fluorouracil has been researched along with epidermal growth factor in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (10.26) | 18.7374 |
| 1990's | 6 (15.38) | 18.2507 |
| 2000's | 13 (33.33) | 29.6817 |
| 2010's | 14 (35.90) | 24.3611 |
| 2020's | 2 (5.13) | 2.80 |
| Authors | Studies |
|---|---|
| Costa, JW; Evitts, SM; Lindquist, LE; Nicolson, M; Sonis, ST | 1 |
| Amagase, H; Fuwa, T; Hashimoto, K; Kakimoto, M; Tsukagoshi, S | 1 |
| Ohkura, H; Okazaki, N; Saito, D; Yoshida, S | 1 |
| Joyce, NC; Matkin, ED; Neufeld, AH | 1 |
| Bartels, SP; Jumblatt, MM; Neufeld, AH; Raymond, GM | 1 |
| Counts, RS; Nowak, G; Schnellmann, RG; Wyatt, RD | 1 |
| Aizawa, K; Katayanagi, N; Muto, I; Muto, T; Suzuki, S; Suzuki, T; Tanaka, N; Tanaka, O; Tanaka, S; Yabusaki, H | 1 |
| Kopecky, EA; Rootman, DS | 1 |
| Bianco, AR; Ciardiello, F; De Luca, A; Normanno, N; Pepe, S; Salomon, DS; Sandomenico, C; Selvam, MP | 1 |
| Kitaura, K; Kumagai, K; Kusada, O; Mochizuki, Y; Terai, Y; Ueda, M; Ueki, K; Ueki, M; Yamada, N | 1 |
| Chen, M; Gao, M; Lan, P; Wu, J | 1 |
| Erwin, CR; Huang, FS; Kemp, CJ; Warner, BW; Williams, JL | 1 |
| Ciccolini, J; Dubreuil, A; Etienne, MC; Fischel, JL; Formento, JL; Formento, P; Francoual, M; Magné, N; Milano, G; Renée, N; Tiffon, C | 1 |
| Kanazawa, J; Kashima, N; Ueda, M | 1 |
| El-Salhy, M; Tjomsland, V | 1 |
| El-Salhy, M; Hilding, L; Royson, H; Tjomsland, V | 1 |
| Benson, AB; Mulcahy, MF; Wisinski, KB | 1 |
| Chu, E; Lee, JJ | 1 |
| Bueter, M; Fein, M; Gasser, M; Illert, B; Meyer, D; Reimer, P; Thalheimer, A; Thiede, A; Waaga-Gasser, AM | 1 |
| Ducreux, M; Laurent-Puig, P; Lièvre, A; Loriot, MA | 1 |
| Muslimov, GF | 1 |
| Tao, KX; Wang, GB; Ye, L | 1 |
| Alonso-Varona, A; Caramés, M; García-Alonso, I; Palomares, T | 2 |
| Andersen, RF; Jakobsen, A; Jensen, LH; Ploen, J; Spindler, KG | 1 |
| Guan, K; Guo, S; Li, C; Ma, W; Wang, D; Zhang, S; Zhang, Y; Zhong, Y; Zhou, C | 1 |
| Ahmad, R; Beauchamp, RD; Chaturvedi, R; Chen, X; Dhawan, P; Eschrich, S; Harris, RC; Krishnan, M; Midha, R; Mittal, MK; Singh, AB; Smith, JJ; Washington, MK; Wilson, KT; Yeatman, TJ | 1 |
| Chefrour, M; Ciccolini, J; Denden, A; Fischel, JL; Formento, P; Giacometti, S; Iliadis, A; Milano, G; Renée, N | 1 |
| Bennouna, J; Chatelut, E; Douillard, JY; El Hannani, C; Etienne-Grimaldi, MC; Faroux, R; Formento, JL; Francois, E; Francoual, M; Hennebelle, I; Jacob, JH; Milano, G | 1 |
| Berk, V; Elmalı, F; Er, O; Inanç, M; Karaca, H; Ozkan, M; Saraymen, R | 1 |
| Campanella, G; Clemente, C; D'Attoma, B; Giotta, F; Linsalata, M; Orlando, A; Riezzo, G; Russo, F | 1 |
| Chen, L; Duan, W; He, L; Kong, L; She, X; Shigdar, S; Wang, T | 1 |
| Arai, J; Matsumoto, K; Miyazaki, T; Mochinaga, K; Nagasaki, T; Nagayasu, T; Nanashima, A; Tominaga, T; Tsuchiya, T; Tsukamoto, K; Yamasaki, N | 1 |
| Clarke, DT; Florin, TH; Hasnain, SZ; He, Y; Hooper, JD; Lourie, R; Lumley, JW; McGuckin, MA; McMillan, NA; Oancea, I; Sheng, YH; Sutton, P; Tong, H; Wang, R; Wong, KY | 1 |
| Brünner, N; Christensen, IJ; Glimelius, B; Guren, TK; Ikdahl, T; Kure, EH; Moreira, JM; Nielsen, HJ; Noer, J; Nordgaard, C; Pfeiffer, P; Sorbye, H; Tarpgaard, LS; Tveit, KM; Ørum-Madsen, MS | 1 |
| Chao, NJ; Chen, BJ; Chute, JP; Doan, PL; Hsu, DS; Kam, AYF; Kliassov, EG; Piryani, SO; Spector, NL | 1 |
| Britton, J; Dua, HS; Ghoz, N; Hogan, E; Mohammed, I; Ross, AR; Said, DG | 1 |
| Bao, J; Wu, P; Zhou, Q; Zhu, H; Zhuang, Y | 1 |
| Afzal, O; Akhter, MH; Al-Abbasi, FA; Alharbi, KS; Almalki, WH; Alrobaian, M; Altamimi, ASA; Altowayan, WM; Beg, S; Gupta, M; Kazmi, I; Li, S; Rahman, M; Singh, T; Xu, Z | 1 |
2 review(s) available for fluorouracil and epidermal growth factor
| Article | Year |
|---|---|
Update on clinical data combining capecitabine with targeted agents in newly diagnosed colorectal cancer.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Colorectal Neoplasms; Deoxycytidine; Epidermal Growth Factor; ErbB Receptors; Fluorouracil; Humans; Irinotecan; Leucovorin; Organoplatinum Compounds; Oxaliplatin; Vascular Endothelial Growth Factor A | 2007 |
[Antibody treatment in colorectal cancer--what the surgeon needs to know].
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bevacizumab; Camptothecin; Cetuximab; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Drug Therapy, Combination; Epidermal Growth Factor; ErbB Receptors; Fluorouracil; Humans; Irinotecan; Leucovorin; Neoplasm Metastasis; Panitumumab; Phthalazines; Pyridines; Randomized Controlled Trials as Topic; Vascular Endothelial Growth Factor A; Vitamin B Complex | 2008 |
3 trial(s) available for fluorouracil and epidermal growth factor
| Article | Year |
|---|---|
Multifactorial pharmacogenetic analysis in colorectal cancer patients receiving 5-fluorouracil-based therapy together with cetuximab-irinotecan.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; Epidermal Growth Factor; ErbB Receptors; Female; Fluorouracil; Humans; Irinotecan; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Prospective Studies; Thymidylate Synthase | 2012 |
The effects of fluorouracil, epirubicin, and cyclophosphamide (FEC60) on the intestinal barrier function and gut peptides in breast cancer patients: an observational study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Cholera Toxin; Cyclophosphamide; Diarrhea; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; Epirubicin; Female; Fluorouracil; Ghrelin; Glucagon-Like Peptide 2; Haptoglobins; Humans; Intestinal Absorption; Intestinal Mucosa; Italy; Lactulose; Mannitol; Middle Aged; Peptides; Permeability; Prospective Studies; Protein Precursors; Stomatitis; Time Factors; Treatment Outcome | 2013 |
TIMP-1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRAS-mutated colorectal cancer cells: a potential novel approach to the treatment of metastatic colorectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cetuximab; Colorectal Neoplasms; Epidermal Growth Factor; Female; Fluorouracil; Humans; Male; Mutation; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Phenotype; Proto-Oncogene Proteins p21(ras); Signal Transduction; Survival Analysis; Tissue Inhibitor of Metalloproteinase-1 | 2016 |
34 other study(ies) available for fluorouracil and epidermal growth factor
| Article | Year |
|---|---|
Effect of epidermal growth factor on ulcerative mucositis in hamsters that receive cancer chemotherapy.
Topics: Animals; Cell Division; Cricetinae; Epidermal Growth Factor; Epithelial Cells; Epithelium; Fluorouracil; Infusion Pumps, Implantable; Male; Mesocricetus; Mouth Mucosa; Stomatitis; Time Factors; Ulcer | 1992 |
Epidermal growth factor receptor-mediated selective cytotoxicity of antitumor agents toward human xenografts and murine syngeneic solid tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Fluorouracil; Humans; Lethal Dose 50; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Time Factors | 1989 |
[Effect of human epidermal factor (hEGF) on antitumor activity of 5-fluorouracil (5-FU) in human gastric cancer cell lines].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Cell Division; Cell Line; Cell Survival; Drug Screening Assays, Antitumor; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Fluorouracil; Humans; Stomach Neoplasms; Tumor Cells, Cultured | 1989 |
Corneal endothelial wound closure in vitro. Effects of EGF and/or indomethacin.
Topics: Animals; Cell Count; Cell Division; Cell Movement; Cells, Cultured; Disease Models, Animal; Endothelium, Corneal; Epidermal Growth Factor; Fixatives; Fluorouracil; Indomethacin; Male; Microscopy, Electron, Scanning; Rabbits; Time Factors; Wound Healing | 1989 |
Rabbit corneal endothelial cells in vitro: effects of EGF.
Topics: Animals; Cell Count; Cell Movement; Cells, Cultured; Cornea; Endothelium; Epidermal Growth Factor; Fluorouracil; Mitosis; Models, Biological; Rabbits; Wound Healing | 1986 |
Nephrotoxicant inhibition of renal proximal tubule cell regeneration.
Topics: Animals; Cell Division; Cell Movement; Epidermal Growth Factor; Female; Fluorouracil; Kidney Tubules, Proximal; Nephrons; Physical Stimulation; Rabbits; Regeneration; Toxins, Biological; Transforming Growth Factor beta | 1995 |
Augmentation of 5-fluorouracil cytotoxicity by epidermal growth factor in a newly established human signet-ring cell carcinoma of the stomach in culture.
Topics: Carcinoma, Signet Ring Cell; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Epidermal Growth Factor; Female; Flow Cytometry; Fluorouracil; Humans; Lymphatic Metastasis; Middle Aged; Stomach Neoplasms; Tumor Cells, Cultured | 1994 |
Antimetabolite interactions with epidermal growth factor.
Topics: Administration, Topical; Animals; Antimetabolites; Chemotherapy, Adjuvant; Cornea; Corneal Stroma; Drug Interactions; Epidermal Growth Factor; Epithelium; Fluorouracil; Injections; Mitomycin; Ophthalmic Solutions; Perfusion; Rabbits; Recombinant Proteins; Wound Healing | 1996 |
Anti-sense oligonucleotides directed against EGF-related growth factors enhance anti-proliferative effect of conventional anti-tumor drugs in human colon-cancer cells.
Topics: Amphiregulin; Antineoplastic Agents; Cell Division; Cisplatin; Colonic Neoplasms; DNA, Neoplasm; Doxorubicin; Drug Combinations; Drug Synergism; EGF Family of Proteins; Epidermal Growth Factor; Flow Cytometry; Fluorouracil; Glycoproteins; GPI-Linked Proteins; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Membrane Glycoproteins; Mitomycin; Neoplasm Proteins; Oligonucleotides, Antisense; RNA, Messenger; Thionucleotides; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1997 |
Regulation of dihydropyrimidine dehydrogenase and pyrimidine nucleoside phosphorylase activities by growth factors and subsequent effects on 5-fluorouracil sensitivity in tumor cells.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cell Division; Dihydrouracil Dehydrogenase (NADP); Drug Synergism; Epidermal Growth Factor; Female; Fluorouracil; Humans; Oxidoreductases; Pentosyltransferases; Pyrimidine Phosphorylases; Transforming Growth Factor alpha; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2000 |
[Effects of epidermal growth factor, basic fibroblast growth factor and 5-fluorouracil on human retinal pigment epithelial wound closure in vitro].
Topics: Cell Division; Cell Movement; Cells, Cultured; Epidermal Growth Factor; Fibroblast Growth Factor 2; Fluorouracil; Humans; Pigment Epithelium of Eye; Wound Healing | 1999 |
Role of epidermal growth factor and its receptor in chemotherapy-induced intestinal injury.
Topics: Animals; Antineoplastic Agents; Enteritis; Epidermal Growth Factor; ErbB Receptors; Fluorouracil; Gene Expression; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Transgenic; Microvilli; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor alpha | 2002 |
Molecular mechanisms underlying the interaction between ZD1839 ('Iressa') and cisplatin/5-fluorouracil.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cisplatin; DNA Repair; Drug Interactions; Epidermal Growth Factor; ErbB Receptors; Fluorouracil; Gefitinib; Head and Neck Neoplasms; Humans; Protein-Tyrosine Kinases; Quinazolines; Signal Transduction; Tumor Cells, Cultured | 2003 |
Effect of 5-fluorouracil and epidermal growth factor on cell growth and dihydropyrimidine dehydrogenase regulation in human uterine cervical carcinoma SKG-IIIb cells.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cell Division; Dihydrouracil Dehydrogenase (NADP); DNA Primers; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Epidermal Growth Factor; Female; Fluorouracil; Humans; Immunoblotting; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2003 |
Anti-tumour effects of triple therapy with octreotide, galanin and serotonin in comparison with those of 5-fluorouracil/leukovorin on human colon cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Body Weight; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Epidermal Growth Factor; Fluorouracil; Galanin; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Leucovorin; Mice; Mice, Nude; Neovascularization, Pathologic; Octreotide; Platelet Endothelial Cell Adhesion Molecule-1; Poly(ADP-ribose) Polymerases; Serotonin; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2005 |
Comparison between triple therapy with octreotide, galanin and serotonin vs. irinotecan or oxaliplatin in combination with 5-fluorouracil/leukovorin in human colon cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Body Weight; Camptothecin; Cell Proliferation; Colonic Neoplasms; Epidermal Growth Factor; Female; Fluorouracil; Galanin; Immunohistochemistry; In Situ Nick-End Labeling; Irinotecan; Leucovorin; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Octreotide; Organoplatinum Compounds; Oxaliplatin; Platelet Endothelial Cell Adhesion Molecule-1; Poly(ADP-ribose) Polymerases; Serotonin; Time Factors; Treatment Outcome; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2005 |
Panitumumab in metastatic colorectal cancer.
Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Epidermal Growth Factor; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Panitumumab | 2007 |
[The biological point of view on pharmacogenetics of anticancer agents in colorectal cancer].
Topics: Antineoplastic Agents; Camptothecin; Colorectal Neoplasms; Cyclin D1; Dihydrouracil Dehydrogenase (NADP); Epidermal Growth Factor; Fluorouracil; Glucuronosyltransferase; Glutathione Transferase; Humans; Irinotecan; Mutation; Organoplatinum Compounds; Polymorphism, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Receptors, IgG; Thymidylate Synthase | 2008 |
Role of epidermal growth factor gene in the development of pancreatic cancer and efficiency of inhibitors of this gene in the treatment of pancreatic carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Cell Proliferation; Drug Evaluation, Preclinical; Epidermal Growth Factor; ErbB Receptors; Fluorouracil; Gene Frequency; Genetic Predisposition to Disease; Humans; Pancreatic Neoplasms; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Quinazolines; Time Factors; Tumor Cells, Cultured; Tyrphostins | 2008 |
[Synergistic use of epidermal growth factor and 5-fluorouracil for the treatment of human colorectal cancer in BALB/C nude mice subcutaneous xenograft model].
Topics: Animals; Caco-2 Cells; Cell Line, Tumor; Colorectal Neoplasms; Epidermal Growth Factor; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Xenograft Model Antitumor Assays | 2009 |
Glutathione modulation reverses the growth-promoting effect of growth factors, improving the 5-fluorouracil antitumour response in WiDr colon cancer cells.
Topics: Buthionine Sulfoximine; Cell Growth Processes; Cell Line, Tumor; Colonic Neoplasms; Epidermal Growth Factor; Fluorouracil; Glutathione; Hepatocyte Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Pyrrolidonecarboxylic Acid; Thiazolidines; Vascular Endothelial Growth Factor A | 2009 |
EGF61A>G polymorphism as predictive marker of clinical outcome to first-line capecitabine and oxaliplatin in metastatic colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Deoxycytidine; DNA-Binding Proteins; Endonucleases; Epidermal Growth Factor; Feasibility Studies; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Polymorphism, Genetic; Survival Rate; Thymidylate Synthase; Treatment Outcome | 2010 |
Glutathione modulators reverse the pro-tumour effect of growth factors enhancing WiDr cell response to chemotherapeutic agents.
Topics: Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Camptothecin; Cell Growth Processes; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Epidermal Growth Factor; Fluorouracil; Glutathione; Hepatocyte Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Pyrrolidonecarboxylic Acid; Thiazolidines; Vascular Endothelial Growth Factor A | 2010 |
Spheres derived from the human SK-RC-42 renal cell carcinoma cell line are enriched in cancer stem cells.
Topics: Animals; Antigens, CD; Antimetabolites, Antineoplastic; Carcinoma, Renal Cell; Cell Adhesion; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Cell Survival; Endoglin; Epidermal Growth Factor; Fibroblast Growth Factor 2; Flow Cytometry; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Immunophenotyping; Kidney Neoplasms; Mice; Mice, Nude; Neoplasms, Experimental; Neoplastic Stem Cells; Octamer Transcription Factor-3; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; Spheroids, Cellular; Transplantation, Heterologous | 2010 |
Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation.
Topics: Animals; Caco-2 Cells; Cell Division; Claudins; Colonic Neoplasms; Epidermal Growth Factor; ErbB Receptors; Fluorouracil; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Inflammatory Bowel Diseases; Membrane Proteins; Mice; Mice, Nude; Protein Kinases; RNA, Messenger; Transcriptional Activation; Up-Regulation | 2011 |
Positive interaction between lapatinib and capecitabine in human breast cancer models: study of molecular determinants.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Capecitabine; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Female; Fluorouracil; Humans; Lapatinib; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, ErbB-2; Signal Transduction; Thymidine Phosphorylase; Thymidylate Synthase; Xenograft Model Antitumor Assays | 2012 |
Prognostic value of tumor growth factor levels during chemotherapy in patients with metastatic colorectal cancer.
Topics: Angiogenesis Inducing Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Capecitabine; Carcinoma; Colorectal Neoplasms; Deoxycytidine; E-Selectin; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; Female; Fibroblast Growth Factor 2; Fluorouracil; Hepatocyte Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Male; Middle Aged; Oxaloacetates; Platelet-Derived Growth Factor; Prognosis; Vascular Endothelial Growth Factor A | 2012 |
Overcoming acquired drug resistance in colorectal cancer cells by targeted delivery of 5-FU with EGF grafted hollow mesoporous silica nanoparticles.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Drug Carriers; Drug Resistance, Neoplasm; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Flow Cytometry; Fluorouracil; Humans; Lysosomes; Microscopy, Confocal; Nanoparticles; Porosity; Real-Time Polymerase Chain Reaction; S Phase Cell Cycle Checkpoints; Silicon Dioxide; Up-Regulation | 2015 |
Epidermal growth factor signals regulate dihydropyrimidine dehydrogenase expression in EGFR-mutated non-small-cell lung cancer.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Dihydrouracil Dehydrogenase (NADP); Drug Resistance, Neoplasm; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Fluorouracil; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mutation; Plicamycin; Quinazolines; Signal Transduction; Sp1 Transcription Factor | 2016 |
MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target.
Topics: Animals; Antigens, Surface; Antimetabolites, Antineoplastic; Apoptosis; bcl-X Protein; Cell Line, Tumor; Colorectal Neoplasms; Epidermal Growth Factor; Fluorouracil; Heterografts; HT29 Cells; Humans; Membrane Proteins; Mice; Mice, Inbred NOD; Mice, SCID; Mitochondrial Proteins; Molecular Targeted Therapy; NF-kappa B; RNA, Small Interfering; Signal Transduction | 2017 |
Epidermal Growth Factor and Granulocyte Colony Stimulating Factor Signaling Are Synergistic for Hematopoietic Regeneration.
Topics: Animals; Apoptosis; Cell Cycle; Epidermal Growth Factor; ErbB Receptors; Fluorouracil; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cells; Mice; Mice, Inbred C57BL; Signal Transduction | 2018 |
Management of primary pterygium with intra-lesional injection of 5 flurouracil and bevacizumab (Avastin).
Topics: Adult; Aged; Angiogenesis Inhibitors; Antimetabolites; Bevacizumab; Biomarkers; Collagen Type I; Drug Therapy, Combination; Epidermal Growth Factor; Female; Fibroblast Growth Factors; Fluorescent Antibody Technique, Indirect; Fluorouracil; Humans; Injections, Intralesional; Male; Middle Aged; Pterygium; Vascular Endothelial Growth Factor A; Vesicular Transport Proteins; von Willebrand Factor; Young Adult | 2019 |
Enhanced antitumor efficacy in colon cancer using EGF functionalized PLGA nanoparticles loaded with 5-Fluorouracil and perfluorocarbon.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Proliferation; Colonic Neoplasms; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Therapy, Combination; Epidermal Growth Factor; Female; Fluorocarbons; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2020 |
EGF-functionalized lipid-polymer hybrid nanoparticles of 5-fluorouracil and sulforaphane with enhanced bioavailability and anticancer activity against colon carcinoma.
Topics: Biological Availability; Carcinoma; Cell Survival; Colonic Neoplasms; Drug Carriers; Drug Delivery Systems; Epidermal Growth Factor; Fluorouracil; Humans; Lipids; Nanoparticles; Particle Size; Polymers | 2022 |