fluorouracil has been researched along with lidocaine in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (7.14) | 18.2507 |
| 2000's | 14 (50.00) | 29.6817 |
| 2010's | 11 (39.29) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Hansch, C; Khwaja, TA; Selassie, CD | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Bertolissi, A; Cartei, G; Cioschi, B; Marsilio, P; Rizzi, V; Tabaro, G | 1 |
| Aydemir, EH; Engin, B; Göksügür, N; Isçimen, A | 1 |
| Fang, L; He, Z; Xu, Y; Zhao, L; Zhao, Y | 1 |
| Fang, L; He, Z; Liu, S; Xu, Y; Zhao, L; Zhao, Y | 1 |
| Farshchian, M; Fereydoonnejad, M; Yazdanfar, A | 1 |
| Balaji, KC; Gammon, DC; Patel, M; Reed, KA | 1 |
| Gao, Z; Liu, W; Song, N; Wu, X | 1 |
| Gauthier-Hazan, N; Lemperle, G | 1 |
| Goto, T; Harano, N; Hitomi, S; Inenaga, K; Inoue, H; Ito, M; Matoba, M; Miyano, K; Nodai, T; Ono, K; Uezono, Y; Watanabe, S; Yamaguchi, K | 1 |
| Huang, S; Liu, W; Wang, Y; Xie, J; Xing, Y; Zhang, R | 1 |
| Liu, H; Pang, W; Wang, J; Zhang, X | 1 |
| Bagheri, Z; Sarani, MB; Sepaskhah, M | 1 |
2 review(s) available for fluorouracil and lidocaine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Foreign body granulomas after all injectable dermal fillers: part 2. Treatment options.
Topics: Anesthetics, Local; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Betamethasone; Dermis; Drug Therapy, Combination; Female; Fluorouracil; Granuloma, Foreign-Body; Humans; Injections; Lidocaine; Methylprednisolone; Minocycline; Triamcinolone | 2009 |
4 trial(s) available for fluorouracil and lidocaine
| Article | Year |
|---|---|
Liver function tests and lidocaine metabolism (MEGX test) during i.v. CMF therapy in breast cancer.
Topics: Adult; Aged; Anesthetics, Local; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Fluorouracil; Humans; Lidocaine; Liver Function Tests; Methotrexate; Middle Aged; Prospective Studies | 1996 |
Intralesional 5-fluorouracil, lidocaine and epinephrine mixture for the treatment of verrucae: a prospective placebo-controlled, single-blind randomized study.
Topics: Adolescent; Adult; Anesthetics, Local; Antimetabolites; Drug Combinations; Epinephrine; Fluorouracil; Humans; Injections, Intralesional; Lidocaine; Middle Aged; Recurrence; Single-Blind Method; Vasoconstrictor Agents; Warts | 2004 |
Treatment of common warts with an intralesional mixture of 5-fluorouracil, lidocaine, and epinephrine: a prospective placebo-controlled, double-blind randomized trial.
Topics: Adolescent; Adult; Antimetabolites; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Female; Fluorouracil; Humans; Injections, Intralesional; Lidocaine; Male; Prospective Studies; Treatment Outcome; Warts | 2008 |
Comparison of the efficacy of intralesional 5-fluorouracil/lidocaine/epinephrine injection with cryotherapy to treat common and palmoplantar warts: A randomized, controlled trial.
Topics: Cryotherapy; Epinephrine; Fluorouracil; Humans; Injections, Intralesional; Lidocaine; Pain; Quality of Life; Treatment Outcome; Warts | 2022 |
22 other study(ies) available for fluorouracil and lidocaine
| Article | Year |
|---|---|
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Effect of O-acylmenthol on transdermal delivery of drugs with different lipophilicity.
Topics: Acids, Carbocyclic; Administration, Cutaneous; Animals; Chemistry, Pharmaceutical; Cinnamates; Diffusion Chambers, Culture; Drug Compounding; Fluorouracil; Hydrolysis; Indomethacin; Isosorbide Dinitrate; Ketoprofen; Kinetics; Lactates; Lidocaine; Male; Menthol; Oleic Acids; Permeability; Pharmaceutical Preparations; Rats; Rats, Wistar; Salicylates; Skin; Skin Absorption; Technology, Pharmaceutical | 2008 |
Transdermal delivery of penetrants with differing lipophilicities using O-acylmenthol derivatives as penetration enhancers.
Topics: Administration, Cutaneous; Animals; Chemistry, Pharmaceutical; Fatty Acids; Fluorouracil; Indomethacin; Isosorbide Dinitrate; Ketoprofen; Lidocaine; Male; Menthol; Rats; Rats, Wistar; Skin Absorption; Technology, Pharmaceutical | 2008 |
Intraurethral fluorouracil and lidocaine for intraurethral condyloma acuminata.
Topics: Administration, Topical; Anesthetics, Local; Condylomata Acuminata; Drug Therapy, Combination; Fluorouracil; Gels; Humans; Lidocaine; Male; Middle Aged; Papillomaviridae; Papillomavirus Infections; Urethral Diseases | 2008 |
Remodelling of keloid tissue into normal-looking skin.
Topics: Anesthetics, Local; Antimetabolites; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Glucocorticoids; Humans; Keloid; Lidocaine; Middle Aged; Triamcinolone Acetonide | 2008 |
Distinct TRPV1- and TRPA1-based mechanisms underlying enhancement of oral ulcerative mucositis-induced pain by 5-fluorouracil.
Topics: Acetanilides; Anesthetics, Local; Animals; Anti-Bacterial Agents; Antimetabolites; Carcinosarcoma; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Eating; Fluorouracil; Hyperalgesia; Leukocytes; Lidocaine; Male; Microbial Viability; Pain; Pain Management; Polymyxin B; Purines; Rats; Rats, Wistar; Stomatitis; Trigeminal Ganglion; TRPV Cation Channels | 2016 |
Lidocaine sensitizes the cytotoxicity of 5-fluorouacil in melanoma cells
Topics: Anesthetics, Local; Antimetabolites, Antineoplastic; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Lidocaine; Melanoma; MicroRNAs; Phosphatidylinositol 3-Kinase; Polymerase Chain Reaction; Proto-Oncogene Proteins c-akt; Smad Proteins; SOXC Transcription Factors; Up-Regulation | 2017 |
Lidocine potentiates the cytotoxicity of 5-fluorouracil to choriocarcinoma cells by downregulating ABC transport proteins expression.
Topics: ATP-Binding Cassette Transporters; Cell Line, Tumor; Choriocarcinoma; Cytotoxins; Down-Regulation; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Lidocaine; Neoplasm Proteins | 2019 |