fluorouracil and bromouracil

fluorouracil has been researched along with bromouracil in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199033 (66.00)18.7374
1990's8 (16.00)18.2507
2000's5 (10.00)29.6817
2010's4 (8.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, MS; Prusoff, WH; Schinazi, RF1
Balzarini, J; Bentrude, WG; Béres, J; De Clercq, E; Kálmán, A; Párkányi, L1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Johnson, GA1
Simpson, LD; Zimbrick, JD1
Berech, J; Schoen, HF1
Crittenden, GC; Haugen, O; Prydz, S1
Ashida, N; Baba, M; Ikeda, T; Machida, H; Sakata, S; Shigeta, S1
Ghose, AK; Ghose, R; Singh, RK; Singh, SM; Singh, UP; Sodhi, A1
Arenaz, P; Seal, G; Sirover, MA1
Balzarini, J; Bricaud, H; De Clercq, E; Desgranges, C; Drouillet, F; Herdewijn, P; Razaka, G1
de Jong, AP; Kok, RM; Lankelma, J; Peters, GJ; van Groeningen, CJ1
Cihák, A; Veselỳ, J1
Bagshaw, MA; Goffinet, DR1
Bresler, SK; Mosevitskii, MI; Vyacheslavov, LG1
Beck, A; Tan, YL1
Schweiger, K; Streffer, C1
de Robichon-Szulmajster, H; Masselot, M1
Garrett, ER; Nolte, H1
Pedicelli, G1
Chan, A; Ewart, DF; Walker, IG1
Lohmann, W; Penka, V1
Painter, RB; Young, BR1
Marshak, A1
Deyrup, CL; Sander, EG1
Antonovskiĭ, VL; Gukovskaia, AS; Prokop'eva, TM; Sukhoroukov, BI1
Bansal, KM; Patterson, LK; Schuler, RH1
Bansal, KM; Patterson, LK1
Lukezic, FL; Miehle, BR1
Egawa, S1
Gulati, OD; Patel, DG1
Hüttermann, J1
Ausman, RK; Hamid, AA; Hoffman, NE; Quebbeman, EJ1
Bloom, LB; Eritja, R; Goodman, MF; Yu, H1
Danenberg, KD; Danenberg, PV; Horikoshi, T; Lenz, HJ; Schmittgen, TD1
Akimoto, S; Kataoka, K; Kinouchi, T; Matsuda, Y; Nakayama, H; Ohnishi, Y1
Allain, P; Boisdron-Celle, M; Gamelin, E; Larra, F; Robert, J; Turcant, A1
Kato, A; Ogura, K; Okuda, H; Takubo, H; Watabe, T1
Huels, MA; Klyachko, DV; Sanche, L1
Bellemann, ME; Brix, G; Haberkorn, U1
Ito, K; Kanamitsu, SI; Muro, K; Ogura, K; Okuda, H; Sugiyama, Y; Watabe, T1
Balzarini, J; Carangio, A; De Clercq, E; Esnouf, R; Liekens, S; McGuigan, C; Sienaert, R; Van Kuilenburg, A1
Nishiyama, T; Ogura, K; Watabe, T1
GEISSLER, E1
ROSENTHAL, HA1
Alauddin, MM; Conti, PS; Fissekis, JD; Park, R; Shahinian, A; Tohme, M1
Blanco-Bose, W; Bockamp, E; Dunant, CF; Eshkind, L; Jaworski, M; Laurenti, E; Lió, P; Macdonald, HR; Offner, S; Oser, G; Trumpp, A; van der Wath, RC; Wilson, A1
Cai, H; Conti, PS; Li, Z1
Basílio Janke, EM; Weisz, K1
Brown, A; Sun, S1

Reviews

4 review(s) available for fluorouracil and bromouracil

ArticleYear
Resistance of mammalian tumour cells toward pyrimidine analogues. A review.
    Oncology, 1973, Volume: 28, Issue:3

    Topics: Animals; Antimetabolites; Azacitidine; Azauridine; Bromouracil; Carcinoma, Ehrlich Tumor; Cell Line; Cricetinae; Cytarabine; Deoxycytidine; Drug Resistance; Fluorouracil; Genetic Code; Leukemia, Experimental; Leukemia, Lymphoid; Mast-Cell Sarcoma; Mice; Mutation; Neoplasms, Experimental; Oncogenic Viruses; Phosphotransferases; Pyrimidines; Sarcoma, Experimental; Selection, Genetic; Thymidine Kinase; Uracil; Virus Replication

1973
Clinical use of radiation sensitizing agents.
    Cancer treatment reviews, 1974, Volume: 1, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Bromodeoxycytidine; Bromodeoxyuridine; Bromouracil; Carcinoma, Squamous Cell; Dactinomycin; Dose-Response Relationship, Radiation; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Idoxuridine; Neoplasms; Neoplasms, Experimental; Radiation-Sensitizing Agents

1974
Solid-state radiation chemistry of DNA and its constituents.
    Ultramicroscopy, 1982, Volume: 10, Issue:1-2

    Topics: Bromouracil; Chemical Phenomena; Chemistry; Cold Temperature; DNA; DNA, Bacterial; Electron Spin Resonance Spectroscopy; Electrons; Fluorouracil; Free Radicals; Nucleosides; Nucleotides; Oxidation-Reduction; Purines; Pyrimidines; Uracil

1982
[Molecular toxicological mechanism of the lethal interactions of the new antiviral drug, sorivudine, with 5-fluorouracil prodrugs and genetic deficiency of dihydropyrimidine dehydrogenase].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2002, Volume: 122, Issue:8

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Drug Therapy, Combination; Fluorouracil; Humans; NADP; Oxidoreductases; Prodrugs; Rats

2002

Trials

1 trial(s) available for fluorouracil and bromouracil

ArticleYear
Prediction of in vivo drug-drug interactions based on mechanism-based inhibition from in vitro data: inhibition of 5-fluorouracil metabolism by (E)-5-(2-Bromovinyl)uracil.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:4

    Topics: Adult; Aged; Animals; Antimetabolites; Antiviral Agents; Area Under Curve; Blood Proteins; Blotting, Western; Bromouracil; Cytosol; Depression, Chemical; Drug Interactions; Female; Fluorouracil; Half-Life; Humans; Luminescent Measurements; Male; Middle Aged; Protein Binding; Rats

2000

Other Studies

45 other study(ies) available for fluorouracil and bromouracil

ArticleYear
Synthesis and biological activities of some uronic acids, uronates, uronamides, and urononitriles of pyrimidine nucleosides.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:11

    Topics: Animals; Cell Division; Cells, Cultured; Chick Embryo; Pyrimidine Nucleosides; Sarcoma 180; Simplexvirus; Streptococcus; Structure-Activity Relationship; Substrate Specificity; Thymidine Kinase; Thymidylate Synthase; Uronic Acids; Virus Replication

1978
Synthesis, structure, and antitumor and antiviral activities of a series of 5-halouridine cyclic 3',5'-monophosphates.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:4

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Humans; Leukemia L1210; Mice; Molecular Conformation; Nucleotides, Cyclic; Protein Kinases; Rabbits; Simplexvirus; Structure-Activity Relationship; Uracil Nucleotides; Uridine Monophosphate; Vaccinia virus; X-Ray Diffraction

1986
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Free radicals formed by exposure of pyrimidine solids to sodium atoms: an electron spin resonance study.
    Proceedings of the National Academy of Sciences of the United States of America, 1975, Volume: 72, Issue:3

    Topics: Alloxan; Bromouracil; Cytosine; Electron Spin Resonance Spectroscopy; Fluorouracil; Free Radicals; Pyrimidines; Sodium; Thymine; Uracil

1975
E.s.r. studies of halogenated pyrimidines in gamma-irradiated alkaline glasses.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1975, Volume: 28, Issue:5

    Topics: Bromouracil; Cobalt Radioisotopes; Dose-Response Relationship, Radiation; Electron Spin Resonance Spectroscopy; Fluorouracil; Free Radicals; Gamma Rays; Glass; Radiation Effects; Uracil

1975
Prevention of 5-fluorouracil-caused growth inhibition in Sordaria fimicola.
    Antimicrobial agents and chemotherapy, 1977, Volume: 11, Issue:2

    Topics: Ascomycota; Bromouracil; Culture Media; Fluorouracil; Xylariales

1977
Thermoluminescent properties of crystalline halogen substituted uracils.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1975, Volume: 27, Issue:5

    Topics: Bromouracil; Fluorouracil; Freezing; Hot Temperature; Luminescent Measurements; Radiation Effects; Ultraviolet Rays; Uracil; X-Rays

1975
In vitro drug combination of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil with anti-human immunodeficiency virus or anticancer nucleosides.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:1

    Topics: Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Cytarabine; Drug Combinations; Floxuridine; Fluorouracil; Herpesvirus 3, Human; HIV-1; Humans; Zidovudine

1992
The effect of histidine on the structure and antitumor activity of metal-5-halouracil complexes.
    Journal of inorganic biochemistry, 1989, Volume: 37, Issue:4

    Topics: Animals; Bromouracil; Cadmium; Cobalt; Copper; Fluorouracil; Histidine; Lymphoma; Magnetics; Manganese; Mice; Mice, Inbred C3H; Molecular Structure; Nickel; Spectrophotometry; Structure-Activity Relationship; Uracil; Zinc

1989
Purification and properties of the human placental uracil DNA glycosylase.
    Biochimica et biophysica acta, 1987, Aug-13, Volume: 925, Issue:2

    Topics: Antibodies, Monoclonal; Bromouracil; Chromatography; DNA Glycosylases; Enzyme-Linked Immunosorbent Assay; Fluorouracil; Hot Temperature; Humans; Molecular Weight; N-Glycosyl Hydrolases; Placenta; Uracil-DNA Glycosidase

1987
Effect of (E)-5-(2-bromovinyl)uracil on the catabolism and antitumor activity of 5-fluorouracil in rats and leukemic mice.
    Cancer research, 1986, Volume: 46, Issue:3

    Topics: Animals; Bromouracil; Dihydrouracil Dehydrogenase (NADP); Drug Synergism; Fluorouracil; Leukemia P388; Leukemia, Experimental; Liver; Metabolic Clearance Rate; Mice; Oxidoreductases; Pyrimidines; Rats; Thymidine; Thymine; Uracil

1986
Highly sensitive determination of 5-fluorouracil in human plasma by capillary gas chromatography and negative ion chemical ionization mass spectrometry.
    Journal of chromatography, 1985, Sep-13, Volume: 343, Issue:1

    Topics: Alkylation; Bromouracil; Colonic Neoplasms; Fluorouracil; Gas Chromatography-Mass Spectrometry; Humans; Rectal Neoplasms; Time Factors; Uracil

1985
Errors in DNA replication in bacteria in the presence of a thymidylic acid deficiency.
    Molecular biology, 1974, Volume: 8, Issue:2

    Topics: Bacillus subtilis; Bromouracil; Cell Survival; Deoxyribonucleosides; DNA Replication; Drug Resistance, Microbial; Escherichia coli; Fluorouracil; Glucose; Kinetics; Mathematics; Methyltransferases; Mutagens; Mutation; Probability; Species Specificity; Streptomycin; Thymidine; Thymidylate Synthase; Thymine; Time Factors; Tryptophan

1974
Complex formation of uracil, 2'-deoxyuridine and their 5-halogenated derivatives.
    Biochimica et biophysica acta, 1973, Apr-11, Volume: 299, Issue:4

    Topics: Bromodeoxyuridine; Bromouracil; Chemical Phenomena; Chemistry; Copper; Deoxyuridine; Drug Stability; Floxuridine; Fluorouracil; Idoxuridine; Mathematics; Nickel; Potentiometry; Silver; Uracil

1973
[Biochemical effect of certain radiation-sensitizing agents].
    Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1972

    Topics: Bromouracil; Dactinomycin; DNA; Enzyme Induction; Fluorouracil; Humans; Protein Biosynthesis; Puromycin; Radiation-Sensitizing Agents; RNA, Messenger; Uracil

1972
Methionine biosynthesis in Saccharomyces cerevisiae: mutations at the regulatory locus ETH2. I. Genetic data.
    Molecular & general genetics : MGG, 1974, Apr-03, Volume: 129, Issue:4

    Topics: Alleles; Bromouracil; Chromosome Mapping; Enzyme Repression; Ethionine; Fluorouracil; Genes, Regulator; Genetic Linkage; Mesylates; Methionine; Mutation; Phenotype; Saccharomyces cerevisiae

1974
Kinetics and mechanisms of drug action on microorganisms. XIV. The action of fluorouracil, other uracils and derived nucleosides on the microbial kinetics of Escherichia coli.
    Chemotherapy, 1972, Volume: 17, Issue:2

    Topics: Bromodeoxyuridine; Bromouracil; Chlorine; Culture Media; Deoxyribonucleosides; Escherichia coli; Fluorouracil; Hydrogen-Ion Concentration; Kinetics; Nucleosides; Osmolar Concentration; Protein Binding; Time Factors; Uracil

1972
[Radiosensitizing chemical agents. Radiobiological reasons and prospects for their use].
    Minerva medica, 1972, Volume: 63, Issue:7

    Topics: Acetates; Animals; Bromodeoxyuridine; Bromouracil; Carcinoma, Ehrlich Tumor; Cell Membrane; Cosmic Radiation; DNA; Fluorouracil; Iodine; Mice; Naphthoquinones; Pyrimidines; Radiation Effects; Radiation-Sensitizing Agents; Radiotherapy Dosage

1972
Isolation of the bromouracil-substituted light strand of mouse satellite DNA.
    Canadian journal of biochemistry, 1973, Volume: 51, Issue:1

    Topics: Animals; Bromouracil; Centrifugation, Density Gradient; Cesium; Chlorides; Chromatography; DNA; Fluorouracil; L Cells; Mice; Nucleotides; Phosphorus Isotopes; Tritium; Uracil

1973
Influence of metal ions on systems of dimethylsulfoxide-uracil-derivatives: NMR investigations.
    Biophysik, 1973, Volume: 10, Issue:3

    Topics: Barbiturates; Bromouracil; Cobalt; Copper; Deuterium; Dimethyl Sulfoxide; Fluorouracil; Ions; Iron; Ligands; Magnetic Resonance Spectroscopy; Metals; Nickel; Silver; Thiouracil; Uracil; Zinc

1973
Repair replication induced by 3H incorporated into HeLa DNA.
    Mutation research, 1974, Volume: 22, Issue:2

    Topics: Bromouracil; Centrifugation, Density Gradient; Culture Media; DNA Repair; DNA Replication; DNA, Neoplasm; Fluorouracil; HeLa Cells; Humans; In Vitro Techniques; Iodine Radioisotopes; Thymidine; Tritium; Uracil

1974
Distribution of topically applied compounds in relation to therapy of skin cancer.
    American journal of clinical pathology, 1972, Volume: 57, Issue:1

    Topics: Autoradiography; Bromouracil; Carbon Isotopes; Fluorouracil; Humans; Intercellular Junctions; Skin Absorption; Skin Neoplasms

1972
The effect of bisulfite on the dehalogenation of 5-chloro-, 5-bromo-, and 5-iodouracil.
    Archives of biochemistry and biophysics, 1972, Volume: 150, Issue:2

    Topics: Bromouracil; Chemical Phenomena; Chemistry; Chlorine; Fluorouracil; Iodine; Kinetics; Magnetic Resonance Spectroscopy; Spectrophotometry; Sulfites; Sulfonic Acids; Ultraviolet Rays; Uracil

1972
[Protonation of thymine, uracil and its 5-haloid-derivatives].
    Doklady Akademii nauk SSSR, 1972, Jul-11, Volume: 205, Issue:2

    Topics: Bromouracil; Fluorouracil; Protons; Thymine; Uracil

1972
The production of halide ion in the radiolysis of aqueous solutions of the 5-halouracils.
    The Journal of physical chemistry, 1972, Aug-17, Volume: 76, Issue:17

    Topics: Bromouracil; Conductometry; Fluorouracil; Radiochemistry; Salts; Uracil

1972
Pulse radiolysis studies of 5-halouracils in aqueous solutions.
    The Journal of physical chemistry, 1972, Aug-17, Volume: 76, Issue:17

    Topics: Bromouracil; Chlorine; Fluorouracil; Kinetics; Radiochemistry; Spectrum Analysis; Ultraviolet Rays; Uracil

1972
Studies on conidial germination and appressorium formation by Colletotrichum trifolii Bain & Essary.
    Canadian journal of microbiology, 1972, Volume: 18, Issue:8

    Topics: Atmosphere; Bromouracil; Carbon Dioxide; Cycloheximide; Dactinomycin; Fluorine; Fluorouracil; Fungi; Mitosporic Fungi; Phenylalanine; Spores; Spores, Fungal; Surface-Active Agents; Temperature

1972
[RRadiotherapy and radio-sensitizing agents].
    Rinsho hoshasen. Clinical radiography, 1971, Volume: 16, Issue:12

    Topics: Bromouracil; Fluorouracil; Humans; Maxillary Neoplasms; Radiation-Sensitizing Agents; Radiotherapy

1971
Effects of various drugs on insulin antibodies.
    British journal of pharmacology, 1971, Volume: 42, Issue:1

    Topics: Animals; Antibodies; Antineoplastic Agents; Bromouracil; Chlorambucil; Chlorpropamide; Complement Fixation Tests; Cyclophosphamide; Dactinomycin; Diaphragm; Diethylstilbestrol; Drug Synergism; Female; Fluorouracil; Gonadal Steroid Hormones; Guinea Pigs; Hydrocortisone; Injections, Intraperitoneal; Injections, Subcutaneous; Insulin Antibodies; Male; Mercaptopurine; Methotrexate; Neutralization Tests; Phenformin; Testosterone; Tolbutamide; Triazines

1971
Stability of fluorouracil in plastic containers used for continuous infusion at home.
    American journal of hospital pharmacy, 1984, Volume: 41, Issue:6

    Topics: Bromouracil; Chromatography, High Pressure Liquid; Drug Packaging; Drug Stability; Fluorouracil; Home Care Services; Hot Temperature; Infusions, Parenteral; Plastics; Spectrophotometry, Ultraviolet; Time Factors

1984
Ionization of bromouracil and fluorouracil stimulates base mispairing frequencies with guanine.
    The Journal of biological chemistry, 1993, Jul-25, Volume: 268, Issue:21

    Topics: Base Sequence; Bromodeoxyuridine; Bromouracil; DNA; Floxuridine; Fluorouracil; Guanine; Hydrogen Bonding; Hydrogen-Ion Concentration; Ions; Molecular Sequence Data; Nucleic Acid Heteroduplexes; RNA-Directed DNA Polymerase; Templates, Genetic; Thymine Nucleotides

1993
Effect of 5-fluoro- and 5-bromouracil substitution on the translation of human thymidylate synthase mRNA.
    The Journal of biological chemistry, 1994, Jun-10, Volume: 269, Issue:23

    Topics: Base Sequence; Bromouracil; Cell-Free System; Fluorouracil; Humans; Kinetics; Molecular Sequence Data; Protein Biosynthesis; Reticulocytes; RNA, Messenger; Structure-Activity Relationship; Thymidylate Synthase; Transcription, Genetic

1994
Intestinal anaerobic bacteria hydrolyse sorivudine, producing the high blood concentration of 5-(E)-(2-bromovinyl)uracil that increases the level and toxicity of 5-fluorouracil.
    Pharmacogenetics, 1997, Volume: 7, Issue:1

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Bacteria, Anaerobic; Bacteroides; Biotransformation; Bromouracil; Cecum; Fluorouracil; Gastric Mucosa; Gastrointestinal Contents; Intestinal Mucosa; Kidney; Liver; Male; Organ Specificity; Pentosyltransferases; Pyrimidine Phosphorylases; Rats; Rats, Sprague-Dawley

1997
Rapid and sensitive high-performance liquid chromatographic analysis of halogenopyrimidines in plasma.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Aug-01, Volume: 695, Issue:2

    Topics: 5-Methylcytosine; Antimetabolites, Antineoplastic; Bromouracil; Chromatography, High Pressure Liquid; Cytosine; Flucytosine; Fluorouracil; Humans; Hydrogen-Ion Concentration; Osmolar Concentration; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Uracil

1997
A possible mechanism of eighteen patient deaths caused by interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Cause of Death; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Fluorouracil; Half-Life; Herpes Zoster; Humans; Liver; Neoplasms; Oxidoreductases; Prodrugs; Rats; Tissue Distribution

1998
Halogen anion formation in 5-halouracil films: X rays compared to subionization electrons.
    Radiation research, 1999, Volume: 151, Issue:2

    Topics: Anions; Bromouracil; Chemical Phenomena; Chemistry, Physical; Electrons; Fluorouracil; Radiation-Sensitizing Agents; Uracil; X-Rays

1999
Biochemical modulation of the catabolism and tissue uptake of the anticancer drug 5-fluorouracil by 5-bromovinyluracil: assessment with metabolic (19)F MR imaging.
    Magnetic resonance in medicine, 1999, Volume: 42, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; beta-Alanine; Biotransformation; Bromouracil; Cell Division; Dose-Response Relationship, Drug; Fluorouracil; Immunologic Factors; Liver; Liver Neoplasms, Experimental; Magnetic Resonance Imaging; Male; Muscle, Skeletal; Neoplasm Transplantation; Rats; Rats, Inbred ACI; Tissue Distribution; Tumor Cells, Cultured

1999
Lack of susceptibility of bicyclic nucleoside analogs, highly potent inhibitors of varicella-zoster virus, to the catabolic action of thymidine phosphorylase and dihydropyrimidine dehydrogenase.
    Molecular pharmacology, 2002, Volume: 61, Issue:5

    Topics: Animals; Antiviral Agents; Binding Sites; Bromodeoxyuridine; Bromouracil; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Escherichia coli; Fluorouracil; Herpesvirus 3, Human; Heterocyclic Compounds, 2-Ring; Humans; Mice; Models, Molecular; Nucleosides; Oxidoreductases; Substrate Specificity; Thymidine Phosphorylase

2002
[Studies on the mechanism of induction. IV. The effect of 5-bromouracil on induction with 5-fluorouracil and 5-fluorodeoxyuridine].
    Acta biologica et medica Germanica, 1963, Volume: 10

    Topics: Bromouracil; Coliphages; Escherichia coli; Floxuridine; Fluorouracil; Uracil

1963
[ON THE EFFECT OF 5-BROMOURACIL AND 5-FLUOROURACIL ON THE VIRUS INDUCTION OF A LYSOGENIC THYMINE-LESS MUTANT OF E. COLI BY MEANS OF ULTRAVIOLET RAYS].
    Acta biologica et medica Germanica, 1964, Volume: 13

    Topics: Bromouracil; Coliphages; DNA; Escherichia coli; Fluorouracil; Lysogeny; Research; Thymine; Ultraviolet Rays; Uracil; Virus Activation

1964
Synthesis of 2'-deoxy-2'-[18F]fluoro-5-bromo-1-beta-D-arabinofuranosyluracil ([18F]-FBAU) and 2'-deoxy-2'-[18F]fluoro-5-chloro-1-beta-D-arabinofuranosyl-uracil ([18F]-FCAU), and their biological evaluation as markers for gene expression.
    Nuclear medicine and biology, 2004, Volume: 31, Issue:4

    Topics: Animals; Arabinofuranosyluracil; Biomarkers, Tumor; Bromouracil; Colonic Neoplasms; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Markers; Humans; Isotope Labeling; Metabolic Clearance Rate; Mice; Mice, Nude; Organ Specificity; Radioisotope Dilution Technique; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Thymidine Kinase; Tissue Distribution; Tomography, Emission-Computed; Viral Proteins

2004
Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair.
    Cell, 2008, Dec-12, Volume: 135, Issue:6

    Topics: Adult Stem Cells; Animals; Antigens, Differentiation; Bone Marrow; Bromouracil; Fluorouracil; Green Fluorescent Proteins; Hematopoietic Stem Cells; Homeostasis; Mice; Mice, Transgenic; Uridine

2008
The improved syntheses of 5-substituted 2'-[18F]fluoro-2'-deoxy-arabinofuranosyluracil derivatives ([18F]FAU, [18F]FEAU, [18F]FFAU, [18F]FCAU, [18F]FBAU and [18F]FIAU) using a multistep one-pot strategy.
    Nuclear medicine and biology, 2011, Volume: 38, Issue:5

    Topics: Arabinofuranosyluracil; Bromouracil; Fluorouracil; Radiochemistry; Reference Standards

2011
Low-temperature NMR studies on the geometry of base pairs involving 5-substituted uracil derivatives.
    The journal of physical chemistry. B, 2013, May-02, Volume: 117, Issue:17

    Topics: Adenosine; Base Pairing; Bromouracil; Cold Temperature; Fluorouracil; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Thymidine; Uracil; Uridine

2013
Simulation of the resonance Raman spectra for 5-halogenated (F, Cl, and Br) uracils.
    The journal of physical chemistry. A, 2015, Apr-30, Volume: 119, Issue:17

    Topics: Bromouracil; Fluorouracil; Molecular Structure; Quantum Theory; Spectrum Analysis, Raman; Uracil

2015