fluorouracil has been researched along with hydroxyurea in 262 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 114 (43.51) | 18.7374 |
| 1990's | 73 (27.86) | 18.2507 |
| 2000's | 45 (17.18) | 29.6817 |
| 2010's | 27 (10.31) | 24.3611 |
| 2020's | 3 (1.15) | 2.80 |
| Authors | Studies |
|---|---|
| Hansch, C; Khwaja, TA; Selassie, CD | 1 |
| Bey, P; Farr, RA; Lippert, BJ; Sunkara, PS | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Adibpour, N; Babai, M; Doroudi, AR; Khalaj, A; Khoshayand, MR; Ostad, SN | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Bradley, TR; Hodgson, GS; Rosendaal, M | 1 |
| Calvert, AH; Hill, BT; Hughes, KB; Price, LA; Shaw, HJ | 1 |
| DeWys, WD | 1 |
| Borsos, T; Ohanian, SH; Segerling, M | 1 |
| Carter, SK; Goldsmith, MA | 1 |
| Davies, J; Schindler, D | 1 |
| Kaidbey, KH | 1 |
| Perlin, E | 1 |
| Carter, SK; Wasserman, TH | 1 |
| Murphy, GP | 1 |
| Crumley, J; Wilkinson, DS | 1 |
| Raghavan, V | 1 |
| Bienkowski, M; Dunn, JR; Honn, KV; Marnett, LJ; Morgan, LR | 1 |
| Brodsky, I; Conroy, JF; Krein, BM | 1 |
| Kleckow, M; Mattern, J; Vogt-Moykopf, I; Volm, M; Wayss, K | 1 |
| Adwankar, MK; Alate, AD; Amonkar, AJ; Khandalekar, DD; Sahasrabudhe, MB | 1 |
| Block, NL; Camuzzi, F; Claflin, A; Politano, VA; Stover, B; Troner, M | 1 |
| Marsh, JC | 1 |
| Rees, RB | 1 |
| Hoffbrand, AV; Hooton, JW | 2 |
| Feola, J; Maruyama, Y | 1 |
| Baker, H | 1 |
| Kaufmann, M; Mattern, J; Volm, M; Wayss, K | 1 |
| Lokich, JJ; Pitman, SW; Skarin, AT | 1 |
| Levin, VA; Prados, MD | 1 |
| Haraf, DJ; McEvilly, JM; Mick, R; Panje, WR; Vokes, EE; Weichselbaum, RR | 1 |
| Gebbia, N; Gebbia, V; Ingria, F; Rausa, L; Russo, A; Spadafora, G; Testa, A; Valenza, R; Zerillo, G | 1 |
| Beckett, M; Karrison, T; Vokes, EE; Weichselbaum, RR | 1 |
| Schilsky, RL | 1 |
| Kinsella, TJ; McGinn, CJ | 1 |
| Stehman, FB | 1 |
| Dawson, DA; Wilke, TS | 1 |
| Kim, RY; Meredith, RF; Peters, GE; Salter, MM; Spencer, SA; Weppelmann, B; Wheeler, RH | 1 |
| Haraf, DJ; Panje, WR; Vokes, EE; Weichselbaum, RR | 2 |
| Haraf, DJ; Panje, WR; Schilsky, RL; Vokes, EE; Weichselbaum, RR | 1 |
| Moran, RG; Muggia, FM | 1 |
| Daniilidis, J; Destouni-Salem, E; Fountzilas, G; Kalogera-Fountzila, A; Sombolos, K; Sridhar, KS; Tourkantonis, A; Vritsios, A; Zaramboukas, T | 1 |
| Egorin, MJ; Haraf, DJ; Mick, R; Moormeier, JA; Ratain, MJ; Vokes, EE; Weichselbaum, RR | 1 |
| Golomb, HM; Hoffman, PC; Janisch, L; Ratain, MJ; Schilsky, RL; Vokes, EE | 1 |
| Anderson, N; Bern, M; Coco, F; Gonsalves, L; Lokich, J; Moore, C; Zipoli, T | 1 |
| Algeri, R; Bacchi, M; Bartolucci, R; Cornia, E; Di Costanzo, F; Figoli, F; Malacarne, P; Marzola, M; Passalacqua, R; Zironi, S | 1 |
| Cheung, NK; Exelby, PR; Gulati, SC; Kushner, BH; Kwon, JH; O'Reilly, RJ | 1 |
| Bhalla, K; Bhalla, M; Birkhofer, M; Cole, J; Hindenburg, A; Ince, C; Lutzky, J | 1 |
| Antoniw, P; Bagshawe, KD; Boden, JA; Boxer, GM; Patridge, TA; Pedley, RB; Sharma, K; Southall, PJ | 1 |
| Bitran, JD; Ferguson, MK; Golomb, HM; Hoffman, PC; Jacobs, R; Krishnasamy, S; Vijayakumar, S; Vokes, EE | 1 |
| Ardiet, JM; Clavel, M; Gignoux, B | 1 |
| Apostolidis, T; Daniilidis, J; Fountzilas, G; Kalogera-Fountzila, A; Tourkantonis, A; Vritsios, A | 1 |
| Anastasakis, C; Daniilidis, J; Delis, V; Fountzilas, G; Haritanti, A; Nicolaou, A; Sideras, T; Sridhar, K; Vritsios, A | 1 |
| Clifford, P; Grant, HR | 1 |
| Awan, AM; Goldman, MD; Mick, R; Moran, WJ; Panje, WR; Schilsky, RL; Tybor, AG; Vokes, EE; Weichselbaum, RR | 1 |
| Portnoĭ, AS | 1 |
| Douglass, HO; Engstrom, PF; MacIntyre, JM; Schutt, AJ | 1 |
| Keyomarsi, K; Moran, RG | 1 |
| Levin, VA | 1 |
| Berger, M; Chamberlain, M; Choucair, A; Da Silva, V; Davis, RL; Levin, VA; Liu, HC; Murovic, J; Phuphanich, S; Seager, M | 1 |
| Axelson, JA; Clark, RH; Dimitrov, NV | 1 |
| Shapiro, JR; Shapiro, WR | 1 |
| Awan, AM; Guarnieri, CM; Moran, WJ; Panje, WR; Schilsky, RL; Vokes, EE; Weichselbaum, RR | 1 |
| Helson, L; Kushner, BH | 1 |
| Diasio, RB; Schuetz, JD; Wallace, HJ | 1 |
| Edwards, MS; Fulton, D; Levin, V; Prados, M; Rodriguez, LA; Silver, P | 1 |
| Fitzgerald, GB; Wick, MM | 1 |
| Bagshawe, KD; Boden, J; Boxer, GM; Britton, DW; Green, A; Partridge, T; Pedley, B; Sharma, S; Southall, P | 1 |
| Bantle, JA; Dawson, DA | 1 |
| Cognetti, F; Dalesio, O; Dodion, P; Kirkpatrick, A; Rozencweig, M; van Rymenant, M | 1 |
| Boerrigter, GH; Braakhuis, BJ; Heinerman, EC; Snow, GB | 1 |
| Ashman, CR; Davidson, RL; Kaufman, ER | 1 |
| Moore, JV | 1 |
| Hoshino, T; Nagashima, T | 1 |
| Pavone-Macaluso, M | 1 |
| Broder, LE; Rall, DP | 1 |
| Greenwald, ES | 1 |
| Bajetta, E; Bonadonna, G; Tancini, G | 1 |
| Simmonds, WP | 1 |
| Almeyda, J; Levantine, A | 1 |
| Israel, L | 1 |
| Bagshaw, MA; Goffinet, DR | 1 |
| Sugiura, K | 1 |
| Watne, AL | 1 |
| Falkson, G; Geddes, EW | 1 |
| Adamson, DJ; Bowdon, BJ; Vail, MH; Wheeler, GP | 1 |
| Frankfurt, OS | 1 |
| Falkson, G; Falkson, HC; Sandison, AG; van der Merwe, AM; van Dyk, JJ | 1 |
| Korfsmeier, KH | 1 |
| Clarkson, SG | 1 |
| Moertel, CG | 1 |
| Hellmann, K; Murkin, GE | 1 |
| Krishnan, D; Painter, RB | 1 |
| Carter, SK | 1 |
| Covey, TH; Watne, AL | 1 |
| Jusko, WJ | 1 |
| Barrett, JL; Sayers, P | 1 |
| Lee, TC; Maruyama, Y; Sullivan, S | 1 |
| deKernion, JB; Persky, L; Rose, D; Soloway, MS | 1 |
| Birkett, S; Salaman, DF | 1 |
| Lüscher, EF | 1 |
| Benckhuijsen, C | 1 |
| von Kreybig, T | 1 |
| Stutzman, L | 1 |
| Burns, BC; Rutledge, F; Smith, JP; Soffar, S | 1 |
| Rassow, J; Scherer, E | 1 |
| Bonder, RH; Van Scott, EJ | 2 |
| Groth, DP; Horwitz, S; Vogler, WR | 1 |
| Brockman, RW; Lloyd, HH; Mellett, LB; Montgomery, JA; Schabel, FM; Skipper, HE; Wilkoff, LJ | 1 |
| McGuire, WL; O'Malley, BW | 1 |
| Kaufman, JJ | 1 |
| Hills, WJ; Rufino, C; Stehlin, JS | 1 |
| Allen, J; Edwards, MS; Levin, VA; Ortega, J; Vestnys, P; Wara, WM | 1 |
| Kallio, T; Kukko, E | 1 |
| Anger, G; Fink, R; Höche, D | 1 |
| Glick, JH; Taylor, SG; Zehngebot, LM | 1 |
| Barzan, L; Comoretto, R; Galligioni, E; Grigoletto, E; Magri, MD; Tirelli, U; Trovò, MG; Tumolo, S; Veronesi, A | 1 |
| Jacobs, C; Mead, GM | 1 |
| Engstrom, PF; Klaassen, DJ; MacIntyre, JM; Mittelman, A | 1 |
| De Vecchis, L; Lagomarsino Caprino, MC; Mazzei, T; Periti, P; Popoli, P | 1 |
| deKernion, JB; Gibbons, R; Johnson, DE; Loening, S; Murphy, GP; Pontes, JE; Prout, GR; Schmidt, JD; Scott, WW; Slack, NH; Soloway, M | 1 |
| Scott, JM; Weir, DG | 1 |
| Blum, RH; Dubin, N; Kao, AK; Lerner, WA; Muggia, FM; Speyer, JL; Stark, R; Wernz, JC | 1 |
| Bellamy, AS; Hill, BT | 1 |
| Hoshino, T; Kobayashi, S | 1 |
| Ballatori, E; Biscottini, B; Buzzi, F; Di Costanzo, F; Falchi, R; Fatati, G; Grignani, F; Liberati, AM | 1 |
| Holmes, W; Keller, G; Phillips, RA | 1 |
| Lerner, H; Marcovitz, E; Zaren, H | 1 |
| Chłopkiewicz, B; Koziorowska, JH | 1 |
| Seller, MJ | 1 |
| Douglass, HO; Engstrom, PF; MacIntyre, JM; Mittelman, A; Muggia, F | 1 |
| Levin, VA; Vestnys, PS; Wilson, CB | 1 |
| Danno, K; Horio, T | 1 |
| Schmidt, JD | 1 |
| Ross, DW | 1 |
| Baines, P; Bol, S; Rosendaal, M | 1 |
| Gans, JH; Smuckler, EA | 1 |
| Haraf, DJ; Levin, J; Malone, D; Stenson, K; Stupp, R; Vokes, EE; Weichselbaum, RR | 1 |
| Vokes, EE | 1 |
| Haraf, DJ; McEvilly, JM; Mick, R; Vokes, EE; Weichselbaum, RR | 1 |
| Drinkard, LC; Ferguson, MK; Golomb, HM; Haraf, DJ; Hoffman, PC; Lane, NJ; Vogelzang, NJ; Vokes, EE; Watson, S | 1 |
| Haraf, D; Malone, D; Moran, W; Stupp, R; Sweeney, P; Vokes, EE; Weichselbaum, RR; Wenig, B | 1 |
| Crittenden, RB; Peters, SO; Quesenberry, PJ; Ramshaw, HS; Rao, SS; Weier, HU | 1 |
| Haraf, DJ; Kies, M; Kozloff, M; Mick, R; Mittal, B; Moran, WJ; Panje, W; Pelzer, H; Vokes, EE; Wenig, B | 1 |
| Drinkard, LC; Ferguson, MK; Haraf, DJ; Hoffman, PC; Reeder, LB; Vokes, EE | 1 |
| Buccellato, C; Cipolla, C; Comande, S; Curto, G; Gebbia, N; Gebbia, V; Latteri, M; Testa, A; Valenza, R | 1 |
| Bitran, JD; Ferguson, MK; Golomb, HM; Haraf, DJ; Hoffman, PC; Vokes, EE | 1 |
| Haraf, DJ; Mick, R; Vokes, EE; Weichselbaum, RR; Wong, WW | 1 |
| Rose, PG | 2 |
| Armand, JP; Cioloca, C; Constans, JP; Cvitkovic, FB; Haie-Meder, C; Maugis, N; Papadimitrakopoulou, V | 1 |
| Berezin, F; Brachman, D; Charette, J; Dolan, ME; Krishnasamy, S; Mick, R; Ratain, MJ; Schilsky, RL; Vokes, EE; Whitman, G | 1 |
| Ahlgren, JD; Anderson, N; Kemeny, N; Lokich, JJ | 1 |
| Etienne, MC; Fischel, JL; Formento, P; Haaz, MC; Milano, G; Renée, N | 1 |
| Avvento, L; Burns, P; Chowhan, N; Fiore, J; Hagag, N; Hentschel, P; Lipera, W; Madajewicz, S; Matei, D; Zarrabi, H | 1 |
| Bartolucci, R; Di Costanzo, F; el-Taani, H; Madejewicz, S; Manzione, L; Parriani, D; Tagliaventi, M; Valenti, L | 1 |
| Beerblock, K; Bennamoun, M; de Gramont, A; Demuynck, B; Grangé, JD; Krulik, M; Louvet, C; Mal, F; Moreau, S; Soubrane, D; Varette, C; Zylberait, D | 1 |
| Haynes, H; Rozenblit, A; Schechner, R; Wadler, S; Wiernik, PH | 1 |
| Colucci, G; Fortunato, S; Gebbia, N; Gebbia, V; Giotta, F; Giuseppe, S; Majello, E; Pezzella, G; Riccardi, F; Testa, A | 1 |
| Horowitz, R; Wadler, S | 1 |
| Haraf, DJ; Vokes, EE; Weichselbaum, RR | 1 |
| Haraf, DJ; List, M; Stenson, K; Vokes, EE; Weichselbaum, RR; Witt, ME | 1 |
| Andolenko, P; Bardet, E; Colin, P; Douillard, JY; Dubray, B; Extra, JM; Ganem, G; Goudier, MJ; Hennequin, C; Maron, D; Martin, P; Michel-Langlet, P; Morvan, F; Raoul, Y; Walter, S | 1 |
| Dakhil, S; Hess, K; Jaeckle, KA; Kaba, SE; Kyritsis, AP; Levin, VA; Mercier, R; Yung, WK | 1 |
| Grillot, DA; Nuñez, G; Simonian, PL | 1 |
| Bundy, BN; Deppe, G; Kucera, PR; O'Connor, DM; Reddy, S; Stehman, FB | 1 |
| Beerblock, K; Carola, E; de Gramont, A; Demuynck, B; Krulik, M; Louvet, C; Raymond, E; Tournigand, C | 1 |
| Tsukuda, M | 1 |
| Brockstein, B; Fasanmade, A; Glisson, B; Haraf, DJ; Klepsch, A; Lippman, SM; Ratain, MJ; Stenson, K; Stupp, R; Sulzen, L; Vokes, EE; Weichselbaum, RR | 1 |
| Athanasiadis, I; Haraf, DJ; Kies, MS; Kozloff, M; Mittal, B; Pelzer, H; Rademaker, AW; Vokes, EE; Weichselbaum, RR; Wenig, B | 1 |
| Algeri, R; Angiona, S; Belsanti, V; Boni, C; Corgna, E; Di Costanzo, F; Figoli, F; Gasperoni, S; Luppi, G; Malacarne, P; Marzola, M; Passalacqua, R; Sdrobolini, A; Zironi, S | 1 |
| Haynes, H; Makower, D; Schwartz, EL; Wadler, S | 1 |
| Lindner, H | 1 |
| Brockstein, BE; Haraf, DJ; Humerickhouse, R; Vokes, EE | 1 |
| Fleming, G; Mundt, AJ; Quiet, C; Rotmensch, J; Waggoner, S | 1 |
| Beenken, SW; Conner, W; Meredith, RF; Peters, GE; Salter, MM; Smith, J; Spencer, SA; Wheeler, RH | 1 |
| Horowitz, R; Schwartz, EL; Wadler, S; Zhang, HY | 1 |
| Haraf, DJ; Kies, M; Mittal, B; Pelzer, H; Rademaker, AW; Stenson, K; Sulzen, L; Vokes, EE; Weichselbaum, RR; Wenig, B; Witt, ME | 1 |
| Bundy, BN; Clarke-Pearson, DL; Deppe, G; Insalaco, S; Maiman, MA; Rose, PG; Thigpen, JT; Watkins, EB | 1 |
| Brockstein, BE; Haraf, DJ; Vokes, EE; Weichselbaum, RR | 1 |
| Monaghan, J | 1 |
| Fan, W; Johnson, KR; Young, KK | 1 |
| Bates, NP; Braybrooke, JP; Ganesan, TS; Harris, AL; Madigan, D; O'Byrne, KJ; Philip, PA; Propper, DJ; Saunders, MP; Talbot, DC; Taylor, MA | 1 |
| Berkenblit, R; Damle, S; Haynes, H; Kaleya, R; Ladner, RD; Murgo, A; Schechner, R; Wadler, S | 1 |
| Chauvergne, J; Fervers, B; Fondrinier, E; Guastalla, JP; Haie-Meder, C; Lhommé, C; Resbeut, M | 1 |
| Hsu, CP; Yang, CC; Yang, SD | 1 |
| Dolan, ME; Haraf, DJ; Hsieh, YC; Humerickhouse, R; Kies, MS; List, M; Mittal, BB; Pelzer, H; Stenson, K; Sulzen, L; Vokes, EE; Weichselbaum, RR; Witt, ME | 1 |
| Micke, O; Schaefer, U; Schueller, P; Willich, N | 1 |
| Brockstein, B; Haraf, DJ; Stenson, K; Sulzen, L; Vokes, EE; Weichselbaum, RW; Witt, ME | 1 |
| Eifel, PJ | 1 |
| de Crevoisier, R; Haie-Meder, C; Lhommé, C; Morice, P; Resbeut, M | 1 |
| Brockstein, B; Chung, T; Haraf, DJ; Kies, MS; List, M; Mittal, BB; Pelzer, H; Portugal, L; Rademaker, A; Rosen, F; Stenson, K; Vokes, EE; Weichselbaum, R | 1 |
| Smart, T | 1 |
| Bobin, S; Bourhis, J; De Crevoisier, R; Domenge, C; Eschwege, F; Janot, F; Koscielny, S; Luboinski, B; Lusinchi, A; Wibault, P | 1 |
| Benoit, B; Carlson, J; D'Hondt, L; Dooner, MS; Grimaldi, C; Lambert, JF; Quesenberry, PJ; Reilly, J; Wuu, J | 1 |
| Harris, J; Machtay, M; Meredith, R; Rotman, M; Schultz, C; Spanos, W; Spencer, SA; Wheeler, RH | 1 |
| Chen, H; Pierce, A; Whetton, T | 1 |
| Kelly, S; Nguyen, M; Sun, D; Urrabaz, R; Weitman, S | 1 |
| Beenken, S; Meredith, R; Nabel, L; Peters, G; Salter, M; Soong, SJ; Spencer, S; Wheeler, R; Wooten, A | 1 |
| Brockstein, BE; Fung, BB; Haraf, DJ; Kies, MS; List, MA; Mittal, BB; Pelzer, H; Portugal, L; Rademaker, AW; Rosen, FR; Stenson, K; Vokes, EE; Weichselbaum, RR; Witt, ME | 1 |
| André, T; Beerblock, K; Cady, J; Carrat, F; de Gramont, A; Gamelin, E; Louvet, C; Mabro, M; Mal, F; Vaillant, JC | 1 |
| Haraf, DJ; Kies, MS; Mittal, BB; Oh, JL; Vokes, EE; Weichselbaum, RR; Witt, ME | 1 |
| Brockstein, BE; Haraf, DJ; Kies, MS; List, MA; Mittal, BB; Pelzer, H; Portugal, L; Rademaker, AW; Rosen, FR; Stenson, K; Vokes, EE; Weichselbaum, RR; Witt, ME | 1 |
| André, T; Artru, P; Carola, E; de Gramont, A; Gilles-Amar, V; Krulik, M; Louvet, C; Mabro, M | 1 |
| Argiris, A; Haraf, DJ; Kies, MS; Vokes, EE | 1 |
| Argiris, A; Brockstein, BE; Haraf, DJ; List, MA; Mittal, BB; Pelzer, H; Portugal, L; Rosen, FR; Stenson, K; Vokes, EE; Weichselbaum, RR; Witt, ME | 1 |
| Haynes, H; Kaleya, R; Kaubisch, A; Rozenblit, A; Wadler, S | 1 |
| Cengiz, M; Ozyar, E | 1 |
| Ahn, JM; Kim, JH; Lee, HC; Lee, SN | 1 |
| Kohonen, M; Salmo, M; Tolonen, P; Victorzon, M | 1 |
| Cooper, JS; Demas, W; Forastiere, AA; Garden, AS; Glisson, BS; Gore, E; Harris, J; Horwitz, EM; Jones, C; Nabell, L; Ridge, JA; Vokes, EE | 1 |
| Brockstein, B; Fung, BB; Haraf, DJ; Kies, MS; Mittal, BB; Pelzer, H; Portugal, L; Rademaker, AW; Rosen, F; Stenson, KM; Vokes, EE; Weichselbaum, RW; Wenig, B; Witt, ME | 1 |
| Huang, XW; Lawrence, TS; Tang, ZY; Zhang, M | 1 |
| Armand, JP; Domenge, C; Faivre, S; Gatineau, M; Janot, F; Julieron, M; Luboinski, B; Marti, A; Raymond, E; Rixe, O; Temam, S | 1 |
| Chmura, SJ; Haraf, DJ; Kao, J; Milano, MT; Salama, JK; Stenson, KM; Vokes, EE; Witt, ME | 1 |
| Chua, ET; Goh, BC; Hsieh, WS; Lim, HL; Loh, KS; Lu, JJ; Shakespeare, TP; Soo, RA; Tan, KS; Wong, AS | 1 |
| Brockstein, B; Cohen, EE; Haraf, DJ; Kies, MS; Kocherginsky, M; List, MA; Mittal, BB; Rosen, F; Stenson, KM; Vokes, EE; Williams, R; Witt, ME | 1 |
| Ang, KK; Harris, J; Machtay, M; Meredith, R; Rotman, M; Schultz, C; Spanos, W; Spencer, SA; Wheeler, RH | 1 |
| Blair, EA; Cohen, EE; Dekker, A; Haraf, DJ; Mauer, A; Seiwert, TY; Stenson, K; Vokes, EE | 1 |
| Chen, HX; Cohen, EE; Dekker, A; Haraf, DJ; Kocherginsky, M; Seiwert, TY; Stenson, K; Vokes, EE; Weichselbaum, RR; Witt, ME | 1 |
| Cohen, EE; Haraf, DJ; Knab, BR; Salama, JK; Solanki, A; Stenson, KM; Vokes, EE; Witt, ME | 1 |
| Argiris, A; Brockstein, BE; Cohen, EE; Haraf, DJ; Kistner, EO; Mittal, BB; Rosen, F; Salama, JK; Stenson, KM; Vokes, EE; Witt, ME | 1 |
| Bardet, E; Benhamou, E; Bensadoun, RJ; Bourhis, J; Castaing, M; de Raucourt, D; Dolivet, G; Ferron, C; Géry, B; Grégoire, V; Hamoir, M; Janot, F; Julieron, M | 1 |
| Manfredi, JJ; Varmeh, S | 1 |
| Moore, DH | 1 |
| Blair, EA; Haraf, DJ; Pederson, AW; Salama, JK; Stenson, KM; Vokes, EE; Witt, ME | 2 |
| Emond, MJ; Lauper, JM; Mao, FJ; Monnat, RJ; Sidorova, JM | 1 |
| Burri, RJ; Genden, EM; Gupta, V; Gurudutt, V; Kao, J; Packer, SH; Policarpio, EL; Rivera, M; Som, PM; Teng, M | 1 |
| Blair, EA; Cohen, EE; Haraf, DJ; Kunnavakkam, R; Salama, JK; Seiwert, T; Stenson, KM; Vokes, EE; Williams, R; Witt, ME | 1 |
| Ali, S; Lanciano, R; Rose, PG; Stehman, FB; Whitney, CW | 1 |
| Blair, EA; Choe, KS; Cohen, EE; Haraf, DJ; Portugal, L; Salama, JK; Seiwert, TY; Solanki, A; Stenson, KM; Villaflor, VM; Vokes, EE; Witt, ME | 1 |
| Blair, EA; Cohen, EE; Haraf, DJ; Pederson, AW; Portugal, L; Salama, JK; Seiwert, T; Stenson, KM; Villaflor, VM; Vokes, EE; Witt, ME | 1 |
| Aguirre-Ghiso, J; Cannan, D; Forsythe, K; Genden, EM; Gupta, V; Gurudutt, V; Kao, J; Ko, EC; Lau, KH; Misiukiewicz, K; Packer, SH; Rivera, M; Sikora, AG; Teng, MS; Tong, CC | 1 |
| Brandl, CJ; Davey, MJ; Sandre, MK; Stead, BE | 1 |
| Blair, EA; Cohen, EEW; Haraf, DJ; List, M; Mouw, KW; Salama, JK; Solanki, AA; Stenson, KM; Vokes, EE; Witt, ME | 1 |
| Mathews, CK | 1 |
| Blair, E; Cohen, EE; Golden, DW; Haraf, DJ; Nwizu, T; Rudra, S; Stenson, KM; Vokes, EE; Witt, ME | 1 |
| Blair, EA; Cohen, EE; Darga, T; Haraf, D; Lingen, MW; Salama, JK; Seiwert, TY; Stenson, K; Villaflor, V; Vokes, EE; Weichselbaum, RR; Witt, ME | 1 |
| Adachi, N; Fujita, M; Harada, H; Hiraoka, M; Hirota, K; Kurosawa, A; Omura, M; Sasanuma, H; Takeda, S; Yamamoto, KN | 1 |
| Agulnik, MB; Braegas, B; Brockstein, BE; Cohen, EE; Egan, R; Haraf, DJ; Huang, CH; Karrison, TG; Kocherginsky, M; Kumar, P; Marchand, P; Mehra, R; Mittal, BB; Mueller, J; Ondrey, F; Raez, LE; Samant, S; Seiwert, TY; Villaflor, VM; Vokes, EE; Yunus, F | 1 |
| Java, JJ; Lanciano, R; Rose, PG; Stehman, FB; Thomas, GM; Whitney, CW | 1 |
| Ahn, C; Choi, Y; Hong, EJ; Jeung, EB; Kang, HY; Yang, H | 1 |
| Bacchus, ID; Mittal, BB; Refaat, T; Sachdev, S; Sathiaseelan, V | 1 |
| Chang, CL; Chen, JH; Chen, TM; Lai, MT; Lee, FP; Lin, KC; Wu, CC; Wu, SY; Yen, YC; Yuan, KS | 1 |
| Ahn, C; Hong, EJ; Jeung, EB; Kang, HS; Kang, HY | 1 |
| Borges, RDS; Brasil, DDSB; Campos, JM; Costa, JDS; Costa, KDSL; Ferreira, EFB; Macêdo, WJDC; Ramos, RDS; Santos, CBRD; Silva, CHTPD | 1 |
| Fukada, M; Futamura, M; Imai, H; Imai, T; Iwata, Y; Matsuhashi, N; Mori, R; Okumura, N; Sato, Y; Suetsugu, T; Takahashi, T; Tanaka, H; Tanaka, Y; Yasufuku, I; Yoshida, K | 1 |
| Guan, Z; Li, S; Liang, Y; Niu, B; Wang, J; Wang, X; Yang, A; Yu, J; Zhu, Z | 1 |
41 review(s) available for fluorouracil and hydroxyurea
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Current concepts of chemotherapy combined with other modalities for head and neck cancer.
Topics: Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Immunotherapy; Laryngeal Neoplasms; Leucovorin; Methotrexate; Neoplasm Metastasis; Neoplasms; Radiotherapy; Vinblastine | 1975 |
The integration of chemotherapy into a combined modality approached to cancer therapy. V. Squamous cell cancer of the head and neck.
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Laryngeal Neoplasms; Leucovorin; Lip Neoplasms; Lymphatic Metastasis; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Tongue Neoplasms | 1975 |
Inhibitors of macromolecular synthesis in yeast.
Topics: Acriflavine; Amphotericin B; Anisomycin; Anti-Bacterial Agents; Antineoplastic Agents; Cycloheximide; Dactinomycin; Daunorubicin; Deoxyadenosines; Depression, Chemical; DNA; Ethidium; Fluorouracil; Fungal Proteins; Hydroxyurea; Mitomycins; Nalidixic Acid; Phenazines; Phenylethyl Alcohol; Porfiromycin; Puromycin; RNA; Saccharomyces cerevisiae; Streptonigrin; Sulfanilamides; Triaziquone; Trichothecenes; Uracil | 1975 |
The effects of cancer chemotherapeutic agents on normal hematopoietic precursor cells: a review.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Asparaginase; Benzamides; Busulfan; Carmustine; Cisplatin; Cyclophosphamide; Cytarabine; Drug Evaluation, Preclinical; Erythrocytes; Fluorouracil; Hematopoietic Stem Cells; Humans; Hydroxyurea; Lomustine; Methotrexate; Nitrogen Mustard Compounds; Spleen; Vinca Alkaloids | 1976 |
Psoriasis: a review. II.
Topics: Adrenal Cortex Hormones; Anthralin; Azathioprine; Azauridine; Fluorouracil; Humans; Hydroxyurea; Lomustine; Mechlorethamine; Methotrexate; Psoriasis; Tars; Tretinoin; Ultraviolet Therapy | 1975 |
Biochemical pharmacology of chemotherapeutic drugs used as radiation enhancers.
Topics: Animals; Cisplatin; Fluorouracil; Humans; Hydroxyurea; Radiation-Sensitizing Agents | 1992 |
The experimental and clinical rationale for the use of S-phase-specific radiosensitizers to overcome tumor cell repopulation.
Topics: Animals; Cell Division; Fluorouracil; Humans; Hydroxyurea; Neoplasm Recurrence, Local; Neoplasms; Radiation-Sensitizing Agents; S Phase | 1992 |
Concurrent chemoradiation in carcinoma of the uterine cervix.
Topics: Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Hydroxyurea; Uterine Cervical Neoplasms | 1992 |
Treatment of colon cancer based on biochemical modulation of fluoropyrimidines by hydroxyurea.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Humans; Hydroxyurea | 1992 |
Combination of chemotherapy with radiotherapy: review of previous studies and new perspectives.
Topics: Antineoplastic Agents; Bleomycin; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Radiation-Sensitizing Agents | 1985 |
[Chemotherapy of prostatic cancer].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dacarbazine; Diethylstilbestrol; Doxorubicin; Estramustine; Fluorouracil; Humans; Hydroxyurea; Male; Melphalan; Methotrexate; Mitomycin; Mitomycins; Prednisolone; Procarbazine; Prostatic Neoplasms; Streptozocin; Vincristine | 1985 |
Chemotherapy of primary brain tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Eflornithine; Ependymoma; Fluorouracil; Glioblastoma; Humans; Hydroxyurea; Lomustine; Medulloblastoma; Methotrexate; Mitoguazone; Mitolactol; Neoplasm Recurrence, Local; Ornithine; Prednisone; Risk; Thioguanine; Vincristine | 1985 |
Principles of brain tumor chemotherapy.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Carbon Radioisotopes; Carmustine; Cell Line; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance; Fluorouracil; Glioma; Humans; Hydroxyurea; Infusions, Intra-Arterial; Karyotyping; Kinetics; Mannitol; Methotrexate; Podophyllotoxin; Procarbazine; Rats; Tumor Stem Cell Assay | 1986 |
Bromodeoxyuridine mutagenesis and deoxyribonucleotide pool imbalance in mammalian cells.
Topics: Animals; Base Composition; Bromodeoxyuridine; Cell Line; Cricetinae; Cytarabine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleotides; DNA; Drug Resistance; Fluorouracil; Hydroxyurea; Melanoma; Mutation; Ribonucleotide Reductases; Sister Chromatid Exchange; Thymidine | 1985 |
Chemotherapy of brain tumors.
Topics: Adult; Antineoplastic Agents; Azaguanine; Bleomycin; Brain Neoplasms; Child; Cyclophosphamide; Drug Synergism; Fluorouracil; Glioblastoma; Glioma; Humans; Hydroxyurea; Medulloblastoma; Methotrexate; Nitrogen Mustard Compounds; Nitrosourea Compounds; Plicamycin; Procarbazine; Streptonigrin; Vinblastine; Vincristine | 1972 |
Cancer chemotherapy. II.
Topics: Animals; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Cytarabine; Dactinomycin; Daunorubicin; Dimethylamines; Doxorubicin; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Imidazoles; Mercaptopurine; Mitomycins; Mitotane; Neoplasms; Nitrosourea Compounds; Pipobroman; Procarbazine; Streptonigrin; Streptozocin; Thioguanine; Triazenes; Triazines; Vinblastine; Vincristine | 1972 |
Drug reactions. XXIV. Cutaneous reactions to cytostatic agents.
Topics: Alopecia; Aminopterin; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Eruptions; Erythema; Fluorouracil; Gynecomastia; Humans; Hydroxyurea; Methotrexate; Photosensitivity Disorders; Pigmentation Disorders; Radiation Injuries; Stomatitis; Vinblastine | 1974 |
Clinical use of radiation sensitizing agents.
Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Bromodeoxycytidine; Bromodeoxyuridine; Bromouracil; Carcinoma, Squamous Cell; Dactinomycin; Dose-Response Relationship, Radiation; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Idoxuridine; Neoplasms; Neoplasms, Experimental; Radiation-Sensitizing Agents | 1974 |
Solid tumor chemotherapy: What have we to offer.
Topics: Adult; Antineoplastic Agents; Child; Cyclophosphamide; Dactinomycin; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Palliative Care; Thiotepa; Time Factors; Vincristine | 1970 |
Single and combination nonhormonal chemotherapy in breast cancer.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Drug Synergism; Female; Fluorouracil; Humans; Hydroxyurea; Melphalan; Menopause; Methotrexate; Mice; Vinblastine; Vincristine | 1972 |
[Biochemical aspects of the therapy of advanced malignant tumors].
Topics: Adrenal Cortex Hormones; Alkaloids; Androgens; Anti-Bacterial Agents; Cyclophosphamide; DNA; DNA, Neoplasm; Estrogens; Fluorouracil; Folic Acid Antagonists; Humans; Hydroxyurea; Mercaptopurine; Neoplasms; Nucleic Acids; Protein Biosynthesis; Ribosomes; RNA, Messenger; RNA, Neoplasm; Vinblastine | 1966 |
Chemotherapy and the life cycle of leukaemic cells. A comparison between the growth characteristics of human acute leukaemia and the murine leukaemia L 1210.
Topics: Anilides; Animals; Cell Division; Cyclophosphamide; Cytarabine; DNA, Neoplasm; Fluorouracil; Humans; Hydroxyurea; In Vitro Techniques; Leukemia; Leukemia L1210; Leukemia, Lymphoid; Mechlorethamine; Mercaptopurine; Methotrexate; Mice; Mitosis; Nitroso Compounds; Prednisone; Thymidine; Time Factors; Tritium; Vinblastine; Vincristine | 1969 |
[Carcinogenesis and teratogenesis. Comparative studies from the viewpoint of teratology].
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Animals; Antineoplastic Agents; Carcinogens; Cyclophosphamide; Embryo, Mammalian; Female; Fetus; Fluorouracil; Gestational Age; Hydroxamic Acids; Hydroxyurea; Mannomustine; Mechlorethamine; Mercaptopurine; Nitroso Compounds; Pregnancy; Rats; Urethane | 1970 |
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Mechlorethamine; Mercaptopurine; Methotrexate; Procarbazine; Vinblastine | 1980 |
Changing role of chemotherapy in treatment of head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Recurrence | 1982 |
Drug-induced megaloblastic change.
Topics: Cyclophosphamide; Cytarabine; DNA; Erythrocytes, Abnormal; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Hydroxyurea; Megaloblasts; Methotrexate; Phenytoin; Pyrimethamine; Ribonucleotides; Thymidine Monophosphate; Thymidylate Synthase; Triamterene; Trimethoprim | 1980 |
The role of paclitaxel in the treatment of head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Radiotherapy, Adjuvant; Tumor Cells, Cultured | 1995 |
Fluorouracil modulation in head and neck cancer.
Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Immunologic Factors; Interferons; Leucovorin; Methotrexate | 1993 |
Hydroxyurea with continuous infusion paclitaxel, 5-fluorouracil, and concomitant radiotherapy for poor-prognosis head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Intravenous; Paclitaxel | 1995 |
Concomitant chemoradiotherapy for non-small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chicago; Cisplatin; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Fluorouracil; Humans; Hydroxyurea; Immunologic Factors; Interferon-alpha; Leucovorin; Lung Neoplasms; Pilot Projects; Randomized Controlled Trials as Topic; Treatment Outcome | 1994 |
Locally advanced cervical carcinoma: the role of chemoradiation.
Topics: Carcinoma; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Hydroxyurea; Uterine Cervical Neoplasms | 1994 |
Recent advances in the treatment of advanced colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colorectal Neoplasms; Drug Administration Schedule; Drug Interactions; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Hydroxyurea; Infusions, Intra-Arterial; Leucovorin; Methotrexate; Neoplasm Staging; Phosphonoacetic Acid; Prospective Studies; Randomized Controlled Trials as Topic | 1993 |
Modulation of 5-FU/alpha-interferon with high-dose continuous infusion hydroxyurea.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Fluorouracil; Humans; Hydroxyurea; Interferon-alpha; Ribonucleotide Reductases | 1995 |
[Chemoradiotherapy for patients with advanced head and neck cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Radiation-Sensitizing Agents; Radiotherapy Dosage | 1997 |
Oral 5-FU alternatives for the treatment of head and neck cancer.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Etoposide; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Neoplasm Recurrence, Local; Tegafur; Uracil | 1998 |
[Standards, options and recommendations: concomitant radiochemotherapy for cancer of the cervix: a critical analysis of the literature and update of SOR].
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Epirubicin; Female; Fluorouracil; Humans; Hydroxyurea; Lymphatic Metastasis; Multicenter Studies as Topic; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Practice Guidelines as Topic; Prognosis; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Survival Rate; Treatment Outcome; Uterine Cervical Neoplasms | 1999 |
Chemoradiation for carcinoma of the cervix: advances and opportunities.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Hysterectomy; Lung Neoplasms; Mitomycin; Prospective Studies; Radiation Tolerance; Radiation-Sensitizing Agents; Randomized Controlled Trials as Topic; Survival Rate; Treatment Outcome; Uterine Cervical Neoplasms; Vincristine | 2000 |
[Concomitant radiochemotherapy in cancer of the cervix uteri: modifications of the standards].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Hydroxyurea; Hysterectomy; Metaplasia; Neoplasm Staging; Patient Selection; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Survival Analysis; Uterine Cervical Neoplasms | 2000 |
Intensive concurrent chemoradiotherapy for head and neck cancer with 5-Fluorouracil- and hydroxyurea-based regimens: reversing a pattern of failure.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Education, Medical, Continuing; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Staging; Prognosis; Radiation Dosage; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Salvage Therapy; Survival Analysis; Treatment Failure; Treatment Outcome | 2003 |
Combined chemotherapy and radiation therapy for cervical cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Female; Fluorouracil; Humans; Hydroxyurea; Mitomycin; Nitroimidazoles; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms | 2004 |
68 trial(s) available for fluorouracil and hydroxyurea
| Article | Year |
|---|---|
[Chemotherapy of advanced prostate cancer].
Topics: Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Dacarbazine; Diethylstilbestrol; Drug Evaluation; Drug Therapy, Combination; Estramustine; Fluorouracil; Humans; Hydroxyurea; Male; National Health Programs; Neoplasm Recurrence, Local; Prednisolone; Procarbazine; Prognosis; Prostatic Neoplasms; Streptozocin; Time Factors; United States | 1977 |
Favorable long-term survival following induction chemotherapy with cisplatin, fluorouracil, and leucovorin and concomitant chemoradiotherapy for locally advanced head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Leucovorin; Male; Methotrexate; Middle Aged; Radiography; Time Factors; Treatment Outcome | 1992 |
Survival and analysis of failure following hydroxyurea, 5-fluorouracil and concomitant radiation therapy in poor prognosis head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Prognosis; Radiotherapy Dosage; Survival Rate | 1991 |
5-Fluorouracil, leucovorin, hydroxyurea, and escalating doses of continuous-infusion cisplatin with concomitant radiotherapy: a clinical and pharmacologic study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Leucovorin; Lung Neoplasms; Male; Middle Aged; Platinum | 1992 |
Dual modulation of 5-fluorouracil using leucovorin and hydroxyurea. A phase I trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Evaluation; Female; Fluorouracil; Humans; Hydroxyurea; Infusion Pumps; Leucovorin; Male; Middle Aged; Neoplasms; Stomatitis | 1991 |
Preliminary report of high dose folinic acid and 5-fluorouracil alone or combined with hydroxyurea in advanced colorectal cancer: a randomized trial of the Italian Oncology Group for Clinical Research.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Hydroxyurea; Leucovorin; Male; Middle Aged | 1991 |
A phase I study of a combination of allopurinol, 5-fluorouracil and leucovorin followed by hydroxyurea in patients with advanced gastrointestinal and breast cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Digestive System Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Hydroxyurea; Leucovorin; Male; Middle Aged | 1991 |
Induction chemotherapy with cisplatinum, 5-fluorouracil, bleomycin, mitomycin C and hydroxyurea for previously untreated locally advanced squamous cell carcinomas of the head and neck.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Mitomycin; Mitomycins; Neck Dissection; Neoplasm Staging | 1989 |
Chemotherapy of large bowel carcinoma--fluorouracil (FU) + hydroxyurea (HU) vs. methyl-CCNU, oncovin, fluorouracil, and streptozotocin (MOF-Strep). An Eastern Cooperative Oncology Group study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Hydroxyurea; Kidney Diseases; Male; Middle Aged; Neutropenia; Prospective Studies; Random Allocation; Rectal Neoplasms; Semustine; Streptozocin; Vincristine; Vomiting | 1985 |
Advanced lung cancer: A clinical trial of radiotherapy plus two drug combination regimens.
Topics: Adenocarcinoma; Amides; Antineoplastic Agents; Carcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Drug Therapy, Combination; Fluorouracil; Humans; Hydroxyurea; Imidazoles; Lung Neoplasms; Mechlorethamine; Nitrosourea Compounds; Radioisotope Teletherapy; Remission, Spontaneous; Triazenes; Vincristine | 1973 |
Combined radiotherapy and chemotherapy of lymphomas and other cancers.
Topics: Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Fluorouracil; Follow-Up Studies; Hematopoietic System; Hodgkin Disease; Humans; Hydroxyurea; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Placebos; Vincristine | 1971 |
[The so-called partial synchronization in the treatment of malignant lymphomas. A clinical study].
Topics: Bleomycin; Cell Division; Clinical Trials as Topic; Cytarabine; Doxorubicin; Fluorouracil; Hodgkin Disease; Humans; Hydroxyurea; Lymphoma; Neoplasm Invasiveness; Remission, Spontaneous; Vinca Alkaloids | 1980 |
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Mechlorethamine; Mercaptopurine; Methotrexate; Procarbazine; Vinblastine | 1980 |
Chemotherapy of advanced colorectal carcinoma: fluorouracil alone vs. two drug combinations using fluorouracil, hydroxyurea, semustine, dacarbazine, razoxane, and mitomycin. A phase III trial by the Eastern Cooperative Oncology Group (EST: 1278).
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Dacarbazine; Drug Administration Schedule; Female; Fluorouracil; Gastrointestinal Diseases; Hematologic Diseases; Humans; Hydroxyurea; Male; Middle Aged; Mitomycins; Random Allocation; Razoxane; Rectal Neoplasms; Semustine; Time Factors | 1984 |
Preliminary research on the evaluation of some prognostic factors in a randomized study of adjuvant immunochemotherapy in colorectal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Hydroxyurea; Male; Middle Aged; Mitomycin; Mitomycins; Prognosis; Rectal Neoplasms; Semustine | 1984 |
Combination chemotherapy of advanced colorectal cancer utilizing 5-fluorouracil, semustine, dacarbazine, vincristine, and hydroxyurea: a phase III trial by the Eastern Cooperative Oncology Group (EST: 4275).
Topics: Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Dacarbazine; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hydroxyurea; Male; Middle Aged; Nausea; Rectal Neoplasms; Semustine; Thrombocytopenia; Vincristine | 1982 |
Primary intracranial gliomas: clinical studies and treatment regimens of the Brain Tumor Research Center, University of California, San Francisco, 1977-1979.
Topics: Antineoplastic Agents; Brain Neoplasms; California; Carmustine; Clinical Trials as Topic; Drug Therapy, Combination; Fluorouracil; Follow-Up Studies; Glioma; Humans; Hydroxyurea; Lomustine; Neoplasm Recurrence, Local; Procarbazine; Vincristine | 1981 |
Intensified concomitant chemoradiotherapy with and without filgrastim for poor-prognosis head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Cohort Studies; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Filgrastim; Fluorouracil; Granulocyte Colony-Stimulating Factor; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Recombinant Proteins; Survival Analysis | 1994 |
A phase I trial of concomitant chemoradiotherapy with cisplatin dose intensification and granulocyte-colony stimulating factor support for advanced malignancies of the chest.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Cohort Studies; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Lung Neoplasms; Male; Middle Aged; Neutropenia; Recombinant Proteins; Remission Induction; Thoracic Neoplasms; Thrombocytopenia | 1995 |
Induction chemotherapy followed by concomitant chemoradiotherapy for advanced head and neck cancer: impact on the natural history of the disease.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Leucovorin; Male; Middle Aged; Proportional Hazards Models; Recombinant Proteins; Remission Induction; Survival Rate | 1995 |
Weekly levofolinic acid and 5-fluorouracil plus hydroxyurea in metastatic gastrointestinal adenocarcinomas.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Hydroxyurea; Leucovorin; Male; Middle Aged; Survival Analysis | 1994 |
Time-dose relationship for local tumor control following alternate week concomitant radiation and chemotherapy of advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Multivariate Analysis; Radiotherapy Dosage; Regression Analysis; Time Factors | 1994 |
Pilot study of 6 weeks of chemoradiotherapy with 5 FU and hydroxyurea in malignant gliomas.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Female; Fluorouracil; Gastrointestinal Diseases; Glioblastoma; Hematologic Diseases; Humans; Hydroxyurea; Life Tables; Male; Middle Aged; Nervous System Diseases; Pilot Projects; Prognosis; Radiotherapy, High-Energy; Treatment Outcome | 1993 |
5-Fluorouracil, hydroxyurea and escalating doses of iododeoxyuridine with concomitant radiotherapy for malignant gliomas: a clinical and pharmacologic analysis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Fluorouracil; Glioblastoma; Humans; Hydroxyurea; Idoxuridine; Male; Middle Aged; Remission Induction | 1993 |
Preclinical and clinical evaluation of 5-fluorouracil biochemical modulation with folinic acid and hydroxyurea for patients with colorectal carcinoma.
Topics: Antimetabolites, Antineoplastic; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Hydroxyurea; Immunologic Factors; Leucovorin; Patient Selection; Survival Analysis; Treatment Outcome; Tumor Cells, Cultured | 1995 |
Hydroxyurea may increase the activity of fluorouracil plus folinic acid in advanced gastrointestinal cancer: phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Hydroxyurea; Leucovorin; Male; Middle Aged | 1996 |
Dual modulation of 5-fluorouracil with folinic acid and hydroxyurea in metastatic colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Drug Interactions; Female; Fluorouracil; Humans; Hydroxyurea; Leucovorin; Male; Middle Aged | 1996 |
Phase I trial of high-dose infusional hydroxyurea, high-dose infusional 5-fluorouracil and recombinant interferon-alpha-2a in patients with advanced malignancies.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Hydroxyurea; Infusions, Intravenous; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Neoplasms; Recombinant Proteins | 1996 |
Treatment of advanced adenocarcinomas of the exocrine pancreas and the gallbladder with 5-fluorouracil, high dose levofolinic acid and oral hydroxyurea on a weekly schedule. Results of a multicenter study of the Southern Italy Oncology Group (G.O.I.M.).
Topics: Adenocarcinoma; Administration, Oral; Aged; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Disease Progression; Drug Administration Schedule; Female; Fluorouracil; Gallbladder Neoplasms; Humans; Hydroxyurea; Infusions, Intravenous; Injections, Intravenous; Italy; Leucovorin; Leukopenia; Male; Middle Aged; Pancreatic Neoplasms; Remission Induction; Survival Rate | 1996 |
Re-irradiation with concomitant chemotherapy of unresectable recurrent head and neck cancer: a potentially curable disease.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy; Survival Analysis; Treatment Outcome | 1996 |
Continuous infusion paclitaxel, 5-fluorouracil, and hydroxyurea with concomitant radiotherapy in patients with advanced or recurrent head and neck cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Schedule; Feasibility Studies; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Remission Induction | 1997 |
Concomitant chemoradiotherapy followed, where feasible, by surgery for cancer of the esophagus.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Drug Administration Schedule; Esophageal Neoplasms; Female; Fluorouracil; Humans; Hydroxyurea; Male; Middle Aged; Multivariate Analysis; Radiotherapy, Adjuvant; Survival Analysis; Treatment Outcome | 1997 |
TPDC-FuHu chemotherapy for the treatment of recurrent metastatic brain tumors.
Topics: Adenocarcinoma; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Disease Progression; Female; Fluorouracil; Humans; Hydroxyurea; Lomustine; Lung Neoplasms; Male; Middle Aged; Mitolactol; Procarbazine; Prospective Studies; Thioguanine | 1997 |
Hydroxyurea, 5-fluorouracil infusion, and cisplatin adjunct to radiation therapy in cervical carcinoma: a phase I-II trial of the Gynecologic Oncology Group.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Humans; Hydroxyurea; Infusions, Parenteral; Middle Aged; Uterine Cervical Neoplasms | 1997 |
Clinical benefit with cisplatin, hydroxyurea and 5-fluorouracil/leucovorin in advanced pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; Hydroxyurea; Male; Middle Aged; Palliative Care; Pancreatic Neoplasms | 1997 |
Phase I study of concomitant chemoradiotherapy with paclitaxel, fluorouracil, and hydroxyurea with granulocyte colony-stimulating factor support for patients with poor-prognosis cancer of the head and neck.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Paclitaxel; Prognosis | 1998 |
Induction chemotherapy followed by concurrent chemoradiation for advanced head and neck cancer: improved disease control and survival.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Leucovorin; Levoleucovorin; Male; Middle Aged; Radiotherapy Dosage; Recombinant Proteins; Remission Induction; Survival Rate | 1998 |
High-dose folinic acid and 5-fluorouracil alone or combined with hydroxyurea in advanced colorectal cancer: a randomized trial of the Italian Oncology Group for Clinical Research.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Hydroxyurea; Leucovorin; Male; Middle Aged; Survival Analysis | 1998 |
Phase I trial of concomitant chemoradiotherapy for cervical cancer and other advanced pelvic malignancies.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouracil; Humans; Hydroxyurea; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Radiotherapy; Time Factors; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Vaginal Neoplasms | 1999 |
Radiation therapy with concomitant hydroxyurea and fluorouracil in stage II and III head and neck cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Intravenous; Male; Middle Aged; Neoplasm Staging; Regression Analysis | 1999 |
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinoma; Cisplatin; Combined Modality Therapy; Disease Progression; Female; Fluorouracil; Humans; Hydroxyurea; Middle Aged; Neoplasm Staging; Survival Analysis; Uterine Cervical Neoplasms | 1999 |
Paclitaxel, 5-fluorouracil, hydroxyurea, and concomitant radiation therapy for poor-prognosis head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Paclitaxel; Survival Analysis; Treatment Outcome | 1999 |
A phase II study of the modulation of 5-fluorouracil and folinic acid with high-dose infusional hydroxyurea in metastatic colorectal carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Hydroxyurea; Infusions, Intravenous; Leucovorin; Male; Middle Aged; Nucleic Acid Synthesis Inhibitors; Prognosis; Survival Rate; Treatment Outcome | 1999 |
Phase II/pharmacodynamic trial of dose-intensive, weekly parenteral hydroxyurea and fluorouracil administered with interferon alfa-2a in patients with refractory malignancies of the gastrointestinal tract.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Deoxyuracil Nucleotides; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Leukocytes, Mononuclear; Male; Middle Aged; Pancreatic Neoplasms; Prospective Studies; Recombinant Proteins; Stomach Neoplasms; Thymine Nucleotides; Treatment Outcome | 1999 |
Concomitant chemoradiotherapy as primary therapy for locoregionally advanced head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease Progression; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Male; Quality of Life; Radiotherapy; Radiotherapy Dosage; Recombinant Proteins; Survival Rate; Tretinoin | 2000 |
A phase I-II study of concomitant chemoradiotherapy with paclitaxel (one-hour infusion), 5-fluorouracil and hydroxyurea with granulocyte colony stimulating factor support for patients with poor prognosis head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Paclitaxel; Prognosis; Recombinant Proteins | 2000 |
Concomitant infusional paclitaxel and fluorouracil, oral hydroxyurea, and hyperfractionated radiation for locally advanced squamous head and neck cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Dose Fractionation, Radiation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Illinois; Infusions, Intravenous; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Quality of Life; Survival Analysis | 2001 |
Full dose reirradiation combined with chemotherapy after salvage surgery in head and neck carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy; Risk Factors; Salvage Therapy; Survival Analysis | 2001 |
RTOG 96-10: reirradiation with concurrent hydroxyurea and 5-fluorouracil in patients with squamous cell cancer of the head and neck.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Survival Rate | 2001 |
Phase 1 trial of combined chemotherapy and reirradiation for recurrent unresectable head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Intravenous; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy Dosage; Treatment Outcome | 2003 |
Induction chemotherapy followed by concomitant chemoradiotherapy in the treatment of locoregionally advanced nasopharyngeal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Humans; Hydroxyurea; Interferon-alpha; Leucovorin; Male; Middle Aged; Nasopharyngeal Neoplasms; Neoadjuvant Therapy; Neoplasm Staging; Treatment Outcome | 2003 |
Multicenter randomized Phase II study of paclitaxel (1-hour infusion), fluorouracil, hydroxyurea, and concomitant twice daily radiation with or without erythropoietin for advanced head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Administration Schedule; Erythropoietin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Paclitaxel; Recombinant Proteins; Survival Rate; Treatment Outcome | 2003 |
Bimonthly leucovorin, infusion 5-fluorouracil, hydroxyurea, and irinotecan (FOLFIRI-2) for pretreated metastatic colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Hydroxyurea; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Survival Analysis | 2003 |
Phase II clinical trial of parenteral hydroxyurea in combination with fluorouracil, interferon and filgrastim in the treatment of advanced pancreatic, gastric and neuroendocrine tumors.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Filgrastim; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Hydroxyurea; Infusions, Intravenous; Injections, Subcutaneous; Interferons; Male; Middle Aged; Neoplasm Metastasis; Neuroendocrine Tumors; Pancreatic Neoplasms; Recombinant Proteins; Stomach Neoplasms; Treatment Outcome | 2004 |
Preliminary results of Radiation Therapy Oncology Group 97-03: a randomized phase ii trial of concurrent radiation and chemotherapy for advanced squamous cell carcinomas of the head and neck.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Feasibility Studies; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Staging; Paclitaxel; Radiotherapy Dosage; Survival Analysis; Treatment Outcome | 2004 |
Paclitaxel, 5-fluorouracil and hydroxyurea concurrent with radiation in locally advanced nasopharyngeal carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Humans; Hydroxyurea; Male; Middle Aged; Nasopharyngeal Neoplasms; Paclitaxel; Survival Analysis; Treatment Failure | 2006 |
High survival and organ function rates after primary chemoradiotherapy for intermediate-stage squamous cell carcinoma of the head and neck treated in a multicenter phase II trial.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Disease-Free Survival; Dose Fractionation, Radiation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Staging; Neoplasms, Second Primary; Quality of Life; Radiotherapy Dosage; Radiotherapy, Adjuvant; Surveys and Questionnaires; Survival Analysis; Treatment Outcome | 2006 |
Final report of RTOG 9610, a multi-institutional trial of reirradiation and chemotherapy for unresectable recurrent squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Dose Fractionation, Radiation; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Prospective Studies; Radiotherapy, Adjuvant; Retreatment; Survival Rate | 2008 |
A phase I trial of docetaxel based induction and concomitant chemotherapy in patients with locally advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Docetaxel; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Maximum Tolerated Dose; Middle Aged; Survival Analysis; Taxoids | 2007 |
Phase I study of bevacizumab added to fluorouracil- and hydroxyurea-based concomitant chemoradiotherapy for poor-prognosis head and neck cancer.
Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Maximum Tolerated Dose; Middle Aged; Prognosis; Radiotherapy; Survival Analysis; Survival Rate | 2008 |
Induction chemotherapy and concurrent chemoradiotherapy for locoregionally advanced head and neck cancer: a multi-institutional phase II trial investigating three radiotherapy dose levels.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cohort Studies; Combined Modality Therapy; Disease-Free Survival; Dose-Response Relationship, Radiation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Staging; Paclitaxel; Remission Induction | 2008 |
Randomized trial of postoperative reirradiation combined with chemotherapy after salvage surgery compared with salvage surgery alone in head and neck carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality Therapy; Disease Progression; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Neoplasm Metastasis; Postoperative Period; Recurrence; Salvage Therapy; Treatment Outcome | 2008 |
Phase 2 trial of concurrent 5-fluorouracil, hydroxyurea, cetuximab, and hyperfractionated intensity-modulated radiation therapy for locally advanced head and neck cancer.
Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Quality of Life; Radiotherapy, Intensity-Modulated | 2011 |
A randomized phase II study of 5-fluorouracil, hydroxyurea, and twice-daily radiotherapy compared with bevacizumab plus 5-fluorouracil, hydroxyurea, and twice-daily radiotherapy for intermediate-stage and T4N0-1 head and neck cancers.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Squamous Cell; Combined Modality Therapy; Disease Progression; Disease-Free Survival; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Staging; Radiotherapy Dosage; Squamous Cell Carcinoma of Head and Neck | 2011 |
Prognostic significance of p16 in locoregionally advanced head and neck cancer treated with concurrent 5-fluorouracil, hydroxyurea, cetuximab and intensity-modulated radiation therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Combined Modality Therapy; Cyclin-Dependent Kinase Inhibitor p16; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Staging; Prognosis; Radiotherapy, Intensity-Modulated; Survival Analysis; Treatment Outcome; Young Adult | 2012 |
Performance and quality of life outcomes for T4 laryngeal cancer patients treated with induction chemotherapy followed by chemoradiotherapy.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemoradiotherapy; Female; Fluorouracil; Humans; Hydroxyurea; Induction Chemotherapy; Laryngeal Neoplasms; Male; Middle Aged; Paclitaxel; Quality of Life; Risk Factors; Time Factors; Treatment Outcome | 2012 |
A phase I dose escalation study of Ad GV.EGR.TNF.11D (TNFerade™ Biologic) with concurrent chemoradiotherapy in patients with recurrent head and neck cancer undergoing reirradiation.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; DNA; Dose Fractionation, Radiation; Female; Fluorouracil; Genetic Therapy; Head and Neck Neoplasms; Humans; Hydroxyurea; Kaplan-Meier Estimate; Male; Maximum Tolerated Dose; Middle Aged; Radiation-Sensitizing Agents; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated; Retreatment; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2013 |
Phase III randomized trial of induction chemotherapy in patients with N2 or N3 locally advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Docetaxel; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Induction Chemotherapy; Male; Middle Aged; Squamous Cell Carcinoma of Head and Neck; Survival Rate; Taxoids | 2014 |
154 other study(ies) available for fluorouracil and hydroxyurea
| Article | Year |
|---|---|
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Synthesis of acyclonucleoside hydroxamic acids as inhibitors of ribonucleotide reductase.
Topics: Antineoplastic Agents; Chemical Phenomena; Chemistry; HeLa Cells; Humans; Hydroxamic Acids; Nucleosides; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases | 1989 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Synthesis, aerobic cytotoxicity, and radiosensitizing activity of novel 2,4-dinitrophenylamine tethered 5-fluorouracil and hydroxyurea.
Topics: Aerobiosis; Cell Survival; Fluorouracil; HT29 Cells; Humans; Hydroxyurea; Molecular Structure; Nitro Compounds; Radiation-Sensitizing Agents; Structure-Activity Relationship | 2006 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Organization of haemopoietic stem cells: the generation-age hypothesis.
Topics: Animals; Antigens; Cell Division; Cell Survival; Cesium Radioisotopes; Colony-Forming Units Assay; Endotoxins; Female; Fluorouracil; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Hydroxyurea; Male; Mice; Phenylhydrazines; Salmonella typhi; Transplantation, Homologous | 1979 |
Kinetically-based multiple drug treatment for advanced head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Ear Neoplasms; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Laryngeal Neoplasms; Maxillary Neoplasms; Mercaptopurine; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasms; Tongue Neoplasms; Tonsillar Neoplasms; Vincristine | 1975 |
Enhancing effect by metabolic inhibitors on the killing of tumor cells by antibody and complement.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cells, Cultured; Complement System Proteins; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Fluorouracil; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms, Experimental; Puromycin; Vincristine | 1975 |
Hair growth inhibition as a method of screening drugs for local antimitotic activity.
Topics: Animals; Antineoplastic Agents; Bleomycin; Colchicine; Cyclophosphamide; Cytarabine; Drug Evaluation, Preclinical; Fluorouracil; Guinea Pigs; Hair; Hydroxyurea; Injections, Intradermal; Mechlorethamine; Methotrexate; Mitosis; Thiotepa; Vincristine | 1977 |
Chemotherapy for oral malignant disease.
Topics: Antineoplastic Agents; Bleomycin; Drug Therapy, Combination; Fluorouracil; Humans; Hydroxyurea; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms; Prognosis; Vinblastine | 1979 |
The chemotherapy of urologic cancer.
Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Doxorubicin; Drug Therapy, Combination; Estradiol; Female; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Kidney Neoplasms; Male; Methotrexate; Middle Aged; Mitomycins; Plicamycin; Prostatic Neoplasms; Testicular Neoplasms; Thiotepa; Urinary Bladder Neoplasms; Urogenital Neoplasms; Vincristine | 1975 |
Metabolism of 5-fluorouracil in sensitive and resistant Novikoff hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Deoxyuridine; DNA Replication; Drug Resistance; Fluorouracil; Hydroxyurea; Kinetics; Liver Neoplasms; Mutation; Neoplasms, Experimental; Rats; RNA, Ribosomal; Transcription, Genetic | 1977 |
Gibberellic acid-induced germination of spores of Anemia phyllitidis: autoradiographic study of the timing and regulation of nucleic acid and protein synthesis in relation to cell morphogenesis.
Topics: Autoradiography; Cycloheximide; Dactinomycin; Deoxyadenosines; DNA; Fluorouracil; Gibberellins; Hydroxyurea; Plant Development; Plant Proteins; RNA; Spores | 1977 |
Inhibition of DNA synthesis in Harding-Passey melanoma cells by prostaglandins A1 and A2: comparison with chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; DNA Replication; DNA, Neoplasm; Doxorubicin; Fluorouracil; Hydroxyurea; Kinetics; Melanoma; Mice; Neoplasms, Experimental; Prostaglandins A | 1979 |
Sequential 5-fluorouracil and hydroxyurea therapy for metastatic colorectal adenocarcinoma.
Topics: Adenocarcinoma; Colonic Neoplasms; Fluorouracil; Humans; Hydroxyurea; Neoplasm Metastasis; Rectal Neoplasms | 1978 |
[Resistance testing and chemotherapy results of bronchial tumours (author's transl)].
Topics: Bronchial Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Resistance; Fluorouracil; Humans; Hydroxyurea; Methotrexate; Prognosis; Remission, Spontaneous; Vincristine | 1978 |
A new anti-cancer principle isolated from Gymnosporia rothiana Laws, and its use in attaining cures in L1210 leukaemia in combination with "S" phase sensitive drugs.
Topics: Animals; Antineoplastic Agents; Cytarabine; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Hydroxyurea; Interphase; Leukemia L1210; Mice; Plants | 1978 |
Further experience with chemotherapy in the Dunning prostatic adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Hybridization, Genetic; Hydroxyurea; Lomustine; Male; Methotrexate; Neoplasms, Experimental; Platinum; Prostatic Neoplasms; Rats | 1978 |
Psoriasis: clinical aspects and management.
Topics: Administration, Topical; Age Factors; Azauridine; Fluorouracil; Humans; Hydroxyurea; Mechlorethamine; Methotrexate; Methoxsalen; Nitrosourea Compounds; Psoriasis; Thiotepa; Triamcinolone Acetonide | 1976 |
DNA synthesis in isolated lymphocyte nuclei. Effects of megaloblastic anaemia due to folate or vitamin B-12 deficiency or antimetabolite drugs.
Topics: Adenosine Triphosphate; Adult; Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Cell Nucleus; Cytarabine; DNA; DNA Replication; DNA-Directed DNA Polymerase; Ethylmaleimide; Female; Fluorouracil; Folic Acid Deficiency; Humans; Hydroxyurea; Kinetics; Lectins; Lymphocyte Activation; Lymphocytes; Male; Methotrexate; Middle Aged; Thymine Nucleotides; Vitamin B 12 Deficiency | 1977 |
[3H]Thymidine triphosphate incorporation into isolated nuclei.
Topics: Anemia, Megaloblastic; Cell Nucleus; DNA Replication; Fluorouracil; Folic Acid; Humans; Hydroxyurea; Lectins; Lymphocyte Activation; Lymphocytes; Thymine Nucleotides; Vitamin B 12 | 1976 |
Changes in cell age cohort composition of tumors and normal tissues by radiation and chemotherapy.
Topics: Animals; Cell Survival; Cell Transformation, Neoplastic; Fluorouracil; Hydroxyurea; Mice; Splenic Neoplasms; Time Factors | 1976 |
[Possibilities and limits of pre-therapeutic neoplasm sensitivity cytostatics tests under short-term conditions].
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cricetinae; Cyclophosphamide; Dactinomycin; Daunorubicin; Disease Models, Animal; DNA, Neoplasm; Doxorubicin; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Hydroxyurea; Male; Methotrexate; Mice; Procarbazine; Rats; RNA, Neoplasm; Time Factors; Triaziquone; Vincristine | 1975 |
Combined 5-fluorouracil and hydroxyurea therapy for gastrointestinal cancer.
Topics: Administration, Oral; Ataxia; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Humans; Hydroxyurea; Injections, Intravenous; Leukopenia; Neoplasm Metastasis; Pancreatic Neoplasms; Rectal Neoplasms | 1975 |
Treatment of recurrent gliomas and metastatic brain tumors with a polydrug protocol designed to combat nitrosourea resistance.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Cycle; Child; Child, Preschool; Drug Resistance; Female; Fluorouracil; Glioblastoma; Glioma; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Recurrence, Local; Nitrosourea Compounds | 1992 |
Hydroxyurea modulates 5-fluorouracil antineoplastic activity in advanced head and neck carcinoma pretreated with chemotherapy.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Survival Rate | 1992 |
The interaction of 5-fluorouracil, hydroxyurea, and radiation in two human head and neck cancer cell lines.
Topics: Cell Survival; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; S Phase; Tumor Cells, Cultured | 1992 |
Joint actions of developmental toxicants in Xenopus embryos: binary mixtures of DNA synthesis inhibitors.
Topics: Animals; Cytarabine; DNA; Drug Synergism; Embryo, Nonmammalian; Fluorouracil; Hydroxyurea; Teratogens; Xenopus laevis | 1992 |
Treatment of recurrent head and neck cancer with 5-fluorouracil, hydroxyurea, and reirradiation.
Topics: Adult; Aged; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Survival Rate | 1992 |
Concomitant chemoradiotherapy with cisplatin, 5-fluorouracil and hydroxyurea in poor-prognosis head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Middle Aged; Prognosis; Remission Induction; Salvage Therapy; Survival Rate; Treatment Outcome | 1992 |
Hydroxyurea with concomitant radiotherapy for locally advanced head and neck cancer.
Topics: Administration, Oral; Bone Marrow; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Intravenous; Neoplasm Recurrence, Local; Radiation-Sensitizing Agents; Radiotherapy Dosage; Remission Induction; Stomatitis; Survival Rate | 1992 |
Induction chemotherapy with a new regimen alternating cisplatin, fluorouracil with mitomycin, hydroxyurea and bleomycin in carcinomas of nasopharynx or other sites of the head and neck region.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Mitomycins; Nasopharyngeal Neoplasms; Neoplasm Staging; Remission Induction; Survival Rate | 1990 |
A phase I study of cisplatin, 5-fluorouracil and leucovorin with escalating doses of hydroxyurea in chemotherapy naive patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Leucovorin; Male; Middle Aged | 1991 |
High-dose melphalan with 6-hydroxydopamine-purged autologous bone marrow transplantation for poor-risk neuroblastoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dianhydrogalactitol; Doxorubicin; Female; Fluorouracil; Humans; Hydroxydopamines; Hydroxyurea; Infant; Male; Melphalan; Neoplasm Staging; Neuroblastoma; Oxidopamine; Prognosis; Radiotherapy Dosage; Remission Induction; Survival Rate; Vincristine; Whole-Body Irradiation | 1991 |
Selective uptake of toxic nucleoside (125IUdR) by resistant cancer.
Topics: Adenocarcinoma; Animals; Cell Line; Choriocarcinoma; Colon; Colonic Neoplasms; Cytarabine; Drug Resistance; Female; Fluorouracil; Humans; Hydroxyurea; Idoxuridine; Iodine Radioisotopes; Male; Methotrexate; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Uterine Neoplasms | 1991 |
5-Fluorouracil with oral leucovorin and hydroxyurea and concomitant radiotherapy for stage III non-small cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Follow-Up Studies; Humans; Hydroxyurea; Leucovorin; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Radiotherapy Dosage | 1990 |
[Combined therapy of locally advanced squamous epithelial cancers in the area of the head and neck].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Mitomycin; Mitomycins | 1988 |
Postcricoid carcinoma: a retrospective study of 13 patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Hydroxyurea; Laryngeal Neoplasms; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Vincristine | 1985 |
Hydroxyurea, fluorouracil, and concomitant radiotherapy in poor-prognosis head and neck cancer: a phase I-II study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma; Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Evaluation; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Prognosis; Stomatitis | 1989 |
Biochemical rationale for the synergism of 5-fluorouracil and folinic acid.
Topics: Animals; Cell Division; Cell Survival; Deoxyuracil Nucleotides; Drug Synergism; Floxuridine; Fluorouracil; Hydroxyurea; Leucovorin; Leukemia L1210; Mice; Structure-Activity Relationship; Tumor Cells, Cultured | 1987 |
Phase II study of combined carmustine, 5-fluorouracil, hydroxyurea, and 6-mercaptopurine (BFHM) for the treatment of malignant gliomas.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Drug Evaluation; Fluorouracil; Glioblastoma; Glioma; Humans; Hydroxyurea; Mercaptopurine; Middle Aged; Neurologic Examination; Statistics as Topic; Tomography, X-Ray Computed | 1986 |
cis-platinum, 5-fluorouracil, and hydroxyurea in the treatment of advanced non-small-cell lung cancer. A phase II study.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Drug Synergism; Drug Tolerance; Fluorouracil; Humans; Hydroxyurea; Lung Neoplasms; Middle Aged | 1987 |
Concomitant hydroxyurea, 5-fluorouracil, and radiation therapy for recurrent head and neck cancer: early results.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy Dosage; Radiotherapy, High-Energy | 1988 |
Coordinated use of sequentially escalated cyclophosphamide and cell-cycle-specific chemotherapy (N4SE protocol) for advanced neuroblastoma: experience with 100 patients.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cell Cycle; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Hydroxyurea; Infant; Male; Neuroblastoma; Time Factors; Vincristine | 1987 |
DNA repair following incorporation of 5-fluorouracil into DNA of mouse bone marrow cells.
Topics: Animals; Bone Marrow; Bone Marrow Cells; DNA; DNA Damage; DNA Repair; DNA Replication; DNA, Single-Stranded; Fluorouracil; Hydroxyurea; Male; Mice | 1988 |
Treatment of recurrent brain stem gliomas and other central nervous system tumors with 5-fluorouracil, CCNU, hydroxyurea, and 6-mercaptopurine.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Ependymoma; Female; Fluorouracil; Glioma; Humans; Hydroxyurea; Lomustine; Male; Mercaptopurine; Neoplasm Recurrence, Local; Spinal Cord Neoplasms | 1988 |
Sequential inhibitory effects of antitumor agents related to levodopa and dopamine upon DNA synthetic enzymes.
Topics: Animals; Antineoplastic Agents; Dopamine; Fluorouracil; Hydroxyurea; Kinetics; Leukemia L1210; Levodopa; Mice; Ribonucleotide Reductases; Thymidylate Synthase | 1986 |
A cytotoxic DNA precursor is taken up selectively by human cancer xenografts.
Topics: Animals; Choriocarcinoma; Colon; DNA; Female; Fluorouracil; Humans; Hydroxyurea; Idoxuridine; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Nucleic Acid Precursors; Pregnancy; Uterine Neoplasms | 1987 |
Coadministration of methylxanthines and inhibitor compounds potentiates teratogenicity in Xenopus embryos.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Cycloheximide; Cytarabine; Drug Synergism; Embryo, Nonmammalian; Emetine; Fluorouracil; Hydroxyurea; Theobromine; Theophylline; Xanthines; Xenopus laevis | 1987 |
Phase II study of a combination of hydroxyurea, fluorouracil and mitomycin in previously treated squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Mitomycins | 1986 |
Chemosensitivity of human head and neck cancer xenografts in the clonogenic assay and in nude mice.
Topics: Animals; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; In Vitro Techniques; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Rats; Tumor Stem Cell Assay | 1986 |
Clonogenic response of cells of murine intestinal crypts to 12 cytotoxic drugs.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Survival; Clone Cells; Dose-Response Relationship, Drug; Fluorouracil; Hydroxyurea; Intestinal Mucosa; Male; Methotrexate; Mice; Mice, Inbred Strains; Vincristine | 1985 |
Factors modifying cytotoxicity induced by 5-FU and hydroxyurea.
Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; Cell Survival; Culture Media; DNA; Flow Cytometry; Fluorouracil; Hydroxyurea; Rats; Sister Chromatid Exchange; Time Factors | 1985 |
Chemotherapy of vesical and prostatic tumours.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Cobalt Isotopes; Cystitis; Daunorubicin; Ethoglucid; Fluorouracil; Humans; Hydroxyurea; Male; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Papilloma; Prostatic Neoplasms; Thiotepa; Urinary Bladder Neoplasms | 1971 |
Chemotherapy of lung cancer: the experience of the National Cancer Institute of Milan.
Topics: Adenocarcinoma; Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Doxorubicin; Fluorouracil; Humans; Hydroxyurea; Italy; Lung Neoplasms; Methotrexate; Procarbazine; Remission, Spontaneous | 1973 |
Chemotherapy in recurrent heat and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Injections, Intra-Arterial; Injections, Intramuscular; Methotrexate; Neoplasm Recurrence, Local; Neoplasms; Vinblastine; Vincristine | 1974 |
[Palliative chemotherapy of bronchial cancers. Current status of the problem].
Topics: Antineoplastic Agents; Bleomycin; Bronchial Neoplasms; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Emetine; Fluorouracil; Humans; Hydroxyurea; Methotrexate; Mitomycins; Mustard Compounds; Palliative Care; Procarbazine; Thiotepa; Vinblastine | 1973 |
Chemotherapy of induced skin tumors in mice.
Topics: Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Benz(a)Anthracenes; Busulfan; Carcinoma, Squamous Cell; Chlorambucil; Cortisone; Cyclophosphamide; Dactinomycin; Estradiol; Female; Fluorouracil; Hydroxyurea; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nitroso Compounds; Papilloma; Skin Neoplasms; Testosterone; Triethylenemelamine | 1968 |
Malignant hepatoma in the Bantu.
Topics: Adenoma, Bile Duct; Africa, Eastern; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Black People; Blood Proteins; Carcinoma, Hepatocellular; Clinical Enzyme Tests; Cyclophosphamide; Cytarabine; Dactinomycin; Fluorouracil; gamma-Globulins; Humans; Hydroxyurea; Liver Neoplasms; Male; Mercaptopurine; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Prednisone; Prognosis; South Africa; Vincristine | 1970 |
Comparison of the effects of several inhibitors of the synthesis of nucleic acids upon the viability and progression through the cell cycle of cultured H. Ep. no. 2 cells.
Topics: Antimetabolites; Azaguanine; Carcinoma; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA Replication; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Laryngeal Neoplasms; Mercaptopurine; Methotrexate; Mitosis; Ribonucleosides; Thioguanine; Time Factors; Tritium | 1972 |
Enhancement of the antitumor activity of 5-fluorouracil by drug combinations.
Topics: Animals; Body Weight; Carcinoma, Ehrlich Tumor; Cell Count; Floxuridine; Fluorouracil; Hydroxyurea; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Time Factors; Transplantation, Homologous; Vinblastine | 1973 |
[Effect of hydroxyurea and 5-fluorouracil on enzyme pattern and ultrastructure of liver, kidney, and pancreas in rats (author's transl)].
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Electron Transport Complex IV; Fluorouracil; Glucosephosphate Dehydrogenase; Histocytochemistry; Hydroxyurea; Kidney; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Liver; Liver Glycogen; Male; Microscopy, Electron; Nucleotidases; Organ Specificity; Pancreas; Succinate Dehydrogenase; Time Factors | 1974 |
Nucleic acid and protein synthesis and pattern regulation in hydra. II. Effect of inhibition of nucleic acid and protein synthesis on hypostome formation.
Topics: Animals; Chloramphenicol; Cnidaria; Cytosine; Dactinomycin; DNA; Fluorouracil; Hydroxyurea; Morphogenesis; Protein Biosynthesis; RNA; RNA, Messenger; Thymidine; Transplantation; Tritium; Uridine | 1969 |
Cancer of the gastrointestinal tract. Chemotherapy.
Topics: Antineoplastic Agents; Camptothecin; Carmustine; Cyclohexanes; Cyclophosphamide; Drug Therapy, Combination; Fluorometholone; Fluorouracil; Humans; Hydroxyurea; Mitomycins; Nitrosourea Compounds; Remission, Spontaneous; Stomach Neoplasms; Streptonigrin; Time Factors | 1974 |
Synergism of ICRF 159 and radiotherapy in treatment of experimental tumors.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Evaluation Studies as Topic; Fluorouracil; Hydroxyurea; Male; Methotrexate; Mice; Piperazines; Propane; Radiotherapy Dosage; Sarcoma, Experimental | 1974 |
An anomalous effect of hydroxyurea and visible light on nucleic acids of a photoreactivating mammalian cell Potorous tridactylis.
Topics: Animals; Carbon Isotopes; Cells, Cultured; Deoxyribonucleosides; Depression, Chemical; DNA; Fluorouracil; Hydroxyurea; In Vitro Techniques; L Cells; Light; Marsupialia; Radiation Effects; Radiobiology; RNA; Thymidine; Tritium; Uridine | 1972 |
Hormones, chemotherapy, and the breast cancer patient.
Topics: Administration, Oral; Adrenalectomy; Adult; Aged; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Hydroxyurea; Injections, Intravenous; Menstruation; Middle Aged; Mitomycins; Neoplasm Recurrence, Local; Thiotepa | 1972 |
Pharmacodynamic principles in chemical teratology: dose-effect relationships.
Topics: Abnormalities, Drug-Induced; Adsorption; Cyclophosphamide; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Embryo, Mammalian; Female; Fluorouracil; Gestational Age; Humans; Hydroxyurea; Kinetics; Lethal Dose 50; Maternal-Fetal Exchange; Models, Biological; Pharmaceutical Preparations; Pregnancy; Receptors, Drug; Thalidomide; Time Factors | 1972 |
Unsuccessful fluorouracil treatment of recalcitrant pustular psoriasis.
Topics: Adult; Fluorouracil; Humans; Hydroxyurea; Male; Prednisone; Psoriasis | 1973 |
Age cohort variation of tumor cells.
Topics: Animals; Cell Division; Disease Models, Animal; DNA, Neoplasm; Fluorouracil; Hydroxyurea; Lymphoma; Mice; Mitosis; Models, Biological; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; RNA, Neoplasm; Thymidine; Time Factors; Tritium | 1973 |
Effect of chemotherapeutic agents on bladder cancer: a new animal model.
Topics: Animals; Antineoplastic Agents; Carcinoma, Transitional Cell; Cyclophosphamide; Dactinomycin; Diamines; Disease Models, Animal; Doxorubicin; Fluorouracil; Hydroxyurea; Lomustine; Mice; Mice, Inbred C3H; Platinum; Urinary Bladder Neoplasms | 1973 |
Androgen-induced sexual differentiation of the brain is blocked by inhibitors of DNA and RNA synthesis.
Topics: Animals; Animals, Newborn; Brain; Dactinomycin; Depression, Chemical; DNA; Estrus; Female; Fluorouracil; Gonadotropins; Hydroxyurea; Hypothalamus; Mycotoxins; Organ Size; Ovary; Ovulation; Pregnancy; Protein Biosynthesis; Puromycin; Rats; RNA; Sex Factors; Testosterone; Thymidine; Tritium | 1974 |
Systemic chemotherapy for carcinoma of the cervix.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Humans; Hydroxyurea; Mechlorethamine; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Progestins; Thiotepa; Urea; Uterine Cervical Neoplasms | 1967 |
[Basic principles of percutaneous radiotherapy in cervical lymph node metastases].
Topics: Carcinoma, Squamous Cell; Cesium Isotopes; Cobalt Isotopes; Electrons; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Iridium; Lymph Nodes; Lymphatic Metastasis; Lymphoma; Methods; Neck Dissection; Preoperative Care; Radiodermatitis; Radioisotope Teletherapy; Radioisotopes; Radiotherapy Dosage; Radiotherapy, High-Energy; Radium | 1971 |
Use of mouse vaginal and rectal epithelium to screen antimitotic effects of systemically administered drugs.
Topics: Animals; Antineoplastic Agents; Cytarabine; Epithelial Cells; Epithelium; Female; Fluorouracil; Hydroxyurea; Mechlorethamine; Methotrexate; Mice; Mitosis; Podophyllin; Rectum; Vagina; Vinblastine | 1971 |
Studies on the effects of hydroxyurea and other anticancer drugs upon pyrimidine metabolism.
Topics: Amidohydrolases; Animals; Antineoplastic Agents; Ascites; Carbon Isotopes; Cyclophosphamide; Cytarabine; Deoxyuridine; DNA; Fluorouracil; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Mice; Neoplasms, Experimental; Orotic Acid; Pyrimidines; Transferases; Triazines | 1969 |
Implications of biochemical, cytokinetic, pharmacologic, and toxicologic relationships in the design of optimal therapeutic schedules.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Disease Models, Animal; DNA, Neoplasm; Fluorouracil; Half-Life; Hydroxyurea; In Vitro Techniques; Kinetics; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Mitosis; Nitrosourea Compounds; Thiosemicarbazones | 1970 |
Intravaginal and intrarectal screening of antimitotic drugs for topical effectiveness.
Topics: Animals; Antineoplastic Agents; Colchicine; Cytarabine; Daunorubicin; Evaluation Studies as Topic; Female; Fluorouracil; Hydroxyurea; Intestinal Mucosa; Mechlorethamine; Methods; Methotrexate; Mice; Mitosis; Mucous Membrane; Nitrosourea Compounds; Podophyllin; Rectum; Vagina; Vinblastine; Vincristine | 1971 |
Studies on the mechanism of action of progesterone in regulation of the synthesis of specific protein.
Topics: Amino Acids; Animals; Chickens; Colchicine; Culture Techniques; Cycloheximide; Dactinomycin; Diethylstilbestrol; Estrogens; Female; Fluorouracil; Hydroxyurea; Mitosis; Muramidase; Ovalbumin; Oviducts; Progesterone; Protein Biosynthesis; RNA; RNA Nucleotidyltransferases; Thymidine; Tritium; Uridine | 1968 |
Treatment of carcinoma of the bladder with combined radiotherapy, chemotherapy, and surgery.
Topics: Animals; Cricetinae; Female; Fluorouracil; Humans; Hydroxyurea; Male; Mitomycins; Neoplasm Metastasis; Neoplasm Recurrence, Local; Urinary Bladder Neoplasms | 1969 |
Disseminated melanoma. Biologic behavior and treatment.
Topics: Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Dactinomycin; Fluorouracil; Humans; Hydrazines; Hydroxyurea; Lymph Node Excision; Lymphatic Metastasis; Melanoma; Melphalan; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Perfusion; Vincristine | 1967 |
5-Fluorouracil and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) followed by hydroxyurea, misonidazole, and irradiation for brain stem gliomas: a pilot study of the Brain Tumor Research Center and the Childrens Cancer Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Cobalt Radioisotopes; Combined Modality Therapy; Dose-Response Relationship, Radiation; Female; Fluorouracil; Glioblastoma; Glioma; Humans; Hydroxyurea; Lomustine; Male; Misonidazole; Prognosis; Radioisotope Teletherapy | 1984 |
Accumulation of pyrophosphate correlates with the increased level of nucleoside triphosphates in Escherichia coli.
Topics: Adenosine Triphosphate; Chromatography, High Pressure Liquid; Diphosphates; Escherichia coli; Fluorouracil; Hydroxyurea; Luminescent Measurements; Mercaptopurine; Mutation; Ribonucleotides; Species Specificity; Uracil | 1984 |
Sequential combination chemotherapy of advanced head and neck carcinoma: re-evaluation of a highly effective regimen.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Doxorubicin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Leucovorin; Male; Mercaptopurine; Methotrexate; Middle Aged; Vincristine | 1981 |
Chemotherapy programs of the National Prostatic Cancer Project (NPCP).
Topics: Antineoplastic Agents; Cyclophosphamide; Dacarbazine; Diethylstilbestrol; Drug Evaluation; Drug Therapy, Combination; Estradiol; Fluorouracil; Humans; Hydroxyurea; Male; Neoplasm Recurrence, Local; Pregnadienetriols; Procarbazine; Prostatic Neoplasms; Streptozocin | 1980 |
Evaluation of a sequential 5-FU and hydroxyurea combination in advanced bowel cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Colonic Neoplasms; Female; Fluorouracil; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms | 1984 |
Murine L5178Y cells resulting in altered drug sensitivities from fractionated radiation exposure in vitro.
Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Etoposide; Fluorouracil; Hydroxyurea; Leukemia L5178; Leukemia, Experimental; Methotrexate; Mice; Vincristine | 1984 |
Combined cytotoxic effect of low-dose 5-fluorouracil and hydroxyurea on 9L cells in vitro.
Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Hydroxyurea; Kinetics; Rats; Thymidine | 1983 |
5-Fluorouracil, vincristine and hydroxyurea combination chemotherapy in metastatic colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms; Vincristine | 1983 |
Clonal generation of multipotent and unipotent hemopoietic blast cell colonies in vitro.
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cell Division; Clone Cells; Colony-Forming Units Assay; Fluorouracil; Hematopoietic Stem Cells; Hydroxyurea; Mice; Mice, Inbred CBA | 1984 |
Gastric cancer-survival at the Pennsylvania Hospital with and without adjuvant chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Gastrectomy; Humans; Hydroxyurea; Male; Middle Aged; Pennsylvania; Prognosis; Stomach Neoplasms | 1983 |
Transforming activities of methotrexate, hydroxyurea and 5-fluorouracil in different cell systems.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Dose-Response Relationship, Drug; Ectromelia virus; Fluorouracil; Hydroxyurea; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA | 1983 |
The cause of neural tube defects: some experiments and a hypothesis.
Topics: Animals; Disease Models, Animal; DNA; Female; Fluorouracil; Gestational Age; Hydroxyurea; Mice; Mice, Mutant Strains; Mitomycins; Neural Tube Defects; Pregnancy | 1983 |
Formation of UV-induced apoptosis relates to the cell cycle.
Topics: Animals; Cell Count; Cell Cycle; Cell Division; Cell Survival; Colchicine; Fluorouracil; Guinea Pigs; Hydroxyurea; Methotrexate; Skin; Sunburn; Ultraviolet Rays | 1982 |
Chemotherapy of hormone-resistant stage D prostatic cancer.
Topics: Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Estramustine; Fluorouracil; Humans; Hydroxyurea; Lomustine; Male; Melphalan; Methotrexate; Prednimustine; Prostatic Neoplasms | 1980 |
Volume increase in L5222 leukemic cells following chemotherapy: manifestation of leukemic cell damage.
Topics: Animals; Ascitic Fluid; Cytarabine; Daunorubicin; Fluorouracil; Hydroxyurea; Leukemia, Experimental; Rats; Vincristine | 1981 |
Characterization of a developmentally early macrophage progenitor found in normal mouse marrow.
Topics: Animals; Cell Division; Cells, Cultured; Fluorouracil; Granulocytes; Hematopoietic Stem Cells; Hydroxyurea; Macrophages; Mice | 1981 |
The in vivo incorporation of triated thymidine into liver cell nuclear DNA in mice treated chronically with carbon tetrachloride or with diethylnitrosamine.
Topics: Animals; Bromodeoxyuridine; Carbon Tetrachloride Poisoning; Cell Nucleus; Diethylnitrosamine; DNA; DNA Repair; Fluorouracil; Hydroxyurea; Liver; Mice; Nitrosamines; Thymidine | 1980 |
Engraftment of bone marrow cells into normal unprepared hosts: effects of 5-fluorouracil and cell cycle status.
Topics: Animals; Bone Marrow Transplantation; Cell Cycle; Female; Fluorouracil; Hydroxyurea; Male; Mice; Mice, Inbred BALB C | 1995 |
Intensive multimodality therapy for carcinoma of the esophagus and gastroesophageal junction.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Esophageal Neoplasms; Esophagogastric Junction; Female; Fluorouracil; Follow-Up Studies; Humans; Hydroxyurea; Leucovorin; Male; Middle Aged; Neoplasm Staging; Postoperative Care; Radiotherapy, Adjuvant; Remission Induction; Survival Rate | 1995 |
Impact of different fluorouracil biochemical modulators on cellular dihydropyrimidine dehydrogenase.
Topics: Allopurinol; Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Division; Cisplatin; Dihydrouracil Dehydrogenase (NADP); Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Oxidoreductases; Pancreatic Neoplasms; Platelet Aggregation Inhibitors; Tumor Cells, Cultured | 1996 |
Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell death.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-X Protein; Clone Cells; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Gamma Rays; Genes, bcl-2; Humans; Hydroxyurea; Methotrexate; Mice; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; S Phase; Teniposide; Transfection; Vincristine | 1997 |
Interferon induces thymidine phosphorylase/platelet-derived endothelial cell growth factor expression in vivo.
Topics: Antineoplastic Agents; Blood Platelets; Clinical Trials as Topic; Colonic Neoplasms; Endothelial Growth Factors; Enzyme Induction; Fluorouracil; Humans; Hydroxyurea; Interferon alpha-2; Interferon beta-1a; Interferon beta-1b; Interferon-alpha; Interferon-beta; Leukocytes, Mononuclear; Neoplasms; Recombinant Proteins; RNA, Messenger; Thymidine Phosphorylase; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
[How toxic and effective is simultaneous radiochemotherapy with hydroxyurea, 5-FU and cisplatin in cervix carcinoma?].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenosquamous; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Hydroxyurea; Radiotherapy Dosage; Uterine Cervical Neoplasms | 1998 |
Concomitant chemotherapy and reirradiation as management for recurrent cancer of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy Dosage; Retrospective Studies; Survival Analysis; Treatment Outcome | 1999 |
Effects of perturbations of pools of deoxyribonucleoside triphosphates on expression of ribonucleotide reductase, a G1/S transition state enzyme, in p53-mutated cells.
Topics: Cell Cycle; Cell Division; Colonic Neoplasms; Deoxyribonucleotides; Fluorouracil; G1 Phase; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Macromolecular Substances; Mutation; Recombinant Proteins; Ribonucleotide Reductases; RNA, Messenger; S Phase; Transcription, Genetic; Tumor Cells, Cultured | 1998 |
Time to add chemotherapy to radiotherapy for cervical cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Cisplatin; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Female; Fluorouracil; Humans; Hydroxyurea; Hysterectomy; Radiotherapy Dosage; Research Design; Survival Rate; Uterine Cervical Neoplasms | 1999 |
Chemotherapy plus radiation improves survival in patients with cervical cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Hydroxyurea; Randomized Controlled Trials as Topic; Uterine Cervical Neoplasms | 1999 |
Antagonistic interplay between antimitotic and G1-S arresting agents observed in experimental combination therapy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Drug Administration Schedule; Fluorouracil; G1 Phase; Humans; Hydroxyurea; KB Cells; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; S Phase; Tumor Cells, Cultured | 1999 |
Antisense suppression of proline-directed protein kinase FA enhances chemosensitivity in human prostate cancer cells.
Topics: Antineoplastic Agents; Carboplatin; Cell Survival; Cisplatin; DNA, Antisense; DNA, Complementary; DNA, Recombinant; Dose-Response Relationship, Drug; Fluorouracil; Gene Expression Regulation, Enzymologic; Genetic Vectors; Humans; Hydroxyurea; Male; Paclitaxel; Proline-Directed Protein Kinases; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Transfection; Tumor Cells, Cultured | 2000 |
Recurrent head and neck cancer: retreatment of previously irradiated areas with combined chemotherapy and radiation therapy-results of a prospective study.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dermatitis; Drug Eruptions; Feasibility Studies; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Jugular Veins; Linear Models; Male; Middle Aged; Mucous Membrane; Neoplasm Recurrence, Local; Prospective Studies; Radiotherapy Dosage; Remission Induction; Retreatment; Stroke; Survival Rate; Trismus; Venous Thrombosis | 2000 |
Chemoradiotherapy: the new standard care for invasive cervical cancer.
Topics: Antineoplastic Agents; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Hydroxyurea; Neoadjuvant Therapy; Randomized Controlled Trials as Topic; Survival Analysis; Uterine Cervical Neoplasms | 2000 |
Beyond hydroxyurea.
Topics: Animals; Antiviral Agents; Benzamidines; Dipyridamole; Disease Models, Animal; Floxuridine; Fluorouracil; Humans; Hydroxamic Acids; Hydroxyurea; Mice; Murine Acquired Immunodeficiency Syndrome; Ribonucleotide Reductases | 1995 |
Influence of timing of administration of 5-fluorouracil to donors on bone marrow engraftment in nonmyeloablated hosts.
Topics: Animals; Blotting, Southern; Bone Marrow Cells; Bone Marrow Transplantation; Cell Cycle; Colony-Forming Units Assay; DNA Replication; Drug Administration Schedule; Female; Fluorouracil; Graft Survival; Hematopoietic Stem Cells; Hydroxyurea; Male; Mice | 2001 |
[Influence of chemotherapeutants and cytokines on growth and transgene expression of bone marrow cells from MT/p210(bcr-abl) transgenic mice].
Topics: Animals; Antigens, Polyomavirus Transforming; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Female; Fluorouracil; Fusion Proteins, bcr-abl; Gene Expression; Hydroxyurea; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; RNA, Messenger; Stem Cell Factor | 1999 |
Enhancement of DNA ligase I level by gemcitabine in human cancer cells.
Topics: Antimetabolites, Antineoplastic; Blotting, Western; Cell Cycle; Cytarabine; Deoxycytidine; DNA Ligase ATP; DNA Ligases; Dose-Response Relationship, Drug; Enzyme Activation; Fluorouracil; Gemcitabine; Humans; Hydroxyurea; Tumor Cells, Cultured | 2002 |
Weekly carboplatin and paclitaxel followed by concomitant paclitaxel, fluorouracil, and hydroxyurea chemoradiotherapy: curative and organ-preserving therapy for advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Combined Modality Therapy; Disease Progression; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Lymph Nodes; Male; Middle Aged; Paclitaxel; Quality of Life; Radiotherapy Dosage; Remission Induction; Survival Rate; Treatment Outcome | 2003 |
Prognostic factor analysis in advanced gastric cancer patients treated with hydroxyurea, leucovorin, 5-fluorouracil, and cisplatin (HLFP regimen).
Topics: Adenocarcinoma; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoembryonic Antigen; Cisplatin; Disease-Free Survival; Drug Evaluation; Female; Fluorouracil; Gastrointestinal Diseases; Hematologic Diseases; Humans; Hydroxyurea; Karnofsky Performance Status; Kidney Diseases; Leucovorin; Life Tables; Liver Neoplasms; Male; Middle Aged; Nervous System Diseases; Prognosis; Proportional Hazards Models; Quality of Life; Risk Factors; Stomach Neoplasms; Survival Analysis; Treatment Outcome; Weight Gain | 2003 |
Induction chemotherapy followed by concomitant TFHX chemoradiotherapy with reduced dose radiation in advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cohort Studies; Combined Modality Therapy; Disease Progression; Disease-Free Survival; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Paclitaxel; Quality of Life; Radiotherapy Dosage; Remission Induction; Survival Rate | 2003 |
With regard to "Induction chemotherapy followed by concomitant chemoradiotherapy in the treatment of locoregionally advanced nasopharyngeal cancer" by Oh et al. (AnnOnc 2003; 14: 464-569).
Topics: Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Disease-Free Survival; Fluorouracil; Humans; Hydroxyurea; Interferon-alpha; Leucovorin; Nasopharyngeal Neoplasms; Sample Size; Time Factors | 2004 |
Overproduction of thymidine by recombinant brevibacterium helvolum amplified with thymidine monophosphate phosphohydrolase gene from bacteriophage PBS2.
Topics: Bacterial Proteins; Bacteriophages; Brevibacterium; Chromatography, High Pressure Liquid; Cloning, Molecular; Drug Resistance, Bacterial; Fermentation; Fluorouracil; Hydroxyurea; Mutation; Nucleotidases; Phosphoric Monoester Hydrolases; Plasmids; Recombinant Proteins; Thymidine; Thymidine Monophosphate; Trimethoprim | 2004 |
Outcome of surgery for oesophageal carcinoma in a low volume centre, with and without preoperative chemoradiotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Cisplatin; Combined Modality Therapy; Esophageal Neoplasms; Female; Fluorouracil; Hospital Mortality; Humans; Hydroxyurea; Male; Neoplasm Staging; Prospective Studies; Survival Analysis; Treatment Outcome | 2004 |
Patterns of failure, prognostic factors and survival in locoregionally advanced head and neck cancer treated with concomitant chemoradiotherapy: a 9-year, 337-patient, multi-institutional experience.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Disease-Free Survival; Dose Fractionation, Radiation; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Metastasis; Prognosis; Prospective Studies | 2004 |
5-fluorouracil and hydroxyurea enhance adenovirus-mediated transgene expression in colon and hepatocellular carcinoma cells.
Topics: Adenoviridae; Antimetabolites, Antineoplastic; Antineoplastic Agents; beta-Galactosidase; Carcinoma, Hepatocellular; Cell Line, Tumor; Colonic Neoplasms; DNA, Viral; Dose-Response Relationship, Drug; Fluorouracil; Gene Expression Regulation, Neoplastic; Genetic Vectors; Humans; Hydroxyurea; Liver Neoplasms; Microscopy, Confocal; Polymerase Chain Reaction; Time Factors; Transgenes | 2005 |
Preoperative sequential chemotherapy in locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cohort Studies; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Remission Induction | 2005 |
Long-term outcome of concurrent chemotherapy and reirradiation for recurrent and second primary head-and-neck squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Camptothecin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Hydroxyurea; Irinotecan; Male; Mandibular Diseases; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Osteoradionecrosis; Paclitaxel; Prognosis; Radiotherapy Dosage; Treatment Failure; Treatment Outcome | 2006 |
Functional organ preservation with definitive chemoradiotherapy for T4 laryngeal squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Hydroxyurea; Immunohistochemistry; Kaplan-Meier Estimate; Laryngeal Neoplasms; Male; Middle Aged; Neoplasm Staging; Organ Preservation; Paclitaxel; Probability; Quality of Life; Radiotherapy Dosage; Retrospective Studies; Risk Assessment; Survival Analysis; Treatment Outcome | 2008 |
Overexpression of the dual specificity phosphatase, Cdc25C, confers sensitivity on tumor cells to doxorubicin-induced cell death.
Topics: Antibiotics, Antineoplastic; Apoptosis; cdc25 Phosphatases; Cell Cycle; Cell Death; Cell Line, Tumor; Doxorubicin; Dual-Specificity Phosphatases; Fluorouracil; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Hydroxyurea; Phosphorylation; RNA, Small Interfering | 2008 |
Chemoradiotherapy for locoregionally advanced squamous cell carcinoma of the base of tongue.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Irinotecan; Leucovorin; Male; Middle Aged; Neck Dissection; Paclitaxel; Radiotherapy Dosage; Radiotherapy, Adjuvant; Radiotherapy, Intensity-Modulated; Recombinant Proteins; Tongue Neoplasms | 2010 |
The human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage.
Topics: Antineoplastic Agents; Bone Neoplasms; Bromodeoxyuridine; Camptothecin; Cell Growth Processes; Cell Line, Tumor; Cisplatin; DNA Damage; Exodeoxyribonucleases; Fibroblasts; Fluorouracil; Histones; Humans; Hydroxyurea; Osteosarcoma; RecQ Helicases; Werner Syndrome Helicase | 2010 |
Outcome of stage IVA cervical cancer patients with disease limited to the pelvis in the era of chemoradiation: a Gynecologic Oncology Group study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Humans; Hydroxyurea; Middle Aged; Misonidazole; Neoplasm Staging; Randomized Controlled Trials as Topic; Retrospective Studies; Survival Rate; Treatment Outcome; Uterine Cervical Neoplasms | 2011 |
Concurrent chemotherapy and intensity-modulated radiotherapy for organ preservation of locoregionally advanced oral cavity cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Hydroxyurea; Male; Middle Aged; Mouth; Mouth Neoplasms; Organ Preservation; Quality of Life; Radiotherapy, Intensity-Modulated; Survival Rate; Treatment Outcome | 2011 |
Prior chemoradiotherapy adversely impacts outcomes of recurrent and second primary head and neck cancer treated with concurrent chemotherapy and reirradiation.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Dose Fractionation, Radiation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Prognosis; Radiotherapy Dosage; Retreatment; Retrospective Studies; Risk Factors; Smoking; Treatment Outcome | 2011 |
Adjuvant chemoradiotherapy for locoregionally advanced and high-risk salivary gland malignancies.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Female; Fluorouracil; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Salivary Gland Neoplasms; Treatment Outcome | 2011 |
Mcm2 phosphorylation and the response to replicative stress.
Topics: Alleles; Amino Acid Transport Systems, Basic; Caffeine; Cell Cycle Proteins; Checkpoint Kinase 2; Chromosomal Proteins, Non-Histone; DNA Damage; DNA Replication; Enzyme Inhibitors; Fluorouracil; Gene Deletion; Hydroxyurea; Mutation; Oxidative Stress; Phosphorylation; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2012 |
DNA synthesis as a therapeutic target: the first 65 years.
Topics: Aminopterin; Antimetabolites, Antineoplastic; DNA Replication; Fluorouracil; Folic Acid; Folic Acid Antagonists; History, 20th Century; Humans; Hydroxyurea; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrahydrofolate Dehydrogenase | 2012 |
Outcomes of induction chemotherapy followed by concurrent chemoradiation for nasopharyngeal carcinoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemoradiotherapy; Chemotherapy, Adjuvant; Child; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Hydroxyurea; Induction Chemotherapy; Male; Middle Aged; Nasopharyngeal Neoplasms; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Platinum; Radiotherapy Dosage; Remission Induction; Survival Rate; Treatment Outcome; Young Adult | 2013 |
Interference in DNA replication can cause mitotic chromosomal breakage unassociated with double-strand breaks.
Topics: Animals; Antigens, Nuclear; Aphidicolin; Apoptosis; Cell Line, Tumor; Chickens; Chromosome Breakage; DNA Breaks, Double-Stranded; DNA Helicases; DNA Repair; DNA Repair Enzymes; DNA Replication; DNA-Binding Proteins; Fluorouracil; Gene Knockout Techniques; Humans; Hydroxyurea; Ku Autoantigen; Mitosis | 2013 |
Locally advanced adenocarcinoma and adenosquamous carcinomas of the cervix compared to squamous cell carcinomas of the cervix in gynecologic oncology group trials of cisplatin-based chemoradiation.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenosquamous; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Erythropoietin; Female; Fluorouracil; Humans; Hydroxyurea; Middle Aged; Multivariate Analysis; Neoplasm Staging; Prognosis; Proportional Hazards Models; Radiotherapy; Recombinant Proteins; Retrospective Studies; Treatment Outcome; Tumor Burden; Uterine Cervical Neoplasms | 2014 |
Establishment of a rapid drug screening system based on embryonic stem cells.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Cytarabine; Dexamethasone; DNA Fragmentation; Drug Evaluation, Preclinical; Embryonic Stem Cells; Fluorouracil; Hydroxyurea; Indomethacin; Mice | 2015 |
Age most significant predictor of requiring enteral feeding in head-and-neck cancer patients.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; Docetaxel; Enteral Nutrition; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm Staging; Prognosis; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated; Retrospective Studies; Taxoids | 2015 |
Survival prognostic factors for metachronous second primary head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Deoxycytidine; Docetaxel; Female; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neoplasms, Second Primary; Paclitaxel; Prognosis; Squamous Cell Carcinoma of Head and Neck; Survival Analysis; Taxoids; Treatment Outcome; Young Adult | 2017 |
Assessment of neurotoxicity of pharmacological compounds during early neural development of human embryonic stem cells.
Topics: Animals; Ascorbic Acid; Cell Differentiation; Cell Survival; Cells, Cultured; Cytarabine; Dexamethasone; Fluorouracil; Human Embryonic Stem Cells; Humans; Hydroxyurea; Indomethacin; Nestin; Neurogenesis | 2017 |
An In Silico Study of the Antioxidant Ability for Two Caffeine Analogs Using Molecular Docking and Quantum Chemical Methods.
Topics: Antioxidants; Caffeine; Catalytic Domain; Computer Simulation; Enzymes; Febuxostat; Fluorouracil; Hydroxyurea; Molecular Docking Simulation; Quantum Theory | 2018 |
Mechanism of acquired 5FU resistance and strategy for overcoming 5FU resistance focusing on 5FU metabolism in colon cancer cell lines.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Metabolic Networks and Pathways; Pyrrolidines; Ribonucleotide Reductases; Thymidine Phosphorylase; Thymine; Trifluridine | 2021 |
Unraveling the Mechanisms of Clinical Drugs-Induced Neural Tube Defects Based on Network Pharmacology and Molecular Docking Analysis.
Topics: Animals; Anticonvulsants; Antineoplastic Agents; Class I Phosphatidylinositol 3-Kinases; ErbB Receptors; Female; Fluorouracil; Hydroxyurea; Methotrexate; Mice; Molecular Docking Simulation; Network Pharmacology; Neural Tube Defects; Phosphatidylinositol 3-Kinases; Pregnancy; Tretinoin; Valproic Acid | 2022 |