fluorouracil has been researched along with melphalan in 351 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 263 (74.93) | 18.7374 |
| 1990's | 41 (11.68) | 18.2507 |
| 2000's | 30 (8.55) | 29.6817 |
| 2010's | 16 (4.56) | 24.3611 |
| 2020's | 1 (0.28) | 2.80 |
| Authors | Studies |
|---|---|
| Almahmood, M; Hall, IH; Loeffler, LJ; Sajadi, Z | 1 |
| Hall, IH; Loeffler, LJ; Sajadi, Z | 1 |
| Hall, IH; Ibuka, T; Lee, KH; Mar, EC | 1 |
| Hall, IH; Lee, KH; Mar, EC; Okamoto, M | 1 |
| Hall, IH; Lee, KH; Wu, YS | 1 |
| Atassi, G; Baron, M; Bissery, MC; Cros, S; Gebel-Servolles, P; Giorgi-Renault, S; Lavelle, F; Paoletti, C; Renault, J | 1 |
| Allen, TM; Knaus, EE; Kumar, R; Tovell, DR; Tyrrell, DL; Wiebe, LI; Xu, LH | 1 |
| Hansch, C; Khwaja, TA; Selassie, CD | 1 |
| Hall, IH; Kashani, M; Loeffler, LJ; Sajadi, Z | 1 |
| Allen, TM; Balzarini, J; De Clercq, E; Dimmock, JR; Kandepu, NM; Kowalchuk, TP; LeClerc, R; Motaganahalli, NL; Nazarali, AJ; Prisciak, JS; Pugazhenthi, U; Quail, JW; Santos, CL | 1 |
| Gust, R; Kircher, B; Ott, I; Schmidt, K; Schumacher, P; Wiglenda, T | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Geisert, EE; Hong, SS; Kang, GS; Kirichenko, OV; Li, W; Miller, DD; Mohler, ML; Patil, R; Rakov, IM | 1 |
| Alcorn, J; Balzarini, J; Das, U; De Clercq, E; Dimmock, JR; Sharma, RK; Shrivastav, A | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Balzarini, J; Clercq, ED; Dimmock, JR; Jha, A; Manavathu, EK; Mukherjee, C; Nienaber, KH; Parmar, VS; Prasad, AK; Sharma, RK; Shrivastav, A; Stables, JP; Zello, GA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Benfenati, E; Raska, I; Toropov, AA; Toropova, AP | 1 |
| Balzarini, J; Das, U; De Clercq, E; Dimmock, JR; Hashimoto, K; Kawase, M; Pati, HN; Sakagami, H | 1 |
| Das, S; Das, U; Dimmock, JR; Gorecki, DK; Iwamoto, S; Kawase, M; Matsuta, T; Molnár, J; Sakagami, H; Serly, J; Umemura, N | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Aguilera, RJ; Balzarini, J; Das, S; Das, U; De Clercq, E; Dimmock, JR; Dimmock, SG; Gorecki, DK; Lema, C; Ortega, NM; Robles-Escajeda, E; Santiago-Vazquez, Y; Varela-Ramírez, A | 1 |
| Balzarini, J; Das, U; De Clercq, E; Dimmock, JR; Dimmock, SG; Iwamoto, S; Karki, SS; Kawase, M; Sakagami, H; Umemura, N | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Davis, TE; Rose, DP | 1 |
| Ahmann, DL; Bisel, HF; Edmonson, JH; Frytak, S; Hahn, RG; Ingle, JN; O'Connell, MJ; O'Fallon, JR; Payne, WS; Rubin, J; Scanlon, PW | 1 |
| Stoll, BA | 1 |
| Firusian, N; Hossfeld, DK; John, V | 1 |
| Anderson, T; Bender, RA; Canellos, GP; Chabner, BA; DeVita, VT; Fisher, RI; Hubbard, SP; Simon, RM; Young, RC | 1 |
| Neijt, JP; Pinedo, HM; Roozendaal, KJ; Struyvenberg, A; van Lindert, AC; Vendrik, CP | 1 |
| Costa, J; Garvin, AJ; Ozols, RF; Simon, RM; Young, RC | 1 |
| Fisher, RI; Young, RC | 1 |
| Livingston, RB | 1 |
| Bast, RC; Borsos, T; Greene, SL; Ohanian, SH; Rapp, HJ; Segerling, M; Zbar, B | 1 |
| Barton, B; Carbone, P; Economou, S; Fisher, B; Fisher, ER; Foster, R; Frelick, R; Glass, A; Lerner, H; Levitt, M; MacFarlane, J; Margolese, R; Plotkin, D; Redmond, C; Shibata, H; Such, E; Volk, H | 1 |
| Band, P; Bauer, M; Carbone, PP; Tormey, D | 1 |
| Louie, AC; Muggia, FM; Rozencweig, M; von Hoff, DD | 1 |
| Fisher, B | 4 |
| Berman, R; Bird, GG; Bunch, GA; Gajjar, PD; Giles, GR; Hall, R; Malhotra, A | 1 |
| Klahr, C; Presant, CA; Ratkin, G | 1 |
| Seradour, B; Thomas, M | 1 |
| Drings, P; Kaufmann, M; Kubli, F; Lammers, G | 1 |
| Boyes, DA; Gerulath, A; Klaassen, DJ; Levitt, M; Miller, AB; Pearson, JG | 1 |
| Arseneau, JC; Brodovsky, H; Bruckner, HW; Creech, R; Davis, TE; Falkson, G; Greenspan, E; Horton, J; Pagano, M; Slayton, RW | 1 |
| Mason, B; Stephens, EJ; Wood, HF | 1 |
| DeVita, VT; Weiss, RB | 1 |
| Botnick, LE; Hannon, EC; Hellman, S | 1 |
| Rutledge, F; Smith, JP; Stanhope, CR | 1 |
| Fraumeni, JF; Hoover, R; Reimer, RR; Young, RC | 1 |
| Bruntsch, U; Gallmeier, WM | 1 |
| Blessing, J; Lewis, GC | 1 |
| Barber, HR; Buterman, I; Kakarla, R; Kwon, T | 1 |
| Allegra, JC; Lippman, ME | 1 |
| Jochimsen, PR; Sherman, BM; Wallace, RB | 1 |
| Cześnin, K; Ploch, E; Sablińska, B | 1 |
| Burnett, W; Furnival, CM; Gough, IR | 1 |
| Barlow, JJ; Lele, SB; Piver, MS | 1 |
| Vogel, CL | 1 |
| DiBenedetto, J; Evans, JT; Mittelman, A; Moayeri, H | 1 |
| Kornfeld, S; Minnich, V; Smith, ME; Thompson, D | 1 |
| Bergsagel, DE | 2 |
| Bird, GG; Brown, GJ; Bullen, BR; Bunch, GA; Giles, GR; Hall, R; Malhotra, A | 1 |
| Dubois, JB; Serrou, B | 1 |
| Carbone, PP | 3 |
| Rutledge, FN; Smith, JP | 3 |
| Canellos, GP; Chabner, BA; DeVita, VT; Hubbard, SP; Young, RC | 1 |
| Barlow, JJ; Chung, WS; Lee, FT; Piver, S; Vongtama, V | 1 |
| Anderson, JC; Fugmann, RA; Martin, DS; Stolfi, RL | 1 |
| Kane, RD; Paulson, DF; Stocks, LH | 1 |
| Barlow, JJ; Piver, MS | 1 |
| Holland, JF | 3 |
| Bruckner, HW; Cohen, CJ; Deppe, G | 2 |
| Medina, D; Shepherd, F | 1 |
| Band, PR; Canellos, GP; Klaasen, DJ; Pocock, SJ; Sears, ME; Taylor, SG | 1 |
| Kane, RD; Mickey, DD; Paulson, DF | 1 |
| Bulbrook, RD | 1 |
| Band, PR; Carbone, PP | 1 |
| Håkansson, L | 1 |
| Mitchell, MS | 1 |
| Bates, TD; Brinkley, D; Edelstyn, G; MacRae, KD; Spittle, M; Wheeler, T | 1 |
| Rutledge, F; Smith, JP | 2 |
| Barlow, JJ; Lee, FJ; Piver, MS; Vongtama, V | 1 |
| Dahn, I; Håkansson, L; Huldt, B | 1 |
| Freireich, EJ; Gottlieb, JA; Loo, TL; Mahagaokar, S; Rao, PN | 1 |
| Dencker, H; Håkansson, L; Tropé, C | 1 |
| Hreshchyshyn, MM | 1 |
| Fisher, B; Rubin, H; Saffer, E; Wolmark, N | 1 |
| Bernhardt, G; Birnböck, H; Reile, H; Schönenberger, H; Spruss, T | 1 |
| Belinson, JL; Bocklage, T; Lee, KR | 1 |
| Weiss, RB | 1 |
| Cold, S; Pfeiffer, P; Rose, C | 1 |
| Derazne, E; Kahan, E; Klein, B; Lurie, H; Rakowsky, E | 1 |
| Lesperance, ML; Mueller, CB | 1 |
| Brockschmidt, JK; Cooper, MR; Ferree, C; Jackson, DV; Muss, HB; Richards, F; Spurr, CL; White, DR | 1 |
| Cheung, NK; Exelby, PR; Gulati, SC; Kushner, BH; Kwon, JH; O'Reilly, RJ | 1 |
| Carpenter, JT; Levine, EG; Raczynski, JM | 1 |
| Ben-Efraim, S; Burstein, Y; Harshemesh, H; Ophir, R; Pecht, M; Trainin, N | 1 |
| Barranco, SC; Beasley, EG; Jenkins, VK; MacLean, KK; Townsend, CM; Weintraub, B | 1 |
| Dorr, A | 1 |
| Bowman, D; Brown, AM; Dimitrov, NV; Fisher, B; Glass, AG; Legault-Poisson, S; Margolese, RG; Redmond, C; Wickerham, DL; Wolmark, N | 1 |
| Brown, A; Dimitrov, N; Fisher, B; Fisher, ER; Glass, A; Margolese, R; Pilch, Y; Redmond, C; Wickerham, DL; Wolmark, N | 1 |
| Brusentsov, NA; Glazkova, TIu; Iavorskaia, NP; Iurchenko, NIa | 1 |
| Ehrsson, H; Eksborg, S | 1 |
| Markman, M | 2 |
| Iwabuchi, M; Takahashi, K | 1 |
| Ishige, H; Iwasawa, H; Sekiya, S; Takamizawa, H; Tanaka, N; Tokita, H | 1 |
| Jestrimski, KW; Lowenthal, RM | 1 |
| Ezaki, T; Fujioka, T; Miyagi, N; Nakatani, K; Sakamoto, K; Shiratori, T; Sugisaki, T; Watanabe, A | 1 |
| Dimery, IW; Fields, R; Goepfert, H; Harrison, ML; Oswald, MJ; Peters, LJ | 1 |
| Furusawa, M; Hara, Y; Kameda, K; Nakane, H; Nohtsuka, T; Saeki, K; Seo, Y; Sonoda, T; Tomoda, H; Tsujitani, S | 1 |
| McIntosh-Lowe, NL; Rose, CM; Teicher, BA | 1 |
| Hoshino, A; Itou, T; Kamiya, O; Nagata, K; Ohara, K; Ono, Y; Saito, M; Yamamoto, K | 1 |
| Apple, JS; Baber, C; Paulson, DF; Putman, CE | 1 |
| Wang, QL | 1 |
| Fisher, B; Redmond, C; Wolmark, N | 1 |
| Bowman, D; Fisher, B; Fisher, ER; Jochimsen, P; Legault-Poisson, S; Redmond, C; Sass, R; Schipper, H; Wickerham, DL; Wolmark, N | 1 |
| Athens, J; Constanzi, JJ; Gad-el-Mawla, N; Glucksberg, H; Green, S; Hoogstraten, B; Maloney, T; Metch, B; Osborne, CK; Rivkin, SE | 1 |
| Arteaga, CL; Kitten, L; Osborne, CK | 1 |
| Fisher, B; Wolmark, N | 5 |
| Bornstein, R; Bowman, D; Brown, A; Fisher, B; Fisher, ER; Legault-Poisson, S; Plotkin, D; Redmond, C; Wolmark, N; Wolter, J | 1 |
| Osborne, CK | 1 |
| Portnoĭ, AS | 1 |
| Ben-Efraim, S; Ophir, R; Shoval, S | 1 |
| Brown, SD; Didolkar, MS; Elias, EG; Morris, DM | 1 |
| Kaufman, EE; Marymont, JV | 1 |
| Emerman, JT; Fiedler, EE; Rebbeck, PM; Tolcher, AW | 1 |
| Gantchev, GT; Getov, CM; Ilarionova, MV; Maneva, KM; Silyanovska, KK; Todorov, DK | 1 |
| Erlichman, C; Vidgen, D; Wu, A | 1 |
| Bonadonna, G; Buzdar, A; Jones, SE; Montague, E; Moon, TE; Powles, T; Rivkin, S; Valagussa, P | 1 |
| Foster, BJ; Grotzinger, KR; Hamilton, TC; McKoy, WM; Rubinstein, LV | 1 |
| Mouridsen, HT | 1 |
| Brenner, DE | 1 |
| Fisher, B; Fisher, ER; Redmond, C; Wolmark, N | 1 |
| Costanzi, JJ; Green, S; McDivitt, RW; O'Bryan, R; Osborne, CK; Rivkin, SE; Stephens, RL | 1 |
| Berry, WR; Cox, EB; Graham, SD; Laszlo, J; Paulson, DF; Walker, A | 1 |
| Brown, A; Dimitrov, N; Fisher, B; Legault-Poisson, S; Prager, D; Redmond, C; Schipper, H; Wickerham, DL; Wittliff, J; Wolmark, N | 1 |
| Lesnaja, NA | 1 |
| Lesnaia, NA | 1 |
| Grygiel, J; Raghavan, D | 1 |
| Clark, GM; Dressler, LG; McGuire, WL; Owens, MA | 1 |
| Meyer, JS | 1 |
| Fisher, ER | 1 |
| Gau, TC | 1 |
| Constanzi, J; Foulkes, M; Gad-el-Mawla, N; Glucksberg, H; Osborne, CK; Rivkin, SE; Tranum, W | 1 |
| Binsack, T; Sauer, H; Wilmanns, W | 1 |
| Cooper, RG | 1 |
| Carter, SK | 4 |
| Henderson, IC | 1 |
| Durrant, KR; Giraud-Saunders, AM; Gough, MH; McPherson, K; Paine, CH; Vessey, MP | 1 |
| Ozhiganov, EL; Platinskiĭ, LV; Sokolova, VD | 1 |
| Arseneau, JC; Brodovsky, HS; Bruckner, HW; Creech, RH; Davis, TE; Dinse, GE; Falkson, G; Greenspan, EM; Hahn, RG; Pagano, M | 1 |
| Come, SE; Gargan, TJ; Satwicz, PR | 1 |
| Delgado, G; McLaughlin, EK; Smith, FP; Tuholski, N | 1 |
| Alberts, DS; Mason, N; Salmon, SE; Young, L | 1 |
| Franz, G; Lietz, H | 1 |
| Emrich, LJ; Lele, SB; Patsner, B; Piver, MS | 1 |
| Boyd, NF; Campbell, JA; Elhakim, T; Heasman, KZ; Sutherland, HJ | 1 |
| Heppner, GH; Miller, BE; Miller, FR | 1 |
| Kühböck, J | 1 |
| Rieche, K; Wand, H | 1 |
| Abendroth, K; Siering, VH | 1 |
| Blackwood, JM; Keller, JW; Pace, WG | 1 |
| Fomina, IP; Navashin, SM; Osokina, LI; Zharikov, AA | 1 |
| Leĭkina, FI; Smolianskaia, AZ | 1 |
| Andreesu, M; Matefsu, C; Mogos, I; Mudric, V | 1 |
| Berenbaum, MC; Bundick, RV; Reittie, JR; Sheard, CE | 1 |
| Carpenter, JT; Laws, HL; Maddox, WA | 1 |
| Alimov, AT; Bronshteĭn, BL; Iusupov, KN; Ostroverkhov, GE | 1 |
| Karaivanova, MK | 1 |
| Rochlin, DB; Smart, CR | 1 |
| Dendy, PP | 1 |
| Golomb, FM | 1 |
| Watt, J | 1 |
| Fetherston, WC; Grueninger, AJ; Hurley, JD; Speckhard, ME | 1 |
| Rutledge, F; Smith, JP; Wharton, JT | 1 |
| Galt, JM; Ludgate, CM; Pettigrew, RT; Smith, AN | 1 |
| Frei, E; Goldin, A; Schabel, FM | 1 |
| Chernyshev, VK; Chirkina, IuM; Li, MI; Mil'man, MSh; Shek, BA | 1 |
| Leskova, SG; Merkulov, MF | 1 |
| Leskova, S; Merkulov, M | 1 |
| Berenbaum, MC | 2 |
| Bergsagel, DE; McCulloch, EA; Ogawa, M | 2 |
| Karjalainen, J; Wasastjerna, C | 1 |
| Mohr, A; Tanneberger, S | 1 |
| Berndt, H; Rieche, K | 1 |
| Komm, SG; Larionov, LF; Shirokova, TG | 1 |
| Hall, TC; Miller, S; Nathanson, L; Schilling, A | 1 |
| Ravina, A | 1 |
| Kokame, GM; Krementz, ET | 1 |
| Burns, BC; Rutledge, F; Smith, JP; Soffar, S | 1 |
| Derriks, R; Heynen, E; Mannes, P; Moens, R | 1 |
| Edwards, AJ; Rowland, GF | 1 |
| Rutledge, F | 1 |
| Clément, F | 1 |
| Nechaeva, ID | 1 |
| Pol'kina, RI | 1 |
| Chernyĭ, VA | 2 |
| Esenkulov, AE; Nugmanov, SN | 1 |
| Iushkov, SF; Korol'chuk, VP | 2 |
| Syrkin, AB | 1 |
| Chirkina, IuM; Karimova, SB; Mil'man, MSh; Shadmankhodzhaeva, SM; Shek, BA | 1 |
| Miura, T | 1 |
| Droegemueller, W; Jones, HW; Makowski, EL | 1 |
| Fennelly, JJ | 1 |
| Edwards, AJ; Hurd, CM; Rowland, GF; Sumner, MR | 1 |
| Eridani, S; Ponti, GB; Tiso, R; Valentini, R | 1 |
| Seidel, HJ | 1 |
| Alimov, AT; Gasparian, SA | 1 |
| Abraham, D; Bowie, M; Carbone, PP; Teller, MN | 1 |
| Kumkumadzhian, VA; Papoian, SA | 1 |
| Hills, WJ; Rufino, C; Stehlin, JS | 1 |
| Fisher, B; Fisher, ER; Redmond, C | 2 |
| Chen, HS; Gross, JF | 1 |
| Dill, PL; Macaluso, CK; Marsden, JA; Weisenthal, LM | 1 |
| Hashimura, T; Hikasa, Y; Honda, K; Kern, DH; Mizuno, Y; Niwa, O; Satomura, K; Sugahara, T; Tanigawa, N; Yoshida, O | 1 |
| Bonadonna, G; Valagussa, P | 1 |
| Furnival, CM; Gough, IR | 1 |
| Pilch, YH | 1 |
| Allegra, J; Bowman, D; Brown, A; Fisher, B; Plotkin, D; Redmond, CK; Rockette, HE; Wickerham, DL; Wolter, J | 1 |
| Allegra, J; Brown, A; Escher, G; Fisher, B; Lippman, M; Redmond, C; Savlov, E; Wickerham, DL; Wittliff, J; Wolmark, N | 1 |
| Athens, JW; Costanzi, JJ; Foulkes, MA; Glucksberg, H; Knight, WA; O'Bryan, RM; Rivkin, SE; Stephens, RL | 1 |
| Caprini, JA; Cohen, E; Cunningham, MP; Grizenko, KK; Haid, M; Khandekar, JD; Oviedo, MA; Rabadi, SJ; Scanlon, EF | 1 |
| Mouridsen, HT; Palshof, T | 1 |
| Jones, SE; Moon, TE | 1 |
| Foulkes, M; Glucksberg, H; Rivkin, SE | 1 |
| Bulbrook, RD; Bush, H; Crowther, D; George, WD; Hayward, JL; Howat, JM; Howell, A; Knight, RK; Rubens, RD; Sellwood, RA | 1 |
| Smith, IE | 1 |
| Maggino, T; Onnis, A | 1 |
| Dembo, AJ | 1 |
| Ozols, RF; Young, RC | 1 |
| Davis, TE; Gilchrist, KW; Neville, AJ | 1 |
| Hill, DL; Montgomery, JA | 1 |
| Freshney, RI; Kaye, SB; Merry, S | 1 |
| Bauer, M; Brodovsky, HS; Elson, PJ; Horton, J | 1 |
| Kuroda, H; Matsumoto, K; Takeyama, M | 1 |
| Senn, HJ | 1 |
| Aguilera, J; Breau, JL; Israël, L; Lepage, E | 1 |
| Kabiev, OK; Rakhimov, KD; Vermenichev, SM | 1 |
| DeVita, VT; Henney, JE; Weiss, RB | 1 |
| Bowman, D; Brown, A; Campbell, T; Desser, R; Dimitrov, N; Elias, EG; Fisher, B; Fisher, ER; Frelick, R; Gardner, B; Geggie, P; Koontz, P; Lerner, H; LiCalzi, N; Plotkin, D; Prager, D; Redmond, C; Sachs, S; Shibata, H; Volk, H; Wittliff, J; Wolmark, N; Wolter, J | 1 |
| Cowan, K; Lippman, M | 1 |
| Aroney, RS; Dalley, DN; Levi, JA | 1 |
| Boyes, DA; Dodds, DJ; Gerulath, A; Kirk, ME; Klaassen, DJ; Levitt, M; Miller, AB; Pearson, JG; Wall, C | 1 |
| Cooper, MR; Ferree, C; Howard, V; Jackson, DV; Muss, HB; Rhyne, AL; Richards, F; Shore, A; Spurr, CL; Stuart, JJ; White, DR | 1 |
| Fisher, B; Redmond, C; Wieand, HS; Wolmark, N | 1 |
| Adams, M; James, KW; Johansen, KA; Rocker, I | 1 |
| Caprini, JA; Cohen, E; Cunningham, MP; Knox, KL; Oviedo, MA; Robinson, B; Scanlon, EF | 1 |
| Carpenter, JT; Laws, HL; Maddox, WA; Soong, SJ; Wirtschafter, DD | 1 |
| Athens, J; Costanzi, J; Gad-el-Mawla, N; Glucksberg, H; Hoogstraten, B; Maloney, T; McCracken, J; Rasmussen, S; Rivkin, SE; Tranum, B; Vaughn, C | 1 |
| Ahmann, DL; Bisel, HF; Creagan, ET; Edmonson, JH; Frytak, S; Hahn, RG; Ingle, JN; O'Fallon, JR; Payne, WS; Rubin, J; Scanlon, PW | 1 |
| Amiel, JP; Diebold, P; Dormont, D; Izrael, V; Ravina, JH; Salat-Baroux, J; Zylberberg, B | 1 |
| Creech, R; Elson, P; Gordon, P; Hahn, R; Horton, J | 1 |
| Costanza, ME | 1 |
| Gasser, RW; Schmalzl, F | 2 |
| Schmidt, JD | 1 |
| Brunner, KW; Goldhirsch, A; Joss, R; Sonntag, RW; Tschopp, L | 1 |
| Aleksandrova, GI; Dymarskiĭ, LIu; Sanchakova, AV | 1 |
| Balconi, G; D'Incalci, M; Erba, E; Garattini, S; Morasca, L; Ottolenghi, L; Salmona, A | 1 |
| Blessing, JA; Blom, J; Disaia, PJ; Lagasse, LD; Park, RC | 1 |
| Barlow, JJ; Lele, S; Piver, MS | 1 |
| Brooke, M; Bush, H; Howat, JM; Maguire, GP; Sellwood, RA; Tait, A; Thomas, C | 1 |
| Antman, K; Ayash, L; Elias, AD; Frei, E; Mazanet, R; Schnipper, L; Schwartz, G; Tepler, I; Wheeler, C | 1 |
| Berenson, R; Brown, S; Carter, C; Cottler-Fox, M; Doren, S; Dunbar, CE; Greenblatt, J; Moen, RC; O'Shaughnessy, JA; Stewart, FM | 1 |
| Dercksen, MW; Dirkson, MK; Gerritsen, WR; Pinedo, HM; Rodenhuis, S; Schaasberg, WP; Slaper-Cortenbach, IC; van der Schoot, CE; von dem Borne, AE | 1 |
| Palmer, CA; Peters, GE; Reich, DS | 1 |
| Baker, TR; Cornelison, TL; Driscoll, DL; Piver, MS | 1 |
| Sack, H | 1 |
| Dunbar, CE; Nienhuis, AW | 1 |
| Delitheos, A; Tiligada, E | 1 |
| Riley, C; Slavik, M; Wu, J | 1 |
| Bianco, AR; Carlomagno, C; De Laurentiis, M; De Placido, S; Del Mastro, L; Gallo, C; Lauria, R; Marinelli, A; Perrone, F | 1 |
| Friberg, LG; Granberg, S; Islam, MQ; Köpf, I; Levan, A; Levan, G | 1 |
| Powles, TJ; Smith, IE | 1 |
| Ben-Efraim, S; Burstein, Y; Keisari, Y; Lourie, S; Meshorer, A; Ophir, R; Pecht, M; Rashid, G; Trainin, N | 2 |
| Abu-Abid, S; Chaitchik, S; Chen, Z; Gutman, M; Inbar, M; Klausner, JM; Lev, D; Oron, D; Sorkine, P | 1 |
| Gaarsdal, E; Jensen, L; Johnsen, HE; Knudsen, LM; Nielsen, KJ; Nikolaisen, K | 1 |
| Del Mastro, L; Rosso, R; Sertoli, MR; Venturini, M | 1 |
| Ben-Ari, GY | 1 |
| Dreger, P; Glass, B; Kuse, R; Löffler, H; Schmitz, N; Schoch, R; Sonnen, R; Uharek, L; von Neuhoff, N | 1 |
| Aebi, S; Fink, D; Fink, JL; Gordon, R; Howell, SB; Kim, HK; Zheng, H | 1 |
| Ettenberg, SA; Keane, MM; Lipkowitz, S; Nau, MM; Russell, EK | 1 |
| Benoit, L; Chauffert, B; Duvillard, C; L'Helgouarc'h, JL | 1 |
| Berry, DA; Cirrincione, C; Costanza, ME; Frei, E; Henderson, IC; McIntyre, OR; Norton, L; Schilsky, RL; Weiss, RB; Winer, E; Wood, WC | 1 |
| Danenberg, PV; Kornmann, M; Leder, GH; Link, KH; Pillasch, J | 1 |
| Ben-Ari, G; Koller, M; Papa, M; Sareli, M; Scott, D; Zippel, D | 1 |
| Beger, HG; Gansauge, F; Gansauge, S; Nussler, AK; Schlosser, S; Schnelldorfer, T | 1 |
| Katai, H; Saka, M; Sano, T; Sasako, M | 1 |
| de Boer, F; Dräger, AM; Huijgens, PC; Kessler, F; Pinedo, HM; Schuurhuis, GJ; van der Wall, E; Van Haperen, MJ | 1 |
| Adjei, AA; Bruzek, LM; Davis, JN; Erlichman, C; Kaufmann, SH | 1 |
| Bloomer, WD; Ji, M; Papadopoulou, MV | 1 |
| Chatzissavvidis, I; Müller, H; Nakchbandi, W; Valek, V | 1 |
| Avigan, D; Elias, AD; Frei, E; Ibrahim, J; Joyce, R; McCauley, M; Reich, E; Richardson, P; Wheeler, C | 1 |
| Athens, JW; Costanzi, JJ; Green, SJ; Lew, D; Martino, S; Osborne, CK; Rivkin, SE; Vaughn, CB | 1 |
| Allen, TM; Balzarini, J; De Clercq, E; Dimmock, JR; Manavathu, EK; Nienaber, KH; Padmanilayam, MP; Santos, CL; Stables, JP; Zello, GA | 1 |
| KUKRAL, JC; PRESTON, FW; STALEY, CJ | 1 |
| CHIRIGOS, MA; FANNING, GR; GOLDIN, A; KAMEL, IA; RAUSCHER, FJ | 1 |
| CAGLI, V | 1 |
| IGLESIAS, F; KOKAME, GM; KREMENTZ, ET | 1 |
| KNOCK, FE | 1 |
| CHIRIGOS, MA; GLYNN, JP; GOLDIN, A; HUMPHREYS, SR; MOLONEY, JB | 1 |
| MAIJNELLI, M; PERITI, P | 1 |
| GARATTINI, S; PALMA, V; REYERS-DEGLIINNOCENTI, I | 1 |
| Asada, Y; Fujisawa, K; Iida, Y; Kasahara, Y; Mitsui, T; Miura, S; Munemoto, Y; Ohata, K; Saito, H | 1 |
| de Wilt, JH; Eggermont, AM; van Etten, B; Verhoef, C | 1 |
| Anderson, S; Bryant, J; Deutsch, M; Jeong, JH; Mamounas, E; Taghian, A; Wolmark, N | 1 |
| Brody, JR; Cunningham, SC; DeMarzo, AM; Dezentje, DA; Gallmeier, E; Hruban, RH; Isacoff, WH; Kern, SE; Offerhaus, GJ; Swartz, MJ; van der Heijden, MS | 1 |
| Bremer, M; Karstens, JH; Meier Zu Eissen, J; Meyer, A | 1 |
| Glimelius, B; Graf, W; Grundmark, B; Larsson, R; Mahteme, H; Nygren, P; Påhlman, L; Tholander, B; von Heideman, A | 1 |
| Gutweiler, JR; Kim, HB; Kozakewich, HP; Marcus, KJ; Shamberger, RC; Weldon, CB; Yu, DC | 1 |
| Dalenc, F; Filleron, T; Fumoleau, P; Kerbrat, P; Kramar, A; Martin, AL; Roché, H; Spielmann, M | 1 |
| Hatano, T; Orabi, MA; Sakagami, H; Taniguchi, S; Yoshida, T; Yoshimura, M | 1 |
| Angelini, V; Arcadipane, F; Bombaci, S; Cassoni, P; Franco, P; Migliaccio, F; Mistrangelo, M; Morino, M; Munoz, F; Numico, G; Racca, P; Ragona, R; Ricardi, U; Rondi, N; Sciacero, P; Spadi, R | 1 |
| Clarkson, JE; Glenny, AM; Littlewood, A; McCabe, MG; Riley, P; Worthington, HV | 1 |
| Wodzinski, A | 1 |
| Belmont-Díaz, JA; Cruz-Muñiz, MY; Franco-Cendejas, R; García-Contreras, R; Hernández-Durán, M; Licona-Limón, P; López-Jacome, LE; Martinéz-Vázquez, M; Ramos-Balderas, JL; Wood, TK | 1 |
| Bogner, S; Peis, MW; Reinboldt, MP; Schuler, M; Tewes, M; Theysohn, JM; Welt, A | 1 |
| Paul, R; Paul, S | 1 |
40 review(s) available for fluorouracil and melphalan
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Chemotherapy of solid tumors. Recent advances.
Topics: Adult; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Child; Cyclophosphamide; Doxorubicin; Drug Combinations; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunotherapy; Leucovorin; Male; Melphalan; Methotrexate; Neoplasm Metastasis; Neoplasms; Osteosarcoma; Prednisone; Rhabdomyosarcoma; Testicular Neoplasms; Thiotepa; Vinblastine; Vincristine | 1976 |
[Adjuvant (preventive) postoperative chemotherapy in breast carcinoma].
Topics: Breast Neoplasms; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; Humans; Melphalan; Menopause; Methotrexate; Postoperative Care | 1978 |
The treatment of plasma cell myeloma.
Topics: Animals; Carmustine; Cytarabine; Doxorubicin; Drug Evaluation, Preclinical; Fluorouracil; Humans; Melphalan; Methotrexate; Mice; Mice, Inbred BALB C; Multiple Myeloma; Myeloma Proteins; Prednisone; Procarbazine; Remission, Spontaneous | 1976 |
The role of chemotherapy in the treatment of cancer of the breast.
Topics: Breast Neoplasms; Castration; Cyclophosphamide; Drug Resistance; Estrogens; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Prednisone; Thiotepa | 1975 |
Hypersensitivity reactions.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Aziridines; Benzoquinones; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide; Cytarabine; Dacarbazine; Drug Hypersensitivity; Etoposide; Fluorouracil; Humans; Ifosfamide; Melphalan; Methotrexate; Mitomycins; Neoplasms; Paclitaxel; Pentostatin; Procarbazine; Teniposide | 1992 |
Cytotoxic treatment of metastatic breast cancer. Which drugs and drug combinations to use?
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Epirubicin; Etoposide; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Mitomycin; Mitoxantrone; Neoplasm Metastasis; Vincristine | 1992 |
Adjuvant therapy in breast cancer.
Topics: Adjuvants, Pharmaceutic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Prednisone; Tamoxifen; Vincristine | 1990 |
Drug level monitoring: cytostatics.
Topics: Alkylating Agents; Aminoacridines; Amsacrine; Anthraquinones; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Bleomycin; Busulfan; Chlorambucil; Chromatography, Gas; Chromatography, Liquid; Cisplatin; Cyclophosphamide; Cytarabine; Fluorouracil; Humans; Mass Spectrometry; Melphalan; Methotrexate; Mitomycins; Monitoring, Physiologic; Nitrosourea Compounds; Podophyllotoxin; Purines; Thiotepa; Vinca Alkaloids | 1985 |
Intracavitary chemotherapy.
Topics: Absorption; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Bacterial Infections; Bleomycin; Cisplatin; Cytarabine; Diffusion; Doxorubicin; Drug Synergism; Female; Fluorouracil; Humans; Immunotherapy; Melphalan; Methotrexate; Mitomycins; Neoplasms; Ovarian Neoplasms; Peritoneal Cavity; Permeability; Pleura; Pleural Effusion; Radiation-Sensitizing Agents; Sclerosis; Streptozocin | 1985 |
Corticosteroid drugs: their role in oncological practice.
Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms; Cyclophosphamide; Dacarbazine; Doxorubicin; Drug Therapy, Combination; Dyspnea; Fluorouracil; Hodgkin Disease; Humans; Hypercalcemia; Leukemia; Leukemia, Lymphoid; Lymphoma; Mechlorethamine; Melphalan; Methotrexate; Multiple Myeloma; Palliative Care; Prednisone; Procarbazine; Receptors, Glucocorticoid; Vinblastine; Vincristine; Vomiting | 1986 |
Effects of estrogens and antiestrogens on cell proliferation: implications for the treatment of breast cancer.
Topics: Animals; Breast Neoplasms; Cell Cycle; Cell Division; Estrogen Antagonists; Estrogens; Fluorouracil; Humans; In Vitro Techniques; Melphalan; Mice; Tamoxifen | 1988 |
[Chemotherapy of prostatic cancer].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dacarbazine; Diethylstilbestrol; Doxorubicin; Estramustine; Fluorouracil; Humans; Hydroxyurea; Male; Melphalan; Methotrexate; Mitomycin; Mitomycins; Prednisolone; Procarbazine; Prostatic Neoplasms; Streptozocin; Vincristine | 1985 |
Prednimustine in advanced breast cancer: a review.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Leukocyte Count; Melphalan; Methotrexate; Prednimustine; Time Factors | 1986 |
Intraperitoneal chemotherapy: a review.
Topics: Abdominal Neoplasms; Antineoplastic Agents; Cisplatin; Clinical Trials as Topic; Cytarabine; Doxorubicin; Evaluation Studies as Topic; Fluorouracil; Humans; Injections, Intraperitoneal; Liver; Mathematics; Melphalan; Methotrexate; Peritoneum | 1986 |
Adjuvant therapy in primary breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Hospitalization; Humans; Lymph Nodes; Melphalan; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Random Allocation; Tamoxifen; Time Factors; United States; Vincristine | 1985 |
[Chemotherapy of cancer of the large intestine].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colonic Neoplasms; Drug Evaluation; Fluorouracil; Humans; Lomustine; Melphalan; Methotrexate; Rectal Neoplasms; Semustine; Vincristine | 1985 |
Breast cancer chemotherapy: perioperative considerations in breast reconstruction.
Topics: Adult; Alkylating Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Mastectomy; Melphalan; Methotrexate; Middle Aged; Prednisone; Surgery, Plastic; Tamoxifen; Thiotepa; Vincristine | 1985 |
[Principles of the effect of cytostatics].
Topics: Antineoplastic Agents; Asparaginase; Cell Division; Chlorambucil; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Fluorouracil; Folic Acid Antagonists; Humans; Melphalan; Mercaptopurine; Methotrexate; Neoplasms; Triaziquone; Triethylenephosphoramide; Vincristine | 1974 |
The chemical therapy of breast cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Castration; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Nitrogen Mustard Compounds; Prednisone; Thiotepa; Vinblastine; Vincristine | 1974 |
The use of cytotoxic drugs in the surgery of malignant disease.
Topics: Abdominal Neoplasms; Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Carcinoma, Basal Cell; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Dysgerminoma; Female; Fluorouracil; Head; Head and Neck Neoplasms; Hodgkin Disease; Humans; Injections, Intra-Arterial; Leg; Melanoma; Melphalan; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasms; Nitrogen Mustard Compounds; Pregnancy; Sarcoma; Sarcoma, Ewing; Skin Neoplasms; Vinblastine; Wilms Tumor | 1968 |
An assessment of massive-dose chemotherapy of malignant disease.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cell Division; Cyclophosphamide; Cytarabine; Female; Fluorouracil; Humans; Leukemia L1210; Leukemia, Lymphoid; Lymphoma; Melphalan; Mercaptopurine; Methotrexate; Mice; Multiple Myeloma; Neoplasms; Nitrogen Mustard Compounds; Prednisone; Pregnancy; Time Factors; Trophoblastic Neoplasms; Vinblastine | 1971 |
Single and combination nonhormonal chemotherapy in breast cancer.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Drug Synergism; Female; Fluorouracil; Humans; Hydroxyurea; Melphalan; Menopause; Methotrexate; Mice; Vinblastine; Vincristine | 1972 |
[Burkitt's lymphoma and acute leukemias].
Topics: Acute Disease; Animals; Asparaginase; Burkitt Lymphoma; Child; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Fluorouracil; Humans; Leukemia; Melphalan; Mercaptopurine; Methotrexate; Mice; Oncogenic Viruses; Prednisolone; Prednisone; Vincristine | 1969 |
Chemotherapy of ovarian cancer with melphalan.
Topics: Adenocarcinoma; Ascites; Carcinoma; Cyclophosphamide; Female; Fluorouracil; Humans; Injections, Intravenous; Melphalan; Nitrogen Mustard Compounds; Ovarian Neoplasms; Thiotepa | 1968 |
[Current status of chemotherapy of malignant tumors of the ovaries].
Topics: Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Ovarian Neoplasms; Thiotepa; Triaziquone; Vinblastine | 1968 |
Chemotherapy of breast cancer: current views and results.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Prognosis; Receptors, Estrogen; Research Design | 1983 |
Adjuvant systemic therapy in primary breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Castration; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Fluorouracil; Humans; Mastectomy; Melphalan; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Random Allocation; Receptors, Estrogen; Tamoxifen; Time Factors | 1984 |
Adjuvant chemotherapy for early breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasm Metastasis; Time Factors | 1983 |
Radiotherapeutic management of ovarian cancer.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukemia; Melphalan; Ovarian Neoplasms | 1984 |
Chemotherapy of ovarian cancer.
Topics: Altretamine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Estrogen Antagonists; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Ovarian Neoplasms; Progestins; Tamoxifen | 1984 |
Selective uptake and retention of anticancer agents by sensitive cells.
Topics: Animals; Antineoplastic Agents; Cytarabine; Doxorubicin; Floxuridine; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasms | 1980 |
Advances in the multimodal primary management of cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Osteosarcoma | 1980 |
Recent progress in breast cancer management. Combined modality (adjuvant) therapy.
Topics: Adult; Animals; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Mammary Neoplasms, Experimental; Melphalan; Methotrexate; Middle Aged; Prednisone; Vincristine | 1981 |
Amenorrhea induced by adjuvant chemotherapy in early breast cancer patients: prognostic role and clinical implications.
Topics: Amenorrhea; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Fluoxymesterone; Humans; Melphalan; Methotrexate; Premenopause; Prognosis; Thiotepa; Vinblastine | 1997 |
[Current status and problem of adjuvant chemotherapy for curatively resected gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Melphalan; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Semustine; Stomach Neoplasms; Tegafur; Uracil | 2000 |
NEWER ANTICANCER AGENTS.
Topics: Alkylating Agents; Antineoplastic Agents; Arsenicals; Cyclophosphamide; Dactinomycin; Fluorouracil; Humans; Mechlorethamine; Melphalan; Methotrexate; Mitomycin; Mitomycins; Neoplasms; Pharmacology; Steroids; Triethylenemelamine; Vinblastine; Vincristine | 1964 |
[CHEMOTHERAPY OF UTERINE CERVIX CARCINOMA].
Topics: Antineoplastic Agents; Azaguanine; Aziridines; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Fluorouracil; Humans; Infusions, Parenteral; Melphalan; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Triaziquone; Uracil Mustard; Uterine Cervical Neoplasms; Vinblastine | 1964 |
Isolated hepatic perfusion: experimental evidence and clinical utility.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Hepatic Artery; Humans; Liver Neoplasms; Melphalan; Tumor Necrosis Factor-alpha | 2004 |
Interventions for preventing oral mucositis in patients with cancer receiving treatment: oral cryotherapy.
Topics: Adult; Antineoplastic Agents; Cryotherapy; Fluorouracil; Hematopoietic Stem Cell Transplantation; Humans; Melphalan; Mouth Diseases; Myeloablative Agonists; Neoplasms; Pain; Randomized Controlled Trials as Topic; Stomatitis | 2015 |
100 trial(s) available for fluorouracil and melphalan
| Article | Year |
|---|---|
Repeated adjuvant chemotherapy with phenylalanine mustard or 5-fluorouracil, cyclophosphamide, and prednisone with or without radiation, after mastectomy for breast cancer.
Topics: Adult; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Melphalan; Middle Aged; Neoplasm Recurrence, Local; Postoperative Care; Prednisone; Remission, Spontaneous; Time Factors | 1978 |
Advanced ovarian adenocarcinoma. A prospective clinical trial of melphalan (L-PAM) versus combination chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Altretamine; Antineoplastic Agents; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Ovarian Neoplasms; Prospective Studies | 1978 |
Hexa-CAF combination chemotherapy and other multiple-drug regimens in advanced ovarian carcinoma: present and future.
Topics: Altretamine; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Melphalan; Middle Aged; Ovarian Neoplasms; Triazines | 1979 |
Histologic grade in advanced ovarian cancer.
Topics: Altretamine; Cell Differentiation; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Ovarian Neoplasms; Prognosis | 1979 |
Advances in the staging and treatment of ovarian cancer.
Topics: Alkylating Agents; Altretamine; Antimetabolites, Antineoplastic; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Laparoscopy; Lymphatic Metastasis; Lymphography; Melphalan; Neoplasm Metastasis; Ovarian Neoplasms | 1977 |
L-phenylalanine mustard (L-PAM) in the management of primary breast cancer. An update of earlier findings and a comparison with those utilizing L-PAM plus 5-fluorouracil (5-FU).
Topics: Adenocarcinoma, Mucinous; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukopenia; Lymphatic Metastasis; Mastectomy; Melphalan; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prospective Studies; Thrombocytopenia | 1977 |
Chemotherapy of disseminated breast cancer. Current status and prospects.
Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Estrogens, Conjugated (USP); Female; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasm Metastasis; Prednisone; Vincristine | 1977 |
Adjuvant chemotherapy in the primary management of breast cancer.
Topics: Adult; Aged; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Survival; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Recurrence; Research Design | 1977 |
Randomized trial of melphalan plus 5-fluorouracil (5-FU) versus methyl-CCNU plus 5-FU in patients with advanced colorectal cancer.
Topics: Adult; Aged; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Melphalan; Middle Aged; Nitrosourea Compounds; Rectal Neoplasms; Semustine | 1978 |
Phase II trial of 5-fluorouracil plus melphalan in colorectal carcinoma.
Topics: Adenocarcinoma; Clinical Trials as Topic; Colonic Neoplasms; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Melphalan; Middle Aged; Rectal Neoplasms | 1978 |
[Chemotherapy in curable breast cancer].
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged | 1978 |
Preliminary report of a clinical trial of the treatment of patients with advanced stage III and IV ovarian cancer with melphalan, 5-fluorouracil, and methotrexate in combination and sequentially: a study of the Clinical Trials Group of the National Cancer
Topics: Adult; Aged; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Ovarian Neoplasms; Remission, Spontaneous; Time Factors | 1979 |
Controlled prospective trial of combination chemotherapy with cyclophosphamide, adriamycin, and 5-fluorouracil for the treatment of advanced ovarian cancer: a preliminary report.
Topics: Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Organothiophosphorus Compounds; Ovarian Neoplasms; Remission, Spontaneous | 1979 |
Levamisole: as adjuvant to cyclic chemotherapy in breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Levamisole; Melphalan; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis | 1978 |
The dilemma regarding postoperative chemotherapy in primary carcinoma of the colon.
Topics: Antineoplastic Agents; BCG Vaccine; Breast Neoplasms; Carcinoma; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Mycobacterium bovis; Neoplasm Metastasis; Postoperative Care; Semustine; Vincristine | 1979 |
Second trial drugs in ovarian cancer.
Topics: Altretamine; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Ovarian Neoplasms; Thiotepa | 1977 |
Ovarian cancer: use of multiple modality programs involving surgery, radiation therapy and chemotherapy.
Topics: Altretamine; Antineoplastic Agents; Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunotherapy; Melphalan; Ovarian Neoplasms; Propionibacterium acnes; Radiotherapy Dosage | 1977 |
Chemotherapy in ovarian carcinoma recurrent after radiation therapy.
Topics: Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Middle Aged; Neoplasm Recurrence, Local; New York; Ovarian Neoplasms; Prospective Studies; Quality of Life; Thrombocytopenia | 1978 |
Randomized comparison of melphalan and 5-fluorouracil in the treatment of advanced gastrointestinal cancer.
Topics: Adult; Aged; Biliary Tract Diseases; Clinical Trials as Topic; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Melphalan; Middle Aged; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms | 1976 |
Preliminary Results of trials of chemotherapy in advanced ovarian carcinoma.
Topics: Altretamine; Antineoplastic Agents; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Maryland; Melphalan; Methotrexate; National Institutes of Health (U.S.); Ovarian Neoplasms; Prospective Studies; United States | 1975 |
Random study of hexamethylmelamine, 5-fluorouracil, and melphalan in treatment of advanced carcinoma of the ovary.
Topics: Adult; Altretamine; Antineoplastic Agents; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Ovarian Neoplasms | 1975 |
Primary treatment of advanced ovarian adenocarcinoma, stages III and IV.
Topics: Adenocarcinoma; Alkylating Agents; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Ovarian Neoplasms; Thiotepa | 1975 |
Single agent vs combination chemotherapy in the treatment of ovarian cancer.
Topics: Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Ovarian Neoplasms | 1977 |
Combination chemotherapy for metastatic breast carcinoma. Prospective comparison of multiple drug therapy with L-phenylalanine mustard.
Topics: Adult; Aged; Antineoplastic Agents; Boston; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Prospective Studies | 1976 |
Advances in chemotherapy for gynecologic cancer.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Middle Aged; Ovarian Neoplasms; Pelvic Neoplasms; Sarcoma; Teratoma; Vincristine | 1975 |
NSABP trials of adjuvant chemotherapy for breast cancer. A further look at the evidence.
Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Menopause; Middle Aged; Neoplasm Staging; Survival Rate | 1991 |
A randomized trial of chemotherapy (L-PAM vs CMF) and irradiation for node positive breast cancer. Eleven year follow-up of a Piedmont Oncology Association trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Lymphatic Metastasis; Melphalan; Methotrexate; Middle Aged; Survival Rate | 1991 |
Adjuvant therapy in breast cancer.
Topics: Adjuvants, Pharmaceutic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Prednisone; Tamoxifen; Vincristine | 1990 |
Postoperative chemotherapy and tamoxifen compared with tamoxifen alone in the treatment of positive-node breast cancer patients aged 50 years and older with tumors responsive to tamoxifen: results from the National Surgical Adjuvant Breast and Bowel Proje
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Estrogens; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Middle Aged; Multicenter Studies as Topic; Neoplasms, Hormone-Dependent; Randomized Controlled Trials as Topic; Tamoxifen | 1990 |
Evaluation of the worth of corynebacterium parvum in conjunction with chemotherapy as adjuvant treatment for primary breast cancer. Eight-year results from the National Surgical Adjuvant Breast and Bowel Project B-10.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bacterial Vaccines; Breast Neoplasms; Combined Modality Therapy; Drug Evaluation; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Middle Aged; Patient Compliance; Prognosis; Propionibacterium acnes; Randomized Controlled Trials as Topic; Survival Analysis | 1990 |
Intracavitary chemotherapy.
Topics: Anthraquinones; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Catheters, Indwelling; Cisplatin; Clinical Trials as Topic; Cytarabine; Doxorubicin; Etoposide; Fluorouracil; Humans; Immunotherapy; Infusions, Parenteral; Melphalan; Methotrexate; Mitomycins; Mitoxantrone; Neoplasms; Organoplatinum Compounds | 1986 |
Doxorubicin-containing regimens for the treatment of stage II breast cancer: The National Surgical Adjuvant Breast and Bowel Project experience.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Protocols; Clinical Trials as Topic; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Melphalan; Middle Aged; Random Allocation; Tamoxifen | 1989 |
Adjuvant CMFVP versus melphalan for operable breast cancer with positive axillary nodes: 10-year results of a Southwest Oncology Group Study.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy, Modified Radical; Mastectomy, Radical; Melphalan; Methotrexate; Prednisone; Vincristine | 1989 |
Adjuvant chemotherapy in stage II breast cancer: a brief overview of the NSABP clinical trials.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Staging; Random Allocation | 1985 |
Adjuvant chemotherapy with and without tamoxifen in the treatment of primary breast cancer: 5-year results from the National Surgical Adjuvant Breast and Bowel Project Trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Melphalan; Middle Aged; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1986 |
Comparison of different trials of adjuvant chemotherapy in stage II breast cancer using a natural history data base.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Information Systems; Lymphatic Metastasis; Medical Records; Melphalan; Methotrexate; Middle Aged; Postoperative Care; Prednisone; Random Allocation; Time Factors; Vincristine | 1987 |
Prednimustine in advanced breast cancer: a review.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Leukocyte Count; Melphalan; Methotrexate; Prednimustine; Time Factors | 1986 |
Intraperitoneal chemotherapy: a review.
Topics: Abdominal Neoplasms; Antineoplastic Agents; Cisplatin; Clinical Trials as Topic; Cytarabine; Doxorubicin; Evaluation Studies as Topic; Fluorouracil; Humans; Injections, Intraperitoneal; Liver; Mathematics; Melphalan; Methotrexate; Peritoneum | 1986 |
Adjuvant therapy for breast cancer: a brief overview of the NSABP experience and some thoughts on neoadjuvant chemotherapy.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Methotrexate; Middle Aged; Receptors, Estrogen; Tamoxifen | 1986 |
Systemic adjuvant therapy in treatment of primary operable breast cancer: National Surgical Adjuvant Breast and Bowel Project experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Mastectomy; Melphalan; Methotrexate; Middle Aged; Tamoxifen | 1986 |
Adjuvant therapy of breast cancer: Southwest Oncology Group studies.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Melphalan; Methotrexate; Middle Aged; Prednisone; Vincristine | 1986 |
Value of cyclophosphamide or melphalan as combined chemotherapy in hormonally unresponsive prostatic carcinoma.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Fluorouracil; Humans; Male; Melphalan; Methotrexate; Prednisone; Prostatic Neoplasms; Random Allocation; Vincristine | 1986 |
Prolonging tamoxifen therapy for primary breast cancer. Findings from the National Surgical Adjuvant Breast and Bowel Project clinical trial.
Topics: Actuarial Analysis; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Humans; Melphalan; Middle Aged; Random Allocation; Tamoxifen | 1987 |
Adjuvant chemotherapy for operable breast cancer with positive axillary nodes: a comparison of CMFVP versus L-PAM.
Topics: Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lymph Nodes; Melphalan; Methotrexate; Prednisone; Vincristine | 1985 |
Adjuvant chemotherapy for breast cancer. Implications of clinical trials.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Melphalan; Menopause; Methotrexate; Neoplasm Metastasis; Prednisone; Random Allocation; Vincristine | 1985 |
Adjuvant chemotherapy of breast cancer: a promising experiment or standard practice?
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Menopause; Methotrexate; Prednisone; Prognosis; Tamoxifen; Vincristine | 1985 |
A randomized controlled trial of prophylactic cytotoxic chemotherapy in potentially curable breast cancer.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Humans; Melphalan; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Patient Compliance; Random Allocation | 1985 |
Adjuvant tamoxifen and chemotherapy in stage II breast cancer: interim findings from NSABP protocol B-09.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Female; Fluorouracil; Humans; Melphalan; Middle Aged; Neoplasm Staging; Prospective Studies; Random Allocation; Tamoxifen | 1985 |
A randomized comparison of cyclophosphamide, Adriamycin, and 5-fluorouracil with triethylenethiophosphoramide and methotrexate, both as sequential and as fixed rotational treatment in patients with advanced ovarian cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Ovarian Neoplasms; Prospective Studies; Random Allocation; Thiotepa | 1985 |
Breast cancer chemotherapy: perioperative considerations in breast reconstruction.
Topics: Adult; Alkylating Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Mastectomy; Melphalan; Methotrexate; Middle Aged; Prednisone; Surgery, Plastic; Tamoxifen; Thiotepa; Vincristine | 1985 |
[Results of the Hamburg ovarian blastoma study].
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Germany, West; Humans; Ifosfamide; Melphalan; Methotrexate; Neoplasm Staging; Ovarian Neoplasms; Prognosis; Random Allocation; Tegafur; Vincristine | 1985 |
Melphalan, 5-fluorouracil, and medroxyprogesterone acetate in metastatic endometrial carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Female; Fluorouracil; Humans; Medroxyprogesterone; Melphalan; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prospective Studies; Random Allocation; Tamoxifen; Thrombocytopenia; Uterine Neoplasms | 1986 |
Clinical effects of whole-body hyperthermia in adnanced malignancy.
Topics: Adult; Body Temperature; Breast Neoplasms; Child; Colonic Neoplasms; Cyclophosphamide; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Hyperthermia, Induced; Injections, Intravenous; Male; Melphalan; Neoplasms; Time Factors; Vincristine | 1974 |
Concurrent combination chemotherapy of human solid tumors: experience with a three-drug regimen and review of the literature.
Topics: Adolescent; Adult; Aged; Bone Marrow; Bone Neoplasms; Carcinoma; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Drug Synergism; Female; Fluorouracil; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Melanoma; Melphalan; Middle Aged; Mitomycins; Parotid Neoplasms; Sarcoma; Urogenital Neoplasms; Vincristine | 1969 |
A brief overview of findings from NSABP trials of adjuvant therapy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Humans; Mastectomy; Melphalan; Methotrexate; Prognosis; Tamoxifen | 1984 |
Chemotherapy of breast cancer: current views and results.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Prognosis; Receptors, Estrogen; Research Design | 1983 |
High-dose intermittent iv 5-FU and melphalan in advanced colorectal carcinoma.
Topics: Adult; Aged; Clinical Trials as Topic; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluorouracil; Humans; Infusions, Parenteral; Male; Melphalan; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms | 1983 |
Breast cancer treatment--current status. 2. Segmental mastectomy, alternative to total breast excision?
Topics: Breast Neoplasms; Clinical Trials as Topic; Female; Fluorouracil; Humans; Lymph Node Excision; Mastectomy; Melphalan; Postoperative Care; Prospective Studies; Radiotherapy Dosage; Random Allocation | 1983 |
Relation of estrogen and/or progesterone receptor content of breast cancer to patient outcome following adjuvant chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Female; Fluorouracil; Humans; Lymph Nodes; Melphalan; Neoplasm Recurrence, Local; Receptors, Estrogen; Receptors, Progesterone; Risk; Tamoxifen | 1983 |
Influence of tumor estrogen and progesterone receptor levels on the response to tamoxifen and chemotherapy in primary breast cancer.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Female; Fluorouracil; Humans; Lymph Nodes; Melphalan; Middle Aged; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Statistics as Topic; Tamoxifen | 1983 |
Adjuvant chemotherapy in stage-II breast cancer: an overview of the NSABP clinical trials.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Methotrexate; Middle Aged | 1983 |
Adjuvant therapy of breast cancer: the Southwest Oncology Group experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Menopause; Methotrexate; Prednisone; Vincristine | 1983 |
Multiple trials of adjuvant chemohormonal therapy in the treatment of breast cancer: preliminary results--the ECOG experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Menopause; Methotrexate; Prednisone; Tamoxifen | 1983 |
Treatment of primary breast cancer with L-PAM/5-FU and tamoxifen: an interim report.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Middle Aged; Receptors, Estrogen; Tamoxifen | 1983 |
Treatment of breast carcinoma recurrent after adjuvant chemoimmunotherapy.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prednisolone; Prospective Studies; Random Allocation | 1984 |
Adjuvant systemic therapy in primary breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Castration; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Fluorouracil; Humans; Mastectomy; Melphalan; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Random Allocation; Receptors, Estrogen; Tamoxifen; Time Factors | 1984 |
The use of a natural history data base to compare outcome among several trials of adjuvant chemotherapy for stage II breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Methotrexate; Neoplasm Staging; Prednisone; Prognosis; Vincristine | 1984 |
Adjuvant therapy of breast cancer: a Southwest Oncology Group experience.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Menopause; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Prognosis; Vincristine | 1984 |
A controlled trial of adjuvant chemotherapy with melphalan versus cyclophosphamide, methotrexate, and fluorouracil for breast cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis | 1984 |
Adjuvant chemotherapy for early breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasm Metastasis; Time Factors | 1983 |
Radiotherapeutic management of ovarian cancer.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukemia; Melphalan; Ovarian Neoplasms | 1984 |
Adjuvant chemotherapy for breast cancer.
Topics: Age Factors; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Menopause; Middle Aged; Prognosis; Thiotepa | 1981 |
Adjuvant chemotherapy of breast cancer.
Topics: Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Melphalan; Menopause; Methotrexate | 1981 |
Advances in the multimodal primary management of cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Osteosarcoma | 1980 |
Treatment of primary breast cancer with chemotherapy and tamoxifen.
Topics: Age Factors; Breast Neoplasms; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Melphalan; Middle Aged; Random Allocation; Receptors, Estrogen; Tamoxifen | 1981 |
Recent progress in breast cancer management. Combined modality (adjuvant) therapy.
Topics: Adult; Animals; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Mammary Neoplasms, Experimental; Melphalan; Methotrexate; Middle Aged; Prednisone; Vincristine | 1981 |
Triple drug chemotherapy for advanced ovarian carcinoma: comparative study of two regimens.
Topics: Antineoplastic Agents; Bone Marrow Diseases; Carcinoma; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukemia; Melphalan; Ovarian Neoplasms | 1981 |
Combination v. sequential therapy with melphalan, 5-fluorouracil and methotrexate for advanced ovarian cancer.
Topics: Adult; Aged; Antineoplastic Agents; Canada; Carcinoma; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Ovarian Neoplasms | 1980 |
A randomized comparative trial of chemotherapy and irradiation therapy for stage II breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Postoperative Care; Prospective Studies; Radiotherapy Dosage; Random Allocation | 1981 |
Disease-free survival at intervals during and following completion of adjuvant chemotherapy: the NSABP experience from three breast cancer protocols.
Topics: Age Factors; Aged; Breast Neoplasms; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymph Nodes; Melphalan; Methotrexate; Middle Aged; Prognosis | 1981 |
The current status of systemic adjuvant therapy in the management of primary breast cancer.
Topics: Age Factors; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Probability; Random Allocation; Tamoxifen | 1981 |
A controlled clinical trial in advanced ovarian cancer.
Topics: Antineoplastic Agents; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Middle Aged; Ovarian Neoplasms; Random Allocation | 1982 |
Follow-up adjuvant chemotherapy and chemoimmunotherapy for stage II and III carcinoma of the breast.
Topics: Antineoplastic Agents; BCG Vaccine; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Melphalan; Neoplasm Recurrence, Local; Prednisone; Prognosis; Prospective Studies | 1982 |
Favorable factors in the adjuvant therapy of breast cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 1982 |
Combination chemotherapy (CMFVP) versus L-phenylalanine mustard (L-PAM) for operable breast cancer with positive axillary nodes: a Southwest Oncology Group Study.
Topics: Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Menopause; Methotrexate; Prednisone; Vincristine | 1982 |
A preliminary assessment of factors associated with recurrent disease in a surgical adjuvant clinical trial for patients with breast cancer with special emphasis on the aggressiveness of therapy.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukocyte Count; Leukopenia; Mastectomy; Melphalan; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Prognosis; Random Allocation; Thrombocytopenia | 1982 |
Treatment of women with disseminated or recurrent advanced ovarian cancer with melphalan alone in combination with 5-fluorouracil and dactinomycin or with the combination of cytoxan, 5-fluorouracil and dactinomycin.
Topics: Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Erythrocyte Count; Female; Fluorouracil; Humans; Melphalan; Neoplasm Metastasis; Neoplasm Recurrence, Local; Ovarian Neoplasms; Platelet Count; Prognosis; Time Factors | 1980 |
Psychiatric morbidity and physical toxicity associated with adjuvant chemotherapy after mastectomy.
Topics: Affective Symptoms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Libido; Mastectomy; Melphalan; Methotrexate | 1980 |
The use of G-CSF or GM-CSF mobilized peripheral blood progenitor cells (PBPC) alone or to augment marrow as hematologic support of single or multiple cycle high-dose chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Bone Marrow Transplantation; Breast Neoplasms; Carboplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Graft Survival; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Leukapheresis; Male; Melphalan; Methotrexate; Middle Aged; Neoplasms; Neutropenia; Salvage Therapy; Treatment Outcome | 1993 |
Retrovirally marked CD34-enriched peripheral blood and bone marrow cells contribute to long-term engraftment after autologous transplantation.
Topics: Antigens, CD; Antigens, CD34; Bone Marrow Transplantation; Breast Neoplasms; Cyclophosphamide; Female; Filgrastim; Fluorouracil; Follow-Up Studies; Genes, Reporter; Genetic Markers; Genetic Therapy; Graft Survival; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Kanamycin Kinase; Male; Melphalan; Middle Aged; Multiple Myeloma; Phosphotransferases (Alcohol Group Acceptor); Recombinant Proteins; Treatment Outcome; Whole-Body Irradiation | 1995 |
Cisplatin, adriamycin, etoposide, megestrol acetate versus melphalan, 5-fluorouracil, medroxyprogesterone acetate in the treatment of endometrial carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Endometrial Neoplasms; Etoposide; Female; Fluorouracil; Humans; Medroxyprogesterone Acetate; Megestrol; Megestrol Acetate; Melphalan; Middle Aged; Prospective Studies; Survival Rate | 1995 |
Endocrine factors in the outcome of systemic adjuvant therapy of early breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Ovariectomy; Postmenopause; Premenopause; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Survival Rate; Tamoxifen; Treatment Outcome | 1993 |
MMM (mitomycin/mitoxantrone/methotrexate): an effective new regimen in the treatment of metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Humans; Melphalan; Menopause; Methotrexate; Middle Aged; Mitomycin; Neoplasm Metastasis; Neoplasm Staging; Vincristine | 1993 |
Regional perfusion with hemofiltration (chemofiltration) for the treatment of patients with regionally advanced cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Renal Cell; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Digestive System Neoplasms; Female; Fluorouracil; Genital Neoplasms, Female; Hemofiltration; Humans; Kidney Neoplasms; Male; Melanoma; Melphalan; Middle Aged; Mitomycin; Prognosis; Survival Rate | 1996 |
Early stem cell transplantation for chronic lymphocytic leukaemia: a chance for cure?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chlorambucil; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Fluorouracil; Follow-Up Studies; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Hydrocortisone; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Melphalan; Methotrexate; Methylprednisolone; Middle Aged; Mitomycins; Prednisone; Prospective Studies; Treatment Outcome; Vincristine | 1998 |
Safety and efficacy of using a single agent or a phase II agent before instituting standard combination chemotherapy in previously untreated metastatic breast cancer patients: report of a randomized study--Cancer and Leukemia Group B 8642.
Topics: Adenine; Adult; Aged; Aminoglycosides; Analysis of Variance; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Imides; Isoquinolines; Melphalan; Middle Aged; Naphthalimides; Neoplasm Staging; Organophosphonates; Prospective Studies; Survival Analysis; Trimetrexate | 1999 |
The impact of induction duration and the number of high-dose cycles on the long-term survival of women with metastatic breast cancer treated with high-dose chemotherapy with stem cell rescue: an analysis of sequential phase I/II trials from the Dana-Farbe
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Estrogens; Female; Fluorouracil; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Life Tables; Melphalan; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Paclitaxel; Peripheral Blood Stem Cell Transplantation; Progesterone; Prognosis; Proportional Hazards Models; Remission Induction; Survival Analysis; Thiotepa; Time Factors; Treatment Outcome | 2002 |
Adjuvant chemotherapy with cyclophosphamide, methotrexate, and 5-fluorouracil, vincristine, and prednisone compared with single-agent L-phenylalanine mustard for patients with operable breast carcinoma and positive axillary lymph nodes: 20-year results of
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Mastectomy, Modified Radical; Mastectomy, Radical; Melphalan; Menopause; Methotrexate; Middle Aged; Prednisone; Survival Rate; Vincristine | 2003 |
Patterns of locoregional failure in patients with operable breast cancer treated by mastectomy and adjuvant chemotherapy with or without tamoxifen and without radiotherapy: results from five National Surgical Adjuvant Breast and Bowel Project randomized c
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Proportional Hazards Models; Statistics, Nonparametric; Survival Analysis; Tamoxifen; Treatment Outcome | 2004 |
Intensity-modulated radiation therapy with simultaneous integrated boost combined with concurrent chemotherapy for the treatment of anal cancer patients: 4-year results of a consecutive case series.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradiotherapy; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Male; Melphalan; Middle Aged; Proportional Hazards Models; Radiotherapy, Intensity-Modulated; Semustine | 2015 |
221 other study(ies) available for fluorouracil and melphalan
| Article | Year |
|---|---|
Antitumor and antiinflammatory agents: N-benzoyl-protected cyanomethyl esters of amino acids.
Topics: Acetonitriles; Amino Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Body Temperature; Carcinoma, Ehrlich Tumor; Carrageenan; Esters; Immunosuppressive Agents; Lethal Dose 50; Leukemia P388; Male; Mice; Mice, Inbred DBA; Rats; Reaction Time; Structure-Activity Relationship | 1979 |
Antineoplastic agents. 2. Structure-activity studies on N-protected vinyl, 1,2-dibromoethyl, and cyanomethyl esters of several amino acids.
Topics: Acetonitriles; Amino Acids; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Lethal Dose 50; Leukemia, Experimental; Mice; Structure-Activity Relationship; Vinyl Compounds | 1977 |
Antitumor agents. 31. Helenalin sym-dimethylethylenediamine reaction products and related derivatives.
Topics: Alkylating Agents; Animals; Carcinoma 256, Walker; Cells, Cultured; Chemical Phenomena; Chemistry; Ethylenediamines; Lactams; Leukemia, Experimental; Male; Mice; Rats; Sesquiterpenes; Sesquiterpenes, Guaiane | 1978 |
Antitumor agents 32. Synthesis and antitumor activity of cyclopentenone derivatives related to helenalin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma 256, Walker; Cells, Cultured; Cyclopentanes; Leukemia, Experimental; Leukemia, Lymphoid; Male; Mice; Mice, Inbred DBA; Rats; Sesquiterpenes; Sesquiterpenes, Guaiane | 1978 |
Antitumor agents. 25. Synthesis and antitumor activity of uracil and thymine alpha-methylene-gamma-lactones and related derivatives.
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Lactones; Leukemia, Experimental; Male; Melanoma; Mice; Neoplasms, Experimental; Rats; Thymine; Uracil | 1977 |
Heterocyclic quinones. 17. A new in vivo active antineoplastic drug: 6,7-bis(1-aziridinyl)-4-[[3-(N,N-dimethylamino)propyl]amino]-5,8- quinazolinedione.
Topics: Animals; Antineoplastic Agents; Aziridines; Breast Neoplasms; Cell Division; Cell Line; Drug Screening Assays, Antitumor; Female; Humans; Leukemia L1210; Leukemia, Experimental; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Molecular Structure; Neoplasms, Experimental; Quinazolines; Sarcoma, Experimental; Structure-Activity Relationship | 1991 |
Synthesis and antiviral and cytotoxic activity of iodohydrin and iodomethoxy derivatives of 5-vinyl-2'-deoxyuridines, 2'-fluoro-2'-deoxyuridine, and uridine.
Topics: Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Biological Transport; Cell Survival; Chemical Phenomena; Chemistry; Deoxyuridine; In Vitro Techniques; Leukemia L1210; Leukemia P388; Mice; Tumor Cells, Cultured; Uridine; Vinyl Compounds | 1990 |
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Antitumor agents: diazomethyl ketone and chloromethyl ketone analogues prepared from N-tosyl amino acids.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Diazomethane; Ketones; Leukemia P388; Male; Mice; Mice, Inbred DBA; Structure-Activity Relationship; Tosyl Compounds | 1980 |
Sequential cytotoxicity: a theory evaluated using novel 2-[4-(3-aryl-2-propenoyloxy)phenylmethylene]cyclohexanones and related compounds.
Topics: Animals; Antineoplastic Agents; Apoptosis; Crystallography, X-Ray; Cyclohexanones; Drug Screening Assays, Antitumor; Humans; Mannich Bases; Mice; Models, Molecular; Neoplasm Proteins; RNA, Neoplasm; Structure-Activity Relationship; Tumor Cells, Cultured | 2000 |
Antitumor-active cobalt-alkyne complexes derived from acetylsalicylic acid: studies on the mode of drug action.
Topics: Alkynes; Antineoplastic Agents; Apoptosis; Aspirin; Cell Line, Tumor; Cell Nucleus; Cobalt; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA; Drug Screening Assays, Antitumor; Enzyme-Linked Immunosorbent Assay; Humans; Membrane Proteins; Organometallic Compounds; Prostaglandin-Endoperoxide Synthases | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Discovery of antiglioma activity of biaryl 1,2,3,4-tetrahydroisoquinoline derivatives and conformationally flexible analogues.
Topics: Animals; Antineoplastic Agents; Astrocytes; Biphenyl Compounds; Cell Line, Tumor; Cells, Cultured; Drug Screening Assays, Antitumor; Glioma; Humans; Isoquinolines; Molecular Conformation; Rats; Structure-Activity Relationship; Tetrahydroisoquinolines | 2006 |
Design, synthesis and cytotoxic properties of novel 1-[4-(2-alkylaminoethoxy)phenylcarbonyl]-3,5-bis(arylidene)-4-piperidones and related compounds.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Humans; Mice; Piperidones; Structure-Activity Relationship | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
E,E,E-1-(4-Arylamino-4-oxo-2-butenoyl)-3,5-bis(arylidene)-4-piperidones: a topographical study of some novel potent cytotoxins.
Topics: Amination; Animals; Cell Line; Cell Survival; Cytotoxins; Humans; Inhibitory Concentration 50; Mice; Models, Molecular; Molecular Structure; Piperidones; Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water | 2010 |
3,5-Bis(benzylidene)-1-[3-(2-hydroxyethylthio)propanoyl]piperidin-4-ones: a novel cluster of potent tumor-selective cytotoxins.
Topics: Animals; Benzylidene Compounds; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Mice; Piperidines; Structure-Activity Relationship; Sulfides | 2011 |
Dimeric 3,5-bis(benzylidene)-4-piperidones: a novel cluster of tumour-selective cytotoxins possessing multidrug-resistant properties.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dimerization; Drug Resistance, Multiple; Humans; Inhibitory Concentration 50; Piperidones | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Novel 3,5-bis(arylidene)-4-oxo-1-piperidinyl dimers: structure-activity relationships and potent antileukemic and antilymphoma cytotoxicity.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dimerization; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; HL-60 Cells; Humans; Leukemia; Lymphoma; Molecular Structure; Piperidines; Structure-Activity Relationship | 2014 |
3,5-Bis(3-alkylaminomethyl-4-hydroxybenzylidene)-4-piperidones: A Novel Class of Potent Tumor-Selective Cytotoxins.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Benzylidene Compounds; Cell Line, Tumor; Cell Proliferation; Cytotoxins; DNA Fragmentation; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Melphalan; Mice; Piperidones; Poly(ADP-ribose) Polymerases; Structure-Activity Relationship | 2016 |
Ovarian function in patients receiving adjuvant chemotherapy for breast cancer.
Topics: Adult; Aged; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Dehydroepiandrosterone; Drug Therapy, Combination; Estradiol; Estrone; Female; Fluorouracil; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Lymphatic Metastasis; Melphalan; Menopause; Methotrexate; Middle Aged; Ovary; Vincristine | 1977 |
Ovarian function and adjuvant chemotherapy for breast cancer.
Topics: Adult; Age Factors; Aged; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Melphalan; Middle Aged; Ovary; Prednisone; Recurrence | 1978 |
[Chemotherapy as an adjuvant treatment in breast cancer (author's transl)].
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Fluorouracil; Humans; Melphalan; Methotrexate; Thiotepa | 1978 |
Regression of established tumors and induction of tumor immunity by intratumor chemotherapy.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Carmustine; Dacarbazine; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Graft Rejection; Guinea Pigs; Injections; Injections, Intraperitoneal; Liver Neoplasms; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Neoplasm Transplantation; Neoplasms, Experimental | 1976 |
Current trends and prospects in surgical adjuvant trials.
Topics: Antineoplastic Agents; Breast Neoplasms; Cisplatin; Colonic Neoplasms; Cyclophosphamide; Dianhydrogalactitol; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Melphalan; Methotrexate; Neoplasms; Osteosarcoma; Rectal Neoplasms | 1978 |
A long lasting proliferative defect in the hematopoietic stem cell compartment following cytotoxic agents.
Topics: Animals; Antineoplastic Agents; Bone Marrow Transplantation; Busulfan; Cell Division; Cyclophosphamide; Fluorouracil; Hematopoietic Stem Cells; Male; Melphalan; Mice; Mice, Inbred C3H; Time Factors; Transplantation, Isogeneic | 1979 |
Acute leukemia after alkylating-agent therapy of ovarian cancer.
Topics: Acute Disease; Alkylating Agents; Altretamine; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Melphalan; Middle Aged; Neoplasm Metastasis; Ovarian Neoplasms; Risk; Thiotepa; Time Factors; Uracil Mustard | 1977 |
[Chemotherapy of the ovarian carcinoma (author's transl)].
Topics: Altretamine; Antineoplastic Agents; Chlorambucil; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hydroxyprogesterones; Mechlorethamine; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Nitrosourea Compounds; Ovarian Neoplasms; Thiotepa; Vinblastine; Vincristine | 1977 |
United States trials of adjuvant therapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Menopause; Methotrexate; Thiotepa | 1977 |
Current concepts in the management of ovarian cancer.
Topics: Adult; Aged; Altretamine; Castration; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; United States | 1978 |
Chemotherapy for breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Vincristine | 1979 |
Hormonal regulation of the menstrual cycle in women with breast cancer: effect of adjuvant chemotherapy.
Topics: Adult; Breast Neoplasms; Estradiol; Female; Fluorouracil; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Melphalan; Menstruation; Middle Aged; Progesterone; Prolactin | 1979 |
[Comparison of the results of single-drug and combination chemotherapy of advanced ovarian cancer after 1 year].
Topics: Antineoplastic Agents; Dactinomycin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Melphalan; Methotrexate; Ovarian Neoplasms; Time Factors; Vincristine | 1979 |
Melphalan and 5-fluorouracil in advanced gastrointestinal carcinoma: a preliminary report.
Topics: Adult; Aged; Bone Marrow; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Humans; Melphalan; Middle Aged; Remission, Spontaneous | 1979 |
Recent trends in breast cancer treatment.
Topics: Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Hormones; Humans; Immunotherapy; Mastectomy; Melphalan; Methotrexate; Neoplasm Metastasis | 1978 |
Phase II study of melphalan in colorectal carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Male; Melphalan; Middle Aged; Neoplasm Metastasis; Prospective Studies; Rectal Neoplasms; Semustine | 1978 |
Detection of mutagenic activity in human urine using mutant strains of Salmonella typhimurium.
Topics: Antineoplastic Agents; Biological Assay; Cyclophosphamide; Ethylnitrosourea; Fluorouracil; Humans; Mechlorethamine; Melphalan; Metronidazole; Mitomycins; Mutagens; Neoplasms; Salmonella typhimurium | 1976 |
Immunological overshoot phenomenon following cancer chemotherapy: significance in prognosis evaluation of solid tumors.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immune Adherence Reaction; Liver Neoplasms; Lung Neoplasms; Lymphocyte Activation; Melphalan; Methotrexate; Neoplasms; Ovarian Neoplasms; Thiotepa; Vincristine | 1975 |
Chemotherapy in advanced ovarian cancer.
Topics: Altretamine; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Ovarian Neoplasms | 1975 |
Comparison of adjuvant chemotherapeutic activity against primary and metastatic spontaneous murine tumors.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Melphalan; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasms, Multiple Primary | 1977 |
Multiple drug chemotherapy regimen for patients with hormonally-unresponsive carcinoma of the prostate: a preliminary report.
Topics: Administration, Oral; Antineoplastic Agents; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Estrogens; Fluorouracil; Follow-Up Studies; Humans; Injections, Intravenous; Male; Melphalan; Methotrexate; Neoplasm Metastasis; Prednisone; Prostatic Neoplasms; Vincristine | 1977 |
Therapy of primary breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Menopause; Methotrexate; Postoperative Care; Prednisone; Vincristine | 1977 |
Treatment of advanced adenocarcinoma of the endometrium with melphalan, 5-fluorouracil, and medroxyprogesterone acetate: a preliminary study.
Topics: Adenocarcinoma; Aged; Drug Therapy, Combination; Female; Fluorouracil; Humans; Medroxyprogesterone; Melphalan; Middle Aged; Uterine Neoplasms | 1977 |
Enhancement and inhibition of mammary tumor formation and growth by cytostatic drugs.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Female; Fluorouracil; Mammary Neoplasms, Experimental; Melphalan; Methotrexate; Mice; Mice, Inbred BALB C; Precancerous Conditions; Prednisone; Vincristine | 1977 |
Serial carcinoembryonic antigen assays in patients with metastatic carcinoma of prostate being treated with chemotherapy.
Topics: Acid Phosphatase; Adenocarcinoma; Carcinoembryonic Antigen; Drug Therapy, Combination; Fluorouracil; Humans; Male; Melphalan; Methotrexate; Neoplasm Metastasis; Prednisone; Prostatic Neoplasms; Vincristine | 1976 |
Clinical chemistry and breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Melphalan; Methotrexate; Neoplasm Recurrence, Local; Risk | 1976 |
The role of chemotherapy in the treatment of breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Methotrexate; Prognosis; Time Factors | 1976 |
Effect of cytostatic drugs on nucleic acid synthesis in mouse thymocytes and chick embryo cells.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Chick Embryo; Cytarabine; Dactinomycin; Deoxyadenosines; Deoxyuridine; DNA; Fluorouracil; Melphalan; Methotrexate; Mice; Mice, Inbred Strains; Thymidine; Thymus Gland; Triaziquone; Tritium; Uridine; Vinblastine | 1975 |
Chemotherapy of breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasm Metastasis; Prednisone; Prognosis; Vincristine | 1975 |
Letter: drugs for common cancers.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Vincristine | 1975 |
Chemotherapy in the treatment strategy of breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prednisone | 1975 |
Sequential therapy for advanced ovarian adenocarcinoma: operation, chemotherapy, second-look laparotomy, and radiation therapy.
Topics: Adenocarcinoma; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Laparotomy; Melphalan; Neoplasm Metastasis; Neoplasm Recurrence, Local; Ovarian Neoplasms | 1975 |
The effect of cytostatic drugs on the synthesis of DNA in adenocarcinomas of the stomach. An in vitro study.
Topics: Adenocarcinoma; Antineoplastic Agents; Cells, Cultured; Depression, Chemical; DNA, Neoplasm; Fluorouracil; Humans; In Vitro Techniques; Melphalan; Methotrexate; Stomach Neoplasms; Thymidine; Tritium; Uridine; Vinblastine | 1975 |
Schedule-dependent synergistic cytotoxicity of arabinofuranosylcytosine with adriamycin or 3,6-bis(5-chloro-2-piperidinyl)-2,5-piperazinedione in cultured cells.
Topics: Cell Division; Cells, Cultured; Cytarabine; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Melphalan; Piperazines; Piperidines | 1975 |
Heterogeneity of human adenocarcinomas of the colon and the stomach as regards sensitivity to cytostatic drugs.
Topics: Adenocarcinoma; Antineoplastic Agents; Colonic Neoplasms; Cytarabine; Fluorouracil; Humans; Melphalan; Methotrexate; Stomach Neoplasms; Vinblastine | 1975 |
Results of the Gynecologic Oncology Group trials on ovarian cancer: preliminary report.
Topics: Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Ovarian Neoplasms | 1975 |
Editorial: Major advance in breast-cancer therapy.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Methotrexate; Neoplasm Metastasis; Prednisone; Time Factors; Vincristine | 1976 |
The effect of Corynebacterium parvum in combination with 5-fluorouracil, L-phenylalanine mustard, or methotrexate on the inhibition of tumor growth.
Topics: Animals; Cell Division; Cyclophosphamide; Drug Synergism; Female; Fluorouracil; Immunotherapy; Mammary Neoplasms, Experimental; Melphalan; Methotrexate; Mice; Mice, Inbred C3H; Propionibacterium acnes | 1976 |
Standardized kinetic microassay to quantify differential chemosensitivity on the basis of proliferative activity.
Topics: Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Division; Cisplatin; Diethylstilbestrol; Drug Screening Assays, Antitumor; Female; Fluorouracil; Gentian Violet; Humans; Kinetics; Melphalan; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Receptors, Progesterone; Tumor Cells, Cultured; Vinblastine | 1992 |
Uterine mullerian adenosarcoma following adenomyoma in a woman on tamoxifen therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Transformation, Neoplastic; Combined Modality Therapy; Doxorubicin; Endometriosis; Female; Fluorouracil; Humans; Melphalan; Menopause; Middle Aged; Tamoxifen; Uterine Neoplasms; Wilms Tumor | 1992 |
Prognostic factors in node-positive operable breast cancer patients receiving adjuvant chemotherapy.
Topics: Breast Neoplasms; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Middle Aged; Prognosis; Retrospective Studies | 1992 |
High-dose melphalan with 6-hydroxydopamine-purged autologous bone marrow transplantation for poor-risk neuroblastoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dianhydrogalactitol; Doxorubicin; Female; Fluorouracil; Humans; Hydroxydopamines; Hydroxyurea; Infant; Male; Melphalan; Neoplasm Staging; Neuroblastoma; Oxidopamine; Prognosis; Radiotherapy Dosage; Remission Induction; Survival Rate; Vincristine; Whole-Body Irradiation | 1991 |
Weight gain with breast cancer adjuvant treatment.
Topics: Adaptation, Psychological; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Melphalan; Methotrexate; Middle Aged; Prednisone; Recurrence; Regression Analysis; Social Support; Vinblastine; Weight Gain | 1991 |
Therapeutic effectiveness against MOPC-315 plasmacytoma of low or high doses of the synthetic thymic hormone THF-gamma 2 in combination with an "immunomodulating" or a "non-immunomodulating" drug.
Topics: Animals; Cell Line; Combined Modality Therapy; Dose-Response Relationship, Drug; Fluorouracil; Immunotherapy; Melphalan; Mice; Mice, Inbred BALB C; Oligopeptides; Plasmacytoma; Thymus Hormones | 1991 |
Relationship between glutathione levels and drug or radiation sensitivities in human gastric cancer cell lines in vitro.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Chlorambucil; Cyclophosphamide; Doxorubicin; Drug Resistance; Fluorouracil; Glutathione; Humans; Melphalan; Radiation Tolerance; Semustine; Stomach Neoplasms; Tumor Cells, Cultured | 1991 |
[Antineoplastic activity of combinations of cytostatics and dextran-ferrite administered to mice with leukemia P-388].
Topics: Animals; Antineoplastic Agents; Cisplatin; Cyclophosphamide; Dactinomycin; Daunorubicin; Doxorubicin; Drug Combinations; Fluorouracil; Iron-Dextran Complex; Leukemia P388; Melphalan; Methotrexate; Mice; Tegafur | 1990 |
[Kinetics of etoposide cytotoxicity against mouse P388 leukemia].
Topics: Animals; Bleomycin; Cell Cycle; Cell Survival; Cisplatin; Colony-Forming Units Assay; Cytarabine; Doxorubicin; Etoposide; Fluorouracil; Leukemia P388; Leukemia, Experimental; Melphalan; Mice; Peplomycin; Podophyllotoxin; Tumor Stem Cell Assay; Vinblastine | 1985 |
[A new in vitro chemosensitivity test. Individualized chemotherapy against ovarian cancer and its clinical effect].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Child; Cisplatin; Colony-Forming Units Assay; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Nimustine; Nitrosourea Compounds; Ovarian Neoplasms; Tumor Stem Cell Assay | 1985 |
[A study of the antineoplastic activity of K18].
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line; Drug Combinations; Drug Synergism; Fluorouracil; gamma-Globulins; Humans; Immunotoxins; Melphalan; Mice; Mice, Nude; Mitomycin; Mitomycins; Neoplasm Transplantation; Stomach Neoplasms; Tissue Distribution | 1986 |
Acute and late toxicity associated with sequential bleomycin-containing chemotherapy regimens and radiation therapy in the treatment of carcinoma of the nasopharynx.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Fluorouracil; Follow-Up Studies; Humans; Melphalan; Methotrexate; Nasopharyngeal Neoplasms; Neoplasm Staging; Prognosis; Radiotherapy Dosage | 1988 |
[5-FU concentration in portal blood after oral administration of 1-hexylcarbamoyl-5-fluorouracil (HCFU)].
Topics: Administration, Oral; Antineoplastic Agents; Digestive System Neoplasms; Drug Combinations; Fluorouracil; gamma-Globulins; Humans; Immunotoxins; Melphalan; Portal System | 1988 |
Effect of various oxygenation conditions and fluosol-DA on cancer chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Bleomycin; Breast Neoplasms; Carbon Dioxide; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Combinations; Fibrosarcoma; Fluorocarbons; Fluorouracil; Humans; Hydroxyethyl Starch Derivatives; Male; Melphalan; Methotrexate; Mice; Mice, Inbred C3H; Mice, Nude; Neoplasm Transplantation; Neoplasms; Organoplatinum Compounds; Oxygen; Tumor Cells, Cultured | 1988 |
[Combination chemotherapy of MCNU, melphalan, procarbazine, and prednisolone (MMPP) in multiple myeloma; disappearance of M-peak on serum electrophoretic pattern].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Doxorubicin; Drug Evaluation; Electrophoresis; Female; Fluorouracil; Humans; Male; Melphalan; Middle Aged; Multiple Myeloma; Myeloma Proteins; Nitrosourea Compounds; Peplomycin; Prednisolone; Procarbazine | 1989 |
Advanced prostatic carcinoma: pulmonary manifestations.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Fluorouracil; Humans; Lung; Lung Neoplasms; Lymphatic Metastasis; Male; Melphalan; Methotrexate; Middle Aged; Pleural Effusion; Prednisone; Prostatic Neoplasms; Radiography; Retrospective Studies; Vincristine | 1985 |
[Various doses cisplatin combined with multi-drug chemotherapy of malignant solid tumors].
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Humans; Lomustine; Lung Neoplasms; Male; Melanoma; Melphalan; Methotrexate; Middle Aged; Neoplasms; Procarbazine; Testicular Neoplasms; Vincristine | 1989 |
A comparison of two and three years of adjuvant tamoxifen.
Topics: Adult; Breast Neoplasms; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Middle Aged; Tamoxifen; Time Factors | 1989 |
Antagonism of chemotherapy-induced cytotoxicity for human breast cancer cells by antiestrogens.
Topics: Breast Neoplasms; Cell Cycle; Cell Survival; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Estrogen Antagonists; Fluorouracil; Humans; Melphalan; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured | 1989 |
The difference between 5-fluorouracil and melphalan in their ability to promote antitumor immune response against MOPC-315 plasmacytoma.
Topics: Adjuvants, Immunologic; Animals; Concanavalin A; Cytotoxicity, Immunologic; Fluorouracil; Lymphocyte Activation; Melphalan; Mice; Mice, Inbred BALB C; Myeloma Proteins; Phytohemagglutinins; Plasmacytoma; Spleen; T-Lymphocytes, Regulatory | 1986 |
The response to further chemotherapy in patients with carcinoma of the breast who progressed while receiving adjuvant therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Tamoxifen; Vincristine | 1985 |
Osteonecrosis of bone associated with combination chemotherapy without corticosteroids.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cyclophosphamide; Doxorubicin; Female; Femur; Fluorouracil; Humans; Melphalan; Osteonecrosis; Radiography | 1986 |
Effects of defined medium, fetal bovine serum, and human serum on growth and chemosensitivities of human breast cancer cells in primary culture: inference for in vitro assays.
Topics: Animals; Antineoplastic Agents; Blood; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cattle; Cell Division; Cells, Cultured; Culture Media; DNA; Doxorubicin; Epithelium; Female; Fetal Blood; Fluorouracil; Humans; Melphalan; Microscopy, Electron | 1987 |
Chemo- and immunotherapy of an adenovirus-induced transplantable sarcoma in hamsters.
Topics: Adenoviridae Infections; Alkylating Agents; Animals; Antimetabolites; Cricetinae; Cyclophosphamide; Female; Fluorouracil; Immunotherapy; Male; Melphalan; Mercaptopurine; Mesocricetus; Methotrexate; Mycobacterium bovis; Neoplasm Transplantation; Sarcoma, Experimental; Semustine | 1987 |
Antineoplastic drug cytotoxicity in a human bladder cancer cell line: implications for intravesical chemotherapy.
Topics: Administration, Intravesical; Antineoplastic Agents; Cell Survival; Cisplatin; Doxorubicin; Fluorouracil; Humans; In Vitro Techniques; Melphalan; Mitomycin; Mitomycins; Tumor Stem Cell Assay; Urinary Bladder Neoplasms; Vincristine | 1987 |
Modulation of induced resistance to adriamycin in two human breast cancer cell lines with tamoxifen or perhexiline maleate.
Topics: Breast Neoplasms; Cell Line; Doxorubicin; Drug Interactions; Drug Resistance; Fluorouracil; Humans; Melphalan; Methotrexate; Perhexiline; Tamoxifen; Tumor Stem Cell Assay; Vinblastine | 1988 |
[Biorhythms and drug therapy].
Topics: Animals; Antineoplastic Agents; Circadian Rhythm; Fluorouracil; Melphalan; Mice; Neoplasms, Experimental; Olivomycins; Time Factors | 1987 |
[Chronobiological approach in the experimental development of regimens for the combined chemotherapy of tumors].
Topics: Aging; Animals; Antineoplastic Combined Chemotherapy Protocols; Chronobiology Phenomena; Circadian Rhythm; Fluorouracil; Melphalan; Methods; Mice; Neoplasms, Experimental; Olivomycins; Time Factors | 1986 |
Clinical pharmacology and cancer chemotherapy: an evolving interface?
Topics: Administration, Oral; Allopurinol; Antineoplastic Agents; Biological Availability; Chemotherapy, Cancer, Regional Perfusion; Drug Evaluation; Fluorouracil; Humans; Infusions, Intravenous; Kinetics; Melphalan; Mercaptopurine; Methotrexate; Pharmaceutical Vehicles | 1986 |
Role of steroid hormone receptors as prognostic factors in primary breast cancer.
Topics: Adult; Breast Neoplasms; Female; Fluorouracil; Humans; Melphalan; Middle Aged; Neoplasm Staging; Prognosis; Prospective Studies; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1986 |
Cell kinetics in selection and stratification of patients for adjuvant therapy of breast carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Carcinoma in Situ; Cell Cycle; DNA, Neoplasm; Epithelium; Evaluation Studies as Topic; Female; Flow Cytometry; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasm Invasiveness; Neoplasm Staging; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Thymidine; Tritium | 1986 |
Prognostic and therapeutic significance of pathological features of breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Female; Fluorouracil; Humans; Lymph Nodes; Mastectomy; Melphalan; Methotrexate; Middle Aged; Prognosis | 1986 |
Use of tamoxifen in breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Tamoxifen | 1985 |
[Cytostatic polychemotherapy in the aged].
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Fluorouracil; Humans; Lymphoma; Male; Melphalan; Methotrexate; Middle Aged; Multiple Myeloma; Prednisolone; Prednisone; Procarbazine; Risk; Vincristine | 1985 |
Combination chemotherapy of breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Prednisone; Vincristine | 1985 |
Single agent vs. combination chemotherapy for ovarian cancer.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Melphalan; Ovarian Neoplasms; Random Allocation; Time Factors | 1985 |
In vitro evaluation of anticancer drugs against ovarian cancer at concentrations achievable by intraperitoneal administration.
Topics: Anthraquinones; Antineoplastic Agents; Cisplatin; Colony-Forming Units Assay; Cytarabine; Doxorubicin; Female; Fluorouracil; Humans; Infusions, Parenteral; Melphalan; Mitomycin; Mitomycins; Mitoxantrone; Ovarian Neoplasms; Peritoneal Cavity; Tumor Stem Cell Assay | 1985 |
Weight gain during adjuvant chemotherapy for breast cancer.
Topics: Adult; Aged; Body Weight; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Prognosis; Risk | 1985 |
Factors affecting growth and drug sensitivity of mouse mammary tumor lines in collagen gel cultures.
Topics: Animals; Cells, Cultured; Collagen; Colony-Forming Units Assay; DNA, Neoplasm; Female; Fluorouracil; Gels; Mammary Neoplasms, Experimental; Melphalan; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Tumor Stem Cell Assay | 1985 |
[Indication and achievements of after-care examinations of urologic tumors. Chemotherapeutic report].
Topics: Aftercare; Antineoplastic Agents; Bleomycin; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Mitomycins; Plicamycin; Postoperative Complications; Procarbazine; Urogenital Neoplasms; Vinblastine | 1973 |
[The effect of cytostatic drugs on blood platelets and lymphocytes in patients with neoplasms].
Topics: Adenine Nucleotides; Adenosine Diphosphate; Amidines; Antibiotics, Antineoplastic; Bleomycin; Blood Platelets; Breast Neoplasms; Bronchial Neoplasms; Cyclophosphamide; Doxorubicin; Firefly Luciferin; Fluorouracil; Glyoxal; Hodgkin Disease; Humans; Hydrazones; Leukemia; Luciferases; Lymphocytes; Melphalan; Methotrexate; Neoplasms; Nephelometry and Turbidimetry; Plasmacytoma; Platelet Aggregation; Vinca Alkaloids | 1974 |
Uric acid excretion following pelvic perfusion for malignancy.
Topics: Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Humans; Melphalan; Methotrexate; Palliative Care; Pelvic Neoplasms; Tourniquets; Uric Acid | 1967 |
[Study of the action of antitumor compounds on primary explants from human tumors].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adenocarcinoma, Scirrhous; Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Squamous Cell; Culture Techniques; Flavonoids; Fluorouracil; HeLa Cells; Humans; Lung Neoplasms; Melphalan; Mercaptopurine; Methods; Mitomycins; Neoplasms; Rectal Neoplasms; Stomach Neoplasms | 1967 |
[Detection of a moderate staphylococcal phage by means of antineoplastic agents].
Topics: Aminopterin; Antibiotics, Antineoplastic; Anticholesteremic Agents; Antimetabolites; Antineoplastic Agents; Chlorambucil; Colchicine; Cyclophosphamide; Dactinomycin; Drug Resistance, Microbial; Flavonoids; Fluorouracil; Lysogeny; Mechlorethamine; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Olivomycins; Staphylococcus; Staphylococcus Phages; Thiotepa; Ultraviolet Rays; Uracil; Vinblastine; Vincristine | 1970 |
[Chromosomal studies in correlation with other biologic constants in neoplasms treated by chemotherapy].
Topics: Adult; Antibody Formation; Bone Marrow; Cell Division; Chromosome Aberrations; Female; Fluorouracil; Humans; Immunity, Cellular; Male; Melphalan; Methotrexate; Middle Aged; Mitosis; Neoplasms; Thiotepa | 1974 |
The growth of human tumours in immunosuppressed mice and their response to chemotherapy.
Topics: Animals; Chlorambucil; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Immunosuppression Therapy; Male; Melphalan; Methotrexate; Mice; Mice, Inbred CBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Ovarian Neoplasms; Thiotepa; Thymectomy; Transplantation, Heterologous; Triaziquone; Urinary Bladder Neoplasms; Vinblastine; Vincristine | 1974 |
Breast cancer management.
Topics: Alabama; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy; Melphalan; Methotrexate; Middle Aged; Surveys and Questionnaires; Thiotepa | 1974 |
[Intra-arterial chemotherapy in stomach cancer].
Topics: Animals; Benzene Derivatives; Chemotherapy, Cancer, Regional Perfusion; Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intra-Arterial; Melphalan; Stomach Neoplasms; Thiotepa | 1974 |
[Characteristics of growth and sensitivity to cytostatics of Walker 256 carcinosarcoma in randombred and Wistar rats].
Topics: Animals; Antineoplastic Agents; Aziridines; Carcinoma 256, Walker; Cyclophosphamide; Fluorouracil; Melphalan; Methotrexate; Nitrofurans; Nitrogen Mustard Compounds; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Species Specificity; Thiotepa | 1974 |
An evaluation of 51 patients with hepatic artery infusion.
Topics: Antineoplastic Agents; Catheterization; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Hepatic Artery; Humans; Injections, Intra-Arterial; Liver Neoplasms; Melphalan; Methotrexate; Neoplasm Metastasis | 1966 |
Responses of freshly cultured tumour cells to certain selected chemotherapeutic agents.
Topics: Adenocarcinoma; Antineoplastic Agents; Chlorambucil; Colchicine; Culture Techniques; Cyclophosphamide; Dactinomycin; Female; Floxuridine; Fluorouracil; Hodgkin Disease; Humans; Melphalan; Mercaptopurine; Methotrexate; Nandrolone; Neoplasms; Nitrogen Mustard Compounds; Norethindrone; Prednisolone; Progesterone; Testosterone; Thiotepa; Uterine Neoplasms; Vinblastine | 1968 |
Perfusion and infusion chemotherapy for cancer of the head and neck.
Topics: Antineoplastic Agents; Bromodeoxyuridine; Carotid Arteries; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Dactinomycin; DNA; Floxuridine; Fluorouracil; Head; Humans; Infusions, Parenteral; Melphalan; Methods; Neck; Nitrogen Mustard Compounds | 1964 |
Chemotherapy in the treatment of cancer of the ovary.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Cyclophosphamide; Cystadenocarcinoma; Dactinomycin; Female; Fluorouracil; Humans; Mechlorethamine; Melphalan; Ovarian Neoplasms; Thiotepa; Vinblastine | 1970 |
Integrated therapy in the treatment of ovarian cancer with surgery, radiation and chemotherapy.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Ascites; Chlorambucil; Cobalt Isotopes; Cyclophosphamide; Cystadenocarcinoma; Dactinomycin; Endometriosis; Female; Fluorouracil; Humans; Melphalan; Ovarian Neoplasms; Radiotherapy, High-Energy; Thiotepa; Vinblastine; Vincristine | 1972 |
Chemotherapy of ovarian cancer. New approaches to treatment.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Antineoplastic Agents; Cyclophosphamide; Cystadenocarcinoma; Dactinomycin; Female; Fluorouracil; Humans; Melphalan; Ovarian Neoplasms | 1972 |
Metastatic ovarian cancer.
Topics: Adenocarcinoma, Mucinous; Cyclophosphamide; Cystadenocarcinoma; Dactinomycin; Drug Combinations; Female; Fluorouracil; Humans; Melphalan; Neoplasm Metastasis; Ovarian Neoplasms | 1973 |
Comparative chemotherapy of AKR lymphoma and human hematological neoplasia.
Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Models, Animal; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Hodgkin Disease; Humans; Leukemia; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Mechlorethamine; Melphalan; Mice; Mice, Inbred AKR; Multiple Myeloma; Nitrosourea Compounds; Prednisone; Remission, Spontaneous; Vinblastine; Vincristine | 1974 |
[Antibodies to sarcolysine and 5-fluorouracil].
Topics: Animals; Antibody Formation; Basophils; Cross Reactions; Dysgerminoma; Erythrocytes; Esophageal Neoplasms; Fluorouracil; Hemagglutination Tests; Humans; Immunization; Immunologic Techniques; Injections, Intradermal; Injections, Intravenous; Male; Melphalan; Rabbits; Rats; Stomach Neoplasms; Time Factors | 1974 |
[Use of transplantability indices of tumor cells for evaluation of the cytotoxic effect of antineoplastic agents in vitro].
Topics: Animals; Cell Line; Cells, Cultured; Culture Media; Fluorouracil; Leukemia, Experimental; Male; Melphalan; Mice; Neoplasm Transplantation; Sarcoma 180; Sarcoma, Experimental; Thiotepa | 1972 |
Incubation of surviving sections of ovarian tumours as a method of testing their sensitivity to cytostatics.
Topics: Culture Techniques; DNA, Neoplasm; Female; Fluorouracil; Humans; Melphalan; Nitrogen Mustard Compounds; Ovarian Neoplasms; Parathion; Thiotepa; Thymidine; Tritium | 1972 |
In vivo determination of the fractional kill of human tumor cells by chemotherapeutic agents.
Topics: Antineoplastic Agents; Cell Survival; Cyclophosphamide; Fluorouracil; Humans; Melphalan; Multiple Myeloma; Myeloma Proteins; Neoplasms; Time Factors | 1972 |
Chemotherapy of mouse myeloma: quantitative cell cultures predictive of response in vivo.
Topics: Animals; Antineoplastic Agents; Bone Marrow Cells; Cells, Cultured; Cyclophosphamide; Female; Fluorouracil; Mechlorethamine; Melphalan; Mice; Multiple Myeloma; Nitrosourea Compounds; Radiation Chimera; Rodent Diseases; Spleen | 1973 |
Sensitivity of human and murine hemopoietic precursor cells to chemotherapeutic agents assessed in cell culture.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Division; Cell Survival; Cells, Cultured; Drug Tolerance; Fluorouracil; Hematopoietic Stem Cells; Humans; Melphalan; Mice; Nitrogen Mustard Compounds; Nitrosourea Compounds; Radiation Effects | 1973 |
The etiocholanolone test for prediction of the leukopenic effect of cytoxic drugs.
Topics: Adult; Antineoplastic Agents; Cell Survival; Cyclophosphamide; Depression, Chemical; Etiocholanolone; Female; Fluorouracil; Humans; Injections, Intramuscular; Leukocyte Count; Leukocytes; Leukopenia; Male; Melphalan; Neoplasms; Stimulation, Chemical | 1973 |
Biological characterization of human tumours by means of organ culture and individualized cytostatic cancer treatment.
Topics: Antineoplastic Agents; Biological Assay; Biopsy; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Male; Melphalan; Methotrexate; Neoplasms; Organ Culture Techniques; Triaziquone; Vinblastine; Vincristine | 1973 |
[Chemotherapy of cancer. Hints for continuing medical education].
Topics: Antineoplastic Agents; Busulfan; Chlorambucil; Cyclophosphamide; Cytarabine; Daunorubicin; Education, Medical, Continuing; Fluorouracil; Humans; Melphalan; Mercaptopurine; Methotrexate; Neoplasms; Procarbazine; Triaziquone; Vinblastine; Vincristine | 1974 |
[A study of the effects of some antineoplastic preparations on human tumor cells (HeLa line) in tissue culture by the time lapse microphotography method].
Topics: Alkylating Agents; Antineoplastic Agents; Fluorouracil; HeLa Cells; Humans; In Vitro Techniques; Melphalan; Methods; Microscopy, Phase-Contrast; Mitosis; Photomicrography; Serotonin; Time Factors | 1967 |
Regional chemotherapy of cancer of the head and neck.
Topics: Antineoplastic Agents; Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Leucovorin; Melanoma; Melphalan; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Paranasal Sinus Neoplasms; Sarcoma; Thiotepa; Vinblastine | 1966 |
Systemic chemotherapy for carcinoma of the cervix.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Humans; Hydroxyurea; Mechlorethamine; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Progestins; Thiotepa; Urea; Uterine Cervical Neoplasms | 1967 |
[Antineoplastic polychemotherapy in thoracic pathology].
Topics: Adrenalectomy; Aged; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Cortisone; Cyclophosphamide; Drug Synergism; Ethinyl Estradiol; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Hydrazines; Hypophysectomy; Kidney Neoplasms; Lung Neoplasms; Male; Melanoma; Melphalan; Mesothelioma; Methotrexate; Middle Aged; Nandrolone; Neoplasm Metastasis; Ovarian Neoplasms; Podophyllin; Sarcoma; Thiotepa; Vinblastine | 1968 |
Relative effects of varying concentrations of cytotoxic drugs in vitro on tumour and reticulo-endothelial tissue.
Topics: Animals; Antineoplastic Agents; DNA; DNA, Neoplasm; Fluorouracil; Glucose; In Vitro Techniques; Mammary Neoplasms, Experimental; Mechlorethamine; Melphalan; Methotrexate; Mice; Mononuclear Phagocyte System; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; RNA; RNA, Neoplasm; Spleen; Thiotepa; Tritium; Vinblastine | 1968 |
Cytotoxic agents in the treatment of malignant disease.
Topics: Antimetabolites; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Female; Fluorouracil; Hodgkin Disease; Humans; Hydrazines; Intestinal Neoplasms; Melphalan; Methotrexate; Multiple Myeloma; Ovarian Neoplasms; Pregnancy; Thiotepa; Vinblastine | 1968 |
[The chemotherapy of cancer].
Topics: Adult; Alkylating Agents; Antimetabolites; Antineoplastic Agents; Dactinomycin; Female; Fluorouracil; Hodgkin Disease; Humans; Lung Neoplasms; Male; Melphalan; Methotrexate; Middle Aged; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum; Radiography; Sarcoma, Ewing; Thiotepa; Vincristine | 1967 |
[On selection of antineoplastic agents for local use].
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Female; Fluorouracil; In Vitro Techniques; Lymphoma, Non-Hodgkin; Melphalan; Mice; Neoplasms, Experimental; Ovarian Neoplasms; Rats; Thiotepa | 1969 |
[On intra-arterial chemotherapy of stomach cancer].
Topics: Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Fluorouracil; Humans; Injections, Intra-Arterial; Melphalan; Methods; Stomach Neoplasms; Thiotepa | 1969 |
[Regional chemotherapy in far advanced forms of cancer of the uterine cervix].
Topics: Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Thiotepa; Uterine Cervical Neoplasms | 1969 |
[The morphologic composition of peripheral blood following intra-arterial infusion of 5-fluorouracil and alkylating preparations in stomach cancer patients].
Topics: Anemia; Fluorouracil; Humans; Leukopenia; Melphalan; Nitrogen Mustard Compounds; Stomach Neoplasms; Thiotepa; Thrombocytopenia | 1970 |
[Effect of antineoplastic agents on the accumulation of collargol in cells of the reticuloendothelial system].
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cytoplasm; Depression, Chemical; Fluorouracil; Liver; Lymph Nodes; Male; Melphalan; Mononuclear Phagocyte System; Nitrogen Mustard Compounds; Rats; Silver; Spleen; Thiotepa; Uracil | 1970 |
[Time factor in evaluating antineoplastic agents].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Dactinomycin; Fluorouracil; Melphalan; Mercaptopurine; Methylthiouracil; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Nitrogen Mustard Compounds; Rats; Sarcoma, Experimental; Time Factors | 1972 |
[Use of the passive hemagglutination test for detecting antibodies to sarcolysin and 5-fluorouracil].
Topics: Animals; Antibodies; Fluorouracil; Haptens; Hemagglutination Tests; Melphalan; Rabbits | 1972 |
[Present status of chemotherapy in gastric cancer in the USSR].
Topics: Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Humans; Injections, Intra-Arterial; Melphalan; Stomach Neoplasms; USSR | 1971 |
A primary melanocarcinoma of the cervix.
Topics: Adult; Cervix Uteri; Female; Fluorouracil; Humans; Imidazoles; Melanoma; Melphalan; Neoplasm Metastasis; Prognosis; Uterine Cervical Neoplasms | 1971 |
Drugs and their abuse no. V--misuse of cytotoxic drugs.
Topics: Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Humans; Leukemia; Mechlorethamine; Melphalan; Methotrexate; Substance-Related Disorders; Vinblastine; Vincristine | 1971 |
[Correlation between lymphocytes and polyblast-macrophages and their cytologic characteristic during the use of antineoplastic agents].
Topics: Animals; Blood Cell Count; Cell Differentiation; Culture Techniques; Cyclophosphamide; Depression, Chemical; Fluorouracil; Immunosuppressive Agents; Lymphocytes; Lymphopenia; Macrophages; Male; Melphalan; Mice; Peritoneal Cavity; Transplantation Immunology | 1971 |
Differential effects of anti-tumour drugs on human tumour and spleen DNA synthesis in vitro.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Culture Techniques; Disease Models, Animal; DNA; Fluorouracil; Melphalan; Methotrexate; Mice; Spleen | 1971 |
Biologic effects of recent antimitotic compounds. A comparative evaluation.
Topics: Animals; Antineoplastic Agents; Chick Embryo; Colchicine; Cyclophosphamide; DNA; Fluorouracil; Humans; Hydrazines; In Vitro Techniques; Leukocytes; Mechlorethamine; Melphalan; Mitosis; Prednisolone; RNA; Triaziquone; Vinblastine; Vincristine | 1968 |
Experimental inhibition of the virus-induced Rauscher leukemia of the mouse.
Topics: Animals; Blood Cell Count; Female; Fluorouracil; Leukemia, Experimental; Male; Melphalan; Mercaptopurine; Mice; Rauscher Virus; Triaziquone | 1968 |
[Tolerance of the stomach wall to antineoplastic preparations].
Topics: Animals; Chemotherapy, Cancer, Regional Perfusion; Dogs; Fluorouracil; Melphalan; Stomach Diseases; Stomach Neoplasms | 1969 |
Dose-response curves for agents that impair cell reproductive integrity. A fundamental difference between dose-response curves of antimetabolites and those for radiation and alkylating agents.
Topics: Alkylating Agents; Animals; Antibody Formation; Antimetabolites; Cell Division; Cyclophosphamide; Fluorouracil; Immunization; Male; Mathematics; Melphalan; Methotrexate; Mice; Models, Biological; Nitrogen Mustard Compounds; Radiation Effects; Spleen; Thioguanine | 1969 |
Transplantable mouse plasma cell tumors in experimental chemotherapy.
Topics: Aniline Compounds; Animals; Antineoplastic Agents; Blood Protein Electrophoresis; Blood Proteins; Chlorambucil; Cyclophosphamide; Erythrocyte Count; Female; Fluorouracil; Hemoglobinometry; Humans; Leukocyte Count; Melphalan; Mercaptopurine; Methods; Methotrexate; Mice; Models, Biological; Mustard Compounds; Neoplasm Transplantation; Neoplasms, Experimental; Peritoneum; Plasma Cells; Plasmacytoma; Time Factors; Transplantation, Homologous; Triethylenemelamine | 1969 |
[Antiblastic effect of various chemotherapeutic preparations on the cells of the Ehrlich ascites tumor].
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Busulfan; Carcinoma, Ehrlich Tumor; Fluorouracil; Mechlorethamine; Melphalan; Mercaptopurine; Mice; Nitrogen Mustard Compounds; Uracil | 1966 |
Disseminated melanoma. Biologic behavior and treatment.
Topics: Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Dactinomycin; Fluorouracil; Humans; Hydrazines; Hydroxyurea; Lymph Node Excision; Lymphatic Metastasis; Melanoma; Melphalan; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Perfusion; Vincristine | 1967 |
Combination chemotherapy for advanced endometrial adenocarcinoma.
Topics: Adenocarcinoma; Aged; Drug Therapy, Combination; Female; Fluorouracil; Humans; Medroxyprogesterone; Melphalan; Middle Aged; Uterine Neoplasms | 1980 |
Intra-arterial infusion of anticancer drugs: theoretic aspects of drug delivery and review of responses.
Topics: Antineoplastic Agents; Bleomycin; Blood Flow Velocity; Doxorubicin; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Parenteral; Injections, Intra-Arterial; Injections, Intravenous; Melphalan; Methotrexate; Models, Biological | 1980 |
A novel dye exclusion method for testing in vitro chemosensitivity of human tumors.
Topics: Antineoplastic Agents; Cell Line; Cell Survival; Doxorubicin; Drug Evaluation, Preclinical; Eosine Yellowish-(YS); Etoposide; Fluorouracil; Hematoxylin; Humans; Leukemia, Myeloid, Acute; Mechlorethamine; Melphalan; Neoplasms; Staining and Labeling | 1983 |
Comparison of drug sensitivity among tumor cells within a tumor, between primary tumor and metastases, and between different metastases in the human tumor colony-forming assay.
Topics: Antineoplastic Agents; Bleomycin; Cell Division; Cell Survival; Cells, Cultured; Cisplatin; Doxorubicin; Fluorouracil; Humans; Kinetics; Male; Melphalan; Mitomycin; Mitomycins; Neoplasm Metastasis; Neoplasms | 1984 |
Repetitive debulking surgery as adjuvant to chemotherapy in advanced epithelial ovarian cancer.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Ovarian Neoplasms; Prospective Studies; Reoperation | 1984 |
The chemotherapy of granulosa cell tumors of the ovary: experience of the Wisconsin Clinical Cancer Center.
Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Granulosa Cell Tumor; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Prednisone; Retrospective Studies; Vincristine | 1984 |
Cross-resistance to cytotoxic drugs in human glioma cell lines in culture.
Topics: Antineoplastic Agents; Cell Line; Cell Survival; Dactinomycin; Doxorubicin; Drug Resistance; Fluorouracil; Glioma; Humans; Melphalan; Podophyllotoxin; Vincristine | 1984 |
Comparison of melphalan with cyclophosphamide, methotrexate, and 5-fluorouracil in patients with ovarian cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Ovarian Neoplasms; Probability; Random Allocation; Time Factors | 1984 |
[Breast cancer--topics from basic research].
Topics: Animals; Breast Neoplasms; Female; Fluorouracil; Humans; Melphalan; Mice; Neoplasms, Hormone-Dependent; Rats; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1984 |
[Breast neoplasms. Progress by means of adjuvant chemotherapy?].
Topics: Age Factors; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Lymphatic Metastasis; Melphalan; Menopause; Methotrexate; Prognosis | 1980 |
Pathologic findings from the National Surgical Adjuvant Breast Project. VIII. Relationship of chemotherapeutic responsiveness to tumor differentiation.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Methotrexate; Middle Aged; Prognosis | 1983 |
[Advanced epithelial cancers of the ovary: results of 4 chemotherapy protocols (110 cases)].
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma; Cisplatin; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Laparotomy; Melphalan; Methotrexate; Middle Aged; Neoplasm Staging; Ovarian Neoplasms | 1982 |
[Hematopoietic resistance to the damaging action of cytostatics in the occurrence of tumor drug resistance].
Topics: Animals; Daunorubicin; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Flavonoids; Fluorouracil; Hematopoiesis; Lymphoma, Non-Hodgkin; Male; Melphalan; Neoplasm Transplantation; Neoplasms, Experimental; Rats | 1981 |
Initial chemoimmunotherapy in inflammatory carcinoma of the breast.
Topics: Aged; Antineoplastic Agents; BCG Vaccine; Breast Neoplasms; Carcinoma; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Thermography; Time Factors; Vincristine | 1982 |
Combination chemotherapy for advanced endometrial cancer. An evaluation of three regimens.
Topics: Antineoplastic Agents; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Megestrol; Melphalan; Uterine Neoplasms | 1982 |
The medical management of breast cancer.
Topics: Adjuvants, Pharmaceutic; Adult; Aminoglutethimide; Antineoplastic Agents; Breast Neoplasms; Castration; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hypophysectomy; Melphalan; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Receptors, Estrogen; Tamoxifen | 1982 |
[Severe intoxication after combined chemotherapy of a sigma-adenocarcinoma with peptichemio and 5-fluorouracil (author's transl)].
Topics: Adenocarcinoma; Alopecia; Candidiasis, Oral; Diarrhea; Female; Fluorouracil; Hepatomegaly; Humans; Melphalan; Middle Aged; Peptichemio; Sigmoid Neoplasms | 1982 |
Chemotherapy of hormone-resistant stage D prostatic cancer.
Topics: Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Estramustine; Fluorouracil; Humans; Hydroxyurea; Lomustine; Male; Melphalan; Methotrexate; Prednimustine; Prostatic Neoplasms | 1980 |
[Results of, and indications for adjuvant chemotherapy in breast cancer].
Topics: Adult; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Melphalan; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Risk; Vincristine | 1981 |
[Use of "split" courses of combination chemotherapy in breast cancer].
Topics: Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasm Metastasis; Prednisolone; Time Factors; Vincristine | 1981 |
Severe intoxication after combined chemotherapy of a sigma-adenocarcinoma with peptichemio and 5-fluorouracil.
Topics: Adenocarcinoma; Female; Fluorouracil; Gastroenteritis; Humans; Leukopenia; Melphalan; Middle Aged; Peptichemio; Sigmoid Neoplasms | 1981 |
Pharmacokinetic approach to in vitro testing of ovarian cancer cell sensitivity.
Topics: Antineoplastic Agents; Cell Survival; Cytarabine; Dactinomycin; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance; Female; Fluorouracil; Half-Life; Humans; In Vitro Techniques; Melphalan; Methotrexate; Ovarian Neoplasms | 1980 |
Melphalan, 5-fluorouracil, and medroxyprogesterone acetate in metastatic or recurrent endometrial carcinoma. Preliminary report.
Topics: Adenocarcinoma; Antineoplastic Agents; Drug Therapy, Combination; Female; Fluorouracil; Humans; Medroxyprogesterone; Melphalan; Neoplasm Metastasis; Neoplasm Recurrence, Local; Uterine Neoplasms | 1980 |
Expression of adhesion molecules on CD34+ cells: CD34+ L-selectin+ cells predict a rapid platelet recovery after peripheral blood stem cell transplantation.
Topics: Adult; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Bone Marrow; Bone Marrow Cells; Carboplatin; Carmustine; Cell Adhesion Molecules; Cell Movement; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Epirubicin; Etoposide; Female; Fluorouracil; Gene Expression; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Ifosfamide; L-Selectin; Leukocyte Count; Male; Melphalan; Middle Aged; Neoplasms; Neutrophils; Platelet Count; Podophyllotoxin; Receptors, Very Late Antigen; Thiotepa | 1995 |
Ethmoid sinus leiomyosarcoma after cyclophosphamide treatment.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinogens; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Ethmoid Sinus; Female; Fluorouracil; Follow-Up Studies; Humans; Leiomyosarcoma; Mastectomy, Modified Radical; Melphalan; Methotrexate; Neoplasms, Second Primary; Paranasal Sinus Neoplasms | 1995 |
[Leukemia in patients with breast carcinoma after adjuvant chemotherapy and/or postoperative radiotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Leukemia; Leukemia, Radiation-Induced; Manitoba; Melphalan; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasms, Second Primary; Postoperative Care; Radiotherapy, Adjuvant; Time Factors | 1995 |
Multiple myeloma. New approaches to therapy.
Topics: Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Genetic Markers; Genetic Therapy; Granulocyte Colony-Stimulating Factor; Humans; Interferon-alpha; Interleukin-6; Melphalan; Middle Aged; Multiple Myeloma; Research; Transplantation, Autologous; Whole-Body Irradiation | 1993 |
Involvement of potassium ions in the action of various antineoplastic drugs on the growth of Saccharomyces cerevisiae.
Topics: Amsacrine; Antineoplastic Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Drug Resistance, Microbial; Fluorouracil; Melphalan; Methotrexate; Potassium Chloride; Saccharomyces cerevisiae | 1993 |
Salivary excretion of anticancer drugs.
Topics: Antineoplastic Agents; Doxorubicin; Drug Monitoring; Etoposide; Fluorouracil; Humans; Injections, Intravenous; Melphalan; Models, Biological; Parotid Gland; Saliva | 1993 |
Cytogenetic findings in 111 ovarian cancer patients: therapy-related chromosome aberrations and heterochromatic variants.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Chromosome Aberrations; Chromosome Deletion; Chromosome Inversion; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 9; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Heterochromatin; Humans; Karyotyping; Melphalan; Methotrexate; Middle Aged; Mitomycins; Neoplasms, Second Primary; Ovarian Neoplasms; Radiotherapy; Translocation, Genetic; Vincristine | 1993 |
Thymic humoral factor-gamma 2 (THF-gamma 2) immunotherapy reduces the metastatic load and restores immunocompetence in 3LL tumor-bearing mice receiving anticancer chemotherapy.
Topics: Animals; Drug Synergism; Drug-Related Side Effects and Adverse Reactions; Erythrocytes; Female; Fluorouracil; Granulocyte-Macrophage Colony-Stimulating Factor; Immune Sera; Immunity; Immunotherapy; Lipopolysaccharides; Lung Neoplasms; Male; Melphalan; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasms, Experimental; Oligopeptides; Thymus Hormones | 1996 |
Improved priming for mobilization of and optimal timing for harvest of peripheral blood stem cells.
Topics: Adolescent; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Blood Transfusion, Autologous; Bone Marrow; Carmustine; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Drug Synergism; Epirubicin; Etoposide; Female; Filgrastim; Fluorouracil; Granulocyte Colony-Stimulating Factor; Hematologic Neoplasms; Hematopoietic Stem Cells; Humans; Injections, Subcutaneous; Leukapheresis; Leukocyte Count; Male; Melphalan; Middle Aged; Neoplasms; Recombinant Proteins | 1996 |
Inhibition of murine Lewis lung carcinoma metastases by combined chemotherapy and intranasal THF-gamma 2 immunotherapy.
Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Carcinoma, Lewis Lung; Combined Modality Therapy; Female; Fluorouracil; Immunotherapy, Active; Lung; Lung Neoplasms; Male; Melphalan; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oligopeptides; Organ Size; Spleen; Survival Analysis; T-Lymphocyte Subsets; Thymus Hormones | 1996 |
Treatment of abdominal malignancies using total abdominal stop-flow infusion and hypoxic perfusion.
Topics: Abdominal Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Doxorubicin; Female; Fluorouracil; Humans; Hypoxia; Melphalan; Mitomycin | 1997 |
Resistance to cytotoxic drugs in DNA mismatch repair-deficient cells.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Antineoplastic Agents; Carboplatin; Carrier Proteins; Cisplatin; Colorectal Neoplasms; Cyclophosphamide; DNA Adducts; DNA Damage; DNA Repair; DNA-Binding Proteins; DNA, Neoplasm; Doxorubicin; Drug Resistance, Neoplasm; Endometrial Neoplasms; Etoposide; Female; Fluorouracil; Humans; Melphalan; Methylnitronitrosoguanidine; Mutagenesis; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neoplasm Proteins; Nuclear Proteins; Paclitaxel; Proto-Oncogene Proteins; Thioguanine; Tumor Cells, Cultured | 1997 |
Chemotherapy augments TRAIL-induced apoptosis in breast cell lines.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Caspase 3; Caspases; Doxorubicin; Enzyme Activation; Fluorouracil; Glutathione Transferase; Humans; Melphalan; Membrane Glycoproteins; Paclitaxel; Recombinant Fusion Proteins; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
[Intratumoral chemotherapy in an experimental animal model: another therapeutic possibility in cancerology].
Topics: Amiodarone; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Cisplatin; Colonic Neoplasms; Coloring Agents; Data Interpretation, Statistical; Enzyme Inhibitors; Epirubicin; Female; Fluorouracil; Infusions, Intra-Arterial; Infusions, Intravenous; Injections, Intralesional; Male; Melphalan; Mitomycins; Neoplasm Transplantation; Rats; Time Factors; Tumor Cells, Cultured | 1999 |
Theoretical considerations and in vitro concentration response studies with two human colorectal carcinoma cell lines. The rational experimental base for clinical studies in regional chemotherapy.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carcinoma; Cisplatin; Colorectal Neoplasms; Doxorubicin; Epirubicin; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Melphalan; Mitomycin; Mitoxantrone; Tumor Cells, Cultured | 2000 |
Continuous hyperthermic peritoneal perfusion (CHPP) for malignant ascites and irresectable intra-abdominal cancer.
Topics: Abdominal Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Ascites; Cell Division; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Hyperthermia, Induced; Infusions, Parenteral; Male; Melphalan; Middle Aged; Mitomycin; Perfusion; Survival Rate | 2000 |
Glutathione depletion causes cell growth inhibition and enhanced apoptosis in pancreatic cancer cells.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Apoptosis; Cell Division; Drug Resistance, Neoplasm; Female; Fluorouracil; Glutathione; Humans; Male; Melphalan; Middle Aged; Pancreatic Neoplasms | 2000 |
The phenotypic profile of CD34-positive peripheral blood stem cells in different mobilization regimens.
Topics: Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Administration Schedule; Filgrastim; Flow Cytometry; Fluorouracil; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Immunophenotyping; Intercellular Adhesion Molecule-1; L-Selectin; Leukapheresis; Megakaryocytes; Melphalan; Multiple Myeloma; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Stem Cells; Vincristine | 2000 |
Synergy of the protein farnesyltransferase inhibitor SCH66336 and cisplatin in human cancer cell lines.
Topics: Alkyl and Aryl Transferases; Antineoplastic Agents; Apoptosis; Cell Cycle; Cisplatin; DNA Adducts; Drug Combinations; Drug Synergism; Fluorouracil; Humans; Melphalan; Piperidines; Platinum; Pyridines; Tumor Cells, Cultured | 2001 |
Schedule-dependent potentiation of chemotherapeutic drugs by the bioreductive compounds NLCQ-1 and tirapazamine against EMT6 tumors in mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Synergism; Etoposide; Female; Fluorouracil; Imidazoles; Mammary Neoplasms, Experimental; Melphalan; Mice; Mice, Inbred BALB C; Paclitaxel; Quinolines; Tirapazamine; Triazines; Tumor Cells, Cultured | 2001 |
Intra-arterial infusion of 5-fluorouracil plus granulocyte-macrophage colony-stimulating factor (GM-CSF) and chemoembolization with melphalan in the treatment of disseminated colorectal liver metastases.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoembolization, Therapeutic; Colorectal Neoplasms; Combined Modality Therapy; Dendritic Cells; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Infusions, Intravenous; Liver Neoplasms; Male; Melphalan; Middle Aged; Prospective Studies; Statistics, Nonparametric; Survival Rate | 2001 |
Cytotoxic analogues of 2,6-bis(arylidene)cyclohexanones.
Topics: Animals; Antineoplastic Agents; Benzene Derivatives; Cell Line; Cyclohexanones; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Leukemia L1210; Leukemia P388; Melphalan; Mice; Structure-Activity Relationship; T-Lymphocytes; Tumor Cells, Cultured | 2003 |
Effect of anticancer drugs on experimental wound healing.
Topics: Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Humans; Mechlorethamine; Melphalan; Thiotepa; Wound Healing | 1962 |
STUDIES WITH THE MURINE LEUKEMOGENIC RAUSCHER VIRUS. II. CHEMOTHERAPY OF VIRUS-INDUCED LYMPHOID LEUKEMIA.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cyclophosphamide; Fluorouracil; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Melphalan; Mercaptopurine; Mice; Oncogenic Viruses; Pathology; Pharmacology; Rauscher Virus; Research; Splenomegaly; Thiosemicarbazones; Vincristine | 1963 |
[INTRAARTERIAL INFUSIONS AND REGIONAL PERFUSION OF ANTIMITOTICS].
Topics: Antimitotic Agents; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Humans; Infusions, Intra-Arterial; Injections; Injections, Intra-Arterial; Melphalan; Methotrexate; Thiotepa | 1964 |
CURRENT STATUS OF CHEMOTHERAPY OF CANCER.
Topics: Alkylating Agents; Anti-Bacterial Agents; Antineoplastic Agents; Black People; Chemotherapy, Cancer, Regional Perfusion; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Dermatologic Agents; DNA; DNA, Neoplasm; Fluorouracil; Geriatrics; Humans; Mechlorethamine; Melphalan; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Pharmacology; Thiotepa; Toxicology; Triethylenemelamine; Vinblastine; Vincristine | 1964 |
CHEMOTHERAPY STUDIES WITH VIRUS-INDUCED LEUKEMIA IN MICE.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Leukemia; Leukemia, Experimental; Melphalan; Mercaptopurine; Mice; Neoplasms; Neoplasms, Experimental; Oncogenic Viruses; Pharmacology; Research; Triethylenemelamine | 1964 |
INTERACTION BETWEEN 5-HYDROXYTRYPTAMINE AND ANTITUMOURAL DRUGS.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Fluorouracil; Melphalan; Mice; Mitomycin; Mitomycins; Nitrogen Mustard Compounds; Pharmacology; Research; Sarcoma 180; Serotonin; Toxicology; Triethylenemelamine | 1964 |
Significance of postoperative adjuvant immunochemotherapy after curative resection of colorectal cancers: identification of responders incorporating the age factor.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Carcinoembryonic Antigen; Chemotherapy, Adjuvant; Colonic Neoplasms; Complement C3; Complement C4; Female; Fluorouracil; Humans; Immunotherapy; Lymphocyte Activation; Male; Medroxyprogesterone Acetate; Melphalan; Middle Aged; Mitomycin; Multivariate Analysis; Neoplasm Proteins; Phytohemagglutinins; Prognosis; Proportional Hazards Models; Proteoglycans; Pyrimidines; Time Factors; Treatment Outcome | 2004 |
In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the tumor.
Topics: Animals; Antineoplastic Agents; Apoptosis; BRCA2 Protein; Caspases; Cell Cycle; Cell Line, Tumor; Cell Survival; Chlorambucil; Cisplatin; Cross-Linking Reagents; Deoxycytidine; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Fanconi Anemia Complementation Group C Protein; Fanconi Anemia Complementation Group G Protein; Fanconi Anemia Complementation Group Proteins; Female; Fluorouracil; Gemcitabine; Humans; Inhibitory Concentration 50; Melphalan; Mice; Mice, Nude; Mitomycin; Mutation; Paclitaxel; Pancreatic Neoplasms; Time Factors; Vinblastine; Xenograft Model Antitumor Assays | 2005 |
Chemoradiotherapy in patients with anal cancer: impact of length of unplanned treatment interruption on outcome.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cyclophosphamide; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Male; Melphalan; Middle Aged; Radiotherapy Dosage; Retrospective Studies; Semustine; Time Factors; Treatment Outcome | 2006 |
Heterogeneous activity of cytotoxic drugs in patient samples of peritoneal carcinomatosis.
Topics: Camptothecin; Cisplatin; Cytotoxins; Doxorubicin; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Irinotecan; Male; Melphalan; Mitomycin; Organoplatinum Compounds; Oxaliplatin; Perioperative Care; Peritoneal Neoplasms; Tumor Cells, Cultured | 2008 |
Hepatoblastoma presenting with focal nodular hyperplasia after treatment of neuroblastoma.
Topics: Adrenal Gland Neoplasms; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carboplatin; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Etoposide; Fluorouracil; Focal Nodular Hyperplasia; Granulocyte Colony-Stimulating Factor; Hepatectomy; Hepatoblastoma; Humans; Ifosfamide; Immunoglobulin G; Incidental Findings; Liver Neoplasms; Male; Melphalan; Mesna; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Neuroblastoma; Radiotherapy, Adjuvant; Tomography, X-Ray Computed; Vincristine | 2008 |
Failure event types and prognostic factors after node-positive breast cancer in patients treated by adjuvant chemotherapy: impact on follow-up.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Docetaxel; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymph Nodes; Melphalan; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Prognosis; Randomized Controlled Trials as Topic; Taxoids; Treatment Failure | 2012 |
Hydrolyzable tannins of tamaricaceous plants. V. Structures of monomeric-trimeric tannins and cytotoxicity of macrocyclic-type tannins isolated from Tamarix nilotica (1).
Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Egypt; Fluorouracil; Humans; Hydrolyzable Tannins; Melphalan; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Polyphenols; Tamaricaceae | 2013 |
Potential Benefits of Oral Cryotherapy for Chemotherapy-Induced Mucositis.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cryotherapy; Female; Fluorouracil; Humans; Ice; Male; Melphalan; Middle Aged; Mucositis; Neoplasms | 2016 |
Repurposing the anticancer drug mitomycin C for the treatment of persistent Acinetobacter baumannii infections.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Cisplatin; Disease Models, Animal; Drug Repositioning; Fluorouracil; Larva; Lepidoptera; Melphalan; Microbial Sensitivity Tests; Microbial Viability; Mitomycin; Survival Analysis; Treatment Outcome | 2017 |
Hepatic arterial infusion chemotherapy for extensive liver metastases of breast cancer: efficacy, safety and prognostic parameters.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Melphalan; Middle Aged; Mitomycin; Retrospective Studies; Salvage Therapy | 2017 |
Exploration on the drug solubility enhancement in aqueous medium with the help of endo-functionalized molecular tubes: a computational approach.
Topics: Albendazole; Camptothecin; Clopidogrel; Drug Industry; Fluorouracil; Indomethacin; Melphalan; Molecular Dynamics Simulation; ortho-Aminobenzoates; Solubility; Water | 2021 |