fluorouracil and hypoxanthine

fluorouracil has been researched along with hypoxanthine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's3 (27.27)18.2507
2000's2 (18.18)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, TL; Erlichman, C1
Nagai, M; Nakamura, H; Olah, E; Prajda, N; Szekeres, T; Weber, G1
Laurensse, E; Leyva, A; Peters, GJ; Pinedo, HM1
Alison, DL; Calvert, AH; Harrap, KR; Jackman, AL1
Lönn, S; Lönn, U1
Mackinnon, WB; Nott, SE; Piper, AA; Tattersall, MH1
Clarkson, BD; Doblin, JM; Fried, J; Perez, AG1
Houghton, JA; Houghton, PJ1
Domin, BA; Mahony, WB; Zimmerman, TP1
Fujimoto, S; Kihara, Y; Nagai, K; Nagasawa, K; Okuda, H1
Cabezas-Herrera, J; Campo, LS; Navarro-Perán, E; Rodríguez-López, JN1

Other Studies

11 other study(ies) available for fluorouracil and hypoxanthine

ArticleYear
Biochemical modulation of 5-fluorouracil with or without leucovorin by a low dose of brequinar in MGH-U1 cells.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Cell Survival; Cytidine Triphosphate; Deoxyuracil Nucleotides; Dose-Response Relationship, Drug; Drug Interactions; Fluorodeoxyuridylate; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; Leucovorin; Phosphoribosyl Pyrophosphate; Thymidylate Synthase; Tumor Cells, Cultured; Uridine Triphosphate

1992
AZT: a biochemical response modifier of methotrexate and 5-fluorouracil cytotoxicity in human ovarian and pancreatic carcinoma cells.
    Cancer communications, 1991, Volume: 3, Issue:4

    Topics: Animals; Binding, Competitive; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Female; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Methotrexate; Ovarian Neoplasms; Pancreatic Neoplasms; Rats; Thymidine; Thymidine Kinase; Tumor Cells, Cultured; Zidovudine

1991
Modulation of cytotoxicity and metabolism of 5-fluorouracil in two intestine cell lines.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: Cell Cycle; Cell Line; DNA; Drug Synergism; Floxuridine; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Organophosphorus Compounds; Pentosyltransferases; Pyrimidine Phosphorylases; Ribosemonophosphates; RNA; Thymidine; Thymidylate Synthase

1986
Increased thymidylate synthase in L1210 cells possessing acquired resistance to N10-propargyl-5,8-dideazafolic acid (CB3717): development, characterization, and cross-resistance studies.
    Cancer research, 1986, Volume: 46, Issue:6

    Topics: Animals; Antineoplastic Agents; Cells, Cultured; Deoxyuridine; Drug Resistance; Floxuridine; Fluorouracil; Folic Acid; Folic Acid Antagonists; Hypoxanthine; Hypoxanthines; Kinetics; Leukemia L1210; Mice; Quinazolines; Thymidylate Synthase; Tritium

1986
The increased cytotoxicity in colon adenocarcinoma of methotrexate-5-fluorouracil is not associated with increased induction of lesions in DNA by 5-fluorouracil.
    Biochemical pharmacology, 1986, Jan-15, Volume: 35, Issue:2

    Topics: Adenocarcinoma; Cell Division; Cell Survival; Cells, Cultured; Colonic Neoplasms; DNA, Neoplasm; Drug Administration Schedule; Drug Interactions; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; Methotrexate

1986
Critical modulation by thymidine and hypoxanthine of sequential methotrexate-5-fluorouracil synergism in murine L1210 cells.
    Cancer research, 1983, Volume: 43, Issue:11

    Topics: Animals; Cell Survival; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Hypoxanthine; Hypoxanthines; Kinetics; Leukemia L1210; Methotrexate; Mice; Thymidine

1983
Factors modifying the synergistic toxicity of deoxycytidine in combination with thymidine plus 5-fluorouracil in HeLa cells.
    Cell and tissue kinetics, 1983, Volume: 16, Issue:6

    Topics: Cell Survival; Culture Media; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Fluorouracil; HeLa Cells; Humans; Hypoxanthine; Hypoxanthines; Interphase; Kinetics; Mitosis; Thymidine

1983
Combinations of 5-FU, hypoxanthine and allopurinol in chemotherapy for human colon adenocarcinoma xenografts.
    Cancer treatment reports, 1982, Volume: 66, Issue:5

    Topics: Adenocarcinoma; Allopurinol; Animals; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Transplantation, Heterologous

1982
Transport of 5-fluorouracil and uracil into human erythrocytes.
    Biochemical pharmacology, 1993, Aug-03, Volume: 46, Issue:3

    Topics: Adenine; Biological Transport; Erythrocytes; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Nucleic Acids; Nucleosides; Papaverine; Tritium; Uracil

1993
Anticancer nucleobase analogues 6-mercaptopurine and 6-thioguanine are novel substrates for equilibrative nucleoside transporter 2.
    International journal of pharmaceutics, 2007, Mar-21, Volume: 333, Issue:1-2

    Topics: Animals; Antimetabolites, Antineoplastic; Binding, Competitive; Cell Membrane Permeability; Chlorocebus aethiops; COS Cells; Equilibrative-Nucleoside Transporter 2; Fluorouracil; Guanine; Hypoxanthine; Kinetics; Mercaptopurine; Mice; Thioguanine; Transfection; Uracil; Uridine

2007
Effects of folate cycle disruption by the green tea polyphenol epigallocatechin-3-gallate.
    The international journal of biochemistry & cell biology, 2007, Volume: 39, Issue:12

    Topics: Adenosine; Apoptosis; Caco-2 Cells; Camellia sinensis; Caspase 3; Catechin; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; DNA Replication; Fluorouracil; Folic Acid Antagonists; Gene Expression; Humans; Hypoxanthine; Leucovorin; Models, Biological; NF-kappa B; Protein Binding; Receptor, Adenosine A3; Tetrahydrofolate Dehydrogenase; Thymine; Transcription, Genetic

2007
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