fluorouracil and carmofur

fluorouracil has been researched along with carmofur in 214 studies

Research

Studies (214)

TimeframeStudies, this research(%)All Research%
pre-1990101 (47.20)18.7374
1990's54 (25.23)18.2507
2000's37 (17.29)29.6817
2010's15 (7.01)24.3611
2020's7 (3.27)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Eguchi, S; Hara, Y; Kono, A; Matsushima, Y; Tanaka, M2
Kobari, T; Kobayashi, H; Kumakura, M; Miyama, Y; Namekawa, H; Shirakawa, I; Tan, K; Ujiie, A; Watanabe, S; Yamamoto, H1
Kuzuhara, S2
Imai, Y; Ito, J; Kobayashi, K; Okamoto, M; Tagawa, K; Taniguchi, M; Tanzawa, Y; Toda, N; Unuma, T; Uta, Y1
Hasegawa, N; Kawamoto, K; Uemura, T1
Kuroda, Y; Ohkuma, R; Ohsato, K1
Amano, H; Awano, T; Funami, Y; Koide, Y; Matsubara, H; Matsushita, K; Nakaichi, H; Ochiai, T; Okuyama, K; Tohnosu, N1
Kusumoto, T; Miyagi, M; Nakashima, T1
Hayahara, N; Horii, A; Kashihara, N; Kawakita, J; Kishimoto, T; Maekawa, M; Morikawa, Y; Nishijima, T; Wada, S; Yasumoto, R1
Fukuda, I; Hioki, K; Iwanaga, T; Kameyama, M; Kato, T; Kikkawa, N; Mori, T; Utsunomiya, J; Yasutomi, M1
Kozuka, T; Matsunaga, T; Matsuoka, H; Miyaguchi, M; Nakai, Y; Nishimura, T; Sakai, S; Sato, T; Tanabe, M; Yoshino, K2
Hirayama, F; Horiuchi, Y; Uekama, K1
Akazai, Y; Fuchimoto, S; Iwagaki, H; Matsubara, N; Orita, K; Shiiki, S; Watanabe, T1
Abe, O; Arisawa, Y; Fujita, S; Ishibiki, K; Josui, K; Kodaira, S; Kubota, T; Mabuchi, K; Suto, A; Yamamoto, T1
Akiyama, S; Ito, A; Ito, K; Kondo, K; Satta, T; Takagi, H; Watanabe, T; Yamauchi, M1
Chang, YC; Kohno, H; Nagasue, N; Nakamura, T; Ogawa, Y; Sasaki, K; Takahashi, M; Yukaya, H1
Hojo, K; Makuuchi, M; Moriya, Y; Sugihara, K1
Emi, Y; Kohnoe, S; Kusumoto, T; Maehara, Y; Sakaguchi, Y; Sugimachi, K1
Hori, M; Koizumi, J; Shiraishi, H; Suzuki, T; Uchida, K1
Katsuki, Y; Nishimura, A; Tsuji, Y; Yasuda, T1
Imai, S; Morimoto, H; Nio, Y; Shiraishi, T; Tobe, T; Tseng, CC; Tsubono, M1
Gröhn, P; Heinonen, E; Kumpulainen, E; Länsimies, H; Lantto, A; Numminen, S; Pyrhönen, S; Salmi, R1
Nakano, H; Nakatani, K; Nishiwada, T; Okumura, T; Sawada, H; Shino, Y; Watanabe, A; Yamada, Y; Yano, T1
Furusawa, M; Hara, Y; Kameda, K; Nakane, H; Nohtsuka, T; Saeki, K; Seo, Y; Sonoda, T; Tomoda, H; Tsujitani, S1
Aoki, Y; Fujita, H; Saitoh, H; Shinohara, Y; Takagi, S1
Abe, O; Hattori, T; Kikuchi, K; Komi, N; Kondo, T; Kunii, Y; Nakajima, T; Nakazato, H; Taguchi, T; Tanabe, T1
Gröhn, P; Heinonen, E; Kivinen, S; Sipilä, P; Vesala, J1
Kimura, T; Kusama, S; Morioka, Y; Muto, T; Ogawa, N; Tomiyama, J1
Akazawa, S; Fujiki, T; Futatsugi, K; Kanda, Y; Muraoka, M; Nakajima, T; Naoi, Y; Saifuku, K; Suzuki, F; Yamamoto, K1
Kanematsu, T; Shimada, M; Sugimachi, K; Takenaka, K1
Hamazaki, K; Mimura, H; Mori, M; Orita, K1
Azuma, T; Imasaka, K; Nagai, T; Ueda, H1
Katsumi, T; Murayama, K1
Masui, Y; Okamura, S; Okazaki, T; Sugimoto, O; Sugino, M; Ueki, M; Ushiroyama, T; Yamada, T; Yamazaki, H; Yanagawa, Y1
Kusumoto, T; Maehara, Y; Sakaguchi, Y; Sugimachi, K1
Horie, M; Kawada, Y; Kobayashi, S; Komeda, H; Kuriyama, M; Takahashi, Y; Yamada, S1
Fukushima, K1
Higashi, H; Kanematsu, T; Matsumata, T; Sugimachi, K; Takenaka, K; Yoshida, Y1
Suenaga, M1
Kanazawa, A; Kawaguchi, T; Machida, R; Nagai, T; Takayama, K1
Takahashi, M1
Itoh, A; Kitai, S; Sawai, K; Seiki, K; Shimamura, Y; Shimotsuma, M; Shioaki, Y; Takahashi, T; Taniguchi, H; Yamaguchi, T1
Hori, M; Kano, T; Mizuno, K; Nishida, Y; Ohta, M; Okamoto, E; Sakakibara, K; Tokuhashi, Y; Tomita, Y; Yoshio, G1
Kato, T; Ota, K1
Hattori, T; Hirabayashi, N; Kirihara, Y; Niimoto, M; Nishiyama, M; Nosoh, Y; Saeki, T; Takagami, S1
Amino, S; Ebata, K; Hashimoto, S; Horiuchi, J; Ikeda, M; Kaneda, K; Matsuda, T; Mikuriya, S; Okawa, T1
Sawada, M1
Abe, M; Hirai, K; Kawazoe, Y; Kumagai, M; Tanikawa, K; Yamashita, K1
Fuse, M; Kondo, H; Mori, K; Ohta, Y; Onji, M; Yamashita, Y1
Aoki, N1
Dokiya, T; Hashimoto, S; Kunieda, E; Miyamoto, H; Shigematsu, N; Tominaga, J1
Ichihashi, H; Koike, A; Nakazato, H1
Ichihashi, H; Imaizumi, M; Kondo, T; Takagi, H; Terabe, K; Watanabe, T; Yamauchi, M1
Nakanishi, Y1
Anai, H; Kusumoto, H; Maehara, Y; Masuda, H; Sugimachi, K1
Hattori, T; Inokuchi, K; Niimoto, M; Ogawa, N; Sugimachi, K; Tamada, R1
Anai, H; Fukuchi, K; Kusumoto, H; Kusumoto, T; Maehara, Y; Miyamoto, K; Sugimachi, K1
Ichihashi, H; Kondo, T; Takagi, H; Watanabe, T; Yamauchi, M1
Anai, H; Kusumoto, H; Kusumoto, T; Maehara, Y; Sugimachi, K3
Ichihashi, H; Koike, A; Nakazato, H; Yamamura, Y1
Hirao, Y; Iwata, H; Matsuki, H; Okajima, E; Ozono, S; Sasaki, K; Takahashi, S; Tsunemi, K1
Hattori, T; Jinushi, K; Kim, R; Kirihara, Y; Niimoto, M; Nishiyama, M; Saeki, T; Takagami, S1
Kuroiwa, T; Matsuo, T; Okeda, R; Shibutani, M1
Hashimoto, H; Kanemaru, K; Kuzuhara, S; Nakanishi, T; Ohkoshi, N; Toyokura, Y1
Furuya, A; Kishida, S; Okeda, R; Shiroyama, H; Yano, Y1
Iguchi, T; Ino, Y; Isono, T; Sato, M; Takeda, Y; Takizawa, K; Yokoo, I1
Abe, S; Kamata, H; Kisida, S; Miyagawa, N; Murakami, A; Nagano, H; Ueda, K; Yasui, H1
Takada, K; Tsumura, M; Yoshiga, K1
Kikuchi, M; Uekama, K1
Mishina, H; Okuyama, S1
Ikeda, S; Ito, M; Ninomiya, K; Reshad, K; Taki, T1
Funai, K; Hayahara, N; Kawakita, J; Kishimoto, T; Maekawa, M; Morikawa, Y; Nishijima, T; Nishio, S; Yasumoto, R; Yuki, K1
Hirayama, F; Kikuchi, M; Uekama, K1
Hirota, Y; Hongo, J; Inagaki, M; Ozaki, M; Sawada, M1
Arakawa, H; Inoue, Y; Masamune, O; Nakamura, J; Nasu, H; Sato, M1
Fukunaga, T; Mizoi, Y; Mori, K; Noda, J; Umeda, S1
Abe, S; Akazawa, S; Fujiki, T; Futatsuki, K; Kanda, Y; Kuwatsuru, R; Saifuku, K; Yamamoto, K; Yoon, S; Yoshida, K1
Anai, H; Hiramoto, Y; Kusumoto, H; Kusumoto, T; Maehara, Y; Sugimachi, K1
Taketa, C2
Ichihashi, S; Koike, A; Nakazato, H1
Fukukita, K; Harada, T; Ito, Y; Kubo, M; Sakakura, Y; Yamagiwa, M1
Jinno, H; Ohtaguro, K; Ueda, K; Watanabe, H1
Hatta, M; Hirakawa, T; Kito, T; Kobari, T; Nakazato, H; Yamamura, Y; Yasue, M1
Asakawa, H; Koyama, K; Otake, S; Otawa, H1
Kutsuna, T; Matsumoto, S; Nagai, K; Nomoto, S; Sugimoto, T; Yoshizaki, S1
Hisazumi, H; Kanda, S; Katsumi, T; Kawaguchi, K; Mikawa, I; Misaki, T; Miyagi, T; Nakamura, T; Orito, M; Sakai, A1
Ishijima, B; Mizutani, T; Morimatsu, Y; Sato, J; Yasue, M1
Kinami, Y; Kiriyama, M; Miyazaki, I; Takashima, S; Tomita, F; Ueno, K1
Ezaki, T; Miyagi, N; Nakatani, K; Sakamoto, K; Sugizaki, T1
Akaishi, S; Fukaya, Y; Kakizaki, K; Kato, S; Matsuno, S1
Abe, M; Hirai, K; Kubo, Y; Majima, Y; Ninomiya, F; Sakai, T; Sakemi, T; Sato, K; Shiraishi, K; Tanikawa, K1
Akiharu, W; Fujiwara, M; Higashi, T; Ito, T; Kobayashi, M; Nagashima, H; Nakatsukasa, H; Shiota, T; Yamamoto, H; Yamauchi, Y1
Hino, I; Kimura, I; Kuroda, S; Numoto, A; Ohnoshi, T; Takahashi, M; Tsuji, M; Ueoka, H1
Kishimoto, H; Koga, S; Maeta, M; Masaki, T; Oda, M; Shimizu, N; Tanida, O; Watnabe, S; Yamane, T; Yoshida, Y1
Majima, H; Sueyoshi, K1
Ichijo, M; Kamamoto, Y; Kosakai, H; Nakanishi, A; Noda, T; Shimamoto, I; Shintani, M; Tsujimura, K1
Akazawa, S; Fujiki, T; Futatsuki, K; Honda, T; Izuno, O; Kanda, Y; Nakagawa, T; Sampi, K; Suda, Y1
Karakama, T; Kimura, S; Mitsushima, T; Okeda, R; Toizumi, S; Yokoyama, Y1
Katayama, K; Yoshitake, Y1
Matsui, Y; Okudaira, Y; Sawada, M1
Sakurai, Y1
Hoshi, A; Iigo, M; Kuretani, K; Nakamura, A2
Honda, T1
Hoshi, A; Iigo, M; Kuretani, K1
Koyama, Y2
Chin, F; Hirasawa, H; Isono, K; Kimura, M; Kouzu, T; Okuyama, K; Onoda, S; Ryu, M; Sato, H; Satoh, H; Tounosu, N; Yamamoto, Y1
Hara, Y; Kono, A; Tanaka, M1
Iguro, Y; Kobari, T; Namekawa, H; Ujiie, A1
Hoshi, A; Iigo, M; Kuretani, K; Tokuzen, R1
Imamura, Y; Isoda, T; Koyama, Y; Nakajima, O; Takemasa, Y; Yoshida, Y1
Taguchi, T2
Iida, H; Naganuma, K; Sakurai, Y; Tsukagoshi, S; Tsuruo, T1
Aoyagi, M; Hirashima, T; Hirota, T; Kawachi, T; Matsukura, N; Sugimura, T; Takasugi, T; Uchida, E; Ushio, K; Yoshida, S1
Ando, N; Hoshi, A; Iigo, M; Inomata, M; Kuretani, K; Yoshida, M1
Fort, FL; Kikuchi, Y; Nakamura, M1
Akaishi, S; Furukawa, T; Kobari, M; Matsuno, S; Yamanami, H; Yusa, T1
Abe, R; Enomoto, K; Koyama, H; Kusama, M; Nishi, T; Sonoo, H; Takashima, S; Tominaga, T; Yamaguchi, S; Yoshida, M1
Gröhn, P; Heinonen, E; Helle, L; Numminen, S1
Ikeda, M; Kubo, H; Nakajima, H; Noda, K; Okamura, S; Sugawa, T; Sugimoto, O; Teshima, K; Yamabe, T; Yamagata, S1
Sakuyama, T; Takahashi, N1
Fukuda, I; Hioki, K; Imaoka, S; Kameyama, M; Kikkawa, N; Mori, T; Nakamori, S; Oshima, A; Utsunomiya, J; Yasutomi, M1
Akiyama, S; Asai, S; Ito, K; Kataoka, M; Kawasaki, S; Kondo, K; Sato, T; Satta, T; Takeshima, E; Yamauchi, M1
Hoshino, S; Katsumata, K; Kimura, K; Tani, C; Yamamoto, K; Yamashita, S1
Itsubo, M1
Ito, K; Kato, T; Koike, A; Miura, K; Takagi, H; Yamaguchi, A1
Akiyoshi, T; Kakegawa, T; Maehara, Y; Ogawa, M; Sugimachi, K; Tomita, M1
Fukuda, I; Hioki, K; Iwanaga, T; Kameyama, M; Kanno, H; Kikkawa, N; Mori, T; Ohashi, S; Oshima, A; Utsunomiya, J; Yasutomi, M; Yoden, Y1
Arii, S; Sugahara, K; Tobe, T; Yamamoto, M1
Hori, A; Isogai, M; Kin, Y; Yamaguchi, A; Yamaguchi, R1
Fujisawa, J; Kondo, Y; Miyakawa, K; Nakanishi, Y; Nishimura, A; Oku, T; Osawa, S; Shiroto, H; Uchino, J1
Kuroda, Y; Matsumoto, S; Murakami, M; Nishizawa, S; Noma, S; Sano, A1
Akiba, T; Okeda, R; Tajima, T1
Baba, S; Ishii, M; Ito, K; Kato, T; Matsumoto, S; Miura, K; Takagi, H; Yamaguchi, A1
Eriguchi, M; Fujii, Y; Hasumi, K; Hirose, I; Itoyanagi, H1
Kitamura, K; Maehara, Y; Mori, M; Ohno, S; Sugimachi, K; Tomisaki, S; Tomoda, M1
Inomata, Y; Inoue, K; Kuroda, T; Mizutani, H; Sakuyama, T; Tadaoka, N; Takahashi, N; Yamada, T; Yoshinaga, K1
Hayashi, T; Kohno, H; Nagasue, N; Ono, T; Uchida, M; Yamanoi, A; Yukaya, H1
Hojo, K; Ichihashi, H; Kato, T; Kikuchi, K; Kodaira, S; Kunii, Y; Ogawa, M; Takahashi, T; Tamada, R; Tominaga, T; Yasutomi, M1
Kasai, H; Koike, H; Maeda, M; Maeda, T; Nagawa, H1
Tominaga, T1
Hirata, N; Kitaoka, H; Kitaoka, U; Mabuchi, K; Matsuda, T1
Fukui, H; Kuwano, M; Miyazaki, K; Sato, S; Ueyama, T1
Fukushima, H; Goya, T; Hanaoka, T; Matsuda, M; Sato, K; Tanaka, R1
Eriguchi, M; Fujii, Y; Hasumi, K; Hirai, J; Iwasa, H1
Abe, A; Inada, K; Nakanishi, H; Tatematsu, M; Tsukamoto, T; Yasui, K1
Furuhata, T; Hata, F; Hirata, K; Kawasaki, H; Matsunaga, T; Nakagawa, N; Sasaki, K; Shibata, K; Takasaka, H; Yabana, T; Yasojima, T1
Hyakutake, K; Matsumoto, M; Miyauchi, M; Shishikura, T; Yamamoto, N1
Fukui, H; Miyama, Y; Takeda, H; Tokuda, C1
Furukawa, M; Gomita, S; Kaji, M; Karakama, T; Watanabe, N; Yoshimura, M1
Cho, KH; Choi, SM; Kim, BC; Kim, MK; Lee, SH; Yang, YS1
Kohno, H; Nagasue, N; Nazmy El Assal, O; Ono, T; Yamanoi, A1
Kageyama, T; Tamura, Y; Toizumi, A1
Fujii, H; Kamigaki, T; Kuroda, Y; Nakamura, T; Ohno, M; Tabuchi, Y; Yamagishi, H1
Elomaa, I; Joensuu, H; Osterlund, P; Virkkunen, P1
Higuchi, Y; Muto, T; Nagawa, H; Sawada, T; Sunouchi, K; Tsurita, G; Watanabe, T1
Eriguchi, M; Matsuzawa, A; Nonaka, Y; Takeda, Y; Yanagie, H; Yoshizaki, I1
Asano, T; Danno, M; Fujiwara, J; Kimura, M; Nishi, T; Sano, M; Sasaki, M; Takashima, S; Tominaga, T; Yoshida, K; Yoshida, M1
Osako, Y1
Higashigawa, M; Kagawa, Y; Kakito, H; Kawasaki, H; Kojima, M; Ohkubo, T; Ooi, A; Sakurai, M1
Fujikawa, A; Hachiya, J; Katase, S; Kurosaki, Y; Tsuchiya, K1
Elomaa, I; Joensuu, H; Orpana, A; Osterlund, P; Repo, H1
Ishikawa, H; Iwasaki, Y; Kanazawa, K; Kitajima, M; Kodaira, S; Kotake, K; Koyama, Y; Miyata, M; Nagamachi, Y; Omoto, R; Shida, S; Tajima, Y; Tamakuma, S1
Ito, K; Katoh, H; Kondo, S; Morikawa, T; Okushiba, S1
Burzykowski, T; Buyse, M; Hamada, C; Ohashi, Y; Piedbois, P; Sakamoto, J1
Hioki, K; Hirakawa, K; Imamura, M; Iwanaga, T; Kameyama, M; Kikkawa, N; Monden, M; Nakano, H; Ohhashi, S; Ohtoshi, M; Sakamoto, T; Tanigawa, N; Tomita, N; Yamamura, T; Yasutomi, M1
Hojyo, K; Isomoto, H; Kato, T; Kodaira, S; Kunii, Y; Kunitomo, K; Niimoto, M; Nishida, O; Ohashi, Y; Takahashi, T; Tominaga, T; Watanabe, M; Yasutomi, M1
Koh, M; Morimoto, K1
Abe, R; Aoyama, H; Asaga, T; Awane, H; Danno, M; Ikeda, T; Kimura, M; Koyama, H; Mitsuyama, S; Nishi, T; Ogita, M; Sano, M; Takashima, S; Takatsuka, Y; Toi, M; Tominaga, T; Wada, T; Yoshida, M1
Kodaira, S; Kotake, K; Koyama, Y; Ohashi, Y1
Amano, T; Hiki, Y; Kumada, K; Mitomi, T; Nishiyama, K; Noto, T; Ogawa, N; Oka, H; Oki, S; Otani, Y; Sadahiro, S; Takahashi, T; Takemiya, S; Tsuchiya, S; Yamakawa, T; Yamamura, T1
Hamada, C; Ito, K; Kodaira, S; Nakazato, H; Ohashi, Y; Rahman, M; Sakamoto, J; Yasutomi, M1
Akasu, T1
Babbar, AK; Maitra, A; Sharma, RK; Soni, S1
Aogi, K; Doihara, H; Nishimura, R; Ohsumi, S; Saeki, T; Taira, N; Takashima, S1
Hojo, K; Isomoto, H; Kato, T; Kodaira, S; Kunitomo, K; Ohashi, Y; Takahashi, T; Tominaga, T; Watanabe, M; Yasutomi, M1
Baehring, JM; Fulbright, RK1
Kishida, S; Ota, K1
Mizutani, T2
Hoshino, S; Maekawa, T; Mikami, K; Sakai, T; Shirakusa, T; Yamashita, Y1
Miyazaki, N; Tabata, Y1
Chanchal, A; Maitra, A; Verma, AK1
Haglund, C; Hermunen, K; Osterlund, P1
Armirotti, A; Bandiera, T; Costi, MP; Luciani, R; Pagliuca, C; Piomelli, D; Pizzirani, D; Realini, N; Solorzano, C1
Bhabak, KP; Bhattacherjee, D1
Doki, Y; Fukunaga, M; Ikeda, M; Kato, T; Matsuura, N; Miyake, Y; Mizushima, T; Monden, M; Mori, M; Murata, K; Nakamura, Y; Nezu, R; Noura, S; Ohnishi, T; Ohtsuka, M; Ohue, M; Sekimoto, M; Takemasa, I; Yamamoto, H1
Abercrombie, JJ; Leung, KP; Lopez-Ribot, JL; Ramasubramanian, AK; Srinivasan, A; Torres, NS1
Amaral, AJR; Pasparakis, G; Sanchez-Vazquez, B; Williams, GR; Yu, DG1
Baldwin, WS; Gerard, PD; Reardon, DC; Sengupta, N1
Chechetka, SA; Miyako, E; Pramanik, M; Pu, K; Yu, Y; Zhen, X1
Haglund, C; Hermunen, K; Lantto, E; Österlund, P; Poussa, T1
Barcellos, VA; Fonseca, FL; Joffe, LS; Kmetzsch, L; Reuwsaat, JCV; Rodrigues, ML; Schrank, A; Staats, CC; Vainstein, MH; Zimbres, ACG1
Çömlekçi, E; Kutlu, HM; Vejselova Sezer, C1
Ahn, EE; Dementiev, A; Doan, N; Gelsomino, M; Gorelik, A; Illes, K; Joachimiak, A; Nagar, B; Nguyen, H; Shabani, S1
Chen, Y; Liu, Y; Yao, Y; Zhang, S; Zhu, Y1
Bhat, OM; Hong, J; Huang, D; Li, G; Li, PL; Yuan, X1
Dou, L; Li, H; Mai, Y; Sanchez-Vazquez, B; Trindade, RP; Williams, GR; Zhu, LM; Zou, Q1
Du, X; Duan, Y; Guddat, LW; Hu, T; Jin, Z; Liu, X; Rao, Z; Sun, Y; Wang, H; Wu, Y; Xiao, G; Yang, H; Yang, K; Yang, X; Yu, J; Zhang, B; Zhang, L; Zhao, Y; Zhu, C; Zhu, Y1
Bear, JC; Davies, GL; King, AM; Wells, CJR; Williams, GR; Zhang, Z1
Janostiak, R; Malvi, P; Nagarajan, A; Wajapeyee, N; Zhang, X1
Baldwin, WS; Gessner, EE; Ghent, BN; Shah, MH; van den Hurk, P; Westbrook, NE1
Du, X; Peng, Y; Xing, J; Zhao, C1
Faraji, S; Giudetti, G; Grigorenko, BL; Krylov, AI; Nemukhin, AV; Polyakov, I1

Reviews

14 review(s) available for fluorouracil and carmofur

ArticleYear
[Neurological disorders induced by antineoplastic drugs].
    No to shinkei = Brain and nerve, 1992, Volume: 44, Issue:12

    Topics: Animals; Antineoplastic Agents; Cell Division; Cisplatin; Fluorouracil; Humans; Methotrexate; Nervous System; Nervous System Diseases; Vincristine

1992
Leukoencephalopathy following treatment with carmofur: a case report and review of the Japanese literature.
    Asia-Oceania journal of obstetrics and gynaecology, 1989, Volume: 15, Issue:2

    Topics: Antineoplastic Agents; Brain Diseases; Female; Fluorouracil; Humans; Japan; Middle Aged

1989
Subacute leucoencephalopathy induced by carmofur, a 5-fluorouracil derivative.
    Journal of neurology, 1987, Volume: 234, Issue:6

    Topics: Aged; Antineoplastic Agents; Electroencephalography; Female; Fluorouracil; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Tomography, X-Ray Computed

1987
[Report on an autopsy of a cancer patient with Carmofur (HCFU) leukoencephalopathy].
    Rinsho shinkeigaku = Clinical neurology, 1987, Volume: 27, Issue:11

    Topics: Antineoplastic Agents; Brain; Female; Fluorouracil; Humans; Leukoencephalopathy, Progressive Multifocal; Middle Aged; Tomography, X-Ray Computed

1987
Studies of analogs of fluorinated pyrimidine in Japan.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1981, Volume: 76

    Topics: Animals; Antineoplastic Agents; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fluorouracil; Humans; Japan; Neoplasms; Neoplasms, Experimental; Tegafur; Uracil

1981
[Gastrointestinal cancer and oral anticancer agents].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:3

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents; Camptothecin; Drug Combinations; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Organoplatinum Compounds; Oxonic Acid; Prodrugs; Pyridines; Tegafur; Uracil

1999
[Recent development of oral anti-cancer drugs for breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:3

    Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials, Phase II as Topic; Cyclophosphamide; Drug Administration Schedule; Fadrozole; Female; Floxuridine; Fluorouracil; Gonadotropin-Releasing Hormone; Humans; Medroxyprogesterone Acetate; Survival Rate; Tamoxifen; Toremifene

1999
Adjuvant chemotherapy after resection of hepatocellular carcinoma causes deterioration of long-term prognosis in cirrhotic patients: metaanalysis of three randomized controlled trials.
    Cancer, 2001, Jun-15, Volume: 91, Issue:12

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Administration Schedule; Drug Tolerance; Epirubicin; Female; Fluorouracil; Hepatectomy; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Multivariate Analysis; Neoplasm Recurrence, Local; Prognosis; Survival Rate; Tegafur; Treatment Outcome

2001
Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Feb-01, Volume: 22, Issue:3

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Maximum Tolerated Dose; Mitomycin; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Randomized Controlled Trials as Topic; Rectal Neoplasms; Survival Rate; Tegafur

2004
An individual patient data meta-analysis of adjuvant therapy with carmofur in patients with curatively resected colon cancer.
    Japanese journal of clinical oncology, 2005, Volume: 35, Issue:9

    Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Colonic Neoplasms; Digestive System Surgical Procedures; Disease-Free Survival; Fluorouracil; Humans; Neoplasm Recurrence, Local; Prognosis; Randomized Controlled Trials as Topic; Survival Rate

2005
[Adjuvant chemotherapy for colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Combinations; Evidence-Based Medicine; Fluorouracil; Guidelines as Topic; Humans; Leucovorin; Lymph Node Excision; Neoplasm Staging; Survival Rate; Tegafur; Uracil

2006
[Drug-induced leukoencephalopathy].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2007, Aug-10, Volume: 96, Issue:8

    Topics: Antineoplastic Agents; Brain Edema; Cisplatin; Cytarabine; Fluorouracil; Humans; Hypertensive Encephalopathy; Immunosuppressive Agents; Methotrexate; Nervous System Diseases; Syndrome

2007
[Drug-induced leukoencephalopathy].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Antineoplastic Agents; Antiviral Agents; Fluorouracil; Humans; Immunosuppressive Agents; Interferon-alpha; Methotrexate; Posterior Leukoencephalopathy Syndrome; Time Factors

2007
[Leukoencephalopathy caused by antineoplastic drugs].
    Brain and nerve = Shinkei kenkyu no shinpo, 2008, Volume: 60, Issue:2

    Topics: Antineoplastic Agents; Brain Diseases; Fluorouracil

2008

Trials

41 trial(s) available for fluorouracil and carmofur

ArticleYear
[A comparative clinical study of adjuvant chemotherapy of tumors in the head and neck areas by means of HCFU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Prognosis; Survival Rate

1991
[Oral administration of 1-hexylcarbamoyl-5-fluorouracil (HCFU) in repeated arterial bolus chemotherapy in metastatic liver cancer of humans--preliminary randomized trial].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:8

    Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Prospective Studies

1991
[Mitomycin C plus HCFU adjuvant chemotherapy for noncuratively resected cases of colorectal carcinoma. (Second report): 5-year survival rate. Cooperative Study Group of Kyushu and Chugoku for HCFU Adjuvant Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:3 Pt 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Japan; Mitomycin; Mitomycins; Multicenter Studies as Topic; Prognosis; Prospective Studies; Random Allocation

1989
[Adjuvant chemotherapy for gastric cancer--the third study. First report: central randomization by telephone method and analysis of patients' background factors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:3 Pt 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Drug Administration Schedule; Fluorouracil; Humans; Japan; Mitomycin; Mitomycins; Multicenter Studies as Topic; Picibanil; Random Allocation; Stomach Neoplasms; Tegafur; Telephone

1989
[Outcome of adjuvant mifurol chemotherapy in patients with resected colonic carcinoma].
    Gan no rinsho. Japan journal of cancer clinics, 1989, Volume: 35, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Drug Evaluation; Female; Fluorouracil; Follow-Up Studies; Humans; Japan; Male; Middle Aged; Mitomycin; Mitomycins; Multicenter Studies as Topic; Tegafur

1989
[A randomized controlled trial comparing short-term MF chemotherapy with MF and long-term carmofur chemotherapy as an adjuvant to curative resection of stomach cancer].
    Gan no rinsho. Japan journal of cancer clinics, 1986, Volume: 32, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Administration Schedule; Fluorouracil; Humans; Mitomycin; Mitomycins; Postoperative Period; Prognosis; Random Allocation; Stomach Neoplasms

1986
[Prospective adjuvant chemotherapy, with mitomycin C plus long-term carmofur in colorectal cancer].
    Gan no rinsho. Japan journal of cancer clinics, 1986, Volume: 32, Issue:3

    Topics: Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Drug Evaluation; Fluorouracil; Humans; Mitomycin; Mitomycins; Postoperative Care; Random Allocation; Rectal Neoplasms

1986
[A randomized controlled trial of immunochemotherapy using carmofur (HCFU), mitomycin C and immunopotentiators in advanced gastric cancer following noncurative resection and nonresection].
    Gan no rinsho. Japan journal of cancer clinics, 1986, Volume: 32, Issue:5

    Topics: Adjuvants, Immunologic; Adult; Aged; Clinical Trials as Topic; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Random Allocation; Stomach Neoplasms

1986
Mitomycin C plus carmofur (HCFU) adjuvant chemotherapy for noncuratively resected cases of colorectal carcinoma (interim report).
    The Japanese journal of surgery, 1987, Volume: 17, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Mitomycin; Mitomycins; Prospective Studies; Random Allocation; Rectal Neoplasms

1987
[Prospective adjuvant chemotherapy of mitomycin C plus HCFU for colorectal cancer (2d report)--6-year survival after surgery: Tokai Cooperative Study Group of Surgical Adjuvant Chemotherapy].
    Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:4

    Topics: Adjuvants, Immunologic; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Mitomycin; Mitomycins; Postoperative Care; Rectal Neoplasms

1988
[A randomized controlled trial comparing short-term MF chemotherapy with MF plus long-term HCFU chemotherapy as an adjuvant to a curative resection of stomach cancer: Mifurol Study Group for Stomach Cancer].
    Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:14

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Clinical Trials as Topic; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Mitomycin; Mitomycins; Postoperative Care; Random Allocation; Stomach Neoplasms

1988
[A randomized controlled study to compare 1-hexylcarbamoyl-5-fluorouracil (HCFU) and 1-(2-tetrahydrofuryl)-5-fluorouracil (Tegafur) for the prevention of post-operative recurrence of bladder cancer].
    Hinyokika kiyo. Acta urologica Japonica, 1985, Volume: 31, Issue:7

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Postoperative Period; Random Allocation; Tegafur; Urinary Bladder; Urinary Bladder Neoplasms

1985
[Clinical trial of carmofur (HCFU) in the treatment of malignant ovarian cancer--The first report: combination therapy with endoxan, mitomycin C, and toyomycin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents; Chromomycin A3; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hysterectomy; Mitomycin; Mitomycins; Ovarian Neoplasms

1983
1-Hexylcarbamoyl-5-fluorouracil (HCFU)--a masked 5-fluorinated pyrimidine.
    Cancer treatment reviews, 1981, Volume: 8, Issue:2

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Breast Neoplasms; Cats; Clinical Trials as Topic; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Rabbits; Rats

1981
[Clinical effects of carmofur (Mifurol) on advanced and recurrent breast cancer in a cooperative study. Research association for re-evaluation of direct effects of Mifurol on breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:4

    Topics: Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Agents; Breast Neoplasms; Dizziness; Drug Administration Schedule; Female; Fever; Fluorouracil; Humans; Middle Aged; Nausea; Neoplasm Recurrence, Local; Urination Disorders

1995
Combination of carmofur and interferon-alpha-2B in advanced gastrointestinal cancer--a phase II pilot study.
    Acta oncologica (Stockholm, Sweden), 1994, Volume: 33, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Synergism; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Pilot Projects; Recombinant Proteins; Treatment Outcome

1994
[Long-term administration of carmofur as a post-operative adjuvant chemotherapy for cervical adenocarcinoma. Cervical Adenocarcinoma Cooperative Research Association].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:12

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Middle Aged; Neoplasm Recurrence, Local; Postoperative Period; Registries; Survival Rate; Uterine Cervical Neoplasms

1994
[A comparative clinical study on the treatment of head and neck tumors by adjuvant chemotherapy with HCFU--Second Study by Kinki Head and Neck Tumor Study Group].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Survival Rate

1994
[Some problems of TS measurement after administration of fluoropyrimidines in colorectal cancer. Kinki Cooperative Study Group of Chemotherapy for Colorectal Carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:14

    Topics: Adult; Aged; Antineoplastic Agents; Colorectal Neoplasms; Dipyridamole; Female; Fluorouracil; Humans; Male; Middle Aged; Thymidylate Synthase

1993
Prospective adjuvant therapy with mitomycin C and carmofur (HCFU) for colorectal cancer, 10-year follow-up: Tokai HCFU Study Group, the first study for colorectal cancer.
    Journal of surgical oncology, 1996, Volume: 62, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Japan; Male; Middle Aged; Mitomycin; Prospective Studies; Survival Rate

1996
Postoperative chemotherapy for colorectal cancer by combining 5-fluorouracil infusion and 1-hexylcarbamoyl-5-fluorouracil administration after curative resection.
    Cancer, 1996, Jan-01, Volume: 77, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Postoperative Period; Prospective Studies; Survival Rate

1996
[Comparative study of the combined effect of HCFU and dipyridamole (DP) in colorectal carcinoma--TS inhibition rate. Kinki Cooperative Study Group of Chemotherapy for Colorectal Carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dipyridamole; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunologic Factors; Japan; Male; Middle Aged; Thymidylate Synthase

1996
Adjuvant oral chemotherapy to prevent recurrence after curative resection for hepatocellular carcinoma.
    The British journal of surgery, 1996, Volume: 83, Issue:3

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Disease-Free Survival; Fluorouracil; Humans; Liver Neoplasms; Neoplasm Recurrence, Local; Survival Rate; Time Factors

1996
[Randomized controlled study on adjuvant immunochemotherapy with carmofur (HCFU) for noncuratively resected and unresected gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Chi-Square Distribution; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Humans; Immunotherapy; Japan; Mitomycin; Picibanil; Stomach Neoplasms

1996
Oral adjuvant chemotherapy with carmofur (HCFU) for colorectal cancer: five-year follow-up. Tokai HCFU Study Group--third study on colorectal cancer.
    Journal of surgical oncology, 1996, Volume: 63, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Treatment Outcome

1996
Improved surgical results after combining preoperative hyperthermia with chemotherapy and radiotherapy for patients with carcinoma of the rectum.
    Diseases of the colon and rectum, 1997, Volume: 40, Issue:4

    Topics: Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Hyperthermia, Induced; Male; Middle Aged; Preoperative Care; Prognosis; Radiotherapy, Adjuvant; Rectal Neoplasms; Survival Analysis

1997
Adjuvant chemotherapy with epirubicin and carmofur after radical resection of hepatocellular carcinoma: a prospective randomized study.
    Seminars in oncology, 1997, Volume: 24, Issue:2 Suppl 6

    Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Epirubicin; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Neoplasm Recurrence, Local; Prospective Studies; Survival Rate

1997
[Prospective controlled study on the usefulness of Carmofur as a postoperative adjuvant chemotherapy for colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Mitomycin; Neoplasm Invasiveness; Postoperative Care; Prospective Studies; Rectal Neoplasms; Survival Rate

1997
[Comparative clinical study on 5-FU concentrations for oral HCFU and i.v. 5-FU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:7

    Topics: Administration, Oral; Antineoplastic Agents; Breast Neoplasms; Cross-Over Studies; Drug Administration Schedule; Female; Fluorouracil; Humans; Injections, Intravenous; Survival Rate

2000
Optimal duration of oral adjuvant chemotherapy with Carmofur in the colorectal cancer patients: the Kansai Carmofur Study Group trial III.
    International journal of oncology, 2001, Volume: 19, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Survival Rate; Time Factors; Treatment Outcome

2001
Randomized, controlled trial of lateral node dissection vs. nerve-preserving resection in patients with rectal cancer after preoperative radiotherapy.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Autonomic Nervous System; Disease-Free Survival; Female; Fluorouracil; Humans; Lymph Node Excision; Male; Middle Aged; Preoperative Care; Radiotherapy, Adjuvant; Rectal Neoplasms; Treatment Outcome

2001
Postoperative chemoendocrine therapy for women with node-positive stage II breast cancer with combined cyclophosphamide, tamoxifen, and 1-hexylcarbamoyl-5-fluorouracil.
    The European journal of surgery = Acta chirurgica, 2001, Volume: 167, Issue:8

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Middle Aged; Neoplasm Metastasis; Prospective Studies; Survival Rate; Tamoxifen

2001
[Neo-adjuvant chemotherapy with carmofur for colorectal cancer--a multi-institutional randomized controlled study].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Neoadjuvant Therapy; Neoplasm Staging; Preoperative Care; Prospective Studies; Survival Rate

2002
[Appropriate duration of postoperative oral adjuvant chemotherapy with HCFU for colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:1

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Colonic Neoplasms; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Middle Aged; Postoperative Period; Rectal Neoplasms; Survival Rate

2004
Randomized controlled trial of the efficacy of adjuvant immunochemotherapy and adjuvant chemotherapy for colorectal cancer, using different combinations of the intracutaneous streptococcal preparation OK-432 and the oral pyrimidines 1-hexylcarbamoyl-5-flu
    International journal of clinical oncology, 2004, Volume: 9, Issue:2

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colectomy; Colonic Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Injections, Subcutaneous; Male; Middle Aged; Mitomycin; Neoplasm Staging; Picibanil; Pyrimidines; Radiotherapy, Adjuvant; Rectal Neoplasms; Survival Analysis; Tegafur; Treatment Outcome; Uracil

2004
Postoperative adjuvant use of carmofur for early breast cancer.
    Osaka city medical journal, 2003, Volume: 49, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Carbazilquinone; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Mastectomy; Middle Aged; Neoplasm Staging; Treatment Outcome

2003
1-hexylcarbamoyl-5-fluorouracil + cyclophosphamide + tamoxifen versus CMF + tamoxifen in women with lymph node-positive breast cancer after primary surgery: a randomized controlled trial.
    Oncology reports, 2004, Volume: 12, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Survival Rate; Tamoxifen

2004
A multicenter randomized study comparing 5-fluorouracil continuous infusion (ci) plus 1-hexylcarbamoyl-5-fluorouracil and 5-FU ci alone in colorectal cancer.
    Oncology reports, 2005, Volume: 14, Issue:1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Nausea; Neoplasm Staging; Survival Analysis; Survival Rate; Time Factors; Treatment Outcome; Vomiting

2005
[Multicenter comparative study of the recurrence-inhibitory effect of oral fluoropyrimidine drugs in patients with colorectal cancer following curative resection].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:7

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Leukopenia; Lymphatic Metastasis; Male; Middle Aged; Mitomycin; Rectal Neoplasms; Survival Rate; Tegafur; Uracil

2005
Randomized trial of the efficacy of adjuvant chemotherapy for colon cancer with combination therapy incorporating the oral pyrimidine 1-hexylcarbamoyl-5-fluorouracil.
    Langenbeck's archives of surgery, 2006, Volume: 391, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Combined Modality Therapy; Disease-Free Survival; Fluorouracil; Humans; Liver Neoplasms; Middle Aged; Mitomycin; Neoplasm Staging; Survival Rate; Treatment Outcome

2006
Can carcinoembryonic antigen replace computed tomography in response evaluation of metastatic colorectal cancer?
    Acta oncologica (Stockholm, Sweden), 2018, Volume: 57, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Biomarkers, Tumor; Carcinoembryonic Antigen; Colorectal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Quinazolines; ROC Curve; Sensitivity and Specificity; Thiophenes; Tomography, X-Ray Computed

2018

Other Studies

159 other study(ies) available for fluorouracil and carmofur

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Determination of 1-hexylcarbamoyl-5-fluorouracil and its metabolites in biomedical specimens by high-performance liquid chromatography.
    Journal of chromatography, 1979, May-01, Volume: 163, Issue:1

    Topics: Adult; Antineoplastic Agents; Chromatography, High Pressure Liquid; Female; Fluorouracil; Humans; Male; Neoplasms

1979
Metabolic fate of 1-hexylcarbamoyl-5-fluorouracil in rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 1978, Volume: 8, Issue:9

    Topics: Animals; Biotransformation; Breath Tests; Feces; Fluorouracil; Kidney; Liver; Male; Rats; Tissue Distribution

1978
[A case report of postoperative recurrent hepatocellular carcinoma effectively treated with HCFU administration combined with TAE].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:6

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Combined Modality Therapy; Embolization, Therapeutic; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Postoperative Period

1992
Studies on antitumor effects and mechanism of action of l-hexylcarbamoyl-5-fluorouracil by DNA/BrdU double staining using flow cytometry.
    Human cell, 1992, Volume: 5, Issue:2

    Topics: Antineoplastic Agents; Bromodeoxyuridine; Cell Cycle; DNA; Flow Cytometry; Fluorouracil; Humans; KB Cells; Pharyngeal Neoplasms; Staining and Labeling; Tumor Cells, Cultured

1992
[Serum concentration of HCFU and 5-FU after oral administration of HCFU in postoperative digestive cancer patients].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:11

    Topics: Administration, Oral; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; Gastrectomy; Humans; Stomach Neoplasms

1992
[Signification of liver metastases of colorectal cancer with special reference to recurrence in the residual liver after hepatic resection].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:10 Suppl

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Doxorubicin; Drug Administration Schedule; Fluorouracil; Hepatectomy; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Mitomycin; Neoplasm Recurrence, Local

1992
[Chemosensitivity of head and neck squamous cell carcinomas using subrenal capsule assay--comparative assay of 5-FU, FT, UFT, and HCFU and immunohistochemical study].
    Nihon Jibiinkoka Gakkai kaiho, 1992, Volume: 95, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Fluorouracil; Head and Neck Neoplasms; Immunohistochemistry; Male; Mice; Mice, Inbred C3H; Subrenal Capsule Assay; Tegafur; Uracil

1992
[Study of preventive effect of 1-hexylcarbamoyl-5-fluorouracil (HCFU) or combination of HCFU and 2.5-di-O-acetyl-D-glucaro (1-4) (6-3) dilactone (SLA) after preservative operation against bladder cancer].
    Hinyokika kiyo. Acta urologica Japonica, 1992, Volume: 38, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Combined Modality Therapy; Female; Fluorouracil; Glucaric Acid; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Postoperative Period; Urinary Bladder Neoplasms

1992
[Potentiation of thymidylate synthetase (TS) inhibition by combined administration of HCFU and dipyridamole: preliminary report. Kinki Cooperative Study Group of Chemotherapy for Colorectal Carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dipyridamole; Female; Fluorouracil; Humans; Male; Middle Aged; Pilot Projects; Thymidylate Synthase

1992
[Improvement of stability and bioavailability of 1-hexylcarbamoyl-5-fluorouracil (HCFU) by O-carboxymethyl-O-ethyl-beta- cyclodextrin].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1991, Volume: 111, Issue:10

    Topics: Administration, Oral; Animals; Antineoplastic Agents; beta-Cyclodextrins; Cyclodextrins; Delayed-Action Preparations; Dogs; Drug Carriers; Drug Stability; Fluorouracil; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Absorption; Male; Solubility

1991
Comparative antitumor activity of 5-fluorouracil and its prodrugs in combination with hyperthermia in vitro.
    Acta medica Okayama, 1991, Volume: 45, Issue:5

    Topics: Antineoplastic Agents; Cell Survival; Floxuridine; Fluorouracil; Hot Temperature; Humans; Infant, Newborn; Prodrugs; Tegafur; Tumor Cells, Cultured

1991
Antitumor activity of fluoropyrimidines and thymidylate synthetase inhibition.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:4

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma; Colonic Neoplasms; Enzyme Activation; Fluorouracil; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Stomach Neoplasms; Thymidylate Synthase

1991
Subrenal capsule assay using nude mice as a predictor of the response of the gastric cancer to chemotherapy.
    Journal of surgical oncology, 1991, Volume: 47, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Mitomycins; Neoplasm Transplantation; Stomach Neoplasms; Subrenal Capsule Assay

1991
Adjuvant hepatic intra-arterial chemotherapy after potentially curative hepatectomy for liver metastases from colorectal cancer: a pilot study.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1991, Volume: 17, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitomycin; Neoplasm Recurrence, Local; Pilot Projects; Survival Rate

1991
1-Hexylcarbamoyl-5-fluorouracil alters the expression of heat shock protein in HeLa cells.
    Anti-cancer drugs, 1991, Volume: 2, Issue:1

    Topics: Cells, Cultured; Clone Cells; Fluorouracil; Heat-Shock Proteins; HeLa Cells; Humans; Immunohistochemistry; Stem Cells

1991
Carmofur-induced organic mental disorders.
    The Japanese journal of psychiatry and neurology, 1990, Volume: 44, Issue:4

    Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Electroencephalography; Female; Fluorouracil; Follow-Up Studies; Humans; Leukoencephalopathy, Progressive Multifocal; Lung Neoplasms; Neuropsychological Tests; Substance-Related Disorders; Tomography, X-Ray Computed

1990
[Evaluation of intraperitoneal cancer chemotherapy using an implantable reservoir in patients with peritonitis carcinomatosa].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:8 Pt 2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Cisplatin; Colorectal Neoplasms; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Male; Middle Aged; Mitomycin; Mitomycins; Peritonitis; Prognosis; Stomach Neoplasms; Tegafur

1990
[Chemotherapy with fluoropyrimidines for MOPC-104E plasmacytoma transplanted in mice with CCl4 induced chronic liver dysfunction].
    Nihon Gan Chiryo Gakkai shi, 1990, Mar-20, Volume: 25, Issue:3

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Floxuridine; Fluorouracil; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Plasmacytoma; Tegafur; Uracil

1990
Oral carmofur in advanced gastrointestinal cancer.
    American journal of clinical oncology, 1990, Volume: 13, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms

1990
[Effect of concomitant use of anticancer drugs and a Ca2+ antagonist, on human gastric cancer transplanted into nude mice].
    Nihon Gan Chiryo Gakkai shi, 1990, Jan-20, Volume: 25, Issue:1

    Topics: Animals; Antineoplastic Agents; Drug Combinations; Fluorouracil; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Nicardipine; Stomach Neoplasms; Transplantation, Heterologous

1990
[5-FU concentration in portal blood after oral administration of 1-hexylcarbamoyl-5-fluorouracil (HCFU)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:5

    Topics: Administration, Oral; Antineoplastic Agents; Digestive System Neoplasms; Drug Combinations; Fluorouracil; gamma-Globulins; Humans; Immunotoxins; Melphalan; Portal System

1988
A case of carmofur-induced leukoencephalopathy--MR images and CT findings.
    The Tokai journal of experimental and clinical medicine, 1989, Volume: 14, Issue:4

    Topics: Aged; Antineoplastic Agents; Colonic Neoplasms; Female; Fluorouracil; Humans; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Tomography, X-Ray Computed

1989
Phase II evaluation of peroral carmofur, cyclophosphamide, and hexamethylmelamine as a second-line therapy in advanced epithelial ovarian carcinoma.
    Gynecologic oncology, 1989, Volume: 34, Issue:1

    Topics: Administration, Oral; Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Middle Aged; Ovarian Neoplasms; Prospective Studies

1989
[A case of hepatocellular carcinoma (HCC) with lung metastasis which responded to chemotherapy with a single use of 1-hexylcarbamoyl-5-fluorouracil (HCFU)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:2

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Remission Induction

1989
Low dose 1-hexylcarbamoyl-5-fluorouracil (HCFU) recommended for cirrhotic patients with hepatocellular carcinoma.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:8

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Female; Fluorouracil; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged

1989
[HCFU and 5-fluorouracil levels in the blood and tissue of hepatocellular carcinoma after oral administration of HCFU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:12

    Topics: Administration, Oral; Antineoplastic Agents; Carcinoma, Hepatocellular; Female; Fluorouracil; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Liver Neoplasms; Male; Middle Aged; Tissue Distribution

1989
Application of PHYCON 6600 to achieve sustained release of an antitumor drug (carmofur).
    Drug design and delivery, 1989, Volume: 5, Issue:2

    Topics: Animals; Antineoplastic Agents; Delayed-Action Preparations; Drug Implants; Excipients; Fluorouracil; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Silicone Gels; Silicones

1989
[A case of non-functioning adrenal cortical carcinoma with pulmonary and bony metastases].
    Hinyokika kiyo. Acta urologica Japonica, 1989, Volume: 35, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Antineoplastic Agents; Bone Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Lung Neoplasms; Middle Aged; Mitotane

1989
Hyperthermia enhances the in vitro activity of 1-hexylcarbamoyl-5-fluorouracil compared to that of 5-fluorouracil.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:3

    Topics: Antineoplastic Agents; Combined Modality Therapy; Fluorouracil; HeLa Cells; Humans; Hyperthermia, Induced

1989
[A case of renal cell carcinoma with lung metastases successfully treated by interferon-beta].
    Hinyokika kiyo. Acta urologica Japonica, 1989, Volume: 35, Issue:4

    Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Fluorouracil; Humans; Interferon Type I; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Remission Induction

1989
[Antitumor effects of 5-fluorouracil-bound organic silicon compound].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Ethylamines; Female; Fluorouracil; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Organosilicon Compounds; Pyrimidinones; Sarcoma, Experimental; Transplantation, Heterologous

1989
[1-Hexylcarbamoyl-5-fluorouracil (HCFU) effective in hepatocellular carcinoma metastatic to the lungs--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:10

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms

1987
[5-FU and HCFU concentrations in serum and tissues in hepatocellular carcinoma after HCFU oral administration].
    Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:6

    Topics: Administration, Oral; Carcinoma, Hepatocellular; Fluorouracil; Humans; Liver; Liver Neoplasms

1988
[Release profiles of 5-fluorouracil and its lipophilic derivatives from lipiodol solutions].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:6

    Topics: Fluorouracil; Humans; Hydrogen-Ion Concentration; Infusions, Intra-Arterial; Iodized Oil; Solutions

1988
[Experimental study of anti-tumor agent microcapsules--the effects of embolization and drug releasing].
    Nihon Geka Gakkai zasshi, 1988, Volume: 89, Issue:5

    Topics: Animals; Capsules; Dogs; Embolization, Therapeutic; Fluorouracil; Humans; Iodized Oil; Mice; Peritoneal Neoplasms; Rabbits

1988
[Trans-arterial embolization or transarterial infusion of anti-cancer drugs suspended in a lipid contrast medium against unresectable metastatic liver cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8 Pt 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Embolization, Therapeutic; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Iodized Oil; Liver Neoplasms; Maleic Anhydrides; Mitomycin; Mitomycins; Polystyrenes; Prognosis; Suspensions; Zinostatin

1988
[The determination of thymidylate synthetase inhibition for testing fluoropyrimidines--pharmacokinetics and metabolism of carmofur (HCFU) in patients with gynecologic malignancies--Tokai HCFU Study Group for Gynecologic Malignancies].
    Gan no rinsho. Japan journal of cancer clinics, 1986, Volume: 32, Issue:14

    Topics: Antineoplastic Agents; Female; Floxuridine; Fluorouracil; Genital Neoplasms, Female; Half-Life; Humans; Kinetics; Thymidylate Synthase

1986
[Effects of derivatives of Ara-C, 5-fluorouracil and nitrosourea against intracerebral implanted L1210 leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Cytarabine; Fluorouracil; Leukemia L1210; Mice; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Streptozocin; Tegafur; Uracil

1987
The antiproliferative effects of fluoropyrimidine derivatives against human tumor xenografts in a subrenal capsule assay.
    The Japanese journal of surgery, 1988, Volume: 18, Issue:6

    Topics: Animals; Antineoplastic Agents; Body Weight; Cell Division; Colorectal Neoplasms; Floxuridine; Fluorouracil; Humans; Male; Mice; Mice, Nude; Stomach Neoplasms; Subrenal Capsule Assay; Tegafur; Transplantation, Heterologous

1988
[A clinical study of radiotherapy with HCFU for advanced and recurrent breast cancers. Radiation and HCFU Study Group for breast cancer].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:2

    Topics: Adenocarcinoma, Scirrhous; Adult; Aged; Breast Neoplasms; Carcinoma; Combined Modality Therapy; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Middle Aged; Radiotherapy Dosage

1985
[Experimental chemotherapy of ovarian cancers heterotransplanted in nude mice].
    Nihon Sanka Fujinka Gakkai zasshi, 1985, Volume: 37, Issue:8

    Topics: Adenocarcinoma, Mucinous; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Recurrence, Local; Ovarian Neoplasms; Teratoma

1985
[One-shot therapy and transcatheter arterial embolization (TAE) therapy of unresectable hepatocellular carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Doxorubicin; Embolization, Therapeutic; Female; Fluorouracil; Hepatic Artery; Humans; Injections, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins

1985
[Blood level of 5-fluorouracil (5-FU) by oral administration of 1-hexylcarbamoyl-5-fluorouracil (HCFU) and tegafur in patients with hepatocellular carcinoma].
    Nihon Gan Chiryo Gakkai shi, 1985, Oct-20, Volume: 20, Issue:9

    Topics: Administration, Oral; Adult; Antineoplastic Agents; Carcinoma, Hepatocellular; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Tegafur

1985
Reversible leukoencephalopathy caused by 5-fluorouracil derivatives, presenting as akinetic mutism.
    Surgical neurology, 1986, Volume: 25, Issue:3

    Topics: Anal Gland Neoplasms; Animals; Breast Neoplasms; Carcinoma; Female; Fluorouracil; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Movement Disorders; Mutism; Tegafur; Tomography, X-Ray Computed

1986
[Combined effects of radiation and 5-FU derivatives].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:3 Pt 1

    Topics: Adenocarcinoma; Animals; Cell Division; Fluorouracil; Male; Mice; Radiotherapy Dosage; Tegafur

1986
[Chemosensitivity testing for 5-FU and 5-FU derivatives using subrenal capsule assay].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:3 Pt 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colony-Forming Units Assay; Fluorouracil; Humans; Lung Neoplasms; Stomach Neoplasms; Tegafur; Tumor Stem Cell Assay; Uracil

1987
[Human colorectal carcinoma is more sensitive to HCFU than 5-FU and tegafur in in vitro and in vivo drug sensitivity tests].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:2

    Topics: Animals; Colonic Neoplasms; Fluorouracil; Humans; Mice; Rectal Neoplasms; Subrenal Capsule Assay; Tegafur; Tumor Cells, Cultured

1988
Colorectal carcinoma in vitro is more sensitive to 1-hexylcarbamoyl-5-fluorouracil compared with six other antitumor drugs: carboquone, Adriamycin, mitomycin C, aclacinomycin A, cisplatin, 5-fluorouracil.
    Diseases of the colon and rectum, 1988, Volume: 31, Issue:1

    Topics: Aclarubicin; Antineoplastic Agents; Carbazilquinone; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Humans; In Vitro Techniques; Mitomycin; Mitomycins; Naphthacenes; Rectal Neoplasms; Succinate Dehydrogenase

1988
Sensitivity test for 5-fluorouracil and its analogues, 1-(2-tetrahydrofuryl)-5-fluorouracil, uracil/1-(2-tetrahydrofuryl)-5-fluorouracil (4:1) and 1-hexylcarbamoyl-5-fluorouracil, using the subrenal capsule assay.
    Oncology, 1988, Volume: 45, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Resistance; Fluorouracil; Gastrointestinal Neoplasms; Humans; Kidney; Male; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Subrenal Capsule Assay; Tegafur; Uracil

1988
UFT is more antineoplastic against gastric carcinoma than 5-fluorouracil, 1-(2-tetrahydrofuryl)-5-fluorouracil and 1-hexylcarbamoyl-5-fluorouracil.
    Chemotherapy, 1988, Volume: 34, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Male; Mice; Stomach Neoplasms; Subrenal Capsule Assay; Tegafur; Uracil

1988
Effect of 1-hexylcarbamoyl-5-fluorouracil on development of rat urinary bladder tumor induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.
    The Japanese journal of experimental medicine, 1988, Volume: 58, Issue:3

    Topics: Animals; Antineoplastic Agents; Body Weight; Butylhydroxybutylnitrosamine; Fluorouracil; Male; Nitrosamines; Organ Size; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms

1988
[Inhibition of thymidylate synthetase and antiproliferative effect by 1-hexylcarbamoyl-5-fluorouracil].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:11

    Topics: Animals; Antineoplastic Agents; Cell Division; Esophageal Neoplasms; Fluorouracil; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Stomach Neoplasms; Thymidylate Synthase

1988
Subacute neurotoxicity of 5-fluorouracil and its derivative, carmofur, in cats.
    Acta pathologica japonica, 1988, Volume: 38, Issue:10

    Topics: Animals; Behavior, Animal; Cats; Cerebellum; Female; Fluorouracil; Male; Microscopy, Electron; Neurons; Neurotoxins

1988
[Estimation of 1-hexylcarbamoyl-5-fluorouracil (HCFU) and 5-FU concentrations in sera and resected specimens from patients with ovarian tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:4 Pt 1

    Topics: Administration, Oral; Female; Fluorouracil; Humans; Ovarian Neoplasms; Ovariectomy; Ovary; Uterus

1988
[A case of leukoencephalopathy caused by HCFU].
    Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:6

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Diseases; Cisplatin; Combined Modality Therapy; Electroencephalography; Female; Fluorouracil; Granulosa Cell Tumor; Humans; Hysterectomy; Neoplasms, Multiple Primary; Ovarian Neoplasms; Ovariectomy; Teratoma

1988
Enhancement of antitumor effects of 1-hexylcarbamoyl-5-fluorouracil combined with hyperthermia on Ehrlich ascites tumor in vivo and Nakahara-Fukuoka sarcoma cell in vitro.
    Cancer research, 1988, Jul-15, Volume: 48, Issue:14

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cell Survival; Combined Modality Therapy; Fluorouracil; Hyperthermia, Induced; Mice; Neoplasm Transplantation; Sarcoma, Experimental; Tumor Cells, Cultured

1988
[Effect of dimethyl beta-cyclodextrin on oral or rectal absorption of 1-hexylcarbamoyl-5-fluorouracil (HCFU)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1988, Volume: 108, Issue:2

    Topics: Administration, Oral; Administration, Rectal; Animals; Antineoplastic Agents; beta-Cyclodextrins; Cyclodextrins; Dextrins; Fluorouracil; Male; Rabbits; Starch

1988
Principia of cancer therapy. XIX. Effects of per rectum carmofur on radiotherapeutic efficacy of rectal carcinomas.
    The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku, 1987, Volume: 34, Issue:1-4

    Topics: Carcinoembryonic Antigen; Carcinoma; Fluorouracil; Humans; Metabolic Clearance Rate; Rectal Neoplasms; Suppositories

1987
[Studies on the pleural permeability of carmofur].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:4

    Topics: Administration, Oral; Fluorouracil; Humans; Neoplasms; Permeability; Pleural Effusion

1987
[Study on effectiveness of carmofur (Mifurol) in urogenital carcinoma, especially bladder cancer, as a post-operative adjuvant chemotherapeutic agent].
    Hinyokika kiyo. Acta urologica Japonica, 1987, Volume: 33, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Postoperative Period; Prognosis; Urinary Bladder Neoplasms

1987
Improvement of chemical instability of carmoful in beta-cyclodextrin solid complex by utilizing some organic acids.
    Chemical & pharmaceutical bulletin, 1987, Volume: 35, Issue:1

    Topics: beta-Cyclodextrins; Chemical Phenomena; Chemistry; Cyclodextrins; Drug Stability; Fluorouracil

1987
[Effect of post operative maintenance chemotherapy against ovarian cancer].
    Nihon Sanka Fujinka Gakkai zasshi, 1987, Volume: 39, Issue:7

    Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Humans; Mice; Mice, Nude; Neoplasm Recurrence, Local; Neoplasm Transplantation; Ovarian Neoplasms; Teratoma

1987
[A case of esophageal cancer of superficial depressive type in an advanced age successfully treated with HCFU].
    Nihon Gan Chiryo Gakkai shi, 1987, May-20, Volume: 22, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Esophageal Neoplasms; Fluorouracil; Humans; Male

1987
Disulfiram-like reaction associated with carmofur after celiac plexus alcohol block.
    Anesthesiology, 1987, Volume: 67, Issue:5

    Topics: Aged; Alcohol Deterrents; Antineoplastic Agents; Autonomic Nerve Block; Celiac Plexus; Ethanol; Fluorouracil; Humans; Male

1987
[A case of recurrent gastric cancer successfully treated with a combination of cisplatin and carmofur].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:11

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Stomach Neoplasms

1987
1-Hexylcarbamoyl-5-fluorouracil is more cytostatic than 5-fluorouracil against human tumors in vitro.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:10

    Topics: Antineoplastic Agents; Cell Survival; Fluorouracil; HeLa Cells; Humans; Neoplasms; Succinate Dehydrogenase; Tumor Cells, Cultured

1987
[Clinical effect of HCFU therapy of head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:5

    Topics: Administration, Oral; Antineoplastic Agents; Drug Administration Schedule; Drug Evaluation; Fluorouracil; Head and Neck Neoplasms; Humans

1986
[Clinical study of HCFU and radiation therapy in head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:6

    Topics: Antineoplastic Agents; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Radiotherapy Dosage

1986
[The dose finding of adjuvant carmofur chemotherapy in patients with stomach cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:6

    Topics: Drug Administration Schedule; Fluorouracil; Humans; Stomach Neoplasms

1986
[Clinical study of HCFU in combination with irradiation therapy in squamous cell carcinoma of the head and neck].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:8

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Radiotherapy Dosage

1986
[Central nervous system toxicity of carmofur, an antineoplastic drug].
    No to shinkei = Brain and nerve, 1986, Volume: 38, Issue:12

    Topics: Aged; Central Nervous System Diseases; Electroencephalography; Female; Fluorouracil; Humans; Male; Tomography, X-Ray Computed

1986
[Combination effects of CDDP, ACR and HCFU on progressive urothelial tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:6

    Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Humans; Kidney Neoplasms; Kidney Pelvis; Male; Middle Aged; Naphthacenes; Ureteral Neoplasms; Urinary Bladder Neoplasms; Urologic Neoplasms

1985
[Influence of immunopotentiators on the activation of 5-FU derivatives].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Biological Products; Cytochrome P-450 Enzyme System; Fluorouracil; In Vitro Techniques; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Picibanil; Proteoglycans; Rats; Rats, Inbred Strains; Tegafur

1985
[Evaluation of combined radiotherapy of gastric carcinoma].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Middle Aged; Prognosis; Radiotherapy, High-Energy; Stomach Neoplasms; Tegafur

1985
[Comparison of the concentration of HCFU, tegafur and 5-FU in the thoracic duct lymph after oral administration of HCFU and tegafur].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:8

    Topics: Administration, Oral; Female; Fluorouracil; Humans; Lymph; Middle Aged; Tegafur; Thoracic Duct

1985
[A case of toxic leucoencephalopathy induced by 5FU derivatives].
    No shinkei geka. Neurological surgery, 1985, Volume: 13, Issue:11

    Topics: Antineoplastic Agents; Brain; Brain Diseases; Breast Neoplasms; Female; Fluorouracil; Humans; Middle Aged; Tegafur

1985
[Distribution of 1-hexycarbamoyl-5-fluorouracil in rats and human patients, and clinical results in patients with colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:3 Pt 1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Rats; Rats, Inbred Strains; Rectal Neoplasms

1986
[Effects of combination therapy of carmofur and nicardipine of human gastric cancer in nude mice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:4

    Topics: Animals; Cell Line; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nicardipine; Nifedipine; Stomach Neoplasms

1985
[Effects of urokinase on the transfer of 1-hexylcarbamoyl-5-fluorouracil (HCFU) into the blood, bile and pancreatic juice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:11

    Topics: Administration, Oral; Antineoplastic Agents; Bile; Fluorouracil; Humans; Pancreatic Juice; Pancreatic Neoplasms; Urokinase-Type Plasminogen Activator

1985
[Clinical evaluation of 1-hexylcarbamoyl-5-fluorouracil (HCFU) in hepatocellular carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:11

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Speech Disorders; Unconsciousness

1984
[Role of oral administration of 1-hexyl-carbamoyl-5-fluorouracil (HCFU) for multimodal treatment of inoperable cirrhotics with hepatocellular carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:12 Pt 1

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Embolization, Therapeutic; Female; Fluorouracil; Hepatic Artery; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Picibanil; Prognosis

1984
[Intraarterial Adriamycin for patients with hepatocellular carcinoma and metastatic liver carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:12 Pt 1

    Topics: Adult; Aged; Alkaline Phosphatase; Carcinoma, Hepatocellular; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Injections, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Stomach Neoplasms

1984
[Combination chemotherapy with neocarzinostatin(NCS), HCFU and picibanil(NHO therapy) for advanced carcinoma of the digestive system--a comparative study with NF, and NFO therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Digestive System Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Picibanil; Zinostatin

1984
[Cerebrospinal fluid distributions of systemically administered fluorinated pyrimidines].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Ependymoma; Female; Fluorouracil; Glioblastoma; Humans; Male; Middle Aged; Tegafur

1983
[Combination chemotherapy of CIS-diamminedichloroplatinum (II) and fluoropyrimidine derivatives for advanced gastric cancer: a preliminary report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms; Tegafur

1984
Neuropathologic study on chronic neurotoxicity of 5-fluorouracil and its masked compounds in dogs.
    Acta neuropathologica, 1984, Volume: 63, Issue:4

    Topics: Animals; Axons; Brain; Dogs; Female; Fluorouracil; Male; Microscopy, Electron; Myelin Sheath; Neuroglia; Neurons; Tegafur; Vacuoles

1984
[Blood concentration of HCFU in gastrectomized patients].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:8

    Topics: Fluorouracil; Gastrectomy; Humans; Postoperative Period; Stomach Neoplasms

1984
Concentrations of a new antitumor agent, 1-hexylcarbamoyl-5-fluorouracil in serum and gynecologic tumor tissue.
    Nihon Sanka Fujinka Gakkai zasshi, 1983, Volume: 35, Issue:12

    Topics: Antineoplastic Agents; Female; Fluorouracil; Humans; Ovarian Neoplasms; Uterine Cervical Neoplasms

1983
Excretion of 1-hexylcarbamoyl-5-fluorouracil in urine of mice.
    Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:7

    Topics: Animals; beta-Alanine; Female; Fluorouracil; Mice; Mice, Inbred Strains

1981
[Clinical study of HCFU and radiation therapy for head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Maxillary Sinus; Middle Aged; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms

1983
Metabolic fate on 1-hexylcarbamoyl-5-fluorouracil and 5-fluorouracil in mice bearing ascites sarcoma 180.
    Journal of the National Cancer Institute, 1981, Volume: 66, Issue:2

    Topics: Administration, Oral; Animals; Ascitic Fluid; Female; Fluorouracil; Kinetics; Mice; Sarcoma 180

1981
[Evaluation of the therapeutic effect of HCFU (1-hexylcarbamoyl-5-fluorouracil) on non-resectable stomach cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms

1982
[Evaluation of the optimum method of administration of a new antineoplastic agent, HCFU, based on the serum 5-FU concentration following oral administration].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:2

    Topics: Administration, Oral; Antineoplastic Agents; Fluorouracil; Humans

1982
[Phase II study of carmofur (HCFU) fine granules].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Child; Child, Preschool; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Stomach Neoplasms

1982
Metabolism of 1-hexylcarbamoyl-5-fluorouracil (HCFU), a new antitumour agent, in rats, rabbits and dogs.
    Xenobiotica; the fate of foreign compounds in biological systems, 1981, Volume: 11, Issue:1

    Topics: Absorption; Animals; Antineoplastic Agents; Dogs; Fluorouracil; Kinetics; Male; Oxidation-Reduction; Rabbits; Rats; Species Specificity

1981
Effect of 1-hexylcarbamoyl-5-fluorouracil on spontaneous mammary adenocarcinoma of mice.
    Gan, 1980, Volume: 71, Issue:5

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Drug Administration Schedule; Female; Fluorouracil; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice

1980
Quantitative determination of 1-hexylcarbamoyl-5-fluorouracil and its metabolites in man.
    Journal of chromatography, 1981, Sep-11, Volume: 225, Issue:1

    Topics: Chromatography, High Pressure Liquid; Fluorouracil; Humans; Time Factors

1981
Review of a new antimetabolic agent 1-hexylcarbamoyl-5-fluorouracil (HCFU).
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1980, Volume: 70

    Topics: Aged; Animals; Drug Evaluation; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Male; Mice; Middle Aged; Neoplasms; Neoplasms, Experimental; Rats

1980
Determination of two new metabolites of 1-hexylcarbamoyl-5-fluorouracil in biomedical specimens by high-performance liquid chromatography.
    Journal of chromatography, 1980, Apr-11, Volume: 182, Issue:1

    Topics: Adult; Antineoplastic Agents; Body Fluids; Chromatography, High Pressure Liquid; Fluorouracil; Humans; Kinetics; Male

1980
Inhibition of murine colon adenocarcinomas and Lewis lung carcinoma by 1-hexylcarbamoyl-5-fluorouracil.
    Cancer chemotherapy and pharmacology, 1980, Volume: 4, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; In Vitro Techniques; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental

1980
Chemotherapeutic study on canine gastric cancer induced by N-ethyl-N'-nitro-N-nitrosoguanidine.
    Gan, 1980, Volume: 71, Issue:3

    Topics: Adenocarcinoma; Animals; Dogs; Fluorouracil; Humans; Male; Methylnitronitrosoguanidine; Stomach Neoplasms

1980
Antitumor activity of metabolites of 1-hexylcarbamoyl-5-fluorouracil and related compounds against L1210 leukemia in vivo and L5178Y lymphoma cells in vitro.
    Journal of pharmacobio-dynamics, 1980, Volume: 3, Issue:9

    Topics: Animals; Antineoplastic Agents; Cells, Cultured; Fluorouracil; Leukemia L1210; Leukemia L5178; Male; Mice

1980
Metabolic fate of 1-hexylcarbamoyl-5-fluorouracil after oral administration in mice.
    Xenobiotica; the fate of foreign compounds in biological systems, 1980, Volume: 10, Issue:11

    Topics: Administration, Oral; Animals; Female; Fluorouracil; Intestine, Small; Kidney; Liver; Lung; Mice

1980
Fetal liver micronucleus assay in mice of 5-fluorouracil and related compounds.
    Mutation research, 1993, Volume: 291, Issue:1

    Topics: Animals; Bone Marrow; Dose-Response Relationship, Drug; Female; Fetus; Fluorouracil; Liver; Male; Mice; Mice, Inbred C3H; Micronucleus Tests; Tegafur

1993
[Transfer of carmofur (HCFU) to the serum, bile, pancreatic juice and pancreatic tumor tissue in the cases of peri-pancreatic head cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:5

    Topics: Administration, Oral; Antineoplastic Agents; Bile; Biliary Tract Neoplasms; Fluorouracil; Humans; Pancreatic Juice; Pancreatic Neoplasms

1995
[TS inhibition rate and flow cytometric analysis of DNA content in preoperative chemotherapy with biochemical modulator].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21 Suppl 1

    Topics: Administration, Oral; Adult; Aged; Chemotherapy, Adjuvant; Colorectal Neoplasms; Dipyridamole; DNA, Neoplasm; Female; Flow Cytometry; Fluorouracil; Humans; Male; Middle Aged; Preoperative Care; Thymidylate Synthase

1994
[In vitro effect of 1-hexylcarbamoyl-5-fluorouracil on human cancer cell lines of gastrointestinal tract].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:14

    Topics: Antineoplastic Agents; Fluorouracil; Gastrointestinal Neoplasms; Humans; Tumor Cells, Cultured

1993
[Evaluation of neoadjuvant combination chemotherapy with pirarubicin, carmofur and tamoxifen citrate on outpatients with advanced and recurrence breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:2

    Topics: Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Doxorubicin; Female; Fluorouracil; Humans; Middle Aged; Neoplasm Recurrence, Local; Outpatients; Tamoxifen; Treatment Outcome

1994
[The present status of chemotherapy for hepatocellular carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:7

    Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Doxorubicin; Drug Delivery Systems; Fluorouracil; Humans; Infusion Pumps; Infusions, Intra-Arterial; Liver Neoplasms; Mitomycin; Survival Rate; Tegafur; Uracil

1993
[Study on the combined preoperative treatment with CDDP and HCFU for gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; Male; Middle Aged; Preoperative Care; Stomach Neoplasms; Thymidylate Synthase

1996
Carmofur-induced leukoencephalopathy: MRI.
    Neuroradiology, 1995, Volume: 37, Issue:8

    Topics: Antineoplastic Agents; Brain; Brain Damage, Chronic; Breast Neoplasms; Chemotherapy, Adjuvant; Demyelinating Diseases; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Middle Aged; Neurologic Examination

1995
Metabolites of 5-fluorouracil, alpha-fluoro-beta-alanine and fluoroacetic acid, directly injure myelinated fibers in tissue culture.
    Acta neuropathologica, 1996, Volume: 92, Issue:1

    Topics: Animals; Animals, Newborn; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cerebellum; Culture Techniques; Fluorouracil; Immunohistochemistry; Mice; Mice, Inbred ICR; Microscopy, Phase-Contrast; Nerve Fibers, Myelinated; Tegafur

1996
[Characterization of spontaneous liver metastatic model of BALB/c retroperitoneal sarcoma (LMFS) injected in footpad and antitumor effects of HCFU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:3

    Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Fluorouracil; Liver; Liver Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Organ Size; Retroperitoneal Neoplasms; Sarcoma, Experimental; Tumor Cells, Cultured

1997
[A case of recurrent gastric cancer with liver metastasis responding to combination chemotherapy with cisplatin and carmofur].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Fluorouracil; Humans; Liver Neoplasms; Lymphatic Metastasis; Male; Stomach Neoplasms

1997
Alcohol consumption enhances liver metastasis in colorectal carcinoma patients.
    Cancer, 1998, Oct-15, Volume: 83, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Analysis of Variance; Antineoplastic Agents; Blood Vessels; Carcinoma; Chemotherapy, Adjuvant; Colonic Neoplasms; Ethanol; Female; Fluorouracil; Follow-Up Studies; gamma-Glutamyltransferase; Humans; Intestinal Mucosa; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Invasiveness; Neoplasm Staging; Rectal Neoplasms; Risk Factors

1998
[A case of multiple liver metastases showing good response by administration of carmofur alone in an aged patient with colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Liver Neoplasms

1999
[Anti-tumor effects of carmofur on human 5-FU resistant cells].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:11

    Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Mice; Mice, Nude; Tumor Cells, Cultured

1999
[Successful endocrine chemotherapy in patients with multiple bone metastases of breast cancer--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Humans; Medroxyprogesterone; Middle Aged; Tamoxifen

1999
[Effects of HCFU and TNP 470 on liver metastasis of BALB/c retroperitoneal sarcoma (LMFS)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:13

    Topics: Angiogenesis Inhibitors; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cyclohexanes; Female; Fluorouracil; Liver Neoplasms; Mice; Mice, Inbred BALB C; O-(Chloroacetylcarbamoyl)fumagillol; Retroperitoneal Neoplasms; Sarcoma, Experimental; Sesquiterpenes; Tumor Cells, Cultured

1999
Induction of apoptosis in metastatic foci from human gastric cancer xenografts in nude mice and reduction of circulating tumor cells in blood by 5-FU and 1-hexylcarbamoyl-5-fluorouracil.
    Journal of cancer research and clinical oncology, 1999, Volume: 125, Issue:12

    Topics: Animals; Antigens, Nuclear; Antineoplastic Agents; Apoptosis; Cell Division; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Ki-67 Antigen; Lung; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Metastasis; Nuclear Proteins; Stomach Neoplasms; Time Factors; Transplantation, Heterologous

1999
[Weekly low-dose CPT-11 and HCFU for advanced colorectal cancer on an outpatient treatment basis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:6

    Topics: Adenocarcinoma; Administration, Oral; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Lymph Node Excision; Lymphatic Metastasis

2000
[Antitumor activity of 1-hexylcarbamoyluracil which is carmofur substituted fluorine for hydrogen].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:7

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Female; Fluorouracil; Mice; Mice, Inbred BALB C; Stomach Neoplasms; Tumor Cells, Cultured; Uracil

2000
Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 16). Effects of short-term administration of carmofur on spermatogenesis.
    The Journal of toxicological sciences, 2000, Volume: 25 Spec No

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Epididymis; Fluorouracil; Longevity; Male; Organ Size; Rats; Rats, Sprague-Dawley; Seminiferous Epithelium; Spermatogenesis; Testis; Time Factors; Toxicity Tests

2000
5-fluorouracil-induced leukoencephalopathy in patients with breast cancer.
    Journal of Korean medical science, 2001, Volume: 16, Issue:3

    Topics: Adenocarcinoma, Mucinous; Adult; Anti-Inflammatory Agents; Antineoplastic Agents; Brain; Breast Neoplasms; Carcinoma, Ductal, Breast; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Glucocorticoids; Humans; Magnetic Resonance Imaging; Methylprednisolone; Middle Aged; Nervous System Diseases; Prednisolone; Radiography

2001
[Inhibition of HCFU absorption after resection for gastric cancer--application of hydroxyaluminium gel].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:6

    Topics: Adult; Aged; Aluminum Hydroxide; Antineoplastic Agents; Chemotherapy, Adjuvant; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Female; Fluorouracil; Gastrectomy; Humans; Magnesium Hydroxide; Male; Middle Aged; Patient Compliance; Stomach Neoplasms

2001
A phase I study of raltitrexed (Tomudex) combined with carmofur in metastatic colorectal cancer.
    Oncology, 2001, Volume: 61, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Gastrointestinal Diseases; Hematologic Diseases; Humans; Male; Maximum Tolerated Dose; Middle Aged; Nervous System Diseases; Quinazolines; Salvage Therapy; Thiophenes; Treatment Outcome

2001
Docetaxel alone or orally combined with 5-fluorouracil and its derivatives: effects on mouse mammary tumor cell line MM2 in vitro and in vivo.
    Anti-cancer drugs, 2001, Volume: 12, Issue:8

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Docetaxel; Drug Synergism; Female; Floxuridine; Fluorouracil; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Paclitaxel; Prodrugs; Taxoids; Thymidine Phosphorylase; Tumor Cells, Cultured; Up-Regulation

2001
[A case of reversible carmofur-induced leukoencephalopathy].
    No to shinkei = Brain and nerve, 2001, Volume: 53, Issue:10

    Topics: Adult; Antineoplastic Agents; Brain; Brain Diseases; Breast Neoplasms; Female; Fluorouracil; Humans; Magnetic Resonance Imaging

2001
Plasma, intestine and tumor levels of 5-fluorouracil in mice bearing L1210 ascites tumor following oral administration of 5-fluorouracil, UFT (mixed compound of tegafur and uracil), carmofur and 5'-deoxy-5-fluorouridine.
    Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Drug Combinations; Floxuridine; Fluorouracil; Intestinal Mucosa; Leukemia L1210; Male; Mice; Tegafur; Uracil

2001
Diffusion-weighted MR imaging of Carmofur-induced leukoencephalopathy.
    European radiology, 2001, Volume: 11, Issue:12

    Topics: Adult; Antineoplastic Agents; Brain; Brain Diseases; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Diffusion; Encephalomalacia; Female; Fluorouracil; Humans; Image Enhancement; Magnetic Resonance Imaging; Male; Middle Aged; Sigmoid Neoplasms

2001
Raltitrexed treatment promotes systemic inflammatory reaction in patients with colorectal carcinoma.
    British journal of cancer, 2002, Sep-09, Volume: 87, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; C-Reactive Protein; Colorectal Neoplasms; Cross-Sectional Studies; Fatigue; Female; Fever; Fluorouracil; Humans; Inflammation; Interleukin-6; Liver Neoplasms; Longitudinal Studies; Lung Neoplasms; Male; Middle Aged; Quinazolines; Thiophenes; Thymidylate Synthase; Tumor Necrosis Factor-alpha

2002
[Analysis of microsatellite instability and p53 LOH in advanced colorectal cancers--first report of the No. 3 protocol].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Genes, p53; Humans; Loss of Heterozygosity; Male; Microsatellite Repeats; Prognosis; Rectal Neoplasms

2004
Delivery of hydrophobised 5-fluorouracil derivative to brain tissue through intravenous route using surface modified nanogels.
    Journal of drug targeting, 2006, Volume: 14, Issue:2

    Topics: Animals; Autoradiography; Brain; Drug Compounding; Drug Delivery Systems; Excipients; Female; Fluorouracil; Gels; Injections, Intravenous; Light; Male; Nanostructures; Particle Size; Polysorbates; Prodrugs; Rabbits; Radiopharmaceuticals; Scattering, Radiation; Technetium; Tissue Distribution

2006
S-1 (TS-1) maintained complete response for approximately 10 years in a case of metastatic breast cancer.
    Breast cancer (Tokyo, Japan), 2006, Volume: 13, Issue:2

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Immunohistochemistry; Lung Neoplasms; Mastectomy, Modified Radical; Middle Aged; Neoplasm Staging; Remission Induction; Risk Assessment; Tamoxifen; Tegafur; Time Factors; Treatment Outcome

2006
Delayed leukoencephalopathy with stroke-like presentation in chemotherapy recipients.
    Journal of neurology, neurosurgery, and psychiatry, 2008, Volume: 79, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Brain; Brain Edema; Capecitabine; Dementia, Vascular; Deoxycytidine; Diffusion Magnetic Resonance Imaging; Energy Metabolism; Female; Fluorouracil; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Infusions, Intravenous; Injections, Spinal; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neoplasms; Nerve Fibers, Myelinated; Neurologic Examination; Registries; Remission, Spontaneous; Stroke; Tegafur

2008
Immunochemotherapy with PSK and fluoropyrimidines improves long-term prognosis for curatively resected colorectal cancer.
    Cancer biotherapy & radiopharmaceuticals, 2008, Volume: 23, Issue:4

    Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Combined Modality Therapy; Drug Combinations; Female; Floxuridine; Fluorouracil; Humans; Immunotherapy; Kaplan-Meier Estimate; Male; Middle Aged; Prognosis; Proportional Hazards Models; Proteoglycans; Retrospective Studies; Tegafur; Uracil

2008
Anti-tumor activity of carmofur water-solubilized by lactic acid oligomer-grafted pullulan nanogels.
    Journal of nanoscience and nanotechnology, 2009, Volume: 9, Issue:8

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Dimethyl Sulfoxide; Drug Screening Assays, Antitumor; Fluorouracil; Glucans; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Nanostructures; Solubility

2009
Co-polymeric hydrophilic nanospheres for drug delivery: release kinetics, and cellular uptake.
    Indian journal of experimental biology, 2010, Volume: 48, Issue:10

    Topics: Acrylamides; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Fluorouracil; Humans; Hydrophobic and Hydrophilic Interactions; Nanospheres; Polymers; Povidone

2010
CEA fluctuation during a single fluorouracil-based chemotherapy cycle for metastatic colorectal cancer.
    Anticancer research, 2013, Volume: 33, Issue:1

    Topics: Adult; Aged; Biomarkers, Tumor; Carcinoembryonic Antigen; Colorectal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Quinazolines; Thiophenes; Tomography, X-Ray Computed

2013
Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity.
    Scientific reports, 2013, Volume: 3

    Topics: Acid Ceramidase; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Ceramides; Drug Resistance, Multiple; Fluorouracil; Humans; Male; Mice; Neoplasms

2013
Atom based 3D-QSAR studies on 2,4-dioxopyrimidine-1-carboxamide analogs: Validation of experimental inhibitory potencies towards acid ceramidase.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2016, Feb-15, Volume: 83

    Topics: Acid Ceramidase; Fluorouracil; Humans; Models, Molecular; Quantitative Structure-Activity Relationship

2016
Micrometastasis Volume in Lymph Nodes Determines Disease Recurrence Rate of Stage II Colorectal Cancer: A Prospective Multicenter Trial.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2016, 07-01, Volume: 22, Issue:13

    Topics: Aged; Antineoplastic Agents; Biomarkers, Tumor; Carcinoembryonic Antigen; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Lymph Nodes; Male; Middle Aged; Neoplasm Micrometastasis; Neoplasm Recurrence, Local; Prospective Studies; RNA, Messenger

2016
Screening a Commercial Library of Pharmacologically Active Small Molecules against Staphylococcus aureus Biofilms.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:10

    Topics: Anti-Bacterial Agents; Auranofin; Biofilms; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Repositioning; Fluorouracil; High-Throughput Screening Assays; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Niclosamide; Small Molecule Libraries; Staphylococcus aureus

2016
Electrosprayed Janus Particles for Combined Photo-Chemotherapy.
    AAPS PharmSciTech, 2017, Volume: 18, Issue:5

    Topics: A549 Cells; Antineoplastic Agents; Fluorouracil; Humans; Particle Size; Pharmaceutic Aids; Photochemotherapy; Photosensitizing Agents; Povidone; Rose Bengal

2017
Exchange of polar lipids from adults to neonates in Daphnia magna: Perturbations in sphingomyelin allocation by dietary lipids and environmental toxicants.
    PloS one, 2017, Volume: 12, Issue:5

    Topics: Animals; Atrazine; Daphnia; Dietary Fats; Fatty Acids, Unsaturated; Fertility; Fluorouracil; Gene Expression Regulation; Lipid Metabolism; Phosphatidylcholines; Sphingomyelins; Triclosan; Water Pollutants, Chemical

2017
Light-driven liquid metal nanotransformers for biomedical theranostics.
    Nature communications, 2017, 05-31, Volume: 8

    Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Drug Liberation; Female; Fluorouracil; HeLa Cells; Humans; Infrared Rays; Lasers; Materials Testing; Metal Nanoparticles; Mice; Microfluidics; Models, Animal; Nanocapsules; Radiographic Image Enhancement; Radiography; Reactive Oxygen Species; Theranostic Nanomedicine

2017
Pharmacological inhibition of pigmentation in Cryptococcus.
    FEMS yeast research, 2019, 01-01, Volume: 19, Issue:1

    Topics: Antifungal Agents; Cryptococcus gattii; DNA Mutational Analysis; Drug Evaluation, Preclinical; Flucytosine; Fluorouracil; Genetic Testing; Melanins; Mutagenesis, Insertional

2019
Toward stimulating apoptosis in human lung adenocarcinoma cells by novel nano-carmofur compound treatment.
    Anti-cancer drugs, 2021, 06-01, Volume: 32, Issue:6

    Topics: A549 Cells; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Fluorouracil; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Nanoparticles

2021
Molecular Mechanism of Inhibition of Acid Ceramidase by Carmofur.
    Journal of medicinal chemistry, 2019, 01-24, Volume: 62, Issue:2

    Topics: Acid Ceramidase; Antineoplastic Agents; Binding Sites; Crystallography, X-Ray; Fluorouracil; Humans; Molecular Dynamics Simulation; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins

2019
Facile Transfer of Reverse Micelles from the Organic to the Aqueous Phase for Mimicking Enzyme Catalysis and Imaging-Guided Cancer Therapy.
    Langmuir : the ACS journal of surfaces and colloids, 2019, 04-30, Volume: 35, Issue:17

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; A549 Cells; Antineoplastic Agents; Benzoin; Catalysis; Drug Carriers; Drug Liberation; Fluorescent Dyes; Fluorouracil; Gold; Humans; Metal Nanoparticles; Micelles; Neoplasms; Oxidation-Reduction; Rhodamines; Water

2019
Control of lysosomal TRPML1 channel activity and exosome release by acid ceramidase in mouse podocytes.
    American journal of physiology. Cell physiology, 2019, 09-01, Volume: 317, Issue:3

    Topics: Acid Ceramidase; Animals; Cell Line, Transformed; Exosomes; Fluorouracil; Lysosomes; Mice; Mice, Inbred C57BL; Podocytes; Transient Receptor Potential Channels

2019
Electrospun oral formulations for combined photo-chemotherapy of colon cancer.
    Colloids and surfaces. B, Biointerfaces, 2019, Nov-01, Volume: 183

    Topics: Acrylic Resins; Administration, Oral; Animals; Antineoplastic Agents; Caco-2 Cells; Cell Line; Cell Survival; Drug Carriers; Drug Combinations; Electrochemical Techniques; Fibroblasts; Fluorouracil; Humans; Hypromellose Derivatives; Intestine, Large; Light; Nanofibers; Organ Specificity; Photosensitizing Agents; Phototherapy; Rats, Sprague-Dawley; Rose Bengal; Tissue Culture Techniques

2019
Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur.
    Nature structural & molecular biology, 2020, Volume: 27, Issue:6

    Topics: Animals; Betacoronavirus; Chlorocebus aethiops; Coronavirus 3C Proteases; Coronavirus Infections; COVID-19; Cysteine Endopeptidases; Fluorouracil; Models, Molecular; Pandemics; Pneumonia, Viral; SARS-CoV-2; Vero Cells; Viral Nonstructural Proteins

2020
pH-Responsive nanocomposite fibres allowing MRI monitoring of drug release.
    Journal of materials chemistry. B, 2020, 08-19, Volume: 8, Issue:32

    Topics: Drug Carriers; Drug Liberation; Ferric Compounds; Fluorouracil; Hydrogen-Ion Concentration; Magnetic Resonance Imaging; Nanocomposites

2020
N-acylsphingosine amidohydrolase 1 promotes melanoma growth and metastasis by suppressing peroxisome biogenesis-induced ROS production.
    Molecular metabolism, 2021, Volume: 48

    Topics: Acid Ceramidase; Animals; Carcinogenesis; Cell Line, Tumor; Ceramides; E2F1 Transcription Factor; Fluorouracil; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; MAP Kinase Signaling System; Melanoma; Mice, Nude; Neoplasm Metastasis; Peroxisomes; Reactive Oxygen Species; Skin Neoplasms; Transfection; Tumor Burden; Xenograft Model Antitumor Assays

2021
The reproductive effects of the cancer chemotherapy agent, Carmofur, on Daphnia magna are mediated by its metabolite, 5-Fluorouracil.
    Ecotoxicology (London, England), 2022, Volume: 31, Issue:5

    Topics: Animals; Antineoplastic Agents; Daphnia; Fluorouracil; Neoplasms; Reproduction

2022
Temperature/pH-responsive carmofur-loaded nanogels rapidly prepared via one-pot laser-induced emulsion polymerization.
    Colloids and surfaces. B, Biointerfaces, 2022, Volume: 217

    Topics: Drug Carriers; Emulsions; Fluorouracil; Hydrogen-Ion Concentration; Lasers; Nanogels; Polymerization; Temperature

2022
How Reproducible Are QM/MM Simulations? Lessons from Computational Studies of the Covalent Inhibition of the SARS-CoV-2 Main Protease by Carmofur.
    Journal of chemical theory and computation, 2022, Aug-09, Volume: 18, Issue:8

    Topics: Coronavirus 3C Proteases; COVID-19; Fluorouracil; Humans; Quantum Theory; Reproducibility of Results; SARS-CoV-2

2022