fluorouracil and eflornithine

fluorouracil has been researched along with eflornithine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19907 (46.67)18.7374
1990's4 (26.67)18.2507
2000's2 (13.33)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Barranco, SC; Ford, PJ; Ho, BY; Koester, SK; Reumont, KJ; Townsend, CM1
Atabek, U; Zirvi, KA1
Carvalho, L; Foulkes, K; Mickey, DD1
Endoh, F; Fujimoto, S; Igarashi, K; Kawata, S; Miyazaki, M; Ohta, M; Shimura, T; Shrestha, RD; Sugasawa, H; Takahashi, O1
Endoh, F; Fujimoto, S; Igarashi, K; Miyazaki, M; Ohta, M; Okui, K; Shrestha, RD; Togawa, Y1
Levin, VA1
Harris, C; Salgo, MP; Tanowitz, HB; Wittner, M1
Gee, E; Ryan, SJ; Wong, CG1
Diekema, KA; Kingsnorth, AN; Malt, RA; McCann, PP; Russell, WE1
Greene, MH1
Hess, KR; Jaeckle, KA; Kyritsis, AP; Levin, VA; Prados, MD; Wong, ET; Yung, WK1
Estensen, RD; Wattenberg, LW; Wiedmann, TS1
Burcharth, J; Pommergaard, HC; Raskov, H; Rosenberg, J1

Reviews

2 review(s) available for fluorouracil and eflornithine

ArticleYear
Chemotherapy of primary brain tumors.
    Neurologic clinics, 1985, Volume: 3, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Eflornithine; Ependymoma; Fluorouracil; Glioblastoma; Humans; Hydroxyurea; Lomustine; Medulloblastoma; Methotrexate; Mitoguazone; Mitolactol; Neoplasm Recurrence, Local; Ornithine; Prednisone; Risk; Thioguanine; Vincristine

1985
The prevention of cutaneous malignant melanoma: high-risk groups, chemoprevention, education, and screening.
    Cancer treatment and research, 1993, Volume: 65

    Topics: Animals; Anticarcinogenic Agents; Dysplastic Nevus Syndrome; Eflornithine; Fluorouracil; Humans; Mass Screening; Melanoma; Melanoma, Experimental; Patient Education as Topic; Retinoids; Risk Factors; Skin Neoplasms; Sunscreening Agents

1993

Trials

1 trial(s) available for fluorouracil and eflornithine

ArticleYear
Response and progression in recurrent malignant glioma.
    Neuro-oncology, 1999, Volume: 1, Issue:4

    Topics: Actuarial Analysis; Adolescent; Adult; Aged; Aged, 80 and over; Alitretinoin; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplatin; Combined Modality Therapy; Disease Progression; Disease-Free Survival; Eflornithine; Female; Fluorouracil; Glioblastoma; Glioma; Humans; Interferon-beta; Male; Menogaril; Middle Aged; Neoplasm Recurrence, Local; Procarbazine; Prognosis; Proportional Hazards Models; Texas; Treatment Outcome; Tretinoin

1999

Other Studies

12 other study(ies) available for fluorouracil and eflornithine

ArticleYear
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Schedule dependent potentiation of antitumor drug effects by alpha-difluoromethylornithine in human gastric carcinoma cells in vitro.
    Investigational new drugs, 1990, Volume: 8 Suppl 1

    Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Cell Cycle; Cell Survival; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Eflornithine; Fluorouracil; Humans; Ornithine Decarboxylase; Polyamines; Semustine; Stomach Neoplasms; Time Factors; Tumor Cells, Cultured

1990
In vitro response of a human colon tumor xenograft and a lung adenocarcinoma cell line to alpha-difluoromethylornithine alone and in combination with 5-fluorouracil and doxorubicin.
    Journal of surgical oncology, 1991, Volume: 48, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Colonic Neoplasms; Doxorubicin; Drug Screening Assays, Antitumor; Eflornithine; Fluorouracil; Humans; Lung Neoplasms; Neoplasm Transplantation; Tumor Cells, Cultured

1991
Conventional chemotherapeutic agents combined with DMSO or DFMO in treatment of rat prostate carcinoma.
    The Prostate, 1989, Volume: 15, Issue:3

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dimethyl Sulfoxide; Eflornithine; Fluorouracil; Male; Prostatic Neoplasms; Rats

1989
[Anticancer treatment with a combination of antimetabolites of polyamine and pyrimidine].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:10

    Topics: Animals; DNA Replication; Drug Therapy, Combination; Eflornithine; Floxuridine; Fluorouracil; Mice; Mice, Nude; Mitoguazone; Ornithine; Polyamines; Spermine; Stomach Neoplasms

1985
Combined therapy of polyamine antimetabolites and antitumor drugs for human gastric cancer xenotransplanted into nude mice.
    The Japanese journal of surgery, 1986, Volume: 16, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcinoma; Eflornithine; Floxuridine; Fluorouracil; Mice; Mice, Inbred BALB C; Mice, Nude; Mitoguazone; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Ornithine; Stomach Neoplasms

1986
In vitro assessment of antimicrobial agents against Toxoplasma gondii.
    The Journal of infectious diseases, 1988, Volume: 157, Issue:1

    Topics: Animals; Anti-Infective Agents; Cell Line; Clindamycin; Drug Resistance; Eflornithine; Fluorouracil; Leucomycins; Methotrexate; Organometallic Compounds; Pyrimethamine; Rats; Spiro Compounds; Sulfadiazine; Toxoplasma

1988
Consequences of ornithine decarboxylase inactivation by alpha-difluoromethylornithine and 5-fluorouracil on the growth of rabbit fibroblasts.
    Current eye research, 1985, Volume: 4, Issue:8

    Topics: Animals; Cell Division; Cells, Cultured; Eflornithine; Enzyme Activation; Fibroblasts; Fluorouracil; Ornithine; Ornithine Decarboxylase Inhibitors; Rabbits; Skin

1985
Effects of alpha-difluoromethylornithine and 5-fluorouracil on the proliferation of a human colon adenocarcinoma cell line.
    Cancer research, 1983, Volume: 43, Issue:9

    Topics: Adenocarcinoma; Antineoplastic Agents; Cell Cycle; Cell Line; Cell Survival; Eflornithine; Fluorouracil; Humans; Kinetics; Ornithine; Putrescine; Spermidine

1983
Chemoprevention of cancer of the upper respiratory tract of the Syrian golden hamster by aerosol administration of difluoromethylornithine and 5-fluorouracil.
    Cancer research, 2004, Apr-01, Volume: 64, Issue:7

    Topics: Administration, Inhalation; Aerosols; Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma, Squamous Cell; Cricetinae; Disease Models, Animal; Eflornithine; Fluorouracil; Laryngeal Neoplasms; Lung Neoplasms; Male; Mesocricetus; Methylnitrosourea; Pharyngeal Neoplasms

2004
Topical combination of diclofenac, calcipotriol, and difluoromethylornithine has beneficial effects comparable to 5-fluorouracil for the treatment of non-melanoma skin cancer in mice.
    Journal of chemotherapy (Florence, Italy), 2014, Volume: 26, Issue:2

    Topics: Administration, Topical; Animals; Antineoplastic Combined Chemotherapy Protocols; Calcitriol; Diclofenac; Eflornithine; Female; Fluorouracil; Mice; Mice, Hairless; Random Allocation; Skin Neoplasms

2014