fluorouracil and ebselen

fluorouracil has been researched along with ebselen in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's7 (63.64)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Negm, A; Shaaban, S; Sobh, MA; Wessjohann, LA1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Alejandre-Ramos, D; Bartolini, M; Bolognesi, ML; Fernández-Bolaños, JG; Lagunes, I; López, Ó; Maya, I; Monti, B; Padrón, JM; Peña-Altamira, LE; Roldán-Peña, JM1
Ashmawy, AM; Negm, A; Shaaban, S; Wessjohann, LA1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Chen, B; Fu, X; Jing, F; Li, B; Li, S; Liu, Y; Wang, X; Zhao, J2
Cariani, L; Di Bonaventura, G; Di Giulio, A; Lupetti, V; Muzzi, M; Piccirilli, A; Pompilio, A1

Other Studies

11 other study(ies) available for fluorouracil and ebselen

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Organoselenocyanates and symmetrical diselenides redox modulators: Design, synthesis and biological evaluation.
    European journal of medicinal chemistry, 2015, Jun-05, Volume: 97

    Topics: Anti-Infective Agents; Antineoplastic Agents; Antioxidants; Carboxylic Acids; Cell Survival; Cyanates; Drug Design; Hep G2 Cells; Humans; Organoselenium Compounds; Oxidation-Reduction; Selenium Compounds

2015
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents.
    European journal of medicinal chemistry, 2017, Sep-29, Volume: 138

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Cell Proliferation; Chalcogens; Cholinesterase Inhibitors; Dimerization; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Mice; Molecular Structure; Organoselenium Compounds; Peptide Fragments; Protein Aggregates; Structure-Activity Relationship; Tacrine

2017
Synthesis and biochemical studies of novel organic selenides with increased selectivity for hepatocellular carcinoma and breast adenocarcinoma.
    European journal of medicinal chemistry, 2019, Oct-01, Volume: 179

    Topics: Antineoplastic Agents; Antioxidants; Biphenyl Compounds; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Hep G2 Cells; Humans; Liver Neoplasms; MCF-7 Cells; Molecular Structure; Organoselenium Compounds; Picrates; Structure-Activity Relationship

2019
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Synthesis and in vitro antiproliferative evaluation of novel hybrids from 1,3,4-thiadiazole and benzisoselenazolone.
    Chemical & pharmaceutical bulletin, 2015, Volume: 63, Issue:6

    Topics: Antineoplastic Agents; Azoles; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Isoindoles; MCF-7 Cells; Neoplasms; Organoselenium Compounds; Thiadiazoles

2015
Synthesis and Biological Evaluation of Novel 1,3,4-thiadiazole Derivatives Incorporating Benzisoselenazolone Scaffold as Potential Antitumor Agents.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2016, Volume: 12, Issue:7

    Topics: Antineoplastic Agents; Azoles; Cell Line, Tumor; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Isoindoles; Organoselenium Compounds; Structure-Activity Relationship; Thiadiazoles

2016
Repurposing High-Throughput Screening Identifies Unconventional Drugs with Antibacterial and Antibiofilm Activities against Pseudomonas aeruginosa under Experimental Conditions Relevant to Cystic Fibrosis.
    Microbiology spectrum, 2023, 08-17, Volume: 11, Issue:4

    Topics: Anti-Bacterial Agents; Biofilms; Cystic Fibrosis; Drug Repositioning; Fluorouracil; High-Throughput Screening Assays; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Tirapazamine

2023