fluorouracil has been researched along with carmofur in 214 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 101 (47.20) | 18.7374 |
| 1990's | 54 (25.23) | 18.2507 |
| 2000's | 37 (17.29) | 29.6817 |
| 2010's | 15 (7.01) | 24.3611 |
| 2020's | 7 (3.27) | 2.80 |
| Authors | Studies |
|---|---|
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Eguchi, S; Hara, Y; Kono, A; Matsushima, Y; Tanaka, M | 2 |
| Kobari, T; Kobayashi, H; Kumakura, M; Miyama, Y; Namekawa, H; Shirakawa, I; Tan, K; Ujiie, A; Watanabe, S; Yamamoto, H | 1 |
| Kuzuhara, S | 2 |
| Imai, Y; Ito, J; Kobayashi, K; Okamoto, M; Tagawa, K; Taniguchi, M; Tanzawa, Y; Toda, N; Unuma, T; Uta, Y | 1 |
| Hasegawa, N; Kawamoto, K; Uemura, T | 1 |
| Kuroda, Y; Ohkuma, R; Ohsato, K | 1 |
| Amano, H; Awano, T; Funami, Y; Koide, Y; Matsubara, H; Matsushita, K; Nakaichi, H; Ochiai, T; Okuyama, K; Tohnosu, N | 1 |
| Kusumoto, T; Miyagi, M; Nakashima, T | 1 |
| Hayahara, N; Horii, A; Kashihara, N; Kawakita, J; Kishimoto, T; Maekawa, M; Morikawa, Y; Nishijima, T; Wada, S; Yasumoto, R | 1 |
| Fukuda, I; Hioki, K; Iwanaga, T; Kameyama, M; Kato, T; Kikkawa, N; Mori, T; Utsunomiya, J; Yasutomi, M | 1 |
| Kozuka, T; Matsunaga, T; Matsuoka, H; Miyaguchi, M; Nakai, Y; Nishimura, T; Sakai, S; Sato, T; Tanabe, M; Yoshino, K | 2 |
| Hirayama, F; Horiuchi, Y; Uekama, K | 1 |
| Akazai, Y; Fuchimoto, S; Iwagaki, H; Matsubara, N; Orita, K; Shiiki, S; Watanabe, T | 1 |
| Abe, O; Arisawa, Y; Fujita, S; Ishibiki, K; Josui, K; Kodaira, S; Kubota, T; Mabuchi, K; Suto, A; Yamamoto, T | 1 |
| Akiyama, S; Ito, A; Ito, K; Kondo, K; Satta, T; Takagi, H; Watanabe, T; Yamauchi, M | 1 |
| Chang, YC; Kohno, H; Nagasue, N; Nakamura, T; Ogawa, Y; Sasaki, K; Takahashi, M; Yukaya, H | 1 |
| Hojo, K; Makuuchi, M; Moriya, Y; Sugihara, K | 1 |
| Emi, Y; Kohnoe, S; Kusumoto, T; Maehara, Y; Sakaguchi, Y; Sugimachi, K | 1 |
| Hori, M; Koizumi, J; Shiraishi, H; Suzuki, T; Uchida, K | 1 |
| Katsuki, Y; Nishimura, A; Tsuji, Y; Yasuda, T | 1 |
| Imai, S; Morimoto, H; Nio, Y; Shiraishi, T; Tobe, T; Tseng, CC; Tsubono, M | 1 |
| Gröhn, P; Heinonen, E; Kumpulainen, E; Länsimies, H; Lantto, A; Numminen, S; Pyrhönen, S; Salmi, R | 1 |
| Nakano, H; Nakatani, K; Nishiwada, T; Okumura, T; Sawada, H; Shino, Y; Watanabe, A; Yamada, Y; Yano, T | 1 |
| Furusawa, M; Hara, Y; Kameda, K; Nakane, H; Nohtsuka, T; Saeki, K; Seo, Y; Sonoda, T; Tomoda, H; Tsujitani, S | 1 |
| Aoki, Y; Fujita, H; Saitoh, H; Shinohara, Y; Takagi, S | 1 |
| Abe, O; Hattori, T; Kikuchi, K; Komi, N; Kondo, T; Kunii, Y; Nakajima, T; Nakazato, H; Taguchi, T; Tanabe, T | 1 |
| Gröhn, P; Heinonen, E; Kivinen, S; Sipilä, P; Vesala, J | 1 |
| Kimura, T; Kusama, S; Morioka, Y; Muto, T; Ogawa, N; Tomiyama, J | 1 |
| Akazawa, S; Fujiki, T; Futatsugi, K; Kanda, Y; Muraoka, M; Nakajima, T; Naoi, Y; Saifuku, K; Suzuki, F; Yamamoto, K | 1 |
| Kanematsu, T; Shimada, M; Sugimachi, K; Takenaka, K | 1 |
| Hamazaki, K; Mimura, H; Mori, M; Orita, K | 1 |
| Azuma, T; Imasaka, K; Nagai, T; Ueda, H | 1 |
| Katsumi, T; Murayama, K | 1 |
| Masui, Y; Okamura, S; Okazaki, T; Sugimoto, O; Sugino, M; Ueki, M; Ushiroyama, T; Yamada, T; Yamazaki, H; Yanagawa, Y | 1 |
| Kusumoto, T; Maehara, Y; Sakaguchi, Y; Sugimachi, K | 1 |
| Horie, M; Kawada, Y; Kobayashi, S; Komeda, H; Kuriyama, M; Takahashi, Y; Yamada, S | 1 |
| Fukushima, K | 1 |
| Higashi, H; Kanematsu, T; Matsumata, T; Sugimachi, K; Takenaka, K; Yoshida, Y | 1 |
| Suenaga, M | 1 |
| Kanazawa, A; Kawaguchi, T; Machida, R; Nagai, T; Takayama, K | 1 |
| Takahashi, M | 1 |
| Itoh, A; Kitai, S; Sawai, K; Seiki, K; Shimamura, Y; Shimotsuma, M; Shioaki, Y; Takahashi, T; Taniguchi, H; Yamaguchi, T | 1 |
| Hori, M; Kano, T; Mizuno, K; Nishida, Y; Ohta, M; Okamoto, E; Sakakibara, K; Tokuhashi, Y; Tomita, Y; Yoshio, G | 1 |
| Kato, T; Ota, K | 1 |
| Hattori, T; Hirabayashi, N; Kirihara, Y; Niimoto, M; Nishiyama, M; Nosoh, Y; Saeki, T; Takagami, S | 1 |
| Amino, S; Ebata, K; Hashimoto, S; Horiuchi, J; Ikeda, M; Kaneda, K; Matsuda, T; Mikuriya, S; Okawa, T | 1 |
| Sawada, M | 1 |
| Abe, M; Hirai, K; Kawazoe, Y; Kumagai, M; Tanikawa, K; Yamashita, K | 1 |
| Fuse, M; Kondo, H; Mori, K; Ohta, Y; Onji, M; Yamashita, Y | 1 |
| Aoki, N | 1 |
| Dokiya, T; Hashimoto, S; Kunieda, E; Miyamoto, H; Shigematsu, N; Tominaga, J | 1 |
| Ichihashi, H; Koike, A; Nakazato, H | 1 |
| Ichihashi, H; Imaizumi, M; Kondo, T; Takagi, H; Terabe, K; Watanabe, T; Yamauchi, M | 1 |
| Nakanishi, Y | 1 |
| Anai, H; Kusumoto, H; Maehara, Y; Masuda, H; Sugimachi, K | 1 |
| Hattori, T; Inokuchi, K; Niimoto, M; Ogawa, N; Sugimachi, K; Tamada, R | 1 |
| Anai, H; Fukuchi, K; Kusumoto, H; Kusumoto, T; Maehara, Y; Miyamoto, K; Sugimachi, K | 1 |
| Ichihashi, H; Kondo, T; Takagi, H; Watanabe, T; Yamauchi, M | 1 |
| Anai, H; Kusumoto, H; Kusumoto, T; Maehara, Y; Sugimachi, K | 3 |
| Ichihashi, H; Koike, A; Nakazato, H; Yamamura, Y | 1 |
| Hirao, Y; Iwata, H; Matsuki, H; Okajima, E; Ozono, S; Sasaki, K; Takahashi, S; Tsunemi, K | 1 |
| Hattori, T; Jinushi, K; Kim, R; Kirihara, Y; Niimoto, M; Nishiyama, M; Saeki, T; Takagami, S | 1 |
| Kuroiwa, T; Matsuo, T; Okeda, R; Shibutani, M | 1 |
| Hashimoto, H; Kanemaru, K; Kuzuhara, S; Nakanishi, T; Ohkoshi, N; Toyokura, Y | 1 |
| Furuya, A; Kishida, S; Okeda, R; Shiroyama, H; Yano, Y | 1 |
| Iguchi, T; Ino, Y; Isono, T; Sato, M; Takeda, Y; Takizawa, K; Yokoo, I | 1 |
| Abe, S; Kamata, H; Kisida, S; Miyagawa, N; Murakami, A; Nagano, H; Ueda, K; Yasui, H | 1 |
| Takada, K; Tsumura, M; Yoshiga, K | 1 |
| Kikuchi, M; Uekama, K | 1 |
| Mishina, H; Okuyama, S | 1 |
| Ikeda, S; Ito, M; Ninomiya, K; Reshad, K; Taki, T | 1 |
| Funai, K; Hayahara, N; Kawakita, J; Kishimoto, T; Maekawa, M; Morikawa, Y; Nishijima, T; Nishio, S; Yasumoto, R; Yuki, K | 1 |
| Hirayama, F; Kikuchi, M; Uekama, K | 1 |
| Hirota, Y; Hongo, J; Inagaki, M; Ozaki, M; Sawada, M | 1 |
| Arakawa, H; Inoue, Y; Masamune, O; Nakamura, J; Nasu, H; Sato, M | 1 |
| Fukunaga, T; Mizoi, Y; Mori, K; Noda, J; Umeda, S | 1 |
| Abe, S; Akazawa, S; Fujiki, T; Futatsuki, K; Kanda, Y; Kuwatsuru, R; Saifuku, K; Yamamoto, K; Yoon, S; Yoshida, K | 1 |
| Anai, H; Hiramoto, Y; Kusumoto, H; Kusumoto, T; Maehara, Y; Sugimachi, K | 1 |
| Taketa, C | 2 |
| Ichihashi, S; Koike, A; Nakazato, H | 1 |
| Fukukita, K; Harada, T; Ito, Y; Kubo, M; Sakakura, Y; Yamagiwa, M | 1 |
| Jinno, H; Ohtaguro, K; Ueda, K; Watanabe, H | 1 |
| Hatta, M; Hirakawa, T; Kito, T; Kobari, T; Nakazato, H; Yamamura, Y; Yasue, M | 1 |
| Asakawa, H; Koyama, K; Otake, S; Otawa, H | 1 |
| Kutsuna, T; Matsumoto, S; Nagai, K; Nomoto, S; Sugimoto, T; Yoshizaki, S | 1 |
| Hisazumi, H; Kanda, S; Katsumi, T; Kawaguchi, K; Mikawa, I; Misaki, T; Miyagi, T; Nakamura, T; Orito, M; Sakai, A | 1 |
| Ishijima, B; Mizutani, T; Morimatsu, Y; Sato, J; Yasue, M | 1 |
| Kinami, Y; Kiriyama, M; Miyazaki, I; Takashima, S; Tomita, F; Ueno, K | 1 |
| Ezaki, T; Miyagi, N; Nakatani, K; Sakamoto, K; Sugizaki, T | 1 |
| Akaishi, S; Fukaya, Y; Kakizaki, K; Kato, S; Matsuno, S | 1 |
| Abe, M; Hirai, K; Kubo, Y; Majima, Y; Ninomiya, F; Sakai, T; Sakemi, T; Sato, K; Shiraishi, K; Tanikawa, K | 1 |
| Akiharu, W; Fujiwara, M; Higashi, T; Ito, T; Kobayashi, M; Nagashima, H; Nakatsukasa, H; Shiota, T; Yamamoto, H; Yamauchi, Y | 1 |
| Hino, I; Kimura, I; Kuroda, S; Numoto, A; Ohnoshi, T; Takahashi, M; Tsuji, M; Ueoka, H | 1 |
| Kishimoto, H; Koga, S; Maeta, M; Masaki, T; Oda, M; Shimizu, N; Tanida, O; Watnabe, S; Yamane, T; Yoshida, Y | 1 |
| Majima, H; Sueyoshi, K | 1 |
| Ichijo, M; Kamamoto, Y; Kosakai, H; Nakanishi, A; Noda, T; Shimamoto, I; Shintani, M; Tsujimura, K | 1 |
| Akazawa, S; Fujiki, T; Futatsuki, K; Honda, T; Izuno, O; Kanda, Y; Nakagawa, T; Sampi, K; Suda, Y | 1 |
| Karakama, T; Kimura, S; Mitsushima, T; Okeda, R; Toizumi, S; Yokoyama, Y | 1 |
| Katayama, K; Yoshitake, Y | 1 |
| Matsui, Y; Okudaira, Y; Sawada, M | 1 |
| Sakurai, Y | 1 |
| Hoshi, A; Iigo, M; Kuretani, K; Nakamura, A | 2 |
| Honda, T | 1 |
| Hoshi, A; Iigo, M; Kuretani, K | 1 |
| Koyama, Y | 2 |
| Chin, F; Hirasawa, H; Isono, K; Kimura, M; Kouzu, T; Okuyama, K; Onoda, S; Ryu, M; Sato, H; Satoh, H; Tounosu, N; Yamamoto, Y | 1 |
| Hara, Y; Kono, A; Tanaka, M | 1 |
| Iguro, Y; Kobari, T; Namekawa, H; Ujiie, A | 1 |
| Hoshi, A; Iigo, M; Kuretani, K; Tokuzen, R | 1 |
| Imamura, Y; Isoda, T; Koyama, Y; Nakajima, O; Takemasa, Y; Yoshida, Y | 1 |
| Taguchi, T | 2 |
| Iida, H; Naganuma, K; Sakurai, Y; Tsukagoshi, S; Tsuruo, T | 1 |
| Aoyagi, M; Hirashima, T; Hirota, T; Kawachi, T; Matsukura, N; Sugimura, T; Takasugi, T; Uchida, E; Ushio, K; Yoshida, S | 1 |
| Ando, N; Hoshi, A; Iigo, M; Inomata, M; Kuretani, K; Yoshida, M | 1 |
| Fort, FL; Kikuchi, Y; Nakamura, M | 1 |
| Akaishi, S; Furukawa, T; Kobari, M; Matsuno, S; Yamanami, H; Yusa, T | 1 |
| Abe, R; Enomoto, K; Koyama, H; Kusama, M; Nishi, T; Sonoo, H; Takashima, S; Tominaga, T; Yamaguchi, S; Yoshida, M | 1 |
| Gröhn, P; Heinonen, E; Helle, L; Numminen, S | 1 |
| Ikeda, M; Kubo, H; Nakajima, H; Noda, K; Okamura, S; Sugawa, T; Sugimoto, O; Teshima, K; Yamabe, T; Yamagata, S | 1 |
| Sakuyama, T; Takahashi, N | 1 |
| Fukuda, I; Hioki, K; Imaoka, S; Kameyama, M; Kikkawa, N; Mori, T; Nakamori, S; Oshima, A; Utsunomiya, J; Yasutomi, M | 1 |
| Akiyama, S; Asai, S; Ito, K; Kataoka, M; Kawasaki, S; Kondo, K; Sato, T; Satta, T; Takeshima, E; Yamauchi, M | 1 |
| Hoshino, S; Katsumata, K; Kimura, K; Tani, C; Yamamoto, K; Yamashita, S | 1 |
| Itsubo, M | 1 |
| Ito, K; Kato, T; Koike, A; Miura, K; Takagi, H; Yamaguchi, A | 1 |
| Akiyoshi, T; Kakegawa, T; Maehara, Y; Ogawa, M; Sugimachi, K; Tomita, M | 1 |
| Fukuda, I; Hioki, K; Iwanaga, T; Kameyama, M; Kanno, H; Kikkawa, N; Mori, T; Ohashi, S; Oshima, A; Utsunomiya, J; Yasutomi, M; Yoden, Y | 1 |
| Arii, S; Sugahara, K; Tobe, T; Yamamoto, M | 1 |
| Hori, A; Isogai, M; Kin, Y; Yamaguchi, A; Yamaguchi, R | 1 |
| Fujisawa, J; Kondo, Y; Miyakawa, K; Nakanishi, Y; Nishimura, A; Oku, T; Osawa, S; Shiroto, H; Uchino, J | 1 |
| Kuroda, Y; Matsumoto, S; Murakami, M; Nishizawa, S; Noma, S; Sano, A | 1 |
| Akiba, T; Okeda, R; Tajima, T | 1 |
| Baba, S; Ishii, M; Ito, K; Kato, T; Matsumoto, S; Miura, K; Takagi, H; Yamaguchi, A | 1 |
| Eriguchi, M; Fujii, Y; Hasumi, K; Hirose, I; Itoyanagi, H | 1 |
| Kitamura, K; Maehara, Y; Mori, M; Ohno, S; Sugimachi, K; Tomisaki, S; Tomoda, M | 1 |
| Inomata, Y; Inoue, K; Kuroda, T; Mizutani, H; Sakuyama, T; Tadaoka, N; Takahashi, N; Yamada, T; Yoshinaga, K | 1 |
| Hayashi, T; Kohno, H; Nagasue, N; Ono, T; Uchida, M; Yamanoi, A; Yukaya, H | 1 |
| Hojo, K; Ichihashi, H; Kato, T; Kikuchi, K; Kodaira, S; Kunii, Y; Ogawa, M; Takahashi, T; Tamada, R; Tominaga, T; Yasutomi, M | 1 |
| Kasai, H; Koike, H; Maeda, M; Maeda, T; Nagawa, H | 1 |
| Tominaga, T | 1 |
| Hirata, N; Kitaoka, H; Kitaoka, U; Mabuchi, K; Matsuda, T | 1 |
| Fukui, H; Kuwano, M; Miyazaki, K; Sato, S; Ueyama, T | 1 |
| Fukushima, H; Goya, T; Hanaoka, T; Matsuda, M; Sato, K; Tanaka, R | 1 |
| Eriguchi, M; Fujii, Y; Hasumi, K; Hirai, J; Iwasa, H | 1 |
| Abe, A; Inada, K; Nakanishi, H; Tatematsu, M; Tsukamoto, T; Yasui, K | 1 |
| Furuhata, T; Hata, F; Hirata, K; Kawasaki, H; Matsunaga, T; Nakagawa, N; Sasaki, K; Shibata, K; Takasaka, H; Yabana, T; Yasojima, T | 1 |
| Hyakutake, K; Matsumoto, M; Miyauchi, M; Shishikura, T; Yamamoto, N | 1 |
| Fukui, H; Miyama, Y; Takeda, H; Tokuda, C | 1 |
| Furukawa, M; Gomita, S; Kaji, M; Karakama, T; Watanabe, N; Yoshimura, M | 1 |
| Cho, KH; Choi, SM; Kim, BC; Kim, MK; Lee, SH; Yang, YS | 1 |
| Kohno, H; Nagasue, N; Nazmy El Assal, O; Ono, T; Yamanoi, A | 1 |
| Kageyama, T; Tamura, Y; Toizumi, A | 1 |
| Fujii, H; Kamigaki, T; Kuroda, Y; Nakamura, T; Ohno, M; Tabuchi, Y; Yamagishi, H | 1 |
| Elomaa, I; Joensuu, H; Osterlund, P; Virkkunen, P | 1 |
| Higuchi, Y; Muto, T; Nagawa, H; Sawada, T; Sunouchi, K; Tsurita, G; Watanabe, T | 1 |
| Eriguchi, M; Matsuzawa, A; Nonaka, Y; Takeda, Y; Yanagie, H; Yoshizaki, I | 1 |
| Asano, T; Danno, M; Fujiwara, J; Kimura, M; Nishi, T; Sano, M; Sasaki, M; Takashima, S; Tominaga, T; Yoshida, K; Yoshida, M | 1 |
| Osako, Y | 1 |
| Higashigawa, M; Kagawa, Y; Kakito, H; Kawasaki, H; Kojima, M; Ohkubo, T; Ooi, A; Sakurai, M | 1 |
| Fujikawa, A; Hachiya, J; Katase, S; Kurosaki, Y; Tsuchiya, K | 1 |
| Elomaa, I; Joensuu, H; Orpana, A; Osterlund, P; Repo, H | 1 |
| Ishikawa, H; Iwasaki, Y; Kanazawa, K; Kitajima, M; Kodaira, S; Kotake, K; Koyama, Y; Miyata, M; Nagamachi, Y; Omoto, R; Shida, S; Tajima, Y; Tamakuma, S | 1 |
| Ito, K; Katoh, H; Kondo, S; Morikawa, T; Okushiba, S | 1 |
| Burzykowski, T; Buyse, M; Hamada, C; Ohashi, Y; Piedbois, P; Sakamoto, J | 1 |
| Hioki, K; Hirakawa, K; Imamura, M; Iwanaga, T; Kameyama, M; Kikkawa, N; Monden, M; Nakano, H; Ohhashi, S; Ohtoshi, M; Sakamoto, T; Tanigawa, N; Tomita, N; Yamamura, T; Yasutomi, M | 1 |
| Hojyo, K; Isomoto, H; Kato, T; Kodaira, S; Kunii, Y; Kunitomo, K; Niimoto, M; Nishida, O; Ohashi, Y; Takahashi, T; Tominaga, T; Watanabe, M; Yasutomi, M | 1 |
| Koh, M; Morimoto, K | 1 |
| Abe, R; Aoyama, H; Asaga, T; Awane, H; Danno, M; Ikeda, T; Kimura, M; Koyama, H; Mitsuyama, S; Nishi, T; Ogita, M; Sano, M; Takashima, S; Takatsuka, Y; Toi, M; Tominaga, T; Wada, T; Yoshida, M | 1 |
| Kodaira, S; Kotake, K; Koyama, Y; Ohashi, Y | 1 |
| Amano, T; Hiki, Y; Kumada, K; Mitomi, T; Nishiyama, K; Noto, T; Ogawa, N; Oka, H; Oki, S; Otani, Y; Sadahiro, S; Takahashi, T; Takemiya, S; Tsuchiya, S; Yamakawa, T; Yamamura, T | 1 |
| Hamada, C; Ito, K; Kodaira, S; Nakazato, H; Ohashi, Y; Rahman, M; Sakamoto, J; Yasutomi, M | 1 |
| Akasu, T | 1 |
| Babbar, AK; Maitra, A; Sharma, RK; Soni, S | 1 |
| Aogi, K; Doihara, H; Nishimura, R; Ohsumi, S; Saeki, T; Taira, N; Takashima, S | 1 |
| Hojo, K; Isomoto, H; Kato, T; Kodaira, S; Kunitomo, K; Ohashi, Y; Takahashi, T; Tominaga, T; Watanabe, M; Yasutomi, M | 1 |
| Baehring, JM; Fulbright, RK | 1 |
| Kishida, S; Ota, K | 1 |
| Mizutani, T | 2 |
| Hoshino, S; Maekawa, T; Mikami, K; Sakai, T; Shirakusa, T; Yamashita, Y | 1 |
| Miyazaki, N; Tabata, Y | 1 |
| Chanchal, A; Maitra, A; Verma, AK | 1 |
| Haglund, C; Hermunen, K; Osterlund, P | 1 |
| Armirotti, A; Bandiera, T; Costi, MP; Luciani, R; Pagliuca, C; Piomelli, D; Pizzirani, D; Realini, N; Solorzano, C | 1 |
| Bhabak, KP; Bhattacherjee, D | 1 |
| Doki, Y; Fukunaga, M; Ikeda, M; Kato, T; Matsuura, N; Miyake, Y; Mizushima, T; Monden, M; Mori, M; Murata, K; Nakamura, Y; Nezu, R; Noura, S; Ohnishi, T; Ohtsuka, M; Ohue, M; Sekimoto, M; Takemasa, I; Yamamoto, H | 1 |
| Abercrombie, JJ; Leung, KP; Lopez-Ribot, JL; Ramasubramanian, AK; Srinivasan, A; Torres, NS | 1 |
| Amaral, AJR; Pasparakis, G; Sanchez-Vazquez, B; Williams, GR; Yu, DG | 1 |
| Baldwin, WS; Gerard, PD; Reardon, DC; Sengupta, N | 1 |
| Chechetka, SA; Miyako, E; Pramanik, M; Pu, K; Yu, Y; Zhen, X | 1 |
| Haglund, C; Hermunen, K; Lantto, E; Österlund, P; Poussa, T | 1 |
| Barcellos, VA; Fonseca, FL; Joffe, LS; Kmetzsch, L; Reuwsaat, JCV; Rodrigues, ML; Schrank, A; Staats, CC; Vainstein, MH; Zimbres, ACG | 1 |
| Çömlekçi, E; Kutlu, HM; Vejselova Sezer, C | 1 |
| Ahn, EE; Dementiev, A; Doan, N; Gelsomino, M; Gorelik, A; Illes, K; Joachimiak, A; Nagar, B; Nguyen, H; Shabani, S | 1 |
| Chen, Y; Liu, Y; Yao, Y; Zhang, S; Zhu, Y | 1 |
| Bhat, OM; Hong, J; Huang, D; Li, G; Li, PL; Yuan, X | 1 |
| Dou, L; Li, H; Mai, Y; Sanchez-Vazquez, B; Trindade, RP; Williams, GR; Zhu, LM; Zou, Q | 1 |
| Du, X; Duan, Y; Guddat, LW; Hu, T; Jin, Z; Liu, X; Rao, Z; Sun, Y; Wang, H; Wu, Y; Xiao, G; Yang, H; Yang, K; Yang, X; Yu, J; Zhang, B; Zhang, L; Zhao, Y; Zhu, C; Zhu, Y | 1 |
| Bear, JC; Davies, GL; King, AM; Wells, CJR; Williams, GR; Zhang, Z | 1 |
| Janostiak, R; Malvi, P; Nagarajan, A; Wajapeyee, N; Zhang, X | 1 |
| Baldwin, WS; Gessner, EE; Ghent, BN; Shah, MH; van den Hurk, P; Westbrook, NE | 1 |
| Du, X; Peng, Y; Xing, J; Zhao, C | 1 |
| Faraji, S; Giudetti, G; Grigorenko, BL; Krylov, AI; Nemukhin, AV; Polyakov, I | 1 |
14 review(s) available for fluorouracil and carmofur
| Article | Year |
|---|---|
[Neurological disorders induced by antineoplastic drugs].
Topics: Animals; Antineoplastic Agents; Cell Division; Cisplatin; Fluorouracil; Humans; Methotrexate; Nervous System; Nervous System Diseases; Vincristine | 1992 |
Leukoencephalopathy following treatment with carmofur: a case report and review of the Japanese literature.
Topics: Antineoplastic Agents; Brain Diseases; Female; Fluorouracil; Humans; Japan; Middle Aged | 1989 |
Subacute leucoencephalopathy induced by carmofur, a 5-fluorouracil derivative.
Topics: Aged; Antineoplastic Agents; Electroencephalography; Female; Fluorouracil; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Tomography, X-Ray Computed | 1987 |
[Report on an autopsy of a cancer patient with Carmofur (HCFU) leukoencephalopathy].
Topics: Antineoplastic Agents; Brain; Female; Fluorouracil; Humans; Leukoencephalopathy, Progressive Multifocal; Middle Aged; Tomography, X-Ray Computed | 1987 |
Studies of analogs of fluorinated pyrimidine in Japan.
Topics: Animals; Antineoplastic Agents; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fluorouracil; Humans; Japan; Neoplasms; Neoplasms, Experimental; Tegafur; Uracil | 1981 |
[Gastrointestinal cancer and oral anticancer agents].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents; Camptothecin; Drug Combinations; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Organoplatinum Compounds; Oxonic Acid; Prodrugs; Pyridines; Tegafur; Uracil | 1999 |
[Recent development of oral anti-cancer drugs for breast cancer].
Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials, Phase II as Topic; Cyclophosphamide; Drug Administration Schedule; Fadrozole; Female; Floxuridine; Fluorouracil; Gonadotropin-Releasing Hormone; Humans; Medroxyprogesterone Acetate; Survival Rate; Tamoxifen; Toremifene | 1999 |
Adjuvant chemotherapy after resection of hepatocellular carcinoma causes deterioration of long-term prognosis in cirrhotic patients: metaanalysis of three randomized controlled trials.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Administration Schedule; Drug Tolerance; Epirubicin; Female; Fluorouracil; Hepatectomy; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Multivariate Analysis; Neoplasm Recurrence, Local; Prognosis; Survival Rate; Tegafur; Treatment Outcome | 2001 |
Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Maximum Tolerated Dose; Mitomycin; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Randomized Controlled Trials as Topic; Rectal Neoplasms; Survival Rate; Tegafur | 2004 |
An individual patient data meta-analysis of adjuvant therapy with carmofur in patients with curatively resected colon cancer.
Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Colonic Neoplasms; Digestive System Surgical Procedures; Disease-Free Survival; Fluorouracil; Humans; Neoplasm Recurrence, Local; Prognosis; Randomized Controlled Trials as Topic; Survival Rate | 2005 |
[Adjuvant chemotherapy for colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Combinations; Evidence-Based Medicine; Fluorouracil; Guidelines as Topic; Humans; Leucovorin; Lymph Node Excision; Neoplasm Staging; Survival Rate; Tegafur; Uracil | 2006 |
[Drug-induced leukoencephalopathy].
Topics: Antineoplastic Agents; Brain Edema; Cisplatin; Cytarabine; Fluorouracil; Humans; Hypertensive Encephalopathy; Immunosuppressive Agents; Methotrexate; Nervous System Diseases; Syndrome | 2007 |
[Drug-induced leukoencephalopathy].
Topics: Antineoplastic Agents; Antiviral Agents; Fluorouracil; Humans; Immunosuppressive Agents; Interferon-alpha; Methotrexate; Posterior Leukoencephalopathy Syndrome; Time Factors | 2007 |
[Leukoencephalopathy caused by antineoplastic drugs].
Topics: Antineoplastic Agents; Brain Diseases; Fluorouracil | 2008 |
41 trial(s) available for fluorouracil and carmofur
| Article | Year |
|---|---|
[A comparative clinical study of adjuvant chemotherapy of tumors in the head and neck areas by means of HCFU].
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Prognosis; Survival Rate | 1991 |
[Oral administration of 1-hexylcarbamoyl-5-fluorouracil (HCFU) in repeated arterial bolus chemotherapy in metastatic liver cancer of humans--preliminary randomized trial].
Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Prospective Studies | 1991 |
[Mitomycin C plus HCFU adjuvant chemotherapy for noncuratively resected cases of colorectal carcinoma. (Second report): 5-year survival rate. Cooperative Study Group of Kyushu and Chugoku for HCFU Adjuvant Chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Japan; Mitomycin; Mitomycins; Multicenter Studies as Topic; Prognosis; Prospective Studies; Random Allocation | 1989 |
[Adjuvant chemotherapy for gastric cancer--the third study. First report: central randomization by telephone method and analysis of patients' background factors].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Drug Administration Schedule; Fluorouracil; Humans; Japan; Mitomycin; Mitomycins; Multicenter Studies as Topic; Picibanil; Random Allocation; Stomach Neoplasms; Tegafur; Telephone | 1989 |
[Outcome of adjuvant mifurol chemotherapy in patients with resected colonic carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Drug Evaluation; Female; Fluorouracil; Follow-Up Studies; Humans; Japan; Male; Middle Aged; Mitomycin; Mitomycins; Multicenter Studies as Topic; Tegafur | 1989 |
[A randomized controlled trial comparing short-term MF chemotherapy with MF and long-term carmofur chemotherapy as an adjuvant to curative resection of stomach cancer].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Administration Schedule; Fluorouracil; Humans; Mitomycin; Mitomycins; Postoperative Period; Prognosis; Random Allocation; Stomach Neoplasms | 1986 |
[Prospective adjuvant chemotherapy, with mitomycin C plus long-term carmofur in colorectal cancer].
Topics: Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Drug Evaluation; Fluorouracil; Humans; Mitomycin; Mitomycins; Postoperative Care; Random Allocation; Rectal Neoplasms | 1986 |
[A randomized controlled trial of immunochemotherapy using carmofur (HCFU), mitomycin C and immunopotentiators in advanced gastric cancer following noncurative resection and nonresection].
Topics: Adjuvants, Immunologic; Adult; Aged; Clinical Trials as Topic; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Random Allocation; Stomach Neoplasms | 1986 |
Mitomycin C plus carmofur (HCFU) adjuvant chemotherapy for noncuratively resected cases of colorectal carcinoma (interim report).
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Mitomycin; Mitomycins; Prospective Studies; Random Allocation; Rectal Neoplasms | 1987 |
[Prospective adjuvant chemotherapy of mitomycin C plus HCFU for colorectal cancer (2d report)--6-year survival after surgery: Tokai Cooperative Study Group of Surgical Adjuvant Chemotherapy].
Topics: Adjuvants, Immunologic; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Mitomycin; Mitomycins; Postoperative Care; Rectal Neoplasms | 1988 |
[A randomized controlled trial comparing short-term MF chemotherapy with MF plus long-term HCFU chemotherapy as an adjuvant to a curative resection of stomach cancer: Mifurol Study Group for Stomach Cancer].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Clinical Trials as Topic; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Mitomycin; Mitomycins; Postoperative Care; Random Allocation; Stomach Neoplasms | 1988 |
[A randomized controlled study to compare 1-hexylcarbamoyl-5-fluorouracil (HCFU) and 1-(2-tetrahydrofuryl)-5-fluorouracil (Tegafur) for the prevention of post-operative recurrence of bladder cancer].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Postoperative Period; Random Allocation; Tegafur; Urinary Bladder; Urinary Bladder Neoplasms | 1985 |
[Clinical trial of carmofur (HCFU) in the treatment of malignant ovarian cancer--The first report: combination therapy with endoxan, mitomycin C, and toyomycin].
Topics: Adult; Aged; Antineoplastic Agents; Chromomycin A3; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hysterectomy; Mitomycin; Mitomycins; Ovarian Neoplasms | 1983 |
1-Hexylcarbamoyl-5-fluorouracil (HCFU)--a masked 5-fluorinated pyrimidine.
Topics: Adult; Aged; Animals; Antineoplastic Agents; Breast Neoplasms; Cats; Clinical Trials as Topic; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Rabbits; Rats | 1981 |
[Clinical effects of carmofur (Mifurol) on advanced and recurrent breast cancer in a cooperative study. Research association for re-evaluation of direct effects of Mifurol on breast cancer].
Topics: Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Agents; Breast Neoplasms; Dizziness; Drug Administration Schedule; Female; Fever; Fluorouracil; Humans; Middle Aged; Nausea; Neoplasm Recurrence, Local; Urination Disorders | 1995 |
Combination of carmofur and interferon-alpha-2B in advanced gastrointestinal cancer--a phase II pilot study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Synergism; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Pilot Projects; Recombinant Proteins; Treatment Outcome | 1994 |
[Long-term administration of carmofur as a post-operative adjuvant chemotherapy for cervical adenocarcinoma. Cervical Adenocarcinoma Cooperative Research Association].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Middle Aged; Neoplasm Recurrence, Local; Postoperative Period; Registries; Survival Rate; Uterine Cervical Neoplasms | 1994 |
[A comparative clinical study on the treatment of head and neck tumors by adjuvant chemotherapy with HCFU--Second Study by Kinki Head and Neck Tumor Study Group].
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Survival Rate | 1994 |
[Some problems of TS measurement after administration of fluoropyrimidines in colorectal cancer. Kinki Cooperative Study Group of Chemotherapy for Colorectal Carcinoma].
Topics: Adult; Aged; Antineoplastic Agents; Colorectal Neoplasms; Dipyridamole; Female; Fluorouracil; Humans; Male; Middle Aged; Thymidylate Synthase | 1993 |
Prospective adjuvant therapy with mitomycin C and carmofur (HCFU) for colorectal cancer, 10-year follow-up: Tokai HCFU Study Group, the first study for colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Japan; Male; Middle Aged; Mitomycin; Prospective Studies; Survival Rate | 1996 |
Postoperative chemotherapy for colorectal cancer by combining 5-fluorouracil infusion and 1-hexylcarbamoyl-5-fluorouracil administration after curative resection.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Postoperative Period; Prospective Studies; Survival Rate | 1996 |
[Comparative study of the combined effect of HCFU and dipyridamole (DP) in colorectal carcinoma--TS inhibition rate. Kinki Cooperative Study Group of Chemotherapy for Colorectal Carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dipyridamole; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunologic Factors; Japan; Male; Middle Aged; Thymidylate Synthase | 1996 |
Adjuvant oral chemotherapy to prevent recurrence after curative resection for hepatocellular carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Disease-Free Survival; Fluorouracil; Humans; Liver Neoplasms; Neoplasm Recurrence, Local; Survival Rate; Time Factors | 1996 |
[Randomized controlled study on adjuvant immunochemotherapy with carmofur (HCFU) for noncuratively resected and unresected gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Chi-Square Distribution; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Humans; Immunotherapy; Japan; Mitomycin; Picibanil; Stomach Neoplasms | 1996 |
Oral adjuvant chemotherapy with carmofur (HCFU) for colorectal cancer: five-year follow-up. Tokai HCFU Study Group--third study on colorectal cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Treatment Outcome | 1996 |
Improved surgical results after combining preoperative hyperthermia with chemotherapy and radiotherapy for patients with carcinoma of the rectum.
Topics: Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Hyperthermia, Induced; Male; Middle Aged; Preoperative Care; Prognosis; Radiotherapy, Adjuvant; Rectal Neoplasms; Survival Analysis | 1997 |
Adjuvant chemotherapy with epirubicin and carmofur after radical resection of hepatocellular carcinoma: a prospective randomized study.
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Epirubicin; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Neoplasm Recurrence, Local; Prospective Studies; Survival Rate | 1997 |
[Prospective controlled study on the usefulness of Carmofur as a postoperative adjuvant chemotherapy for colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Mitomycin; Neoplasm Invasiveness; Postoperative Care; Prospective Studies; Rectal Neoplasms; Survival Rate | 1997 |
[Comparative clinical study on 5-FU concentrations for oral HCFU and i.v. 5-FU].
Topics: Administration, Oral; Antineoplastic Agents; Breast Neoplasms; Cross-Over Studies; Drug Administration Schedule; Female; Fluorouracil; Humans; Injections, Intravenous; Survival Rate | 2000 |
Optimal duration of oral adjuvant chemotherapy with Carmofur in the colorectal cancer patients: the Kansai Carmofur Study Group trial III.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Survival Rate; Time Factors; Treatment Outcome | 2001 |
Randomized, controlled trial of lateral node dissection vs. nerve-preserving resection in patients with rectal cancer after preoperative radiotherapy.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Autonomic Nervous System; Disease-Free Survival; Female; Fluorouracil; Humans; Lymph Node Excision; Male; Middle Aged; Preoperative Care; Radiotherapy, Adjuvant; Rectal Neoplasms; Treatment Outcome | 2001 |
Postoperative chemoendocrine therapy for women with node-positive stage II breast cancer with combined cyclophosphamide, tamoxifen, and 1-hexylcarbamoyl-5-fluorouracil.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Middle Aged; Neoplasm Metastasis; Prospective Studies; Survival Rate; Tamoxifen | 2001 |
[Neo-adjuvant chemotherapy with carmofur for colorectal cancer--a multi-institutional randomized controlled study].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Neoadjuvant Therapy; Neoplasm Staging; Preoperative Care; Prospective Studies; Survival Rate | 2002 |
[Appropriate duration of postoperative oral adjuvant chemotherapy with HCFU for colorectal cancer].
Topics: Administration, Oral; Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Colonic Neoplasms; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Middle Aged; Postoperative Period; Rectal Neoplasms; Survival Rate | 2004 |
Randomized controlled trial of the efficacy of adjuvant immunochemotherapy and adjuvant chemotherapy for colorectal cancer, using different combinations of the intracutaneous streptococcal preparation OK-432 and the oral pyrimidines 1-hexylcarbamoyl-5-flu
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colectomy; Colonic Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Injections, Subcutaneous; Male; Middle Aged; Mitomycin; Neoplasm Staging; Picibanil; Pyrimidines; Radiotherapy, Adjuvant; Rectal Neoplasms; Survival Analysis; Tegafur; Treatment Outcome; Uracil | 2004 |
Postoperative adjuvant use of carmofur for early breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Carbazilquinone; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Mastectomy; Middle Aged; Neoplasm Staging; Treatment Outcome | 2003 |
1-hexylcarbamoyl-5-fluorouracil + cyclophosphamide + tamoxifen versus CMF + tamoxifen in women with lymph node-positive breast cancer after primary surgery: a randomized controlled trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Survival Rate; Tamoxifen | 2004 |
A multicenter randomized study comparing 5-fluorouracil continuous infusion (ci) plus 1-hexylcarbamoyl-5-fluorouracil and 5-FU ci alone in colorectal cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Nausea; Neoplasm Staging; Survival Analysis; Survival Rate; Time Factors; Treatment Outcome; Vomiting | 2005 |
[Multicenter comparative study of the recurrence-inhibitory effect of oral fluoropyrimidine drugs in patients with colorectal cancer following curative resection].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Leukopenia; Lymphatic Metastasis; Male; Middle Aged; Mitomycin; Rectal Neoplasms; Survival Rate; Tegafur; Uracil | 2005 |
Randomized trial of the efficacy of adjuvant chemotherapy for colon cancer with combination therapy incorporating the oral pyrimidine 1-hexylcarbamoyl-5-fluorouracil.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Combined Modality Therapy; Disease-Free Survival; Fluorouracil; Humans; Liver Neoplasms; Middle Aged; Mitomycin; Neoplasm Staging; Survival Rate; Treatment Outcome | 2006 |
Can carcinoembryonic antigen replace computed tomography in response evaluation of metastatic colorectal cancer?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Biomarkers, Tumor; Carcinoembryonic Antigen; Colorectal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Quinazolines; ROC Curve; Sensitivity and Specificity; Thiophenes; Tomography, X-Ray Computed | 2018 |
159 other study(ies) available for fluorouracil and carmofur
| Article | Year |
|---|---|
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Determination of 1-hexylcarbamoyl-5-fluorouracil and its metabolites in biomedical specimens by high-performance liquid chromatography.
Topics: Adult; Antineoplastic Agents; Chromatography, High Pressure Liquid; Female; Fluorouracil; Humans; Male; Neoplasms | 1979 |
Metabolic fate of 1-hexylcarbamoyl-5-fluorouracil in rats.
Topics: Animals; Biotransformation; Breath Tests; Feces; Fluorouracil; Kidney; Liver; Male; Rats; Tissue Distribution | 1978 |
[A case report of postoperative recurrent hepatocellular carcinoma effectively treated with HCFU administration combined with TAE].
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Combined Modality Therapy; Embolization, Therapeutic; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Postoperative Period | 1992 |
Studies on antitumor effects and mechanism of action of l-hexylcarbamoyl-5-fluorouracil by DNA/BrdU double staining using flow cytometry.
Topics: Antineoplastic Agents; Bromodeoxyuridine; Cell Cycle; DNA; Flow Cytometry; Fluorouracil; Humans; KB Cells; Pharyngeal Neoplasms; Staining and Labeling; Tumor Cells, Cultured | 1992 |
[Serum concentration of HCFU and 5-FU after oral administration of HCFU in postoperative digestive cancer patients].
Topics: Administration, Oral; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; Gastrectomy; Humans; Stomach Neoplasms | 1992 |
[Signification of liver metastases of colorectal cancer with special reference to recurrence in the residual liver after hepatic resection].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Doxorubicin; Drug Administration Schedule; Fluorouracil; Hepatectomy; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Mitomycin; Neoplasm Recurrence, Local | 1992 |
[Chemosensitivity of head and neck squamous cell carcinomas using subrenal capsule assay--comparative assay of 5-FU, FT, UFT, and HCFU and immunohistochemical study].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Fluorouracil; Head and Neck Neoplasms; Immunohistochemistry; Male; Mice; Mice, Inbred C3H; Subrenal Capsule Assay; Tegafur; Uracil | 1992 |
[Study of preventive effect of 1-hexylcarbamoyl-5-fluorouracil (HCFU) or combination of HCFU and 2.5-di-O-acetyl-D-glucaro (1-4) (6-3) dilactone (SLA) after preservative operation against bladder cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Combined Modality Therapy; Female; Fluorouracil; Glucaric Acid; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Postoperative Period; Urinary Bladder Neoplasms | 1992 |
[Potentiation of thymidylate synthetase (TS) inhibition by combined administration of HCFU and dipyridamole: preliminary report. Kinki Cooperative Study Group of Chemotherapy for Colorectal Carcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dipyridamole; Female; Fluorouracil; Humans; Male; Middle Aged; Pilot Projects; Thymidylate Synthase | 1992 |
[Improvement of stability and bioavailability of 1-hexylcarbamoyl-5-fluorouracil (HCFU) by O-carboxymethyl-O-ethyl-beta- cyclodextrin].
Topics: Administration, Oral; Animals; Antineoplastic Agents; beta-Cyclodextrins; Cyclodextrins; Delayed-Action Preparations; Dogs; Drug Carriers; Drug Stability; Fluorouracil; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Absorption; Male; Solubility | 1991 |
Comparative antitumor activity of 5-fluorouracil and its prodrugs in combination with hyperthermia in vitro.
Topics: Antineoplastic Agents; Cell Survival; Floxuridine; Fluorouracil; Hot Temperature; Humans; Infant, Newborn; Prodrugs; Tegafur; Tumor Cells, Cultured | 1991 |
Antitumor activity of fluoropyrimidines and thymidylate synthetase inhibition.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma; Colonic Neoplasms; Enzyme Activation; Fluorouracil; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Stomach Neoplasms; Thymidylate Synthase | 1991 |
Subrenal capsule assay using nude mice as a predictor of the response of the gastric cancer to chemotherapy.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Mitomycins; Neoplasm Transplantation; Stomach Neoplasms; Subrenal Capsule Assay | 1991 |
Adjuvant hepatic intra-arterial chemotherapy after potentially curative hepatectomy for liver metastases from colorectal cancer: a pilot study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitomycin; Neoplasm Recurrence, Local; Pilot Projects; Survival Rate | 1991 |
1-Hexylcarbamoyl-5-fluorouracil alters the expression of heat shock protein in HeLa cells.
Topics: Cells, Cultured; Clone Cells; Fluorouracil; Heat-Shock Proteins; HeLa Cells; Humans; Immunohistochemistry; Stem Cells | 1991 |
Carmofur-induced organic mental disorders.
Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Electroencephalography; Female; Fluorouracil; Follow-Up Studies; Humans; Leukoencephalopathy, Progressive Multifocal; Lung Neoplasms; Neuropsychological Tests; Substance-Related Disorders; Tomography, X-Ray Computed | 1990 |
[Evaluation of intraperitoneal cancer chemotherapy using an implantable reservoir in patients with peritonitis carcinomatosa].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Cisplatin; Colorectal Neoplasms; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Male; Middle Aged; Mitomycin; Mitomycins; Peritonitis; Prognosis; Stomach Neoplasms; Tegafur | 1990 |
[Chemotherapy with fluoropyrimidines for MOPC-104E plasmacytoma transplanted in mice with CCl4 induced chronic liver dysfunction].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Floxuridine; Fluorouracil; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Plasmacytoma; Tegafur; Uracil | 1990 |
Oral carmofur in advanced gastrointestinal cancer.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms | 1990 |
[Effect of concomitant use of anticancer drugs and a Ca2+ antagonist, on human gastric cancer transplanted into nude mice].
Topics: Animals; Antineoplastic Agents; Drug Combinations; Fluorouracil; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Nicardipine; Stomach Neoplasms; Transplantation, Heterologous | 1990 |
[5-FU concentration in portal blood after oral administration of 1-hexylcarbamoyl-5-fluorouracil (HCFU)].
Topics: Administration, Oral; Antineoplastic Agents; Digestive System Neoplasms; Drug Combinations; Fluorouracil; gamma-Globulins; Humans; Immunotoxins; Melphalan; Portal System | 1988 |
A case of carmofur-induced leukoencephalopathy--MR images and CT findings.
Topics: Aged; Antineoplastic Agents; Colonic Neoplasms; Female; Fluorouracil; Humans; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Tomography, X-Ray Computed | 1989 |
Phase II evaluation of peroral carmofur, cyclophosphamide, and hexamethylmelamine as a second-line therapy in advanced epithelial ovarian carcinoma.
Topics: Administration, Oral; Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Middle Aged; Ovarian Neoplasms; Prospective Studies | 1989 |
[A case of hepatocellular carcinoma (HCC) with lung metastasis which responded to chemotherapy with a single use of 1-hexylcarbamoyl-5-fluorouracil (HCFU)].
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Remission Induction | 1989 |
Low dose 1-hexylcarbamoyl-5-fluorouracil (HCFU) recommended for cirrhotic patients with hepatocellular carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Female; Fluorouracil; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged | 1989 |
[HCFU and 5-fluorouracil levels in the blood and tissue of hepatocellular carcinoma after oral administration of HCFU].
Topics: Administration, Oral; Antineoplastic Agents; Carcinoma, Hepatocellular; Female; Fluorouracil; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Liver Neoplasms; Male; Middle Aged; Tissue Distribution | 1989 |
Application of PHYCON 6600 to achieve sustained release of an antitumor drug (carmofur).
Topics: Animals; Antineoplastic Agents; Delayed-Action Preparations; Drug Implants; Excipients; Fluorouracil; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Silicone Gels; Silicones | 1989 |
[A case of non-functioning adrenal cortical carcinoma with pulmonary and bony metastases].
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Antineoplastic Agents; Bone Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Lung Neoplasms; Middle Aged; Mitotane | 1989 |
Hyperthermia enhances the in vitro activity of 1-hexylcarbamoyl-5-fluorouracil compared to that of 5-fluorouracil.
Topics: Antineoplastic Agents; Combined Modality Therapy; Fluorouracil; HeLa Cells; Humans; Hyperthermia, Induced | 1989 |
[A case of renal cell carcinoma with lung metastases successfully treated by interferon-beta].
Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Fluorouracil; Humans; Interferon Type I; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Remission Induction | 1989 |
[Antitumor effects of 5-fluorouracil-bound organic silicon compound].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Ethylamines; Female; Fluorouracil; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Organosilicon Compounds; Pyrimidinones; Sarcoma, Experimental; Transplantation, Heterologous | 1989 |
[1-Hexylcarbamoyl-5-fluorouracil (HCFU) effective in hepatocellular carcinoma metastatic to the lungs--a case report].
Topics: Administration, Oral; Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms | 1987 |
[5-FU and HCFU concentrations in serum and tissues in hepatocellular carcinoma after HCFU oral administration].
Topics: Administration, Oral; Carcinoma, Hepatocellular; Fluorouracil; Humans; Liver; Liver Neoplasms | 1988 |
[Release profiles of 5-fluorouracil and its lipophilic derivatives from lipiodol solutions].
Topics: Fluorouracil; Humans; Hydrogen-Ion Concentration; Infusions, Intra-Arterial; Iodized Oil; Solutions | 1988 |
[Experimental study of anti-tumor agent microcapsules--the effects of embolization and drug releasing].
Topics: Animals; Capsules; Dogs; Embolization, Therapeutic; Fluorouracil; Humans; Iodized Oil; Mice; Peritoneal Neoplasms; Rabbits | 1988 |
[Trans-arterial embolization or transarterial infusion of anti-cancer drugs suspended in a lipid contrast medium against unresectable metastatic liver cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Embolization, Therapeutic; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Iodized Oil; Liver Neoplasms; Maleic Anhydrides; Mitomycin; Mitomycins; Polystyrenes; Prognosis; Suspensions; Zinostatin | 1988 |
[The determination of thymidylate synthetase inhibition for testing fluoropyrimidines--pharmacokinetics and metabolism of carmofur (HCFU) in patients with gynecologic malignancies--Tokai HCFU Study Group for Gynecologic Malignancies].
Topics: Antineoplastic Agents; Female; Floxuridine; Fluorouracil; Genital Neoplasms, Female; Half-Life; Humans; Kinetics; Thymidylate Synthase | 1986 |
[Effects of derivatives of Ara-C, 5-fluorouracil and nitrosourea against intracerebral implanted L1210 leukemia].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Cytarabine; Fluorouracil; Leukemia L1210; Mice; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Streptozocin; Tegafur; Uracil | 1987 |
The antiproliferative effects of fluoropyrimidine derivatives against human tumor xenografts in a subrenal capsule assay.
Topics: Animals; Antineoplastic Agents; Body Weight; Cell Division; Colorectal Neoplasms; Floxuridine; Fluorouracil; Humans; Male; Mice; Mice, Nude; Stomach Neoplasms; Subrenal Capsule Assay; Tegafur; Transplantation, Heterologous | 1988 |
[A clinical study of radiotherapy with HCFU for advanced and recurrent breast cancers. Radiation and HCFU Study Group for breast cancer].
Topics: Adenocarcinoma, Scirrhous; Adult; Aged; Breast Neoplasms; Carcinoma; Combined Modality Therapy; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Middle Aged; Radiotherapy Dosage | 1985 |
[Experimental chemotherapy of ovarian cancers heterotransplanted in nude mice].
Topics: Adenocarcinoma, Mucinous; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Recurrence, Local; Ovarian Neoplasms; Teratoma | 1985 |
[One-shot therapy and transcatheter arterial embolization (TAE) therapy of unresectable hepatocellular carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Doxorubicin; Embolization, Therapeutic; Female; Fluorouracil; Hepatic Artery; Humans; Injections, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins | 1985 |
[Blood level of 5-fluorouracil (5-FU) by oral administration of 1-hexylcarbamoyl-5-fluorouracil (HCFU) and tegafur in patients with hepatocellular carcinoma].
Topics: Administration, Oral; Adult; Antineoplastic Agents; Carcinoma, Hepatocellular; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Tegafur | 1985 |
Reversible leukoencephalopathy caused by 5-fluorouracil derivatives, presenting as akinetic mutism.
Topics: Anal Gland Neoplasms; Animals; Breast Neoplasms; Carcinoma; Female; Fluorouracil; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Movement Disorders; Mutism; Tegafur; Tomography, X-Ray Computed | 1986 |
[Combined effects of radiation and 5-FU derivatives].
Topics: Adenocarcinoma; Animals; Cell Division; Fluorouracil; Male; Mice; Radiotherapy Dosage; Tegafur | 1986 |
[Chemosensitivity testing for 5-FU and 5-FU derivatives using subrenal capsule assay].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colony-Forming Units Assay; Fluorouracil; Humans; Lung Neoplasms; Stomach Neoplasms; Tegafur; Tumor Stem Cell Assay; Uracil | 1987 |
[Human colorectal carcinoma is more sensitive to HCFU than 5-FU and tegafur in in vitro and in vivo drug sensitivity tests].
Topics: Animals; Colonic Neoplasms; Fluorouracil; Humans; Mice; Rectal Neoplasms; Subrenal Capsule Assay; Tegafur; Tumor Cells, Cultured | 1988 |
Colorectal carcinoma in vitro is more sensitive to 1-hexylcarbamoyl-5-fluorouracil compared with six other antitumor drugs: carboquone, Adriamycin, mitomycin C, aclacinomycin A, cisplatin, 5-fluorouracil.
Topics: Aclarubicin; Antineoplastic Agents; Carbazilquinone; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Humans; In Vitro Techniques; Mitomycin; Mitomycins; Naphthacenes; Rectal Neoplasms; Succinate Dehydrogenase | 1988 |
Sensitivity test for 5-fluorouracil and its analogues, 1-(2-tetrahydrofuryl)-5-fluorouracil, uracil/1-(2-tetrahydrofuryl)-5-fluorouracil (4:1) and 1-hexylcarbamoyl-5-fluorouracil, using the subrenal capsule assay.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Resistance; Fluorouracil; Gastrointestinal Neoplasms; Humans; Kidney; Male; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Subrenal Capsule Assay; Tegafur; Uracil | 1988 |
UFT is more antineoplastic against gastric carcinoma than 5-fluorouracil, 1-(2-tetrahydrofuryl)-5-fluorouracil and 1-hexylcarbamoyl-5-fluorouracil.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Male; Mice; Stomach Neoplasms; Subrenal Capsule Assay; Tegafur; Uracil | 1988 |
Effect of 1-hexylcarbamoyl-5-fluorouracil on development of rat urinary bladder tumor induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Antineoplastic Agents; Body Weight; Butylhydroxybutylnitrosamine; Fluorouracil; Male; Nitrosamines; Organ Size; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1988 |
[Inhibition of thymidylate synthetase and antiproliferative effect by 1-hexylcarbamoyl-5-fluorouracil].
Topics: Animals; Antineoplastic Agents; Cell Division; Esophageal Neoplasms; Fluorouracil; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Stomach Neoplasms; Thymidylate Synthase | 1988 |
Subacute neurotoxicity of 5-fluorouracil and its derivative, carmofur, in cats.
Topics: Animals; Behavior, Animal; Cats; Cerebellum; Female; Fluorouracil; Male; Microscopy, Electron; Neurons; Neurotoxins | 1988 |
[Estimation of 1-hexylcarbamoyl-5-fluorouracil (HCFU) and 5-FU concentrations in sera and resected specimens from patients with ovarian tumors].
Topics: Administration, Oral; Female; Fluorouracil; Humans; Ovarian Neoplasms; Ovariectomy; Ovary; Uterus | 1988 |
[A case of leukoencephalopathy caused by HCFU].
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Diseases; Cisplatin; Combined Modality Therapy; Electroencephalography; Female; Fluorouracil; Granulosa Cell Tumor; Humans; Hysterectomy; Neoplasms, Multiple Primary; Ovarian Neoplasms; Ovariectomy; Teratoma | 1988 |
Enhancement of antitumor effects of 1-hexylcarbamoyl-5-fluorouracil combined with hyperthermia on Ehrlich ascites tumor in vivo and Nakahara-Fukuoka sarcoma cell in vitro.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cell Survival; Combined Modality Therapy; Fluorouracil; Hyperthermia, Induced; Mice; Neoplasm Transplantation; Sarcoma, Experimental; Tumor Cells, Cultured | 1988 |
[Effect of dimethyl beta-cyclodextrin on oral or rectal absorption of 1-hexylcarbamoyl-5-fluorouracil (HCFU)].
Topics: Administration, Oral; Administration, Rectal; Animals; Antineoplastic Agents; beta-Cyclodextrins; Cyclodextrins; Dextrins; Fluorouracil; Male; Rabbits; Starch | 1988 |
Principia of cancer therapy. XIX. Effects of per rectum carmofur on radiotherapeutic efficacy of rectal carcinomas.
Topics: Carcinoembryonic Antigen; Carcinoma; Fluorouracil; Humans; Metabolic Clearance Rate; Rectal Neoplasms; Suppositories | 1987 |
[Studies on the pleural permeability of carmofur].
Topics: Administration, Oral; Fluorouracil; Humans; Neoplasms; Permeability; Pleural Effusion | 1987 |
[Study on effectiveness of carmofur (Mifurol) in urogenital carcinoma, especially bladder cancer, as a post-operative adjuvant chemotherapeutic agent].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Postoperative Period; Prognosis; Urinary Bladder Neoplasms | 1987 |
Improvement of chemical instability of carmoful in beta-cyclodextrin solid complex by utilizing some organic acids.
Topics: beta-Cyclodextrins; Chemical Phenomena; Chemistry; Cyclodextrins; Drug Stability; Fluorouracil | 1987 |
[Effect of post operative maintenance chemotherapy against ovarian cancer].
Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Humans; Mice; Mice, Nude; Neoplasm Recurrence, Local; Neoplasm Transplantation; Ovarian Neoplasms; Teratoma | 1987 |
[A case of esophageal cancer of superficial depressive type in an advanced age successfully treated with HCFU].
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Esophageal Neoplasms; Fluorouracil; Humans; Male | 1987 |
Disulfiram-like reaction associated with carmofur after celiac plexus alcohol block.
Topics: Aged; Alcohol Deterrents; Antineoplastic Agents; Autonomic Nerve Block; Celiac Plexus; Ethanol; Fluorouracil; Humans; Male | 1987 |
[A case of recurrent gastric cancer successfully treated with a combination of cisplatin and carmofur].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Stomach Neoplasms | 1987 |
1-Hexylcarbamoyl-5-fluorouracil is more cytostatic than 5-fluorouracil against human tumors in vitro.
Topics: Antineoplastic Agents; Cell Survival; Fluorouracil; HeLa Cells; Humans; Neoplasms; Succinate Dehydrogenase; Tumor Cells, Cultured | 1987 |
[Clinical effect of HCFU therapy of head and neck cancer].
Topics: Administration, Oral; Antineoplastic Agents; Drug Administration Schedule; Drug Evaluation; Fluorouracil; Head and Neck Neoplasms; Humans | 1986 |
[Clinical study of HCFU and radiation therapy in head and neck cancer].
Topics: Antineoplastic Agents; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Radiotherapy Dosage | 1986 |
[The dose finding of adjuvant carmofur chemotherapy in patients with stomach cancer].
Topics: Drug Administration Schedule; Fluorouracil; Humans; Stomach Neoplasms | 1986 |
[Clinical study of HCFU in combination with irradiation therapy in squamous cell carcinoma of the head and neck].
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Radiotherapy Dosage | 1986 |
[Central nervous system toxicity of carmofur, an antineoplastic drug].
Topics: Aged; Central Nervous System Diseases; Electroencephalography; Female; Fluorouracil; Humans; Male; Tomography, X-Ray Computed | 1986 |
[Combination effects of CDDP, ACR and HCFU on progressive urothelial tumors].
Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Humans; Kidney Neoplasms; Kidney Pelvis; Male; Middle Aged; Naphthacenes; Ureteral Neoplasms; Urinary Bladder Neoplasms; Urologic Neoplasms | 1985 |
[Influence of immunopotentiators on the activation of 5-FU derivatives].
Topics: Adjuvants, Immunologic; Animals; Biological Products; Cytochrome P-450 Enzyme System; Fluorouracil; In Vitro Techniques; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Picibanil; Proteoglycans; Rats; Rats, Inbred Strains; Tegafur | 1985 |
[Evaluation of combined radiotherapy of gastric carcinoma].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Middle Aged; Prognosis; Radiotherapy, High-Energy; Stomach Neoplasms; Tegafur | 1985 |
[Comparison of the concentration of HCFU, tegafur and 5-FU in the thoracic duct lymph after oral administration of HCFU and tegafur].
Topics: Administration, Oral; Female; Fluorouracil; Humans; Lymph; Middle Aged; Tegafur; Thoracic Duct | 1985 |
[A case of toxic leucoencephalopathy induced by 5FU derivatives].
Topics: Antineoplastic Agents; Brain; Brain Diseases; Breast Neoplasms; Female; Fluorouracil; Humans; Middle Aged; Tegafur | 1985 |
[Distribution of 1-hexycarbamoyl-5-fluorouracil in rats and human patients, and clinical results in patients with colorectal cancer].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Rats; Rats, Inbred Strains; Rectal Neoplasms | 1986 |
[Effects of combination therapy of carmofur and nicardipine of human gastric cancer in nude mice].
Topics: Animals; Cell Line; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nicardipine; Nifedipine; Stomach Neoplasms | 1985 |
[Effects of urokinase on the transfer of 1-hexylcarbamoyl-5-fluorouracil (HCFU) into the blood, bile and pancreatic juice].
Topics: Administration, Oral; Antineoplastic Agents; Bile; Fluorouracil; Humans; Pancreatic Juice; Pancreatic Neoplasms; Urokinase-Type Plasminogen Activator | 1985 |
[Clinical evaluation of 1-hexylcarbamoyl-5-fluorouracil (HCFU) in hepatocellular carcinoma].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Speech Disorders; Unconsciousness | 1984 |
[Role of oral administration of 1-hexyl-carbamoyl-5-fluorouracil (HCFU) for multimodal treatment of inoperable cirrhotics with hepatocellular carcinoma].
Topics: Administration, Oral; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Embolization, Therapeutic; Female; Fluorouracil; Hepatic Artery; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Picibanil; Prognosis | 1984 |
[Intraarterial Adriamycin for patients with hepatocellular carcinoma and metastatic liver carcinoma].
Topics: Adult; Aged; Alkaline Phosphatase; Carcinoma, Hepatocellular; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Injections, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Stomach Neoplasms | 1984 |
[Combination chemotherapy with neocarzinostatin(NCS), HCFU and picibanil(NHO therapy) for advanced carcinoma of the digestive system--a comparative study with NF, and NFO therapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Digestive System Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Picibanil; Zinostatin | 1984 |
[Cerebrospinal fluid distributions of systemically administered fluorinated pyrimidines].
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Ependymoma; Female; Fluorouracil; Glioblastoma; Humans; Male; Middle Aged; Tegafur | 1983 |
[Combination chemotherapy of CIS-diamminedichloroplatinum (II) and fluoropyrimidine derivatives for advanced gastric cancer: a preliminary report].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms; Tegafur | 1984 |
Neuropathologic study on chronic neurotoxicity of 5-fluorouracil and its masked compounds in dogs.
Topics: Animals; Axons; Brain; Dogs; Female; Fluorouracil; Male; Microscopy, Electron; Myelin Sheath; Neuroglia; Neurons; Tegafur; Vacuoles | 1984 |
[Blood concentration of HCFU in gastrectomized patients].
Topics: Fluorouracil; Gastrectomy; Humans; Postoperative Period; Stomach Neoplasms | 1984 |
Concentrations of a new antitumor agent, 1-hexylcarbamoyl-5-fluorouracil in serum and gynecologic tumor tissue.
Topics: Antineoplastic Agents; Female; Fluorouracil; Humans; Ovarian Neoplasms; Uterine Cervical Neoplasms | 1983 |
Excretion of 1-hexylcarbamoyl-5-fluorouracil in urine of mice.
Topics: Animals; beta-Alanine; Female; Fluorouracil; Mice; Mice, Inbred Strains | 1981 |
[Clinical study of HCFU and radiation therapy for head and neck cancer].
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Maxillary Sinus; Middle Aged; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms | 1983 |
Metabolic fate on 1-hexylcarbamoyl-5-fluorouracil and 5-fluorouracil in mice bearing ascites sarcoma 180.
Topics: Administration, Oral; Animals; Ascitic Fluid; Female; Fluorouracil; Kinetics; Mice; Sarcoma 180 | 1981 |
[Evaluation of the therapeutic effect of HCFU (1-hexylcarbamoyl-5-fluorouracil) on non-resectable stomach cancer].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms | 1982 |
[Evaluation of the optimum method of administration of a new antineoplastic agent, HCFU, based on the serum 5-FU concentration following oral administration].
Topics: Administration, Oral; Antineoplastic Agents; Fluorouracil; Humans | 1982 |
[Phase II study of carmofur (HCFU) fine granules].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Child; Child, Preschool; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Stomach Neoplasms | 1982 |
Metabolism of 1-hexylcarbamoyl-5-fluorouracil (HCFU), a new antitumour agent, in rats, rabbits and dogs.
Topics: Absorption; Animals; Antineoplastic Agents; Dogs; Fluorouracil; Kinetics; Male; Oxidation-Reduction; Rabbits; Rats; Species Specificity | 1981 |
Effect of 1-hexylcarbamoyl-5-fluorouracil on spontaneous mammary adenocarcinoma of mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Drug Administration Schedule; Female; Fluorouracil; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice | 1980 |
Quantitative determination of 1-hexylcarbamoyl-5-fluorouracil and its metabolites in man.
Topics: Chromatography, High Pressure Liquid; Fluorouracil; Humans; Time Factors | 1981 |
Review of a new antimetabolic agent 1-hexylcarbamoyl-5-fluorouracil (HCFU).
Topics: Aged; Animals; Drug Evaluation; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Male; Mice; Middle Aged; Neoplasms; Neoplasms, Experimental; Rats | 1980 |
Determination of two new metabolites of 1-hexylcarbamoyl-5-fluorouracil in biomedical specimens by high-performance liquid chromatography.
Topics: Adult; Antineoplastic Agents; Body Fluids; Chromatography, High Pressure Liquid; Fluorouracil; Humans; Kinetics; Male | 1980 |
Inhibition of murine colon adenocarcinomas and Lewis lung carcinoma by 1-hexylcarbamoyl-5-fluorouracil.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; In Vitro Techniques; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental | 1980 |
Chemotherapeutic study on canine gastric cancer induced by N-ethyl-N'-nitro-N-nitrosoguanidine.
Topics: Adenocarcinoma; Animals; Dogs; Fluorouracil; Humans; Male; Methylnitronitrosoguanidine; Stomach Neoplasms | 1980 |
Antitumor activity of metabolites of 1-hexylcarbamoyl-5-fluorouracil and related compounds against L1210 leukemia in vivo and L5178Y lymphoma cells in vitro.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Fluorouracil; Leukemia L1210; Leukemia L5178; Male; Mice | 1980 |
Metabolic fate of 1-hexylcarbamoyl-5-fluorouracil after oral administration in mice.
Topics: Administration, Oral; Animals; Female; Fluorouracil; Intestine, Small; Kidney; Liver; Lung; Mice | 1980 |
Fetal liver micronucleus assay in mice of 5-fluorouracil and related compounds.
Topics: Animals; Bone Marrow; Dose-Response Relationship, Drug; Female; Fetus; Fluorouracil; Liver; Male; Mice; Mice, Inbred C3H; Micronucleus Tests; Tegafur | 1993 |
[Transfer of carmofur (HCFU) to the serum, bile, pancreatic juice and pancreatic tumor tissue in the cases of peri-pancreatic head cancer].
Topics: Administration, Oral; Antineoplastic Agents; Bile; Biliary Tract Neoplasms; Fluorouracil; Humans; Pancreatic Juice; Pancreatic Neoplasms | 1995 |
[TS inhibition rate and flow cytometric analysis of DNA content in preoperative chemotherapy with biochemical modulator].
Topics: Administration, Oral; Adult; Aged; Chemotherapy, Adjuvant; Colorectal Neoplasms; Dipyridamole; DNA, Neoplasm; Female; Flow Cytometry; Fluorouracil; Humans; Male; Middle Aged; Preoperative Care; Thymidylate Synthase | 1994 |
[In vitro effect of 1-hexylcarbamoyl-5-fluorouracil on human cancer cell lines of gastrointestinal tract].
Topics: Antineoplastic Agents; Fluorouracil; Gastrointestinal Neoplasms; Humans; Tumor Cells, Cultured | 1993 |
[Evaluation of neoadjuvant combination chemotherapy with pirarubicin, carmofur and tamoxifen citrate on outpatients with advanced and recurrence breast cancer].
Topics: Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Doxorubicin; Female; Fluorouracil; Humans; Middle Aged; Neoplasm Recurrence, Local; Outpatients; Tamoxifen; Treatment Outcome | 1994 |
[The present status of chemotherapy for hepatocellular carcinoma].
Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Doxorubicin; Drug Delivery Systems; Fluorouracil; Humans; Infusion Pumps; Infusions, Intra-Arterial; Liver Neoplasms; Mitomycin; Survival Rate; Tegafur; Uracil | 1993 |
[Study on the combined preoperative treatment with CDDP and HCFU for gastric cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; Male; Middle Aged; Preoperative Care; Stomach Neoplasms; Thymidylate Synthase | 1996 |
Carmofur-induced leukoencephalopathy: MRI.
Topics: Antineoplastic Agents; Brain; Brain Damage, Chronic; Breast Neoplasms; Chemotherapy, Adjuvant; Demyelinating Diseases; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Middle Aged; Neurologic Examination | 1995 |
Metabolites of 5-fluorouracil, alpha-fluoro-beta-alanine and fluoroacetic acid, directly injure myelinated fibers in tissue culture.
Topics: Animals; Animals, Newborn; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cerebellum; Culture Techniques; Fluorouracil; Immunohistochemistry; Mice; Mice, Inbred ICR; Microscopy, Phase-Contrast; Nerve Fibers, Myelinated; Tegafur | 1996 |
[Characterization of spontaneous liver metastatic model of BALB/c retroperitoneal sarcoma (LMFS) injected in footpad and antitumor effects of HCFU].
Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Fluorouracil; Liver; Liver Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Organ Size; Retroperitoneal Neoplasms; Sarcoma, Experimental; Tumor Cells, Cultured | 1997 |
[A case of recurrent gastric cancer with liver metastasis responding to combination chemotherapy with cisplatin and carmofur].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Fluorouracil; Humans; Liver Neoplasms; Lymphatic Metastasis; Male; Stomach Neoplasms | 1997 |
Alcohol consumption enhances liver metastasis in colorectal carcinoma patients.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Analysis of Variance; Antineoplastic Agents; Blood Vessels; Carcinoma; Chemotherapy, Adjuvant; Colonic Neoplasms; Ethanol; Female; Fluorouracil; Follow-Up Studies; gamma-Glutamyltransferase; Humans; Intestinal Mucosa; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Invasiveness; Neoplasm Staging; Rectal Neoplasms; Risk Factors | 1998 |
[A case of multiple liver metastases showing good response by administration of carmofur alone in an aged patient with colorectal cancer].
Topics: Adenocarcinoma; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Liver Neoplasms | 1999 |
[Anti-tumor effects of carmofur on human 5-FU resistant cells].
Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Mice; Mice, Nude; Tumor Cells, Cultured | 1999 |
[Successful endocrine chemotherapy in patients with multiple bone metastases of breast cancer--a case report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Humans; Medroxyprogesterone; Middle Aged; Tamoxifen | 1999 |
[Effects of HCFU and TNP 470 on liver metastasis of BALB/c retroperitoneal sarcoma (LMFS)].
Topics: Angiogenesis Inhibitors; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cyclohexanes; Female; Fluorouracil; Liver Neoplasms; Mice; Mice, Inbred BALB C; O-(Chloroacetylcarbamoyl)fumagillol; Retroperitoneal Neoplasms; Sarcoma, Experimental; Sesquiterpenes; Tumor Cells, Cultured | 1999 |
Induction of apoptosis in metastatic foci from human gastric cancer xenografts in nude mice and reduction of circulating tumor cells in blood by 5-FU and 1-hexylcarbamoyl-5-fluorouracil.
Topics: Animals; Antigens, Nuclear; Antineoplastic Agents; Apoptosis; Cell Division; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Ki-67 Antigen; Lung; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Metastasis; Nuclear Proteins; Stomach Neoplasms; Time Factors; Transplantation, Heterologous | 1999 |
[Weekly low-dose CPT-11 and HCFU for advanced colorectal cancer on an outpatient treatment basis].
Topics: Adenocarcinoma; Administration, Oral; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Lymph Node Excision; Lymphatic Metastasis | 2000 |
[Antitumor activity of 1-hexylcarbamoyluracil which is carmofur substituted fluorine for hydrogen].
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Female; Fluorouracil; Mice; Mice, Inbred BALB C; Stomach Neoplasms; Tumor Cells, Cultured; Uracil | 2000 |
Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 16). Effects of short-term administration of carmofur on spermatogenesis.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Epididymis; Fluorouracil; Longevity; Male; Organ Size; Rats; Rats, Sprague-Dawley; Seminiferous Epithelium; Spermatogenesis; Testis; Time Factors; Toxicity Tests | 2000 |
5-fluorouracil-induced leukoencephalopathy in patients with breast cancer.
Topics: Adenocarcinoma, Mucinous; Adult; Anti-Inflammatory Agents; Antineoplastic Agents; Brain; Breast Neoplasms; Carcinoma, Ductal, Breast; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Glucocorticoids; Humans; Magnetic Resonance Imaging; Methylprednisolone; Middle Aged; Nervous System Diseases; Prednisolone; Radiography | 2001 |
[Inhibition of HCFU absorption after resection for gastric cancer--application of hydroxyaluminium gel].
Topics: Adult; Aged; Aluminum Hydroxide; Antineoplastic Agents; Chemotherapy, Adjuvant; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Female; Fluorouracil; Gastrectomy; Humans; Magnesium Hydroxide; Male; Middle Aged; Patient Compliance; Stomach Neoplasms | 2001 |
A phase I study of raltitrexed (Tomudex) combined with carmofur in metastatic colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Gastrointestinal Diseases; Hematologic Diseases; Humans; Male; Maximum Tolerated Dose; Middle Aged; Nervous System Diseases; Quinazolines; Salvage Therapy; Thiophenes; Treatment Outcome | 2001 |
Docetaxel alone or orally combined with 5-fluorouracil and its derivatives: effects on mouse mammary tumor cell line MM2 in vitro and in vivo.
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Docetaxel; Drug Synergism; Female; Floxuridine; Fluorouracil; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Paclitaxel; Prodrugs; Taxoids; Thymidine Phosphorylase; Tumor Cells, Cultured; Up-Regulation | 2001 |
[A case of reversible carmofur-induced leukoencephalopathy].
Topics: Adult; Antineoplastic Agents; Brain; Brain Diseases; Breast Neoplasms; Female; Fluorouracil; Humans; Magnetic Resonance Imaging | 2001 |
Plasma, intestine and tumor levels of 5-fluorouracil in mice bearing L1210 ascites tumor following oral administration of 5-fluorouracil, UFT (mixed compound of tegafur and uracil), carmofur and 5'-deoxy-5-fluorouridine.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Drug Combinations; Floxuridine; Fluorouracil; Intestinal Mucosa; Leukemia L1210; Male; Mice; Tegafur; Uracil | 2001 |
Diffusion-weighted MR imaging of Carmofur-induced leukoencephalopathy.
Topics: Adult; Antineoplastic Agents; Brain; Brain Diseases; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Diffusion; Encephalomalacia; Female; Fluorouracil; Humans; Image Enhancement; Magnetic Resonance Imaging; Male; Middle Aged; Sigmoid Neoplasms | 2001 |
Raltitrexed treatment promotes systemic inflammatory reaction in patients with colorectal carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; C-Reactive Protein; Colorectal Neoplasms; Cross-Sectional Studies; Fatigue; Female; Fever; Fluorouracil; Humans; Inflammation; Interleukin-6; Liver Neoplasms; Longitudinal Studies; Lung Neoplasms; Male; Middle Aged; Quinazolines; Thiophenes; Thymidylate Synthase; Tumor Necrosis Factor-alpha | 2002 |
[Analysis of microsatellite instability and p53 LOH in advanced colorectal cancers--first report of the No. 3 protocol].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Genes, p53; Humans; Loss of Heterozygosity; Male; Microsatellite Repeats; Prognosis; Rectal Neoplasms | 2004 |
Delivery of hydrophobised 5-fluorouracil derivative to brain tissue through intravenous route using surface modified nanogels.
Topics: Animals; Autoradiography; Brain; Drug Compounding; Drug Delivery Systems; Excipients; Female; Fluorouracil; Gels; Injections, Intravenous; Light; Male; Nanostructures; Particle Size; Polysorbates; Prodrugs; Rabbits; Radiopharmaceuticals; Scattering, Radiation; Technetium; Tissue Distribution | 2006 |
S-1 (TS-1) maintained complete response for approximately 10 years in a case of metastatic breast cancer.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Immunohistochemistry; Lung Neoplasms; Mastectomy, Modified Radical; Middle Aged; Neoplasm Staging; Remission Induction; Risk Assessment; Tamoxifen; Tegafur; Time Factors; Treatment Outcome | 2006 |
Delayed leukoencephalopathy with stroke-like presentation in chemotherapy recipients.
Topics: Adult; Aged; Antineoplastic Agents; Brain; Brain Edema; Capecitabine; Dementia, Vascular; Deoxycytidine; Diffusion Magnetic Resonance Imaging; Energy Metabolism; Female; Fluorouracil; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Infusions, Intravenous; Injections, Spinal; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neoplasms; Nerve Fibers, Myelinated; Neurologic Examination; Registries; Remission, Spontaneous; Stroke; Tegafur | 2008 |
Immunochemotherapy with PSK and fluoropyrimidines improves long-term prognosis for curatively resected colorectal cancer.
Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Combined Modality Therapy; Drug Combinations; Female; Floxuridine; Fluorouracil; Humans; Immunotherapy; Kaplan-Meier Estimate; Male; Middle Aged; Prognosis; Proportional Hazards Models; Proteoglycans; Retrospective Studies; Tegafur; Uracil | 2008 |
Anti-tumor activity of carmofur water-solubilized by lactic acid oligomer-grafted pullulan nanogels.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Dimethyl Sulfoxide; Drug Screening Assays, Antitumor; Fluorouracil; Glucans; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Nanostructures; Solubility | 2009 |
Co-polymeric hydrophilic nanospheres for drug delivery: release kinetics, and cellular uptake.
Topics: Acrylamides; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Fluorouracil; Humans; Hydrophobic and Hydrophilic Interactions; Nanospheres; Polymers; Povidone | 2010 |
CEA fluctuation during a single fluorouracil-based chemotherapy cycle for metastatic colorectal cancer.
Topics: Adult; Aged; Biomarkers, Tumor; Carcinoembryonic Antigen; Colorectal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Quinazolines; Thiophenes; Tomography, X-Ray Computed | 2013 |
Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity.
Topics: Acid Ceramidase; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Ceramides; Drug Resistance, Multiple; Fluorouracil; Humans; Male; Mice; Neoplasms | 2013 |
Atom based 3D-QSAR studies on 2,4-dioxopyrimidine-1-carboxamide analogs: Validation of experimental inhibitory potencies towards acid ceramidase.
Topics: Acid Ceramidase; Fluorouracil; Humans; Models, Molecular; Quantitative Structure-Activity Relationship | 2016 |
Micrometastasis Volume in Lymph Nodes Determines Disease Recurrence Rate of Stage II Colorectal Cancer: A Prospective Multicenter Trial.
Topics: Aged; Antineoplastic Agents; Biomarkers, Tumor; Carcinoembryonic Antigen; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Lymph Nodes; Male; Middle Aged; Neoplasm Micrometastasis; Neoplasm Recurrence, Local; Prospective Studies; RNA, Messenger | 2016 |
Screening a Commercial Library of Pharmacologically Active Small Molecules against Staphylococcus aureus Biofilms.
Topics: Anti-Bacterial Agents; Auranofin; Biofilms; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Repositioning; Fluorouracil; High-Throughput Screening Assays; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Niclosamide; Small Molecule Libraries; Staphylococcus aureus | 2016 |
Electrosprayed Janus Particles for Combined Photo-Chemotherapy.
Topics: A549 Cells; Antineoplastic Agents; Fluorouracil; Humans; Particle Size; Pharmaceutic Aids; Photochemotherapy; Photosensitizing Agents; Povidone; Rose Bengal | 2017 |
Exchange of polar lipids from adults to neonates in Daphnia magna: Perturbations in sphingomyelin allocation by dietary lipids and environmental toxicants.
Topics: Animals; Atrazine; Daphnia; Dietary Fats; Fatty Acids, Unsaturated; Fertility; Fluorouracil; Gene Expression Regulation; Lipid Metabolism; Phosphatidylcholines; Sphingomyelins; Triclosan; Water Pollutants, Chemical | 2017 |
Light-driven liquid metal nanotransformers for biomedical theranostics.
Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Drug Liberation; Female; Fluorouracil; HeLa Cells; Humans; Infrared Rays; Lasers; Materials Testing; Metal Nanoparticles; Mice; Microfluidics; Models, Animal; Nanocapsules; Radiographic Image Enhancement; Radiography; Reactive Oxygen Species; Theranostic Nanomedicine | 2017 |
Pharmacological inhibition of pigmentation in Cryptococcus.
Topics: Antifungal Agents; Cryptococcus gattii; DNA Mutational Analysis; Drug Evaluation, Preclinical; Flucytosine; Fluorouracil; Genetic Testing; Melanins; Mutagenesis, Insertional | 2019 |
Toward stimulating apoptosis in human lung adenocarcinoma cells by novel nano-carmofur compound treatment.
Topics: A549 Cells; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Fluorouracil; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Nanoparticles | 2021 |
Molecular Mechanism of Inhibition of Acid Ceramidase by Carmofur.
Topics: Acid Ceramidase; Antineoplastic Agents; Binding Sites; Crystallography, X-Ray; Fluorouracil; Humans; Molecular Dynamics Simulation; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins | 2019 |
Facile Transfer of Reverse Micelles from the Organic to the Aqueous Phase for Mimicking Enzyme Catalysis and Imaging-Guided Cancer Therapy.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; A549 Cells; Antineoplastic Agents; Benzoin; Catalysis; Drug Carriers; Drug Liberation; Fluorescent Dyes; Fluorouracil; Gold; Humans; Metal Nanoparticles; Micelles; Neoplasms; Oxidation-Reduction; Rhodamines; Water | 2019 |
Control of lysosomal TRPML1 channel activity and exosome release by acid ceramidase in mouse podocytes.
Topics: Acid Ceramidase; Animals; Cell Line, Transformed; Exosomes; Fluorouracil; Lysosomes; Mice; Mice, Inbred C57BL; Podocytes; Transient Receptor Potential Channels | 2019 |
Electrospun oral formulations for combined photo-chemotherapy of colon cancer.
Topics: Acrylic Resins; Administration, Oral; Animals; Antineoplastic Agents; Caco-2 Cells; Cell Line; Cell Survival; Drug Carriers; Drug Combinations; Electrochemical Techniques; Fibroblasts; Fluorouracil; Humans; Hypromellose Derivatives; Intestine, Large; Light; Nanofibers; Organ Specificity; Photosensitizing Agents; Phototherapy; Rats, Sprague-Dawley; Rose Bengal; Tissue Culture Techniques | 2019 |
Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur.
Topics: Animals; Betacoronavirus; Chlorocebus aethiops; Coronavirus 3C Proteases; Coronavirus Infections; COVID-19; Cysteine Endopeptidases; Fluorouracil; Models, Molecular; Pandemics; Pneumonia, Viral; SARS-CoV-2; Vero Cells; Viral Nonstructural Proteins | 2020 |
pH-Responsive nanocomposite fibres allowing MRI monitoring of drug release.
Topics: Drug Carriers; Drug Liberation; Ferric Compounds; Fluorouracil; Hydrogen-Ion Concentration; Magnetic Resonance Imaging; Nanocomposites | 2020 |
N-acylsphingosine amidohydrolase 1 promotes melanoma growth and metastasis by suppressing peroxisome biogenesis-induced ROS production.
Topics: Acid Ceramidase; Animals; Carcinogenesis; Cell Line, Tumor; Ceramides; E2F1 Transcription Factor; Fluorouracil; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; MAP Kinase Signaling System; Melanoma; Mice, Nude; Neoplasm Metastasis; Peroxisomes; Reactive Oxygen Species; Skin Neoplasms; Transfection; Tumor Burden; Xenograft Model Antitumor Assays | 2021 |
The reproductive effects of the cancer chemotherapy agent, Carmofur, on Daphnia magna are mediated by its metabolite, 5-Fluorouracil.
Topics: Animals; Antineoplastic Agents; Daphnia; Fluorouracil; Neoplasms; Reproduction | 2022 |
Temperature/pH-responsive carmofur-loaded nanogels rapidly prepared via one-pot laser-induced emulsion polymerization.
Topics: Drug Carriers; Emulsions; Fluorouracil; Hydrogen-Ion Concentration; Lasers; Nanogels; Polymerization; Temperature | 2022 |
How Reproducible Are QM/MM Simulations? Lessons from Computational Studies of the Covalent Inhibition of the SARS-CoV-2 Main Protease by Carmofur.
Topics: Coronavirus 3C Proteases; COVID-19; Fluorouracil; Humans; Quantum Theory; Reproducibility of Results; SARS-CoV-2 | 2022 |