fluorouracil and mesna

fluorouracil has been researched along with mesna in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's4 (30.77)18.2507
2000's2 (15.38)29.6817
2010's3 (23.08)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Chen, R; Farquhar, D; Khan, S1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Becher, R; Höfeler, H; Kloke, O; May, D; Niederle, N; Richter, R; Scheulen, ME; Schmidt, CG; Wandl, U1
Dorr, RT1
Becher, R; Höfeler, H; Kloke, O; Kurschel, E; Schilcher, RB; Schmidt, CG; Wandl, U; Weinhardt, O1
Petru, E; Schmähl, D1
Burba-Anczewska, I; Danysz, A; Kłosiewicz, S; Pniewska, A; Wierzba, K1
Acito, L; Angiona, S; Bella, M; Carlini, P; Di Costanzo, F; Donati, D; Maggian, P; Mazzocchi, B; Tagliaventi, M; Zironi, S1
Gutweiler, JR; Kim, HB; Kozakewich, HP; Marcus, KJ; Shamberger, RC; Weldon, CB; Yu, DC1
Hanege, FM; Kalcioglu, MT; Kokten, N; Tuysuz, O; Zenginkinet, T1

Reviews

2 review(s) available for fluorouracil and mesna

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Chemoprotectants for cancer chemotherapy.
    Seminars in oncology, 1991, Volume: 18, Issue:1 Suppl 2

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Cisplatin; Cyclophosphamide; Fluorouracil; Humans; Ifosfamide; Leucovorin; Mesna; Methotrexate; Neoplasms; Razoxane; Sulfhydryl Compounds; Uridine

1991

Trials

1 trial(s) available for fluorouracil and mesna

ArticleYear
High-dose folinic acid and fluorouracil with or without ifosfamide is an inactive combination in advanced pancreatic cancer. A randomized phase II study of the Italian Oncology Group for Clinical Research (G.O.I.R.C.).
    American journal of clinical oncology, 1996, Volume: 19, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Ifosfamide; Leucovorin; Male; Mesna; Middle Aged; Pancreatic Neoplasms

1996

Other Studies

10 other study(ies) available for fluorouracil and mesna

ArticleYear
5'-[4-(Pivaloyloxy)-1,3,2-dioxaphosphorinan-2-yl]-2'-deoxy-5-fluorouridine: a membrane-permeating prodrug of 5-fluoro-2'-deoxyuridylic acid (FdUMP).
    Journal of medicinal chemistry, 1995, Feb-03, Volume: 38, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Division; Cell Membrane; CHO Cells; Cricetinae; Esterases; Fluorodeoxyuridylate; Leukemia P388; Male; Mice; Phosphoric Monoester Hydrolases; Prodrugs; Swine

1995
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Ifosfamide, methotrexate and 5-fluorouracil for pretreated advanced breast cancer.
    Oncology, 1991, Volume: 48, Issue:6

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Fluorouracil; Hematopoiesis; Humans; Ifosfamide; Liver Neoplasms; Mesna; Methotrexate; Middle Aged; Risk Factors; Survival Analysis

1991
Ifosfamide, methotrexate, and 5-fluorouracil in advanced pretreated breast cancer.
    Seminars in oncology, 1989, Volume: 16, Issue:1 Suppl 3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Fluorouracil; Humans; Ifosfamide; Menopause; Mesna; Methotrexate; Middle Aged; Neoplasm Metastasis; Remission Induction; Time Factors

1989
Anticancer drugs: second malignancies--risk reduction.
    Cancer treatment reviews, 1987, Volume: 14, Issue:3-4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Fluorouracil; Male; Mesna; Methotrexate; Neoplasms, Multiple Primary; Rats; Vincristine

1987
The effect of sulfhydryl compounds on 5-fluorouracil toxicity and distribution.
    Archivum immunologiae et therapiae experimentalis, 1983, Volume: 31, Issue:3

    Topics: Animals; Cysteine; Fluorouracil; Glutathione; Kinetics; Lethal Dose 50; Male; Mesna; Mice; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1983
Hepatoblastoma presenting with focal nodular hyperplasia after treatment of neuroblastoma.
    Journal of pediatric surgery, 2008, Volume: 43, Issue:12

    Topics: Adrenal Gland Neoplasms; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carboplatin; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Etoposide; Fluorouracil; Focal Nodular Hyperplasia; Granulocyte Colony-Stimulating Factor; Hepatectomy; Hepatoblastoma; Humans; Ifosfamide; Immunoglobulin G; Incidental Findings; Liver Neoplasms; Male; Melphalan; Mesna; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Neuroblastoma; Radiotherapy, Adjuvant; Tomography, X-Ray Computed; Vincristine

2008
Inhibitory effect of mesna and 5-fluorouracil on propylene glycol-induced cholesteatoma in rats.
    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2021, Volume: 41, Issue:5

    Topics: Animals; Cholesteatoma, Middle Ear; Fluorouracil; Humans; Mesna; Propylene Glycols; Rats; Rats, Wistar

2021
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