fluorouracil has been researched along with carbon tetrachloride in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Imai, S; Nio, Y; Ohgaki, K; Shiraishi, T; Tobe, T | 1 |
| Carlone, MF; King, SW; Magus, RD; Phillips, MW | 1 |
| Melvin, JB | 1 |
| Hobara, N; Watanabe, A | 1 |
| Bocci, G; Danesi, R; Del Tacca, M; Innocenti, F; Natale, G | 1 |
| Arimori, K; Hatakeyama, K; Hidaka, Y; Iwakiri, T; Kawano, Y; Nagata, M; Okumura, M | 1 |
| Cho, JH; Jeong, SH; Kang, HG; Kang, SJ; Kim, EJ; Park, SW; Park, YI; Shin, HS; Son, SW | 1 |
| Gao, L; Huo, X; Li, C; Sun, G; Wang, C | 1 |
12 other study(ies) available for fluorouracil and carbon tetrachloride
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
[Anti-tumor effect of fluoropyrimidines on human tumor cell lines transplanted in nude mice with CCl4-induced liver dysfunction].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carbon Tetrachloride; Cell Line; Colonic Neoplasms; Fluorouracil; Humans; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Stomach Neoplasms; Tegafur; Transplantation, Heterologous; Uracil | 1989 |
Enhancement by carbon tetrachloride treatment of hepatic tyrosine amino-transferase induction in the presence of net polyribosome breakdown in the rat.
Topics: Adrenal Glands; Adrenalectomy; Animals; Carbon Isotopes; Carbon Tetrachloride; Centrifugation, Density Gradient; Dactinomycin; Enzyme Induction; Fluorouracil; Hydrocortisone; Hypophysectomy; Kinetics; Liver; Male; Orotic Acid; Pituitary Gland; Rats; Ribosomes; RNA; Tryptophan Oxygenase; Tyrosine Transaminase | 1972 |
The effect of actinomycin D on mitosis in regenerating mouse liver.
Topics: Animals; Body Weight; Carbon Tetrachloride; Cell Division; Dactinomycin; Fluorouracil; Liver Regeneration; Male; Mice; Puromycin; Riboflavin; RNA; Sodium Chloride | 1967 |
Altered pharmacodynamics of 1-(2-tetrahydrofuryl)-5-fluorouracil by pretreatment of rats with phenobarbital, indomethacin, diclofenac sodium and carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Diclofenac; Female; Fluorouracil; Indomethacin; Microsomes, Liver; Phenobarbital; Phenylacetates; Rats; Tegafur; Time Factors | 1980 |
5-Fluorouracil catabolism to 5-fluoro-5,6-dihydrouracil is reduced by acute liver impairment in mice.
Topics: Animals; Antimetabolites, Antineoplastic; Area Under Curve; Carbon Tetrachloride; Female; Fluorouracil; Liver Diseases; Mice; Mice, Inbred ICR | 2005 |
Hepatic fibrosis does not affect the pharmacokinetics of 5-fluorouracil in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Area Under Curve; Carbon Tetrachloride; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Infusions, Intra-Arterial; Injections, Intravenous; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar | 2011 |
Evaluation of hepatotoxicity of chemicals using hepatic progenitor and hepatocyte-like cells derived from mouse embryonic stem cells: effect of chemicals on ESC-derived hepatocyte differentiation.
Topics: Animal Testing Alternatives; Animals; Arsanilic Acid; Biomarkers; Carbon Tetrachloride; Cell Differentiation; Cell Survival; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Embryonic Stem Cells; Fluorouracil; Hepatocytes; Mice; Toxicity Tests | 2013 |
Hepatoprotective Effect of Carboxymethyl Pachyman in Fluorouracil-Treated CT26-Bearing Mice.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Apoptosis; Aspartate Aminotransferases; Carbon Tetrachloride; Catalase; Cell Line; Colorectal Neoplasms; Fluorouracil; Glucans; Glutathione; Humans; Inflammation; Interleukin-1beta; Liver; Male; Mice, Inbred BALB C; NF-kappa B; NF-KappaB Inhibitor alpha; Protective Agents; Superoxide Dismutase | 2017 |