fluorouracil and mannitol

fluorouracil has been researched along with mannitol in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199011 (42.31)18.7374
1990's2 (7.69)18.2507
2000's9 (34.62)29.6817
2010's3 (11.54)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Levin, VA1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Blau, HJ1
Pruemer, JM; Wermeling, JR; Woloschuk, DM1
Hosoya, T; Nakai, O; Takahama, H; Takanashi, T; Yamada, K1
Shapiro, JR; Shapiro, WR1
Dimery, IW; Legha, SS1
Fukui, M; Inoue, T; Kitamura, K; Nagara, H; Nishio, S1
Galletti, PM; Madonia, S; Pasqualino, A; Pavone-Macaluso, M1
Barnett, PA; Frenkel, EP; Glasberg, M; Neuwelt, EA1
Barnett, P; Frenkel, E; Glasberg, M; Neuwelt, EA1
Docker, M; Irwin, WJ; Meidan, VM; Walmsley, AD1
Brátová, M; Kohout, P; Králícková, P; Melichar, B; Solichová, D; Zadák, Z1
CHAKRAVORTY, M1
BERRY, RJ1
Barry, BW; El Maghraby, GM; Williams, AC1
Akhurst, LC; Bertens, A; Botta, A; Cinelli, S; Clare, MG; Lorenzon, G; Lorge, E; Marzin, D; Montero, R; Thybaud, V; van Delft, J1
Araki, H; Hamada, S; Itoh, S; Kobayashi, K; Kubo, K; Lorenzon, G; Lorge, E; Marzin, D; Matsui, A; Matsuoka, A; Miyajima, H; Nishida, S; Senjyu, N; Thybaud, V; Wakata, A; Yamakage, K; Yamamura, E; Yoshida, J1
Awogi, T; Bichet, N; Elhajouji, A; Lorenzon, G; Lorge, E; Marzin, D; Meunier, JR; Oliver, J; Ouldelhkim, MC; Thybaud, V1
Aardema, MJ; Lorenzon, G; Lorge, E; Marzin, D; Oliver, J; Thybaud, V; Wakata, A1
Campanella, G; Clemente, C; D'Attoma, B; Giotta, F; Linsalata, M; Orlando, A; Riezzo, G; Russo, F1
Cano-Cebrián, MJ; Dahlgren, D; Kullenberg, F; Lennernäs, H; Olander, T; Peters, K; Sjöblom, M1

Reviews

2 review(s) available for fluorouracil and mannitol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Principles of brain tumor chemotherapy.
    Seminars in oncology, 1986, Volume: 13, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Carbon Radioisotopes; Carmustine; Cell Line; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance; Fluorouracil; Glioma; Humans; Hydroxyurea; Infusions, Intra-Arterial; Karyotyping; Kinetics; Mannitol; Methotrexate; Podophyllotoxin; Procarbazine; Rats; Tumor Stem Cell Assay

1986

Trials

2 trial(s) available for fluorouracil and mannitol

ArticleYear
Sequential methotrexate, 5-fluorouracil, and cisplatin in the treatment of recurrent squamous-cell carcinoma of the head and neck: failure of hypertonic saline to reduce the nephrotoxicity of cisplatin.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kidney Diseases; Male; Mannitol; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Random Allocation; Sodium Chloride

1986
The effects of fluorouracil, epirubicin, and cyclophosphamide (FEC60) on the intestinal barrier function and gut peptides in breast cancer patients: an observational study.
    BMC cancer, 2013, Feb-04, Volume: 13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Cholera Toxin; Cyclophosphamide; Diarrhea; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; Epirubicin; Female; Fluorouracil; Ghrelin; Glucagon-Like Peptide 2; Haptoglobins; Humans; Intestinal Absorption; Intestinal Mucosa; Italy; Lactulose; Mannitol; Middle Aged; Peptides; Permeability; Prospective Studies; Protein Precursors; Stomatitis; Time Factors; Treatment Outcome

2013

Other Studies

22 other study(ies) available for fluorouracil and mannitol

ArticleYear
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Male; Models, Biological; Molecular Weight; Rats; Rats, Inbred F344; Solubility; Structure-Activity Relationship

1980
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
[Side effects of cytostatic therapy in childhood].
    Kinderarztliche Praxis, 1976, Volume: 44, Issue:6

    Topics: Adolescent; Antineoplastic Agents; Asparaginase; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Female; Fluorouracil; Humans; Male; Mannitol; Mercaptopurine; Methotrexate; Prednisone; Procarbazine; Time Factors; Triaziquone; Vinblastine; Vincristine

1976
Stability and compatibility of fluorouracil and mannitol during simulated Y-site administration.
    American journal of hospital pharmacy, 1991, Volume: 48, Issue:10

    Topics: Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Incompatibility; Drug Stability; Fluorouracil; Glucose; Infusions, Intravenous; Mannitol; Sodium Chloride

1991
[Intra-arterial chemotherapy of malignant glioma after osmotic blood-brain barrier disruption].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Evaluation Studies as Topic; Female; Fluorouracil; Glioma; Humans; Infusions, Intra-Arterial; Interferon Type I; Leukopenia; Male; Mannitol; Middle Aged; Nimustine; Osmotic Pressure; Remission Induction; Thrombocytopenia

1989
Hyperosmotic blood-brain barrier disruption in brains of rats with an intracerebrally transplanted RG-C6 tumor.
    Journal of neurosurgery, 1987, Volume: 66, Issue:2

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Evans Blue; Fluorouracil; Glioma; Horseradish Peroxidase; Hypertonic Solutions; Infusions, Intra-Arterial; Male; Mannitol; Rats; Rats, Inbred Strains

1987
[Forced diuresis, peritoneal dialysis, central hemodialysis and peripheral hemodialysis in protection from the toxic effects of 5-fluororuracil].
    Minerva medica, 1969, Feb-24, Volume: 60, Issue:16

    Topics: Animals; Diuresis; Dogs; Fluorouracil; Infusions, Parenteral; Mannitol; Peritoneal Dialysis; Renal Dialysis

1969
Pharmacology and neurotoxicity of cis-diamminedichloroplatinum, bleomycin, 5-fluorouracil, and cyclophosphamide administration following osmotic blood-brain barrier modification.
    Cancer research, 1983, Volume: 43, Issue:11

    Topics: Animals; Bleomycin; Blood-Brain Barrier; Brain; Cisplatin; Cyclophosphamide; Dogs; Fluorouracil; Mannitol; Neurotoxins; Rats; Rats, Inbred Strains; Seizures

1983
Neurotoxicity of chemotherapeutic agents after blood-brain barrier modification: neuropathological studies.
    Annals of neurology, 1983, Volume: 14, Issue:3

    Topics: Animals; Antineoplastic Agents; Bleomycin; Blood-Brain Barrier; Brain; Cisplatin; Cyclophosphamide; Dogs; Dose-Response Relationship, Drug; Doxorubicin; Fluorouracil; Injections, Intra-Arterial; Injections, Intravenous; Mannitol

1983
Low intensity ultrasound as a probe to elucidate the relative follicular contribution to total transdermal absorption.
    Pharmaceutical research, 1998, Volume: 15, Issue:1

    Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Biological Transport; Diuretics, Osmotic; Fluorouracil; Hydrocortisone; Mannitol; Rats; Skin Absorption; Sonication; Sucrose

1998
Intestinal permeability in patients with chemotherapy-induced stomatitis.
    Journal of cancer research and clinical oncology, 2001, Volume: 127, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Digestive System Neoplasms; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Gemcitabine; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Intestinal Absorption; Intestinal Mucosa; Lactulose; Leucovorin; Male; Mannitol; Middle Aged; Paclitaxel; Permeability; Stomatitis; Tegafur; Treatment Outcome; Xylose

2001
INDUCTION AND REPRESSION OF L-ARABINOSE ISOMERASE IN LACTOBACILLUS PLANTARUM.
    Biochimica et biophysica acta, 1964, Apr-06, Volume: 85

    Topics: Aldose-Ketose Isomerases; Arabinose; Carbohydrate Metabolism; Culture Media; Dactinomycin; Enzyme Inhibitors; Fluorouracil; Fructose; Genetics; Glucose; Glucuronates; Glycerol; Isomerases; Lactobacillus; Lactobacillus plantarum; Mannitol; Mannose; Pharmacology; Research; Spectrophotometry; Toluene; Xylose

1964
A COMPARISON OF EFFECTS OF SOME CHEMOTHERAPEUTIC AGENTS AND THOSE OF X-RAYS ON THE REPRODUCTIVE CAPACITY OF MAMMALIAN CELLS.
    Nature, 1964, Sep-12, Volume: 203

    Topics: Animals; Antineoplastic Agents; Cell Division; Ethers; Ethers, Cyclic; Ethoglucid; Fibroblasts; Fluorouracil; Mannitol; Mannomustine; Mechlorethamine; Pharmacology; Research; Thiotepa; Tissue Culture Techniques; X-Rays

1964
Drug interaction and location in liposomes: correlation with polar surface areas.
    International journal of pharmaceutics, 2005, Mar-23, Volume: 292, Issue:1-2

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Drug Design; Drug Interactions; Estradiol; Fluorouracil; Hydrophobic and Hydrophilic Interactions; Inulin; Liposomes; Mannitol; Oligonucleotides, Antisense; Solubility; Surface Properties; Water

2005
SFTG international collaborative study on in vitro micronucleus test II. Using human lymphocytes.
    Mutation research, 2006, Aug-04, Volume: 607, Issue:1

    Topics: Adult; Aneugens; Bleomycin; Clofibrate; Colchicine; Cytarabine; Diethylstilbestrol; Female; Fluorouracil; Humans; In Vitro Techniques; International Cooperation; Lymphocytes; Male; Mannitol; Micronucleus Tests; Mutagens; Thiabendazole; Urethane

2006
SFTG international collaborative study on in vitro micronucleus test IV. Using CHL cells.
    Mutation research, 2006, Aug-04, Volume: 607, Issue:1

    Topics: Aneugens; Animals; Bleomycin; Cell Line; Clofibrate; Colchicine; Cricetinae; Cytarabine; Cytochalasin B; Diethylstilbestrol; Fluorouracil; Griseofulvin; In Vitro Techniques; International Cooperation; Mannitol; Micronucleus Tests; Mutagens; Urethane

2006
SFTG international collaborative study on in vitro micronucleus test V. Using L5178Y cells.
    Mutation research, 2006, Aug-04, Volume: 607, Issue:1

    Topics: Aneugens; Animals; Bleomycin; Colchicine; Fluorouracil; Griseofulvin; In Vitro Techniques; International Cooperation; Leukemia L5178; Mannitol; Mice; Micronucleus Tests; Mutagens

2006
SFTG international collaborative study on in vitro micronucleus test I. General conditions and overall conclusions of the study.
    Mutation research, 2006, Aug-04, Volume: 607, Issue:1

    Topics: Aneugens; Animals; Bleomycin; Cell Line; CHO Cells; Clofibrate; Colchicine; Cricetinae; Cytarabine; Cytochalasin B; Diethylstilbestrol; Fluorouracil; Griseofulvin; Humans; In Vitro Techniques; International Cooperation; Leukemia L5178; Lymphocytes; Mannitol; Mice; Micronucleus Tests; Mitomycin; Mutagens; Thiabendazole

2006
Chemotherapeutics Combined with Luminal Irritants: Effects on Small-Intestinal Mannitol Permeability and Villus Length in Rats.
    International journal of molecular sciences, 2022, Jan-18, Volume: 23, Issue:3

    Topics: Animals; Doxycycline; Ethanol; Fluorouracil; Injections, Intraperitoneal; Intestinal Mucosa; Irinotecan; Irritants; Male; Mannitol; Mucositis; Organ Size; Permeability; Rats; Sodium Dodecyl Sulfate

2022