fluorouracil and fenofibrate

fluorouracil has been researched along with fenofibrate in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (31.25)29.6817
2010's9 (56.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Angus, E; Fincher, S; Garg, R1
Clive, S; Michie, CO; Rivans, I; Sakala, M; Strachan, MW1
Harnoss, JM; Kimmer, G; Klose, J; Pavicevic, S; Radhakrishnan, P; Ritter, AS; Scheer, J; Schmidt, T; Schneider, M; Strowitzki, MJ; Tuffs, C; Volz, C; Vondran, F1
Abdelzaher, WY; Bayoumi, AMA; El-Tahawy, NFG; Refaie, MMM; Shehata, S1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Adachi, M; Hareyama, M; Imai, K; Shinomura, Y; Zhang, Y; Zou, H1

Reviews

2 review(s) available for fluorouracil and fenofibrate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Capecitabine-induced severe hypertriglyceridaemia and diabetes: a case report and review of the literature.
    Diabetic medicine : a journal of the British Diabetic Association, 2009, Volume: 26, Issue:12

    Topics: Antimetabolites, Antineoplastic; Blood Glucose; Capecitabine; Colonic Neoplasms; Deoxycytidine; Fenofibrate; Fluorouracil; Glycated Hemoglobin; Humans; Hypertriglyceridemia; Hypolipidemic Agents; Lipids; Male; Middle Aged; Treatment Outcome

2009

Other Studies

14 other study(ies) available for fluorouracil and fenofibrate

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
The frequency and severity of capecitabine-induced hypertriglyceridaemia in routine clinical practice: a prospective study.
    British journal of cancer, 2010, Aug-24, Volume: 103, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Diabetes Mellitus; Dyslipidemias; Fenofibrate; Fluorouracil; Humans; Hypertriglyceridemia; Middle Aged; Prospective Studies; Risk

2010
High hepatic expression of PDK4 improves survival upon multimodal treatment of colorectal liver metastases.
    British journal of cancer, 2019, Volume: 120, Issue:7

    Topics: Aged; Animals; Antineoplastic Agents; Colorectal Neoplasms; Combined Modality Therapy; Down-Regulation; Female; Fenofibrate; Fluorouracil; Gene Knock-In Techniques; Gene Knockdown Techniques; Hep G2 Cells; Hepatectomy; Hepatocytes; Humans; In Vitro Techniques; Liver; Liver Neoplasms; Male; Metastasectomy; Mice; Middle Aged; Neoadjuvant Therapy; Oxaliplatin; Prognosis; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; RNA, Messenger; Survival Rate; Up-Regulation

2019
The IL-6/STAT Signaling Pathway and PPARα Are Involved in Mediating the Dose-Dependent Cardioprotective Effects of Fenofibrate in 5-Fluorouracil-Induced Cardiotoxicity.
    Cardiovascular drugs and therapy, 2022, Volume: 36, Issue:5

    Topics: Antioxidants; Cardiotoxicity; Caspase 3; Fenofibrate; Fluorouracil; Glutathione; Humans; Interleukin-6; Malondialdehyde; Oxidative Stress; PPAR alpha; Signal Transduction; STAT4 Transcription Factor

2022
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Histone deacetylase inhibitors enhance phosphorylation of histone H2AX after ionizing radiation.
    International journal of radiation oncology, biology, physics, 2006, Jul-01, Volume: 65, Issue:3

    Topics: Animals; Cell Cycle Proteins; Cell Line, Tumor; Cinnamates; Depsipeptides; DNA; DNA Damage; Enzyme Inhibitors; Fluorouracil; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histones; Humans; Mice; Mice, Nude; Naphthalenes; p300-CBP Transcription Factors; Phosphorylation; Pyrones; Radiation-Sensitizing Agents; Transcription Factors

2006