fluorouracil and catechin

fluorouracil has been researched along with catechin in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (30.77)29.6817
2010's12 (46.15)24.3611
2020's6 (23.08)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
El-Gohary, NS; Shaaban, MI2
Abdel-Rahman, SA; El-Ashry, SM; El-Bendary, ER; El-Gohary, NS; Shaaban, MI1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Aoi, J; Fushiya, S; Takano, F; Tanaka, T; Yahagi, N1
Benghuzzi, H; May, M; Norwood, AA; Tan, M; Tucci, M1
Benghuzzi, H; Norwood, AA; Tucci, M1
Cabezas-Herrera, J; Campo, LS; Navarro-Perán, E; Rodríguez-López, JN1
Chen, TC; Hofman, FM; Lee, AS; Pyrko, P; Schönthal, AH1
Liang, G; Tang, HH; Zhou, M1
Braconi, C; Henson, R; Lang, M; Patel, T1
Du, J; Gu, C; Han, M; Lu, W; Qiao, J; Shang, W; Wang, W; Yin, W; Zhu, M1
Bastian, SE; Bindon, KA; Cheah, KY; Howarth, GS; Kennedy, JA1
Goel, A; Okugawa, Y; Toden, S; Tovar-Camargo, OA; Tran, HM1
Han, J; Li, D; Liu, G; Liu, M; Wang, B; Wang, Z; Yuan, L; Zhang, M1
Azuma, T; Ekuni, D; Kobayashi, T; Maruyama, T; Miyai, H; Mizuno, H; Morita, M; Sugiura, Y; Tomofuji, T; Yoneda, T1
La, X; Li, H; Li, Z; Yang, Y; Zhang, L1
Gómez García, F; López Jornet, P; Pons-Fuster López, E1
Chen, J; Chen, Z; Di, L; Hu, L; Huang, J; Li, J; Qiao, H; Wang, H; Wang, R; Yang, M1
Agostini, M; Crotti, S; Moracci, L; Traldi, P1
Bae, SJ; Ha, KT; Han, JH; Jang, SB; Kim, HJ; Kim, M; Lee, IK; Ryu, D1
Agostini, M; Benetti, F; Biccari, A; Crotti, S; Gaio, E; Moracci, L; Pucciarelli, S; Sensi, F; Traldi, P1
Cen, J; Dong, J; Huang, J; Huang, K; Liang, Y; Lu, X; Pan, Y; Shu, G; Ye, S; Ye, W; Zhang, J; Zheng, Z; Zhou, M1
Ene, AG; Ficai, A; Ficai, D; Vladu, AF1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1

Reviews

1 review(s) available for fluorouracil and catechin

ArticleYear
Combination Therapy Using Polyphenols: An Efficient Way to Improve Antitumoral Activity and Reduce Resistance.
    International journal of molecular sciences, 2022, Sep-06, Volume: 23, Issue:18

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; beta Catenin; Breast Neoplasms; Catechin; Curcumin; Cytostatic Agents; Doxorubicin; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Fluorouracil; Humans; Liver Neoplasms; Polyphenols; Receptors, Estrogen; Resveratrol

2022

Other Studies

25 other study(ies) available for fluorouracil and catechin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Synthesis and biological evaluation of a new series of benzimidazole derivatives as antimicrobial, antiquorum-sensing and antitumor agents.
    European journal of medicinal chemistry, 2017, May-05, Volume: 131

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Bacteria; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fungi; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

2017
Synthesis, antimicrobial, antiquorum-sensing and antitumor activities of new benzimidazole analogs.
    European journal of medicinal chemistry, 2017, Sep-08, Volume: 137

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Aspergillus fumigatus; Bacillus cereus; Benzimidazoles; Candida albicans; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Escherichia coli; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Quorum Sensing; Staphylococcus aureus; Structure-Activity Relationship

2017
Synthesis, antimicrobial, antiquorum-sensing, antitumor and cytotoxic activities of new series of cyclopenta(hepta)[b]thiophene and fused cyclohepta[b]thiophene analogs.
    European journal of medicinal chemistry, 2017, Nov-10, Volume: 140

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Bacteria; Cell Line; Cell Proliferation; Cycloheptanes; Cyclopentanes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fungi; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship; Thiophenes

2017
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Protective effect of (+)-catechin against 5-fluorouracil-induced myelosuppression in mice.
    Toxicology, 2004, Sep-01, Volume: 201, Issue:1-3

    Topics: Animals; Blood; Bone Marrow; Catechin; Female; Flow Cytometry; Fluorouracil; Immunosuppressive Agents; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Spleen

2004
Comparison of potential chemotherapeutic agents, 5-fluoruracil, green tea, and thymoquinone on colon cancer cells.
    Biomedical sciences instrumentation, 2006, Volume: 42

    Topics: Antineoplastic Agents; Benzoquinones; Catechin; Cell Proliferation; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Feasibility Studies; Fluorouracil; Plant Extracts; Tea; Treatment Outcome

2006
A comparison of 5-fluorouracil and natural chemotherapeutic agents, EGCG and thymoquinone, delivered by sustained drug delivery on colon cancer cells.
    Biomedical sciences instrumentation, 2007, Volume: 43

    Topics: Adenocarcinoma; Antineoplastic Agents; Benzoquinones; Catechin; Cell Proliferation; Cell Survival; Colonic Neoplasms; Delayed-Action Preparations; Dose-Response Relationship, Drug; Fluorouracil; Humans; Phytotherapy; Plant Extracts; Treatment Outcome; Tumor Cells, Cultured

2007
Effects of folate cycle disruption by the green tea polyphenol epigallocatechin-3-gallate.
    The international journal of biochemistry & cell biology, 2007, Volume: 39, Issue:12

    Topics: Adenosine; Apoptosis; Caco-2 Cells; Camellia sinensis; Caspase 3; Catechin; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; DNA Replication; Fluorouracil; Folic Acid Antagonists; Gene Expression; Humans; Hypoxanthine; Leucovorin; Models, Biological; NF-kappa B; Protein Binding; Receptor, Adenosine A3; Tetrahydrofolate Dehydrogenase; Thymine; Transcription, Genetic

2007
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.
    Cancer research, 2007, Oct-15, Volume: 67, Issue:20

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Caspase 7; Catechin; Cell Growth Processes; Cell Line, Tumor; Dacarbazine; Down-Regulation; Drug Screening Assays, Antitumor; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Fluorouracil; Glioblastoma; Heat-Shock Proteins; Humans; Irinotecan; Molecular Chaperones; RNA, Small Interfering; Temozolomide; Transcription Factor CHOP; Transfection

2007
[Impact of epigallocatechin gallate on gene expression profiles of human hepatocellular carcinoma cell lines BEL7404/ADM and BEL7402/5-FU].
    Ai zheng = Aizheng = Chinese journal of cancer, 2008, Volume: 27, Issue:10

    Topics: Anticarcinogenic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cyclin G1; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Profiling; Humans; Liver Neoplasms; Oligonucleotide Array Sequence Analysis; Vault Ribonucleoprotein Particles

2008
Epigallocatechin-gallate modulates chemotherapy-induced apoptosis in human cholangiocarcinoma cells.
    Liver international : official journal of the International Association for the Study of the Liver, 2009, Volume: 29, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Bile Duct Neoplasms; Blotting, Western; Camellia sinensis; Catechin; Cell Line, Tumor; Cholangiocarcinoma; Cytochromes c; Deoxycytidine; Fluorouracil; Gemcitabine; Humans; Immunohistochemistry; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Mitomycin; Plant Extracts

2009
Effect of green tea on pharmacokinetics of 5-fluorouracil in rats and pharmacodynamics in human cell lines in vitro.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011, Volume: 49, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Area Under Curve; Camellia sinensis; Catechin; Cell Line, Tumor; Cell Survival; Drug Synergism; Fluorouracil; Humans; Male; Neoplasms; Plant Extracts; Rats; Rats, Sprague-Dawley

2011
Low molecular weight procyanidins from grape seeds enhance the impact of 5-Fluorouracil chemotherapy on Caco-2 human colon cancer cells.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Antineoplastic Agents; Antioxidants; Biflavonoids; Caco-2 Cells; Catechin; Cell Survival; Colonic Neoplasms; Drug Synergism; Fluorouracil; Grape Seed Extract; Humans; Molecular Weight; Proanthocyanidins

2014
Epigallocatechin-3-gallate targets cancer stem-like cells and enhances 5-fluorouracil chemosensitivity in colorectal cancer.
    Oncotarget, 2016, Mar-29, Volume: 7, Issue:13

    Topics: Animals; Antineoplastic Agents; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Fluorouracil; Humans; Mice; Mice, Nude; Neoplastic Stem Cells

2016
Competitive binding of (-)-epigallocatechin-3-gallate and 5-fluorouracil to human serum albumin: A fluorescence and circular dichroism study.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2017, Feb-15, Volume: 173

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Binding Sites; Binding, Competitive; Catechin; Circular Dichroism; Drug Synergism; Fluorouracil; Humans; Ibuprofen; Protein Structure, Secondary; Serum Albumin, Human; Spectrometry, Fluorescence; Thermodynamics; Warfarin

2017
Topical application of ointment containing 0.5% green tea catechins suppresses tongue oxidative stress in 5-fluorouracil administered rats.
    Archives of oral biology, 2017, Volume: 82

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Topical; Animals; Antioxidants; Catechin; Deoxyguanosine; Fluorouracil; Male; NF-E2-Related Factor 2; Ointments; Oxidative Stress; Rats; Rats, Wistar; Tea; Tongue

2017
(-)-Epigallocatechin Gallate (EGCG) Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU by Inhibiting GRP78/NF-κB/miR-155-5p/MDR1 Pathway.
    Journal of agricultural and food chemistry, 2019, Mar-06, Volume: 67, Issue:9

    Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Catechin; Colorectal Neoplasms; DNA Damage; Drug Interactions; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Fluorouracil; Gene Expression; HCT116 Cells; Heat-Shock Proteins; Humans; MicroRNAs; NF-kappa B; Signal Transduction

2019
Combination of 5-Florouracil and polyphenol EGCG exerts suppressive effects on oral cancer cells exposed to radiation.
    Archives of oral biology, 2019, Volume: 101

    Topics: Catechin; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Therapy, Combination; Fluorouracil; Humans; Mouth Neoplasms; Radiation

2019
Enhanced anti-colon cancer efficacy of 5-fluorouracil by epigallocatechin-3- gallate co-loaded in wheat germ agglutinin-conjugated nanoparticles.
    Nanomedicine : nanotechnology, biology, and medicine, 2019, Volume: 21

    Topics: Animals; Apoptosis; Catechin; Colonic Neoplasms; Fluorouracil; HT29 Cells; Humans; Mice; Nanoconjugates; Neovascularization, Pathologic; Wheat Germ Agglutinins; Xenograft Model Antitumor Assays

2019
Mass spectrometry in the study of molecular complexes between 5-fluorouracil and catechins.
    Journal of mass spectrometry : JMS, 2021, Volume: 56, Issue:1

    Topics: Antineoplastic Agents; Catechin; Chromatography, Liquid; Flow Injection Analysis; Fluorouracil; Herb-Drug Interactions; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tea

2021
Targeting Lactate Dehydrogenase A with Catechin Resensitizes SNU620/5FU Gastric Cancer Cells to 5-Fluorouracil.
    International journal of molecular sciences, 2021, May-20, Volume: 22, Issue:10

    Topics: Apoptosis; Catechin; Cell Line, Tumor; Drug Resistance, Neoplasm; Fluorouracil; Glycolysis; Humans; Lactate Dehydrogenase 5; Reactive Oxygen Species; Stomach; Stomach Neoplasms

2021
An investigation on [5 fluorouracil and epigallocatechin-3-gallate] complex activity on HT-29 cell death and its stability in gastrointestinal fluid.
    Oncotarget, 2022, Volume: 13

    Topics: Catechin; Cell Survival; Fluorouracil; HT29 Cells; Humans

2022
Chitosan-Gelatin-EGCG Nanoparticle-Meditated LncRNA TMEM44-AS1 Silencing to Activate the P53 Signaling Pathway for the Synergistic Reversal of 5-FU Resistance in Gastric Cancer.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022, Volume: 9, Issue:22

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Catechin; Cell Line, Tumor; Chitosan; Drug Resistance, Neoplasm; Fluorouracil; Gelatin; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; MicroRNAs; Nanoparticles; Repressor Proteins; RNA; RNA, Antisense; RNA, Long Noncoding; Signal Transduction; Stomach Neoplasms; Tumor Suppressor Protein p53

2022
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007