fluorouracil and interleukin-8

fluorouracil has been researched along with interleukin-8 in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (30.43)29.6817
2010's11 (47.83)24.3611
2020's5 (21.74)2.80

Authors

AuthorsStudies
Arun, B; Booser, D; Bruera, E; Cleeland, CS; Fritsche, HA; Hortobagyi, GN; Ibrahim, N; Lara, J; Martinez, MM; Mendoza, TR; Pusztai, L; Reuben, JM; Rivera, E; Royce, M; Syed, A; Valero, V; Willey, JS1
Ashida, Y; Azuma, M; Harada, K; Kawaguchi, S; Motegi, K; Sato, M; Takashima, R; Tamatani, T1
Fujimoto, T; Ishibashi, K; Kobayashi, R; Ogawa, K; Umehara, A; Watanabe, K; Yokomizo, H; Yoshida, K; Yoshimatsu, K1
Borchard, E; Gil, J; Gordon, M; Groshen, S; Lenz, HJ; Park, DJ; Press, OA; Rhodes, K; Stoehlmacher, J; Tsao-Wei, DD; Yang, D; Yun, J; Zhang, W1
Abdel-Latif, MM; Kelleher, D; O'Riordan, JM; Ravi, N; Reynolds, JV1
Cunha, FQ; Mendonça, MA; Murta, EF; Tavares-Murta, BM1
Chang, HM; Gordon, MA; Groshen, S; Hendifar, AE; Husain, H; Lenz, HJ; Lurje, G; Nagashima, F; Schultheis, AM; Yang, D; Zhang, W1
Chang, SC; Chiou, SH; Hwang, WL; Lan, HY; Lan, YT; Su, SH; Teng, HW; Tsai, ML; Wang, HW; Yang, MH; Yang, SH1
Cunha, FQ; Franco, AX; Justino, PF; Mota, JM; Ribeiro, RA; Soares, PM; Souza, EP; Souza, MH1
Andratschke, M; Maushagen, R; Pfannerstill, AC; Pries, R; Rades, D; Reers, S; Wollenberg, B1
Alves-Filho, JC; Cunha, FQ; Mendonça, MA; Micheli, DC; Murta, EF; Souto, FO; Tavares-Murta, BM1
Cui, A; Cui, L; Hu, X; Liang, Z; Liu, CY; Liu, Y; Mei, Z; Wang, G; Wang, Z; Wu, T; Yang, Y1
Chiron, M; Folprecht, G; Lambrechts, D; Margherini, E; Moisse, M; Pericay, C; Peuteman, G; Sagaert, X; Thienpont, B; Thuillier, V; Van Cutsem, E; Zalcberg, J; Zilocchi, C1
Dabkeviciene, D; Grigaitis, P; Jonusiene, V; Kirveliene, V; Sasnauskiene, A; Zalyte, E; Zitkute, V1
Jin, DY; Lou, WH; Rong, YF; Wu, W; Xu, XF; Zhang, L1
Bosserhoff, AK; Freese, K; Hellerbrand, C; Kuecuekoktay, FS; Mahli, A; Müller, M; Schiergens, TS; Sommer, J; Teufel, A; Thasler, WE1
Barone, C; Basso, M; Berenato, R; Bossi, I; Capoluongo, E; Caporale, M; Danesi, R; de Braud, F; Del Re, M; Di Salvatore, M; Guarino, D; Martinetti, A; Mennitto, A; Mennitto, R; Orlandi, A; Pietrantonio, F; Rossi, E; Santonocito, C; Schinzari, G1
Chiron, M; Denda, T; Esaki, T; Fujii, H; Hamaguchi, T; Itabashi, M; Kajiwara, T; Komatsu, Y; Kudo, T; Moriwaki, T; Nagashima, F; Nakajima, TE; Oki, E; Otsu, S; Sasaki, T; Sato, T; Sugimoto, N; Takahashi, S; Ura, T; Yamazaki, K; Yoshino, T1
Ding, S; Jiang, Y; Luo, P; Qing, B; Tang, R; Tang, Z; Wei, Y; Zhang, S1
Csikó, G; Erdélyi, B; Palócz, O; Sátorhelyi, P1
Kanamura, N; Kishimoto, S; Mazda, O; Nakai, K; Oseko, F; Yamamoto, K; Yamamoto, T; Yamanobe, H1
Abe, Y; Asano, C; Bando, H; Denda, T; Esaki, T; Kagawa, Y; Kato, T; Kawakami, H; Matsuhashi, N; Nishina, T; Nomura, S; Satake, H; Shiozawa, M; Sunakawa, Y; Takahashi, N; Takashima, A; Taniguchi, H; Yamazaki, K; Yasui, H; Yoshino, T; Yuki, S1
Aleksandraviciute, B; Eidenaite, E; Jasinevicius, A; Jonusiene, V; Kukcinaviciute, E; Sasnauskiene, A; Sudeikis, L; Vaitiekaite, G; Zitkute, V1

Trials

2 trial(s) available for fluorouracil and interleukin-8

ArticleYear
Changes in plasma levels of inflammatory cytokines in response to paclitaxel chemotherapy.
    Cytokine, 2004, Feb-07, Volume: 25, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Blood; Breast Neoplasms; Cyclophosphamide; Cytokines; Data Interpretation, Statistical; Doxorubicin; Fatigue; Female; Fluorouracil; Humans; Interleukin-1; Interleukin-10; Interleukin-12; Interleukin-6; Interleukin-8; Middle Aged; Nausea; Paclitaxel; Pain; Patient Selection; Quality of Life; Tumor Necrosis Factor-alpha

2004
Evaluation of efficacy and safety markers in a phase II study of metastatic colorectal cancer treated with aflibercept in the first-line setting.
    British journal of cancer, 2015, Sep-29, Volume: 113, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Colorectal Neoplasms; Female; Fluorouracil; Humans; Interleukin-8; Leucovorin; Male; Middle Aged; Mutation; Neoplasm Metastasis; Organoplatinum Compounds; Polymorphism, Single Nucleotide; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Survival Analysis; Treatment Outcome; Vascular Endothelial Growth Factor B

2015

Other Studies

21 other study(ies) available for fluorouracil and interleukin-8

ArticleYear
Enhanced radiosensitization and chemosensitization in NF-kappaB-suppressed human oral cancer cells via the inhibition of gamma-irradiation- and 5-FU-induced production of IL-6 and IL-8.
    International journal of cancer, 2004, Mar-01, Volume: 108, Issue:6

    Topics: Animals; Annexin A5; Antimetabolites, Antineoplastic; Apoptosis; Blotting, Western; Carcinoma; Cell Division; Cell Nucleus; Cell Separation; Culture Media, Conditioned; Cytosol; DNA, Complementary; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluorouracil; Gamma Rays; Genetic Vectors; Humans; I-kappa B Proteins; Immunohistochemistry; Interleukin-6; Interleukin-8; Luciferases; Matrix Metalloproteinase 9; Mice; Mice, Nude; Mouth Neoplasms; Mutation; Neovascularization, Pathologic; NF-kappa B; NF-KappaB Inhibitor alpha; Oligonucleotides; Time Factors; Transfection; Vascular Endothelial Growth Factor A

2004
[Host immunity in colorectal cancer patients treated with low-dose Leucovorin plus 5-fluorouracil].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Interleukin-10; Interleukin-8; Leucovorin; Lymphocyte Activation; Male; Middle Aged; Phytohemagglutinins; Receptors, Interleukin-2; Th1 Cells; Th2 Cells; Time Factors

2004
Gene polymorphisms of epidermal growth factor receptor and its downstream effector, interleukin-8, predict oxaliplatin efficacy in patients with advanced colorectal cancer.
    Clinical colorectal cancer, 2005, Volume: 5, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Fluorouracil; Genes, erbB-1; Humans; Interleukin-8; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Polymorphism, Restriction Fragment Length; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Risk; Survival Rate

2005
Activated nuclear factor-kappa B and cytokine profiles in the esophagus parallel tumor regression following neoadjuvant chemoradiotherapy.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2005, Volume: 18, Issue:4

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Chemotherapy, Adjuvant; Cisplatin; Down-Regulation; Epithelium; Esophageal Neoplasms; Esophagectomy; Esophagus; Female; Fluorouracil; Humans; Interleukin-1; Interleukin-8; Male; Neoadjuvant Therapy; NF-kappa B; Radiotherapy Dosage; Radiotherapy, Adjuvant; Remission Induction

2005
Failure of neutrophil chemotactic function in breast cancer patients treated with chemotherapy.
    Cancer chemotherapy and pharmacology, 2006, Volume: 57, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Case-Control Studies; Cell Movement; Chemotaxis, Leukocyte; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Interleukin-10; Interleukin-6; Interleukin-8; Leukocyte Count; Leukotriene B4; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neoadjuvant Therapy; Neutrophils; Nitric Oxide; Prospective Studies; Tumor Necrosis Factor-alpha

2006
Polymorphisms in VEGF and IL-8 predict tumor recurrence in stage III colon cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; DNA, Neoplasm; Female; Fluorouracil; Humans; Interleukin-8; Male; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Neoplasm Staging; Neovascularization, Pathologic; Polymorphism, Genetic; Retrospective Studies; Vascular Endothelial Growth Factor A

2008
SNAIL regulates interleukin-8 expression, stem cell-like activity, and tumorigenicity of human colorectal carcinoma cells.
    Gastroenterology, 2011, Volume: 141, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antibodies; Antigens, CD; Antimetabolites, Antineoplastic; Binding Sites; Carcinoma; Cell Adhesion Molecules, Neuronal; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Resistance, Neoplasm; E-Box Elements; Epithelial-Mesenchymal Transition; Fetal Proteins; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Hyaluronan Receptors; Interleukin-8; Mice; Mice, Nude; Middle Aged; Neoplastic Stem Cells; Oligonucleotide Array Sequence Analysis; Radiation Tolerance; Signal Transduction; Snail Family Transcription Factors; Spheroids, Cellular; Time Factors; Transcription Factors; Transfection; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2011
Inflammatory intestinal damage induced by 5-fluorouracil requires IL-4.
    Cytokine, 2013, Volume: 61, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Duodenum; Fluorouracil; Interleukin-1beta; Interleukin-4; Interleukin-8; Intestinal Mucosa; Intestines; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucositis; Tumor Necrosis Factor-alpha

2013
Cytokine changes in response to radio-/chemotherapeutic treatment in head and neck cancer.
    Anticancer research, 2013, Volume: 33, Issue:6

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Fluorouracil; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Head and Neck Neoplasms; Humans; Interleukin-1beta; Interleukin-6; Interleukin-8; Th1-Th2 Balance; Tumor Microenvironment; Tumor Necrosis Factor-alpha

2013
Mechanisms affecting neutrophil migration capacity in breast cancer patients before and after chemotherapy.
    Cancer chemotherapy and pharmacology, 2014, Volume: 73, Issue:2

    Topics: Actins; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Case-Control Studies; Cell Movement; Cyclophosphamide; Cytokines; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Immune System Diseases; Interleukin-8; Leukocyte Disorders; Middle Aged; Neutrophils; Nitric Oxide; Receptors, CXCR

2014
Interleukin 22 protects colorectal cancer cells from chemotherapy by activating the STAT3 pathway and inducing autocrine expression of interleukin 8.
    Clinical immunology (Orlando, Fla.), 2014, Volume: 154, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Autocrine Communication; Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Interleukin-22; Interleukin-8; Interleukins; Leucovorin; Organoplatinum Compounds; STAT3 Transcription Factor; Treatment Failure

2014
The role of interleukin-8 (CXCL8) and CXCR2 in acquired chemoresistance of human colorectal carcinoma cells HCT116.
    Medical oncology (Northwood, London, England), 2015, Volume: 32, Issue:12

    Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Fluorouracil; HCT116 Cells; Humans; Interleukin-1alpha; Interleukin-8; Organoplatinum Compounds; Oxaliplatin; Real-Time Polymerase Chain Reaction; Receptors, Interleukin-8B; Signal Transduction

2015
SN38 increases IL-8 expression through the MAPK pathways in HCT8 cells.
    International journal of molecular medicine, 2017, Volume: 39, Issue:1

    Topics: Berberine; Camptothecin; Cell Line, Tumor; Cell Survival; Fluorouracil; Humans; Interleukin-8; Irinotecan; Janus Kinase 2; MAP Kinase Signaling System; Phosphorylation; Quinazolines; Up-Regulation

2017
Analysis of molecular mechanisms of 5-fluorouracil-induced steatosis and inflammation in vitro and in mice.
    Oncotarget, 2017, Feb-21, Volume: 8, Issue:8

    Topics: Acyl-CoA Oxidase; Animals; Antimetabolites, Antineoplastic; Blotting, Western; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Fatty Liver; Female; Fluorouracil; Gene Expression; Heme Oxygenase-1; Hep G2 Cells; Hepatocytes; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Liver; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction; Triglycerides

2017
IL-8 and eNOS polymorphisms predict bevacizumab-based first line treatment outcomes in RAS mutant metastatic colorectal cancer patients.
    Oncotarget, 2017, Mar-07, Volume: 8, Issue:10

    Topics: Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Cohort Studies; Colorectal Neoplasms; Female; Fluorouracil; Humans; Interleukin-8; Leucovorin; Male; Mutation; Neoplasm Metastasis; Nitric Oxide Synthase Type III; Organoplatinum Compounds; Polymorphism, Single Nucleotide; ras Proteins; Treatment Outcome

2017
Exploration of potential prognostic biomarkers in aflibercept plus FOLFIRI in Japanese patients with metastatic colorectal cancer.
    Cancer science, 2019, Volume: 110, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asian People; Biomarkers, Tumor; Camptothecin; Colonic Neoplasms; Fluorouracil; Humans; Insulin-Like Growth Factor Binding Protein 1; Interleukin-8; Japan; Kallikreins; Leucovorin; Placenta Growth Factor; Prognosis; Progression-Free Survival; Prospective Studies; Pulmonary Surfactant-Associated Protein D; Receptor for Advanced Glycation End Products; Receptors, Tumor Necrosis Factor, Type II; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Rectal Neoplasms; Regression Analysis; Tenascin; Tissue Inhibitor of Metalloproteinase-1; Vascular Endothelial Growth Factor Receptor-1

2019
HDAC1 regulates the chemosensitivity of laryngeal carcinoma cells via modulation of interleukin-8 expression.
    European journal of pharmacology, 2021, Apr-05, Volume: 896

    Topics: 3' Untranslated Regions; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Histone Deacetylase 1; Humans; Interleukin-8; Laryngeal Neoplasms; Signal Transduction; Squamous Cell Carcinoma of Head and Neck

2021
Impact of heat-inactivated Lactobacillus on inflammatory response in endotoxin- and chemotherapeutic-treated porcine enterocytes.
    Research in veterinary science, 2023, Volume: 154

    Topics: Animals; Endotoxins; Enterocytes; Fluorouracil; Hot Temperature; Interleukin-6; Interleukin-8; Intestinal Mucosa; Lactobacillus; Lipopolysaccharides; Probiotics; Swine

2023
Anti-Inflammatory Effects of β-Cryptoxanthin on 5-Fluorouracil-Induced Cytokine Expression in Human Oral Mucosal Keratinocytes.
    Molecules (Basel, Switzerland), 2023, Mar-24, Volume: 28, Issue:7

    Topics: Anti-Inflammatory Agents; Beta-Cryptoxanthin; Cytokines; Fluorouracil; Humans; Interleukin-6; Interleukin-8; Keratinocytes; Lipopolysaccharides; Matrix Metalloproteinase 9; Quality of Life; RNA, Messenger; Stomatitis

2023
Role of plasma angiogenesis factors in the efficacy of first-line chemotherapy combined with biologics in RAS wild-type metastatic colorectal cancer: Results from the GI-SCREEN CRC-Ukit study.
    Cancer medicine, 2023, Volume: 12, Issue:18

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biological Products; Biomarkers; Colonic Neoplasms; Colorectal Neoplasms; Fluorouracil; Humans; Interleukin-8; Rectal Neoplasms; Vascular Endothelial Growth Factor A

2023
The role of p62 in cell death and survival of 5-fluorouracil and oxaliplatin-resistant colorectal cancer cells.
    Journal of cellular biochemistry, 2023, Volume: 124, Issue:11

    Topics: Apoptosis; Cell Death; Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; Oxaliplatin

2023