamide; Fluorouracil; Immunization; Male; Mathematics; Melphalan; Methotrexate; Mice; Models, Biological; Nitrogen Mustard Compounds; Radiation Effects; Spleen; Thioguanine | 1969 |
Transplantable mouse plasma cell tumors in experimental chemotherapy.
Topics: Aniline Compounds; Animals; Antineoplastic Agents; Blood Protein Electrophoresis; Blood Proteins; Chlorambucil; Cyclophosphamide; Erythrocyte Count; Female; Fluorouracil; Hemoglobinometry; Humans; Leukocyte Count; Melphalan; Mercaptopurine; Methods; Methotrexate; Mice; Models, Biological; Mustard Compounds; Neoplasm Transplantation; Neoplasms, Experimental; Peritoneum; Plasma Cells; Plasmacytoma; Time Factors; Transplantation, Homologous; Triethylenemelamine | 1969 |
Response of normal calves to several cancer chemotherapeutic agents.
Topics: Animals; Blood Platelets; Cattle; Fluorouracil; Leukocyte Count; Mechlorethamine; Methotrexate; Uracil Mustard | 1969 |
[Arterial chemotherapy in granuloma gangraenescens].
Topics: Adult; Carotid Arteries; Female; Fluorouracil; Granuloma, Lethal Midline; Humans; Injections, Intra-Arterial; Methotrexate | 1965 |
Chemotherapy for liver cancer by protracted ambulatory infusion.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; Hepatic Artery; Humans; Infusions, Parenteral; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Rectal Neoplasms | 1965 |
Continuous preoperative intra-arterial perfusion of renal tumors with chemotherapeutic agents.
Topics: Catheterization; Fluorouracil; Humans; Kidney Neoplasms; Male; Methotrexate; Middle Aged; Nephrectomy; Perfusion | 1966 |
Growth of L1210 mouse leukemia cells in vitro.
Topics: Animals; Chromosomes; Culture Techniques; Fluorouracil; Folic Acid; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Microscopy | 1966 |
The antileukemic effectiveness of 5-fluorouracil and methotrexate in the combination chemotherapy of advanced leukemia L1210 in mice.
Topics: Animals; Antineoplastic Agents; Fluorouracil; Leukemia L1210; Methotrexate; Mice | 1966 |
Fate of amethopterin-resistant mutants in L1210 mouse leukemia populations.
Topics: Animals; Drug Hypersensitivity; Fluorouracil; In Vitro Techniques; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Tetrahydrofolate Dehydrogenase | 1966 |
Effects of some metabolic inhibitors on x-ray dose-response curves for the survival of mammalian cells in vitro, and on early recovery between fractionated x-ray doses.
Topics: Anti-Bacterial Agents; Culture Techniques; Cycloheximide; Dinitrophenols; Fluorouracil; HeLa Cells; Humans; Methotrexate; Puromycin; Radiation Effects; Radiometry | 1966 |
Comparative effects of DL-glyceraldehyde, 6-mercaptopurine, methotrexate and 5-fluorouracil on the Ehrlich ascites carcinoma in vivo.
Topics: Animals; Carcinoma, Ehrlich Tumor; Drug Synergism; Female; Fluorouracil; Glyceraldehyde; Mercaptopurine; Methotrexate; Mice | 1966 |
[Possible applications of antivitamins and antimetabolites in therapy].
Topics: Aminopterin; Antimetabolites; Azaserine; Child; Child, Preschool; Choriocarcinoma; Diazooxonorleucine; Female; Fluorouracil; Folic Acid Antagonists; Humans; Leukemia; Mercaptopurine; Methotrexate; Pregnancy; Pyrimethamine; Toxoplasmosis; Vitamin K; Vitamins | 1966 |
The role of ribonuclease in regression of lymphosarcoma P1798.
Topics: Animals; Chloromercuribenzoates; Chromatography; Corticosterone; Fluorouracil; Freezing; Hydrocortisone; In Vitro Techniques; Lymphocytes; Lymphoma, Non-Hodgkin; Methotrexate; Mice; Neoplasms, Experimental; Prednisolone; Ribonucleases; Vinblastine; Vincristine | 1966 |
Patient protection in cancer chemotherapy.
Topics: Adult; Anti-Bacterial Agents; Culture Media; Cyclophosphamide; Fluorouracil; Germ-Free Life; Humans; Leukemia; Leukopenia; Male; Mercaptopurine; Methotrexate; Prednisolone; Teratoma; Vincristine | 1966 |
Studies on eosinophil granulocytes. II. The effect of cytostatics on the uterine response to oestrogen.
Topics: Animals; Castration; Catalase; Chloramphenicol; Eosinophils; Estrogens; Female; Fluorouracil; Liver; Mercaptopurine; Methotrexate; Mice; Organ Size; Peroxidases; Pyridoxine; Streptomycin; Triazoles; Uterus | 1966 |
Intra-arterial chemotherapy in advanced pelvic tumors.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Pelvic Neoplasms; Rectal Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Vulvar Neoplasms | 1967 |
A model system for examining the action of anti-cancer agents at the cellular level in vivo.
Topics: Animals; Antineoplastic Agents; Azaserine; Cyclophosphamide; Dactinomycin; Fluorouracil; Hematopoiesis; Lymphoma; Mechlorethamine; Methotrexate; Mice; Models, Theoretical; Neoplasm Transplantation; Neoplasms, Experimental; Spleen; Thymidine; Tritium; Vinblastine | 1967 |
Disseminated melanoma. Biologic behavior and treatment.
Topics: Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Dactinomycin; Fluorouracil; Humans; Hydrazines; Hydroxyurea; Lymph Node Excision; Lymphatic Metastasis; Melanoma; Melphalan; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Perfusion; Vincristine | 1967 |
Chemical treatment of skin cancer.
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Colchicine; Fluorouracil; Humans; Methotrexate; Podophyllin; Skin Neoplasms; Triaziquone; Zinc | 1967 |
Studies of 6-N-hydroxylamino-9-beta-D-ribofuranosylpurine in mouse leukemia.
Topics: Adenine; Animals; Body Weight; Cytarabine; Drug Antagonism; Drug Synergism; Fluorouracil; Guanine; Leukemia; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Nucleosides; Phosphotransferases; Purines; Vincristine | 1967 |
Chemotherapy for the control of pain in inoperable cancer. A report of intra-arterial infusion in four patients.
Topics: Aged; Fluorouracil; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Neoplasms; Pain | 1967 |
[Attack treatment of broncho-pleuro-pulmonary cancer by polychemotherapy under the protection of phytohemagglutinin].
Topics: Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Azirines; Betamethasone; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Lectins; Lung Neoplasms; Male; Mechlorethamine; Mercaptopurine; Methotrexate; Middle Aged; Pleural Neoplasms; Sarcoma; Vinblastine | 1967 |
Effect of antimetabolites on kinetic behavior of proliferating cultured L1210 leukemia cells.
Topics: Animals; Antimetabolites; Azaserine; Cell Division; Culture Techniques; Cytarabine; Fluorouracil; Kinetics; Leukemia L1210; Mathematics; Methotrexate | 1967 |
Studies on drug transport by normal human leukocytes.
Topics: Amino Acids; Biological Transport; Biological Transport, Active; Fluorouracil; Humans; Leukocytes; Mercaptopurine; Methotrexate; Ribose; Thiourea | 1967 |
[Drug therapy in advanced squamous cell carcinoma of the ORL region].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Palliative Care; Prognosis | 1984 |
Combined radiotherapy and CMF-B cytotoxic regimen in stage III-IV head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging | 1984 |
[Chemotherapy of esophageal cancer].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Doxorubicin; Esophageal Neoplasms; Fluorouracil; Humans; Methotrexate; Vinca Alkaloids | 1984 |
[Clinical evaluation on the sensitivity test for anti-cancer agents in malignant bone and soft-tissue tumors].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Resistance; Fluorouracil; Histiocytoma, Benign Fibrous; Humans; Ifosfamide; Lymphoma; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Osteosarcoma; Sarcoma, Ewing; Soft Tissue Neoplasms; Succinate Dehydrogenase; Vincristine | 1984 |
Reevaluation of 5-fluorouracil as a single therapeutic agent for gestational trophoblastic neoplasms.
Topics: Choriocarcinoma; Diarrhea; Female; Fluorouracil; Follow-Up Studies; Humans; Hydatidiform Mole, Invasive; Mercaptopurine; Methotrexate; Neoplasm Recurrence, Local; Pregnancy; Uterine Neoplasms | 1984 |
Tamoxifen and conjugated estrogens (Premarin) followed by sequenced methotrexate and 5-FU in refractory advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Estrogens, Conjugated (USP); Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Tamoxifen | 1984 |
Adjuvant chemotherapy in breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Menopause; Methotrexate | 1983 |
Chemoendocrine versus endocrine therapy in breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Methotrexate; Prednisone; Receptors, Estrogen; Tamoxifen | 1984 |
In vitro chemotherapy testing of transitional cell carcinoma.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Transitional Cell; Cells, Cultured; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Fluorouracil; Humans; In Vitro Techniques; Methotrexate; Thiotepa; Urinary Bladder Neoplasms | 1980 |
Safe and effective combination chemotherapy for squamous cell carcinomas of the head and neck.
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrocortisone; Methotrexate; Vincristine | 1980 |
External carotid artery infusion with single-and multiple-drug regimens in the rat.
Topics: Animals; Antineoplastic Agents; Bleomycin; Body Weight; Carcinoma, Squamous Cell; Carotid Artery, External; Drug Therapy, Combination; Fluorouracil; Infusions, Intra-Arterial; Male; Methotrexate; Neoplasm Transplantation; Neoplasms, Experimental; Rats | 1980 |
Sequential use of endocrine therapy and chemotherapy for metastatic breast cancer: effects on survival.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Palliative Care; Prednisone; Time Factors; Vincristine | 1980 |
Combination chemotherapy for advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrocortisone; Leucovorin; Methotrexate; Middle Aged; Time Factors; Vincristine | 1980 |
Intra-arterial infusion of anticancer drugs: theoretic aspects of drug delivery and review of responses.
Topics: Antineoplastic Agents; Bleomycin; Blood Flow Velocity; Doxorubicin; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Parenteral; Injections, Intra-Arterial; Injections, Intravenous; Melphalan; Methotrexate; Models, Biological | 1980 |
Advanced recurrent squamous cell carcinoma of the head and neck. Results of a chemotherapeutic regimen with adriamycin, bleomycin, 5-fluorouracil, methotrextate, and vitamin A.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Doxorubicin; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Vitamin A | 1980 |
5-fluorouracil-methotrexate synergy: enhancement of 5-fluorodeoxyridylate binding to thymidylate synthase by dihydropteroylpolyglutamates.
Topics: Animals; Cell Survival; Drug Synergism; Floxuridine; Fluorouracil; Folic Acid; Leukemia L1210; Methotrexate; Methyltransferases; Polyglutamic Acid; Protein Binding; Pteroylpolyglutamic Acids; Thymidylate Synthase | 1980 |
[Chemotherapy of malignant solid tumors].
Topics: Bleomycin; Breast Neoplasms; Bronchial Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Kidney Neoplasms; Lomustine; Methotrexate; Neoplasm Metastasis; Neoplasms; Remission, Spontaneous; Sarcoma; Vincristine | 1980 |
The influence of methotrexate pretreatment on 5-fluorouracil metabolism in L1210 cells.
Topics: Animals; Biological Transport; Deoxyuridine; Fluorouracil; Kinetics; Leucovorin; Leukemia L1210; Methotrexate; Mice; Phosphoribosyl Pyrophosphate; Purines; RNA, Neoplasm | 1981 |
Combination chemotherapy for advanced cutaneous T-cell lymphomas.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hydrocortisone; Leucovorin; Lymph Nodes; Lymphoma; Male; Methotrexate; Middle Aged; Skin Neoplasms; T-Lymphocytes; Vincristine | 1980 |
Chemotherapy for head and neck cancer relapsing after radiotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Time Factors | 1981 |
Dermatologic changes after systemic cancer therapy.
Topics: Adult; Antineoplastic Agents; Bleomycin; Cyclophosphamide; Cytotoxins; Dactinomycin; Doxorubicin; Drug Eruptions; Female; Fluorouracil; Humans; Methotrexate; Pigmentation Disorders | 1981 |
Sequential combination chemotherapy of advanced head and neck carcinoma: re-evaluation of a highly effective regimen.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Doxorubicin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Leucovorin; Male; Mercaptopurine; Methotrexate; Middle Aged; Vincristine | 1981 |
Effects of cytostatic drugs on the transmembrane potential and surface charge of cultured cells.
Topics: Antineoplastic Agents; Bleomycin; Cell Line; Female; Fluorouracil; HeLa Cells; Humans; Ion Channels; Membrane Potentials; Methotrexate; Ovarian Neoplasms; Triaziquone; Vinblastine; Vincristine | 1981 |
Cellular mutations and drug resistance probed by herpes simplex virus.
Topics: Animals; Bleomycin; Carcinoma, Squamous Cell; Chlorocebus aethiops; Drug Resistance; Fibroblasts; Fluorescent Antibody Technique; Fluorouracil; Humans; Methotrexate; Mice; Mutation; Simplexvirus; Thioguanine; Uridine | 1981 |
The role of methotrexate and dihydrofolate polyglutamates in the enhancement of fluorouracil action by methotrexate.
Topics: Animals; Cell Line; Cell Survival; Drug Administration Schedule; Drug Therapy, Combination; Fluorodeoxyuridylate; Fluorouracil; Folic Acid; Folic Acid Antagonists; Leukemia L1210; Methotrexate; Mice; Polyglutamic Acid; Pteroylpolyglutamic Acids; Thymidylate Synthase | 1981 |
Combination chemotherapy for advanced bladder cancer.
Topics: Bleomycin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Urinary Bladder Neoplasms | 1982 |
Optimal schedule of methotrexate and 5-fluorouracil in human breast cancer.
Topics: Breast Neoplasms; Cell Line; Drug Administration Schedule; Drug Evaluation; Drug Interactions; Drug Synergism; Female; Fluorouracil; Humans; Hypoxanthines; Leucovorin; Leukopenia; Methotrexate; Nausea; Phosphoribosyl Pyrophosphate; Time Factors | 1982 |
Preliminary report on the effects of a four drug cytoxic protocol on wound healing in the rat.
Topics: Abdomen; Animals; Bleomycin; Body Weight; Drug Administration Schedule; Female; Fluorouracil; Injections, Intraperitoneal; Leucovorin; Methotrexate; Postoperative Period; Rats; Rats, Inbred Strains; Stomach; Vincristine; Wound Healing | 1981 |
[Growth of tumour-cell colonies from human solid tumours (author's transl)].
Topics: Carmustine; Cisplatin; Clone Cells; Doxorubicin; Drug Resistance; Fluorouracil; Humans; In Vitro Techniques; Interferons; Methods; Methotrexate; Neoplasms | 1982 |
[Chemotherapy of cervical cancer].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitolactol; Uterine Cervical Neoplasms; Vincristine | 1982 |
Intensive combination chemotherapy for cancer of the oral cavity.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukocyte Count; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Vincristine | 1983 |
Non-platinum-containing combination chemotherapy for stage III-IV head and neck squamous carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Mitomycin; Mitomycins; Neoplasm Recurrence, Local; Neoplasm Staging; Time Factors; Vincristine | 1983 |
[Asymptomatic electrocardiographic abnormalities during antiblastic chemotherapy].
Topics: Aged; Antineoplastic Agents; Arrhythmias, Cardiac; Breast Neoplasms; Cardiac Complexes, Premature; Cyclophosphamide; Electrocardiography; Esophageal Neoplasms; Female; Fluorouracil; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Stomach Neoplasms; Tamoxifen; Vincristine | 1983 |
Bleomycin infusion followed by cyclophosphamide, methotrexate, and 5-fluorouracil in advanced squamous carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Heart Diseases; Humans; Infusions, Parenteral; Lung Diseases; Male; Methotrexate; Middle Aged; Prognosis | 1984 |
Drug resistance in cancer.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Azacitidine; Cisplatin; Cytarabine; Drug Resistance; Fluorouracil; Humans; Methotrexate; Neoplasms | 1984 |
Thymidine enhancement of methotrexate and 5-fluorouracil toxicity in cultured human colon carcinoma.
Topics: Cells, Cultured; Colonic Neoplasms; Drug Interactions; Flow Cytometry; Fluorouracil; Humans; Kinetics; Methotrexate; RNA; Thymidine | 1984 |
[Platin-containing cytostatic combinations in the therapy of advanced gynecologic carcinomas].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Fallopian Tube Neoplasms; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms; Prognosis; Uterine Neoplasms | 1984 |
Correlation of intralesional in vivo chemotherapy of line 10 hepatoma with in vitro drug sensitivity.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cell Line; Cisplatin; Dactinomycin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Fluorouracil; Guinea Pigs; Liver Neoplasms, Experimental; Methotrexate; Neoplastic Stem Cells; Stem Cells; Vincristine | 1983 |
An active chemotherapy regimen for squamous cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Erythrocytes; Fluorouracil; Hematopoiesis; Humans; Kidney; Leucovorin; Lung Neoplasms; Male; Methotrexate; Middle Aged; Vinblastine | 1984 |
Chemotherapeutic agent permeability to normal brain and delivery to avian sarcoma virus-induced brain tumors in the rodent: observations on problems of drug delivery.
Topics: Animals; Antineoplastic Agents; Avian Sarcoma Viruses; Bleomycin; Blood-Brain Barrier; Brain; Brain Neoplasms; Cyclophosphamide; Fluorouracil; Glioma; Methotrexate; Osmosis; Rats; Rats, Inbred F344; Tumor Virus Infections | 1984 |
[A method of radiation and combined treatment in inoperable cancer of the pancreas].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Gamma Rays; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Palliative Care; Pancreatic Neoplasms; Radioisotope Teletherapy; Radiotherapy Dosage; Radiotherapy, High-Energy; Vincristine | 1984 |
Combination chemotherapy for the treatment of metastatic basal cell carcinoma of the scrotum. A case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Basal Cell; Cisplatin; Fluorouracil; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Scrotum | 1984 |
Clinical response to chemotherapy and hormone therapy as first treatment after therapeutic ovariectomy in advanced breast cancer patients.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Castration; Cyclophosphamide; Dexamethasone; Doxorubicin; Female; Fluorouracil; Hormones; Humans; Methotrexate; Methyltestosterone; Middle Aged; Neoplasms, Hormone-Dependent; Progestins; Tamoxifen; Testosterone; Vincristine | 1982 |
Inability of dimethyl sulfoxide and 5-fluorouracil to open the blood-brain barrier.
Topics: Animals; beta-N-Acetylhexosaminidases; Blood-Brain Barrier; Capillary Permeability; Carotid Arteries; Dimethyl Sulfoxide; Evans Blue; Female; Fluorouracil; Hexosaminidase A; Hexosaminidases; Injections, Intra-Arterial; Methotrexate; Rats; Rats, Inbred Strains | 1983 |
Enhancement of the incorporation of 5-fluorodeoxyuridylate into DNA of HL-60 cells by metabolic modulations.
Topics: Cell Line; Deoxyuracil Nucleotides; DNA Replication; DNA, Neoplasm; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Kinetics; Leukemia, Myeloid, Acute; Methotrexate; Thymidine; Tritium | 1983 |
Intra-arterial infusion in tumors of the pelvis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Floxuridine; Fluorouracil; Humans; Iliac Artery; Infusions, Intra-Arterial; Leucovorin; Male; Melanoma; Methotrexate; Middle Aged; Ovarian Neoplasms; Pelvic Neoplasms; Prostatic Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms | 1983 |
Renal complications of cytotoxic therapy.
Topics: Animals; Antineoplastic Agents; Asparaginase; Cisplatin; Cyclophosphamide; Cytarabine; Dogs; Fluorouracil; Humans; Kidney Diseases; Methotrexate; Mitomycins; Neoplasms; Nitrosourea Compounds; Plicamycin; Procarbazine; Streptozocin; Syndrome | 1983 |
Aggressive combined modality therapy for advanced local-regional breast carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiomegaly; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Fluorouracil; Follow-Up Studies; Heart Failure; Humans; Mastectomy; Methotrexate; Middle Aged; Pilot Projects; Prednisone; Prospective Studies | 1984 |
Combination chemotherapy of metastatic breast carcinoma with cyclophosphamide, adriamycin, and peptichemio.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Drug Eruptions; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Nausea; Peptichemio; Phlebitis; Thiotepa; Time Factors; Vomiting | 1984 |
Rate-limiting steps in the interactions of fluoropyrimidines and methotrexate.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Drug Interactions; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Methotrexate; Mice; Neoplasm Proteins; RNA, Neoplasm; Thymidine Monophosphate | 1984 |
Drug effects on certain enzymes of carbohydrate metabolism in MCF-7 cells in culture.
Topics: Antineoplastic Agents; Breast Neoplasms; Cells, Cultured; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Glycerolphosphate Dehydrogenase; Humans; Methotrexate; Phosphofructokinase-1; Phosphogluconate Dehydrogenase; Tamoxifen | 1984 |
The abdominoinguinal incision in limb salvage and resection of pelvic tumors.
Topics: Abdominal Muscles; Abdominal Neoplasms; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; General Surgery; Humans; Inguinal Canal; Male; Methotrexate; Middle Aged; Pelvic Neoplasms | 1984 |
Changes of blood T cell subsets in patients receiving postoperative adjuvant chemotherapy for breast cancer.
Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory | 1984 |
[Non-hematologic adverse effects of cytostatic drugs].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Diarrhea; Drug Eruptions; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasms; Nervous System Diseases; Vomiting | 1984 |
Modulation of fluoropyrimidine cytotoxicity by methotrexate or 5-methyltetrahydrofolate in human leukemia cells in vitro.
Topics: Cells, Cultured; Drug Synergism; Floxuridine; Fluorouracil; Humans; Leukemia; Methotrexate; Tetrahydrofolates | 1984 |
Chemotherapy for adenocystic carcinoma.
Topics: Alkylating Agents; Antineoplastic Agents; Carcinoma, Adenoid Cystic; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Time Factors; Vinca Alkaloids | 1980 |
[Combined chemotherapy of bronchial carcinomas (author's transl)].
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Middle Aged; Vinblastine | 1980 |
Fulminant lung metastases from cancer of the breast.
Topics: Adult; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cyclophosphamide; Female; Fluorouracil; Humans; Immune Tolerance; Immunity, Cellular; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Prednisone; Respiratory Insufficiency; Vincristine | 1981 |
Adjuvant radiation therapy compared with cyclic chemotherapy in patients with mammary carcinoma. II. Changes of mitogen responses of blood lymphocytes.
Topics: Adult; Aged; Breast Neoplasms; Chlorambucil; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphocyte Activation; Methotrexate; Middle Aged; Phytohemagglutinins; Postoperative Period; Tuberculin | 1981 |
Experimental combination and single-agent chemotherapy in human lung-tumour xenografts.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lomustine; Lung Neoplasms; Methotrexate; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Neoplasms, Experimental; Procarbazine; Transplantation, Heterologous; Vincristine | 1982 |
The influence of radiation therapy quality control on survival, response and sites of relapse in oat cell carcinoma of the lung: preliminary report of a Southwest Oncology Group study.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Follow-Up Studies; Humans; Lung Neoplasms; Methotrexate; Quality Control; Vincristine | 1982 |
A phase II trial of tamoxifen, premarin, methotrexate and 5-fluorouracil in metastatic breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Drug Evaluation; Drug Therapy, Combination; Estrogens, Conjugated (USP); Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Receptors, Estrogen; Tamoxifen | 1982 |
[Bone metastasis of breast cancer. Apropos of a series of 50 cases].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; France; Humans; Methotrexate; Vincristine | 1982 |
Prognostic significance of hormone receptors in early recurrence of breast cancer.
Topics: Adenocarcinoma; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Receptors, Cell Surface; Retrospective Studies; Time Factors | 1983 |
Methotrexate and 5-fluorouracil following tamoxifen and premarin in advanced breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Breast Neoplasms; Drug Evaluation; Drug Therapy, Combination; Estrogens, Conjugated (USP); Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Receptors, Estrogen; Tamoxifen | 1983 |
[Chemotherapy of small cell carcinomas of the lung].
Topics: Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Prognosis; Retrospective Studies; Vinblastine; Vincristine | 1983 |
[Treatment of advanced ovarian cancer].
Topics: Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Prognosis | 1984 |
Sequential methotrexate and 5-fluorouracil: improved response rate in metastatic colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Colonic Neoplasms; Drug Administration Schedule; Drug Eruptions; Drug Evaluation; Drug Synergism; Female; Fluorouracil; Humans; Leukopenia; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Peripheral Nervous System Diseases; Rectal Neoplasms | 1984 |
Immunosuppression by cytostatic drugs?
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dacarbazine; Doxorubicin; Female; Fluorouracil; Ifosfamide; Immunization, Secondary; Immunosuppressive Agents; Mercaptopurine; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Procarbazine; T-Lymphocytes; Vinblastine; Vincristine | 1984 |
[Chemotherapy of metastasizing stomach cancer].
Topics: Doxorubicin; Fluorouracil; Humans; Leucovorin; Methotrexate; Stomach Neoplasms | 1984 |
Microcolony survival assay for jejunal crypt cells exposed to radiation alone and combined with cancer chemotherapeutic agents--methodological problems.
Topics: Animals; Antineoplastic Agents; Cell Survival; Cyclophosphamide; Dose-Response Relationship, Radiation; Fluorouracil; Injections, Intraperitoneal; Jejunum; Male; Methotrexate; Mice; Whole-Body Irradiation | 1983 |
[Pharmacokinetics of 5-fluorouracil and its permeation in pleural effusions in the therapy of metastatic breast cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Breast Neoplasms; Chromatography, High Pressure Liquid; Cyclophosphamide; Female; Fluorouracil; Humans; Kinetics; Metabolic Clearance Rate; Methotrexate; Middle Aged; Pleural Effusion; Pleural Neoplasms | 1984 |
Treatment of rat nephrotoxic nephritis. Use of 5-fluorouracil or methotrexate-5-fluorouracil association.
Topics: Animals; Drug Therapy, Combination; Fluorescent Antibody Technique; Fluorouracil; Glomerulonephritis; Kidney; Kidney Function Tests; Male; Methotrexate; Rats; Rats, Inbred Strains | 1984 |
The effect of adjuvant chemotherapy on cosmesis and complications in patients with breast cancer treated by definitive irradiation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arm; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Edema; Female; Fluorouracil; Humans; Methotrexate; Prednisone; Radiotherapy, High-Energy | 1983 |
[Chemotherapy of epithelial ovarian carcinoma].
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chlorambucil; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms | 1983 |
Treatment of metastatic colorectal carcinoma with 5-FU, mitomycin, vincristine, and methotrexate.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasm Metastasis; Rectal Neoplasms; Thrombocytopenia; Vincristine | 1984 |
Effects of cytotoxic drugs on proliferative vitreoretinopathy in the rabbit cell injection model.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Doxorubicin; Eye Diseases; Female; Fibroblasts; Fluorouracil; Male; Methotrexate; Rabbits; Retinal Detachment; Retinal Diseases; Triamcinolone; Trifluridine; Vitreous Body | 1984 |
Impact of adjuvant chemotherapy on cosmesis and complications in stages I and II carcinoma of the breast treated by biopsy and radiation therapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Breast Diseases; Breast Neoplasms; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Radiotherapy, High-Energy; Skin Diseases | 1984 |
Effect of antineoplastic agents on gamma-interferon production in human peripheral blood mononuclear cells.
Topics: Antineoplastic Agents; DNA Replication; Doxorubicin; Fluorouracil; Humans; Hydrocortisone; Interferon-gamma; Interleukin-2; Kinetics; Mercaptopurine; Methotrexate; Monocytes; Vincristine | 1984 |
[10 years' use of ftorafur in tumor chemotherapy at the Robert Rössle Institute. A retrospective analysis from the clinical-toxologic point of view].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Lomustine; Male; Methotrexate; Middle Aged; Neoplasms; Retrospective Studies; Tamoxifen; Tegafur; Vinblastine; Vincristine | 1984 |
The chemotherapy of granulosa cell tumors of the ovary: experience of the Wisconsin Clinical Cancer Center.
Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Granulosa Cell Tumor; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Prednisone; Retrospective Studies; Vincristine | 1984 |
Combined effects of methotrexate and 5-fluoropyrimidine on human breast cancer cells in serum-free culture.
Topics: Breast Neoplasms; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Floxuridine; Fluorouracil; Humans; Methotrexate | 1980 |
Effects of combination chemotherapy on immunoregulatory cells in peripheral blood of solid tumor cancer patients: correlation with rebound overshoot immune function recovery.
Topics: Adult; Aged; Altretamine; Antineoplastic Agents; Cell Adhesion; Drug Therapy, Combination; Fluorouracil; Humans; Immunity, Cellular; Indomethacin; Leucovorin; Lymphocyte Activation; Methotrexate; Middle Aged; Mitomycins; Monocytes; Neoplasms; Phytohemagglutinins; T-Lymphocytes, Regulatory; Time Factors | 1981 |
Immunologic monitoring in breast cancer patients receiving postoperative adjuvant chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Female; Fluorouracil; Humans; Immunity; Immunoglobulin M; Leukocyte Count; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Mastectomy; Methotrexate; Middle Aged; Rosette Formation | 1981 |
[Simultaneous combined radio-/chemotherapy of locally recurring breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cobalt Radioisotopes; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Radioisotope Teletherapy; Radiotherapy Dosage; Vincristine | 1984 |
[Adriablastin (doxorubicin) in the combined chemotherapy of patients with disseminated forms of breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Skin Neoplasms; Time Factors | 1984 |
Treatment of advanced breast cancer with aminoglutethimide--response after previous tamoxifen treatment.
Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Fluoxymesterone; Humans; Menopause; Methotrexate; Tamoxifen; Time Factors | 1984 |
The role of chemotherapy in untreated squamous-cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies | 1984 |
[Low-dose methotrexate and sequential 5-FU treatment in advanced gastric cancer].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 1984 |
Cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy in women more than 65 years old with advanced breast cancer: the elimination of age trends in toxicity by using doses based on creatinine clearance.
Topics: Aged; Aging; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Creatinine; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate | 1984 |
[Individualization of polychemotherapy for stage III breast cancer based on immunologic status].
Topics: Adult; Aged; Antibody Formation; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Immunity, Cellular; Levamisole; Lymphocyte Activation; Methotrexate; Middle Aged; Prednisolone; Prognosis; Vincristine | 1984 |
Sequential methotrexate and 5-FU in breast cancer resistant to the conventional application of these drugs.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis | 1984 |
Recall of UVB-induced erythema in breast cancer patient receiving multiple drug chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Erythema; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Photosensitivity Disorders; Ultraviolet Rays | 1984 |
Adjuvant chemoimmunotherapy with LMF + BCG in node-negative and node-positive breast cancer: 8 year results.
Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Chlorambucil; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Neoplasm Staging; Prognosis | 1984 |
Sequential combination chemotherapy with methotrexate and 5-fluorouracil in advanced colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Rectal Neoplasms | 1984 |
Abnormal deoxyuridine suppression as a rapid predictor for antimetabolite chemosensitivity: correlation with in vitro tests of growth inhibition.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Division; Cell Line; Colony-Forming Units Assay; Deoxyuridine; DNA; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Leukemia L1210; Methotrexate; Mice; Ovarian Neoplasms; Tumor Stem Cell Assay | 1984 |
New possibilities of cytostatic drug testing on patient tumor cells by flow cytometry.
Topics: Antineoplastic Agents; Ascitic Fluid; Cell Survival; Cells, Cultured; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Evaluation, Preclinical; Esterases; Female; Flow Cytometry; Fluorouracil; Humans; Hydrogen-Ion Concentration; Inflammation; Methotrexate; Neoplastic Stem Cells; Ovarian Neoplasms; Pleural Effusion; Uterine Cervical Neoplasms; Vinblastine; Vindesine | 1984 |
The use of human cancer cell lines as a primary screening system for antineoplastic compounds.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line; Cell Survival; Colonic Neoplasms; Cytarabine; Drug Evaluation, Preclinical; Drug Resistance; Female; Fluorouracil; Humans; Leukemia; Methotrexate; Neoplasms | 1984 |
Timed sequential chemotherapy following drug-induced kinetic recruitment in refractory ovarian cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Ascites; Cell Division; Doxorubicin; Female; Fluorouracil; Humans; Ifosfamide; Leukocyte Count; Methotrexate; Middle Aged; Ovarian Neoplasms; Time Factors | 1984 |
Identification of synergistic combinations of spirogermanium with 5-fluorouracil or cisplatin using a range of human tumour cell lines in vitro.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line; Cell Survival; Cisplatin; Colony-Forming Units Assay; Doxorubicin; Drug Synergism; Fluorouracil; Germanium; Humans; Methotrexate; Organometallic Compounds; Spiro Compounds; Tumor Stem Cell Assay | 1984 |
Carminomycin. A new anthracycline analog in the treatment of advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carubicin; Cyclophosphamide; Daunorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Myeloproliferative Disorders; Prednisone; Time Factors; Vincristine | 1984 |
The effect of postoperative and primary radiation therapy on delivered dose of adjuvant cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) chemotherapy in breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Leukocyte Count; Methotrexate; Probability; Retrospective Studies | 1984 |
Chemotherapy of advanced breast cancer. A general survey.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prednisone; Vincristine | 1984 |
Comparison of melphalan with cyclophosphamide, methotrexate, and 5-fluorouracil in patients with ovarian cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Ovarian Neoplasms; Probability; Random Allocation; Time Factors | 1984 |
[Systemic chemotherapy of mammary carcinoma: plasma and tissue concentrations of 5-fluorouracil and adriamycin, and result of CAF and CMF therapy of breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate | 1984 |
Adriamycin, dibromodulcitol, and mitomycin combination chemotherapy for patients with metastatic breast carcinoma previously treated with cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, and prednisone.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Middle Aged; Mitolactol; Mitomycins; Nausea; Prednisone; Soft Tissue Neoplasms; Thrombocytopenia; Time Factors; Vincristine; Vomiting | 1984 |
[Adjuvant chemo and hormone therapy in breast cancer].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Hormones; Humans; Mastectomy; Methotrexate; Postoperative Care | 1984 |
Relationship between estrogen receptors and CMF adjuvant chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Menopause; Methotrexate; Prognosis; Receptors, Estrogen; Tamoxifen | 1984 |
Sequential methotrexate and 5-FU in CMFP (cyclophosphamide, methotrexate, 5-FU, and prednisone) therapy for breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Hematologic Diseases; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Prednisone; Recurrence | 1984 |
Cyclophosphamide, methotrexate, and 5-FU (CMF)-induced nausea and vomiting: a controlled study with high-dose metoclopramide.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Metoclopramide; Middle Aged; Nausea; Random Allocation; Time Factors | 1984 |
[Use of adriamycin in the treatment of metastatic breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Castration; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lung Neoplasms; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Time Factors | 1984 |
Increased incidence of thromboembolism in stage IV breast cancer patients treated with a five-drug chemotherapy regimen. A study of 159 patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Coagulation Tests; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Prednisone; Thromboembolism; Vincristine | 1984 |
Breast cancer today.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Estrogens; Female; Fluorouracil; Humans; Methotrexate; Middle Aged | 1984 |
[Cytostatic therapy in metastatic breast cancer].
Topics: Anthraquinones; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Menopause; Methotrexate; Mitoxantrone; Prednisone; Vincristine | 1984 |
[Experimental toxicologic and therapeutic studies on the activity of the CMF(cyclophosphamide-methotrexate-5-fluorouracil) scheme versus the VMF(vincristine-methotrexate-5-fluorouracil) scheme].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma 256, Walker; Cyclophosphamide; Female; Fluorouracil; Male; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Sarcoma, Yoshida; Vincristine | 1984 |
The management of locally advanced breast cancer: a combined modality approach.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Receptors, Estrogen | 1984 |
Phase II study of mitolactol in chemotherapy-refractory metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitolactol; Neoplasm Metastasis; Receptors, Estrogen | 1984 |
[5 years' results of a CMF protocol (methotrexate, cyclophosphamide, fluorouracil) of adjuvant chemotherapy in breast cancers].
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Prognosis | 1984 |
Ludwig Breast Cancer trials LBCS III and IV: adjuvant endocrine treatment in postmenopausal patients.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Castration; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Hysterectomy; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1984 |
CMF adjuvant programs at the Milan Cancer Institute.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis | 1984 |
Prognostic value of various immunological tests in breast cancer patients treated with adjuvant postoperative chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Eosinophils; Female; Fluorouracil; Humans; Leukocyte Count; Methotrexate; Middle Aged; Postoperative Care; Prognosis | 1984 |
[Sequential combination chemotherapy in metastatic cancer of the breast].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Menopause; Methotrexate; Neoplasm Metastasis | 1984 |
[Initial therapeutic evaluations of 141 patients with carcinoma of the breast under 40 years of age].
Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Prognosis; Retrospective Studies | 1984 |
[Correlations between PRL and 17-beta-E in human breast cancer].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Estradiol; Female; Fluorouracil; Humans; Luteal Phase; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Ovariectomy; Postoperative Period; Prognosis; Prolactin | 1984 |
Quality of life for breast cancer patients receiving adjuvant chemotherapy.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Interpersonal Relations; Life Style; Methotrexate; Quality of Life | 1983 |
[5 years' experiences with adjuvant chemotherapy in primary breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Neoplasm Staging; Prognosis | 1984 |
Murine L5178Y cells resulting in altered drug sensitivities from fractionated radiation exposure in vitro.
Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Etoposide; Fluorouracil; Hydroxyurea; Leukemia L5178; Leukemia, Experimental; Methotrexate; Mice; Vincristine | 1984 |
Methotrexate and 5-fluorouracil in head and neck cancer.
Topics: Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Endoscopy; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Lymphatic Metastasis; Methotrexate; Neoplasm Staging | 1983 |
High-dose MTX/5-FU and adriamycin for gastric cancer.
Topics: Adult; Aged; Ambulatory Care; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Probability; Stomach Neoplasms; Time Factors | 1983 |
MTX/5-FU trials in gastrointestinal and other cancers.
Topics: Aged; Anemia; Conjunctivitis; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Humans; Intestinal Obstruction; Leucovorin; Methotrexate; Pancytopenia; Probability; Stomatitis | 1983 |
Sequential methotrexate-5-fluorouracil treatment of squamous cell carcinoma of the head and neck.
Topics: Carcinoma, Squamous Cell; Drug Therapy, Combination; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1983 |
Improved therapeutic index with sequential N-phosphonacetyl-L-aspartate plus high-dose methotrexate plus high-dose 5-fluorouracil and appropriate rescue.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Drug Therapy, Combination; Female; Fluorouracil; Leucovorin; Male; Methotrexate; Mice; Neoplasms; Organophosphorus Compounds; Phosphonoacetic Acid; Uridine | 1983 |
Combination chemotherapy for metastatic breast cancer with fluorouracil, adriamycin, cyclophosphamide, and methotrexate.
Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leucovorin; Methotrexate; Nausea; Neutropenia; Stomatitis; Vomiting | 1984 |
Psychosocial implications of adjuvant chemotherapy. A two-year follow-up.
Topics: Antineoplastic Combined Chemotherapy Protocols; Attitude; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Neoplasm Recurrence, Local; Quality of Life | 1983 |
Critical modulation by thymidine and hypoxanthine of sequential methotrexate-5-fluorouracil synergism in murine L1210 cells.
Topics: Animals; Cell Survival; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Hypoxanthine; Hypoxanthines; Kinetics; Leukemia L1210; Methotrexate; Mice; Thymidine | 1983 |
Tamoxifen and 5-fluorouracil in breast cancer: cytotoxic synergism in vitro.
Topics: Breast Neoplasms; Cell Line; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Estradiol; Female; Fluorouracil; Humans; Methotrexate; Receptors, Estradiol; Receptors, Estrogen; Tamoxifen | 1983 |
[Efficacy of doxorubicin (adriamycin) in disseminated forms of breast cancer].
Topics: Adult; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Time Factors; Vincristine | 1983 |
[Chemotherapy of metastasizing breast cancer. Adriamycin mono and combination therapy after LMFP pretreatment].
Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Prednisone; Thrombocytopenia; Vincristine | 1983 |
Kinetics of methotrexate, dacarbazine and 5-fluorouracil during isolated liver perfusion.
Topics: Animals; Biotransformation; Chemotherapy, Cancer, Regional Perfusion; Dacarbazine; Dogs; Dose-Response Relationship, Drug; Fluorouracil; Kinetics; Liver Neoplasms; Methotrexate | 1983 |
First experimental and clinical results of isolated liver perfusion with cytotoxics in metastases from colorectal primary.
Topics: Animals; Antineoplastic Agents; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Dacarbazine; Dogs; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Rectal Neoplasms | 1983 |
Effects on metastases of drug therapy during developing and established tumor immunity.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Fluorouracil; Immunity, Innate; Immunosuppression Therapy; Lung Neoplasms; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Transplantation Immunology | 1983 |
The treatment of primary operable transitional cell cancer of the bladder without cystectomy. Preliminary report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Urinary Bladder Neoplasms; Vincristine | 1983 |
Prevention of experimental massive peri-retinal proliferation by 5-fluoro-uracil.
Topics: Animals; Fibroblasts; Fluorouracil; Humans; Methotrexate; Rabbits; Retinal Detachment; Vitreous Body | 1983 |
Twenty-four hour combination chemotherapy: a feasibility study with implications for improved adjuvant treatment of breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Feasibility Studies; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Time Factors; Vincristine | 1983 |
Assessment of antimetabolite cytotoxicity: a comparison of clonogenic assays and tritiated deoxyuridine incorporation.
Topics: Animals; Cell Cycle; Cell Line; Cell Survival; Clone Cells; Cytarabine; Deoxyuridine; Dose-Response Relationship, Drug; Fluorouracil; Humans; Leukemia L1210; Melanoma; Methotrexate; Mice; Tritium | 1983 |
Results of combined treatment of patients with locally advanced breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Mastectomy; Mastitis; Methotrexate; Pregnancy; Radiotherapy Dosage; Vincristine | 1983 |
Ultrastructural changes in the dog liver cell after isolated liver perfusion with various cytotoxins.
Topics: Animals; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Dacarbazine; Dogs; Dose-Response Relationship, Drug; Fluorouracil; Liver; Liver Neoplasms; Methotrexate; Microscopy, Electron | 1983 |
Effect of combined chemotherapy tested in partially hepatectomized rats bearing Zajdela hepatoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; DNA; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Fluorouracil; Hepatectomy; Liver Neoplasms, Experimental; Liver Regeneration; Methotrexate; Rats; Rats, Inbred Strains | 1983 |
[Ovarian carcinoma: surgery and polychemotherapy with cisplatin. Considerations on a clinical case].
Topics: Carcinoma; Cisplatin; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms | 1983 |
Multimodal treatment of locoregionally advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis | 1983 |
Endocrine consequences of CMF adjuvant therapy in premenopausal and postmenopausal breast cancer patients.
Topics: Adrenal Glands; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Endocrine Glands; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Ovary; Pituitary Gland | 1983 |
Multimodality therapy of stage III adenocarcinoma of the breast.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Node Excision; Mastectomy; Methotrexate; Middle Aged; Neoplasm Staging; Pilot Projects; Radiotherapy; Receptors, Estrogen | 1983 |
[CMF (cyclophosphamide, methotrexate, ftorafur) chemotherapy in advanced breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged | 1983 |
Adjuvant chemotherapy (CMF) for breast carcinoma. Patient's compliance and total dose achieved.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukopenia; Menopause; Methotrexate; Middle Aged; Patient Compliance | 1983 |
Prolonged remissions of metastatic breast cancer achieved with a six-drug regimen of relatively low toxicity.
Topics: Adult; Aged; Alopecia; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Heartburn; Humans; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Time Factors; Vincristine | 1983 |
The effect of postoperative radiotherapy on the feasibility of optimal dose adjuvant CMF chemotherapy in stage II breast carcinoma.
Topics: Actuarial Analysis; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Mastectomy; Menopause; Methotrexate; Postoperative Period; Retrospective Studies | 1983 |
[Survival and factors related to the survival of recurrent breast cancer patients--a study with quantification theory].
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Tamoxifen | 1983 |
Comment on "The methodologic dilemma in retrospectively correlating the amount of chemotherapy received in adjuvant therapy protocols with disease-free survival".
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Methotrexate; Prognosis; Retrospective Studies | 1983 |
Multimodal therapy in the treatment of breast cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukocyte Count; Methotrexate; Prednisone; Prognosis; Radiotherapy Dosage; Retrospective Studies; Vincristine | 1983 |
[Bone scintigraphy in mastectomized patients with and without chemotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Middle Aged; Radionuclide Imaging; Vincristine | 1983 |
[Comparative evaluation of the results of mono- and polychemotherapy of disseminated forms of breast cancer using the CMFVP program and anthracycline antibiotics (carminomycin and adriamycin)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carubicin; Cyclophosphamide; Daunorubicin; Doxorubicin; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prednisone; Vincristine | 1983 |
Oral and pharyngeal cancer: combined approach for multimodal therapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cobalt Radioisotopes; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Iridium; Lymph Node Excision; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Staging; Pharyngeal Neoplasms; Radioisotopes; Time Factors | 1983 |
Study on the comparability of 6 versus 12 cycles of adjuvant cyclophosphamide, methotrexate, and fluorouracil.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate | 1983 |
Prognostic factors in primary breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1983 |
Combination of anticancer agents with folic acid in the treatment of murine leukaemia P388.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation, Preclinical; Drug Synergism; Fluorouracil; Folic Acid; Leukemia P388; Leukemia, Experimental; Methotrexate; Mice; Mitomycins | 1984 |
Interactions of radiation and 5-fluorouracil, cyclophosphamide or methotrexate in intestinal crypt cells.
Topics: Animals; Cell Survival; Cyclophosphamide; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Fluorouracil; Intestinal Mucosa; Jejunum; Male; Methotrexate; Mice | 1984 |
Studies of variation in inherent sensitivities to radiation, 5-fluorouracil and methotrexate in a series of human and murine tumor cell lines in vitro.
Topics: Animals; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Tolerance; Fluorouracil; Humans; Methotrexate; Mice; Radiation Tolerance | 1984 |
Sequential methotrexate plus 5-FU in advanced breast and colorectal cancers: a phase II study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Rectal Neoplasms | 1984 |
Antiestrogen-cytotoxic chemotherapy and bacillus Calmette-Guerin vaccination in stage II breast cancer: seventy-two-month follow-up.
Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Estrogen Antagonists; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Prospective Studies; Random Allocation; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1984 |
The design of rational combination chemotherapy for cancer.
Topics: Antineoplastic Agents; Drug Interactions; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Neoplasms | 1984 |
[Surgical method and combination chemotherapy in treating stage-III and IV ovarian cancer].
Topics: Altretamine; Antineoplastic Agents; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms; Ovary; Postoperative Care; Tegafur; Time Factors | 1980 |
[Breast neoplasms. Progress by means of adjuvant chemotherapy?].
Topics: Age Factors; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Lymphatic Metastasis; Melphalan; Menopause; Methotrexate; Prognosis | 1980 |
Multimodal treatment in operable breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukemia; Methotrexate; Middle Aged | 1981 |
Prospective study with HEXA-CAF combination in ovarian carcinoma.
Topics: Altretamine; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms; Ovary | 1981 |
Chemotherapy of pancreatic adenocarcinoma: initial report on two transplantable models in the Syrian hamster.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cricetinae; Cyclophosphamide; Disease Models, Animal; Fluorouracil; Guinea Pigs; Male; Mesocricetus; Methotrexate; Mitomycin; Mitomycins; Neoplasms, Experimental; Pancreatic Neoplasms; Vincristine | 1982 |
[Chemotherapy of advanced breast cancer--actual results ].
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Tegafur; Vincristine | 1982 |
[The use of lithium carbonate in mastectomized patients undergoing cancer therapy].
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Leukopenia; Lithium; Lithium Carbonate; Mastectomy; Methotrexate; Middle Aged; Postoperative Care; Postoperative Complications | 1982 |
[Possibilities and value of intracavitary and systemic chemotherapy of bladder cancer].
Topics: Antineoplastic Agents; Carcinoma in Situ; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Mitomycin; Mitomycins; Teniposide; Thiotepa; Urinary Bladder; Urinary Bladder Neoplasms | 1982 |
Pathologic findings from the National Surgical Adjuvant Breast Project. VIII. Relationship of chemotherapeutic responsiveness to tumor differentiation.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Methotrexate; Middle Aged; Prognosis | 1983 |
Response to secondary therapy in patients with adenocarcinoma of the breast previously treated with adjuvant chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Receptors, Estrogen; Tamoxifen; Time Factors; Vincristine | 1983 |
Use of high-dose oral methotrexate sequenced at 24 hours with 5-FU: a clinical toxicity study.
Topics: Breast Neoplasms; Colonic Neoplasms; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Neoplasms | 1983 |
[Radiation and combination treatment of breast cancer metastases to the lungs].
Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Staging; Radiotherapy Dosage; Time Factors | 1983 |
Microsomal metabolism of antipyrine in rats treated with antineoplastic drugs.
Topics: Animals; Antineoplastic Agents; Antipyrine; Body Weight; Cyclophosphamide; Fluorouracil; Kinetics; Male; Methotrexate; Microsomes, Liver; Organ Size; Rats; Rats, Inbred Strains | 1983 |
Selenium levels in blood and plasma, and glutathione peroxidase activity in blood of breast cancer patients during adjuvant treatment with cyclophosphamide, methotrexate and 5-fluorouracil.
Topics: Adult; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Glutathione Peroxidase; Humans; Methotrexate; Middle Aged; Peroxidases; Selenium | 1983 |
Reduction of estrogen receptor concentration in MCF-7 human breast carcinoma cells following exposure to chemotherapeutic drugs.
Topics: Breast Neoplasms; Cell Line; Dose-Response Relationship, Drug; Estradiol; Female; Fluorouracil; Humans; Methotrexate; Receptors, Estrogen; Time Factors; Vincristine | 1983 |
Transforming activities of methotrexate, hydroxyurea and 5-fluorouracil in different cell systems.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Dose-Response Relationship, Drug; Ectromelia virus; Fluorouracil; Hydroxyurea; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA | 1983 |
Sequential methotrexate and 5-fluorouracil: mechanisms of synergy.
Topics: Animals; Biotransformation; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Fluorodeoxyuridylate; Fluorouracil; Folic Acid; Humans; Methotrexate; Mice; Neoplasm Transplantation; Sarcoma, Experimental; Thymidylate Synthase; Time Factors | 1983 |
Prednimustine in combination with methotrexate and 5-fluorouracil in advanced breast cancer: a phase I-II study.
Topics: Aged; Breast Neoplasms; Chlorambucil; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Prednimustine | 1983 |
Sequence-dependent synergism between dichloromethotrexate and 5-fluorouracil in a human colon carcinoma cell line.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line; Cell Survival; Colonic Neoplasms; Drug Synergism; Fluorouracil; Humans; Kinetics; Methotrexate; Time Factors | 1983 |
Noncarcinogenic chemotherapy with a combination of vincristine, methotrexate and 5-fluorouracil (VMF) in rats.
Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Fluorouracil; Male; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Time Factors; Vincristine | 1983 |
[Malignant mesothelioma of the peritoneum. Case report].
Topics: Adult; Antineoplastic Agents; Cobalt Radioisotopes; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Mesothelioma; Methotrexate; Peritoneal Neoplasms; Radioisotope Teletherapy; Vincristine | 1983 |
Combined effect of levan and cytotoxic agents on the growth of experimental tumours in mice.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fluorouracil; Fructans; Lung Neoplasms; Lymphoma; Male; Methotrexate; Mice; Mice, Inbred AKR; Mice, Inbred C57BL; Neoplasms, Experimental; Polysaccharides; Vincristine | 1983 |
[Advanced epithelial cancers of the ovary: results of 4 chemotherapy protocols (110 cases)].
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma; Cisplatin; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Laparotomy; Melphalan; Methotrexate; Middle Aged; Neoplasm Staging; Ovarian Neoplasms | 1982 |
Multiple simultaneous and sequential estrogen receptor values in patients with breast cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Prednisone; Receptors, Estrogen; Retrospective Studies; Vincristine | 1982 |
Adriamycin and VP16-213 combination treatment for breast cancer previously treated by the CMF regimen.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Resistance; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Podophyllotoxin | 1982 |
[Our experience with cyclophosphamide, methotrexate and 5-fluorouracil in the postoperative treatment of breast carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Postoperative Care | 1982 |
Effect of time and therapy on the hormone receptor status of breast carcinomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Menopause; Methotrexate; Receptors, Estrogen; Receptors, Progesterone; Time Factors | 1982 |
Adjuvant chemotherapy (CMF) for breast carcinoma: hematological side effects.
Topics: Antineoplastic Combined Chemotherapy Protocols; Body Weight; Breast Neoplasms; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukopenia; Mastectomy; Methotrexate; Nausea; Neoplasm Staging; Platelet Count; Time Factors; Vomiting | 1982 |
Adjuvant CMF effect on site of first recurrence, and appropriate follow-up intervals, in operable breast cancer with positive axillary nodes.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Neoplasm Recurrence, Local; Random Allocation; Soft Tissue Neoplasms; Thoracic Neoplasms; Time Factors | 1981 |
VP-16 and adriamycin in patients with advanced breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Podophyllotoxin; Prednisone; Thrombocytopenia; Vincristine; Vomiting | 1982 |
[Treatment of advanced breast cancer with 2 successive chemotherapeutic schedules].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Prednisone | 1982 |
Life with cytostatic drugs.
Topics: Activities of Daily Living; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Fatigue; Feeding and Eating Disorders; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Patient Acceptance of Health Care; Vincristine | 1980 |
5-Fluorouracil and methotrexate combination chemotherapy: the effect of drug scheduling.
Topics: Animals; Body Weight; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Leukemia L1210; Lung Neoplasms; Methotrexate; Mice; Neoplasms, Experimental; Osteosarcoma; Sarcoma, Experimental | 1981 |
Hypothetical mechanism of therapeutic synergism induced by the combination of 6-thioguanine and 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride.
Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Fluorouracil; Leukemia L1210; Methotrexate; Mice; Mice, Inbred Strains; Nimustine; Nitrosourea Compounds; Thioguanine | 1982 |
Combination chemotherapy with 5-FU 1-(aminomethyl)-3-(2-chloroethyl)-3-nitrosourea (ACNU), and mitomycin (FUM) for carcinoma of the pancreas.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mitomycins; Neoplasm Metastasis; Nimustine; Nitrosourea Compounds; Pancreatic Neoplasms | 1982 |
Mechanisms of levamisole-induced granulocytopenia in breast cancer patients.
Topics: Acute Disease; Adult; Aged; Agranulocytosis; B-Lymphocytes; Breast Neoplasms; Colony-Forming Units Assay; Concanavalin A; Cyclophosphamide; Cytotoxicity, Immunologic; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Hemagglutination Tests; Humans; Levamisole; Methotrexate; Middle Aged; Phytohemagglutinins; T-Lymphocytes | 1980 |
[Treatment of malignant tumors of the oral cavity].
Topics: Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Methotrexate; Mouth Neoplasms | 1980 |
Effect of concurrent calcium leucovorin infusion on 5-fluorouracil cytotoxicity against murine L1210 leukemia.
Topics: Animals; Antineoplastic Agents; Drug Synergism; Fluorouracil; Leucovorin; Leukemia L1210; Male; Methotrexate; Mice; Mice, Inbred DBA; Time Factors | 1981 |
Clinical use of methotrexate--with emphasis on use of high doses.
Topics: Animals; Asparaginase; Brain Diseases; Child, Preschool; Cisplatin; Cytarabine; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Fluorouracil; Humans; Infant; Injections, Spinal; Leucovorin; Leukemia L1210; Leukemia, Lymphoid; Methotrexate; Mice | 1981 |
Prolonged disease-free survival in advanced breast cancer treated with "super-CMF" adriamycin: an alternating regimen employing high-dose methotrexate with citrovorum factor rescue.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leucovorin; Leukocyte Count; Methotrexate; Middle Aged; Pilot Projects; Prognosis | 1981 |
Sequential methotrexate and 5-FU in the treatment of colorectal cancer.
Topics: Colonic Neoplasms; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Follow-Up Studies; Humans; Injections, Intravenous; Leucovorin; Methotrexate; Rectal Neoplasms | 1982 |
Clinical and pharmacological studies of methotrexate-minimal leucovorin rescue plus fluorouracil.
Topics: Adult; Aged; Bone Marrow; Drug Therapy, Combination; Female; Fluorouracil; Half-Life; Humans; Kinetics; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasms | 1982 |
Effect of feeder cell-released substances on the survival of clonogenic 9L cells after treatment with antimetabolites.
Topics: Animals; Antimetabolites, Antineoplastic; Brain Neoplasms; Cell Line; Cell Survival; Clone Cells; Colony-Forming Units Assay; Cytological Techniques; Drug Evaluation, Preclinical; Fluorouracil; Methotrexate; Mice; Neoplasms, Experimental; Rats | 1980 |
Brain metastases in breast cancer patients receiving adjuvant chemotherapy.
Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Neoplasm Staging; Probability; Retrospective Studies | 1982 |
[Sequential methotrexate and fluorouracil in metastasizing colorectal carcinomas. Results of a phase II pilot study (author's transl)].
Topics: Adult; Aged; Colonic Neoplasms; Female; Fluorouracil; Humans; Life Expectancy; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms; Time Factors | 1982 |
Initial chemoimmunotherapy in inflammatory carcinoma of the breast.
Topics: Aged; Antineoplastic Agents; BCG Vaccine; Breast Neoplasms; Carcinoma; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Thermography; Time Factors; Vincristine | 1982 |
High-frequency low-dose multiple-drug chemotherapy in advanced metastatic breast cancer.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Vinblastine | 1982 |
Phase II study of sequential methotrexate-5-FU therapy in advanced measurable colorectal cancer.
Topics: Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Follow-Up Studies; Humans; Injections, Intravenous; Methotrexate; Neoplasm Metastasis; Rectal Neoplasms | 1982 |
Modulation of 5-FU metabolism in human MCF-7 breast carcinoma cells.
Topics: Breast Neoplasms; Cells, Cultured; Female; Fluorouracil; Humans; Methotrexate; Methylthioinosine; RNA, Neoplasm | 1982 |
The medical management of breast cancer.
Topics: Adjuvants, Pharmaceutic; Adult; Aminoglutethimide; Antineoplastic Agents; Breast Neoplasms; Castration; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hypophysectomy; Melphalan; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Receptors, Estrogen; Tamoxifen | 1982 |
Sensitization to low dose 5-fluorouracil. Subsequent enhancement of its systemic antitumor effect in the rat.
Topics: Animals; Female; Fluorouracil; Male; Mammary Neoplasms, Experimental; Methotrexate; Neoplasm Metastasis; Neoplasms, Experimental; Rats | 1982 |
Estrogen receptor status in inflammatory breast carcinoma.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Receptors, Estrogen; White People | 1982 |
[Effect of antiblastic polychemotherapy (CMF) on the number of circulating monocytes in patients with breast cancer].
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Monocytes; Tamoxifen | 1982 |
Formation of UV-induced apoptosis relates to the cell cycle.
Topics: Animals; Cell Count; Cell Cycle; Cell Division; Cell Survival; Colchicine; Fluorouracil; Guinea Pigs; Hydroxyurea; Methotrexate; Skin; Sunburn; Ultraviolet Rays | 1982 |
Response to oophorectomy after tamoxifen failure in a premenopausal patient.
Topics: Adult; Breast Neoplasms; Castration; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Menopause; Methotrexate; Tamoxifen | 1982 |
Monitoring the effect of anti-cancer drugs on L1210 cells by a mitochondrial probe, rhodamine-123.
Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; DNA; Flow Cytometry; Fluorouracil; Leukemia L1210; Methotrexate; Mice; Mitochondria; Rhodamines; Xanthenes | 1982 |
Effect of methotrexate on incorporation and excision of 5-fluorouracil residues in human breast carcinoma DNA.
Topics: Breast Neoplasms; Cell Line; DNA, Neoplasm; Female; Fluorouracil; Humans; Kinetics; Methotrexate; Tritium | 1982 |
Prednimustine in combination with methotrexate and 5-FU (PMF): a pilot study.
Topics: Aged; Alopecia; Breast Neoplasms; Chlorambucil; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Nausea; Pilot Projects; Prednimustine; Tamoxifen; Vomiting | 1982 |
Therapy of liver tumors metastatic from colorectal cancer with whole-liver radiation combined with 5-FU, adriamycin, and methotrexate.
Topics: Aged; Colonic Neoplasms; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Rectal Neoplasms | 1982 |
[Chemotherapy schedule for the management of metastasizing gastric cancer. Methotrexate, adriamycin and 5-fluorouracil].
Topics: Adult; Aged; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Stomach Neoplasms | 1982 |
[Advanced carcinoma of the breast. Results of a polychemotherapeutic protocol].
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Vincristine | 1982 |
The selectivity of action of methotrexate in combination with 5-fluorouracil in xenografts of human colon adenocarcinomas.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Drug Interactions; Female; Fluorouracil; Humans; Methotrexate; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Neoplasms, Experimental; Thymectomy; Time Factors | 1982 |
[Medroxyprogesterone acetate (MAP) in high doses in the treatment of breast cancer in advanced stages].
Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Medroxyprogesterone; Methotrexate; Middle Aged | 1982 |
[Combined therapy of advanced gastric cancer].
Topics: Adenocarcinoma; Female; Fluorouracil; Gastrectomy; Humans; Methotrexate; Middle Aged; Stomach Neoplasms | 1982 |
Chemotherapy of hormone-resistant stage D prostatic cancer.
Topics: Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Estramustine; Fluorouracil; Humans; Hydroxyurea; Lomustine; Male; Melphalan; Methotrexate; Prednimustine; Prostatic Neoplasms | 1980 |
Platinum-based combination chemotherapy in non-small cell lung carcinoma.
Topics: Adult; Aged; Antineoplastic Agents; Cisplatin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Vincristine | 1981 |
Basis of observed resistance of L1210 leukemia in mice: methotrexate, 6-thioguanine, 6-methylmercaptopurine riboside, 6-mercaptopurine, 5-fluorouracil, and 1-beta-D-arabinofuranosylcytosine administered in different combinations.
Topics: Animals; Antineoplastic Agents; Biotransformation; Cell Line; Cytarabine; Drug Evaluation, Preclinical; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Fluorouracil; Leukemia L1210; Male; Mercaptopurine; Methotrexate; Methylthioinosine; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Thioguanine | 1981 |
Failure of 5-fluorouracil and methotrexate to destroy the reproductive integrity of a human breast cancer cell line (MCF-7) growing in vitro.
Topics: Breast Neoplasms; Cell Division; Cell Line; Cell Survival; Clone Cells; Deoxyuridine; DNA, Neoplasm; Dose-Response Relationship, Drug; Fluorouracil; Humans; Male; Methotrexate; Thymidine | 1981 |
Treatment of asymptomatic metastatic cancer to the liver from primary colon and rectal cancer by the intraarterial administration of chemotherapy and radioactive isotopes.
Topics: Antineoplastic Agents; Catheters, Indwelling; Cisplatin; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intra-Arterial; Liver Neoplasms; Methotrexate; Prognosis; Rectal Neoplasms; Yttrium Radioisotopes | 1982 |
[Ancillary chemotherapy with trofosfamid, methotrexate and fluoro-uracil in cancer of the breast (author's transl)].
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local | 1981 |
A five-drug combination in the treatment of metastatic breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Carmustine; Dacarbazine; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prednisone | 1981 |
[Effects of immunosuppressive drugs on the fetal-placental unit].
Topics: Animals; Body Weight; Female; Fetal Death; Fetal Resorption; Fluorouracil; Immunosuppressive Agents; Methotrexate; Organ Size; Placenta; Pregnancy; Rats | 1980 |
[Experimental chemotherapy. II: Study of the cytomorphologic effects of radiation and antitumor chemotherapy on neoplastic tissue].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Chick Embryo; Culture Techniques; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Uterine Cervical Neoplasms; Uterine Neoplasms | 1980 |
[Therapeutic effectiveness of carminomycin (CRM) in combination with dibromodulcitol (DBD) compared with the combination vincristine, cyclophosphamide, methotrexate, 5-fluorouracil (VCMF) on some tumor systems (author's transl)].
Topics: Animals; Antineoplastic Agents; Carubicin; Cyclophosphamide; Daunorubicin; Drug Therapy, Combination; Female; Fluorouracil; Methotrexate; Mice; Mice, Inbred Strains; Mitolactol; Neoplasms, Experimental; Vincristine | 1980 |
Results of adjuvant therapy for breast cancer in Phoenix.
Topics: Adult; Aged; Arizona; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged | 1980 |
A study over a 5-year period of adjuvant chemotherapy after mastectomy for breast cancer.
Topics: Breast Neoplasms; Chlorambucil; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Postoperative Care; Time Factors | 1981 |
[Neurotoxic side effects of cytostatic therapy (author's transl)].
Topics: Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Dacarbazine; Dactinomycin; Doxorubicin; Fluorouracil; Humans; Meningitis; Methotrexate; Nervous System Diseases; Nitrosourea Compounds; Procarbazine; Vincristine | 1981 |
Liver assessment in women receiving adjuvant CMF chemotherapy.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver; Liver Function Tests; Methotrexate | 1981 |
Effects of endotoxin on the pharmacology of antineoplastic agents.
Topics: Animals; Antineoplastic Agents; Cytarabine; Dogs; Endotoxins; Female; Fluorouracil; Male; Methotrexate; Microsomes, Liver; Tissue Distribution; Vinblastine | 1981 |
[Combination chemotherapy in metastatic breast cancer].
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis | 1981 |
Chemotherapy for advanced breast cancer.
Topics: Adult; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisolone | 1981 |
[Treatment of advanced breast cancer with cyclophosphamide, methotrexate, 5-fluorouracil and prednisone (CMFP)].
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone | 1981 |
[Results of, and indications for adjuvant chemotherapy in breast cancer].
Topics: Adult; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Risk; Vincristine | 1981 |
[Use of "split" courses of combination chemotherapy in breast cancer].
Topics: Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasm Metastasis; Prednisolone; Time Factors; Vincristine | 1981 |
[Encouraging results with cytostatic therapy in metastasizing breast cancer (author's transl)].
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Prognosis; Vincristine | 1981 |
Cytokinetic and cytotoxic effects of antimetabolites on 9L rat brain tumor cells in vitro.
Topics: Animals; Brain Neoplasms; Cell Cycle; Cell Division; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Fluorouracil; Kinetics; Methotrexate; Rats; Time Factors | 1981 |
Investigations into sister chromatid exchange in patients under cytostatic therapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Child; Child, Preschool; Crossing Over, Genetic; Cyclophosphamide; DNA Repair; Drug Therapy, Combination; Female; Fluorouracil; Humans; Infant; Lung Neoplasms; Male; Methotrexate; Middle Aged; Psoriasis; Sister Chromatid Exchange | 1981 |
Correlation of estrogen receptors and response to chemotherapy of cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) in advanced breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prognosis; Receptors, Estrogen; Time Factors | 1981 |
Combination chemoimmunotherapy with FAC-BCG for metastatic breast cancer: the impact of CMF maintenance chemotherapy.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; BCG Vaccine; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Injections, Intravenous; Methotrexate; Middle Aged; Neoplasm Metastasis | 1981 |
[Free amino acid changes in rat brain after intracysternal injection of antimetabolites -- comparison to those in amyotrophic lateral sclerosis (author's transl)].
Topics: Amino Acids; Amyotrophic Lateral Sclerosis; Animals; Brain; Brain Chemistry; Dactinomycin; Fluorouracil; Injections; Male; Methotrexate; Methylmercury Compounds; Rats | 1981 |
Carcinogenic activity in rats of combined treatment with cyclophosphamide, methotrexate and 5-fluorouracil.
Topics: Adrenal Gland Neoplasms; Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukemia, Experimental; Male; Mammary Neoplasms, Experimental; Methotrexate; Neoplasms, Experimental; Nervous System Neoplasms; Rats; Urinary Bladder Neoplasms | 1981 |
Variations in responsiveness and survival of clinical subsets of patients with metastatic breast cancer to two chemotherapy combinations.
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prednisone; Prognosis; Random Allocation; Vincristine | 1980 |
[Chemotherapy of breast cancer].
Topics: Adult; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Neoplasm Metastasis; Prednisolone; Vincristine | 1981 |
Defective function of granulocytes in patients with cancer.
Topics: Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Granulocytes; Humans; Male; Methotrexate; Middle Aged; Neoplasms; Pancreatic Neoplasms; Stomach Neoplasms; Uterine Neoplasms | 1981 |
[Results of "5-drug" treatment of advanced breast cancer].
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Prednisone; Vincristine | 1981 |
Radiographic evaluation of therapeutic response in bony metastases of breast cancer.
Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Radiography | 1981 |
[Variations of serum BuChe activity during C M F therapy].
Topics: Breast Neoplasms; Butyrylcholinesterase; Cholinesterases; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Mouth Neoplasms | 1981 |
Advantages and limitations of pharmacokinetic studies in the rationalization of anticancer therapy: methotrexate and 5-FU.
Topics: Drug Administration Schedule; Fluorouracil; Humans; Kinetics; Methotrexate; Models, Biological | 1981 |
Adjuvant therapy for stage II, estrogen receptor negative breast cancer.
Topics: Actuarial Analysis; Antineoplastic Agents; Axilla; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Receptors, Estrogen; Recurrence | 1981 |
[Cyclophosphamide, methotrexate and 5-fluorouracil (CMF), versus 5-fluorouracil, in carcinoma of the large intestine in an advanced stage].
Topics: Aged; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Intestinal Neoplasms; Intestine, Large; Male; Methotrexate; Middle Aged | 1980 |
Pharmacokinetic approach to in vitro testing of ovarian cancer cell sensitivity.
Topics: Antineoplastic Agents; Cell Survival; Cytarabine; Dactinomycin; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance; Female; Fluorouracil; Half-Life; Humans; In Vitro Techniques; Melphalan; Methotrexate; Ovarian Neoplasms | 1980 |
Response of a choroidal metastasis to multiple-drug chemotherapy.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Choroid Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Prednisone; Vincristine | 1980 |
The predictive value of serial bone scans in assessing response to chemotherapy in advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Bone and Bones; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Radionuclide Imaging; Retrospective Studies; Vincristine | 1980 |
Combined chemotherapy and radiotherapy for locally advanced breast cancer.
Topics: Adult; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Vincristine | 1980 |
Moderately high-dosage methotrexate medication in metastatic breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Vincristine | 1980 |
Adverse effect of radiotherapy on adjuvant chemotherapy for carcinoma of the breast.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Vincristine | 1980 |
[Adjuvant chemotherapy in breast neoplasms. Clinical and immunologic results].
Topics: Adult; Aged; Breast Neoplasms; Concanavalin A; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Lymphocyte Activation; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis | 1980 |
[Adjuvant chemotherapy of breast neoplasms. Review of the up-to-date results of various studies including the Heidelberg study].
Topics: Adult; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Evaluation Studies as Topic; Female; Fluorouracil; Germany, West; Humans; Menopause; Methotrexate; Middle Aged; Prognosis | 1980 |
Interim report: National Registry of possible Drug-induced Ocular Side Effects.
Topics: Contact Lenses; Drug-Related Side Effects and Adverse Reactions; Eye Diseases; Fluorouracil; Humans; Ibuprofen; Methotrexate; Neomycin; Practolol; Registries; Sterilization; Tamoxifen; Timolol; United States; United States Food and Drug Administration | 1980 |
[Preoperative polychemotherapy in the overall treatment of locally spread breast cancer (immediate results)].
Topics: Adult; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Preoperative Care; Vincristine | 1980 |
Evaluation of nonhormonal cytotoxic chemotherapy in the Nb rat prostate adenocarcinoma: autonomous tumor (18-Pr and 13-Pr).
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Evaluation, Preclinical; Fluorouracil; Male; Methotrexate; Neoplasm Transplantation; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Rats; Time Factors | 1980 |
[Drug pathomorphosis of breast cancer (proceedings)].
Topics: Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Prednisolone; Vincristine | 1980 |
Combination chemotherapy in advanced breast cancer. A report of the Working Party of the Multicentre Cancer Chemotherapy Group.
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Vincristine | 1980 |
Evaluation of chemotherapeutic responsiveness in Nb rat prostate cancer model. 5-fluorouracil, methotrexate, cyclophosphamide, and adriamycin.
Topics: Animals; Cyclophosphamide; Doxorubicin; Fluorouracil; Male; Methotrexate; Neoplasms, Experimental; Prostatic Neoplasms; Rats | 1980 |
Mitomycin C in metastatic breast cancer resistant to hormone therapy and conventional chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Resistance; Drug Therapy, Combination; Female; Fluorouracil; Hormones; Humans; Medroxyprogesterone; Methotrexate; Middle Aged; Mitomycins; Neoplasm Metastasis; Tamoxifen; Vincristine | 1980 |
Chemotherapy of metastatic carcinoma of the breast.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisolone; Prospective Studies | 1980 |
Modern approaches to the treatment of breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Menstruation; Methotrexate; Mortality; Neoplasm Metastasis; Prednisone; Receptors, Estrogen; Time Factors; Vincristine | 1980 |
The non-hormone chemotherapy of prostatic cancer.
Topics: Bone Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Prostatic Neoplasms | 1980 |
Schedule-dependent cytotoxicity of methotrexate and 5-fluorouracil in human colon and breast tumor cell lines.
Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma; Cell Line; Colonic Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Methotrexate | 1980 |
Dose-response effect of adjuvant chemotherapy in breast cancer.
Topics: Aged; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis | 1981 |
[Malignant melanoma of the vagina].
Topics: Adult; BCG Vaccine; Cyclophosphamide; Drug Therapy, Combination; Eyelid Neoplasms; Female; Fluorouracil; Humans; Lymph Node Excision; Melanoma; Methotrexate; Pelvic Exenteration; Vaginal Neoplasms; Vincristine | 1980 |
The use of peritoneal dialysis for delivery of chemotherapy to intraperitoneal malignancies.
Topics: Antineoplastic Agents; Fluorouracil; Humans; Kinetics; Methotrexate; Peritoneal Dialysis; Peritoneal Neoplasms | 1980 |
Cell kinetic factors, single drugs and combination.
Topics: Animals; Antineoplastic Agents; Cell Division; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Interactions; Fluorouracil; Humans; Kinetics; Lomustine; Methotrexate; Vincristine | 1980 |
Studies of the effects of treatment with 5-flourouracil alone and in combination with either cyclophosphamide, methotrexate, or methyl-CCNU on hepatic drug-metabolizing enzymes in murine L1210 leukemia.
Topics: Animals; Cyclophosphamide; Drug Interactions; Fluorouracil; Leukemia L1210; Liver; Male; Methotrexate; Mice; Mixed Function Oxygenases; Oxidoreductases; Semustine | 1980 |
Chemotherapy against human melanoma in the hamster cheek pouch.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cheek; Cricetinae; Cyclophosphamide; Dacarbazine; Doxorubicin; Fluorouracil; Humans; Male; Melanoma; Methotrexate; Middle Aged; Neoplasm Transplantation; Neoplasms, Experimental; Vincristine | 1980 |
[Polyamines and their significance for control of cancer chemotherapy (author's transl)].
Topics: Breast Neoplasms; Carubicin; Cyclophosphamide; Fluorouracil; Humans; Methotrexate; Mitolactol; Polyamines; Putrescine; Spermidine | 1980 |
In vivo interaction of anti-cancer drugs with misonidazole or metronidazole: methotrexate, 5-fluorouracil and adriamycin.
Topics: Animals; Body Weight; Doxorubicin; Drug Therapy, Combination; Fibrosarcoma; Fluorouracil; Leukocyte Count; Male; Mammary Neoplasms, Experimental; Methotrexate; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental | 1980 |
Modulation of 5-fluorouracil metabolism and cytotoxicity by antimetabolite pretreatment in human colorectal adenocarcinoma HCT-8.
Topics: Adenocarcinoma; Cell Division; Cell Line; Cell Survival; Colonic Neoplasms; Fluorouracil; Humans; Methotrexate; Rectal Neoplasms | 1981 |
An optimal, generalized sampling time of 30 +/- 6 h after double dosing in the mouse peripheral blood micronucleus test.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Colchicine; Cyclophosphamide; Cytarabine; Floxuridine; Fluorouracil; Kinetics; Methotrexate; Mice; Mice, Inbred Strains; Micronucleus Tests; Mitomycin; Mutagens; Reticulocytes; Sulfuric Acid Esters; Time Factors | 1995 |
Negative impact of cancer chemotherapy on protein metabolism in healthy and tumor-bearing rats.
Topics: Animals; Antineoplastic Agents; Cachexia; Cisplatin; Cyclophosphamide; DNA; Eating; Female; Fluorouracil; Intestine, Small; Liver; Liver Neoplasms, Experimental; Methotrexate; Muscle, Skeletal; Nitrogen; Organ Size; Proteins; Rats; Rats, Sprague-Dawley; RNA; Weight Loss | 1995 |
[A case of gastric cancer responding well to MTX/5-FU (methotrexate/5-fluorouracil) and PMUE (CDDP, MMC, UFT, etoposide) therapies upon lymphnode recurrence].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Etoposide; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Stomach Neoplasms; Tegafur; Uracil | 1995 |
[Feasibility of a cyclophosphamide methotrexate and 5-fluorouracil regime intravenously administered with and without granulocyte-colony stimulating factor in surgically treated breast carcinoma].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Injections, Intravenous; Male; Methotrexate; Middle Aged | 1993 |
Chemosensitivity testing of human malignant melanoma. A retrospective analysis of clinical response and in vitro drug sensitivity.
Topics: Antineoplastic Agents; Bleomycin; Carboplatin; Carmustine; Cisplatin; Dacarbazine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Fluorouracil; Forecasting; Humans; In Vitro Techniques; Lymphatic Metastasis; Melanoma; Methotrexate; Nitrosourea Compounds; Organophosphorus Compounds; Pilot Projects; Remission Induction; Retrospective Studies; Skin Neoplasms; Tumor Cells, Cultured; Vindesine | 1994 |
Tumour cell detection in the bone marrow of breast cancer patients at primary therapy: results of a 3-year median follow-up.
Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow; Breast Neoplasms; Carcinoma; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Immunohistochemistry; Keratins; Lymphatic Metastasis; Methotrexate; Middle Aged; Postmenopause; Premenopause; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Recurrence; Survival Analysis; Tamoxifen; Time Factors | 1994 |
Chemotherapy of recurrent/advanced cervical cancer: results of the Yale University PBM-PFU protocol.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Cisplatin; Female; Fluorouracil; Humans; Leucovorin; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Survival Analysis; Treatment Outcome; Uterine Cervical Neoplasms | 1994 |
Clostridium septicum abscess in hepatic metastases: successful medical management.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Carmustine; Ceftazidime; Cisplatin; Clindamycin; Clostridium Infections; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Gases; Granulocyte Colony-Stimulating Factor; Humans; Imipenem; Immunocompromised Host; Liver Abscess; Liver Neoplasms; Methotrexate; Neutropenia; Sepsis | 1994 |
Anaplastic large cell lymphoma (CD30 +/Ki-1+): results of a prospective clinico-pathological study of 69 cases.
Topics: Adolescent; Adult; Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Fluorouracil; Humans; Immunoenzyme Techniques; Ki-1 Antigen; Leucovorin; Lymphoma, Large-Cell, Anaplastic; Male; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Vincristine | 1994 |
Changes in Tc-99m radionuclide bone scan images and peripheralization of marrow hematopoietic activity associated with the administration of granulocyte colony stimulating factor as an adjunct to dose-intensified chemotherapy for breast cancer. A case rep
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Breast Neoplasms; Carcinoma, Ductal, Breast; Cyclophosphamide; Doxorubicin; Fatal Outcome; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cells; Humans; Methotrexate; Radionuclide Imaging; Recurrence; Technetium | 1994 |
Characterization of trimethoprim- and sulphisoxazole-resistant Chlamydia trachomatis.
Topics: Adenosine Triphosphate; Animals; Chlamydia trachomatis; DNA, Bacterial; Drug Resistance, Microbial; Fluorouracil; Guanosine Triphosphate; L Cells; Methotrexate; Mice; Microbial Sensitivity Tests; Mutation; Phenotype; RNA, Bacterial; Sulfisoxazole; Thymidine; Trimethoprim; Uracil; Zidovudine | 1994 |
HIV-1 expression induced by anti-cancer agents in latently HIV-1-infected ACH2 cells.
Topics: Antineoplastic Agents; Azacitidine; Base Sequence; CD4-Positive T-Lymphocytes; Cell Line; Cell Survival; Cytarabine; DNA; Fluorouracil; HIV-1; Methotrexate; Methylation; Molecular Sequence Data; NF-kappa B; Phytohemagglutinins; Tetradecanoylphorbol Acetate; Vinblastine | 1995 |
Influence of various immunosuppressive agents on the occurrence of endogenous bacteraemia in mice.
Topics: Animals; Bacteremia; Cisplatin; Cyclophosphamide; Enterobacteriaceae Infections; Fluorouracil; Immunosuppressive Agents; Male; Methotrexate; Mice; Pseudomonas Infections; Specific Pathogen-Free Organisms; Tacrolimus | 1995 |
Palliative chemotherapy with CMF after the same adjuvant regimen for breast cancer. The Breast Cancer Study Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Palliative Care; Salvage Therapy; Survival Rate | 1995 |
[Persistent granulocytosis and hyperuricemia after a single G-CSF injection (Filgrastim) in treatment of chemotherapy-induced myelosuppression in metastatic breast carcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Filgrastim; Fluorouracil; Granulocyte Colony-Stimulating Factor; Granulocytes; Humans; Injections, Subcutaneous; Leukocyte Count; Methotrexate; Radiotherapy, Adjuvant; Recombinant Proteins; Uric Acid | 1995 |
Cyclophosphamide, methotrexate, 5-fluorouracil, and folinic acid (CMFF) as first line chemotherapy for treatment of advanced breast cancer. A pilot study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Leucovorin; Methotrexate; Middle Aged; Pilot Projects | 1995 |
Ethmoid sinus leiomyosarcoma after cyclophosphamide treatment.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinogens; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Ethmoid Sinus; Female; Fluorouracil; Follow-Up Studies; Humans; Leiomyosarcoma; Mastectomy, Modified Radical; Melphalan; Methotrexate; Neoplasms, Second Primary; Paranasal Sinus Neoplasms | 1995 |
[Complications in the intraperitoneal chemotherapy with the implantable intraperitoneal port and the strategy for the prevention of the complication].
Topics: Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Cisplatin; Fluorouracil; Gastrointestinal Neoplasms; Humans; Infusion Pumps, Implantable; Infusions, Parenteral; Intestinal Perforation; Male; Methotrexate; Middle Aged; Pain | 1995 |
Chemotherapy and radiation therapy for laryngeal cancer.
Topics: Antineoplastic Agents; Bleomycin; Cisplatin; Drug Combinations; Fluorouracil; Humans; Laryngeal Neoplasms; Larynx; Methotrexate; Neoplasm Staging; Radiation Dosage; Treatment Outcome | 1995 |
Response of Saccharomyces cerevisiae strains to antineoplastic agents.
Topics: Antineoplastic Agents; Cisplatin; Doxorubicin; Fluorouracil; Methotrexate; Microbial Sensitivity Tests; Saccharomyces cerevisiae | 1995 |
Oncogene amplification and prognosis in breast cancer: relationship with systemic treatment.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fibroblast Growth Factor 3; Fibroblast Growth Factors; Fluorouracil; Gene Amplification; Genetic Markers; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Oncogenes; Progestins; Prognosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Receptor, ErbB-2; Risk Factors; Survival Rate; Tamoxifen; Treatment Outcome | 1995 |
[Advanced gastric carcinoma with extensive lymph node metastases successfully treated by sequential methotrexate/5-fluorouracil therapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Leucovorin; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Remission Induction; Stomach Neoplasms | 1995 |
Adjuvant chemotherapy in breast cancer.
Topics: Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Premenopause; Time Factors; Treatment Outcome | 1995 |
[Leukemia in patients with breast carcinoma after adjuvant chemotherapy and/or postoperative radiotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Leukemia; Leukemia, Radiation-Induced; Manitoba; Melphalan; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasms, Second Primary; Postoperative Care; Radiotherapy, Adjuvant; Time Factors | 1995 |
Breast cancer: are imaging studies cost effective following breast cancer and adjuvant therapy?
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Cyclophosphamide; Diagnostic Imaging; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Node Excision; Mastectomy, Segmental; Methotrexate; Neoplasm Recurrence, Local; Treatment Outcome | 1995 |
Doxorubicin followed by cyclophosphamide, methotrexate, and fluorouracil for breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate | 1995 |
[Possibilities and limits of surgical therapy of pseudomyxoma peritonei].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Fluorouracil; Humans; Infusions, Parenteral; Interferons; Leucovorin; Male; Methotrexate; Middle Aged; Peritoneum; Pseudomyxoma Peritonei; Retrospective Studies | 1993 |
Penile cancer chemotherapy: twelve years' experience at Institut Gustave-Roussy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Epirubicin; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Penile Neoplasms; Survival Rate; Treatment Outcome; Vinblastine | 1993 |
Locally advanced breast cancer: is surgery warranted following chemotherapy?
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Node Excision; Mastectomy, Simple; Menopause; Methotrexate; Middle Aged; Neoplasm Staging; Neoplasm, Residual; Postoperative Care; Premenopause; Radiotherapy Dosage; Retrospective Studies; Survival Rate | 1995 |
Epirubicin chemotherapy and advanced breast cancer after adjuvant CMF chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Outcome Assessment, Health Care; Retrospective Studies; Survival Rate | 1995 |
Erythrocyte antioxidant enzyme activity in CMF treated breast cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Catalase; Cyclophosphamide; Erythrocyte Membrane; Erythrocytes; Fluorouracil; Glucosephosphate Dehydrogenase; Glutathione Peroxidase; Glutathione Reductase; Humans; Lipid Peroxidation; Malondialdehyde; Methotrexate; Reference Values; Superoxide Dismutase | 1994 |
Involvement of potassium ions in the action of various antineoplastic drugs on the growth of Saccharomyces cerevisiae.
Topics: Amsacrine; Antineoplastic Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Drug Resistance, Microbial; Fluorouracil; Melphalan; Methotrexate; Potassium Chloride; Saccharomyces cerevisiae | 1993 |
Antibiotic C3368-A, a fungus-derived nucleoside transport inhibitor, potentiates the activity of antitumor drugs.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzofurans; Biological Transport; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Division; Colonic Neoplasms; Doxorubicin; Drug Synergism; Female; Fluorouracil; Humans; KB Cells; Liver Neoplasms; Methotrexate; Mice; Mice, Inbred BALB C; Mitomycin; Spiro Compounds; Thymidine; Tumor Cells, Cultured; Tumor Stem Cell Assay; Uridine | 1995 |
Addition of leucovorin in modulation of 5-fluorouracil with methotrexate: potentiating or reversing effect?
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cell Division; Female; Fluorodeoxyuridylate; Fluorouracil; Humans; Leucovorin; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Tumor Cells, Cultured | 1995 |
Reduced mitogenic stimulation of peripheral blood mononuclear cells as a prognostic parameter for the course of breast cancer: a prospective longitudinal study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Humans; Longitudinal Studies; Lymphatic Metastasis; Lymphocyte Activation; Lymphocytes; Menopause; Methotrexate; Middle Aged; Neoplasm Staging; Phytohemagglutinins; Predictive Value of Tests; Prognosis; Prospective Studies; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1995 |
[Tumor markers CEA, CA 15-3, MCA, TPA, ferritin and PTH in the diagnosis and monitoring of primary breast cancer].
Topics: Adolescent; Adult; Aged; Antigens, Tumor-Associated, Carbohydrate; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Carcinoembryonic Antigen; Cisplatin; Female; Ferritins; Fluorouracil; Humans; Mastectomy, Radical; Methotrexate; Middle Aged; Mucin-1; Parathyroid Hormone; Postoperative Period; Prognosis; Radiotherapy Dosage | 1995 |
[The use of endolymphatic chemotherapy in patients with metastatic stomach cancer].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Signet Ring Cell; Cisplatin; Female; Fluorouracil; Humans; Injections, Intralymphatic; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Stomach Neoplasms | 1994 |
[Case report of long-term survivor of advanced gastric cancer associated with peritoneal dissemination successfully treated with cancer chemotherapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Gastrectomy; Humans; Leucovorin; Methotrexate; Peritoneal Neoplasms; Prognosis; Stomach Neoplasms; Tegafur; Uracil | 1995 |
Alterations in erythrocyte membrane structure of breast cancer patients treated with CMF--a lipid profile.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cholesterol; Cyclophosphamide; Erythrocyte Membrane; Fluorouracil; Humans; Lipid Peroxidation; Membrane Fluidity; Methotrexate; Phospholipids | 1994 |
[A case report: postoperative recurrence of peritoneal dissemination of gastric cancer responding to sequential methotrexate and 5-FU (5-fluorouracil)].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Gastrectomy; Humans; Methotrexate; Middle Aged; Peritoneal Neoplasms; Stomach Neoplasms | 1995 |
Chemotherapy induced refractory anaemia with ring sideroblasts in carcinoma breast.
Topics: Aged; Anemia, Refractory; Anemia, Sideroblastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Peptichemio; Radiotherapy, Adjuvant | 1994 |
Pathologic response to induction chemotherapy in locally advanced carcinoma of the breast: a determinant of outcome.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Mastectomy, Modified Radical; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Preoperative Care; Prognosis; Remission Induction; Retrospective Studies; Survival Rate; Treatment Outcome | 1995 |
Effect of 5-fluorouracil on methotrexate transport and cytotoxicity in HT29 colon adenocarcinoma cells.
Topics: Adenocarcinoma; Biological Transport; Colonic Neoplasms; Drug Administration Schedule; Drug Synergism; Fluorouracil; Glutathione; Humans; Intracellular Fluid; Methotrexate; Tumor Cells, Cultured | 1995 |
Synchronization of cells in the S phase of the cell cycle by 3'-azido-3'-deoxythymidine: implications for cell cytotoxicity.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Division; Cell Survival; Colonic Neoplasms; Computer Simulation; DNA, Neoplasm; Drug Synergism; Flow Cytometry; Fluorouracil; Humans; Leukemia; Melanoma; Methotrexate; Pancreatic Neoplasms; S Phase; Tumor Cells, Cultured; Zidovudine | 1995 |
Experimental combination chemotherapy of pirarubicin with various antitumor drugs against P388 murine leukemia.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Leukemia P388; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred BALB C; Mitomycin; Peplomycin; Vindesine | 1994 |
Chemotherapy-induced differential changes in lymphocyte subsets and natural-killer-cell function in patients with advanced breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Breast Neoplasms; CD4-Positive T-Lymphocytes; Cisplatin; Fluorouracil; Humans; Immunophenotyping; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Leukocyte Count; Lymphocyte Subsets; Methotrexate | 1993 |
Fine-needle aspiration cytology in locally advanced breast adenocarcinoma: a case with complete response to preoperative chemotherapy in association with granulomatous inflammatory reaction.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Granuloma; Humans; Inflammation; Methotrexate; Preoperative Care; Treatment Outcome | 1994 |
Targeted and non-targeted actions of anti-cancer drugs.
Topics: Animals; Antimetabolites, Antineoplastic; Bone Marrow; Cycloheximide; Deoxycytidine Kinase; Fluorouracil; Hypoxanthine Phosphoribosyltransferase; Isoxazoles; Methotrexate; Neoplasms, Experimental; Pyrimidines; Rats; Rats, Inbred Strains; Ribavirin; Thymidine Kinase; Thymidylate Synthase | 1994 |
[A case report: multiple liver metastasis from gastric cancer responding to intraarterial infusion of sequential low-dose MTX and 5-FU].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Methotrexate; Stomach Neoplasms | 1994 |
[Dual arterial infusion chemotherapy, continuous hyperthermic peritoneal perfusion, and total parietal peritonectomy for peritoneal dissemination in gastric cancer--a case report].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; Fluorouracil; Humans; Hyperthermia, Induced; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Infusions, Parenteral; Male; Methotrexate; Peritoneal Neoplasms; Peritoneum; Stomach Neoplasms | 1994 |
[Adriamycin/cyclophosphamide: current standard in adjuvant therapy for breast carcinoma?].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Heart; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged | 1994 |
[The mechanism of biochemical modulation in methotrexate/5-fluorouracil sequential chemotherapy].
Topics: Animals; Drug Administration Schedule; Drug Synergism; Fluorouracil; Methotrexate; Mice; RNA, Neoplasm; Sarcoma 180; Thymidylate Synthase; Tumor Cells, Cultured | 1994 |
Effects of a modified CMF treatment (cyclophosphamide, methotrexate and 5-fluorouracil) on hematopoietic tissues and Yoshida sarcoma in rats.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Screening Assays, Antitumor; Female; Fluorouracil; Hematopoietic Stem Cells; Methotrexate; Neoplasm Transplantation; Rats; Rats, Wistar; Sarcoma, Yoshida; Spleen | 1994 |
Computer model challenges breast cancer treatment strategy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Calibration; Cell Cycle; Cisplatin; Clinical Trials as Topic; Computer Simulation; Databases, Factual; Fluorouracil; Humans; Methotrexate; Models, Biological; Reproducibility of Results; Retrospective Studies | 1994 |
Histologic grade of locally advanced infiltrating ductal carcinoma after treatment with induction chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Biopsy, Needle; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Preoperative Care | 1994 |
Effect of modulators on 5-fluorouracil metabolite patterns in murine colon carcinoma determined by in vitro 19F nuclear magnetic resonance spectroscopy.
Topics: Animals; Aspartic Acid; Colonic Neoplasms; Female; Fluorine; Fluorouracil; Interferon-alpha; Leucovorin; Magnetic Resonance Spectroscopy; Methotrexate; Mice; Mice, Inbred C57BL; Phosphonoacetic Acid; Rats; Tumor Cells, Cultured | 1994 |
Adjuvant therapy for breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Humans; Methotrexate | 1994 |
[Hydrodynamics of the rabbit eye after general administration of cytostatics].
Topics: Animals; Biological Transport, Active; Ciliary Body; Fluorouracil; Intraocular Pressure; Methotrexate; Potassium; Rabbits; Sodium; Vincristine | 1994 |
[The tumor pathomorphosis and status of the regional lymph nodes after the preoperative polychemotherapy of patients with vulvar cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Injections, Intralymphatic; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Preoperative Care; Prospidium; Vulvar Neoplasms | 1993 |
[Simultaneous radiochemotherapy in locoregional recurrent breast carcinoma after mastectomy. Results in patients with macroscopic residual tumor R2].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Radiotherapy Dosage; Retrospective Studies; Time Factors | 1994 |
[A case of gastric cancer completely responding to sequential methotrexate and 5-fluorouracil therapy].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Remission Induction; Stomach Neoplasms | 1994 |
[Neoadjuvant chemotherapy for elderly advanced gastric cancer: a case report of MTX/5-FU sequential therapy followed by radical gastrectomy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Male; Methotrexate; Stomach Neoplasms | 1994 |
Adjuvant systemic therapy and survival after breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Retrospective Studies; Survival Rate; Tamoxifen; Treatment Outcome | 1994 |
The phase of the menstrual cycle has no influence on the disease-free survival of patients with mammary carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Estradiol; Female; Fluorouracil; Follicle Stimulating Hormone; Follow-Up Studies; Humans; Luteinizing Hormone; Mastectomy, Radical; Mastectomy, Segmental; Menstrual Cycle; Methotrexate; Neoplasm Staging; Progesterone; Receptors, Steroid; Retrospective Studies; Survival Analysis; Time Factors | 1994 |
[Neoadjuvant chemotherapy for far-advanced gastric carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Methotrexate; Mitomycin; Preoperative Care; Stomach Neoplasms; Survival Rate | 1994 |
[Combined treatment of radiotherapy, neo-adjuvant chemotherapy and adjuvant chemotherapy for nasopharyngeal carcinoma].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Radiotherapy, High-Energy | 1994 |
High-dose, brief duration, multiagent chemotherapy for metastatic breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Fluorouracil; Follow-Up Studies; Hemorrhage; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Neutropenia; Remission Induction; Survival Rate; Thrombocytopenia | 1994 |
Variability in the pharmacokinetics of cyclophosphamide, methotrexate and 5-fluorouracil in women receiving adjuvant treatment for breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged | 1994 |
Levels of viral glycoprotein reflect enhanced effectiveness of combined drug treatments.
Topics: Adenocarcinoma; Animals; Antigens, Viral, Tumor; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Screening Assays, Antitumor; Extracellular Space; Fluorouracil; Glycoproteins; Kinetics; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methotrexate; Mice; Mice, Inbred C3H; Tamoxifen; Viral Envelope Proteins | 1994 |
Intensive chemotherapy with autologous bone marrow transfusion as primary treatment in women with breast cancer and more than five involved axillary lymph nodes.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Chemotherapy, Adjuvant; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Prednisone; Prognosis; Vincristine | 1994 |
Colon carcinoid tumors. A population-based study.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Chemotherapy, Adjuvant; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Streptozocin; Survival Rate | 1994 |
Phosphorus-31 metabolism of post-menopausal breast cancer studied in vivo by magnetic resonance spectroscopy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Magnetic Resonance Spectroscopy; Methotrexate; Middle Aged; Phosphates; Phosphocreatine; Phosphorus; Postmenopause; Reference Values; Ribonucleotides | 1994 |
Identification of a previously unknown compound as 2'-deoxycytidine found in the plasma of breast cancer patients under combined chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cisplatin; Deoxycytidine; Electrophoresis; Female; Fluorouracil; Humans; Methotrexate; Spectrophotometry, Ultraviolet | 1994 |
Carboquone combined with methotrexate and 5-fluorouracil for recurrent and advanced ovarian cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Ovarian Neoplasms | 1993 |
Development and validation of a limited sampling strategy for 5-fluorouracil given by bolus intravenous administration.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Injections, Intravenous; Methotrexate; Middle Aged; Models, Biological; Reproducibility of Results | 1993 |
Combination of reduced folates with methotrexate or 5-fluorouracil. Comparison between 5-formyltetrahydrofolate (folinic acid) and 5-methyltetrahydrofolate in vitro activities.
Topics: Antineoplastic Agents; Cell Division; Drug Stability; Drug Synergism; Fluorouracil; Humans; Leucovorin; Methotrexate; Oxidation-Reduction; Stereoisomerism; Tetrahydrofolates; Tumor Cells, Cultured | 1993 |
[A study of first and second line chemotherapies in gestational choriocarcinoma].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Dactinomycin; Drug Administration Schedule; Etoposide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Pregnancy; Prognosis; Uterine Neoplasms; Vincristine | 1993 |
[Successful treatment of recurrent multiple lung metastasis from colon cancer with combination chemotherapy using methotrexate, 5-fluorouracil, and high-dose leucovorin: a case report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Lung Neoplasms; Male; Methotrexate; Neoplasm Recurrence, Local; Remission Induction; Sigmoid Neoplasms | 1993 |
Dose intensity. The neglected variable in clinical trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Methotrexate; Multicenter Studies as Topic; Research Design; Treatment Outcome | 1993 |
[A case of nonresectable gastric cancer treated by sequential methotrexate and 5-fluorouracil].
Topics: Adenocarcinoma, Scirrhous; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intravenous; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 1994 |
[A case of Borrmann type 4 gastric cancer responding to sequential methotrexate and 5-fluorouracil combined with CDDP].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Stomach Neoplasms | 1994 |
The interval between methotrexate and leucovorin determines the efficacy of 5-fluorouracil modulation in vitro and in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cell Line; Colonic Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Leucovorin; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Time Factors; Transplantation, Heterologous; Tumor Cells, Cultured | 1993 |
A pilot study of cisplatin based combination chemotherapy in gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Epirubicin; Fluorouracil; Humans; Methotrexate; Middle Aged; Pilot Projects; Remission Induction; Stomach Neoplasms | 1993 |
Differential expression of the human mucin genes MUC1 to MUC5 in relation to growth and differentiation of different mucus-secreting HT-29 cell subpopulations.
Topics: Blotting, Northern; Cell Differentiation; Cell Division; Cell Line; Fluorescent Antibody Technique; Fluorouracil; Gene Expression Regulation; Humans; Methotrexate; Mucins; Mucus; Phenotype; RNA, Messenger | 1993 |
Breast cancer in Western Australia in 1989. II. Diagnosis and primary management.
Topics: Antineoplastic Combined Chemotherapy Protocols; Australia; Breast Neoplasms; Cisplatin; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Tamoxifen | 1993 |
Decreased folylpolyglutamate synthetase expression: a novel mechanism of fluorouracil resistance.
Topics: Adenocarcinoma; Base Sequence; Colonic Neoplasms; DNA, Neoplasm; Drug Resistance; Fluorouracil; Humans; Methotrexate; Molecular Sequence Data; Peptide Synthases; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1993 |
PS2 in breast cancer--alternative or complementary tool to steroid receptor status? Evaluation of 446 cases.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cathepsin D; Chemotherapy, Adjuvant; Cyclophosphamide; Estrogens; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Neoplasm Proteins; Neoplasm Staging; Prognosis; Proteins; Radioimmunoassay; Receptors, Estrogen; Receptors, Progesterone; Recurrence; Survival Analysis; Tamoxifen; Time Factors; Trefoil Factor-1; Tumor Suppressor Proteins | 1993 |
Pharmacokinetics and in vitro studies of l-leucovorin. Comparison with the d and d,l-leucovorin.
Topics: Drug Synergism; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Pediococcus; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stereoisomerism; Tumor Cells, Cultured | 1993 |
Predictors of self-care: a test of Orem's model.
Topics: Activities of Daily Living; Adaptation, Psychological; Affect; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Forecasting; Health Promotion; Humans; Male; Methotrexate; Middle Aged; Models, Nursing; Neoplasms; Nursing Evaluation Research; Power, Psychological; Regression Analysis; Self Care; Social Support; Surveys and Questionnaires | 1993 |
[Intraarterial infusion chemotherapy for recurrent or unresectable gastric cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Mitomycin; Peritonitis; Prognosis; Stomach Neoplasms; Survival Rate | 1993 |
[Evaluation of intra-arterial infusion chemotherapy and radical pancreatectomy in patients with locally advanced pancreatic cancer].
Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Doxorubicin; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intra-Arterial; Methotrexate; Neoplasm Invasiveness; Pancreatectomy; Pancreatic Neoplasms; Survival Rate | 1993 |
The release of cytotoxic drugs from acrylic bone cement.
Topics: Animals; Antineoplastic Agents; Bone Cements; Buffers; Cisplatin; Diffusion; Fibrosarcoma; Fluorouracil; Gentamicins; Methotrexate; Methylmethacrylate; Methylmethacrylates; Mice; Rabbits; Sarcoma, Experimental | 1993 |
Hormonal therapy in the treatment of mandibular metastasis of breast carcinoma. Report of a case.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Mandibular Neoplasms; Methotrexate; Tamoxifen | 1993 |
Evaluation of lymphocyte immunity in breast cancer patients.
Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Breast Neoplasms; Cisplatin; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Immunity, Cellular; Immunocompetence; Lymphocyte Activation; Lymphocytes; Methotrexate; Phytohemagglutinins; Pokeweed Mitogens; Reference Values; Stimulation, Chemical; T-Lymphocytes; Tamoxifen | 1993 |
The management of male breast cancer in Nigerians.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Male; Mastectomy, Simple; Methotrexate; Middle Aged; Neoplasm Staging; Nigeria; Treatment Outcome | 1993 |
The use of cyclophosphamide, methotrexate, and 5-fluorouracil in the treatment of Merkel cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Merkel Cell; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Remission Induction; Skin Neoplasms | 1993 |
Impact of irradiation of residual breast on adjuvant chemotherapy dose intensity.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Tamoxifen | 1993 |
Cytogenetic findings in 111 ovarian cancer patients: therapy-related chromosome aberrations and heterochromatic variants.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Chromosome Aberrations; Chromosome Deletion; Chromosome Inversion; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 9; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Heterochromatin; Humans; Karyotyping; Melphalan; Methotrexate; Middle Aged; Mitomycins; Neoplasms, Second Primary; Ovarian Neoplasms; Radiotherapy; Translocation, Genetic; Vincristine | 1993 |
[Alternative combination chemotherapy with mitomycin C, vincristine, methotrexate, 5-fluorouracil, cis-platinum and adriamycin for adenocarcinoma of the lung].
Topics: Adenocarcinoma; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Injections, Intravenous; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Survival Rate; Vincristine | 1993 |
Uridine allows dose escalation of 5-fluorouracil when given with N-phosphonacetyl-L-aspartate, methotrexate, and leucovorin.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Diarrhea; Drug Synergism; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Mucosa; Neoplasms; Phosphonoacetic Acid; Stomatitis; Uridine | 1993 |
Isolation and characterization of a human ileocecal carcinoma cell line (HCT-8) subclone resistant to fluorodeoxyuridine.
Topics: Antimetabolites, Antineoplastic; Cell Division; Colonic Neoplasms; Drug Resistance; Floxuridine; Fluorouracil; Humans; Methotrexate; Quinazolines; Tetrahydrofolates; Thiophenes; Thymidine Kinase; Thymidine Phosphorylase; Thymidylate Synthase; Tumor Cells, Cultured | 1993 |
[A new sequential chemotherapy of methotrexate with 5-fluorouracil against advanced colo-rectal cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged; Rectal Neoplasms; Retrospective Studies; Survival Rate | 1993 |
[A case of advance colon cancer responding to sequential methotrexate and 5-fluorouracil therapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Remission Induction; Tegafur; Uracil | 1993 |
Induction chemotherapy and intensification with autologous bone marrow reinfusion in patients with locally advanced and disseminated breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Prednisone; Prognosis; Remission Induction; Time Factors; Transplantation, Autologous; Vincristine | 1993 |
Trait anxiety and anticipatory immune reactions in women receiving adjuvant chemotherapy for breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Conditioning, Classical; Cytotoxicity, Immunologic; Female; Fluorouracil; Granulocytes; Home Care Services; Hospitalization; Humans; Immunologic Deficiency Syndromes; Leukocyte Count; Lymphocyte Activation; Lymphocyte Subsets; Mastectomy; Methotrexate; Middle Aged; Nausea; Psychoneuroimmunology; Psychophysiologic Disorders; Vomiting, Anticipatory | 1993 |
Efficacy and tolerability of 4-hydroxyandrostenedione (4-OHA) as first-line treatment in postmenopausal patients with breast cancer after adjuvant therapy.
Topics: Aged; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Remission Induction; Tamoxifen; Treatment Outcome | 1993 |
Is chemotherapy associated with development of Barrett's esophagus?
Topics: Adult; Antineoplastic Agents; Barrett Esophagus; Breast Neoplasms; Cisplatin; Drug Therapy, Combination; Female; Fluorouracil; Gastroesophageal Reflux; Humans; Male; Methotrexate; Middle Aged; Testicular Neoplasms | 1993 |
[Quandrantectomy in the conservative treatment of breast carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Italy; Lymph Node Excision; Lymphatic Metastasis; Mastectomy, Segmental; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Postoperative Care; Radiotherapy Dosage; Tamoxifen | 1993 |
GM-CSF in the treatment of a patient with severe methotrexate intoxication.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Drug Overdose; Female; Fluorouracil; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Methotrexate; Postoperative Care; Recombinant Proteins; Time Factors | 1993 |
Mammography in the assessment of response to medical treatment of large primary breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Calcinosis; Cyclophosphamide; Female; Fluorouracil; Humans; Mammography; Methotrexate; Middle Aged; Mitomycin; Mitoxantrone; Tamoxifen | 1993 |
[A case report: multiple liver metastasis of gastric cancer responding to intraarterial infusion of MTX and 5-FU].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Remission Induction; Stomach Neoplasms | 1993 |
5-Fluorouracil metabolism and cytotoxicity after pre-treatment with methotrexate or thymidine in human hypopharynx and colon carcinoma xenografts: a 19F-nuclear magnetic resonance spectroscopy study in vivo.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma; Colonic Neoplasms; Fluorine Radioisotopes; Fluorouracil; Humans; Magnetic Resonance Spectroscopy; Methotrexate; Mice; Mice, Nude; Pharyngeal Neoplasms; Thymidine; Transplantation, Heterologous | 1996 |
Leukotriene E4 selectively increase the delivery of methotrexate to the C6 gliomas in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Autoradiography; Blood Gas Analysis; Brain Neoplasms; Carotid Arteries; Female; Fluorouracil; Glioma; Infusions, Intra-Arterial; Leukotriene E4; Methotrexate; Neoplasm Transplantation; Permeability; Rats; Rats, Wistar; Tumor Cells, Cultured | 1995 |
Neoadjuvant chemotherapy in locally advanced breast cancer.
Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Mastectomy, Modified Radical; Mastectomy, Radical; Mastectomy, Segmental; Methotrexate; Nausea; Neoplasm Recurrence, Local; Vomiting | 1996 |
Vitamin E protects intestinal basolateral membrane from CMF-induced damages in rat.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Fluorouracil; Intestinal Mucosa; Lipid Metabolism; Lipid Peroxides; Male; Membranes; Methotrexate; Rats; Rats, Wistar; Thyrotropin; Vitamin E | 1995 |
[Esthetic results of the conservative treatment in breast carcinoma].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Cisplatin; Cobalt Radioisotopes; Combined Modality Therapy; Esthetics; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Radioisotope Teletherapy; Radiotherapy Dosage; Tamoxifen; Time Factors | 1995 |
Characteristics of cancer cell death after exposure to cytotoxic drugs in vitro.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Death; Dexamethasone; DNA, Neoplasm; Flow Cytometry; Floxuridine; Fluorouracil; Humans; Leukemia-Lymphoma, Adult T-Cell; Methotrexate; Tumor Cells, Cultured; Vincristine | 1996 |
Curing gastric cancer--hone the scalpel with magic?
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Doxorubicin; Fluorouracil; Humans; Methotrexate; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Stomach Neoplasms | 1996 |
Locally advanced breast carcinoma: accuracy of mammography versus clinical examination in the prediction of residual disease after chemotherapy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Estrogens, Conjugated (USP); Female; Fluorouracil; Humans; Mammography; Methotrexate; Middle Aged; Neoplasm, Residual; Predictive Value of Tests; Retrospective Studies; Sensitivity and Specificity; Tamoxifen | 1996 |
Effect of oral chemotherapy on the mitochondrial size of mouse intestinal cells.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Cyclophosphamide; Endoplasmic Reticulum, Rough; Endoplasmic Reticulum, Smooth; Fluorouracil; Gastric Mucosa; Intestine, Small; Jejunum; Methotrexate; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondria, Liver | 1996 |
Combination chemotherapy for breast carcinoma using a combination of cyclophosphamide, methotrexate and 5-fluorouracil (CMF) causes a platelet aggregation defect.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Platelet Aggregation | 1996 |
Primary systemic CD30 (Ki-1)-positive anaplastic large cell lymphoma of the adult: sequential intensive treatment with the F-MACHOP regimen (+/- radiotherapy) and autologous bone marrow transplantation.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Fluorouracil; Humans; Ki-1 Antigen; Lymphoma, Large-Cell, Anaplastic; Male; Methotrexate; Prednisone; Time Factors; Vincristine | 1996 |
Sequential adjuvant therapy: the Memorial Sloan-Kettering Cancer Center experience.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cancer Care Facilities; Cell Division; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; New York City; Paclitaxel; Randomized Controlled Trials as Topic | 1996 |
Future developments for paclitaxel in the treatment of breast cancer.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Female; Fluorouracil; Forecasting; Humans; Methotrexate; Paclitaxel | 1996 |
Pattern of failure in patients with inflammatory breast cancer treated by alternating radiotherapy and chemotherapy.
Topics: Adenocarcinoma; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Feasibility Studies; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Radiotherapy Dosage; Remission Induction; Risk Factors; Survival Rate; Treatment Failure; Vincristine | 1995 |
Possible interactions between antiblastic agents and warfarin inducing prothrombin time abnormalities.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide; Drug Interactions; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitral Valve Stenosis; Prothrombin Time; Time Factors; Warfarin | 1996 |
c-erbB-2 expression and benefit from adjuvant chemotherapy and radiotherapy of breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; DNA, Neoplasm; Female; Fluorouracil; Gene Expression; Genes, erbB-2; Humans; Methotrexate; Neoplasm Recurrence, Local; Premenopause; Receptor, ErbB-2 | 1995 |
The influence of BIBW22BS, a dipyridamole derivative, on the antiproliferative effects of 5-fluorouracil, methotrexate and gemcitabine in vitro and in human tumour xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Deoxycytidine; Dipyridamole; Doxorubicin; Drug Resistance; Female; Floxuridine; Fluorouracil; Gemcitabine; Humans; Methotrexate; Mice; Mice, Nude; Morpholines; Neoplasms; Neoplasms, Experimental; Protein Binding; Transplantation, Heterologous; Triamterene; Tumor Cells, Cultured; Vincristine | 1995 |
Treatment of advanced breast cancer: How much chemotherapy is enough?
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lung Neoplasms; Mastectomy, Segmental; Methotrexate; Middle Aged; Paclitaxel; Tamoxifen | 1996 |
Cisplatin-based neoadjuvant chemotherapy and combined resection for ethmoid sinus adenocarcinoma reaching and/or invading the skull base.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Ethmoid Sinus; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Paranasal Sinus Neoplasms; Retrospective Studies; Skull Neoplasms | 1996 |
[Possibilities of adoptive immunochemotherapy in the treatment of non-small-cell lung cancer].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cyclophosphamide; Dactinomycin; Doxorubicin; Evaluation Studies as Topic; Fluorouracil; Humans; Immunotherapy, Adoptive; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Radiography, Thoracic; Vincristine | 1996 |
Comparison of costs for infusion versus bolus chemotherapy administration: analysis of five standard chemotherapy regimens in three common tumors--Part one. Model projections for cost based on charges.
Topics: Antibiotics, Antineoplastic; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Costs and Cost Analysis; Cyclophosphamide; Disposable Equipment; Doxorubicin; Drug Costs; Etoposide; Fees, Medical; Fees, Pharmaceutical; Female; Fluorouracil; Humans; Infusions, Intravenous; Injections, Intravenous; Leucovorin; Lymphoma, Non-Hodgkin; Methotrexate; Models, Economic; Prednisone; Survival Rate; Vincristine | 1996 |
Comparison of costs for infusion versus bolus chemotherapy administration--Part two. Use of charges versus reimbursement for cost basis.
Topics: Antibiotics, Antineoplastic; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Costs and Cost Analysis; Cyclophosphamide; Doxorubicin; Fees, Pharmaceutical; Female; Fluorouracil; Humans; Infusions, Intravenous; Injections, Intravenous; Leucovorin; Lymphoma, Non-Hodgkin; Medicare; Methotrexate; Prednisone; Private Practice; Reimbursement Mechanisms; United States; Vincristine | 1996 |
Cyclophosphamide, methotrexate, and fluorouracil: still the gold standard?
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Leucovorin; Lymphatic Metastasis; Methotrexate | 1996 |
Hypertensive reactions associated with paclitaxel.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Hypertension; Methotrexate; Middle Aged; Ovarian Neoplasms; Paclitaxel | 1996 |
Intraarterial hepatic chemotherapy with fluorouracil, fluorodeoxyuridine, mitomycin C, cisplatin or methotrexate as single-agent anticancer drugs for a transplanted experimental liver tumor in rats.
Topics: Angiography; Animals; Antineoplastic Agents; Cisplatin; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Injections, Intra-Arterial; Liver Neoplasms, Experimental; Male; Methotrexate; Mitomycin; Neoplasm Transplantation; Prospective Studies; Rats; Rats, Sprague-Dawley | 1996 |
Comparison of chemically induced DNA breakage in cellular and subcellular systems using the comet assay.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antimetabolites, Antineoplastic; Bleomycin; DNA; DNA Damage; Fluorouracil; Hydrogen Peroxide; Leukemia L1210; Methotrexate; Methylnitrosourea; Mice; Mutagenicity Tests; Mutagens; Subcellular Fractions; Tumor Cells, Cultured | 1996 |
Tumor proliferative activity and response to first-line chemotherapy in advanced breast carcinoma.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Cyclophosphamide; Female; Fluorouracil; Humans; Ki-67 Antigen; Methotrexate; Middle Aged; Receptors, Estrogen; Survival Analysis | 1996 |
[Selective arterial catheterization in the management of drug-resistant choriocarcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Drug Resistance, Neoplasm; Female; Fluorouracil; Follow-Up Studies; Humans; Infusions, Intra-Arterial; Lung Neoplasms; Methotrexate; Pregnancy; Uterine Neoplasms; Vincristine | 1996 |
Meta-analyses of randomised trials: when the whole is more than just the sum of the parts.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Humans; Meta-Analysis as Topic; Methotrexate; Neoplasms; Ovarian Neoplasms; Proportional Hazards Models; Randomized Controlled Trials as Topic; Research Design | 1996 |
VIII. Women's health perception and breast cancer: issues of fertility, hormone substitution, and cancer prevention.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fertility; Fluorouracil; Humans; Menopause; Methotrexate; Pregnancy; Retrospective Studies; Risk; Treatment Outcome | 1996 |
Ocular toxicity following high dose chemotherapy and autologous transplant.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Demyelinating Diseases; Diagnosis, Differential; Doxorubicin; Fatal Outcome; Female; Fluorouracil; Hematopoietic Stem Cell Transplantation; Humans; Ischemia; Mastectomy, Modified Radical; Methotrexate; Middle Aged; Optic Nerve; Paraneoplastic Syndromes; Respiratory Insufficiency; Scotoma; Transplantation Conditioning; Visual Fields | 1996 |
Does dexamethasone leucocytosis facilitate full dosage adjuvant chemotherapy for breast cancer?
Topics: Adult; Antiemetics; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Dexamethasone; Drug Administration Schedule; Female; Fluorouracil; Glucocorticoids; Humans; Injections, Intravenous; Leukocytosis; Methotrexate; Premedication; Retrospective Studies | 1995 |
Positive selection and ex vivo expansion of hematopoietic progenitors as autografts for high-dose chemotherapy, potential importance in patients with bone metastases.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carmustine; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Hematopoietic Stem Cell Transplantation; Humans; Methotrexate; Neoplasm Staging; Remission Induction; Transplantation, Autologous | 1995 |
[A case of Borrmann type 4 gastric cancer successfully treated with MTX and 5-FU therapy through the hepatic artery].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Gastrectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Methotrexate; Stomach Neoplasms | 1996 |
[A case of non-resectable pancreatic cancer surviving more than 4 years by intra-arterial infusion chemotherapy with angiotensin-II].
Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ductal, Breast; Combined Modality Therapy; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Methotrexate; Middle Aged; Pancreatic Neoplasms; Survivors | 1996 |
Inefficient growth arrest in response to dNTP starvation stimulates gene amplification through bridge-breakage-fusion cycles.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Cell Division; Cell Line; Cloning, Molecular; Cricetinae; DNA Damage; Fluorouracil; Gene Amplification; Growth Inhibitors; Humans; In Situ Hybridization, Fluorescence; Methotrexate; Phosphonoacetic Acid; Pyrimidine Nucleotides; Tumor Cells, Cultured | 1996 |
Low-dose prednisone and increased risk of development of bone metastases.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Cisplatin; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Methotrexate; Prednisone | 1996 |
The influence of 5-fluorouracil and methotrexate on vascular endothelium. An experimental study using endothelial cells in the culture.
Topics: Animals; Antimetabolites, Antineoplastic; Cattle; Cell Survival; Cells, Cultured; Coronary Vessels; DNA; Endothelium, Vascular; Epoprostenol; Fluorouracil; Humans; Methotrexate; Models, Theoretical; Reference Values | 1996 |
Modulation of [5-125I]iododeoxyuridine incorporation into tumour and normal tissue DNA by methotrexate and thymidylate synthase inhibitors.
Topics: Animals; Antimetabolites, Antineoplastic; Dihydrouracil Dehydrogenase (NAD+); DNA, Neoplasm; Female; Fluorouracil; Idoxuridine; Intestine, Small; Iodine Radioisotopes; Liver; Mammary Neoplasms, Experimental; Methotrexate; Mice; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Quinazolines; Thiophenes; Thymidylate Synthase; Uracil | 1996 |
Persistence of chromosomal aberrations in blood lymphocytes 11 years after cessation of CMF therapy in a breast cancer patient.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chromosome Aberrations; Cisplatin; Female; Fluorouracil; Humans; Karyotyping; Lymphocytes; Methotrexate; Middle Aged; Time Factors | 1996 |
Exacerbation of rheumatoid arthritis after termination of chemotherapy for breast carcinoma.
Topics: Adenocarcinoma; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Recurrence | 1996 |
The hematological effects of folate analogs: implications for using the dihydrofolate reductase gene for in vivo selection.
Topics: Animals; Antimetabolites; Bone Marrow; Cells, Cultured; Femur; Fluorouracil; Genetic Therapy; Immunocompromised Host; Leukocytes, Mononuclear; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Spleen; Stem Cell Factor; Tetrahydrofolate Dehydrogenase; Trimetrexate | 1996 |
[Effective combined injection method of fluoropyrimidine and platinum--application for advanced esophageal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Drug Administration Schedule; Esophageal Neoplasms; Female; Fluorouracil; Humans; Injections; Male; Methotrexate; Vinblastine; Vindesine | 1996 |
p53 and PCNA expression in advanced colorectal cancer: response to chemotherapy and long-term prognosis.
Topics: Adult; Aged; Colorectal Neoplasms; Disease Progression; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunohistochemistry; Male; Methotrexate; Middle Aged; Multivariate Analysis; Proliferating Cell Nuclear Antigen; Retrospective Studies; Survival Analysis; Tumor Suppressor Protein p53 | 1996 |
A case of bone marrow recurrence from gastric carcinoma after a nine-year disease-free interval.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Carcinoma, Signet Ring Cell; Disseminated Intravascular Coagulation; Fluorouracil; Gastrectomy; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Radionuclide Imaging; Stomach Neoplasms | 1996 |
Small intestinal cancer with extensive lymph node metastases showing complete remission by methotrexate/5-fluorouracil sequential therapy: report of a case.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Humans; Intestinal Neoplasms; Lymphatic Metastasis; Methotrexate | 1997 |
Cell proliferation as a predictor of response to chemotherapy in metastatic breast cancer: a prospective study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Prospective Studies; Thymidine; Tumor Cells, Cultured | 1997 |
Influence of circulating c-erbB-2 serum protein on response to adjuvant chemotherapy in node-positive breast cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Case-Control Studies; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Mitoxantrone; Prognosis; Receptor, ErbB-2; Retrospective Studies; Survival Analysis | 1997 |
[A two-year asymptomatic case with postoperative lung metastasis of sigmoid colon cancer responding to sequential methotrexate and 5-fluorouracil].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Colon, Sigmoid; Drug Administration Schedule; Female; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Quality of Life; Sigmoid Neoplasms | 1997 |
[Combined breast-preserving surgery, chemotherapy and radiotherapy in the treatment of breast carcinoma. Effect of the interval between surgery and the beginning of radiotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Carcinoma, Medullary; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Postoperative Care; Prognosis; Radiotherapy Dosage; Retrospective Studies; Time Factors | 1997 |
[Histopathological and autoradiographical studies of experimental brain tumors after continuous local chemotherapy--acute stage in rat models].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autoradiography; Brain Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Glioma; Infusion Pumps; Male; Methotrexate; Rats; Rats, Inbred F344 | 1997 |
[New methods in the treatment of breast cancer].
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Diethylstilbestrol; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Randomized Controlled Trials as Topic; Retrospective Studies; Survival Analysis; Tamoxifen; Treatment Outcome | 1997 |
Direct injection of anti-cancer drugs into endobronchial tumours for palliation of major airway obstruction.
Topics: Adult; Aged; Aged, 80 and over; Airway Obstruction; Antineoplastic Agents; Bleomycin; Bronchial Neoplasms; Combined Modality Therapy; Debridement; Female; Fluorouracil; Humans; Injections, Intralesional; Male; Methotrexate; Middle Aged; Mitomycins; Mitoxantrone; Palliative Care | 1997 |
Induction chemotherapy with versus without hormonal synchronisation in locally advanced breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Disease Progression; Estrogens; Female; Fluorouracil; G1 Phase; Humans; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Remission Induction; Tamoxifen | 1997 |
Sequential intensive treatment with the F-MACHOP regimen (+/- radiotherapy) and autologous stem cell transplantation for primary systemic CD30 (Ki-1)--positive anaplastic large cell lymphoma in adults.
Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Cytarabine; Disease-Free Survival; Doxorubicin; Etoposide; Female; Fluorouracil; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma, Large-Cell, Anaplastic; Male; Methotrexate; Middle Aged; Prednisone; Prognosis; Prospective Studies; Remission Induction; Transplantation Conditioning; Transplantation, Autologous; Vincristine | 1997 |
[First-line chemotherapy in operable breast neoplasms: results of 3 protocols].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Retrospective Studies; Treatment Outcome; Vinblastine; Vincristine; Vinorelbine | 1997 |
Insulin-like growth factor 1 (IGF-1) alters drug sensitivity of HBL100 human breast cancer cells by inhibition of apoptosis induced by diverse anticancer drugs.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Northern; Blotting, Western; Breast Neoplasms; Camptothecin; Cell Survival; Collagen; Drug Combinations; Extracellular Matrix; Female; Fluorouracil; Humans; Insulin-Like Growth Factor I; Laminin; Methotrexate; Microscopy, Electron; Proteoglycans; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tamoxifen; Time Factors; Tumor Cells, Cultured | 1997 |
Weekly chronomodulated 48 h infusion of high-dose 5-fluorouracil modulated by methotrexate and (6S)-leucovorin in advanced colorectal cancer: a phase IB study.
Topics: Adenocarcinoma; Adult; Aged; Antidotes; Antimetabolites, Antineoplastic; Clinical Trials, Phase I as Topic; Colorectal Neoplasms; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged; Time Factors | 1997 |
Transforming growth factor-beta1 enhances the lethal effects of DNA-damaging agents in a human lung-cancer cell line.
Topics: Animals; Antineoplastic Agents; Cell Death; Cisplatin; DNA Damage; Drug Synergism; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Transforming Growth Factor beta; Tumor Cells, Cultured | 1997 |
Inhibition of growth in oral squamous carcinoma cells by cyclopentenone prostaglandins: comparison with chemotherapeutic agents.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Dinoprostone; Fluorouracil; Humans; Methotrexate; Mouth Neoplasms; Prostaglandin D2; Prostaglandins A; Prostaglandins A, Synthetic; Prostaglandins, Synthetic; Tocopherols; Tumor Cells, Cultured; Vitamin E | 1997 |
Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell death.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-X Protein; Clone Cells; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Gamma Rays; Genes, bcl-2; Humans; Hydroxyurea; Methotrexate; Mice; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; S Phase; Teniposide; Transfection; Vincristine | 1997 |
Cross-resistance to antifolates in multidrug resistant cell lines with P-glycoprotein or multidrug resistance protein expression.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Division; Drug Resistance, Multiple; Fluorodeoxyuridylate; Fluorouracil; Folic Acid Antagonists; Gene Expression Regulation; Humans; Indoles; Isoindoles; Methotrexate; Peptide Synthases; Polymerase Chain Reaction; Quinazolines; RNA, Messenger; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured | 1997 |
Pharmacokinetic monitoring of anticancer drugs at King Faisal Specialist Hospital, Riyadh, Saudi Arabia.
Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Doxorubicin; Etoposide; Fluorouracil; Humans; Methotrexate; Mitoxantrone; Reference Values; Saudi Arabia | 1997 |
Immunocytochemical detection of P-glycoprotein in the management of malignant effusions.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bleomycin; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Exudates and Transudates; Female; Fluorouracil; Humans; Immunohistochemistry; Methotrexate; Ovarian Neoplasms; Pleural Effusion | 1997 |
Effectiveness of selective neck dissection for management of the clinically negative neck.
Topics: Adult; Aged; Aged, 80 and over; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Decision Making; Disease-Free Survival; Elective Surgical Procedures; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Lymph Node Excision; Lymph Nodes; Methotrexate; Middle Aged; Neck; Neck Dissection; Neoplasm Recurrence, Local; Neoplasm Staging; Radiotherapy, Adjuvant; Retrospective Studies; Treatment Outcome | 1997 |
The role of radiation therapy and chemotherapy in the treatment of Merkel cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Merkel Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasms, Multiple Primary; Prognosis; Radiotherapy, High-Energy; Retrospective Studies; Skin Neoplasms; Survival Analysis; Treatment Outcome; Vincristine | 1997 |
[A case of papillary adenocarcinoma of the stomach with liver metastases and carcinomatous peritonitis treated effectively by methotrexate/5-fluorouracil sequential chemotherapy].
Topics: Adenocarcinoma, Papillary; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Administration Schedule; Fluorouracil; Humans; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Peritonitis; Stomach Neoplasms | 1997 |
Modulation of 5-fluorouracil with methotrexate and low-dose N-(phosphonacetyl)-L-aspartate (PALA) is inactive in advanced pancreatic carcinoma.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Phosphonoacetic Acid | 1997 |
Chemotherapy is a safe and effective initial therapy for infected malignant breast and chest wall ulcers.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Retrospective Studies; Skin Ulcer; Thorax | 1997 |
[Preoperative irradiation and interstitial radiotherapy-hyperthermia boost in breast tumors > or = 3 cm. The Düsseldorf experience].
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Hyperthermia, Induced; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Preoperative Care; Radiotherapy Dosage; Surgical Flaps; Time Factors | 1997 |
[A case report of preoperative intra-arterial infusion chemotherapy for pancreatic head carcinoma].
Topics: Adenocarcinoma; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Vasoconstrictor Agents | 1997 |
[Experimental study on intraperitoneal sequential MTX/5-FU therapy for peritoneal seeding in comparison with intravenous administration].
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intravenous; Infusions, Parenteral; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Peritoneal Neoplasms; Stomach Neoplasms | 1997 |
Feasibility of adjuvant chemotherapy for breast cancer patients.
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Constipation; Cyclophosphamide; Cystitis; Doxorubicin; Drug Administration Schedule; Exanthema; Feasibility Studies; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Pyrimidines | 1997 |
Clinical prognostic and predictive factors for primary chemotherapy in operable breast cancer.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cisplatin; Disease Progression; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Methotrexate; Middle Aged; Mitomycin; Mitoxantrone; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Treatment Outcome | 1998 |
Ethics of randomized clinical trials.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Cisplatin; Comprehension; Cyclophosphamide; Disclosure; Doxorubicin; Ethical Theory; Ethics, Medical; Female; Fluorouracil; Humans; Methotrexate; Paclitaxel; Patient Advocacy; Personal Autonomy; Physician-Patient Relations; Professional-Family Relations; Prognosis; Randomized Controlled Trials as Topic; Researcher-Subject Relations; Risk Assessment; Therapeutic Human Experimentation; Uncertainty | 1998 |
Radiotherapy and chemotherapy in high-risk breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Mastectomy; Methotrexate | 1998 |
[A case of advanced gastric cancer with multiple bone metastasis successfully treated by both methotrexate and 5-fluorouracil sequential therapy, and endoscopic intratumoral injection of 5-fluorouracil].
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Drug Administration Schedule; Fluorouracil; Gastroscopy; Humans; Injections, Intralesional; Male; Methotrexate; Stomach Neoplasms | 1998 |
Making TDM work to optimize cancer chemotherapy: a multidisciplinary team approach.
Topics: Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Monitoring; Fluorouracil; Humans; Mercaptopurine; Methotrexate; Neoplasms; Outcome Assessment, Health Care | 1998 |
Adjuvant cyclophosphamide, methotrexate and fluorouracil for node-positive breast cancer: a lifetime cost-utility analysis based on a modified Q-TWIST method.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate | 1997 |
[Resuscitation necessitated by a transfusion reaction after HLA mismatched platelets substitution].
Topics: Anaphylaxis; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Cytotoxicity, Immunologic; Female; Fluorouracil; Heart Arrest; Histocompatibility Testing; HLA Antigens; Humans; Isoantibodies; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Neoplasms, Second Primary; Platelet Transfusion; Resuscitation | 1994 |
Conservative surgery and radiotherapy in early stage breast cancer: a comparison between tumourectomy and quadrantectomy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Radiotherapy, Adjuvant; Retrospective Studies; Survival Rate | 1998 |
Frequent dose delays and growth factor requirements with the sequential doxorubicin-CMF schedule.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Growth Substances; Humans; Methotrexate; Middle Aged | 1997 |
[Successful chemotherapy based on in vitro chemosensitivity testing in a case of recurrent thymic carcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Adenosquamous; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Recurrence, Local; Thymus Neoplasms; Tumor Cells, Cultured | 1998 |
Resistance to high concentrations of methotrexate and 5-fluorouracil of differentiated HT-29 colon-cancer cells is restricted to cells of enterocytic phenotype.
Topics: Antimetabolites, Antineoplastic; Cell Differentiation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; HT29 Cells; Humans; Methotrexate; Phenotype; Tetrahydrofolate Dehydrogenase | 1998 |
Retreating recurrent breast cancer with the same CMF-containing regimen used as adjuvant therapy. The International Breast Cancer Study Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Prospective Studies; Survival Analysis; Tamoxifen; Time Factors; Treatment Outcome | 1997 |
[Chemotherapy repeated injection via pelvic retroperitoneal cannulation].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Catheters, Indwelling; Dogs; Endometrial Neoplasms; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Ovarian Neoplasms; Pelvis; Random Allocation; Retroperitoneal Space; Thiotepa | 1997 |
Combination of cisplatin-procaine complex DPR with anticancer drugs increases cytotoxicity against ovarian cancer cell lines.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Microtubules; Mitomycin; Organoplatinum Compounds; Ovarian Neoplasms; Paclitaxel; Procaine; Tumor Cells, Cultured | 1998 |
Plasma c-erbB-2 levels in breast cancer patients: prognostic significance in predicting response to chemotherapy.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Predictive Value of Tests; Prednisone; Prognosis; Receptor, ErbB-2; Treatment Outcome; Vincristine | 1998 |
Sensitization of human bladder cancer cells to Fas-mediated cytotoxicity by cis-diamminedichloroplatinum (II).
Topics: Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Carcinoma, Transitional Cell; Cell Death; Cisplatin; Cytotoxicity, Immunologic; Drug Resistance, Neoplasm; fas Receptor; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Immunization; Immunotherapy; Indicators and Reagents; Killer Cells, Natural; Methotrexate; Mitomycin; T-Lymphocytes, Cytotoxic; Tetrazolium Salts; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1998 |
[Evaluation of intra-arterial infusion chemotherapy for advanced gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Lymphatic Metastasis; Methotrexate; Middle Aged; Mitomycin; Prognosis; Stomach Neoplasms; Survival Analysis | 1998 |
[Intraarterial chemotherapy via reservoir system for far-advanced bladder and prostate cancer].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Prostatic Neoplasms; Urinary Bladder Neoplasms | 1998 |
[Pharmaco-dynamic influence under ascites or laparotomy on intraperitoneal sequential MTX/5-FU therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Fluorouracil; Gastrectomy; Humans; Infusions, Parenteral; Methotrexate; Peritoneal Neoplasms; Stomach Neoplasms | 1998 |
A patient with breast cancer and paraneoplastic cerebellar syndrome associated with anti-Purkinje cell antibodies: response to CMF chemotherapy.
Topics: Adult; Antibodies; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Medullary; Cerebellar Ataxia; Cyclophosphamide; Female; Fluorouracil; Humans; Immunosuppressive Agents; Methotrexate; Ovary; Paraneoplastic Syndromes; Purkinje Cells | 1998 |
Luteinizing hormone-releasing hormone analogues in early breast cancer: updated status of ongoing clinical trials.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Goserelin; Humans; Meta-Analysis as Topic; Methotrexate; Premenopause; Tamoxifen | 1998 |
The place of chemotherapy in the treatment of early breast cancer.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Postmenopause; Premenopause; Receptors, Estrogen; Tamoxifen | 1998 |
[Membranous lipodystrophy caused by chemotherapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lipodystrophy; Liver Neoplasms; Methotrexate | 1998 |
The presence of proliferative breast disease with atypia does not significantly influence outcome in early-stage invasive breast cancer treated with conservative surgery and radiation.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Estrogen Replacement Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Hyperplasia; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Precancerous Conditions; Radiotherapy Dosage; Survival Analysis | 1998 |
Heat shock protein expression and drug resistance in breast cancer patients treated with induction chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Breast Neoplasms; Cell Division; Cisplatin; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Drug Resistance, Neoplasm; Epirubicin; Fluorouracil; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Methotrexate; Middle Aged; Nucleolus Organizer Region; Prognosis; Proliferating Cell Nuclear Antigen; Silver Staining | 1998 |
[Thymic anaplastic carcinoma successfully controlled by combination chemotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Male; Methotrexate; Thymus Neoplasms; Treatment Outcome | 1998 |
Expression of bcl-2 protein predicts efficacy of adjuvant treatments in operable node-positive breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Follow-Up Studies; Genes, bcl-2; Humans; Lymphatic Metastasis; Menopause; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Staging; Predictive Value of Tests; Prognosis; Proto-Oncogene Mas; Proto-Oncogene Proteins c-bcl-2; Survival Rate; Tamoxifen; Time Factors | 1995 |
An audit of antiemetic use with CMF chemotherapy.
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Drug Therapy, Combination; Female; Fluorouracil; Granisetron; Humans; Medical Records; Methotrexate; Metoclopramide; Retrospective Studies; Serotonin Antagonists; Treatment Outcome; Vomiting | 1998 |
Adjuvant chemotherapy with CEF versus CMF for node-positive breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Cytarabine; Epirubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Proportional Hazards Models; Randomized Controlled Trials as Topic; Research Design | 1998 |
[Nursing situation in outpatient chemotherapy following surgery for gastric cancer].
Topics: Adenocarcinoma; Adult; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Male; Methotrexate; Middle Aged; Postoperative Care; Stomach Neoplasms | 1998 |
Dose-response effect of adjuvant cyclophosphamide, methotrexate, 5-fluorouracil (CMF) in node-positive breast cancer. International Breast Cancer Study Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Postmenopause; Premenopause; Retrospective Studies | 1998 |
Primary chemotherapy in locally advanced breast cancer (LABC): effects on tumour proliferative activity, bcl-2 expression and the relationship between tumour regression and biological markers.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Division; Cyclophosphamide; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Genes, bcl-2; Humans; Immunohistochemistry; Methotrexate; Middle Aged; Prognosis | 1998 |
Extracellular glutamine level reduction enhances 5-fluorouracil cytotoxicity.
Topics: Amino Acids; Animals; Asparagine; Cell Count; Dose-Response Relationship, Drug; Fluorouracil; Glutamine; Humans; Leukemia; Leukemia P388; Methotrexate; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured | 1998 |
Intensified adjuvant cyclophosphamide, methotrexate and 5-fluorouracil therapy: a dose-finding study for ambulatory patients with breast cancer.
Topics: Adult; Aged; Agranulocytosis; Alopecia; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Conjunctivitis; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Gastrointestinal Diseases; Granulocyte Colony-Stimulating Factor; Humans; Methotrexate; Middle Aged; Neutropenia; Treatment Outcome; Urinary Bladder | 1999 |
[A case of unresectable pancreatic cancer responding to MTX/5-FU sequential therapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Pancreatic Neoplasms; Quality of Life | 1999 |
Angiogenesis vs. response after combined chemoradiotherapy of squamous cell head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neovascularization, Pathologic; Oxygen; Pilot Projects; Remission Induction; Survival Analysis; Treatment Outcome | 1999 |
The use of neoadjuvant CMF to avoid mastectomy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Neoplasm Staging; Remission Induction; Treatment Outcome | 1999 |
Volume localized in vivo proton MR spectroscopy of breast carcinoma: variation of water-fat ratio in patients receiving chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Cyclophosphamide; Doxorubicin; Fats; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoadjuvant Therapy; Nuclear Magnetic Resonance, Biomolecular; Water | 1998 |
Evaluation of individual sensitivity to cytostatic drugs of in vitro cultured lung tumor cells.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bleomycin; Carcinoma, Non-Small-Cell Lung; Cell Division; Cisplatin; Epirubicin; Etoposide; Fluorouracil; Lung Neoplasms; Methotrexate; Tumor Cells, Cultured; Vinblastine; Vincristine | 1999 |
Comparative analysis of breast cancer recurrence risk for patients receiving or not receiving adjuvant cyclophosphamide, methotrexate, fluorouracil (CMF). Data supporting the occurrence of 'cures'.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Incidence; Logistic Models; Mastectomy, Radical; Methotrexate; Recurrence; Retrospective Studies; Risk Assessment; Survival Analysis; Survival Rate; Time Factors | 1999 |
Metaplastic breast cancer: prognosis and response to systemic therapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Disease Progression; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Metaplasia; Methotrexate; Middle Aged; Neoplasms, Complex and Mixed; Palliative Care; Prognosis; Radiotherapy, Adjuvant; Retrospective Studies; Severity of Illness Index; Survival Rate; Tamoxifen; Treatment Outcome | 1999 |
Penetration of anticancer drugs through solid tissue: a factor that limits the effectiveness of chemotherapy for solid tumors.
Topics: Animals; Antineoplastic Agents; Biological Availability; Diffusion; Diffusion Chambers, Culture; Doxorubicin; Fluorouracil; Humans; Methotrexate; Mice; Mitoxantrone; Neoplasms, Experimental; Time Factors; Tumor Cells, Cultured | 1999 |
[A case of type 4 gastric cancer with peritoneal dissemination treated with intra-aortic chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Leucovorin; Methotrexate; Middle Aged; Peritoneal Neoplasms; Stomach Neoplasms | 1999 |
[A case of liver metastases from gastric cancer responding to induced hypertensive chemotherapy with angiotensin II].
Topics: Aged; Angiotensin II; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Injections, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Methotrexate; Mitomycin; Neoplasm Recurrence, Local; Stomach Neoplasms; Vasoconstrictor Agents | 1999 |
Quality of adjuvant chemotherapy in primary breast cancer in a non-trial setting. A comprehensive cancer centre study. The Breast Cancer Group of the Dutch Comprehensive Cancer Centre East (IKO).
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Humans; Methotrexate; Patient Compliance; Quality of Health Care; Retrospective Studies | 1999 |
Estradiol receptor and prognostic parameters of human breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Receptors, Estradiol; Tamoxifen | 1999 |
Expression of C-erbB-2/HER-2 in patients with metastatic breast cancer undergoing high-dose chemotherapy and autologous blood stem cell support.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Epirubicin; Female; Fluorouracil; Hematopoietic Stem Cell Transplantation; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Receptor, ErbB-2; Retrospective Studies; Survival Analysis; Transplantation, Autologous | 1999 |
The leucocyte nadir, a predictor of chemotherapy efficacy?
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Monitoring; Female; Fluorouracil; Humans; Leukocyte Count; Leukopenia; Methotrexate; Neoplasms; Predictive Value of Tests | 1999 |
[The effect of the parameters of the therapeutic protocol on the efficacy of the adjuvant chemotherapy of breast cancer].
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Protocols; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Staging; Postoperative Care; Retrospective Studies; Thiotepa | 1999 |
Reduced expression of p27Kip1 protein is associated with poor clinical outcome of breast cancer patients treated with systemic chemotherapy and is linked to cell proliferation and differentiation.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell Division; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclin-Dependent Kinase Inhibitor p27; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Mastectomy; Methotrexate; Microtubule-Associated Proteins; Middle Aged; Neoplasm Metastasis; Neoplasm Proteins; Ploidies; Receptors, Estrogen; Receptors, Progesterone; Risk Factors; Survival Analysis; Tumor Suppressor Proteins | 1999 |
Comparison of the effects of various anticancer agents on intestinal anastomosis after intraperitoneal administration.
Topics: Analysis of Variance; Anastomosis, Surgical; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cisplatin; Doxorubicin; Fluorouracil; Injections, Intraperitoneal; Intestine, Small; Male; Methotrexate; Rats; Rats, Wistar; Statistics, Nonparametric; Weight Loss; Wound Healing | 1999 |
Brain metastases in breast cancer: prognostic factors and management.
Topics: Adult; Age Distribution; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Cisplatin; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Postmenopause; Premenopause; Prognosis; Retrospective Studies; Survival Analysis | 1999 |
The therapy of primary adult systemic CD30-positive anaplastic large cell lymphoma: results of 40 cases treated in a single center.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Fluorouracil; Humans; Lymphoma, Large-Cell, Anaplastic; Male; Methotrexate; Middle Aged; Prednisone; Radiotherapy, Adjuvant; Retrospective Studies; Treatment Outcome; Vincristine | 1999 |
Impact of oral submucous fibrosis on chemotherapy-induced mucositis for head and neck cancer in a geographic area in which betel quid chewing is prevalent.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Areca; Asia, Southeastern; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Oral Submucous Fibrosis; Plants, Medicinal; Stomatitis; Taiwan | 1999 |
[Pharmaco-dynamic study of methotrexate (MTX) during intraperitoneal MTX/5-FU sequential therapy after gastric surgery].
Topics: Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Infusions, Parenteral; Methotrexate; Postoperative Care; Stomach Neoplasms | 1999 |
[A case report of hepatocellular carcinoma with hepatic and portal venous tumor thrombus and multiple intrahepatic metastasis who survived over 1 year after the operation with combined locoregional chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Embolization, Therapeutic; Fluorouracil; Hepatectomy; Humans; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Methotrexate; Neoplasm Invasiveness; Neoplastic Cells, Circulating; Portal Vein | 1999 |
Risk of menopause during the first year after breast cancer diagnosis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Cytarabine; Epirubicin; Female; Fluorouracil; Humans; Mastectomy; Menopause, Premature; Methotrexate; Middle Aged; Multivariate Analysis; Premenopause; Probability; Risk Factors; Tamoxifen | 1999 |
Intra-arterial infusion chemotherapy for penile carcinoma with deep inguinal lymph node metastasis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intra-Arterial; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Penile Neoplasms | 1999 |
Recurrent inflammation in a site of previous necrotising fasciitis during intravenous CMF chemotherapy.
Topics: Abdomen; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cicatrix; Cyclophosphamide; Fasciitis, Necrotizing; Female; Fluorouracil; Humans; Inflammation; Methotrexate; Middle Aged | 1999 |
Overexpression of Bcl-x(L) promotes chemotherapy resistance of mammary tumors in a syngeneic mouse model.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Apoptosis; bcl-X Protein; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fluorouracil; Gene Expression; Mammary Neoplasms, Experimental; Methotrexate; Mice; Neoplasm Transplantation; Proto-Oncogene Proteins c-bcl-2; Transfection; Tumor Cells, Cultured | 1999 |
Treatment of mammographically detected minimal breast cancer in an older woman.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Mammography; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy; Tamoxifen | 2000 |
Changes in body composition during breast cancer chemotherapy with the CMF-regimen.
Topics: Adult; Aged; Anthropometry; Antineoplastic Combined Chemotherapy Protocols; Body Composition; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Stress, Psychological; Weight Gain | 1999 |
Commentary on PBT-1 study of high-dose consolidation versus standard therapy in metastatic breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Fluorouracil; Hematopoietic Stem Cell Transplantation; Humans; Methotrexate; Neoplasm Metastasis; Randomized Controlled Trials as Topic; South Africa; Time Factors; United States | 1999 |
Hepatic toxicity from cyclophosphamide, methotrexate, fluorouracil (CMF regimen)
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Liver; Liver Function Tests; Methotrexate; Retrospective Studies; Risk Assessment | 1999 |
How women receiving adjuvant chemotherapy for breast cancer cope with their treatment: a risk management perspective.
Topics: Adaptation, Psychological; Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; England; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Risk Factors; Risk Management; Time Factors | 2000 |
Tumor markers CEA, CA19-9 and CA125 in monitoring of response to systemic chemotherapy in patients with advanced gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; CA-125 Antigen; CA-19-9 Antigen; Camptothecin; Carcinoembryonic Antigen; Cisplatin; Female; Fluorouracil; Humans; Irinotecan; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Prognosis; Sensitivity and Specificity; Stomach Neoplasms; Survival Rate | 1999 |
[A case of diffusely infiltrating carcinoma of the sigmoid colon associated with lymphangitis carcinomatosa effectively treated with sequential MTX.5-FU and 5'-DFUR].
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Floxuridine; Fluorouracil; Humans; Lymphangitis; Male; Methotrexate; Sigmoid Neoplasms | 2000 |
Enhancement of 5-fluorouracil anabolism by methotrexate and trimetrexate in two rat solid tumor models, Walker 256 carcinosarcoma and Novikoff hepatoma, as evaluated by 19F-magnetic resonance spectroscopy.
Topics: Animals; Carcinoma 256, Walker; Drug Administration Schedule; Fluorine; Fluorouracil; Kinetics; Liver Neoplasms, Experimental; Magnetic Resonance Spectroscopy; Male; Methotrexate; Rats; Rats, Sprague-Dawley; Trimetrexate | 2000 |
ACNU, MTX and 5-FU penetration of rat brain tissue and tumors.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Autoradiography; Brain; Female; Fluorouracil; Meningeal Neoplasms; Methotrexate; Nimustine; Rats; Rats, Wistar; Reference Values | 1999 |
[Predictive chemotherapy of breast cancer directed by MTT assay in vitro].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Coloring Agents; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Methotrexate; Prospective Studies; Tetrazolium Salts; Thiazoles | 1997 |
Incidence and time of occurrence of regional recurrence in stage I-II breast cancer: value of adjuvant irradiation.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cisplatin; Female; Fluorouracil; Follow-Up Studies; Humans; Incidence; Lymph Node Excision; Lymph Nodes; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Radiotherapy, Adjuvant; Retrospective Studies; Risk Factors; Time Factors; Treatment Failure | 1999 |
Accelerated superfractionated radiotherapy for inflammatory breast carcinoma: complete response predicts outcome and allows for breast conservation.
Topics: Adenocarcinoma; Adult; Aged; Breast Neoplasms; Carcinoma, Ductal, Breast; Combined Modality Therapy; Cyclophosphamide; Decision Trees; Disease-Free Survival; Dose Fractionation, Radiation; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Methotrexate; Middle Aged; Prospective Studies; Remission Induction; Treatment Failure | 1999 |
Anthracyclines trigger apoptosis of both G0-G1 and cycling peripheral blood lymphocytes and induce massive deletion of mature T and B cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; B-Lymphocytes; Camptothecin; Cell Cycle; Cells, Cultured; Daunorubicin; Doxorubicin; Etoposide; Fluorouracil; G1 Phase; Humans; Lymph Nodes; Lymphocyte Depletion; Lymphocytes; Methotrexate; Mice; Mice, Inbred BALB C; Resting Phase, Cell Cycle; Spleen; T-Lymphocytes; Thymus Gland | 2000 |
Influence of adjuvant chemotherapy with cyclophosphamide, methotrexate and 5-fluorouracil on plasma insulin-like growth factor-I and chosen hormones in breast cancer pre-menopausal patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Estradiol; Female; Fluorouracil; Humans; Hydrocortisone; Insulin-Like Growth Factor I; Melatonin; Methotrexate; Middle Aged; Premenopause; Progesterone; Prolactin | 2000 |
A phase II trial of methotrexate, cisplatin, 5-fluorouracil, and leucovorin in the treatment of invasive and metastatic urothelial carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials, Phase II as Topic; Fluorouracil; Humans; Leucovorin; Methotrexate; Neoplasm Invasiveness; Neoplasm Metastasis; Urologic Neoplasms | 2000 |
MTHFR gene polymorphism and severe toxicity during adjuvant treatment of early breast cancer with cyclophosphamide, methotrexate, and fluorouracil (CMF)
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic | 2000 |
Plasminogen activator proteins tested as prognostic markers.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Enzyme-Linked Immunosorbent Assay; Female; Fluorouracil; Germany; Humans; Methotrexate; Multicenter Studies as Topic; Odds Ratio; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Predictive Value of Tests; Prognosis; Prospective Studies; Serine Proteinase Inhibitors; Time Factors; Treatment Outcome; Urokinase-Type Plasminogen Activator | 2000 |
Chemosensitivity of advanced larynx carcinoma cells in vitro and significance of multidrug resistance markers in these tumors.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers, Tumor; Cell Survival; Cisplatin; Drug Resistance, Multiple; Fluorouracil; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Humans; Laryngeal Neoplasms; Lymphatic Metastasis; Methotrexate; Mitomycin; Neoplasm Metastasis; Neoplasm Staging; Protein Kinase C; Tumor Cells, Cultured | 1998 |
Effects of c-erbB2 overexpression on the drug sensitivities of normal human mammary epithelial cells.
Topics: Antineoplastic Agents; Blotting, Western; Breast; Cells, Cultured; Cisplatin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epithelial Cells; Female; Flavonoids; Flow Cytometry; Fluorouracil; Genes, erbB-2; Humans; Methotrexate; Paclitaxel; Phosphorylation; Piperidines; Receptor, ErbB-2; Transduction, Genetic; Transfection; Up-Regulation | 2000 |
Feasibility of a dose-intensive CMF regimen with granulocyte colony-stimulating factor as adjuvant therapy in premenopausal patients with node-positive breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Feasibility Studies; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Prospective Studies | 2000 |
Wide-field radiation as adjunct to adjuvant chemotherapy in high-risk cases with early breast cancer: do it or not?
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cause of Death; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy, Modified Radical; Meta-Analysis as Topic; Methotrexate; Neoplasm Recurrence, Local; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Risk; Treatment Failure; Treatment Outcome | 2000 |
[Quality outcome of adjuvant CMF therapy in patients with breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Premenopause | 2000 |
Simultaneous adjuvant radiotherapy and chemotherapy for stage I and II breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Time Factors; Treatment Outcome | 1999 |
p53 but not bcl-2 immunostaining is predictive of poor clinical complete response to primary chemotherapy in breast cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Immunohistochemistry; Methotrexate; Middle Aged; Neoplasm Staging; Predictive Value of Tests; Proto-Oncogene Proteins c-bcl-2; Receptor, ErbB-2; Tamoxifen; Treatment Outcome; Tumor Suppressor Protein p53 | 2000 |
[Cox proportion hazard model multivariate analysis of prognosis of 1,484 axillary node-negative breast cancer patients].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Mastectomy; Methotrexate; Middle Aged; Multivariate Analysis; Prognosis; Proportional Hazards Models; Radiotherapy, Adjuvant | 1997 |
Relationship between in vivo drug exposure of the tumor interstitium and inhibition of tumor cell growth in vitro: a study in breast cancer patients.
Topics: Antimetabolites, Antineoplastic; Area Under Curve; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Male; Methotrexate; Models, Biological; Tumor Cells, Cultured | 2000 |
Alterations in laboratory test results during adjuvant breast cancer treatment.
Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Blood Proteins; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Chemistry Tests; Cyclophosphamide; Diagnosis, Differential; Female; Fluorouracil; Follow-Up Studies; Hematologic Tests; Hormones; Humans; Lipids; Methotrexate; Middle Aged; Reference Values | 2000 |
Predictive value of p53, mdm-2, p21, and mib-1 for chemotherapy response in advanced breast cancer.
Topics: Adolescent; Adult; Aged; Antigens, Nuclear; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Docetaxel; Female; Fluorouracil; Humans; Immunohistochemistry; Ki-67 Antigen; Methotrexate; Middle Aged; Multicenter Studies as Topic; Neoplasm Proteins; Nuclear Proteins; Paclitaxel; Paraffin Embedding; Predictive Value of Tests; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Randomized Controlled Trials as Topic; Taxoids; Tumor Suppressor Protein p53 | 2000 |
[High-dose chemotherapy for metastatic breast cancer without certain advantages so far].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Remission Induction; Thiotepa; Treatment Outcome | 2000 |
Plasma transforming growth factor beta1 in breast cancer patients treated with CMF chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Premenopause; Prognosis; Transforming Growth Factor beta | 2000 |
Local recurrence after mastectomy and adjuvant CMF: implications for adjuvant radiation therapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy, Radical; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy, Adjuvant; Retrospective Studies; Survival Rate; Treatment Outcome | 2000 |
Breast carcinoma in young patients.
Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Survival Analysis | 2000 |
Breast carcinoma in young patients.
Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Reproductive History; Survival Analysis | 2000 |
Tubulocystic clear cell adenocarcinoma arising within the prostate.
Topics: Adenocarcinoma, Clear Cell; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Fluorouracil; Humans; Immunohistochemistry; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Proteins; Prostatic Neoplasms; Testicular Neoplasms | 2000 |
Postsurgical sequential methotrexate, fluorouracil, and leucovorin for stages 3 and 4 gastric carcinoma: A preliminary study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Fluorouracil; Gastrectomy; Humans; Leucovorin; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Stomach Neoplasms; Survival Rate; Tegafur; Uracil | 2000 |
Experience of neoadjuvant chemotherapy for breast cancer at a public hospital: retrospective study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Hong Kong; Hospitals, Public; Humans; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Retrospective Studies; Treatment Outcome | 2000 |
Tamoxifen-induced severe hypertriglyceridemia and pancreatitis.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Female; Fluorouracil; Humans; Hypertriglyceridemia; Methotrexate; Middle Aged; Pancreatitis; Tamoxifen | 2000 |
[Two bedridden patients with bone metastases from breast cancer effectively treated with pamidronate therapy].
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Diphosphonates; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Pamidronate | 2000 |
The tumour suppressor protein p53 can repress transcription of cyclin B.
Topics: Cyclin B; Cyclin B1; Cyclin B2; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Luciferases; Methotrexate; Mutation; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
Depression and degree of acceptance of adjuvant cytotoxic drugs.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Case-Control Studies; Chemotherapy, Adjuvant; Cyclophosphamide; Depression; Drug Administration Schedule; Female; Fluorouracil; Humans; Logistic Models; Methotrexate; Middle Aged; Patient Acceptance of Health Care; Retrospective Studies | 2000 |
ECF in gastric cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Epirubicin; Fluorouracil; Humans; Methotrexate; Randomized Controlled Trials as Topic; Stomach Neoplasms | 2000 |
Surrogate endpoints for new colorectal cancer drugs.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Floxuridine; Fluorouracil; Humans; Leucovorin; Methotrexate; Randomized Controlled Trials as Topic; Survival Analysis | 2000 |
The use of millimeter band electromagnetic waves in clinical oncology.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Breast Neoplasms; Cyclophosphamide; Electromagnetic Fields; Female; Fluorouracil; Humans; Medical Oncology; Melanoma; Methotrexate; Radiotherapy, Adjuvant; Skin Neoplasms; Wound Healing | 2000 |
HER2 and choice of adjuvant chemotherapy for invasive breast cancer: National Surgical Adjuvant Breast and Bowel Project Protocol B-15.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Methotrexate; Middle Aged; Receptor, ErbB-2; Retrospective Studies; Risk; Survival Analysis; Treatment Outcome; Up-Regulation | 2000 |
Optimal control for a stochastic model of cancer chemotherapy.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Computer Simulation; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Methotrexate; Models, Biological; Stochastic Processes | 2000 |
Implications for improved high-dose methotrexate therapeutic effects in cultured human breast cancer and bone marrow cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Breast Neoplasms; Cell Line; Dose-Response Relationship, Drug; Drug Administration Schedule; Fluorouracil; Folic Acid Antagonists; Humans; Methotrexate; Trimetrexate; Tumor Cells, Cultured | 2000 |
Polyadenylic-polyuridylic acid plus locoregional radiotherapy versus chemotherapy with CMF in operable breast cancer: a 14 year follow-up analysis of a randomized trial of the Fédération Nationale des Centres de Lutte contre le Cancer (FNCLCC).
Topics: Adjuvants, Immunologic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Poly A-U; Radiotherapy, Adjuvant | 2000 |
Sample size calculations for the two-sample problem using the multiplicative intensity model.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Child; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Fluoxymesterone; Granulomatous Disease, Chronic; Humans; Interferon-gamma; Likelihood Functions; Markov Chains; Methotrexate; Models, Biological; Prednisone; Randomized Controlled Trials as Topic; Sample Size; Tamoxifen | 2001 |
Synergistic efficacy of 3n-butyrate and 5-fluorouracil in human colorectal cancer xenografts via modulation of DNA synthesis.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers; Butyrates; Cell Differentiation; Cell Division; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); DNA; Drug Synergism; Female; Fluorouracil; Glucose; Humans; Liver Neoplasms; Male; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Organoplatinum Compounds; Oxaliplatin; Oxidoreductases; Protein-Tyrosine Kinases; Quinazolines; RNA, Messenger; Thiophenes; Thymidylate Synthase; Transplantation, Heterologous | 2001 |
Expression of apoptosis-related markers and clinical outcome in patients with advanced colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Biomarkers, Tumor; Colorectal Neoplasms; Fluorouracil; Humans; Immunohistochemistry; Leucovorin; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Survival Rate; Treatment Outcome; Tumor Suppressor Protein p53 | 2001 |
Alleviation by garlic of antitumor drug-induced damage to the intestine.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Dextrans; Fluorescein-5-isothiocyanate; Fluorouracil; Garlic; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Male; Methotrexate; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar | 2001 |
Angiogenesis sustains tumor dormancy in patients with breast cancer treated with adjuvant chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Methotrexate; Microcirculation; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Prognosis; Risk Factors | 2001 |
Effect of obesity on the leukocyte nadir in women treated with adjuvant cyclophosphamide, methotrexate, and fluorouracil dosed according to body surface area.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Body Constitution; Body Mass Index; Body Surface Area; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Leukocyte Count; Leukopenia; Methotrexate; Middle Aged; Obesity | 2001 |
Dose-dense sequential adjuvant chemotherapy with epirubicin, paclitaxel and CMF in high-risk breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Paclitaxel; Risk | 2001 |
Anticancer drugs as inducers of thermotolerance in yeast.
Topics: Antineoplastic Agents; Bleomycin; Camptothecin; Cisplatin; Dose-Response Relationship, Drug; Fluorouracil; Hot Temperature; Irinotecan; Methotrexate; Mitomycin; Saccharomyces | 2000 |
A preclinical model for experimental chemotherapy of human head and neck cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Body Weight; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Disease Models, Animal; Docetaxel; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Ifosfamide; Methotrexate; Mice; Mice, Nude; Paclitaxel; Survival Rate; Taxoids | 2001 |
Standard chemotherapy for gastric carcinoma: is it a myth?
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Doxorubicin; Epirubicin; Fluorouracil; Humans; Methotrexate; Stomach Neoplasms; Survival Rate; United Kingdom | 2001 |
[Randomized trial on the effect of radiotherapy in addition to 6 cycles CMF in node-positive breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Treatment Outcome | 2001 |
[Long-term results of a randomized trial comparing breast-conserving therapy with mastectomy: European Organization for Research and Treatment of Cancer 10801 trial].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Node Excision; Mastectomy, Modified Radical; Mastectomy, Segmental; Methotrexate; Middle Aged; Multicenter Studies as Topic; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Treatment Outcome | 2001 |
1H NMR visible lipids are induced by phosphonium salts and 5-fluorouracil in human breast cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Drug Synergism; Female; Fluorouracil; Humans; Infant, Newborn; Lipid Metabolism; Magnetic Resonance Spectroscopy; Methotrexate; Mitochondria; Organophosphorus Compounds; Tumor Cells, Cultured | 2001 |
Analysis of the prognostic effects of inclusion in a clinical trial and of myelosuppression on survival after adjuvant chemotherapy for breast carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Prognosis; Retrospective Studies; Treatment Outcome | 2001 |
Dual role of vitamin C on lipid profile and combined application of cyclophosphamide, methotrexate and 5-fluorouracil treatment in fibrosarcoma-bearing rats.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Breast Neoplasms; Cholesterol; Cyclophosphamide; Female; Fibrosarcoma; Fluorouracil; Lipid Metabolism; Lipids; Methotrexate; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Wistar | 2001 |
Management of inoperable carcinoma of the breast by curative radiotherapy and chemo-hormonotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Radiography; Radiotherapy, Adjuvant; Survival Rate | 2001 |
Can expression of apoptosis genes, bcl-2 and bax, predict survival and responsiveness to chemotherapy in node-negative breast cancer patients?
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Biomarkers, Tumor; Breast Neoplasms; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Humans; Immunohistochemistry; Life Tables; Lymph Nodes; Methotrexate; Middle Aged; Predictive Value of Tests; Prognosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Estrogen; Receptors, Progesterone | 2001 |
Influence of adjuvant chemotherapy with cyclophosphamide, methotrexate and 5-fluorouracil on plasma melatonin and chosen hormones in breast cancer premenopausal patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Melatonin; Methotrexate; Middle Aged; Premenopause | 2001 |
Breast cancer survival and in vitro tumor response in the extreme drug resistance assay.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biological Assay; Breast Neoplasms; Cohort Studies; Cyclophosphamide; Disease Progression; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Predictive Value of Tests; Survival Analysis | 2001 |
Separation of selected anticancer drugs using superheated water as the mobile phase.
Topics: Antineoplastic Agents; Etoposide; Fluorouracil; Hot Temperature; Methotrexate; Water | 2001 |
Pharmacokinetics and toxicity of intravitreal chemotherapy for primary intraocular lymphoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Chromatography, High Pressure Liquid; Dexamethasone; Electroretinography; Eye Neoplasms; Female; Fluorouracil; Half-Life; Lymphoma; Male; Methotrexate; Rabbits; Retina; Vitreous Body | 2001 |
[A case of advanced gastric cancer with multiple liver metastases partially responding to combination intra-arterial chemotherapy via the hepatic artery and abdominal aorta].
Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta, Abdominal; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Methotrexate; Middle Aged; Stomach Neoplasms | 2001 |
[A case of locally advanced breast cancer treated with hyperthermia in combination with radiotherapy].
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Hyperthermia, Induced; Methotrexate; Middle Aged; Tamoxifen | 2001 |
[A case of recurring breast cancer causing pericardial metastasis showing a good response following local treatment with methotrexate].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiac Tamponade; Cyclophosphamide; Drainage; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Heart Neoplasms; Humans; Methotrexate; Middle Aged; Pericardial Effusion | 2001 |
[Clinical experience of intra-arterial chemotherapy for liver metastases of breast cancer patients].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Catheters, Indwelling; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Methotrexate; Middle Aged; Mitomycin; Retrospective Studies | 2001 |
[Pharmacokinetics of "subselective" arterial infusion chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta; Catheters, Indwelling; Drug Administration Schedule; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 2001 |
Combination chemotherapy of the taxanes and antimetabolites: its use and limitations.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Deoxycytidine; Drug Synergism; Fluorouracil; Gemcitabine; Humans; Methotrexate; Paclitaxel | 2001 |
Delivering adjuvant chemotherapy to women with early-stage breast carcinoma: current patterns of care.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Comorbidity; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymph Nodes; Methotrexate; Middle Aged | 2001 |
Management of a 16-year-old boy with adenocarcinoma at the esophageal gastric junction.
Topics: Adenocarcinoma; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Diagnosis, Differential; Doxorubicin; Esophagogastric Junction; Etoposide; Fluorouracil; Humans; Male; Methotrexate; Paclitaxel; Stomach Neoplasms | 2001 |
HER-2/neu overexpression and in vitro chemosensitivity to CMF and FEC in primary breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Epirubicin; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Methotrexate; Middle Aged; Receptor, ErbB-2; Up-Regulation | 2001 |
[Effect of beta-carotene on mouse transplantable mammary cancer MA737].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; beta Carotene; Cisplatin; Female; Fluorouracil; Mammary Neoplasms, Experimental; Methotrexate; Mice; Neoplasm Transplantation | 1999 |
Technical factors associated with radiation pneumonitis after local +/- regional radiation therapy for breast cancer.
Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Female; Fluorouracil; Follow-Up Studies; Humans; Incidence; Lymphatic Irradiation; Methotrexate; Radiation Pneumonitis; Radiography; Regression Analysis | 2002 |
[Clinical study on the expression level of lymphocyte function-related antigen of breast cancer patients].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drugs, Chinese Herbal; Female; Fluorouracil; Humans; Intercellular Adhesion Molecule-1; Lymphocyte Function-Associated Antigen-1; Lymphocytes; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness | 2000 |
Chemoradiation for metastatic SCCA: role of comorbidity.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Comorbidity; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Lymph Node Excision; Lymphatic Metastasis; Methotrexate; Radiotherapy, Adjuvant; Radiotherapy, High-Energy; Retrospective Studies; Severity of Illness Index; Survival Analysis | 2001 |
Prognostic value of thymidine phosphorylase expression in breast carcinoma.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Carcinoma, Ductal, Breast; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Fluorouracil; Follow-Up Studies; Humans; Life Tables; Methotrexate; Neoplasm Invasiveness; Neoplasm Proteins; Neovascularization, Pathologic; Predictive Value of Tests; Prognosis; Selective Estrogen Receptor Modulators; Survival Analysis; Tamoxifen; Thymidine Phosphorylase | 2002 |
P16INK4a protein expression is associated with poor survival of the breast cancer patients after CMF chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Differentiation; Cyclin-Dependent Kinase Inhibitor p16; Cyclophosphamide; Disease-Free Survival; Female; Flow Cytometry; Fluorouracil; Humans; Immunoenzyme Techniques; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Staging; Receptors, Estrogen; Receptors, Progesterone; Survival Rate; Tumor Suppressor Protein p53 | 2001 |
[A patient with advanced gastric cancer surviving for more than 5 years after neoadjuvant chemotherapy and curative resection].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Duodenal Neoplasms; Female; Fluorouracil; Gastrectomy; Humans; Lymph Node Excision; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Stomach Neoplasms | 2002 |
Acute abdomen during adjuvant chemotherapy: superior mesenteric artery thrombosis associated with CMF chemotherapy.
Topics: Abdomen, Acute; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Mesenteric Artery, Superior; Mesenteric Vascular Occlusion; Methotrexate; Middle Aged; Thrombosis | 2001 |
[Flow cytometry for testing chemosensitivity of malignant bone tumors].
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Neoplasms; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorouracil; Humans; Methotrexate; Mitomycin; Osteosarcoma | 1999 |
Clinical experience of capecitabine in metastatic breast cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Clinical Trials, Phase II as Topic; Cyclophosphamide; Deoxycytidine; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Multicenter Studies as Topic; Neoplasm Metastasis; Paclitaxel; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Failure | 2002 |
Sequential methotrexate and 5-fluorouracil therapy for gastric cancer patients with peritoneal dissemination: a retrospective study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Feasibility Studies; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Peritoneal Neoplasms; Retrospective Studies; Safety; Stomach Neoplasms; Survival Rate; Treatment Outcome | 2001 |
Lymphoblasts already in the DNA synthesis phase of the cell cycle can be reversibly arrested at the R/G transition.
Topics: Bromodeoxyuridine; Cell Cycle; Cell Line, Transformed; Chromosome Banding; Chromosomes, Human; DNA; DNA Replication; Flow Cytometry; Fluorouracil; Humans; Karyotyping; Kinetics; Lymphocyte Activation; Lymphocytes; Methotrexate; Mimosine; S Phase; Thymidine | 2001 |
Progesterone receptor status of breast cancer metastases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Metastasis; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Time Factors | 2002 |
Weight gain during adjuvant and neoadjuvant chemotherapy for breast cancer: an audit of 100 women receiving FEC or CMF chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Weight Gain | 2002 |
[Chemotherapy-associated myelosuppression in gynecological oncology].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cobalt Radioisotopes; Combined Modality Therapy; Cyclophosphamide; Data Interpretation, Statistical; Etoposide; Female; Fluorouracil; Hematopoiesis; Humans; Leukopoiesis; Lymph Node Excision; Lymphatic Metastasis; Mastectomy, Segmental; Methotrexate; Middle Aged; Ovarian Neoplasms; Platelet Count; Radioisotope Teletherapy; Radiotherapy Dosage | 2001 |
Equivalence between ovarian suppression and chemotherapy in the adjuvant treatment of endocrine-responsive breast cancer.
Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Estrogen Receptor Modulators; Female; Fluorouracil; Humans; Meta-Analysis as Topic; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Premenopause; Randomized Controlled Trials as Topic; Tamoxifen; Treatment Outcome | 2002 |
Meeting highlights: International consensus panel on the treatment of primary breast cancer.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Consensus Development Conferences as Topic; Disease-Free Survival; Estrogen Receptor Modulators; Female; Fluorouracil; Gonadotropin-Releasing Hormone; Humans; Methotrexate; Middle Aged; Ovariectomy; Premenopause; Survival Analysis; Tamoxifen; Treatment Outcome | 2002 |
Invasive ductal carcinoma associated with tubular adenoma of the breast.
Topics: Adenoma; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Node Excision; Mammography; Mastectomy; Methotrexate; Middle Aged; Neoplasms, Multiple Primary; Radiotherapy; Treatment Outcome; Ultrasonography | 2002 |
[Prognostic factors in lymph node negative breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Methotrexate; Multicenter Studies as Topic; Multivariate Analysis; Plasminogen Activator Inhibitor 1; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Sensitivity and Specificity; Serine Proteinase Inhibitors; Time Factors; Urokinase-Type Plasminogen Activator | 2002 |
[Comparison of epirubicin and cyclophosphamide in 2-dose levels and classical CMF protocol in node-positive breast cancer. An adjuvant Phase III trial].
Topics: Administration, Oral; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Clinical Trials, Phase III as Topic; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Meta-Analysis as Topic; Methotrexate; Randomized Controlled Trials as Topic; Tamoxifen; Time Factors | 2002 |
[A case of gastric cancer with paraaortic lymph node metastasis responding to preoperative chemotherapy and surviving 4 years and 4 months after total gastrectomy].
Topics: Adenocarcinoma, Scirrhous; Aged; Antineoplastic Combined Chemotherapy Protocols; Aorta; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Gastrectomy; Humans; Leucovorin; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Stomach Neoplasms; Survivors; Tegafur; Uracil | 2002 |
[A case of complete response (CR) persisting for 2 years and 10 months from UFT-E in a patient with liver metastasis of gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Fluorouracil; Gastrectomy; Humans; Leucovorin; Liver Neoplasms; Lymph Node Excision; Male; Methotrexate; Middle Aged; Remission Induction; Stomach Neoplasms; Tegafur; Uracil | 2002 |
Population pharmacokinetics of adjuvant cyclophosphamide, methotrexate and 5-fluorouracil (CMF).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Chromatography, High Pressure Liquid; Cyclophosphamide; Female; Fluorouracil; Humans; Infusions, Intravenous; Methotrexate; Middle Aged | 2002 |
Dihydropyrimidine dehydrogenase enzyme deficiency: clinical and genetic assessment of prevalence in Turkish cancer patients.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dihydrouracil Dehydrogenase (NADP); DNA Mutational Analysis; Female; Fluorouracil; Genetics, Population; Humans; Male; Methotrexate; Neoplasms; Oxidoreductases; Prevalence; Turkey | 2002 |
[Incidence of emesis in outpatients on chemotherapy for breast cancer and the clinical efficacy of ondansetron hydrochloride tablets].
Topics: Ambulatory Care; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Nausea; Ondansetron; Vomiting, Anticipatory | 2002 |
[Complicated antiphospholid antibody syndrome].
Topics: Antineoplastic Combined Chemotherapy Protocols; Antiphospholipid Syndrome; Breast Neoplasms; Carcinoma, Ductal, Breast; Cerebral Infarction; Combined Modality Therapy; Cyclophosphamide; Diagnosis, Differential; Diagnostic Imaging; Female; Fluorouracil; Humans; Mastectomy, Segmental; Methotrexate; Middle Aged; Patient Care Team; Postoperative Complications; Pulmonary Embolism; Thrombophlebitis | 2002 |
Study of chromosome damage in patients with breast cancer treated by two antineoplastic treatments.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Cell Division; Chromosome Aberrations; Chromosomes, Human; Cyclophosphamide; DNA Damage; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitotic Index; Sister Chromatid Exchange | 2002 |
Quantitative assessment of the clavicle radiostructure as a tool for estimation of the osteopathic effect of breast cancer chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Diseases; Breast Neoplasms; Clavicle; Cyclophosphamide; Female; Fluorouracil; Humans; Image Processing, Computer-Assisted; Methotrexate; Middle Aged; Osteoporosis; Premenopause; Radiography; Reproducibility of Results; Sensitivity and Specificity; Software | 2002 |
Local recurrence in the breast after conservative surgery--a study of prognosis and prognostic factors in 391 women.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Postoperative Care; Prognosis; Survival Analysis | 2002 |
Neoadjuvant chemotherapy followed by salvage surgery: effect on survival of patients with primary noncurative gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mitomycin; Neoplasm Staging; Preoperative Care; Prognosis; Salvage Therapy; Stomach Neoplasms; Survival Analysis | 2002 |
Concurrent cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy and radiotherapy for breast carcinoma: a well tolerated adjuvant regimen.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Survival Rate | 2002 |
[Breast carcinoma in accessory gland: a case report].
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Node Excision; Lymphatic Metastasis; Methotrexate; Middle Aged; Tamoxifen; Time Factors | 2002 |
Therapy-induced leukemias and myelodysplastic syndromes after breast cancer treatment: an underemphasized clinical problem.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Carcinoma, Ductal, Breast; Cyclophosphamide; Fatal Outcome; Female; Fluorouracil; Humans; Leukemia, Myeloid, Acute; Leukemia, Radiation-Induced; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Tamoxifen | 2002 |
Early changes in [18F]FLT uptake after chemotherapy: an experimental study.
Topics: Antineoplastic Agents; Artifacts; Carcinoma, Squamous Cell; Cell Survival; Cisplatin; Deoxycytidine; Dideoxynucleosides; Dose-Response Relationship, Drug; Esophageal Neoplasms; Fluorodeoxyglucose F18; Fluorouracil; Gemcitabine; Humans; Methotrexate; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Statistics as Topic; Tumor Cells, Cultured | 2002 |
A case of advanced esophageal cancer with extensive lymph node metastases successfully treated with multimodal therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Esophageal Neoplasms; Fluorouracil; Humans; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Survivors | 2002 |
Thymidylate synthase protein expression in colorectal cancer metastases predicts for clinical outcome to leucovorin-modulated bolus or infusional 5-fluorouracil but not methotrexate-modulated bolus 5-fluorouracil.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy, Needle; Chi-Square Distribution; Cohort Studies; Colorectal Neoplasms; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Immunohistochemistry; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Predictive Value of Tests; Probability; Prognosis; Sensitivity and Specificity; Survival Rate; Thymidylate Synthase; Treatment Outcome | 2002 |
Chemosensitization of carmustine with maitake beta-glucan on androgen-independent prostatic cancer cells: involvement of glyoxalase I.
Topics: Agaricales; Androgens; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; beta-Glucans; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Fluorouracil; Glucans; Humans; In Vitro Techniques; Lactoylglutathione Lyase; Male; Methotrexate; Prostatic Neoplasms; Tumor Cells, Cultured | 2002 |
[A case of pyloric or antral malignant stenosis treated with arterial infusion chemotherapy and palliative therapy--self-expandable metal stents through gastrostomy].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Methotrexate; Middle Aged; Pyloric Antrum; Pyloric Stenosis; Quality of Life; Stents; Stomach Neoplasms | 2002 |
[A case of gastric cancer associated with synchronous liver metastasis successfully treated with combination therapy of systemic and hepatic arterial infusion chemotherapy].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 2002 |
Adjuvant therapy for premenopausal women with breast cancer: is it time for another paradigm shift?
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Premenopause | 2002 |
Goserelin versus cyclophosphamide, methotrexate, and fluorouracil as adjuvant therapy in premenopausal patients with node-positive breast cancer: The Zoladex Early Breast Cancer Research Association Study.
Topics: Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Goserelin; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Premenopause; Receptors, Estrogen | 2002 |
Delays in diagnosing breast cancer--the impact of concurrent pregnancy and lactation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Lactation; Mastectomy; Methotrexate; Pregnancy; Pregnancy Complications, Neoplastic; Tamoxifen | 2002 |
Pasteurella multocida infection in a post-chemotherapy neutropenic host following cat exposure.
Topics: Aged; Animals; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cat Diseases; Cats; Ciprofloxacin; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neutropenia; Pasteurella Infections; Pasteurella multocida | 2002 |
Expression of cell cycle regulatory proteins in breast carcinomas before and after preoperative chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Cycle Proteins; Chemotherapy, Adjuvant; Cyclin D3; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cyclophosphamide; Docetaxel; Enzyme Inhibitors; Epirubicin; Female; Fluorouracil; Gene Expression; Genes, p53; Genes, Tumor Suppressor; Humans; Ki-67 Antigen; Methotrexate; Middle Aged; Paclitaxel; Preoperative Care; Receptors, Steroid; Taxoids; Transcription Factors; Treatment Outcome; Tumor Suppressor Proteins | 2003 |
Optimal chemotherapy for women with breast cancer: the plot thickens.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Confidence Intervals; Cyclophosphamide; Data Interpretation, Statistical; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Paclitaxel; Receptors, Estrogen; Research Design; Taxoids; Treatment Outcome | 2003 |
Concurrent sequencing of full-dose CMF chemotherapy and radiation therapy in early breast cancer has no effect on treatment delivery.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Delivery Systems; Female; Fluorouracil; Follow-Up Studies; Hematologic Diseases; Humans; Methotrexate; Middle Aged; Patient Satisfaction; Radiation Dosage | 2003 |
Sclerosing encapsulating peritonitis (SEP) as a delayed complication of continuous hyperthermic peritoneal perfusion (CHPP): report of a case.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Female; Fluorouracil; Humans; Hyperthermia, Induced; Intestinal Obstruction; Methotrexate; Middle Aged; Mitomycin; Peritonitis; Sclerosis; Stomach Neoplasms; Time Factors | 2003 |
Retroviral transduction of a mutant dihydrofolate reductase-thymidylate synthase fusion gene into murine marrow cells confers resistance to both methotrexate and 5-fluorouracil.
Topics: 3T3 Cells; Animals; Blotting, Western; Bone Marrow Cells; Cell Survival; Cells, Cultured; Drug Resistance; Fluorouracil; Gene Expression; Genetic Vectors; Male; Methotrexate; Mice; Mice, Inbred C57BL; Mutation; Protein Biosynthesis; Recombinant Fusion Proteins; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Transduction, Genetic | 2003 |
Second malignancies following adjuvant chemotherapy: 6-year results from a Belgian randomized study comparing cyclophosphamide, methotrexate and 5-fluorouracil (CMF) with an anthracycline-based regimen in adjuvant treatment of node-positive breast cancer
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Belgium; Breast Neoplasms; Chemotherapy, Adjuvant; Confidence Intervals; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Leukemia, Myeloid; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasms, Second Primary; Randomized Controlled Trials as Topic; Retrospective Studies | 2003 |
Large diversity in transport-mediated methotrexate resistance in human leukemia cell line CCRF-CEM established in a high concentration of leucovorin.
Topics: Amino Acid Substitution; Antimetabolites, Antineoplastic; Biological Transport; Carrier Proteins; Codon; DNA Mutational Analysis; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Humans; Inhibitory Concentration 50; Intracellular Fluid; Leucovorin; Leukemia, T-Cell; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Mutation, Missense; Neoplasm Proteins; Point Mutation; Selection, Genetic; Sequence Deletion; Tetrahydrofolate Dehydrogenase; Trimetrexate; Tumor Cells, Cultured | 2003 |
Different responses to preoperative chemotherapy for invasive lobular and invasive ductal breast carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Prospective Studies; Survival Analysis; Treatment Outcome | 2003 |
Adjuvant chemotherapy in breast cancer: back to the future.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Staging; Randomized Controlled Trials as Topic; Vincristine | 2003 |
S-1 in the treatment of advanced and recurrent gastric cancer: current state and future prospects.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Forecasting; Humans; Japan; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Pyridines; Severity of Illness Index; Stomach Neoplasms; Survival Analysis; Tegafur; Time Factors; Treatment Outcome | 2003 |
Simultaneous occurrence of hepatic focal nodular hyperplasia and uterine endometrial stromal nodule in a patient having treated breast infiltrating ductal carcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Comorbidity; Cyclophosphamide; Endometrial Stromal Tumors; Female; Fluorouracil; Focal Nodular Hyperplasia; Humans; Leiomyoma; Magnetic Resonance Imaging; Methotrexate; Neoplasms, Multiple Primary; Uterine Neoplasms | 2003 |
[Male breast cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms, Male; Combined Modality Therapy; Cyclophosphamide; Diagnosis, Differential; Fluorouracil; Gynecomastia; Humans; Male; Mammography; Methotrexate; Prognosis; Ultrasonography, Mammary | 2003 |
[Combined MTX.5-FU.CDGP for the treatment of head and neck cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Organoplatinum Compounds; Radiography; Radiotherapy, Adjuvant; Remission Induction; Survival Analysis | 2003 |
Can endocrine treatment for hormone-positive premenopausal women with early breast cancer replace adjuvant chemotherapy?
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Goserelin; Humans; Methotrexate; Premenopause; Randomized Controlled Trials as Topic; Tamoxifen | 2003 |
Paradigm shift in adjuvant treatment of receptor positive premenopausal breast cancer patients? Not yet!
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Goserelin; Humans; Infant; Methotrexate; Neoplasm Recurrence, Local; Ovariectomy; Premenopause; Survival Rate; Tamoxifen | 2003 |
Combined endocrine blockade in premenopausal breast cancer: a superior therapeutic option for adjuvant management?
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Goserelin; Humans; Methotrexate; Neoplasm Recurrence, Local; Ovariectomy; Premenopause; Survival Rate; Tamoxifen | 2003 |
Colloidal anticancer drugs bioavailabilities in oral administration models.
Topics: Animals; Antineoplastic Agents; Biological Availability; Biological Transport; Caco-2 Cells; Colloids; Colon; Colonic Neoplasms; Drug Stability; Female; Fluorouracil; Humans; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; L-Lactate Dehydrogenase; Liposomes; Male; Methotrexate; Nanotechnology; Rats; Rats, Wistar; Tissue Distribution; Vincristine | 2003 |
Rare expression of epithelial cell adhesion molecule on residual micrometastatic breast cancer cells after adjuvant chemotherapy.
Topics: Adult; Aged; Anthracyclines; Antigens, Neoplasm; Bone Marrow Cells; Breast Neoplasms; Cell Adhesion; Cell Adhesion Molecules; Cell Line, Tumor; Centrifugation, Density Gradient; Chemotherapy, Adjuvant; Cohort Studies; Cyclophosphamide; Epithelial Cell Adhesion Molecule; Epitopes; Female; Fluorouracil; Humans; Immunohistochemistry; Immunotherapy; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms; Prognosis | 2003 |
Prognostic implication of cyclin E expression and its relationship with cyclin D1 and p27Kip1 expression on tissue microarrays of node negative breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Cycle Proteins; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase Inhibitor p27; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Nodes; Methotrexate; Oligonucleotide Array Sequence Analysis; Prognosis; Survival Analysis; Tumor Suppressor Proteins | 2003 |
Chemotherapy and antiangiogenesis--drug-specific, dose-related effects.
Topics: Animals; Antineoplastic Agents; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Endothelial Growth Factors; Etoposide; Fluorouracil; Humans; Injections, Intravenous; Intercellular Signaling Peptides and Proteins; Lymphokines; Male; Mesentery; Methotrexate; Neovascularization, Physiologic; Paclitaxel; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Weight Gain | 2003 |
Risk of acute leukemia following epirubicin-based adjuvant chemotherapy: a report from the National Cancer Institute of Canada Clinical Trials Group.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Cytarabine; Epirubicin; Female; Fluorouracil; Humans; Leukemia; Methotrexate; Middle Aged; Neoplasms, Multiple Primary; Risk | 2003 |
Effect of different neoadjuvant chemotherapy regimens on locally advanced breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Survival Rate | 2003 |
[A case of advanced gastric cancer with liver and intra-abdominal lymph node metastasis treated by hypertensive selective chemotherapy with pharmacokinetic modulating chemotherapy].
Topics: Adenocarcinoma; Aged; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Pancreatic Neoplasms; Stomach Neoplasms; Tegafur | 2003 |
ErbB2 overexpression in human breast carcinoma is correlated with p21Cip1 up-regulation and tyrosine-15 hyperphosphorylation of p34Cdc2: poor responsiveness to chemotherapy with cyclophoshamide methotrexate, and 5-fluorouracil is associated with Erb2 over
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; CDC2 Protein Kinase; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cyclophosphamide; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Immunohistochemistry; Methotrexate; Middle Aged; Phosphorylation; Receptor, ErbB-2; RNA, Messenger; Tyrosine; Up-Regulation | 2003 |
Remission of methotrexate-resistant rheumatoid arthritis after receiving 5-fluorouracil for colon cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Antirheumatic Agents; Arthritis, Rheumatoid; Colonic Neoplasms; Drug Resistance; Fluorouracil; Humans; Male; Methotrexate; Remission Induction | 2003 |
A comparative study of 5-fluorouracil (FU), 5-fluorodeoxyuridine (FUDR), and methotrexate (MTX)-progress report.
Topics: Antineoplastic Agents; Floxuridine; Fluorouracil; Folic Acid Antagonists; Methotrexate; Nucleosides; Nucleotides; Research Report; Uracil | 1962 |
Effect of antimetabolites on epidermal structures.
Topics: Antimetabolites; Epidermis; Fluorouracil; Hair; Humans; Mercaptopurine; Methotrexate; Psoriasis; Skin | 1963 |
Cancer chemotherapy by arterial infusion.
Topics: Antineoplastic Agents; Fluorouracil; Humans; Injections; Injections, Intramuscular; Leucovorin; Methotrexate; Neoplasms | 1963 |
Chemotherapy of malignant disease. I. Solid tumours.
Topics: Cyclophosphamide; Dactinomycin; Fluorouracil; Mechlorethamine; Methotrexate; Mitomycin; Mitomycins; Neoplasms; Thiotepa | 1962 |
Characterization of resistance to amethopterin, 8-azaguanine and several fluorinated pyrimidines in the murine lymphocytic neoplasm, P388.
Topics: Animals; Antineoplastic Agents; Azaguanine; Fluorouracil; Leukemia; Leukemia, Lymphoid; Lymphoma; Methotrexate; Mice; Nucleotides; Pyrimidines | 1962 |
Cancer chemotherapy by intra-arterial infusion.
Topics: Dactinomycin; Fluorouracil; Humans; Infusions, Intra-Arterial; Mechlorethamine; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Thiotepa | 1963 |
The influence of certain antimetabolites on the incorporation of orotic acid into pseudouridine in animals.
Topics: Animals; Antimetabolites; Fluorouracil; Methotrexate; Nucleosides; Orotic Acid; Pseudouridine; Uracil Nucleotides | 1963 |
ASSOCIATION OF INCREASED DIHYDROFOLATE REDUCTASE LEVELS AND CHROMOSOME ALTERATION IN AMETHOPTERIN-RESISTANT SUBLINES OF LEUKEMIA L1210.
Topics: Animals; Azaserine; Chromosomes; Fluorouracil; Folic Acid; Genetics; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Oxidoreductases; Research; Tetrahydrofolate Dehydrogenase | 1963 |
SELECTION OF CHROMOSOMAL VARIANT IN AMETHOPTERIN-RESISTANT SUBLINES OF LEUKEMIA L1210 WITH INCREASED LEVELS OF DIHYDROFOLATE REDUCTASE.
Topics: Animals; Chromosomes; Fluorouracil; Genetics; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Oxidoreductases; Research; Tetrahydrofolate Dehydrogenase | 1963 |
CONTINUOUS INFUSION OF ADVANCED PELVIC MALIGNANCIES BY RETROGRADE FEMORAL CATHETER.
Topics: Catheters; Fluorouracil; Infusions, Parenteral; Leucovorin; Methotrexate; Neoplasms; Pelvic Neoplasms; Pelvis | 1963 |
CHEMOTHERAPY OF METASTATIC LIVER CANCER BY PROLONGED HEPATIC-ARTERY INFUSION.
Topics: Alkaline Phosphatase; Bile Duct Neoplasms; Bilirubin; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Erythrocyte Count; Female; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Liver Neoplasms; Methotrexate; Neoplasm Metastasis; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms; Sulfobromophthalein; Transaminases; Uterine Cervical Neoplasms | 1964 |
[REPORT ON REGIONAL CHEMOTHERAPY IN CANCEROLOGY].
Topics: Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Mannomustine; Methotrexate; Neoplasms; Toxicology | 1963 |
[PROLONGED INTRA-ARTERIAL CHEMOTHERAPY USING AN ANTINEOPLASTIC INFUSION IN THE TREATMENT OF INOPERABLE NEOPLASIA. 1. INTRODUCTION, MATERIAL AND METHOD].
Topics: Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Infusions, Parenteral; Mechlorethamine; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Toxicology | 1963 |
HEPATIC CHEMOTHERAPY BY ARTERIAL AND VENOUS INFUSION.
Topics: Catheterization; Clinical Enzyme Tests; Dogs; Fluorouracil; Hepatic Artery; Hepatic Veins; Infusions, Parenteral; Leucovorin; Liver Function Tests; Liver Neoplasms; Methotrexate; Research; Toxicology; Veins | 1964 |
IN VITRO TEST SYSTEMS FOR CANCER CHEMOTHERAPY. II. CORRELATION OF IN VITRO INHIBITION OF DEHYDROGENASE AND GROWTH WITH IN VIVO INHIBITION OF EHRLICH ASCITES TUMOR.
Topics: Animals; Antineoplastic Agents; Arsenicals; Carbamates; Carcinoma; Carcinoma, Ehrlich Tumor; Colchicine; Dactinomycin; Diethylstilbestrol; Enzyme Inhibitors; Fluorouracil; Hydrocortisone; In Vitro Techniques; Mechlorethamine; Mercaptopurine; Methotrexate; Mice; Oxidoreductases; Research; Thalidomide; Thiotepa | 1963 |
DRUGS OF CURRENT USE FOR THE TREATMENT OF CANCER AND ALLIED DISEASES.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Aziridines; Busulfan; Colchicine; Dactinomycin; Diethylstilbestrol; Estrogens; Fluorouracil; Gonadal Steroid Hormones; Mercaptopurine; Methotrexate; Mitomycin; Mitomycins; Neoplasms; Podophyllum; Progestins; Quinones; Thiotepa; Triethylenemelamine; Urethane; Vinblastine | 1963 |
CANCER CHEMOTHERAPY BY PROLONGED ARTERIAL INFUSION.
Topics: Angiography; Arm; Brachiocephalic Trunk; Brain Neoplasms; Carotid Arteries; Chemotherapy, Cancer, Regional Perfusion; Floxuridine; Fluorescent Dyes; Fluorouracil; Head and Neck Neoplasms; Hepatic Artery; Humans; Iliac Artery; Leg; Liver Neoplasms; Methotrexate; Neoplasms; Pelvic Neoplasms; Subclavian Artery; Temporal Arteries; Thoracic Neoplasms; Toxicology | 1964 |
INTRA-ARTERIAL INFUSION FOR HEAD AND NECK CANCER.
Topics: Antineoplastic Agents; Brain Neoplasms; Dactinomycin; Facial Neoplasms; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrogen Peroxide; Infusions, Intra-Arterial; Infusions, Parenteral; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms; Neoplasms; Nitrogen Mustard Compounds | 1964 |
DOSE-RESPONSE RELATIONSHIPS FOR AGENTS INHIBITING THE IMMUNE RESPONSE.
Topics: Allergy and Immunology; Antibody Formation; Antineoplastic Agents; Autoimmune Diseases; Cyclophosphamide; Fluorouracil; Immunity; Mannomustine; Mercaptopurine; Methotrexate; Mice; Mortality; Research; Thioguanine; Toxicology; Transplantation; Triethylenemelamine; Typhoid-Paratyphoid Vaccines; Vinblastine | 1964 |
CHEMOTHERAPY FOR CANCER.
Topics: Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Dactinomycin; Exudates and Transudates; Fluorouracil; Humans; Mercaptopurine; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Pericardium; Peritoneal Cavity; Pleural Effusion; Surgical Procedures, Operative; Vinblastine | 1964 |
CLINICOPATHOLOGIC CONFERENCE.
Topics: Black People; Bromides; Diagnosis, Differential; Drug Eruptions; Fluorouracil; Granuloma; Humans; Keratoacanthoma; Methotrexate; Neoplasm Metastasis; Neoplasms; Pathology | 1964 |
[INTRAARTERIAL INFUSIONS AND REGIONAL PERFUSION OF ANTIMITOTICS].
Topics: Antimitotic Agents; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Humans; Infusions, Intra-Arterial; Injections; Injections, Intra-Arterial; Melphalan; Methotrexate; Thiotepa | 1964 |
CURRENT STATUS OF CHEMOTHERAPY OF CANCER.
Topics: Alkylating Agents; Anti-Bacterial Agents; Antineoplastic Agents; Black People; Chemotherapy, Cancer, Regional Perfusion; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Dermatologic Agents; DNA; DNA, Neoplasm; Fluorouracil; Geriatrics; Humans; Mechlorethamine; Melphalan; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Pharmacology; Thiotepa; Toxicology; Triethylenemelamine; Vinblastine; Vincristine | 1964 |
EFFECTS OF IONIZING IRRADIATION AND CHEMOTHERAPEUTIC AGENTS ON HUMAN CHROMOSOMES.
Topics: Antineoplastic Agents; Biomedical Research; Chlorambucil; Choriocarcinoma; Chromosome Aberrations; Chromosomes, Human; Endometriosis; Female; Fluorouracil; Geriatrics; Humans; Leukocytes; Melanoma; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Ovarian Neoplasms; Sarcoma; Thiotepa; Uterine Cervical Neoplasms; Uterine Neoplasms; Vinblastine | 1964 |
THE EFFECT OF A PHTHALANILIDE DERIVATIVE ON LIPIDE METABOLISM IN L1210 LEUKEMIA CELLS.
Topics: Anilides; Animals; Antineoplastic Agents; Carbon Isotopes; Cholesterol; Cyclophosphamide; Fatty Acids; Fluorouracil; Leukemia L1210; Lipid Metabolism; Mercaptopurine; Methotrexate; Mice; Nitroso Compounds; Pharmacology; Phthalic Acids; Research | 1964 |
STUDIES ON HUMAN MELANOMA CELLS IN TISSUE CULTURE. II. EFFECTS OF SEVERAL CANCER CHEMOTHERAPEUTIC AGENTS ON CYTOLOGY AND GROWTH.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Chlorambucil; Dactinomycin; Fluorouracil; Melanoma; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Pharmacology; Thiotepa; Tissue Culture Techniques | 1964 |
THE CLINICAL EFFECTS OF THE CONTINUOUS INTRAVENOUS INFUSION OF CANCER CHEMOTHERAPEUTIC COMPOUNDS.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antineoplastic Agents; Floxuridine; Fluorouracil; Infusions, Intravenous; Infusions, Parenteral; Methotrexate; Mitomycin; Mitomycins; Neoplasms; Thymidine | 1964 |
III. IMPROVEMENT OF CANCER CHEMOTHERAPY IN MAN.
Topics: Animals; Antineoplastic Agents; Chlorambucil; Fluorouracil; Leukemia; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Pharmacology; Pyrimidines; Research; Stilbamidines; Triparanol | 1964 |
INDIVIDUALIZED CHEMOTHERAPY BY IN VITRO DRUG SELECTION.
Topics: Antineoplastic Agents; Bone Neoplasms; Dactinomycin; Female; Floxuridine; Fluorouracil; Genital Neoplasms, Female; Humans; In Vitro Techniques; Intestinal Neoplasms; Leukemia; Mechlorethamine; Melanoma; Mercaptopurine; Methotrexate; Neoplasms; Pharyngeal Neoplasms; Respiratory Tract Neoplasms; Stomach Neoplasms; Thiotepa | 1964 |
CARCINOMA OF THE COLON IN ULCERATIVE COLITIS.
Topics: Aged; Aging; Cell Biology; Colitis; Colitis, Ulcerative; Colonic Neoplasms; Fluorouracil; Humans; Mechlorethamine; Methotrexate; Neoplasms; Pathology; Polyps; Radiography; Surgical Procedures, Operative | 1964 |
PROTRACTED AMBULATORY INFUSION CANCER CHEMOTHERAPY BY THE WATKINS CHRONOMETRIC INFUSOR.
Topics: Adenoma; Antineoplastic Agents; Breast Neoplasms; Carcinosarcoma; Colonic Neoplasms; Dermatitis, Exfoliative; Equipment and Supplies; Floxuridine; Fluorouracil; Humans; Infusion Pumps; Infusions, Parenteral; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Melanoma; Methotrexate; Mitomycin; Mitomycins; Pancreatic Neoplasms; Stomach Neoplasms; Testicular Neoplasms; Thyroid Neoplasms; Tongue Neoplasms; Toxicology | 1964 |
COUPLING OF CYCLIC CHEMOTHERAPEUTIC COMPOUNDS TO IMMUNE GAMMA-GLOBULINS.
Topics: Aniline Compounds; Anti-Bacterial Agents; Azo Compounds; Chemistry, Pharmaceutical; Chlorambucil; Dialysis; Fluorouracil; gamma-Globulins; Immune Sera; Immunoglobulins; Mercaptopurine; Methotrexate; Nitrogen Mustard Compounds; Renal Dialysis; Research; Tetracycline; Thiotepa; Ultraviolet Rays; Uracil Mustard | 1964 |
A COMPARISON OF THE EFFECTS OF SELECTED CYTOTOXIC AGENTS ON THE PRIMARY AGGLUTININ RESPONSE IN RATS INJECTED WITH SHEEP ERYTHROCYTES.
Topics: Agglutinins; Animals; Antibodies; Antibody Formation; Antigen-Antibody Reactions; Antigens; Antineoplastic Agents; Cyclophosphamide; Cytotoxins; Erythrocytes; Floxuridine; Fluorouracil; Immunity; Immunization; Mechlorethamine; Mercaptopurine; Methotrexate; Purines; Rats; Research; Sheep; Toxicology; Vinblastine | 1964 |
THE TREATMENT OF CANCER BY ISOLATION PERFUSION.
Topics: Alkylating Agents; Anti-Bacterial Agents; Antimetabolites; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Chlorambucil; Cyclophosphamide; Fluorouracil; Mechlorethamine; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Nursing; Thiotepa; Toxicology | 1964 |
[REGIONAL INTRA-ARTERIAL CYTOSTATIC THERAPY OF MALIGNANT TUMORS OF THE HEAD AND NECK].
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Neoplasms; Paranasal Sinus Neoplasms; Skin Neoplasms | 1964 |
EXPERIMENTAL CHEMOTHERAPY STUDIES. V. THE COLLATERAL SENSITIVITY TO ALKYLATING AGENTS OF SEVERAL ANTIMETABOLITE-RESISTANT ASCITES TUMORS IN MICE.
Topics: Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Ascites; Azaserine; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Fluorouracil; Leukemia L1210; Leukemia, Experimental; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; Pharmacology; Research; Thioguanine; Thiotepa; Toxicology | 1964 |
INFUSION CHEMOTHERAPY FOR ABDOMINAL MALIGNANCIES. METHODOLOGY AND PRELIMINARY REPORT.
Topics: Abdominal Neoplasms; Angiography; Antimetabolites; Antineoplastic Agents; Aorta; Aorta, Abdominal; Brachial Artery; Catheterization; Drug Therapy; Femoral Artery; Fluoroscopy; Fluorouracil; Hepatic Artery; Humans; Methotrexate; Palliative Care; Perfusion; Phenylalanine; Thiotepa | 1964 |
ANTIMETABOLITE THERAPY IN MIDLINE LETHAL GRANULOMA.
Topics: Antimetabolites; Autoimmune Diseases; DNA; Drug Therapy; Fluorouracil; Granuloma; Granuloma, Lethal Midline; Humans; Infusions, Parenteral; Injections; Injections, Intra-Arterial; Injections, Intravenous; Methotrexate; Pharmacology; RNA | 1964 |
OBSERVATIONS ON THE USE OF CANCER CHEMOTHERAPEUTIC AGENTS IN PATIENTS WITH MYCOSIS FUNGOIDES.
Topics: Alkylating Agents; Anti-Bacterial Agents; Antineoplastic Agents; Carbamates; Chlorambucil; Dactinomycin; Drug Therapy; Fluorouracil; Humans; Methotrexate; Mitomycin; Mitomycins; Mycosis Fungoides; Neoplasms; Palliative Care; Skin Neoplasms; Thiotepa; Tissue Culture Techniques; Vinblastine | 1964 |
REGRESSION OF METASTATIC HEPATOMEGALY FROM MAMMARY CARCINOMA. CYTOTOXIC COMBINATION CHEMOTHERAPY WITH 5-FU.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Hepatomegaly; Humans; Liver Neoplasms; Methotrexate; Neoplasm Metastasis; Neoplasms; Prednisone; Testosterone; Thiotepa; Toxicology; Vitamin B 12 | 1964 |
COMBINATION OF SURGERY AND CHEMOTHERAPY IN THE TREATMENT OF ORAL CANCER.
Topics: DNA; DNA, Neoplasm; Drug Therapy; Fluorouracil; Humans; Methotrexate; Mouth Neoplasms; Neck Dissection; Neoplasms; Surgical Procedures, Operative; Thymidine | 1964 |
CLOSED PELVIC PERFUSION: ISOLATION PERFUSION OF THE PELVIS WITHOUT CELIOTOMY.
Topics: Catheterization; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Drug Therapy; Fluorouracil; Humans; Leucovorin; Methotrexate; Neoplasms; Pelvic Neoplasms; Pelvis; Perfusion; Tourniquets | 1964 |
THE TREATMENT OF ADVANCED CANCER WITH A COMBINATION OF 5-FLUOROURACIL, CYTOXAN, AND METHOTREXATE.
Topics: Cyclophosphamide; Drug Therapy; Fluorouracil; Humans; Methotrexate; Neoplasms; Toxicology | 1964 |
PELVIC PERFUSION AND CARCINOMA OF THE RECTUM.
Topics: Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Equipment and Supplies; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Neoplasms; Nitrogen Mustard Compounds; Palliative Care; Pelvic Neoplasms; Pelvis; Rectal Neoplasms; Rectum; Tourniquets | 1965 |
COMBINED INTRA-ARTERIAL CHEMOTHERAPY AND RADIATION TREATMENT FOR ADVANCED CERVICAL CARCINOMA. THE MCCALL TECHNIQUE AND RESULTS.
Topics: Chemotherapy, Cancer, Regional Perfusion; Drug Therapy; Drug Therapy, Combination; Female; Fluorouracil; Geriatrics; Humans; Methotrexate; Neoplasms; Toxicology; Uterine Cervical Neoplasms | 1965 |
BLOOD AND URINE LEVELS OF ANTITUMOR AGENTS DETERMINED WITH CELL CULTURE METHODS.
Topics: Antineoplastic Agents; Biological Assay; Blood Chemical Analysis; Chromatography; Cyclophosphamide; Dactinomycin; Fluorouracil; Mechlorethamine; Mercaptopurine; Methotrexate; Nucleosides; Pharmacology; Streptovaricin; Tissue Culture Techniques; Toxicology; Urine; Vinblastine | 1965 |
REGIONAL ARTERIAL INFUSION OF ANTIMETABOLITES. AN ANALYSIS OF THE RESULTS OBTAINED IN 33 PATIENTS WITH MALIGNANT TUMORS OF THE HEAD AND NECK.
Topics: Antimetabolites; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Injections, Intra-Arterial; Lymphatic Metastasis; Lymphoma; Maxillary Neoplasms; Methotrexate; Mouth Neoplasms; Neoplasms; Nose Neoplasms; Parotid Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms | 1965 |
[ANTI-CANCER CHEMOTHERAPY BY PROLONGED INTRA-ARTERIAL INFUSIONS].
Topics: Adrenal Cortex Hormones; Aminocaproates; Aminocaproic Acid; Anti-Bacterial Agents; Chemotherapy, Cancer, Regional Perfusion; Coagulase; Drug Therapy; Fluorouracil; Folic Acid; Humans; Hydrolases; Infusions, Intra-Arterial; Methotrexate; Neoplasms; Thiotepa; Vitamin B Complex | 1965 |
TUMORS OF THE SKIN. IV. DOUBLE-BLIND STUDY ON EFFECTS OF LOCAL ADMINISTRATION OF ANTI-TUMOR AGENTS IN BASAL CELL CARCINOMA.
Topics: Antineoplastic Agents; Carcinoma, Basal Cell; Dactinomycin; Double-Blind Method; Drug Therapy; Fluorouracil; Humans; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Ointments; Skin Neoplasms; Spiramycin; Toxicology | 1965 |
IN VITRO TEST SYSTEMS FOR CANCER CHEMOTHERAPY. 3. PRELIMINARY STUDIES OF SPONTANEOUS MAMMARY TUMORS IN MICE.
Topics: Alkylating Agents; Animals; Carcinoma, Ehrlich Tumor; Dactinomycin; Fluorouracil; Hydrocortisone; In Vitro Techniques; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mechlorethamine; Mercaptopurine; Metabolism; Methotrexate; Mice; Oxidoreductases; Research; Thiotepa; Tissue Culture Techniques; Toxicology | 1965 |
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. I. SUSPENSION CELL CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA.
Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Floxuridine; Fluorouracil; Glycine; Liver Neoplasms; Liver Neoplasms, Experimental; Metabolism; Methotrexate; Mutation; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Pyrimidines; Rats; Research; Serine; Thymidine; Thymidine Kinase; Thymine; Tissue Culture Techniques; Toxicology; Uracil | 1965 |
CLOSED PELVIC PERFUSION: A NEW APPROACH TO THE PROBLEM OF ADVANCED GYNECOLOGIC MALIGNANCY.
Topics: Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Drug Therapy; Female; Fluorouracil; Genital Neoplasms, Female; Geriatrics; Humans; Methotrexate; Neoplasm Recurrence, Local; Neoplasms; Palliative Care; Pelvis; Prognosis; Uracil Mustard; Uterine Cervical Neoplasms; Vulvar Neoplasms | 1965 |
Raynaud's phenomenon after combined adjuvant chemotherapy for breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Raynaud Disease | 2003 |
Lymph nodes in the irradiated field influence the yield of radiation-induced chromosomal aberrations in lymphocytes from breast cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Chromosome Aberrations; Cisplatin; Female; Fluorouracil; Humans; Lymph Node Excision; Lymph Nodes; Lymphocytes; Mastectomy, Segmental; Methotrexate | 2003 |
Selective estrogen receptor modulators as inhibitors of repopulation of human breast cancer cell lines after chemotherapy.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Methotrexate; Neoplasms, Hormone-Dependent; Piperidines; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Thiophenes; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2003 |
[Cancer chemotherapy in the future. Discussion].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Drug Delivery Systems; Fluorouracil; Humans; Leucovorin; Medical Oncology; Methotrexate; Neoadjuvant Therapy; Neoplasms; Palliative Care; Quality of Life | 2003 |
Reversible ovarian ablation or chemotherapy: are we ready for quality of life to guide adjuvant treatment decisions in breast cancer?
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Goserelin; Humans; Methotrexate; Quality of Life; Randomized Controlled Trials as Topic | 2003 |
Moderate neutropenia with adjuvant CMF confers improved survival in early breast cancer.
Topics: Adult; Age of Onset; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neutropenia; Prognosis; Survival Analysis | 2003 |
[A report of two cases--two patients of the extremely advanced hepatocellular carcinoma have responded completely for a long time after a combination therapy consisting of arterial chemotherapy and injection of interferon-alpha].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Fluorouracil; Hepatitis C; Humans; Infusions, Intra-Arterial; Injections, Subcutaneous; Interferon-alpha; Liver Neoplasms; Male; Methotrexate; Prognosis; Remission Induction | 2003 |
[A case of advanced gastric cancer that responded to docetaxel with low-dose 5-FU and cisplatin combination chemotherapy after becoming chemoresistant to M-FLP].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Drug Administration Schedule; Drug Resistance, Neoplasm; Fluorouracil; Humans; Leucovorin; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Stomach Neoplasms; Taxoids | 2003 |
Expression of thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase, E2F-1, Bak, Bcl-X, and Bcl-2, and clinical outcomes for gastric cancer patients treated with bolus 5-fluorouracil.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; bcl-2 Homologous Antagonist-Killer Protein; bcl-X Protein; Biomarkers, Tumor; Cell Cycle Proteins; Dihydrouracil Dehydrogenase (NADP); DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; Female; Fluorouracil; Follow-Up Studies; Humans; Immunohistochemistry; Male; Membrane Proteins; Methotrexate; Middle Aged; Multivariate Analysis; Proto-Oncogene Proteins c-bcl-2; Stomach Neoplasms; Survival Analysis; Thymidine Phosphorylase; Thymidylate Synthase; Transcription Factors; Treatment Outcome | 2004 |
Incidence and predictors of low dose-intensity in adjuvant breast cancer chemotherapy: a nationwide study of community practices.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Chi-Square Distribution; Child; Colony-Stimulating Factors; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Incidence; Logistic Models; Methotrexate; Middle Aged; Paclitaxel; Practice Patterns, Physicians'; Predictive Value of Tests; Retrospective Studies; Statistics, Nonparametric; United States | 2003 |
Is surgery necessary after complete clinical remission following neoadjuvant chemotherapy for early breast cancer?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Chi-Square Distribution; Cisplatin; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Prognosis; Radiotherapy, Adjuvant; Remission Induction; Retrospective Studies; Statistics, Nonparametric; Survival Analysis | 2003 |
Vinorelbine, methotrexate and fluorouracil (VMF) as first-line therapy in metastatic breast cancer: significance of the time between initiation of adjuvant therapy and of therapy for metastatic breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Time Factors; Vinblastine; Vinorelbine | 2004 |
[Prognostication of hematotoxicity for radio- and chemotherapy in patients with breast cancer].
Topics: Adult; Aged; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Chemotherapy, Adjuvant; Clodronic Acid; Cyclophosphamide; Female; Fluorouracil; Hematologic Diseases; Humans; Methotrexate; Middle Aged; Prognosis; Radiotherapy, Adjuvant | 2003 |
Adherence to the guidelines of the CCCE in the treatment of node-positive breast cancer patients.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Guideline Adherence; Humans; Lymphatic Metastasis; Mastectomy, Segmental; Medical Audit; Methotrexate; Middle Aged; Practice Guidelines as Topic; Retrospective Studies | 2004 |
Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate.
Topics: Alanine; Animals; Antimetabolites, Antineoplastic; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Cytosine; DNA Probes; Female; Fluorouracil; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genotype; Humans; Leucovorin; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Polymorphism, Genetic; Random Allocation; Thymidylate Synthase; Thymine; Transfection; Transplantation, Heterologous; Valine | 2004 |
Treatment of intracranial rat glioma model with implant of radiosensitizer and biomodulator drug combined with external beam radiotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Brain Neoplasms; Bromodeoxyuridine; Cell Line, Tumor; Combined Modality Therapy; Drug Combinations; Drug Implants; Fluorouracil; Glioma; Immunologic Factors; Methotrexate; Phosphonoacetic Acid; Radiation-Sensitizing Agents; Rats | 2004 |
Adjuvant chemotherapy in elderly patients with breast cancer: a survey of the Breast International Group (BIG).
Topics: Aged; Aging; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Geriatric Assessment; Health Care Surveys; Humans; Medical Oncology; Methotrexate; Patient Care Planning; Practice Patterns, Physicians'; Predictive Value of Tests | 2004 |
Using loco-regional recurrence as an indicator of the quality of breast cancer treatment.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 2004 |
Fatigue, weight gain, lethargy and amenorrhea in breast cancer patients on chemotherapy: is subclinical hypothyroidism the culprit?
Topics: Adult; Aged; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Estradiol; Fatigue; Female; Fluorouracil; Humans; Hypothyroidism; Methotrexate; Middle Aged; Prospective Studies; Sleep Stages; Thyroxine; Weight Gain | 2004 |
[A case of advanced gastric cancer with DIC treated by sequential MTX and 5-FU].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Disseminated Intravascular Coagulation; Drug Administration Schedule; Fluorouracil; Humans; Male; Methotrexate; Remission Induction; Stomach Neoplasms | 2004 |
[Two cases of breast cancer markedly responded to neoadjuvant chemoendocrine therapy (2 cycles of CMF and tamoxifen, pCR and near pCR)].
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Mastectomy, Segmental; Methotrexate; Neoadjuvant Therapy; Remission Induction; Tamoxifen | 2004 |
Differential mucin expression in colon carcinoma HT-29 clones with variable resistance to 5-fluorouracil and methotrexate.
Topics: Blotting, Northern; Blotting, Western; Clone Cells; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Methotrexate; Microscopy, Electron; Mucins; RNA, Messenger | 2004 |
Tolerance of radiotherapy and chemotherapy in elderly patients with bladder cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Male; Methotrexate; Retrospective Studies; Survival Analysis; Treatment Outcome; Urinary Bladder Neoplasms; Vinblastine | 2004 |
Hypoxia-inducible factor 1 alpha in high-risk breast cancer: an independent prognostic parameter?
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cohort Studies; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Docetaxel; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Life Tables; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Proteins; Neoplasm Staging; Paclitaxel; Prednisone; Prognosis; Receptors, Progesterone; Risk; Survival Analysis; Tamoxifen; Taxoids; Transcription Factors; Vincristine | 2004 |
Induction of a multifactorial resistance phenotype by high paclitaxel selective pressure in a human ovarian carcinoma cell line.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Flow Cytometry; Fluorouracil; Humans; Inhibitory Concentration 50; Methotrexate; Mitochondrial Proteins; Multidrug Resistance-Associated Proteins; Ovarian Neoplasms; Paclitaxel; Phenotype; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Tetrazolium Salts; Time Factors; Tubulin; Verapamil; Vinblastine | 2004 |
Prevalence and course of fatigue in breast cancer patients receiving adjuvant chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease Progression; Doxorubicin; Fatigue; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prevalence; Prospective Studies; Quality of Life | 2004 |
[A case of curatively resected gastric cancer through an effective response to chemotherapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Jejunostomy; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Invasiveness; Pancreatic Neoplasms; Peritoneal Neoplasms; Quality of Life; Stomach Neoplasms | 2004 |
Quality of adjuvant CMF chemotherapy for node-positive primary breast cancer: a population-based study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Guideline Adherence; Guidelines as Topic; Humans; Lymphatic Metastasis; Medical Oncology; Methotrexate; Middle Aged; Quality Assurance, Health Care; Radiotherapy; Retrospective Studies; Survival Analysis | 2004 |
Critical limb ischaemia associated with chemotherapy for breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fingers; Fluorouracil; Foot; Humans; Ischemia; Methotrexate; Middle Aged; Pain | 2004 |
Deleted in colon cancer protein expression in colorectal cancer metastases: a major predictor of survival in patients with unresectable metastatic disease receiving palliative fluorouracil-based chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Adhesion Molecules; Colorectal Neoplasms; DCC Receptor; Female; Fluorouracil; Gene Expression Profiling; Humans; Immunohistochemistry; Leucovorin; Male; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Palliative Care; Predictive Value of Tests; Prognosis; Receptors, Cell Surface; Retrospective Studies; Survival Analysis; Treatment Outcome; Tumor Suppressor Proteins | 2004 |
[Importance of timing of music therapy in chemotherapy of cancer patients].
Topics: Adrenocorticotropic Hormone; Adult; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; beta-Endorphin; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Dehydroepiandrosterone; Female; Fluorouracil; Humans; Hydrocortisone; Immunoradiometric Assay; Luminescent Measurements; Methotrexate; Music Therapy; Postoperative Care; Radioimmunoassay; Random Allocation; Time Factors | 2004 |
Restriction of de novo nucleotide biosynthesis interferes with clonal expansion and differentiation into effector and memory CD8 T cells.
Topics: Adoptive Transfer; Animals; CD8-Positive T-Lymphocytes; Cell Differentiation; Cytotoxicity, Immunologic; Fluorouracil; Graft vs Host Disease; Immunization; Immunologic Memory; Interferon-gamma; Methotrexate; Mice; Mice, Inbred C57BL; Mycophenolic Acid; Nucleotides | 2004 |
Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/metotrexate/5-fluorouracil, epirubicin/cyclophosphamide, epirubicin/paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Cyclophosphamide; Diphosphonates; Docetaxel; Drug Synergism; Epirubicin; Female; Fluorouracil; Humans; Ibandronic Acid; Imidazoles; In Vitro Techniques; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasms, Ductal, Lobular, and Medullary; Paclitaxel; Taxoids; Zoledronic Acid | 2004 |
[Salvianolic acid A inhibits nucleoside transport and potentiates the antitumor activity of chemotherapeutic drugs].
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Biological Transport; Caffeic Acids; Drug Synergism; Drugs, Chinese Herbal; Female; Fluorouracil; Humans; KB Cells; Lactates; Male; Methotrexate; Mice; Mitomycin; Neoplasm Transplantation; Plants, Medicinal; Salvia miltiorrhiza; Sarcoma 180; Tumor Cells, Cultured | 2004 |
Delayed-type hypersensitivity reaction with iscador M given in combination with cytotoxic chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Deoxycytidine; Female; Fluorouracil; Gemcitabine; Humans; Hypersensitivity, Delayed; Methotrexate; Plant Extracts; Plant Proteins | 2004 |
Same gain, less pain: potential patient preferences for adjuvant treatment in premenopausal women with early breast cancer.
Topics: Activities of Daily Living; Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fertility; Fluorouracil; Goserelin; Humans; Interpersonal Relations; Methotrexate; Middle Aged; Patient Satisfaction; Premenopause; Time Factors | 2004 |
Effects of folylpolyglutamate synthetase modulation on chemosensitivity of colon cancer cells to 5-fluorouracil and methotrexate.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Cell Division; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Fluorouracil; Humans; Methotrexate; Peptide Synthases; Transfection; Tumor Cells, Cultured | 2004 |
[MTX/CDDP/5-FU double modulation intra-peritoneal chemotherapy for advanced and metastatic gastric cancer--comparison with intra-aortic route and intra-venous route].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 2004 |
Adjuvant chemotherapy for lymph node-negative, estrogen receptor-negative breast cancer: a tale of three trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Odds Ratio; Prognosis; Receptors, Estrogen; Survival Analysis | 2004 |
Neoadjuvant chemotherapy with cyclophosphamide, mitoxantrone, and 5-fluorouracil in locally advanced breast cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Causality; Chemotherapy, Adjuvant; Cisplatin; Comorbidity; Disease-Free Survival; Female; Fluorouracil; Hematologic Diseases; Humans; Methotrexate; Middle Aged; Retrospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Survival Analysis; Turkey | 2005 |
Course of mental fatigue and motivation in breast cancer patients receiving adjuvant chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cognition Disorders; Cyclophosphamide; Depression; Fatigue; Female; Fluorouracil; Humans; Mastectomy; Mastectomy, Segmental; Methotrexate; Middle Aged; Motivation; Prospective Studies; Quality of Life | 2005 |
Q-TWiST analysis of cyclophosphamide, epirubicin, fluorouracil versus cyclophosphamide, methotrexate, fluorouracil treatment for premenopausal women with node-positive breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Clinical Trials, Phase III as Topic; Cyclophosphamide; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Premenopause; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome | 2005 |
Preoperative sequential chemotherapy in locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cohort Studies; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Remission Induction | 2005 |
Clinical role of multidrug resistance protein 1 expression in chemotherapy resistance in early-stage breast cancer: the Austrian Breast and Colorectal Cancer Study Group.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Austria; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Colorectal Neoplasms; Cyclophosphamide; Disease-Free Survival; Drug Resistance, Multiple; Female; Fluorouracil; Goserelin; Humans; Methotrexate; Multidrug Resistance-Associated Proteins; Neoplasms, Hormone-Dependent; Premenopause; Tamoxifen | 2005 |
A new high-performance liquid chromatographic/electrospray ionization tandem mass spectrometric method for the simultaneous determination of cyclophosphamide, methotrexate and 5-fluorouracil as markers of surface contamination for occupational exposure mo
Topics: Air Pollutants, Occupational; Calibration; Chromatography, High Pressure Liquid; Cyclophosphamide; Fluorouracil; Methotrexate; Occupational Exposure; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2005 |
[A patient with metastatic breast cancer associated with retention of pleural effusion with no response to both CMF and exemestane, whose life was saved by high-dose toremifene].
Topics: Aged; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Pleural Effusion; Remission Induction; Salvage Therapy; Toremifene | 2005 |
[Clinical analysis of resectable breast cancer: a report of 6 263 cases].
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Breast Neoplasms, Male; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Male; Mastectomy; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Rate | 2005 |
Compliance and toxicity of adjuvant CMF in elderly breast cancer patients: a single-center experience.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Hematologic Diseases; Humans; Methotrexate; Middle Aged; Patient Compliance; Radiotherapy, Adjuvant; Retrospective Studies | 2005 |
Worse survival for TP53 (p53)-mutated breast cancer patients receiving adjuvant CMF.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cohort Studies; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, p53; Genetic Markers; Humans; Methotrexate; Middle Aged; Mutation; Neoplasm Staging; Neoplasms, Hormone-Dependent; Polymerase Chain Reaction; Probability; Prognosis; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Survival Analysis; Tamoxifen | 2005 |
[Minutes of the 23th meeting of the European Society for Therapeutic Radiology and Oncology (ESTRO). Amsterdam, 24-28 October 2004].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amifostine; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Mastectomy; Methotrexate; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Radiation-Protective Agents; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Rectal Neoplasms; Time Factors | 2005 |
[Assessment of staging and prognostic scoring system for malignant trophoblastic neoplasia].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Female; Fluorouracil; Humans; Hydatidiform Mole, Invasive; Methotrexate; Neoplasm Staging; Pregnancy; Prognosis; Severity of Illness Index; Survival Rate; Treatment Outcome; Trophoblastic Neoplasms; Uterine Neoplasms | 2005 |
[Modified pharmacokinetic modulating chemotherapy for progressive gastric cancer accompanied by peritoneal dissemination].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Peritoneal Neoplasms; Stomach Neoplasms; Survival Rate; Tegafur; Uracil | 2005 |
[A case of advanced gastric cancer with bone metastasis and severe DIC responding to hypertensive subselective chemotherapy with pharmacokinetic modulating chemotherapy].
Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Signet Ring Cell; Disseminated Intravascular Coagulation; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Methotrexate; Middle Aged; Paclitaxel; Quality of Life; Stomach Neoplasms; Tegafur; Uracil | 2005 |
Long-term survival in locally advanced oral cavity cancer: an analysis of patients treated with neoadjuvant cisplatin-based chemotherapy followed by surgery.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoadjuvant Therapy; Neoplasm Staging; Sex Factors; Survival Analysis; Time Factors; Vinblastine; Vincristine | 2005 |
MRI and conservative treatment of locally advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Magnetic Resonance Imaging; Mastectomy; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Treatment Outcome | 2005 |
Predictive value of in vitro assessment of cytotoxic drug activity in advanced breast cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Survival; Cyclophosphamide; Disease Progression; Docetaxel; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Epirubicin; Female; Fluorometry; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Predictive Value of Tests; Prospective Studies; Quality Control; Retrospective Studies; Taxoids; Treatment Outcome; Tumor Cells, Cultured | 2005 |
Chemotherapy for breast cancer during pregnancy: an 18-year experience from five London teaching hospitals.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; London; Methotrexate; Neoadjuvant Therapy; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Retrospective Studies | 2005 |
Potential risk of a common hereditary thrombophilia and adjuvant chemotherapy for low-stage breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Fatal Outcome; Female; Fluorouracil; Homocysteine; Humans; Methotrexate; Middle Aged; Mutation; Risk; Thrombophilia | 2005 |
Micronucleated erythrocyte frequencies in old and new world primates: measurement of micronucleated erythrocyte frequencies in peripheral blood of Callithrix jacchus as a model for evaluating genotoxicity in primates.
Topics: Animals; Antineoplastic Agents; Callithrix; Cyclophosphamide; Cytarabine; Erythrocytes; Fluorouracil; Humans; Methotrexate; Micronuclei, Chromosome-Defective; Micronucleus Tests; Models, Animal; Mutagenicity Tests; Mutagens; Primates | 2005 |
[A case of head and neck squamous cell carcinoma suffering from acute renal failure after methotrexate administrator].
Topics: Acute Kidney Injury; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Middle Aged | 2005 |
Patterns of toxicity in older patients with breast cancer receiving adjuvant chemotherapy.
Topics: Age Factors; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Comorbidity; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Multivariate Analysis; Retrospective Studies; Risk; United States | 2005 |
IgG immune response to tumor-associated carbohydrate antigens (TF, Tn, alphaGal) in patients with breast cancer: impact of neoadjuvant chemotherapy and relation to the survival.
Topics: Adult; Aged; Aged, 80 and over; alpha-Galactosidase; Antibodies, Neoplasm; Antibody Formation; Antigens, Tumor-Associated, Carbohydrate; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Epitopes; Female; Fibroadenoma; Fluorouracil; Haptens; Humans; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Survival Rate; Thromboplastin | 2005 |
Enhanced glucose absorption in the rat small intestine following repeated doses of 5-fluorouracil.
Topics: 3-O-Methylglucose; Administration, Oral; Alkaline Phosphatase; Animals; Antimetabolites, Antineoplastic; Enzyme Activation; Fluorouracil; Glucose; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Kinetics; Male; Membrane Fluidity; Membrane Glycoproteins; Methotrexate; Microvilli; Monosaccharide Transport Proteins; Phlorhizin; Rats; Rats, Wistar; Sodium-Glucose Transporter 1; Sodium-Potassium-Exchanging ATPase | 2005 |
Herpes simplex encephalitis as a complication of adjuvant chemotherapy treatment for breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Encephalitis, Herpes Simplex; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged | 2005 |
Preparation and characterization of a biodegradable drug targeting system for anticancer drug delivery: microsphere-antibody conjugate.
Topics: Antibodies; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Line, Tumor; Cross-Linking Reagents; Drug Delivery Systems; Drug Stability; Excipients; Female; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Fluorouracil; Gelatin; Glutaral; Humans; Methotrexate; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Microspheres; Particle Size; Serum Albumin, Bovine | 2005 |
Near-final word on adjuvant chemotherapy for breast cancer is good news.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Europe; Female; Fluorouracil; Humans; Meta-Analysis as Topic; Methotrexate; Receptors, Estrogen; Trastuzumab; United States | 2005 |
[Stage IV gastric cancer patient who underwent palliative gastrectomy showing complete response to induction therapy with methotrexate plus 5-fluorouracil and secondary treatment with oral TS-1].
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Carcinoembryonic Antigen; Carcinoma, Signet Ring Cell; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Leucovorin; Lymphatic Metastasis; Methotrexate; Oxonic Acid; Palliative Care; Pyridines; Stomach Neoplasms; Tegafur | 2005 |
Breast conservation after neoadjuvant chemotherapy for stage II carcinoma of the breast.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Mastectomy; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Prospective Studies; Survival Analysis; Time Factors | 2005 |
Environmental contamination with cytotoxic drugs in healthcare using positive air pressure isolators.
Topics: Antineoplastic Agents; Cyclophosphamide; Environmental Monitoring; Equipment Contamination; Fluorouracil; Gloves, Protective; Hospitals; Humans; Ifosfamide; Methotrexate; Occupational Exposure; Pharmacies; Pressure; Protective Devices; Workplace | 2005 |
Incidence and prognostic impact of amenorrhea during adjuvant therapy in high-risk premenopausal breast cancer: analysis of a National Cancer Institute of Canada Clinical Trials Group Study--NCIC CTG MA.5.
Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Cyclophosphamide; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Humans; Incidence; Methotrexate; Middle Aged; Premenopause; Prognosis; Retrospective Studies; Risk Factors | 2005 |
HER2 overexpression as a predictive marker in a randomized trial comparing adjuvant cyclophosphamide/methotrexate/5-fluorouracil with epirubicin in patients with stage I/II breast cancer: long-term results.
Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Genes, erbB-2; Humans; Mastectomy; Methotrexate; Middle Aged; Neoplasm Staging; Predictive Value of Tests; Prognosis; Randomized Controlled Trials as Topic; Retrospective Studies; Survival Analysis | 2005 |
Effect of creatinine clearance on patterns of toxicity in older patients receiving adjuvant chemotherapy for breast cancer.
Topics: Age Factors; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Creatinine; Cyclophosphamide; Female; Fluorouracil; Hematologic Diseases; Humans; Methotrexate; Predictive Value of Tests; Retrospective Studies; Time Factors | 2005 |
Electrophysiological correlates of information processing in breast-cancer patients treated with adjuvant chemotherapy.
Topics: Adult; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Case-Control Studies; Chemotherapy, Adjuvant; Cognition Disorders; Cyclophosphamide; Electroencephalography; Evoked Potentials; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neuropsychological Tests; Neurotoxicity Syndromes; Reaction Time | 2005 |
Identifying good prognosis group of breast cancer patients with 1-3 positive axillary nodes for adjuvant cyclophosphamide, methotrexate and 5-fluorouracil (CMF) chemotherapy.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasms, Ductal, Lobular, and Medullary; Prognosis; Prospective Studies; Receptors, Estrogen; Retrospective Studies; Survival Rate; Time Factors; Treatment Outcome | 2005 |
[Treatment strategy for primary gastric cancer with peritoneal dissemination].
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Combinations; Fluorouracil; Gastrectomy; Humans; Lymph Node Excision; Methotrexate; Oxonic Acid; Paclitaxel; Peritoneal Neoplasms; Pyridines; Stomach Neoplasms; Survival Rate; Tegafur | 2005 |
[Case report--postoperative continuous intraarterial infusion of small doses of 5-FU successfully controlled residual tumor and liver metastasis of stage IV gastric cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Doxorubicin; Drug Combinations; Floxuridine; Fluorouracil; Gastrectomy; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Mitomycin; Neoplasm Staging; Picibanil; Proteoglycans; Stomach Neoplasms; Tegafur; Uracil | 2005 |
Adjuvant chemotherapy in 780 patients with early breast cancer: 10-year data from Saudi Arabia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Paclitaxel; Prognosis; Radiotherapy, Adjuvant; Retrospective Studies; Saudi Arabia; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome | 2005 |
[Safety and efficacy of hypotonic CDDP intraperitoneal administration for gastric cancer with peritoneal dissemination].
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Cisplatin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hypotonic Solutions; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Neoplasm Seeding; Peritoneal Neoplasms; Stomach Neoplasms | 2005 |
Adjuvant chemotherapy for Merkel cell carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Merkel Cell; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Disease-Free Survival; Etoposide; Extremities; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Peripheral Blood Stem Cell Transplantation; Radiotherapy, Adjuvant; Reoperation; Skin Neoplasms; Treatment Outcome | 2005 |
[Clinical analysis of 67 patients with brain metastases from breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Cranial Irradiation; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Survival Rate | 2005 |
Dose-dense adjuvant chemotherapy for node-positive breast cancer in women 60 years and older: feasibility and tolerability in a subset of patients in a randomized trial.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Epirubicin; Feasibility Studies; Female; Filgrastim; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Paclitaxel; Randomized Controlled Trials as Topic; Recombinant Proteins; Retrospective Studies | 2006 |
Neoadjuvant interstitial high-dose-rate (HDR) brachytherapy combined with systemic chemotherapy in patients with breast cancer.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Breast; Breast Neoplasms; Carcinoma, Ductal; Carcinoma, Lobular; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Docetaxel; Dose Fractionation, Radiation; Doxorubicin; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Retrospective Studies; Risk Factors; Taxoids; Time Factors; Tomography, X-Ray Computed; Treatment Outcome | 2006 |
Cause-specific mortality in long-term survivors of breast cancer: A 25-year follow-up study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiovascular Diseases; Cause of Death; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Methotrexate; Middle Aged; Neoplasms, Second Primary; Netherlands; Proportional Hazards Models; Risk; Survivors | 2006 |
Linear quadratic modeling of increased late normal-tissue effects in special clinical situations.
Topics: Aged; Algorithms; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Fluorouracil; Humans; Linear Models; Lymphoma; Methotrexate; Radiation Tolerance; Relative Biological Effectiveness; Surgical Procedures, Operative | 2006 |
Assessment of ovarian failure and osteoporosis in premenopausal breast cancer survivors.
Topics: Absorptiometry, Photon; Administration, Oral; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Density; Breast Neoplasms; Calcium; Contraceptives, Oral; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Utilization Review; Estradiol; Female; Fluorouracil; Follicle Stimulating Hormone; Follow-Up Studies; Goserelin; Humans; Medical Records; Menstruation Disturbances; Methotrexate; Osteoporosis, Postmenopausal; Premenopause; Primary Ovarian Insufficiency; Process Assessment, Health Care; Retrospective Studies; Survivors; Tamoxifen; Time Factors | 2005 |
Continued survival of more than ten years, without resection of metastatic disease, in patients with metastatic colorectal cancer treated with biomodulated fluorouracil: report of two cases.
Topics: Acetates; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colorectal Neoplasms; Female; Fluorouracil; Humans; Immunologic Factors; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Phosphonoacetic Acid; Remission Induction; Uridine; Vitamin B Complex | 2006 |
Incidence, time course, and determinants of menstrual bleeding after breast cancer treatment: a prospective study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Logistic Models; Menstruation; Methotrexate; Multivariate Analysis; Neoplasm Staging; Odds Ratio; Ovary; Premenopause; Prospective Studies; Surveys and Questionnaires; Time Factors | 2006 |
[A case of recurrent breast cancer with life-threatening multiple lung metastasis markedly responding to CMF as third-line chemotherapy].
Topics: Adult; Anthracyclines; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Lung Neoplasms; Lymphangitis; Methotrexate; Quality of Life; Remission Induction; Tamoxifen; Taxoids | 2006 |
Panmucositis and chemosensitisation associated with betel quid chewing during dose-dense adjuvant breast cancer chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Areca; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Docetaxel; Doxorubicin; Female; Fluorouracil; Herb-Drug Interactions; Humans; Mastication; Methotrexate; Middle Aged; Mucositis; Taxoids | 2006 |
Eosinophilic pustular folliculitis induced by chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Eruptions; Eosinophilia; Female; Fluorouracil; Folliculitis; Humans; Methotrexate; Middle Aged; Scalp Dermatoses | 2006 |
Concurrent radiotherapy does not affect adjuvant CMF delivery but is associated with increased toxicity in women with early breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Infusions, Intravenous; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Radiotherapy, Adjuvant; Retrospective Studies | 2006 |
Cyclin D1 antisense oligodexoyneucleotides inhibits growth and enhances chemosensitivity in gastric carcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chemoreceptor Cells; Cisplatin; Cyclin D1; Dose-Response Relationship, Drug; Fluorouracil; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Oligodeoxyribonucleotides, Antisense; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Tetrahydrofolate Dehydrogenase; Thymidine Phosphorylase; Thymidylate Synthase; Transfection | 2006 |
Application of intrathecal trastuzumab (Herceptintrade mark) for treatment of meningeal carcinomatosis in HER2-overexpressing metastatic breast cancer.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Capecitabine; Deoxycytidine; Female; Fluorouracil; Humans; Meningeal Neoplasms; Methotrexate; Receptor, ErbB-2; Trastuzumab | 2006 |
A case of breast carcinoma late metastasis to the kidney.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Kidney Neoplasms; Mastectomy; Methotrexate; Time Factors | 2006 |
Genomic alterations identified by array comparative genomic hybridization as prognostic markers in tamoxifen-treated estrogen receptor-positive breast cancer.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Chromosomes, Artificial, Bacterial; Cluster Analysis; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; DNA, Neoplasm; Estrogen Receptor Modulators; Estrogens; Female; Fluorouracil; Humans; Life Tables; Mastectomy; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Prognosis; Radiotherapy, Adjuvant; Receptors, Estrogen; Tamoxifen | 2006 |
Concurrent chemoradiotherapy with cisplatin, 5-fluorouracil, methotrexate, and leucovorin in patients with advanced resectable squamous cell carcinoma of the larynx and hypopharynx.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Humans; Hypopharynx; Laryngeal Neoplasms; Leucovorin; Male; Methotrexate; Middle Aged; Pharyngeal Neoplasms; Radiotherapy, Adjuvant; Survival Analysis; Treatment Outcome; Vitamin B Complex | 2006 |
Colony-stimulating factor-1 antibody reverses chemoresistance in human MCF-7 breast cancer xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cyclophosphamide; DNA Primers; Down-Regulation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Humans; Immunoglobulin Fragments; Macrophage Colony-Stimulating Factor; Matrix Metalloproteinases; Methotrexate; Mice; Receptor, Macrophage Colony-Stimulating Factor; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2006 |
Neoadjuvant treatment of gastric cancer with peritoneal dissemination.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemotherapy, Adjuvant; Docetaxel; Female; Fluorouracil; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Peritoneal Neoplasms; Quality of Life; Stomach Neoplasms; Survival Rate; Taxoids; Treatment Outcome | 2006 |
Keratoacanthoma centrifugum marginatum: response to topical 5-fluorouracil.
Topics: Aged, 80 and over; Dermatologic Agents; Female; Fluorouracil; Humans; Keratoacanthoma; Leg; Methotrexate; Retreatment; Skin; Skin Diseases; Treatment Failure; Treatment Outcome | 2006 |
In regards to Arcangeli et al. (Int J Radiat Oncol Biol Phys 2006;64:161-167).
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant | 2006 |
[Establishment of a multidrug-resistant cell line BEL-7402/5-FU of human hepatocellular carcinoma and its biological characteristics].
Topics: Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Vincristine | 2006 |
TS-1 as first-line therapy for gastric linitis plastica: historical control study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Female; Fluorouracil; Humans; Linitis Plastica; Male; Methotrexate; Middle Aged; Mitomycin; Oxonic Acid; Pyridines; Retrospective Studies; Stomach Neoplasms; Survival Analysis; Tegafur | 2006 |
Effect of tamoxifen after chemotherapy in hormone receptor-positive, node-negative breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Staging; Receptors, Steroid; Tamoxifen | 2006 |
Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cisplatin; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Linear Models; Lymphatic Metastasis; Methotrexate; Middle Aged; Mitomycins; Neoplasm Proteins; Neoplasm Recurrence, Local; Odds Ratio; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; Risk Assessment; Risk Factors; Secondary Prevention; Tamoxifen | 2006 |
Recurrent gestational trophoblastic tumor: management and risk factors for recurrence.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta Subunit, Human; Dactinomycin; Etoposide; Female; Fluorouracil; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Pregnancy; Retrospective Studies; Risk Factors; Vincristine | 2006 |
Expression of the high-affinity fluoropyrimidine-preferring nucleoside transporter hCNT1 correlates with decreased disease-free survival in breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Membrane Transport Proteins; Methotrexate; Middle Aged; Predictive Value of Tests; Prognosis | 2006 |
A proposed clinical test for monitoring fluoropyrimidine therapy: detection and stability of thymidylate synthase ternary complexes.
Topics: Animals; Female; Fluorouracil; Folic Acid Antagonists; Humans; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Saccharomyces cerevisiae; Tetrahydrofolates; Thymidylate Synthase; Time Factors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2006 |
Combination chemotherapy with 5-fluorouracil, methotrexate and etoposide for patients with high-risk gestational trophoblastic tumors: a report based on our 11-year clinical experiences.
Topics: Antineoplastic Combined Chemotherapy Protocols; China; Drug Resistance, Neoplasm; Etoposide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Survival Analysis; Treatment Outcome; Trophoblastic Neoplasms; Uterine Neoplasms | 2006 |
[Clinicopathological characteristics of gastric cancer in elderly patients].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Humans; Hypertension; Leucovorin; Male; Methotrexate; Quality of Life; Retrospective Studies; Stomach Neoplasms; Survival Rate | 2006 |
Tolerability and safety of classic cyclophosphamide, methotrexate, and fluorouracil treatment in Japanese patients with early breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Feasibility Studies; Female; Fluorouracil; Humans; Japan; Maximum Tolerated Dose; Methotrexate; Middle Aged | 2006 |
The effects of the anti-cancer drugs, methotrexate and 5-fluorouracil, on cognitive function in mice.
Topics: Animals; Antineoplastic Agents; Cognition; Female; Fluorouracil; Learning; Methotrexate; Mice; Mice, Inbred BALB C | 2006 |
Concurrent radiotherapy and capecitabine, followed by high-dose methotrexate consolidation, provided effective palliation in a patient with leptomeningeal metastases from breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Meningeal Neoplasms; Methotrexate; Palliative Care | 2007 |
[Treatment of malignant ovarian tumours in Georgia in 1990-2000].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Georgia (Republic); Humans; Hysterectomy; Methotrexate; Ovarian Neoplasms; Ovariectomy; Treatment Outcome | 2006 |
Gene expression profilers and conventional clinical markers to predict distant recurrences for premenopausal breast cancer patients after adjuvant chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; DNA, Complementary; Female; Fluorouracil; Gene Expression Profiling; Humans; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Predictive Value of Tests; Premenopause; RNA; ROC Curve | 2006 |
A prospective study of adjuvant CMF in males with node positive breast cancer: 20-year follow-up.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms, Male; Chemotherapy, Adjuvant; Cyclophosphamide; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; SEER Program | 2007 |
A patient with breast cancer with hepatic metastases and a complete response to herceptin as monotherapy.
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Neoplasms; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Karnofsky Performance Status; Liver Neoplasms; Lymphatic Metastasis; Mastectomy, Modified Radical; Methotrexate; Radiotherapy Dosage; Receptor, ErbB-2; Tamoxifen; Time Factors; Tomography, X-Ray Computed; Trastuzumab; Treatment Outcome | 2006 |
Adjuvant chemotherapy for breast cancer--30 years later.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Methotrexate | 2006 |
Proteomic analysis identifies candidate proteins associated with distant recurrences in breast cancer after adjuvant chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cohort Studies; Combined Modality Therapy; DNA, Complementary; Electrophoresis, Gel, Two-Dimensional; Female; Fluorouracil; Gels; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Molecular Weight; Neoplasm Proteins; Neoplasm Recurrence, Local; Oligonucleotide Array Sequence Analysis; Proteomics | 2007 |
Recurrence rates after DCE-MRI image guided planning for breast-conserving surgery following neoadjuvant chemotherapy for locally advanced breast cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; England; Female; Fluorouracil; Follow-Up Studies; Humans; Immunosuppressive Agents; Incidence; Magnetic Resonance Imaging; Mastectomy; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Preoperative Care; Retrospective Studies; Treatment Outcome | 2007 |
[A case of long-term survival of 3-years 4 months after combination chemotherapy of MTX, 5-FU and low-dose CDDP (MFP) for type 4 gastric cancer with pleuritis, peritoneal dissemination and Krukenberg tumor].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Gastrectomy; Humans; Hysterectomy; Krukenberg Tumor; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Neoplasms, Multiple Primary; Ovarian Neoplasms; Pancreatectomy; Peritoneal Neoplasms; Pleurisy; Stomach Neoplasms; Survivors | 2006 |
Primary tumor levels of tissue inhibitor of metalloproteinases-1 are predictive of resistance to chemotherapy in patients with metastatic breast cancer.
Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Sensitivity and Specificity; Tissue Inhibitor of Metalloproteinase-1; Treatment Outcome | 2006 |
[Breast cancer in young women in the south of Tunisia].
Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mammography; Mastectomy; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Staging; Prognosis; Radiotherapy, Adjuvant; Retrospective Studies; Risk Factors; Sensitivity and Specificity; Survival Analysis; Time Factors; Treatment Outcome; Tunisia | 2006 |
Alkaline comet assay study with breast cancer patients: evaluation of baseline and chemotherapy-induced DNA damage in non-target cells.
Topics: Adult; Aged; Anthracyclines; Antineoplastic Agents; Breast Neoplasms; Cell Nucleus; Comet Assay; Cyclophosphamide; DNA; DNA Damage; Female; Fluorouracil; Humans; Leukocytes; Methotrexate; Middle Aged; Statistics as Topic | 2006 |
Feasibility of concurrent adjuvant chemotherapy and radiotherapy after breast-conserving surgery in early breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Feasibility Studies; Female; Fluorouracil; Humans; Infusions, Intravenous; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Staging; Prospective Studies; Radiotherapy Dosage; Radiotherapy, Adjuvant | 2007 |
[MTX-CDDP-5-FU double modulation intra aortic chemotherapy for advanced and metastatic gastric cancer--a comparison with an intra venous route].
Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta; Cisplatin; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 2006 |
The contribution of Gianni Bonadonna to the history of chemotherapy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms; Cisplatin; Dacarbazine; Doxorubicin; Female; Fluorouracil; History, 20th Century; Hodgkin Disease; Humans; Italy; Methotrexate; Neoplasms; Vinblastine | 2007 |
HER-2/neu status and response to CMF: retrospective study in a series of operable breast cancer treated with primary CMF chemotherapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Gene Amplification; Genes, erbB-2; Humans; Mammography; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Survival Analysis | 2007 |
Bio-pathologic characteristics related to chromosome 11 aneusomy and cyclin D1 gene status in surgically resected stage I and II breast cancer: Identification of an adverse prognostic profile.
Topics: Adenocarcinoma; Adult; Aged; Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Chromosomes, Human, Pair 11; Cyclin D1; Cyclophosphamide; Female; Fluorouracil; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Staging; Survival Analysis; Survival Rate | 2007 |
Anticipatory nausea: the role of individual differences related to sensory perception and autonomic reactivity.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Arousal; Autonomic Nervous System; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Cytarabine; Epirubicin; Female; Fluorouracil; Humans; Individuality; Methotrexate; Middle Aged; Perception; Radiotherapy, Adjuvant; Sick Role; Statistics as Topic; Vomiting, Anticipatory | 2007 |
Neoadjuvant chemotherapy in advanced penile carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Penile Neoplasms; Treatment Outcome; Vincristine | 2007 |
Editorial comment on: Neoadjuvant chemotherapy in advanced penile carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Penile Neoplasms; Treatment Outcome; Vincristine | 2007 |
[Outcome of gestational trophoblastic neoplasia patients with residual lung tumor after completion of treatment].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta Subunit, Human; Female; Fluorouracil; Gestational Trophoblastic Disease; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm, Residual; Pregnancy; Prognosis; Retrospective Studies | 2007 |
Adjuvant therapy for early breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Tamoxifen | 2007 |
Male breast cancer with mandibular metastasis. A case report.
Topics: Aged; Androstadienes; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Carcinoma, Ductal, Breast; Cortisone; Cyclophosphamide; Diphosphonates; Docetaxel; Fatal Outcome; Fluorouracil; Furosemide; Humans; Imidazoles; Liver Neoplasms; Male; Mandibular Neoplasms; Mastectomy, Modified Radical; Methotrexate; Omeprazole; Osteolysis; Phenobarbital; Taxoids; Toremifene; Vinblastine; Vinorelbine; Zoledronic Acid | 2007 |
Effect of adjuvant systemic treatment on cosmetic outcome and late normal-tissue reactions after breast conservation.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Cyclophosphamide; Endpoint Determination; Female; Fibrosis; Fluorouracil; Humans; Logistic Models; Mastectomy, Segmental; Methotrexate; Middle Aged; Pigmentation; Radiotherapy; Randomized Controlled Trials as Topic; Tamoxifen; Telangiectasis | 2007 |
Tattooing breast cancers treated with neoadjuvant chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Axilla; Biopsy, Needle; Breast Neoplasms; Charcoal; Chemotherapy, Adjuvant; Cyclophosphamide; Diffusion; Doxorubicin; Female; Fluorouracil; Humans; Hydrogen-Ion Concentration; Injections, Intralesional; Mastectomy, Segmental; Methotrexate; Particle Size; Suspensions; Treatment Outcome; Vincristine | 2007 |
Sequential combination chemotherapy in human breast cancer: a basis for increased antineoplastic activity and bone marrow protection.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Bone Marrow Cells; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Female; Flow Cytometry; Fluorouracil; Humans; Methotrexate; Tamoxifen | 2007 |
The effect of chemotherapy on Ki-67, Bcl-2 and Bak expression in primary tumors and lymph node metastases of breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; bcl-2 Homologous Antagonist-Killer Protein; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Cyclophosphamide; Female; Fluorouracil; Humans; Ki-67 Antigen; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Preoperative Care; Prognosis; Proto-Oncogene Proteins c-bcl-2 | 2007 |
Polymorphism of the DNA repair enzyme XRCC1 is associated with treatment prediction in anthracycline and cyclophosphamide/methotrexate/5-fluorouracil-based chemotherapy of patients with primary invasive breast cancer.
Topics: Anthracyclines; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; DNA Repair; DNA-Binding Proteins; Female; Fluorouracil; Haplotypes; Humans; Methotrexate; Pharmacogenetics; Polymorphism, Single Nucleotide; Retrospective Studies; X-ray Repair Cross Complementing Protein 1 | 2007 |
Tumour dormancy in breast cancer: an update.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm, Residual; Recurrence; Time Factors | 2007 |
Can biology trump anatomy? Do all node-positive patients with breast cancer need chemotherapy?
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Fluorouracil; Humans; Leuprolide; Lymphatic Metastasis; Methotrexate; Patient Selection; Selective Estrogen Receptor Modulators; Tamoxifen | 2007 |
Influence of thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms on the disease-free survival of breast cancer patients receiving adjuvant 5-fluorouracil/methotrexate-based therapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Electrophoresis, Agar Gel; Epirubicin; Female; Fluorouracil; Genotype; Humans; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Polymerase Chain Reaction; Polymorphism, Genetic; Predictive Value of Tests; Recurrence; Retrospective Studies; Thymidylate Synthase | 2007 |
The use of G-CSF during first line chemotherapy adversely affects the yield of PBSC mobilization in non-Hodgkin's lymphoma patients.
Topics: Adolescent; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Humans; Leukapheresis; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Retrospective Studies; Vincristine | 2002 |
Diabetes insipidus revealing an isolated pituitary stalk metastasis of breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Combined Modality Therapy; Cortisone; Cyclophosphamide; Deamino Arginine Vasopressin; Diabetes Insipidus, Neurogenic; Female; Fluorouracil; Humans; Hypopituitarism; Mastectomy, Modified Radical; Methotrexate; Pituitary Neoplasms; Radiotherapy, Conformal; Tamoxifen; Thyroxine | 2007 |
One more change of paradigm in breast cancer treatment. Postmastectomy radiotherapy for patients with one to three lymph node metastases?
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Postoperative Care; Prognosis; Survival Rate; Tamoxifen | 2007 |
An increase in cell number at completion of therapy may develop as an indicator of early relapse: quantification of circulating epithelial tumor cells (CETC) for monitoring of adjuvant therapy in breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Cell Count; Chemotherapy, Adjuvant; Cohort Studies; Cyclophosphamide; Epirubicin; Epithelial Cells; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplastic Cells, Circulating; Prognosis; Remission Induction; Survival Rate; Tamoxifen; Taxoids | 2008 |
[Therapeutic strategy for type 4 gastric cancer from the clinical oncologist standpoint].
Topics: Adenocarcinoma, Scirrhous; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Male; Methotrexate; Middle Aged; Oxonic Acid; Paclitaxel; Prognosis; Stomach Neoplasms; Survival Rate; Tegafur | 2007 |
Cytotoxic drug-induced, p53-mediated upregulation of caspase-8 in tumor cells.
Topics: Antineoplastic Agents; Apoptosis; Caspase 8; Caspase Inhibitors; Cell Line, Tumor; Drug Resistance, Neoplasm; Fluorouracil; Humans; Methotrexate; RNA, Messenger; TNF-Related Apoptosis-Inducing Ligand; Tumor Suppressor Protein p53; Up-Regulation | 2008 |
Delayed leukoencephalopathy with stroke-like presentation in chemotherapy recipients.
Topics: Adult; Aged; Antineoplastic Agents; Brain; Brain Edema; Capecitabine; Dementia, Vascular; Deoxycytidine; Diffusion Magnetic Resonance Imaging; Energy Metabolism; Female; Fluorouracil; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Infusions, Intravenous; Injections, Spinal; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neoplasms; Nerve Fibers, Myelinated; Neurologic Examination; Registries; Remission, Spontaneous; Stroke; Tegafur | 2008 |
[Diagnosis and prognosis study of breast carcinoma with micropapillary component].
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Papillary; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Liver Neoplasms; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Proportional Hazards Models; Radiotherapy, Adjuvant; Retrospective Studies; Survival Rate; Tamoxifen | 2007 |
[Lactoferrin reduces physiological dysfunctions of goldfish induced by chemotherapeutic agents].
Topics: Animals; Antimetabolites, Antineoplastic; Fluorouracil; Goldfish; Lactoferrin; Methotrexate; Premedication; Time Factors | 2007 |
[Neoadjuvant and adjuvant chemotherapy in patients with advanced penile cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Fluorouracil; Humans; Ifosfamide; Lymph Node Excision; Lymphatic Metastasis; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Staging; Penile Neoplasms; Penis; Survival Rate; Taxoids; Treatment Outcome | 2007 |
[Medical treatment of early breast cancer: chemotherapy].
Topics: Adult; Anthracyclines; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Taxoids | 2007 |
The nucleoside and nucleotide mixture (OG-VI) rescues intestinal-like epithelial cells from the cytotoxicity of chemotherapeutic agents.
Topics: Antineoplastic Agents; Caco-2 Cells; Cell Cycle; Cell Proliferation; Cell Survival; Epithelial Cells; Fluorouracil; Humans; Intestines; Mercaptopurine; Methotrexate; Nucleosides; Nucleotides | 2007 |
Ad-PUMA sensitizes drug-resistant choriocarcinoma cells to chemotherapeutic agents.
Topics: Adenoviridae; Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Growth Processes; Cell Line, Tumor; Choriocarcinoma; Combined Modality Therapy; Drug Resistance, Neoplasm; Etoposide; Female; Fluorouracil; Genetic Therapy; Humans; Methotrexate; Mice; Mice, Nude; Proto-Oncogene Proteins; RNA, Messenger; Tumor Suppressor Protein p53; Uterine Neoplasms; Xenograft Model Antitumor Assays | 2007 |
Effect of radiation dose on local control in breast cancer.
Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Radiation; Female; Fluorouracil; Humans; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy; Radiotherapy Dosage; Risk | 2008 |
[Postoperative radiotherapy of the chest wall in patients with male breast cancer].
Topics: Actuarial Analysis; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms, Male; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Fluorouracil; Follow-Up Studies; Humans; Lymph Node Excision; Lymphatic Metastasis; Male; Mastectomy, Modified Radical; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Radioisotope Teletherapy; Radiotherapy, Adjuvant; Tamoxifen; Thoracic Wall | 2007 |
[Systemic therapy of male breast cancer].
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms, Male; Combined Modality Therapy; Cyclophosphamide; Estradiol; Fluorouracil; Fulvestrant; Humans; Male; Methotrexate; Orchiectomy; Randomized Controlled Trials as Topic; Survival Rate; Tamoxifen; Treatment Outcome | 2007 |
Chemotherapy-induced nausea, vomiting, and fatigue--the role of individual differences related to sensory perception and autonomic reactivity.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Arousal; Autonomic Nervous System; Awareness; Biological Availability; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Fatigue; Female; Fluorouracil; Humans; Individuality; Methotrexate; Middle Aged; Nausea; Personality Inventory; Risk Factors; Sensory Thresholds; Sick Role; Somatoform Disorders; Statistics as Topic; Vomiting | 2007 |
[Clinical analysis of 108 cases with adenocarcinoma Barretts's esophagus].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Barrett Esophagus; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Esophageal Neoplasms; Esophagectomy; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Mitomycin; Neoplasm Staging; Postoperative Period; Prognosis; Radiotherapy, High-Energy; Retrospective Studies; Survival Analysis; Treatment Outcome | 2007 |
Expression level of beta protein 1 mRNA in Chinese breast cancer patients: a potential molecular marker for poor prognosis.
Topics: Adult; Aged; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Goserelin; Homeodomain Proteins; Humans; Methotrexate; Mice; Mice, SCID; Middle Aged; Prognosis; RNA, Messenger; Tamoxifen; Transcription Factors | 2008 |
[Results of a study on fatigue in breast cancer patients receiving adjuvant chemotherapy: the first four days after treatment are the worst].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Nursing Research; Cohort Studies; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Fatigue; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Netherlands | 2007 |
[Two cases of stage IV gastric cancer who underwent total gastrectomy and achieved long-term survival by sequential chemotherapy].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Immunosuppressive Agents; Irinotecan; Male; Methotrexate; Middle Aged; Oxonic Acid; Paclitaxel; Stomach Neoplasms; Tegafur | 2007 |
Effect of systemic adjuvant treatment on risk for contralateral breast cancer in the Women's Environment, Cancer and Radiation Epidemiology Study.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Case-Control Studies; Chemotherapy, Adjuvant; Confounding Factors, Epidemiologic; Cyclophosphamide; Doxorubicin; Estrogen Receptor Modulators; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasms, Second Primary; Ovary; Radiotherapy, Adjuvant; Research Design; Risk Assessment; Tamoxifen; Treatment Outcome | 2008 |
Combined systemic therapy and radiotherapy for bladder cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carboplatin; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Cystectomy; Deoxycytidine; Fluorouracil; Gemcitabine; Humans; Methotrexate; Neoplasm Staging; Paclitaxel; Prospective Studies; Radiation-Sensitizing Agents; Randomized Controlled Trials as Topic; Salvage Therapy; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms; Vinblastine | 2007 |
HER2 over-expression and response to different chemotherapy regimens in breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Receptor, ErbB-2 | 2008 |
Lessons from the initial adjuvant cyclophosphamide, methotrexate, and fluorouracil studies in operable breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate | 2008 |
Efficacy of primary systemic chemotherapy regimen containing anthracyclines with/without taxanes in comparison to CMF in women with early breast cancer.
Topics: Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoadjuvant Therapy; Retrospective Studies; Survival Analysis; Taxoids | 2007 |
Improving outcomes for patients with hormone receptor-positive breast cancer: back to the drawing board.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Ki-67 Antigen; Methotrexate; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Treatment Outcome | 2008 |
Predictive value of tumor Ki-67 expression in two randomized trials of adjuvant chemoendocrine therapy for node-negative breast cancer.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Ki-67 Antigen; Logistic Models; Methotrexate; Middle Aged; Multicenter Studies as Topic; Predictive Value of Tests; Prognosis; Randomized Controlled Trials as Topic; Retrospective Studies; Tamoxifen; Treatment Outcome | 2008 |
Influence of physiologic hormonal modification and of hormonal treatment in a patient with a history of migraine with aura.
Topics: Amitriptyline; Analgesics; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Contraceptives, Oral, Hormonal; Cyclophosphamide; Endometriosis; Female; Flunarizine; Fluorouracil; Gonadotropin-Releasing Hormone; Humans; Methotrexate; Middle Aged; Migraine with Aura; Pregnancy; Selective Estrogen Receptor Modulators; Tamoxifen; Triptorelin Pamoate | 2008 |
Comparison among different classification systems regarding the pathological response of preoperative chemotherapy in relation to the long-term outcome.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Docetaxel; Doxorubicin; Drug Monitoring; Estrogens; Female; Fluorouracil; Follow-Up Studies; Humans; Japan; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Paclitaxel; Progesterone; Prognosis; Retrospective Studies; Taxoids; Trastuzumab; Treatment Outcome | 2009 |
Evidence from nonrandomized studies: a case study on the estimation of causal effects.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Causality; Confounding Factors, Epidemiologic; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Germany; Humans; Methotrexate; Randomized Controlled Trials as Topic; Regression Analysis; Selection Bias | 2008 |
Interactions between treatment and continuous covariates: a step toward individualizing therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Interferon-alpha; Kaplan-Meier Estimate; Kidney Neoplasms; Leukocyte Count; Methotrexate; Models, Statistical; Odds Ratio; Predictive Value of Tests; Prognosis; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Treatment Outcome | 2008 |
Is the pathobiology of chemotherapy-induced alimentary tract mucositis influenced by the type of mucotoxic drug administered?
Topics: Animals; Antineoplastic Agents; Camptothecin; Colon; Female; Fluorouracil; Immunohistochemistry; Interleukin-1; Interleukin-6; Intestinal Mucosa; Irinotecan; Jejunum; Methotrexate; Mouth Mucosa; Mucositis; NF-kappa B; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha | 2009 |
Loss of retinoblastoma tumor suppressor protein makes human breast cancer cells more sensitive to antimetabolite exposure.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chemotherapy, Adjuvant; Drug Resistance, Neoplasm; Female; Flow Cytometry; Fluorouracil; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Methotrexate; Middle Aged; Prognosis; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference | 2008 |
Treatment options for muscle-invasive urothelial cancer for patients who were not eligible for cystectomy or neoadjuvant chemotherapy with methotrexate, vinblastine, doxorubicin, and cisplatin: report of Southwest Oncology Group Trial 8733.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cystectomy; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Muscle Neoplasms; Neoadjuvant Therapy; Prognosis; Survival Rate; Treatment Outcome; Urinary Bladder Neoplasms; Vinblastine | 2008 |
Effects of chemotherapeutic agents 5-fluorouracil and methotrexate alone and combined in a mouse model of learning and memory.
Topics: Animals; Antimetabolites, Antineoplastic; Conditioning, Operant; Drug Interactions; Fluorouracil; Food; Injections, Intraperitoneal; Learning; Male; Memory; Methotrexate; Mice; Motivation; Muscarinic Antagonists; Piperazines; Reinforcement Schedule; Reward; Scopolamine; Serotonin Receptor Agonists | 2008 |
[Treatment of advanced maxillary sinus squamous carcinoma: an analysis of 92 cases].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Male; Maxillary Sinus; Maxillary Sinus Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Proportional Hazards Models; Radiotherapy, High-Energy; Retrospective Studies; Survival Rate; Young Adult | 2008 |
[A case of advanced gastric cancer with peritoneal metastasis successfully treated over 19 months with postoperative chemotherapy after non-curative surgery].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Irinotecan; Methotrexate; Oxonic Acid; Paclitaxel; Peritoneal Neoplasms; Stomach Neoplasms; Tegafur | 2008 |
Persistent neurocognitive problems after adjuvant chemotherapy for breast cancer.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Cognition; Cognition Disorders; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neuropsychological Tests; Treatment Outcome | 2008 |
[Adjuvant chemotherapy as a component of complex treatment for skin melanoma].
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Dacarbazine; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Lymph Node Excision; Male; Melanoma; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; Radiotherapy, Adjuvant; Skin Neoplasms; Survival Analysis; Treatment Outcome; Vincristine | 2008 |
Serum levels of NFkappaB and pro-inflammatory cytokines following administration of mucotoxic drugs.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cytokines; Epithelium; Female; Fluorouracil; Gastrointestinal Tract; Gene Expression Regulation; Inflammation; Interleukin-1beta; Interleukin-6; Irinotecan; Methotrexate; NF-kappa B; Rats; Tumor Necrosis Factor-alpha | 2008 |
[Outpatient chemotherapy and oncology network : Onco Pays-de-la-Loire experiment].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Deoxycytidine; Female; Fluorouracil; France; Gemcitabine; Home Care Services; Humans; Male; Methotrexate; Middle Aged; Neoplasms; Trastuzumab | 2008 |
Oral mucosal lesions, microbial changes, and taste disturbances induced by adjuvant chemotherapy in breast cancer patients.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Candidiasis, Oral; Chemotherapy, Adjuvant; Cyclophosphamide; Dental Plaque Index; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Gingivitis; Humans; Lactobacillus; Methotrexate; Middle Aged; Mouth; Mouth Diseases; Prospective Studies; Purpura; Streptococcus mutans; Taste Disorders | 2008 |
Late cardiac effects of adjuvant radiotherapy and chemotherapy in early breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Heart; Heart Failure; Humans; Methotrexate; Middle Aged; Prognosis; Receptor, ErbB-2; Survival Rate; Survivors; Tamoxifen; Ventricular Dysfunction, Left | 2008 |
Methotrexate and leucovorin double-modulated 5-fluorouracil combined with cisplatin (MPFL) in metastatic/recurrent head and neck cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Treatment Outcome; Vitamin B Complex | 2008 |
New insight into epirubicin cardiac toxicity: competing risks analysis of 1097 breast cancer patients.
Topics: Adult; Age Factors; Aged; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Denmark; Disease Susceptibility; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Heart; Heart Failure; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Proportional Hazards Models; Radiotherapy, Adjuvant; Retrospective Studies; Risk Factors; Severity of Illness Index; Tamoxifen; Vindesine | 2008 |
Chemoradiotherapy laryngeal preservation for advanced hypopharyngeal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Hypopharyngeal Neoplasms; Larynx; Male; Methotrexate; Middle Aged; Retrospective Studies; Survival Rate; Treatment Outcome; X-Rays | 2008 |
Gastric phenotype signet-ring cell carcinoma of the stomach with multiple bone metastases effectively treated with sequential methotrexate and 5-fluorouracil.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Signet Ring Cell; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Stomach Neoplasms | 2008 |
Anthracyclines: the first generation of cytotoxic targeted agents? A possible dream.
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Epirubicin; ErbB Receptors; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Patient Selection; Receptor Protein-Tyrosine Kinases; Receptor, ErbB-2; Receptor, ErbB-3; Receptor, ErbB-4; Survival Analysis; Time Factors; Treatment Outcome | 2008 |
A novel assay to assess the effectiveness of antiangiogenic drugs in human breast cancer.
Topics: Angiogenesis Inhibitors; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Biological Assay; Blood Coagulation; Breast Neoplasms; Doxorubicin; Drug Screening Assays, Antitumor; Female; Fibrin; Fluorouracil; Humans; Methotrexate; Neoplasm Invasiveness; Neovascularization, Pathologic; Paclitaxel; Thrombin; Vincristine | 2008 |
A novel electrophysiological model of chemotherapy-induced cognitive impairments in mice.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Auditory Perception; Cognition Disorders; Electroencephalography; Electrophysiology; Evoked Potentials; Evoked Potentials, Auditory; Fear; Fluorouracil; Male; Methotrexate; Mice; Mice, Inbred C57BL; Neurotoxicity Syndromes; Recognition, Psychology | 2008 |
Expression profiling identifies genes that predict recurrence of breast cancer after adjuvant CMF-based chemotherapy.
Topics: Adaptor Proteins, Vesicular Transport; Adult; Aged; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Chemokine CXCL9; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Follow-Up Studies; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; GTP-Binding Protein alpha Subunit, Gi2; Histones; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mastectomy; Methotrexate; Middle Aged; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Recurrence; RNA, Messenger; RNA, Neoplasm | 2009 |
[A case of gastric cancer accompanied by disseminated carcinomatosis of bone marrow with DIC recovered by sequential therapy consisting of MTX and 5-FU].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow Neoplasms; Carcinoembryonic Antigen; Carcinoma; Disseminated Intravascular Coagulation; Fluorouracil; Humans; Male; Methotrexate; Stomach Neoplasms | 2008 |
Special focus on cardiac toxicity of different sequences of adjuvant doxorubicin/docetaxel/CMF regimens combined with radiotherapy in breast cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chi-Square Distribution; Combined Modality Therapy; Cyclophosphamide; Docetaxel; Doxorubicin; Female; Fluorouracil; Heart Diseases; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Pilot Projects; Prospective Studies; Radiotherapy Dosage; Taxoids; Treatment Outcome | 2009 |
Sentinel lymph node biopsy after preoperative chemotherapy for breast cancer: findings from the Austrian Sentinel Node Study Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Austria; Breast Neoplasms; Cyclophosphamide; Docetaxel; Doxorubicin; Female; Fluorouracil; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoadjuvant Therapy; Preoperative Care; Retrospective Studies; Sensitivity and Specificity; Sentinel Lymph Node Biopsy; Taxoids | 2008 |
The efficacy and safety of concurrent chemoradiotherapy for maxillary sinus squamous cell carcinoma patients.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Maxillary Sinus; Methotrexate; Middle Aged; Neoadjuvant Therapy; Organ Preservation; Paranasal Sinus Neoplasms; Retrospective Studies; Tegafur; Treatment Outcome; Uracil | 2009 |
[Study on adjuvant MTX-5-FU intraperitoneal chemotherapy for advanced gastric cancer].
Topics: Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Infusions, Parenteral; Male; Methotrexate; Neoplasm Staging; Stomach Neoplasms; Survival Rate | 2008 |
[Evaluation of 5-fluorouracil-related genes in breast cancer to predict the effect of adjuvant therapy with CMF].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Hormone Replacement Therapy; Humans; Methotrexate; Middle Aged; RNA, Messenger; Treatment Outcome | 2009 |
The prognostic impact of occult nodal metastasis in early breast carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Axilla; Bone Marrow; Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Norway; Prognosis; Tamoxifen | 2009 |
[A case of bone marrow carcinosis from gastric cancer that presented hypocalcemia caused by zoledronic acid during the treatment of methotrexate/5-fluorouracil sequential therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow; Calcinosis; Diphosphonates; Fatal Outcome; Fluorouracil; Gastroscopy; Humans; Hypocalcemia; Imidazoles; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Stomach Neoplasms; Tomography, X-Ray Computed; Zoledronic Acid | 2009 |
TLE3 as a candidate biomarker of response to taxane therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cohort Studies; Cyclophosphamide; Female; Fluorouracil; Humans; Immunoenzyme Techniques; Methotrexate; Middle Aged; Nuclear Proteins; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Repressor Proteins; Tissue Array Analysis | 2009 |
Quantitative phosphorus metabolomics using nanoflow liquid chromatography-tandem mass spectrometry and culture-derived comprehensive global internal standards.
Topics: Cell Line, Tumor; Chromatography, Liquid; Deoxycytidine; Fluorouracil; Gemcitabine; Humans; Metabolomics; Methotrexate; Phosphorus; Reference Standards; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2009 |
Concurrent chemoradiotherapy in adjuvant treatment of breast cancer.
Topics: Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Retrospective Studies | 2009 |
Protective effects of amifostine and cyclooxygenase-1 inhibitor against normal human epidermal keratinocyte toxicity induced by methotrexate and 5-fluorouracil.
Topics: Allopurinol; Amifostine; Antimetabolites, Antineoplastic; Calcium; Cell Line; Cell Proliferation; Cell Survival; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Interactions; Fibroblasts; Fluorouracil; Free Radical Scavengers; Glutamine; Humans; Keratinocytes; Methotrexate; Periodontal Ligament; Protective Agents; Pyrazoles; Reactive Oxygen Species; Stomatitis | 2009 |
Benefit of radiation boost after whole-breast radiotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Proportional Hazards Models; Radiotherapy Dosage; Radiotherapy, Adjuvant; Retreatment; Retrospective Studies | 2009 |
A new generalization of Weibull distribution with application to a breast cancer data set.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biometry; Breast Neoplasms; Cisplatin; Databases, Factual; Disease-Free Survival; Estrogen Receptor Modulators; Female; Fluorouracil; Humans; Likelihood Functions; Methotrexate; Models, Statistical; Proportional Hazards Models; Randomized Controlled Trials as Topic; Risk Factors; Survival Analysis; Tamoxifen; United States | 2009 |
Surgical resection in the management of pulmonary metastatic disease of gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dactinomycin; Drug Resistance, Neoplasm; Etoposide; Female; Fluorouracil; Gestational Trophoblastic Disease; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Vincristine; Young Adult | 2009 |
High prevalence of retinoblastoma protein loss in triple-negative breast cancers and its association with a good prognosis in patients treated with adjuvant chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Methotrexate; Middle Aged; Neoplasm Staging; Prevalence; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Retinoblastoma Protein | 2009 |
The acute effects of CMF-based chemotherapy on maxillary periodontal microcirculation.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Female; Fluorouracil; Gingiva; Image Processing, Computer-Assisted; Maxilla; Methotrexate; Microcirculation; Microscopy, Video; Periodontium; Rabbits; ROC Curve | 2009 |
Tissue inhibitor metalloproteinase type-1 (TIMP-1), a novel cancer biomarker predicting response of adjuvant anthracycline-based chemotherapy in patients afflicted with primary breast cancer.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Peptide Hydrolases; Tissue Inhibitor of Metalloproteinase-1 | 2009 |
Growth fraction as a predictor of response to chemotherapy in node-negative breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Immunoenzyme Techniques; Ki-67 Antigen; Lymph Nodes; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Prognosis; Survival Rate; Treatment Outcome | 2010 |
Intra-arterial infusion of chemotherapy in the treatment of penile cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Cisplatin; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Mitomycin; Penile Neoplasms; Remission Induction | 2009 |
Sequential chemotherapy with methotrexate and 5-fluorouracil for chemotherapy-naive advanced gastric cancer with disseminated intravascular coagulation at initial diagnosis.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Disseminated Intravascular Coagulation; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Retrospective Studies; Stomach Neoplasms; Survival Analysis; Treatment Failure; Treatment Outcome | 2010 |
Metastatic breast cancer survival according to HER2 and Topo2a gene status.
Topics: Adult; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cyclophosphamide; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Receptor, ErbB-2; Survival | 2009 |
Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells.
Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, p53; HCT116 Cells; Humans; Methotrexate; MicroRNAs; Osteosarcoma; Transfection; Tumor Cells, Cultured; Up-Regulation | 2009 |
Tumor tissue levels of Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) and outcome following adjuvant chemotherapy in premenopausal lymph node-positive breast cancer patients: A retrospective study.
Topics: Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Cyclophosphamide; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Premenopause; Retrospective Studies; Tissue Inhibitor of Metalloproteinase-1; Treatment Outcome | 2009 |
Variations in the content of CD34+ cells in the peripheral blood of cancer patients receiving out-patient chemotherapy.
Topics: Adolescent; Adult; Aged; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukocyte Count; Leukocytes; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasms; Outpatients; Prostatic Neoplasms; Young Adult | 1999 |
[Chemotherapy with MTX, 5-FU and CDGP for treatment of newly diagnosed head and neck cancer].
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds | 2009 |
Case series of multiple recurrent reactive keratoacanthomas developing at surgical margins.
Topics: Acitretin; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Fluorouracil; Forearm; Humans; Injections, Intralesional; Keratoacanthoma; Keratolytic Agents; Male; Methotrexate; Recurrence; Skin Neoplasms | 2009 |
Chemotherapy: Adjuvant chemotherapy in older patients with breast cancer.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Chemotherapy, Adjuvant; Cyclophosphamide; Deoxycytidine; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Drug Therapy; Female; Fluorouracil; Humans; Meta-Analysis as Topic; Methotrexate; Neoplasm Recurrence, Local; Neutropenia; Patient Compliance; Prospective Studies; Randomized Controlled Trials as Topic; Receptors, Estrogen; Survival Analysis; Therapeutic Equivalency | 2009 |
Information technology facilitates cost-effectiveness analysis in developing countries: an observational study of breast cancer chemotherapy in Taiwan.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Breast Neoplasms; Cost-Benefit Analysis; Cyclophosphamide; Cytarabine; Developing Countries; Economics, Pharmaceutical; Epirubicin; Female; Fluorouracil; Health Care Costs; Humans; Information Systems; Insurance Claim Reporting; Methotrexate; Models, Economic; National Health Programs; Policy Making; Taiwan | 2009 |
Efficacy of sequential methotrexate and 5-fluorouracil (MTX/5FU) in improving oral intake in patients with advanced gastric cancer with severe peritoneal dissemination.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascites; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Peritoneal Neoplasms; Quality of Life; Retrospective Studies; Severity of Illness Index; Stomach Neoplasms; Survival Rate; Treatment Outcome | 2009 |
Gallbladder squamous cell carcinoma in the setting of low-dose methotrexate use.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cholecystectomy, Laparoscopic; Cisplatin; Dermatologic Agents; Dose-Response Relationship, Drug; Fatal Outcome; Female; Fluorouracil; Gallbladder Neoplasms; Gallstones; Humans; Incidental Findings; Liver Neoplasms; Methotrexate; Neoplasm Seeding; Peritoneal Neoplasms; Psoriasis | 2009 |
Doxorubicin and cyclophosphamide versus cyclophosphamide, methotrexate, and 5-fluorouracil as adjuvant chemotherapy in breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Rate; Treatment Outcome | 2009 |
Pathologic complete response rates in young women with BRCA1-positive breast cancers after neoadjuvant chemotherapy.
Topics: Adult; Age Factors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Docetaxel; Doxorubicin; Female; Fluorouracil; Genes, BRCA1; Humans; Methotrexate; Middle Aged; Neoadjuvant Therapy; Registries; Taxoids | 2010 |
Serum factors that suppress cytotoxic effect of methotrexate.
Topics: Animals; Antimetabolites, Antineoplastic; Azaserine; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Culture Media; Culture Media, Serum-Free; Electrophoresis, Gel, Two-Dimensional; Fluorouracil; Humans; Mass Spectrometry; Methotrexate; Serum; Serum Albumin | 2009 |
Re: International guidelines for management of metastatic breast cancer: combination vs sequential single-agent chemotherapy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; International Cooperation; Methotrexate; Practice Guidelines as Topic; Prednisone; Randomized Controlled Trials as Topic | 2010 |
[Clinical impact of extracapsular extension of axillary lymph node metastases in breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Mastectomy; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Postmenopause; Proportional Hazards Models; Retrospective Studies; Risk Factors; Survival Rate | 2009 |
High levels of uPA and PAI-1 predict a good response to anthracyclines.
Topics: Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Multivariate Analysis; Plasminogen Activator Inhibitor 1; Predictive Value of Tests; Proportional Hazards Models; Retrospective Studies; Survival Analysis; Urokinase-Type Plasminogen Activator | 2010 |
Rho GDP dissociation inhibitor alpha expression correlates with the outcome of CMF treatment in invasive ductal breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Cisplatin; Drug Resistance, Neoplasm; Female; Fluorouracil; Guanine Nucleotide Dissociation Inhibitors; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Methotrexate; Middle Aged; Neoplasm Staging; Reverse Transcriptase Polymerase Chain Reaction; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Risk Factors; Treatment Outcome | 2010 |
Antiproliferative effects of anastrozole, methotrexate, and 5-fluorouracil on endometriosis in vitro and in vivo.
Topics: Adult; Anastrozole; Animals; Antineoplastic Agents; Biopsy; Case-Control Studies; Cell Proliferation; Cell Survival; Cells, Cultured; Endometriosis; Endometrium; Female; Fluorouracil; Humans; Methotrexate; Mice; Mice, Nude; Nitriles; Progesterone; Transplantation, Heterologous; Triazoles; Uterine Diseases | 2010 |
[Complete response to M-FAP chemotherapy for multiple lung metastases after segmental resection of urachal carcinoma : a case report].
Topics: Adenocarcinoma; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Epirubicin; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Urachus; Urinary Bladder Neoplasms | 2010 |
[Role of adjuvant chemotherapy in the choice of chemotherapeutic treatment of metastatic breast cancer].
Topics: Anthracyclines; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Trastuzumab | 2009 |
Advanced penile verrucous carcinoma treated with intra-aortic infusion chemotherapy.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Aorta, Abdominal; Carcinoma, Verrucous; Fluorouracil; Humans; Infusions, Intra-Arterial; Leucovorin; Male; Methotrexate; Middle Aged; Mitomycin; Penile Neoplasms; Treatment Outcome; Vitamin B Complex | 2010 |
[A case of recurrent breast cancer with life-threatening liver metastasis remarkably responding to classical CMF].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate | 2010 |
[A case of multidrug-resistant breast cancer associated with multiple hepatic and bone metastases for which cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy proved effective].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Middle Aged | 2010 |
Autocrine induction of invasive and metastatic phenotypes by the MIF-CXCR4 axis in drug-resistant human colon cancer cells.
Topics: Animals; Colonic Neoplasms; Doxorubicin; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Profiling; Gene Silencing; HT29 Cells; Humans; Intramolecular Oxidoreductases; Macrophage Migration-Inhibitory Factors; Methotrexate; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Phenotype; Receptors, CXCR4; Signal Transduction; Up-Regulation | 2010 |
CEF is superior to CMF for tumours with TOP2A aberrations: a Subpopulation Treatment Effect Pattern Plot (STEPP) analysis on Danish Breast Cancer Cooperative Group Study 89D.
Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Data Interpretation, Statistical; Disease-Free Survival; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Neoplasm; Epirubicin; Female; Fluorouracil; Gene Dosage; Humans; In Situ Hybridization, Fluorescence; Methotrexate; Poly-ADP-Ribose Binding Proteins; Randomized Controlled Trials as Topic; Treatment Outcome | 2010 |
A mathematical model of breast cancer treatment with CMF and doxorubicin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Models, Biological | 2011 |
[Adjuvant chemotherapy in older women with breast cancer. CALGB Study (The Cancer and Leukemia Group B Study)].
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Deoxycytidine; Doxorubicin; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Male; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Receptors, Estrogen; Survival Analysis | 2010 |
The clinical outcome of chemotherapy-induced amenorrhea in premenopausal young patients with breast cancer with long-term follow-up.
Topics: Adult; Amenorrhea; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Premenopause; Survival Rate; Tamoxifen; Treatment Outcome | 2010 |
A breast cancer prognostic signature predicts clinical outcomes in multiple tumor types.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmacological; Biomarkers, Tumor; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Gene Expression Profiling; Humans; Lung Neoplasms; Methotrexate; Neoplasms; Prognosis; Survival Analysis; Tamoxifen; Treatment Outcome | 2010 |
Adjuvant radiotherapy and chemotherapy in breast cancer: 30 year follow-up of survival.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Survival Rate; Treatment Outcome | 2010 |
Neoadjuvant treatment in young women with breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Docetaxel; Doxorubicin; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Molecular Targeted Therapy; Neoadjuvant Therapy; Paclitaxel; Prognosis; Radiotherapy, Adjuvant; Sentinel Lymph Node Biopsy; Taxoids; Treatment Outcome | 2010 |
Adjuvant chemotherapy in young women with breast cancer.
Topics: Adult; Age Factors; Amenorrhea; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Genes, erbB-2; Humans; Methotrexate; Primary Ovarian Insufficiency; Risk Factors; SEER Program; Taxoids | 2010 |
Comparison of the multi-drug resistant human hepatocellular carcinoma cell line Bel-7402/ADM model established by three methods.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Glutathione; Glutathione Transferase; Humans; Inhibitory Concentration 50; Liver Neoplasms; Male; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Multidrug Resistance-Associated Proteins; Organoplatinum Compounds; Time Factors; Xenograft Model Antitumor Assays | 2010 |
Long-term survival of a patient with leptomeningeal involvement by nasopharyngeal carcinoma after treatment with high-dose intravenous methotrexate.
Topics: Adult; Antimetabolites, Antineoplastic; Cisplatin; Fluorouracil; Humans; Infusions, Intravenous; Magnetic Resonance Imaging; Male; Meningeal Carcinomatosis; Methotrexate; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Radiotherapy Dosage | 2012 |
Comparison of three adjuvant chemotherapy regimes using an extended log-logistic model in women with operable breast cancer.
Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Iran; Lymphatic Metastasis; Methotrexate; Middle Aged; Models, Statistical; Neoplasm Staging; Prognosis; Survival Rate; Taxoids | 2010 |
The incidence of symptomatic thromboembolism in patients receiving adjuvant anthracycline-based chemotherapy for early stage breast cancer.
Topics: Adult; Aged; Anthracyclines; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Breast Neoplasms, Male; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Incidence; Male; Methotrexate; Middle Aged; Neoplasm Staging; Retrospective Studies; Thromboembolism | 2011 |
[Practice and consideration on neoadjuvant therapy for early breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; Paclitaxel; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Tumor Burden | 2010 |
Taxane-based regimens as a risk factor for chemotherapy-induced amenorrhea.
Topics: Adult; Amenorrhea; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Risk Factors; Taxoids; Treatment Outcome | 2011 |
Effect of de novo purine synthesis inhibitors on 5-fluorouracil metabolism and cytotoxicity.
Topics: Alanine; Animals; Azaserine; Cell Line, Tumor; Cell Survival; Diazooxonorleucine; Dose-Response Relationship, Drug; Fluorouracil; Methotrexate; Nucleic Acid Synthesis Inhibitors; Purines; Thioinosine; Thionucleotides; Uracil Nucleotides | 1981 |
Validation of treatment efficacy of a computer-assisted program for breast cancer patients receiving postoperative adjuvant chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Docetaxel; Doxorubicin; Drug Therapy, Computer-Assisted; Epirubicin; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Methotrexate; Middle Aged; Paclitaxel; Survival Analysis; Taxoids | 2010 |
High estrogen receptor expression in early breast cancer: chemotherapy needed to improve RFS?
Topics: Adult; Aged; Anthracyclines; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cohort Studies; Disease-Free Survival; Early Detection of Cancer; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Methotrexate; Middle Aged; Proportional Hazards Models; Receptors, Estrogen; Taxoids; Treatment Outcome | 2011 |
Re: Topoisomerase II alpha and responsiveness of breast cancer to adjuvant chemotherapy.
Topics: Anthracyclines; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; DNA Topoisomerases, Type II; DNA-Binding Proteins; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Predictive Value of Tests; Prognosis; Treatment Outcome | 2011 |
Imaging colon cancer response following treatment with AZD1152: a preclinical analysis of [18F]fluoro-2-deoxyglucose and 3'-deoxy-3'-[18F]fluorothymidine imaging.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Dideoxynucleosides; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Fluorouracil; HCT116 Cells; Humans; Immunoblotting; Ki-67 Antigen; Methotrexate; Mice; Mice, Nude; Organophosphates; Positron-Emission Tomography; Quinazolines; Radiopharmaceuticals; Thymidine; Thymidine Kinase; Xenograft Model Antitumor Assays | 2011 |
Exclusive alternating chemotherapy and radiotherapy in nonmetastatic inflammatory breast cancer: 20 years of follow-up.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachial Plexus Neuropathies; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Combined Modality Therapy; Cyclophosphamide; Dose Fractionation, Radiation; Doxorubicin; Drug Administration Schedule; Epirubicin; Female; Fibrosis; Fluorouracil; Follow-Up Studies; Heart; Humans; Inflammatory Breast Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Radiation Injuries; Radiation Pneumonitis; Survival Rate; Tamoxifen; Time Factors; Vincristine | 2012 |
Breast cancer: adjuvant modalities.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Goserelin; Humans; Methotrexate; Ovary; Tamoxifen; Taxoids; Trastuzumab | 2011 |
Changes in pulmonary function up to 10 years after locoregional breast irradiation.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carbon Monoxide; Cyclophosphamide; Female; Fluorouracil; Forced Expiratory Volume; Humans; Lung; Methotrexate; Middle Aged; Pulmonary Diffusing Capacity; Radiation Pneumonitis; Recovery of Function; Respiratory Function Tests; Tamoxifen; Time Factors; Total Lung Capacity; Vital Capacity | 2012 |
Concomitant adjuvant chemo-radiation therapy with anthracycline-based regimens in breast cancer: a single centre experience.
Topics: Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Early Detection of Cancer; Epirubicin; Feasibility Studies; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Retrospective Studies; Risk Assessment; Risk Factors; Treatment Outcome | 2011 |
[Analysis of prophylactic chemotherapy outcome and clinical characteristics in patients of high-risk hydatidiform mole].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta Subunit, Human; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Methotrexate; Pregnancy; Retrospective Studies; Risk Factors; Treatment Outcome; Uterine Neoplasms | 2011 |
[Successful withdrawal from disseminated intravascular coagulation caused by disseminated carcinomatosis of bone marrow originated from gastric cancer treated by sequential therapy consisting of MTX and 5-FU and palliative radiotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Disseminated Intravascular Coagulation; Fatal Outcome; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Palliative Care; Stomach Neoplasms | 2011 |
APEX microarray panel for genotyping polymorphisms in cancer chemotherapy and estimation frequencies in a Slovak population.
Topics: Antineoplastic Agents; Biomarkers, Pharmacological; Camptothecin; Drug Resistance, Neoplasm; Fluorouracil; Gene Frequency; Genetic Association Studies; Humans; Irinotecan; Linkage Disequilibrium; Methotrexate; Neoplasms; Oligonucleotide Array Sequence Analysis; Polymorphism, Single Nucleotide; Slovakia | 2011 |
Classical CMF regimen as adjuvant chemotherapy for triple-negative breast cancer may be more effective compared with anthracycline or taxane-based regimens.
Topics: Adolescent; Adult; Aged; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Immunoenzyme Techniques; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Survival Rate; Taxoids; Young Adult | 2012 |
Effects of repeated administration of chemotherapeutic agents tamoxifen, methotrexate, and 5-fluorouracil on the acquisition and retention of a learned response in mice.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Behavior, Animal; Body Weight; Conditioning, Operant; Dose-Response Relationship, Drug; Fluorouracil; Learning; Male; Memory; Methotrexate; Mice; Mice, Inbred Strains; Selective Estrogen Receptor Modulators; Tamoxifen | 2011 |
Disseminated intravascular coagulation as the presenting sign of gastric cancer during pregnancy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Carcinoma, Signet Ring Cell; Disseminated Intravascular Coagulation; Female; Fluorouracil; Humans; Methotrexate; Pregnancy; Pregnancy Complications, Neoplastic; Stomach Neoplasms | 2011 |
[A case of gastric cancer accompanied by disseminated carcinomatosis of bone marrow with DIC, and subdural hematoma successfully treated with sequential methotrexate and 5-fluorouracil therapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Disseminated Intravascular Coagulation; Fluorouracil; Hematoma, Subdural; Humans; Male; Methotrexate; Stomach Neoplasms | 2011 |
The cost-effectiveness of adjuvant chemotherapy for early breast cancer: A comparison of no chemotherapy and first, second, and third generation regimens for patients with differing prognoses.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Cyclophosphamide; Docetaxel; Epirubicin; Female; Fluorouracil; Health Care Costs; Humans; Methotrexate; Middle Aged; Prognosis; Quality-Adjusted Life Years; Taxoids | 2011 |
Incidental findings on brain Magnetic Resonance Imaging in long-term survivors of breast cancer treated with adjuvant chemotherapy.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Incidence; Incidental Findings; Intracranial Aneurysm; Magnetic Resonance Imaging; Meningioma; Methotrexate; Middle Aged; Neoplasms, Second Primary; Pituitary Neoplasms; Survivors | 2011 |
Does the addition of chemotherapy to adjuvant endocrine treatment add any benefit in ER-positive early breast cancer: can we rely on large randomized control trials in the era of personalized medicine?
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Estrogen Receptor Modulators; Female; Fluorouracil; Humans; Methotrexate; Precision Medicine; Randomized Controlled Trials as Topic; Receptors, Estrogen | 2011 |
Donepezil reduces cognitive impairment associated with anti-cancer drugs in a mouse model.
Topics: Analysis of Variance; Animals; Antineoplastic Combined Chemotherapy Protocols; Cognition Disorders; Cues; Disease Models, Animal; Donepezil; Female; Fluorouracil; Indans; Maze Learning; Memory; Methotrexate; Mice; Mice, Inbred BALB C; Nootropic Agents; Piperidines; Space Perception; Time Factors | 2011 |
Premature ovarian failure and body composition changes with adjuvant chemotherapy for breast cancer.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Composition; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Premenopause; Primary Ovarian Insufficiency; Prospective Studies; Tamoxifen; Weight Gain | 2011 |
Promising long-term results with attenuated adverse effects by methotrexate-containing sequential chemoradiation therapy in locally advanced head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Quality of Life; Radiotherapy; Remission Induction; Retrospective Studies; Survival Analysis | 2011 |
Inhibition of EGFR phosphorylation in a panel of human breast cancer cells correlates with synergistic interactions between gefitinib and 5'-DFUR, the bioactive metabolite of Xeloda.
Topics: Antineoplastic Agents; Breast Neoplasms; Capecitabine; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxycytidine; Drug Synergism; ErbB Receptors; Female; Floxuridine; Fluorouracil; Gefitinib; Gene Expression Regulation, Enzymologic; Humans; Inhibitory Concentration 50; Methotrexate; Phosphorylation; Protein Processing, Post-Translational; Quinazolines; Thymidine Phosphorylase; Thymidylate Synthase | 2012 |
Prognostic significance of UBE2C mRNA expression in high-risk early breast cancer. A Hellenic Cooperative Oncology Group (HeCOG) Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Staging; Paclitaxel; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Retrospective Studies; RNA, Messenger; Transcription, Genetic; Tumor Burden; Ubiquitin-Conjugating Enzymes; Young Adult | 2012 |
C-myc as a predictive marker for chemotherapy in metastatic breast cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Proto-Oncogene Proteins c-myc; Survival Analysis; Tamoxifen; Treatment Outcome | 2012 |
Calling attention to radiation recall reactions. Simultaneous occurrence of a Recall Dermatitis after CMF application in two separate sites irradiated 10 years apart.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dermatitis; Drug Eruptions; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Radiodermatitis; Radiotherapy; Time Factors | 2012 |
Utilization of fluorescence in situ hybridization with cytokeratin discriminators in TOP2A assessment of chemotherapy-treated patients with breast cancer.
Topics: Adult; Aged; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; DNA Topoisomerases, Type II; DNA-Binding Proteins; Female; Fluorouracil; Humans; In Situ Hybridization, Fluorescence; Keratins; Methotrexate; Middle Aged; Poly-ADP-Ribose Binding Proteins; Tissue Array Analysis; Treatment Outcome | 2012 |
Comparison of concurrent chemoradiotherapy versus induction chemotherapy followed by radiation in patients with nasopharyngeal carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemoradiotherapy; Chemotherapy, Adjuvant; Cisplatin; Docetaxel; Female; Fluorouracil; Humans; Induction Chemotherapy; Leucovorin; Male; Methotrexate; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoadjuvant Therapy; Retrospective Studies; Taxoids | 2012 |
Multilevel latent variable models for global health-related quality of life assessment.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Cyclophosphamide; Deoxycytidine; Female; Fluorouracil; Humans; Methotrexate; Models, Psychological; Models, Statistical; Quality of Life; Randomized Controlled Trials as Topic; Surveys and Questionnaires | 2012 |
Efficacy of the CMFVP regimen in patients with metastatic breast cancer previously treated with anthracycline and taxane.
Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Carcinoma; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Prednisone; Taxoids; Treatment Outcome; Vincristine | 2012 |
Loss of E-cadherin promotes the growth, invasion and drug resistance of colorectal cancer cells and is associated with liver metastasis.
Topics: Active Transport, Cell Nucleus; Antimetabolites, Antineoplastic; beta Catenin; Cadherins; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Fluorouracil; Gene Knockdown Techniques; HCT116 Cells; HT29 Cells; Humans; Liver Neoplasms; Methotrexate; Neoplasm Invasiveness; Transcription, Genetic | 2012 |
Clinical correlates of 'BRCAness' in triple-negative breast cancer of patients receiving adjuvant chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BRCA1 Protein; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Docetaxel; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Proportional Hazards Models; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Taxoids; Treatment Outcome; Young Adult | 2012 |
Neuropsychological performance in survivors of breast cancer more than 20 years after adjuvant chemotherapy.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cognition; Cohort Studies; Cyclophosphamide; Executive Function; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neuropsychological Tests; Psychomotor Performance; Survivors; Time Factors | 2012 |
Resumption or persistence of menstruation after cytotoxic chemotherapy is a prognostic factor for poor disease-free survival in premenopausal patients with early breast cancer.
Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Cyclophosphamide; Deoxycytidine; Disease-Free Survival; Docetaxel; Doxorubicin; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Menstrual Cycle; Methotrexate; Middle Aged; Multivariate Analysis; Premenopause; Prognosis; Proportional Hazards Models; Retrospective Studies; Taxoids; Young Adult | 2012 |
The effects of chemotherapy on cognitive function in a mouse model: a prospective study.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cognition; Disease Models, Animal; Female; Fluorouracil; Learning; Longitudinal Studies; Memory; Methotrexate; Mice; Mice, Inbred BALB C; Neuropsychological Tests; Prospective Studies; Time Factors | 2012 |
A population-based study on the patterns of use of different chemotherapy regimens in Swiss patients with early breast cancer.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Capecitabine; Carboplatin; Confidence Intervals; Cyclophosphamide; Deoxycytidine; Doxorubicin; Epirubicin; Female; Fluorouracil; Gemcitabine; Health Services Accessibility; Humans; Logistic Models; Lymphatic Metastasis; Medication Adherence; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Staging; Odds Ratio; Paclitaxel; Receptors, Estrogen; Switzerland; Taxoids; Vinblastine; Vinorelbine | 2012 |
Blockade of interleukin-6 receptor suppresses the proliferation of H460 lung cancer stem cells.
Topics: Antibodies, Neutralizing; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Fluorouracil; Gene Expression; Gene Knockdown Techniques; Homeodomain Proteins; Humans; Interleukin-6; Lung Neoplasms; Methotrexate; Nanog Homeobox Protein; Neoplastic Stem Cells; Receptors, Interleukin-6; RNA Interference; Signal Transduction; Spheroids, Cellular; Up-Regulation | 2012 |
Improved outcome of high-risk early HER2 positive breast cancer with high CXCL13-CXCR5 messenger RNA expression.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Carcinoma; Chemokine CXCL13; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Middle Aged; Multicenter Studies as Topic; Prognosis; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Receptors, CXCR5; Retrospective Studies; Risk; RNA, Messenger; Treatment Outcome; Up-Regulation; Young Adult | 2012 |
DNA synthesis as a therapeutic target: the first 65 years.
Topics: Aminopterin; Antimetabolites, Antineoplastic; DNA Replication; Fluorouracil; Folic Acid; Folic Acid Antagonists; History, 20th Century; Humans; Hydroxyurea; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrahydrofolate Dehydrogenase | 2012 |
Differential response of immunohistochemically defined breast cancer subtypes to anthracycline-based adjuvant chemotherapy with or without paclitaxel.
Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Epirubicin; ErbB Receptors; Female; Fluorouracil; Humans; Immunohistochemistry; Keratin-5; Methotrexate; Middle Aged; Paclitaxel; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Young Adult | 2012 |
Mesenchymal stem cells derived from different origins have unique sensitivities to different chemotherapeutic agents.
Topics: Adipose Tissue; Animals; Antineoplastic Agents; Apoptosis; Bone Marrow Cells; Busulfan; Cell Proliferation; Cell Survival; Cellular Senescence; Doxorubicin; Fluorouracil; Gene Expression; Gene Expression Regulation; Mesenchymal Stem Cells; Methotrexate; Rats; Rats, Sprague-Dawley | 2012 |
A risk score based on histopathological features predicts higher risk of distant recurrence in premenopausal patients with lymph node-negative endocrine-responsive breast cancer.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Decision Support Techniques; Female; Fluorouracil; Goserelin; Humans; Ki-67 Antigen; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Invasiveness; Neoplasm Metastasis; Nomograms; Premenopause; Randomized Controlled Trials as Topic; Receptors, Estrogen; Risk Assessment; Survival Analysis; Tamoxifen; Treatment Outcome; Tumor Burden | 2012 |
Relationship between antimetabolite toxicity and pharmacogenetics in Turkish cancer patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Alleles; Antimetabolites, Antineoplastic; Bone Neoplasms; Breast Neoplasms; Capecitabine; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); DNA; DNA-Binding Proteins; Drug Eruptions; Female; Fluorouracil; Gastrointestinal Neoplasms; Gene Frequency; Humans; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Minisatellite Repeats; Mucositis; Osteosarcoma; Polymorphism, Genetic; Thymidylate Synthase; Turkey; X-ray Repair Cross Complementing Protein 1; Xeroderma Pigmentosum Group D Protein; Young Adult | 2012 |
A thymidylate synthase ternary complex-specific antibody, FTS, permits functional monitoring of fluoropyrimidines dosing.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Monitoring; Female; Floxuridine; Fluorouracil; Immunoenzyme Techniques; Methotrexate; Mice; Mice, Nude; Pancreatic Neoplasms; Rats; Thymidylate Synthase; Transplantation, Heterologous; Tumor Cells, Cultured | 2012 |
Clinicopathological significance of mesothelin expression in invasive breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; GPI-Linked Proteins; Humans; Immunohistochemistry; Lymphatic Metastasis; Mesothelin; Methotrexate; Neoplasm Invasiveness; Paraffin Embedding; Radiotherapy; Receptor, ErbB-3; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies | 2012 |
Long-term heart function after adjuvant epirubicin chemotherapy for breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Breast Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Cyclophosphamide; Denmark; Drug Administration Schedule; Echocardiography; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Heart; Heart Failure; Humans; Methotrexate; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Radionuclide Ventriculography; Registries; Stroke Volume; Time Factors | 2012 |
Long-term biomonitoring of breast cancer patients under adjuvant chemotherapy: the comet assay as a possible predictive factor.
Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Comet Assay; Cyclophosphamide; DNA Damage; Epirubicin; Female; Fluorouracil; Glutathione Transferase; Humans; Methotrexate; Middle Aged; Predictive Value of Tests; Principal Component Analysis; Treatment Outcome | 2013 |
Association of the Arg194Trp and the Arg399Gln polymorphisms of the XRCC1 gene with risk occurrence and the response to adjuvant therapy among Polish women with breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; DNA Repair; DNA-Binding Proteins; Doxorubicin; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Humans; Immunoenzyme Techniques; Methotrexate; Neoplasm Invasiveness; Neoplasm Staging; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Risk Factors; Survival Rate; X-ray Repair Cross Complementing Protein 1 | 2013 |
Does immediate breast reconstruction compromise the delivery of adjuvant chemotherapy?
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Incidence; Kaplan-Meier Estimate; Logistic Models; Mammaplasty; Mastectomy; Methotrexate; Middle Aged; Multivariate Analysis; Postoperative Complications; Retrospective Studies; Taxoids; Time Factors; Treatment Outcome | 2013 |
Influence of anticancer agents on cell survival, proliferation, and CD4+CD25+Foxp3+ regulatory T cell-frequency in human peripheral-blood mononuclear cells activated by T cell-mitogen.
Topics: Adolescent; Adult; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Proliferation; Cell Survival; Concanavalin A; Cytokines; Dacarbazine; Female; Fluorouracil; Humans; Immunosuppressive Agents; Leukocytes, Mononuclear; Male; Methotrexate; Mitogens; Oxides; T-Lymphocytes, Regulatory; Young Adult | 2013 |
Global and focal white matter integrity in breast cancer survivors 20 years after adjuvant chemotherapy.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain; Breast Neoplasms; Chemotherapy, Adjuvant; Cross-Sectional Studies; Cyclophosphamide; Diffusion Tensor Imaging; Female; Fluorouracil; Humans; Leukoencephalopathies; Methotrexate; Middle Aged; Survivors; Time Factors | 2014 |
Is there an association between PONV and chemotherapy-induced nausea and vomiting?
Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Betamethasone; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease Resistance; Droperidol; Epirubicin; Female; Fluorouracil; Granisetron; Humans; Mastectomy; Methotrexate; Metoclopramide; Middle Aged; Models, Biological; Narcotics; Nausea; Ondansetron; Postoperative Nausea and Vomiting; Prospective Studies; Risk Factors; Vomiting | 2013 |
Concurrent chemotherapy inhibits herpes simplex virus-1 replication and oncolysis.
Topics: Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Herpesvirus 1, Human; Humans; Irinotecan; Methotrexate; NF-kappa B; Oncolytic Virotherapy; Oncolytic Viruses; Pancreatic Neoplasms; Transcriptional Activation; Tumor Necrosis Factor-alpha; Virus Replication | 2013 |
Tumor STAT3 tyrosine phosphorylation status, as a predictor of benefit from adjuvant chemotherapy for breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Methotrexate; Middle Aged; Multivariate Analysis; Phosphorylation; Proportional Hazards Models; Protein Processing, Post-Translational; STAT3 Transcription Factor; Treatment Outcome; Tyrosine | 2013 |
Pharmacokinetic application of a bio-analytical LC-MS method developed for 5-fluorouracil and methotrexate in mouse plasma, brain and urine.
Topics: Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Drug Stability; Fluorouracil; Linear Models; Male; Mass Spectrometry; Methotrexate; Mice; Reproducibility of Results; Sensitivity and Specificity | 2013 |
Breast-conserving surgery after tumor downstaging by neoadjuvant chemotherapy is oncologically safe for stage III breast cancer patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Docetaxel; Doxorubicin; Female; Fluorouracil; Humans; Ki-67 Antigen; Lymphatic Metastasis; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Paclitaxel; Radiotherapy, Adjuvant; Retrospective Studies; Risk Factors; Survival Rate; Taxoids | 2013 |
New advances in the treatment of gastric cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Cisplatin; Deoxycytidine; Docetaxel; Doxorubicin; Drug Combinations; Etoposide; Fluorouracil; Humans; Leucovorin; Levoleucovorin; Methotrexate; Organoplatinum Compounds; Oxonic Acid; Stomach Neoplasms; Taxoids; Tegafur | 2004 |
CMF-regimen preferred as first-course chemotherapy for older and sicker women with breast cancer: Findings from a SEER-Medicare-based population study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Female; Fluorouracil; Humans; Medicare; Methotrexate; Practice Patterns, Physicians'; SEER Program; United States | 2015 |
[Approximately four years of survival benefits for a case of gastric cancer postoperative carcinomatous peritonitis by combined modality therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Combined Modality Therapy; Drug Combinations; Fatal Outcome; Female; Fluorouracil; Gastrectomy; Humans; Irinotecan; Methotrexate; Middle Aged; Oxonic Acid; Paclitaxel; Peritoneal Neoplasms; Peritonitis; Stomach Neoplasms; Tegafur; Time Factors | 2013 |
Dysregulation in myelination mediated by persistent neuroinflammation: possible mechanisms in chemotherapy-related cognitive impairment.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cognition Disorders; Corpus Callosum; Cyclophosphamide; Cytokines; Female; Fluorouracil; Inflammation; Methotrexate; Nerve Fibers, Myelinated; Random Allocation; Rats; Rats, Sprague-Dawley; Recognition, Psychology | 2014 |
Letrozole combined with gonadotropin-releasing hormone analog for metastatic male breast cancer.
Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms, Male; Carcinoma, Ductal, Breast; Carcinoma, Papillary; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Docetaxel; Epirubicin; Estrogen Receptor Modulators; Estrogens; Fluorouracil; Gonadotropin-Releasing Hormone; Goserelin; Humans; Kaplan-Meier Estimate; Letrozole; Male; Mastectomy, Modified Radical; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Progesterone; Radiotherapy, Adjuvant; Tamoxifen; Taxoids; Triazoles | 2013 |
Significance of GATA-3 expression in outcomes of patients with breast cancer who received systemic chemotherapy and/or hormonal therapy and clinicopathologic features of GATA-3-positive tumors.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; GATA3 Transcription Factor; Humans; Methotrexate; Middle Aged; Minnesota; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Tissue Array Analysis; Treatment Outcome | 2013 |
Prognostic factors of metastatic or recurrent esophageal squamous cell carcinoma in patients receiving three-drug combination chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Docetaxel; Esophageal Neoplasms; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Paclitaxel; Prognosis; Recurrence; Survival Analysis; Taxoids | 2013 |
γ-Glutamyl hydrolase modulation and folate influence chemosensitivity of cancer cells to 5-fluorouracil and methotrexate.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Drug Screening Assays, Antitumor; Female; Fluorouracil; Folic Acid; gamma-Glutamyl Hydrolase; HCT116 Cells; Humans; Male; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; RNA, Small Interfering; Transfection; Xenograft Model Antitumor Assays | 2013 |
Patterns of failure after radiosurgery to two different target volumes of enhancing lesions with and without FLAIR abnormalities in recurrent glioblastoma multiforme.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Glioblastoma; Humans; Leucovorin; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Postoperative Complications; Radiosurgery; Retrospective Studies; Treatment Outcome | 2014 |
Carcinoembryonic antigen expression level as a predictive factor for response to 5-fluorouracil in colorectal cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoembryonic Antigen; Cell Line, Tumor; CHO Cells; Cisplatin; Colorectal Neoplasms; Cricetinae; Cricetulus; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fluorouracil; Gene Expression; Humans; Inhibitory Concentration 50; Methotrexate; Spheroids, Cellular | 2014 |
Physical exercise prevents suppression of hippocampal neurogenesis and reduces cognitive impairment in chemotherapy-treated rats.
Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Cognition Disorders; Cues; Dentate Gyrus; Doublecortin Domain Proteins; Doublecortin Protein; Female; Fluorouracil; Housing, Animal; Immunohistochemistry; Learning; Memory; Methotrexate; Microtubule-Associated Proteins; Motor Activity; Neurogenesis; Neuropeptides; Neuropsychological Tests; Rats, Long-Evans; Spatial Memory | 2014 |
Weight change trajectory in women with breast cancer receiving chemotherapy and the effect of different regimens.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Longitudinal Studies; Menopause; Methotrexate; Middle Aged; Weight Gain | 2014 |
Failure and success in the treatment of breast carcinoma in men: a case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Back Pain; Breast Neoplasms, Male; Carcinoma, Ductal, Breast; Cyclophosphamide; Doxorubicin; Fluorouracil; Fractures, Compression; Humans; Kyphoplasty; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Staging; Spinal Fractures; Spinal Neoplasms; Stents; Tamoxifen; Thoracic Vertebrae; Tomography, X-Ray Computed; Treatment Outcome; Vertebroplasty | 2014 |
[Clinicopathologic characteristics of primary breast leiomyosarcoma: report of a case].
Topics: Actins; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Calcium-Binding Proteins; Calponins; Carcinoma; Cyclophosphamide; Desmin; Diagnosis, Differential; Female; Fibrosarcoma; Fluorouracil; Follow-Up Studies; Humans; Leiomyosarcoma; Mastectomy, Segmental; Methotrexate; Microfilament Proteins; Neurilemmoma; Phyllodes Tumor; Postoperative Period; Vimentin | 2013 |
Aberrant DNA methylation status of DNA repair genes in breast cancer treated with neoadjuvant chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; CpG Islands; Cyclophosphamide; DNA Methylation; DNA Repair; Docetaxel; Female; Fluorouracil; Homologous Recombination; Humans; Methotrexate; Middle Aged; Neoadjuvant Therapy; Taxoids; Triple Negative Breast Neoplasms | 2013 |
Quantitative analysis of the anti-proliferative activity of combinations of selected iron-chelating agents and clinically used anti-neoplastic drugs.
Topics: Aldehydes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Cyclophosphamide; Deferoxamine; Doxorubicin; Drug Synergism; Fluorouracil; Humans; Hydrazones; Iron Chelating Agents; MCF-7 Cells; Methotrexate; Paclitaxel; Tamoxifen; Thiosemicarbazones | 2014 |
Identification of patients with node-negative, triple-negative breast cancer who benefit from adjuvant cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Grading; Neoplasm Recurrence, Local; Prognosis; Retrospective Studies; Survival Rate; Triple Negative Breast Neoplasms | 2014 |
microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cyclophosphamide; Docetaxel; Down-Regulation; Doxorubicin; Epirubicin; ErbB Receptors; Female; Fluorouracil; Gene Expression Profiling; Humans; Kaplan-Meier Estimate; Keratin-5; Keratin-6; Methotrexate; MicroRNAs; Middle Aged; Oligonucleotide Array Sequence Analysis; Paclitaxel; Prognosis; Risk Assessment; Survival Rate; Taxoids; Triple Negative Breast Neoplasms; Up-Regulation | 2014 |
Enzymatic and structural characterization of rTSγ provides insights into the function of rTSβ.
Topics: Crystallography, X-Ray; Fluorouracil; Humans; Hydro-Lyases; Isoenzymes; Methotrexate; Models, Molecular; Protein Conformation | 2014 |
Apoptotic enteropathy caused by antimetabolites and TNF-α antagonists.
Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Apoptosis; Biopsy; Capecitabine; Colon; Colonic Diseases; Colonic Pouches; Deoxycytidine; Diarrhea; Endoscopy, Gastrointestinal; Etanercept; Fluorouracil; Humans; Immunoglobulin G; Immunohistochemistry; Infliximab; Intestinal Mucosa; Methotrexate; Receptors, Tumor Necrosis Factor; Risk Factors; Time Factors; Tumor Necrosis Factor-alpha | 2014 |
[A retrospective study of tegafur/uracil compared with cyclophosphamide, methotrexate, and fluorouracil as adjuvant chemotherapy in patients with node-negative, triple-negative breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cyclophosphamide; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Recurrence; Retrospective Studies; Tegafur; Triple Negative Breast Neoplasms; Uracil | 2014 |
HAGE (DDX43) is a biomarker for poor prognosis and a predictor of chemotherapy response in breast cancer.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Carcinoma; Combined Modality Therapy; Cyclophosphamide; DEAD-box RNA Helicases; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Lymphocytes, Tumor-Infiltrating; Mastectomy; Menopause; Methotrexate; Mitotic Index; Neoplasm Invasiveness; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Prognosis; Proportional Hazards Models; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Treatment Outcome | 2014 |
Prognostic, predictive abilities and concordance of BCL2 and TP53 protein expression in primary breast cancers and axillary lymph-nodes: a retrospective analysis of the Belgian three arm study evaluating anthracycline vs CMF adjuvant chemotherapy.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Axilla; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Humans; Lymph Nodes; Methotrexate; Middle Aged; Prognosis; Proto-Oncogene Proteins c-bcl-2; Retrospective Studies; Treatment Outcome; Tumor Suppressor Protein p53 | 2014 |
[Adenoid cystic carcinoma of the breast:report of 25 cases].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma, Adenoid Cystic; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lung Neoplasms; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Male; Mastectomy; Methotrexate; Middle Aged; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies | 2014 |
Anticancer drug-incorporated layered double hydroxide nanohybrids and their enhanced anticancer therapeutic efficacy in combination cancer treatment.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Survival; Diffusion; Drug Synergism; Fluorouracil; HeLa Cells; Humans; Hydroxides; Methotrexate; Nanocapsules; Nanoconjugates | 2014 |
Cognitive impact of cytotoxic agents in mice.
Topics: Animals; Antineoplastic Agents; Cognition; Cognition Disorders; Cytotoxins; Dose-Response Relationship, Drug; Fear; Fluorouracil; Male; Memory; Methotrexate; Mice; Mice, Inbred C57BL; Reaction Time | 2015 |
Association of ABCB1, β tubulin I, and III with multidrug resistance of MCF7/DOC subline from breast cancer cell line MCF7.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Blotting, Western; Breast Neoplasms; Cell Proliferation; Cell Survival; Docetaxel; Doxorubicin; Drug Resistance, Multiple; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; MCF-7 Cells; Methotrexate; Multidrug Resistance-Associated Protein 2; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Taxoids; Tubulin | 2014 |
Histopathological difficulties in an adolescent lymphoma patient.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Fluorouracil; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Vinblastine; Vincristine | 2015 |
The management of an orbital diffuse large B-cell lymphoma.
Topics: Aged; Antibiotics, Antineoplastic; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphoma, Large B-Cell, Diffuse; Mercaptopurine; Methotrexate; Neoplasm Staging; Orbital Neoplasms; Polyethylene Glycols; Prednisone; Radiotherapy, Adjuvant; Remission Induction; Rituximab; Vinblastine; Vincristine | 2014 |
Model selection and diagnostics for joint modeling of survival and longitudinal data with crossing hazard rate functions.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Computer Simulation; Cyclophosphamide; Cytarabine; Epirubicin; Female; Fluorouracil; Humans; Life Tables; Longitudinal Studies; Methotrexate; Models, Statistical; Survival Analysis | 2014 |
Intraarterial chemotherapy as the first-line therapy in penile cancer.
Topics: Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Fluorouracil; Humans; Infusions, Intra-Arterial; Inguinal Canal; Leucovorin; Lymph Node Excision; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Mitomycin; Neoadjuvant Therapy; Penile Neoplasms; Retrospective Studies | 2014 |
Dual drug delivery of 5-fluorouracil (5-FU) and methotrexate (MTX) through random copolymeric nanomicelles of PLGA and polyethylenimine demonstrating enhanced cell uptake and cytotoxicity.
Topics: Antineoplastic Combined Chemotherapy Protocols; Calorimetry, Differential Scanning; Drug Carriers; Drug Screening Assays, Antitumor; Fluorouracil; HCT116 Cells; Humans; Lactic Acid; Methotrexate; Micelles; Microscopy, Electron, Transmission; Nanostructures; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proton Magnetic Resonance Spectroscopy; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2014 |
Comparative benefit from small tumour size and adjuvant chemotherapy: clues for explaining breast cancer mortality decline.
Topics: Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Proportional Hazards Models; Randomized Controlled Trials as Topic; Survival Analysis | 2014 |
Osteopontin upregulates the expression of glucose transporters in osteosarcoma cells.
Topics: Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Daunorubicin; Etoposide; Fluorouracil; Glucose Transport Proteins, Facilitative; Glucose Transporter Type 1; Glucose Transporter Type 3; Humans; Integrin alphaVbeta3; Membrane Transport Modulators; Methotrexate; Osteopontin; Osteosarcoma; Phloretin; Up-Regulation | 2014 |
Memory loss in chemotherapy-treated rats is exacerbated in high-interference conditions and related to suppression of hippocampal neurogenesis.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Discrimination Learning; Female; Fluorouracil; Hippocampus; Maze Learning; Memory; Memory Disorders; Methotrexate; Neurogenesis; Neuropsychological Tests; Psychomotor Performance; Rats; Rats, Long-Evans | 2015 |
Association of osteoprotegerin and bone loss after adjuvant chemotherapy in early-stage breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Osteoporosis; Osteoprotegerin; Primary Ovarian Insufficiency | 2015 |
Late effects of adjuvant chemotherapy for breast cancer on fine motor function.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cognition; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neuropsychological Tests; Psychomotor Performance; Quality of Life; Survivors; Time Factors | 2015 |
Saddle pulmonary embolus and bronchiolitis obliterans with organizing pneumonia develop simultaneously after first cyclophosphamide, methotrexate, 5FU chemotherapy for breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Renal Cell; Cryptogenic Organizing Pneumonia; Cyclophosphamide; Female; Fluorouracil; Humans; Kidney Neoplasms; Lymph Node Excision; Mastectomy; Methotrexate; Middle Aged; Neoplasms, Multiple Primary; Nephrectomy; Pulmonary Embolism; Tomography, Spiral Computed; Venous Thrombosis | 2015 |
Participation of autophagy in the cytotoxicity against breast cancer cells by cisplatin.
Topics: Adenine; Antineoplastic Agents; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cisplatin; Cyclophosphamide; Docetaxel; Epirubicin; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Taxoids | 2015 |
Adjuvant Metronomic CMF in a Contemporary Breast Cancer Cohort: What's Old Is New.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cohort Studies; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Staging | 2015 |
Antibody-Drug Conjugates (ADCs): Magic Bullets at Last!
Topics: Aniline Compounds; Azo Compounds; Chemistry, Pharmaceutical; Chlorambucil; Dialysis; Fluorouracil; gamma-Globulins; Immune Sera; Mercaptopurine; Methotrexate; Nitrogen Mustard Compounds; Research; Tetracycline; Thiotepa; Ultraviolet Rays; Uracil Mustard | 2015 |
Functional Identification of Target by Expression Proteomics (FITExP) reveals protein targets and highlights mechanisms of action of small molecule drugs.
Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Cell Line, Tumor; Computational Biology; Doxorubicin; Drug Discovery; Fluorouracil; HCT116 Cells; Humans; Methotrexate; Paclitaxel; Proteome; Proteomics; Quinazolines; Small Molecule Libraries; Thiophenes | 2015 |
Postoperative CMF Does Not Ameliorate Poor Outcomes in Women With Residual Invasive Breast Cancer After Neoadjuvant Epirubicin/Docetaxel Chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm, Residual; Prognosis; Proportional Hazards Models; Retrospective Studies | 2015 |
Antithymidylate resistance enables transgene selection and cell survival for T cells in the presence of 5-fluorouracil and antifolates.
Topics: Antineoplastic Agents; Cell Survival; Drug Resistance; Fluorouracil; Folic Acid Antagonists; Humans; Jurkat Cells; Methotrexate; Pemetrexed; T-Lymphocytes; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Transgenes | 2016 |
Characterization of MTAP Gene Expression in Breast Cancer Patients and Cell Lines.
Topics: Adenocarcinoma, Mucinous; Antineoplastic Agents; Azacitidine; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; Estrogen Receptor alpha; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Lymphatic Metastasis; Methotrexate; Organ Specificity; Promoter Regions, Genetic; Purine-Nucleoside Phosphorylase; Receptor, ErbB-2; Receptors, Progesterone; RNA, Small Interfering; Signal Transduction; Triple Negative Breast Neoplasms | 2016 |
Effect of Pretreatment Renal Function on Treatment and Clinical Outcomes in the Adjuvant Treatment of Older Women With Breast Cancer: Alliance A171201, an Ancillary Study of CALGB/CTSU 49907.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Capecitabine; Creatinine; Cyclophosphamide; Female; Fluorouracil; Humans; Kidney Function Tests; Methotrexate; Prognosis; Renal Insufficiency; Survival Rate; Tamoxifen; Treatment Outcome | 2016 |
[Two Cases of Curative Resection of Locally Advanced Rectal Cancer after Preoperative Chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Rectal Neoplasms; Sigmoid Neoplasms; Surgical Stomas | 2015 |
Reduced RanBPM Expression Is Associated with Distant Metastasis in Gastric Cancer and Chemoresistance.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Antimetabolites, Antineoplastic; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Cytoskeletal Proteins; Down-Regulation; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Methotrexate; Neoplasm Invasiveness; Nuclear Proteins; RNA, Catalytic; Signal Transduction; Stomach Neoplasms; Time Factors; Transfection | 2016 |
Response of extensive breast cancer skin metastases to rechallenge with trastuzumab together with low-dose chemotherapy and insulin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Insulin; Methotrexate; Middle Aged; Prednisone; Receptor, ErbB-2; Skin Neoplasms; Trastuzumab; Treatment Outcome; Vincristine | 2016 |
Cardiovascular Disease Risk in a Large, Population-Based Cohort of Breast Cancer Survivors.
Topics: Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Intraductal, Noninfiltrating; Cardiovascular Diseases; Cause of Death; Chemotherapy, Adjuvant; Cisplatin; Cohort Studies; Combined Modality Therapy; Confidence Intervals; Female; Fluorouracil; Heart; Heart Failure; Heart Valve Diseases; Humans; Lymphatic Irradiation; Mastectomy; Methotrexate; Middle Aged; Myocardial Ischemia; Netherlands; Radiotherapy; Registries; Risk Assessment; Survivors; Time Factors; Unilateral Breast Neoplasms | 2016 |
Comparison of MACT and 5Fu+ACT-D chemotherapy regimens in the treatment of low-risk gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Female; Fluorouracil; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Risk; Treatment Outcome; Young Adult | 2016 |
Weekly Multi-agent Chemotherapy (CMF-b) for Advanced Non-melanoma Skin Cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Diseases; Carboplatin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Remission Induction; Renal Insufficiency; Retrospective Studies; Salvage Therapy; Skin Neoplasms | 2016 |
Human dihydrofolate reductase and thymidylate synthase form a complex in vitro and co-localize in normal and cancer cells.
Topics: Antimetabolites, Antineoplastic; Binding Sites; Cell Cycle; Cell Line; Crystallography, X-Ray; DNA; Fibroblasts; Fluorouracil; HCT116 Cells; Humans; Kinetics; Methotrexate; Molecular Docking Simulation; Molecular Dynamics Simulation; Multienzyme Complexes; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Substrate Specificity; Tetrahydrofolate Dehydrogenase; Thermodynamics; Thymidylate Synthase | 2017 |
Environmental enrichment protects against cognitive impairment following chemotherapy in an animal model.
Topics: Animals; Antimetabolites, Antineoplastic; Cognition Disorders; Disease Models, Animal; Drug Therapy; Environment; Female; Fluorouracil; Hippocampus; Methotrexate; Neurogenesis; Rats; Rats, Long-Evans; Spatial Memory | 2016 |
Effectiveness of a Closed-System Transfer Device in Reducing Surface Contamination in a New Antineoplastic Drug-Compounding Unit: A Prospective, Controlled, Parallel Study.
Topics: Antineoplastic Agents; Camptothecin; Cyclophosphamide; Cytarabine; Deoxycytidine; Drug Compounding; Drug Contamination; Fluorouracil; Ganciclovir; Gemcitabine; Humans; Ifosfamide; Irinotecan; Methotrexate; Occupational Exposure; Prospective Studies | 2016 |
Osteopontin splice variants are differential predictors of breast cancer treatment responses.
Topics: Alternative Splicing; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmacological; Biopsy; Breast Neoplasms; Cyclophosphamide; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Immunohistochemistry; Methotrexate; Middle Aged; Osteopontin; Poland; Prognosis; Proportional Hazards Models; Protein Isoforms; Retrospective Studies; Tamoxifen | 2016 |
Chemotherapy With CMF for Triple-Negative Breast Cancer With Carcinoma Erysipelatoides.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Female; Fluorouracil; Humans; Methotrexate; Neoplasms, Multiple Primary; Triple Negative Breast Neoplasms | 2016 |
Isolation, Culture and Identification of Choriocarcinoma Stem-Like Cells from the Human Choriocarcinoma Cell-Line JEG-3.
Topics: AC133 Antigen; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Separation; Choriocarcinoma; Culture Media, Serum-Free; Etoposide; Female; Fluorouracil; Gene Expression; Humans; Hyaluronan Receptors; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Neoplastic Stem Cells; Tumor Burden; Xenograft Model Antitumor Assays | 2016 |
Survival prognostic factors for metachronous second primary head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Deoxycytidine; Docetaxel; Female; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neoplasms, Second Primary; Paclitaxel; Prognosis; Squamous Cell Carcinoma of Head and Neck; Survival Analysis; Taxoids; Treatment Outcome; Young Adult | 2017 |
Levels of miRNA and Hormones in Thoracic Duct Lymph in Rats with Experimental Breast Cancer Induced by N-Methyl-N-Nitrosourea.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Cyclophosphamide; Estradiol; Female; Fluorouracil; Follicle Stimulating Hormone; Luteinizing Hormone; Lymph; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; MicroRNAs; Prolactin; Rats; Rats, Wistar; Thoracic Duct; Thyroglobulin | 2017 |
The Thymus in Experimental Mammary Carcinogenesis and Polychemotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogenesis; Carcinogens; Cell Transformation, Neoplastic; Cyclophosphamide; Epithelial Cells; Female; Fluorouracil; Injections, Intraperitoneal; Lymphocytes; Macrophages; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; Rats, Wistar; Thymus Gland; Thymus Neoplasms | 2017 |
Influence of chemotherapeutic drug-related gene polymorphisms on toxicity and survival of early breast cancer patients receiving adjuvant chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Gene Frequency; Genetic Association Studies; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Kaplan-Meier Estimate; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Polymorphism, Single Nucleotide; Proportional Hazards Models; Prospective Studies | 2017 |
Anticancer drugs and the regulation of Hedgehog genes GLI1 and PTCH1, a comparative study in nonmelanoma skin cancer cell lines.
Topics: Anilides; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Drug Screening Assays, Antitumor; Fluorouracil; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Methotrexate; Patched-1 Receptor; Pyridines; Signal Transduction; Skin Neoplasms; Zinc Finger Protein GLI1 | 2017 |
Induction Methotrexate, Cisplatin, and 5-Fluorouracil Versus Cisplatin and 5-Fluorouracil Followed by Radiotherapy in Pediatric Nasopharyngeal Carcinoma: A Retrospective Analysis in a Tertiary Cancer Center.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemoradiotherapy; Child; Cisplatin; Female; Fluorouracil; Follow-Up Studies; Humans; Induction Chemotherapy; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Methotrexate; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasm Staging; Tomography, X-Ray Computed; Treatment Outcome | 2017 |
Acute aquatic toxicity assessment of six anti-cancer drugs and one metabolite using biotest battery - Biological effects and stability under test conditions.
Topics: Aliivibrio fischeri; Animals; Antineoplastic Agents; Aquatic Organisms; Araceae; Chlorophyta; Cyclophosphamide; Daphnia; Ecotoxicology; Fluorouracil; Imatinib Mesylate; Methotrexate; Toxicity Tests, Acute; Water Pollutants, Chemical | 2017 |
The mTORC1 Signaling Network Senses Changes in Cellular Purine Nucleotide Levels.
Topics: A549 Cells; AMP-Activated Protein Kinases; Animals; Cell Line; Dihydroorotate Dehydrogenase; Enzyme Inhibitors; Fluorouracil; HeLa Cells; Humans; Mechanistic Target of Rapamycin Complex 1; Mercaptopurine; Methotrexate; Mice; Oxidoreductases Acting on CH-CH Group Donors; Phosphoribosylglycinamide Formyltransferase; Purine Nucleotides; Ribosomal Protein S6 Kinases, 70-kDa; RNA Interference; Signal Transduction; Thymidylate Synthase; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2017 |
Neurobiological Mechanisms of Chemotherapy-induced Cognitive Impairment in a Transgenic Model of Breast Cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain; Breast Neoplasms; Cognitive Dysfunction; Cytokines; Disease Models, Animal; Female; Fluorouracil; Learning; Memory; Methotrexate; Mice; Mice, Transgenic; Neurogenesis; Organ Size; Receptors, Virus | 2018 |
Anterior Mediastinal Lymph Nodes in Chemically Induced Breast Cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Cell Proliferation; Cyclophosphamide; Female; Fluorouracil; Injections, Subcutaneous; Lymph Nodes; Lymphatic Metastasis; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mediastinum; Methotrexate; Methylnitrosourea; Plasma Cells; Rats; Rats, Wistar; T-Lymphocytes | 2017 |
Convection enhanced delivery of chemotherapeutic drugs into brain tumour.
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cisplatin; Computer Simulation; Convection; Doxorubicin; Drug Delivery Systems; Fluorouracil; Humans; Methotrexate; Models, Theoretical; Paclitaxel | 2018 |
PAN-811 prevents chemotherapy-induced cognitive impairment and preserves neurogenesis in the hippocampus of adult rats.
Topics: Animals; Antineoplastic Agents; Cognitive Dysfunction; Dentate Gyrus; Discrimination Learning; Disease Models, Animal; Doublecortin Protein; Enzyme Inhibitors; Female; Fluorouracil; Hippocampus; Humans; Learning; Methotrexate; Neurogenesis; Neuroprotective Agents; Pyridines; Rats; Rats, Long-Evans; Ribonucleotide Reductases; Spatial Memory; Thiosemicarbazones | 2018 |
Comparative Proteomics of Dying and Surviving Cancer Cells Improves the Identification of Drug Targets and Sheds Light on Cell Life/Death Decisions.
Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Survival; Fluorouracil; Humans; Methotrexate; Neoplasms; Paclitaxel; Proteome; Proteomics | 2018 |
The effect of adjuvant chemotherapy on survival in Korean patients with node negative T1c, triple negative breast cancer.
Topics: Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Registries; Republic of Korea; Retrospective Studies; Survival Analysis; Triple Negative Breast Neoplasms | 2018 |
The Prosigna gene expression assay and responsiveness to adjuvant cyclophosphamide-based chemotherapy in premenopausal high-risk patients with breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Gene Expression Profiling; Humans; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Predictive Value of Tests; Premenopause; Prognosis; Receptor, ErbB-2; Retrospective Studies; Risk Assessment | 2018 |
Experience in Intra-arterial Chemotherapy using Two Protocols for the Treatment of OSCC over Two Decades at the University Hospital Vienna.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Recurrence, Local; Neoplasm Staging; Retrospective Studies; Treatment Outcome; Young Adult | 2018 |
Effect of Neoadjuvant and Adjuvant Therapy of Experimental Breast Cancer on the Structure of Mesenteric Lymph Nodes.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Fluorouracil; Lymph Nodes; Lymphocyte Subsets; Macrophages; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mast Cells; Mesentery; Methotrexate; Methylnitrosourea; Neoadjuvant Therapy; Neutrophils; Rats; Rats, Wistar | 2018 |
Targeting of TMPRSS4 sensitizes lung cancer cells to chemotherapy by impairing the proliferation machinery.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cisplatin; Docetaxel; Etoposide; Fluorouracil; HEK293 Cells; Humans; Lung Neoplasms; Membrane Proteins; Methotrexate; Mice; Molecular Targeted Therapy; Pemetrexed; Serine Endopeptidases | 2019 |
Germline Genetic Variants in GATA3 and Breast Cancer Treatment Outcomes in SWOG S8897 Trial and the Pathways Study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; GATA3 Transcription Factor; Germ-Line Mutation; Humans; Methotrexate; Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Survival Rate | 2019 |
Long noncoding RNA H19 promotes chemotherapy resistance in choriocarcinoma cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Choriocarcinoma; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Inhibitory Concentration 50; Methotrexate; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; RNA, Long Noncoding; Signal Transduction; TOR Serine-Threonine Kinases; Wound Healing | 2019 |
Fluoropyrimidine with or without platinum as first-line chemotherapy in patients with advanced gastric cancer and severe peritoneal metastasis: a multicenter retrospective study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Ascites; Cisplatin; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Malnutrition; Methotrexate; Middle Aged; Neutropenia; Organoplatinum Compounds; Oxonic Acid; Peritoneal Neoplasms; Progression-Free Survival; Pyridines; Retrospective Studies; Stomach Neoplasms; Tegafur; Treatment Outcome; Withholding Treatment; Young Adult | 2019 |
Effect of tissue permeability and drug diffusion anisotropy on convection-enhanced delivery.
Topics: Anisotropy; Blood Flow Velocity; Blood-Brain Barrier; Carmustine; Cisplatin; Convection; Diffusion; Doxorubicin; Drug Delivery Systems; Extracellular Fluid; Fluorouracil; Methotrexate; Models, Theoretical; Paclitaxel; Permeability; Pharmaceutical Preparations; Pressure; Spatial Analysis | 2019 |
Proteome Integral Solubility Alteration: A High-Throughput Proteomics Assay for Target Deconvolution.
Topics: A549 Cells; Algorithms; Antimetabolites; Cell Line, Tumor; Chromatography, Liquid; Fluorouracil; High-Throughput Screening Assays; Humans; Methotrexate; Protease Inhibitors; Protein Stability; Proteome; Proteomics; Reproducibility of Results; Solubility; Tandem Mass Spectrometry; Temperature | 2019 |
Potentiation of Glucagon-Like Peptide-2 Dynamics by Methotrexate Administration in Rat Small Intestine.
Topics: Animals; Antimetabolites, Antineoplastic; Dipeptidyl Peptidase 4; Fluorouracil; Glucagon-Like Peptide 2; Glucagon-Like Peptide-2 Receptor; Insulin-Like Growth Factor I; Intestine, Small; Male; Methotrexate; Rats, Wistar | 2019 |
Convection enhanced delivery of anti-angiogenic and cytotoxic agents in combination therapy against brain tumour.
Topics: Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Carmustine; Cisplatin; Convection; Cytotoxins; Doxorubicin; Fluorouracil; Humans; Methotrexate; Microvessels; Models, Biological; Paclitaxel | 2020 |
Early Effects of Cyclophosphamide, Methotrexate, and 5-Fluorouracil on Neuronal Morphology and Hippocampal-Dependent Behavior in a Murine Model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; CA1 Region, Hippocampal; Chemotherapy, Adjuvant; Cyclophosphamide; Dendrites; Dendritic Spines; Disease Models, Animal; Female; Fluorouracil; Hippocampus; Methotrexate; Mice; Neurons; Quality of Life | 2020 |
Study protocol for the assessment of nurses internal contamination by antineoplastic drugs in hospital centres: a cross-sectional multicentre descriptive study.
Topics: Antineoplastic Agents; Biomarkers; Cross-Sectional Studies; Cyclophosphamide; Doxorubicin; Environmental Monitoring; Fluorouracil; France; Humans; Ifosfamide; Methotrexate; Multicenter Studies as Topic; Nursing Staff, Hospital; Observational Studies as Topic; Occupational Exposure; Oncology Nursing; Prospective Studies; Research Design; Self Report | 2019 |
Diversity of the Senescence Phenotype of Cancer Cells Treated with Chemotherapeutic Agents.
Topics: Antineoplastic Agents; Cell Proliferation; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Doxorubicin; Fluorouracil; Humans; Irinotecan; Methotrexate; Neoplasms; Oxaliplatin; Paclitaxel; Phenotype; Tumor Cells, Cultured | 2019 |
Prophylactic piperacillin administration in pediatric patients with solid tumors following different intensities of chemotherapy.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child; Child, Preschool; Drug Resistance, Microbial; Female; Fever; Fluorouracil; Humans; Infant; Leucovorin; Male; Methotrexate; Neuroblastoma; Neutropenia; Piperacillin; Retrospective Studies | 2020 |
Global treatment patterns and outcomes among patients with recurrent and/or metastatic head and neck squamous cell carcinoma: Results of the GLANCE H&N study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Australia; Brazil; Bridged-Ring Compounds; Canada; Cetuximab; Confidence Intervals; Europe; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Platinum Compounds; Republic of Korea; Retrospective Studies; Squamous Cell Carcinoma of Head and Neck; Taiwan; Taxoids; Treatment Outcome | 2020 |
Zig Zag AFM Protocol Reveals New Intermediate Folding States of Bacteriorhodopsin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bacteriorhodopsins; Doxorubicin; Fluorouracil; Methotrexate; Protein Unfolding | 2020 |
Quantification of healthcare workers' exposure to cyclophosphamide, ifosfamide, methotrexate, and 5-fluorouracil by 24-h urine assay: A descriptive pilot study.
Topics: Adult; Antineoplastic Agents; Canada; Chromatography, Liquid; Cyclophosphamide; Environmental Monitoring; Fluorouracil; Health Personnel; Humans; Ifosfamide; Methotrexate; Middle Aged; Occupational Exposure; Personal Protective Equipment; Pharmacy Technicians; Pilot Projects; Young Adult | 2020 |
"Watson-Crick G[triple bond, length as m-dash]C"-inspired supramolecular nanodrug of methotrexate and 5-fluorouracil for tumor microenvironment-activatable self-recognizing synergistic chemotherapy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytosine; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Fluorouracil; Guanine; Humans; Macromolecular Substances; Mammary Neoplasms, Experimental; Methotrexate; Mice; Molecular Structure; Nanoparticles; Particle Size; Surface Properties; Tumor Microenvironment | 2020 |
Morphological Study of Mesenteric Lymph Nodes in Rats with Experimental Breast Cancer Treated with Fragmented Double-Stranded DNA.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; DNA; DNA Fragmentation; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Mastectomy; Mesentery; Methotrexate; Methylnitrosourea; Rats; Rats, Wistar; Treatment Outcome | 2020 |
In Vitro Release of 5-Fluorouracil and Methotrexate from Different Thermosensitive Chitosan Hydrogel Systems.
Topics: Antimetabolites, Antineoplastic; Calorimetry, Differential Scanning; Chitosan; Drug Delivery Systems; Drug Liberation; Fluorouracil; Hydrogels; Methotrexate; Temperature | 2020 |
Predictive Value of Molecular Subtypes in Premenopausal Women with Hormone Receptor-positive Early Breast Cancer: Results from the ABCSG Trial 5.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Goserelin; Humans; Ki-67 Antigen; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Premenopause; Progression-Free Survival; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 2020 |
Glutathione S-transferase Polymorphisms in Head and Neck Squamous Cell Carcinoma Treated with Chemotherapy and/or Radiotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chemoradiotherapy; Cisplatin; Female; Fluorouracil; Follow-Up Studies; Genetic Predisposition to Disease; Glutathione S-Transferase pi; Haplotypes; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Polymorphism, Genetic; Prognosis; Retrospective Studies; Risk Factors; Squamous Cell Carcinoma of Head and Neck | 2020 |
Differential Benefit of Adjuvant Docetaxel-Based Chemotherapy in Patients With Early Breast Cancer According to Baseline Body Mass Index.
Topics: Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Cyclophosphamide; Disease-Free Survival; Docetaxel; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Randomized Controlled Trials as Topic; Receptors, Estrogen; Retrospective Studies; Survival Rate | 2020 |
Is the first-line treatment of keratoacanthomas surgical excision or injection of intralesional chemotherapy?
Topics: Dermatologic Agents; Fluorouracil; Humans; Injections, Intralesional; Keratoacanthoma; Methotrexate; Mohs Surgery | 2020 |
Medical therapy for keratoacanthomas.
Topics: Fluorouracil; Humans; Keratoacanthoma; Methotrexate | 2020 |
Comparative cytotoxic and antiproliferative profile of methotrexate and fluorouracil on different ocular cells.
Topics: Apoptosis; Cells, Cultured; Fluorouracil; Humans; Immunosuppressive Agents; Methotrexate; Retinal Pigment Epithelium; Vitreoretinopathy, Proliferative | 2021 |
Occurrence and ecotoxicity of cytostatic drugs 5-fluorouracil and methotrexate in the freshwater unionid Elliptio complanata.
Topics: Animals; Bivalvia; Cytostatic Agents; Digestive System; Fluorouracil; Fresh Water; Gonads; Methotrexate; Water Pollutants, Chemical | 2021 |
Insight into the Sorption of 5-Fluorouracil and Methotrexate onto Soil-pH, Ionic Strength, and Co-Contaminant Influence.
Topics: Adsorption; Cadmium; Environmental Monitoring; Environmental Pollutants; Fluorouracil; Hydrogen-Ion Concentration; Methotrexate; Metoprolol; Osmolar Concentration; Plant Extracts; Soil; Soil Pollutants | 2021 |
Nurses' internal contamination by antineoplastic drugs in hospital centers: a cross-sectional descriptive study.
Topics: Adult; Antineoplastic Agents; Biological Monitoring; Cross-Sectional Studies; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Hospitals; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Nurses; Nursing Staff, Hospital; Occupational Exposure; Surveys and Questionnaires; Young Adult | 2021 |
CMF and MET treatment induce cognitive impairment through upregulation of IL-1α in rat brain.
Topics: Animals; Antineoplastic Agents; Brain; Cognitive Dysfunction; Cyclophosphamide; Dose-Response Relationship, Drug; Fluorouracil; Injections, Intraperitoneal; Interleukin-1; Male; Methotrexate; Rats; Up-Regulation | 2021 |
A Retrospective Analysis of Metronomic Cyclophosphamide, Methotrexate, and Fluorouracil (CMF) Versus Docetaxel and Cyclophosphamide (TC) as Adjuvant Treatment in Early Stage, Hormone Receptor Positive, HER2 Negative Breast Cancer.
Topics: Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Docetaxel; Female; Fluorouracil; Humans; Methotrexate; Retrospective Studies; Taxoids | 2022 |
Elucidating the mechanism underlying cognitive dysfunction by investigating the effects of CMF and MET treatment on hippocampal neurons.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cognitive Dysfunction; Cyclophosphamide; Female; Fluorouracil; Hippocampus; Humans; Metformin; Methotrexate; Neurons | 2022 |
Towards establishment of a plant-based model to assess the novel anti-cancerous lead molecule(s): An in silico, in vivo and in vitro assessment of some potential anti-cancerous drugs on Lathyrus sativus L.
Topics: Colchicine; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Etoposide; Fluorouracil; Humans; Lathyrus; Methotrexate; Pemetrexed; Plant Proteins; RNA; Topotecan | 2022 |
Heterocyclic Compounds: Importance in Anticancer Drug Discovery.
Topics: Antineoplastic Agents; Daunorubicin; Doxorubicin; Fluorouracil; Heterocyclic Compounds; Humans; Methotrexate; Neoplasms; Pharmaceutical Preparations; Vinblastine; Vincristine | 2022 |
Effects of CMF and MET on glutamate and dopamine levels in the brain, and their impact on cognitive function.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain; Breast Neoplasms; Cognition; Cyclophosphamide; Diabetes Mellitus, Type 2; Dopamine; Female; Fluorouracil; Glutamic Acid; Humans; Metformin; Methotrexate; Rats | 2022 |
MORPHOLOGICAL FEATURES OF TUBULAR BONES REPARATIVE REGENERATION UNDER THE INFLUENCE OF ANTITUMOR CHEMOTHERAPEUTICS.
Topics: Animals; Bone Regeneration; Doxorubicin; Fluorouracil; Humans; Methotrexate; Osteogenesis; Rats | 2022 |
Unraveling the Mechanisms of Clinical Drugs-Induced Neural Tube Defects Based on Network Pharmacology and Molecular Docking Analysis.
Topics: Animals; Anticonvulsants; Antineoplastic Agents; Class I Phosphatidylinositol 3-Kinases; ErbB Receptors; Female; Fluorouracil; Hydroxyurea; Methotrexate; Mice; Molecular Docking Simulation; Network Pharmacology; Neural Tube Defects; Phosphatidylinositol 3-Kinases; Pregnancy; Tretinoin; Valproic Acid | 2022 |
Development and application of a liquid chromatography coupled to mass spectrometry method for the simultaneous determination of 23 antineoplastic drugs at trace levels.
Topics: Antineoplastic Agents; Busulfan; Carboplatin; Chromatography, Liquid; Cyclophosphamide; Cytarabine; Dacarbazine; Daunorubicin; Docetaxel; Doxorubicin; Epirubicin; Etoposide; Fluorouracil; Ganciclovir; Humans; Idarubicin; Ifosfamide; Irinotecan; Methanol; Methotrexate; Oxaliplatin; Paclitaxel; Pemetrexed; Tandem Mass Spectrometry; Topotecan; Vinblastine; Vincristine; Water | 2022 |
Evaluation and validation of chemotherapy-specific diarrhoea and histopathology in rats.
Topics: Animals; Antineoplastic Agents; Atrophy; Body Weight; Diarrhea; Doxorubicin; Fluorouracil; Idarubicin; Intestinal Mucosa; Irinotecan; Male; Methotrexate; Mucositis; Rats; Rats, Wistar | 2022 |
Cognitive impairment and elevated peripheral cytokines in breast cancer patients receiving chemotherapy.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cognitive Dysfunction; Cyclophosphamide; Cytokines; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Interleukin-1beta; Interleukin-6; Methotrexate | 2022 |
Breast cancer therapy in women under 35 years and between 50 and 69 years: influence of the observation period.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Tamoxifen | 2023 |
Combination of Copper Metallodendrimers with Conventional Antitumor Drugs to Combat Cancer in In Vitro Models.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Copper; Dendrimers; Doxorubicin; Female; Fluorouracil; Humans; Ligands; Methotrexate | 2023 |
Antineoplastic drugs in environmentally relevant concentrations cause endocrine disruption and testicular dysfunction in experimental conditions.
Topics: Animals; Antineoplastic Agents; Drinking Water; Endocrine Disruptors; Fluorouracil; Male; Methotrexate; Rats; Rats, Wistar; Water Pollution, Chemical | 2023 |
A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance.
Topics: Fluorouracil; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Tetrahydrofolate Dehydrogenase | 2023 |
In-vitro and in-vivo assessment of pH-responsive core-shell nanocarrier system for sequential delivery of methotrexate and 5-fluorouracil for the treatment of breast cancer.
Topics: Animals; Drug Carriers; Female; Fluorouracil; Hydrogen-Ion Concentration; Methotrexate; Nanoparticles; Neoplasms | 2023 |