fluorouracil and coumarin

fluorouracil has been researched along with coumarin in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's3 (27.27)29.6817
2010's5 (45.45)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Xu, Z; Zhang, L1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Petrylak, D; Yagoda, A1
Kaniwa, N; Murayama, N; Nakajima, Y; Ohno, Y; Ozawa, S; Sai, K; Sawada , J1
Chiba, M; Ishii, Y; Yamada, H; Yamamiya, I; Yoshisue, K1
Cheng, Y; Miao, W; Wang, F; Wang, H1
Ding, C; Fu, J; Wang, C; Zhou, S1

Reviews

2 review(s) available for fluorouracil and coumarin

ArticleYear
Coumarin-containing hybrids and their anticancer activities.
    European journal of medicinal chemistry, 2019, Nov-01, Volume: 181

    Topics: Animals; Antineoplastic Agents; Coumarins; Drug Design; Drug Discovery; Humans; Neoplasms; Structure-Activity Relationship

2019
Cytotoxic chemotherapy for advanced hormone-resistant prostate cancer.
    Cancer, 1993, Feb-01, Volume: 71, Issue:3 Suppl

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bone Neoplasms; Cisplatin; Clinical Trials as Topic; Coumarins; Doxorubicin; Drug Administration Schedule; Drug Resistance; Fluorouracil; Humans; Intercalating Agents; Male; Methotrexate; Neoplasm Staging; Polyamines; Prostate-Specific Antigen; Prostatic Neoplasms; Remission Induction; Somatostatin

1993

Other Studies

9 other study(ies) available for fluorouracil and coumarin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Expression of CYP2A6 in tumor cells augments cellular sensitivity to tegafur.
    Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:5

    Topics: Antimetabolites, Antineoplastic; Aryl Hydrocarbon Hydroxylases; Cell Division; Colonic Neoplasms; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Fluorouracil; Gene Expression; Humans; Hydroxylation; Microsomes; Mixed Function Oxygenases; Tegafur; Transfection; Tumor Cells, Cultured

2001
Effect of CYP2A6 genetic polymorphism on the metabolic conversion of tegafur to 5-fluorouracil and its enantioselectivity.
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:9

    Topics: Cell Line; Coumarins; Cytochrome P-450 CYP2A6; DNA, Complementary; Escherichia coli; Fluorouracil; Humans; Microsomes, Liver; Nicotine; Polymorphism, Genetic; Sf9 Cells; Tegafur

2014
A Self-Assembled Coumarin-Anchored Dendrimer for Efficient Gene Delivery and Light-Responsive Drug Delivery.
    Biomacromolecules, 2018, 06-11, Volume: 19, Issue:6

    Topics: Antineoplastic Agents; Cell Line, Tumor; Coumarins; Dendrimers; Drug Delivery Systems; Fluorouracil; Gene Transfer Techniques; HEK293 Cells; Humans; Nanostructures; Neoplasm Proteins; Neoplasms; Phototherapy; TNF-Related Apoptosis-Inducing Ligand

2018
UV-light cross-linked and pH de-cross-linked coumarin-decorated cationic copolymer grafted mesoporous silica nanoparticles for drug and gene co-delivery in vitro.
    Materials science & engineering. C, Materials for biological applications, 2020, Volume: 108

    Topics: Animals; Biocompatible Materials; Cations; Chlorocebus aethiops; COS Cells; Coumarins; Cross-Linking Reagents; Drug Carriers; Drug Delivery Systems; Fluorouracil; Gene Transfer Techniques; Hemolysis; Humans; Hydrogen-Ion Concentration; Hydrolysis; MCF-7 Cells; Nanoparticles; Plasmids; Polymers; Silicon Dioxide; Tumor Suppressor Protein p53; Ultraviolet Rays

2020