fluorouracil and dipyridamole

fluorouracil has been researched along with dipyridamole in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (18.46)	18.7374
1990's	34 (52.31)	18.2507
2000's	11 (16.92)	29.6817
2010's	7 (10.77)	24.3611
2020's	1 (1.54)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Gozalbes, R; Pineda-Lucena, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Akman, S; Cho, J; Doroshow, JH; Harrison, J; Leong, L; Margolin, K; Morgan, R; Raschko, J; Singh, D; Somlo, G	1
Kusumoto, H; Maehara, Y; Masuda, H; Sakaguchi, Y; Sugimachi, K; Takahashi, I; Yoshida, M	1
Hiddemann, W; Köhne-Wömpner, CH; Rustum, Y; Schmoll, HJ	1
Grem, JL	1
Taniki, T; Weber, G; Zhen, YS	1
Fukuda, I; Hioki, K; Iwanaga, T; Kameyama, M; Kato, T; Kikkawa, N; Mori, T; Utsunomiya, J; Yasutomi, M	1
Alberti, D; Arzoomanian, RZ; Bailey, H; Grem, JL; Spriggs, DR; Tombes, MB; Tutsch, KD; Wilding, G	1
Anzai, K; Ichinose, I; Kuroki, M; Mitsugi, K; Nakamura, M; Nakano, S; Niho, Y	1
Arcangeli, G; Bonera, F; Braga, M; Marini, G; Marpicati, P; Meriggi, F; Montini, E; Ragni, F; Simoncini, E; Zaniboni, A	1
Egorin, MJ; Forrest, A; Remick, S; Trump, DL; Tutsch, KD; Willson, JK	1
Gingrich, JR; Keane, TE; Poulton, SH; Rosner, GL; Walther, PJ	1
Emi, Y; Kohnoe, S; Kusumoto, T; Maehara, Y; Sakaguchi, Y; Sugimachi, K	1
Kosmidis, P; Kozatsani-Halvidi, D; Tsaroucha, E; Tsavaris, N	1
Harstrick, A; Köhne-Wömpner, CH; Poliwoda, H; Schmoll, HJ; Schöber, C; Wilke, H	1
Antonopoulos, A; Bacoyannis, C; Beldecos, D; Karvounis, N; Kosmidis, P; Mylonacis, N; Tsavaris, N; Valilis, P; Zamanis, N; Zinelis, A	1
Adelstein, D; Bauer, L; Boyett, J; Budd, GT; Bukowski, R; Grabowski, D; Jayaraj, A; Murthy, S; Weick, J	1
Alberti, DB; Bruggink, J; Fischer, PH; Grem, JL; Nieting, LM; Remick, SC; Tombes, MB; Trump, DL; Tutsch, KD; Willson, JK	1
Allegra, CJ; Fischer, PH; Grem, JL; Miller, EM; Mulcahy, RT	1
Milstone, LM; Schwartz, PM	1
Lönn, S; Lönn, U; Nylen, U; Winblad, G	1
Asoh, K; Kohno, K; Kuwano, M; Nogae, I; Saburi, Y; Sato, S	1
Fischer, PH; Grem, JL	3
Cao, SS; Zhen, YS	1
Marini, G; Marpicati, P; Montini, E; Palazzi, M; Pipino, G; Simoncini, E; Zaniboni, A	1
Farroukh, R; Gerlach, D; Hoffmann, W; Kress, M; Migeod, F; Seeber, S	1
Erbe, J; Plagemann, PG	1
Hirono, S; Ito, S	1
Czejka, MJ; Fogl, U; Jäger, W; Schernthaner, G; Schüller, J; Weiss, C	1
Bodenstein, H; Grem, J; Hiddemann, W; Köhne, CH; Lohrmann, HP; Schmitz-Hübner, U; Schöber, C; Schüller, J; Weiss, J; Wilke, H	1
Budd, GT; Bukowski, RM; Herzog, P	1
Bamberger, U; Chen, HX; Cheng, YC; Guo, X; Heckel, A	1
Sakuyama, T; Takahashi, N	1
Fukuda, I; Hioki, K; Imaoka, S; Kameyama, M; Kikkawa, N; Mori, T; Nakamori, S; Oshima, A; Utsunomiya, J; Yasutomi, M	1
Hidaka, K; Hisatsugu, T; Kohno, K; Komiyama, S; Kuwano, M; Sato, S	1
Barberi-Heyob, M; Griffon, G; Merlin, JL; Weber, B	1
Chifu, Y; Ishida, T; Kudo, J; Mitsugi, K; Nakano, S; Niho, Y; Sugimori, H	1
Etienne, MC; Fischel, JL; Formento, P; Haaz, MC; Milano, G; Renée, N	1
Fukuda, I; Hioki, K; Iwanaga, T; Kameyama, M; Kanno, H; Kikkawa, N; Mori, T; Ohashi, S; Oshima, A; Utsunomiya, J; Yasutomi, M; Yoden, Y	1
Bamberger, U; Boven, E; Feller, N; Jansen, WJ; Pinedo, HM; van der Wilt, CL	1
Köhne, CH; Schmoll, HJ; Schöffski, P; Wilke, H	1
Capizzi, RL; Case, L; Fernandes, DJ; Fleming, RA; Homesley, H; Loggie, BW; Morris, R; Muss, HB; Richards, F; Russell, GB; Smith, S	1
Baba, H; Emi, Y; Kohnoe, S; Maehara, Y; Sugimachi, K; Takahashi, I	1
Büchele, T; Dempke, W; Grothey, A; Schmoll, HJ	1
Addo, F; Allmer, C; Bernath, AM; Burch, PA; Cobau, CD; Ghosh, C; Goldberg, RM; Schroeder, G; Tschetter, LK; Windschitl, HE; Woodhouse, CL	1
Abrams, RA; Cameron, JL; Chakravarthy, A; Donehower, RC; Grochow, LB; Hruban, RH; Hurwitz, H; Jaffee, EM; Korman, LT; Lillemoe, KD; O'Reilly, S; Yeo, CJ; Zahurek, ML	1
Hofer, M; Pipalová, I; Pospísil, M; Vacek, A; Vácha, J; Weiterová, L; Znojil, V	1
Smart, T	1
Hofer, M; Holá, J; Netíková, J; Pospísil, M; Vacek, A; Weiterová, L; Znojil, V	1
Hofer, M; Holá, J; Pipalová, I; Pospísil, M; Vacek, A; Vácha, J; Weiterová, L; Znojil, V	1
Boyer, CR; Karjian, PL; Neuteboom, ST; Pegram, M; Wahl, GM	1
Hirano, H; Ikuma, H; Imai, T; Kadowaki, S; Mitsui, Y; Miyashita, K; Murata, T; Nakamura, T; Nobuoka, Y; Tanigawa, K; Taoka, H; Umino, W; Yamashita, M; Yoshimine, S	1
Barstis, JJ; Bendetti, JK; Isacoff, WH; Jazieh, AR; Macdonald, JS; Philip, PA	1

Reviews

6 review(s) available for fluorouracil and dipyridamole

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Biochemical modulation of fluorouracil by dipyridamole: preclinical and clinical experience. Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3 Topics: Colonic Neoplasms; Deoxyuridine; Dipyridamole; DNA Damage; DNA, Neoplasm; Drug Interactions; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Methotrexate; Nucleosides; Nucleotides; RNA, Neoplasm; Thymidine; Tumor Cells, Cultured; Uridine Monophosphate	1992
Modulation of cytotoxic drug activity by dipyridamole. Cancer treatment reviews, 1990, Volume: 17 Suppl A Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Cytarabine; Dipyridamole; Drug Interactions; Etoposide; Fluorouracil; Humans; Leucovorin; Methotrexate	1990
Enhancement of 5-fluorouracil's anticancer activity by dipyridamole. Pharmacology & therapeutics, 1989, Volume: 40, Issue:3 Topics: Animals; Biological Transport; Cell Line, Transformed; Dipyridamole; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; Humans; Neoplasms; Pyrimidine Nucleosides	1989
The dead end of 5-fluorouracil double modulation and promise of continuous infusion schedules in the treatment of metastatic colorectal cancer. The Journal of infusional chemotherapy, 1996,Fall, Volume: 6, Issue:4 Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Clinical Trials, Phase II as Topic; Colorectal Neoplasms; Combined Modality Therapy; Dipyridamole; Drug Administration Schedule; Drug Synergism; Enzyme Inhibitors; Female; Fluorouracil; Humans; Immunologic Factors; Infusions, Intravenous; Injections, Intravenous; Interferons; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Neoplasm Proteins; Nucleotides; Palliative Care; Phosphonoacetic Acid; Randomized Controlled Trials as Topic; Thymidylate Synthase	1996
Where do we stand with 5-fluorouracil? Seminars in oncology, 1999, Volume: 26, Issue:6 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Chronotherapy; Colorectal Neoplasms; Dipyridamole; Drug Synergism; Fluorouracil; Humans; Interferons; Leucovorin; Levamisole; Methotrexate; Phosphonoacetic Acid; Radiation-Sensitizing Agents; Trimetrexate; Zidovudine	1999

Trials

13 trial(s) available for fluorouracil and dipyridamole

Article	Year
Phase II trial of 5-fluorouracil, high-dose leucovorin calcium, and dipyridamole in advanced prostate cancer. Journal of cancer research and clinical oncology, 1992, Volume: 119, Issue:2 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Dipyridamole; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Prostatic Neoplasms	1992
A phase I trial of 5-fluorouracil, leucovorin, and dipyridamole given by concurrent 120-h continuous infusions. Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dipyridamole; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Drug Synergism; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Male; Middle Aged; Neoplasms; Stomach Neoplasms; Stomatitis	1992
Dipyridamole combination chemotherapy can be used safely in treating gastric cancer patients. Anti-cancer drugs, 1991, Volume: 2, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dipyridamole; Doxorubicin; Female; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms	1991
Multimodal biochemical modulation of 5-fluorouracil activity in advanced colorectal cancer with allopurinol, folinic acid and dipyridamol. Journal of chemotherapy (Florence, Italy), 1990, Volume: 2, Issue:2 Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Dipyridamole; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leucovorin; Male; Neoplasm Staging	1990
Phase I trial of dipyridamole with 5-fluorouracil and folinic acid. Cancer research, 1990, Nov-15, Volume: 50, Issue:22 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dipyridamole; Dose-Response Relationship, Drug; Drug Evaluation; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged	1990
Failure of orally administered dipyridamole to enhance the antineoplastic activity of fluorouracil in combination with leucovorin in patients with advanced colorectal cancer: a prospective randomized trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:5 Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dipyridamole; Disease Progression; Drug Administration Schedule; Female; Fluorouracil; Gastrointestinal Diseases; Headache; Humans; Leucovorin; Male; Middle Aged; Prospective Studies; Survival Rate; Treatment Outcome	1995
Phase I/II trial of dipyridamole, 5-fluorouracil, leukovorin, and mitoxantrone in metastatic breast cancer. Investigational new drugs, 1994, Volume: 12, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Breast Neoplasms; Dipyridamole; Drug Interactions; Fluorouracil; Granulocytes; Humans; Leucovorin; Middle Aged; Mitoxantrone; Neoplasm Metastasis	1994
[Some problems of TS measurement after administration of fluoropyrimidines in colorectal cancer. Kinki Cooperative Study Group of Chemotherapy for Colorectal Carcinoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:14 Topics: Adult; Aged; Antineoplastic Agents; Colorectal Neoplasms; Dipyridamole; Female; Fluorouracil; Humans; Male; Middle Aged; Thymidylate Synthase	1993
[Comparative study of the combined effect of HCFU and dipyridamole (DP) in colorectal carcinoma--TS inhibition rate. Kinki Cooperative Study Group of Chemotherapy for Colorectal Carcinoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:6 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dipyridamole; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunologic Factors; Japan; Male; Middle Aged; Thymidylate Synthase	1996
Phase I study of N-(phosphonacetyl)-L-aspartate with fluorouracil and with or without dipyridamole in patients with advanced cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 1996, Volume: 2, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Aspartate Carbamoyltransferase; Aspartic Acid; Dipyridamole; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Leukocytes; Male; Middle Aged; Neoplasms; Phosphonoacetic Acid; Uridine Triphosphate	1996
Treatment of advanced gastric cancer with 5-fluorouracil and cisplatin in combination with dipyridamole. International journal of oncology, 1998, Volume: 13, Issue:6 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dipyridamole; Female; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms; Treatment Outcome	1998
Phase II evaluation of continuous-infusion 5-fluorouracil, leucovorin, mitomycin-C, and oral dipyridamole in advanced measurable pancreatic cancer: a North Central Cancer Treatment Group Trial. American journal of clinical oncology, 2000, Volume: 23, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dipyridamole; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Mitomycin; Pancreatic Neoplasms; Survival Analysis; Treatment Failure	2000
Phase II trial of infusional fluorouracil, leucovorin, mitomycin, and dipyridamole in locally advanced unresectable pancreatic adenocarcinoma: SWOG S9700. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, May-01, Volume: 25, Issue:13 Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dipyridamole; Disease Progression; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Mitomycin; Pancreatic Neoplasms; Survival Analysis	2007

Other Studies

46 other study(ies) available for fluorouracil and dipyridamole

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
5-Fluorouracil's cytotoxicity is enhanced both in vitro and in vivo by concomitant treatment with hyperthermia and dipyridamole. Cancer chemotherapy and pharmacology, 1992, Volume: 29, Issue:4 Topics: Animals; Combined Modality Therapy; Dipyridamole; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; Humans; Hyperthermia, Induced; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Succinate Dehydrogenase; Tumor Cells, Cultured	1992
The emerging role for biomodulation of antineoplastic agents. Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3 Topics: Antineoplastic Agents; Aspartic Acid; Dipyridamole; Fluorouracil; Humans; Immunologic Factors; Interferon-alpha; Phosphonoacetic Acid	1992
Azidothymidine and dipyridamole as biochemical response modifiers: synergism with methotrexate and 5-fluorouracil in human colon and pancreatic carcinoma cells. Oncology research, 1992, Volume: 4, Issue:2 Topics: Adenocarcinoma; Cell Division; Cell Line; Cell Survival; Colonic Neoplasms; Dipyridamole; DNA Replication; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; Humans; Methotrexate; Pancreatic Neoplasms; Thymidine; Tumor Stem Cell Assay; Zidovudine	1992
[Potentiation of thymidylate synthetase (TS) inhibition by combined administration of HCFU and dipyridamole: preliminary report. Kinki Cooperative Study Group of Chemotherapy for Colorectal Carcinoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:7 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dipyridamole; Female; Fluorouracil; Humans; Male; Middle Aged; Pilot Projects; Thymidylate Synthase	1992
[5-FU-leucovorin and cisplatin sequential chemotherapy with dipyridamole for non-small cell lung cancer (NSCLC). A pilot study for 5 cases]. Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:8 Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Dipyridamole; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Lung Neoplasms; Male; Middle Aged; Pilot Projects	1991
Fluorouracil, high-dose folinic acid, low-dose alpha-2b interferon and dipyridamole in the treatment of advanced colorectal cancer. A pilot study. Journal of chemotherapy (Florence, Italy), 1991, Volume: 3, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dipyridamole; Female; Fluorouracil; Humans; Interferon alpha-2; Interferon-alpha; Leucovorin; Male; Middle Aged; Pilot Projects; Recombinant Proteins; Remission Induction	1991
Pharmacokinetic and pharmacodynamic analysis of fluorouracil during 72-hour continuous infusion with and without dipyridamole. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:11 Topics: Bone Marrow Diseases; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Fluorouracil; Humans; Infusions, Intravenous; Leukocyte Count; Mathematical Computing; Stomatitis	1991
The therapeutic impact of dipyridamole: chemopotentiation of the cytotoxic combination 5-fluorouracil/cisplatin in an animal model of human bladder cancer. The Journal of urology, 1991, Volume: 146, Issue:5 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line; Cisplatin; Dipyridamole; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Fluorouracil; Humans; Mice; Neoplasm Transplantation; Subrenal Capsule Assay; Urinary Bladder Neoplasms	1991
Therapeutic doses of dipyridamole failed to potentiate 5-fluorouracil tumor activity. Journal of chemotherapy (Florence, Italy), 1991, Volume: 3, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dipyridamole; Female; Fluorouracil; Humans; Male	1991
Phase I trial of 5-fluorouracil and dipyridamole administered by seventy-two-hour concurrent continuous infusion. Cancer research, 1990, May-01, Volume: 50, Issue:9 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dipyridamole; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms	1990
Interaction of deoxyuridine with fluorouracil and dipyridamole in a human colon cancer cell line. Biochemical pharmacology, 1989, Jan-01, Volume: 38, Issue:1 Topics: Cell Survival; Colonic Neoplasms; Deoxyuracil Nucleotides; Deoxyuridine; Dipyridamole; DNA; DNA Damage; Drug Interactions; Fluorouracil; Humans; RNA; Tumor Cells, Cultured	1989
Dipyridamole potentiates the growth-inhibitory action of methotrexate and 5-fluorouracil in human keratinocytes in vitro. The Journal of investigative dermatology, 1989, Volume: 93, Issue:4 Topics: Cell Division; Dipyridamole; DNA; Drug Synergism; Epidermal Cells; Fluorouracil; Humans; Infant, Newborn; Keratins; Male; Methotrexate; Thymidine	1989
5-Fluoropyrimidine-induced DNA damage in human colon adenocarcinoma and its augmentation by the nucleoside transport inhibitor dipyridamole. Cancer research, 1989, Mar-01, Volume: 49, Issue:5 Topics: Adenocarcinoma; Colonic Neoplasms; Dipyridamole; DNA; DNA Damage; Floxuridine; Fluorouracil; Humans; Methotrexate; Nucleosides; Tumor Cells, Cultured	1989
Potentiation of some anticancer agents by dipyridamole against drug-sensitive and drug-resistant cancer cell lines. Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:5 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Line; Dactinomycin; Dihydropyridines; Dipyridamole; Drug Resistance; Drug Synergism; Fluorouracil; Humans; Membrane Glycoproteins; Tumor Cells, Cultured; Vincristine	1989
Potentiation of antimetabolite antitumor activity in vivo by dipyridamole and amphotericin B. Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:3 Topics: Amphotericin B; Animals; Antimetabolites, Antineoplastic; Dipyridamole; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Lung Neoplasms; Male; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Sarcoma 180; Uterine Cervical Neoplasms	1989
5-Fluorouracil and dipyridamole in metastatic breast cancer: a pilot study. Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dipyridamole; Drug Tolerance; Female; Fluorouracil; Humans; Middle Aged; Neoplasm Metastasis; Pilot Projects	1989
Alteration of fluorouracil metabolism in human colon cancer cells by dipyridamole with a selective increase in fluorodeoxyuridine monophosphate levels. Cancer research, 1986, Volume: 46, Issue:12 Pt 1 Topics: Cells, Cultured; Colonic Neoplasms; Deoxyuracil Nucleotides; Deoxyuridine; Dipyridamole; DNA; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Ribonucleotides; Time Factors; Uridine Triphosphate	1986
[Sequential treatment of progressive metastatic colorectal cancer with 5-fluorouracil/folinic acid, dipyramidole and mitomycin C]. Onkologie, 1988, Volume: 11 Suppl 2 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dipyridamole; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Male; Middle Aged; Mitomycin; Mitomycins; Neoplasm Metastasis	1988
Augmentation of 5-fluorouracil cytotoxicity in human colon cancer cells by dipyridamole. Cancer research, 1985, Volume: 45, Issue:7 Topics: Cell Division; Cell Line; Cell Survival; Colonic Neoplasms; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Fluorouracil; Humans; Nucleosides; Thymine Nucleotides	1985
The deoxyribonucleoside transport systems of cultured Novikoff rat hepatoma cells. Journal of cellular physiology, 1974, Volume: 83, Issue:3 Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cell Membrane Permeability; Cells, Cultured; Cytochalasin B; Deoxyribonucleosides; Deoxyuridine; Depression, Chemical; Dipyridamole; Fluorouracil; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Rats; Thymidine; Time Factors; Tritium	1974
[Two cases with microangiopathic hemolytic anemia caused by anti-cancer drugs who improved rapidly after administration of aspirin and dipyridamole]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1982, Volume: 23, Issue:5 Topics: Adult; Aged; Anemia, Hemolytic; Antineoplastic Agents; Aspirin; Chromomycin A3; Dipyridamole; Female; Fluorouracil; Humans; Male; Mitomycin; Mitomycins; Stomach Neoplasms	1982
Clinical pharmacokinetics of 5-fluorouracil. Influence of the biomodulating agents interferon, dipyridamole and folinic acid alone and in combination. Arzneimittel-Forschung, 1993, Volume: 43, Issue:3 Topics: Aged; Chromatography, High Pressure Liquid; Dipyridamole; Drug Combinations; Drug Interactions; Female; Fluorouracil; Humans; Immunologic Factors; Interferons; Leucovorin; Male; Middle Aged	1993
BIBW 22, a dipyridamole analogue, acts as a bifunctional modulator on tumor cells by influencing both P-glycoprotein and nucleoside transport. Cancer research, 1993, May-01, Volume: 53, Issue:9 Topics: Affinity Labels; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Membrane Permeability; Dipyridamole; Drug Synergism; Fluorouracil; Humans; Membrane Glycoproteins; Morpholines; Nucleosides; Photochemistry; Thymidine; Triamterene; Tumor Cells, Cultured; Vincristine	1993
[TS inhibition rate and flow cytometric analysis of DNA content in preoperative chemotherapy with biochemical modulator]. Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21 Suppl 1 Topics: Administration, Oral; Adult; Aged; Chemotherapy, Adjuvant; Colorectal Neoplasms; Dipyridamole; DNA, Neoplasm; Female; Flow Cytometry; Fluorouracil; Humans; Male; Middle Aged; Preoperative Care; Thymidylate Synthase	1994
Differentially potentiating effects by dipyridamole on cytotoxicity of 5-fluorouracil against three human maxillary cancer cell lines derived from a single tumor. Anti-cancer drug design, 1993, Volume: 8, Issue:4 Topics: Cell Survival; Dipyridamole; Drug Synergism; Fluorodeoxyuridylate; Fluorouracil; Humans; Maxillary Neoplasms; Tumor Cells, Cultured; Uridine Triphosphate	1993
Sequence-dependent growth-inhibitory effects of the in vitro combination of fluorouracil, cisplatin, and dipyridamole. Cancer chemotherapy and pharmacology, 1993, Volume: 33, Issue:2 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Cisplatin; Dipyridamole; Drug Administration Schedule; Drug Synergism; Female; Fluorouracil; Humans; Tumor Cells, Cultured	1993
[5-fluorouracil + low-dose leucovorin and cisplatin sequential chemotherapy with dipyridamole for advanced nonresectable squamous cell carcinoma of the lung: a case report]. Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:2 Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dipyridamole; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intravenous; Injections, Intravenous; Leucovorin; Lung Neoplasms; Male; Middle Aged; Remission Induction	1993
Impact of different fluorouracil biochemical modulators on cellular dihydropyrimidine dehydrogenase. Cancer chemotherapy and pharmacology, 1996, Volume: 38, Issue:1 Topics: Allopurinol; Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Division; Cisplatin; Dihydrouracil Dehydrogenase (NADP); Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Oxidoreductases; Pancreatic Neoplasms; Platelet Aggregation Inhibitors; Tumor Cells, Cultured	1996
The influence of BIBW22BS, a dipyridamole derivative, on the antiproliferative effects of 5-fluorouracil, methotrexate and gemcitabine in vitro and in human tumour xenografts. European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:13-14 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Deoxycytidine; Dipyridamole; Doxorubicin; Drug Resistance; Female; Floxuridine; Fluorouracil; Gemcitabine; Humans; Methotrexate; Mice; Mice, Nude; Morpholines; Neoplasms; Neoplasms, Experimental; Protein Binding; Transplantation, Heterologous; Triamterene; Tumor Cells, Cultured; Vincristine	1995
Intensified adjuvant combined modality therapy for resected periampullary adenocarcinoma: acceptable toxicity and suggestion of improved 1-year disease-free survival. International journal of radiation oncology, biology, physics, 2000, Nov-01, Volume: 48, Issue:4 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Dipyridamole; Disease-Free Survival; Duodenal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Male; Middle Aged; Mitomycin; Neoplasm Recurrence, Local; Pancreatic Neoplasms; Pancreaticoduodenectomy; Radiotherapy Dosage; Radiotherapy, Adjuvant; Time Factors	2000
Influence of the joint treatment with granulocyte colony-stimulating factor and drugs elevating extracellular adenosine on erythropoietic recovery following 5-fluorouracil-induced haematotoxicity in mice. European journal of haematology, 2000, Volume: 65, Issue:5 Topics: Adenosine; Adenosine Monophosphate; Animals; Antimetabolites; Dipyridamole; Drug Therapy, Combination; Erythrocyte Count; Erythrocytes; Erythroid Precursor Cells; Erythropoiesis; Fluorouracil; Granulocyte Colony-Stimulating Factor; Hemoglobins; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Phosphodiesterase Inhibitors; Reticulocytes; Time Factors	2000
Beyond hydroxyurea. GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:9 Topics: Animals; Antiviral Agents; Benzamidines; Dipyridamole; Disease Models, Animal; Floxuridine; Fluorouracil; Humans; Hydroxamic Acids; Hydroxyurea; Mice; Murine Acquired Immunodeficiency Syndrome; Ribonucleotide Reductases	1995
Drugs elevating extracellular adenosine enhance cell cycling of hematopoietic progenitor cells as inferred from the cytotoxic effects of 5-fluorouracil. Experimental hematology, 2001, Volume: 29, Issue:5 Topics: Adenosine; Adenosine Monophosphate; Animals; Antimetabolites, Antineoplastic; Bone Marrow Diseases; Cell Cycle; Colony-Forming Units Assay; Dipyridamole; Drug Synergism; Extracellular Space; Fluorouracil; Hematopoietic Stem Cells; Male; Mice; Prodrugs; Receptors, Purinergic P1	2001
Combination of drugs elevating extracellular adenosine with granulocyte colony-stimulating factor promotes granulopoietic recovery in the murine bone marrow after 5-fluorouracil treatment. Physiological research, 2001, Volume: 50, Issue:5 Topics: Adenosine; Adenosine Monophosphate; Animals; Bone Marrow; Bone Marrow Cells; Dipyridamole; Drug Interactions; Extracellular Space; Fluorouracil; Granulocyte Colony-Stimulating Factor; Granulocytes; Hematopoiesis; Hematopoietic Stem Cells; Humans; Macrophages; Male; Mice; Recombinant Proteins	2001
Nucleoside transport inhibitors, dipyridamole and p-nitrobenzylthioinosine, selectively potentiate the antitumor activity of NB1011. Anti-cancer drugs, 2002, Volume: 13, Issue:1 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Bromodeoxyuridine; Carrier Proteins; Cell Survival; Colonic Neoplasms; Dipyridamole; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; Humans; Membrane Proteins; Nucleoside Transport Proteins; Quinazolines; Thioinosine; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured	2002
[Adjuvant chemotherapy for unresectable locally advanced pancreatic cancer in light of its characteristics]. Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:9 Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Deoxycytidine; Dipyridamole; Drug Administration Schedule; Female; Fluorouracil; Gemcitabine; Humans; Leucovorin; Male; Middle Aged; Mitomycin; Neoplasm Staging; Pancreatic Neoplasms	2004