fluorouracil has been researched along with apigenin in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 8 (36.36) | 29.6817 |
| 2010's | 9 (40.91) | 24.3611 |
| 2020's | 4 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Banskota, AH; Kadota, S; Matsushige, K; Midorikawa, K; Tezuka, Y; Usia, T | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Chiang, LC; Kuo, PL; Lin, CC; Lin, IC; Ng, LT | 1 |
| Ha, JH; Kim, DH; Lee, IK; Lee, JT | 1 |
| Ahn, BC; Ahn, SJ; Ha, JH; Lee, HW; Lee, JT; Lee, MG; Lee, SW; Lee, YJ; Lee, YL; Yoo, J | 1 |
| Chan, JY; Lee, SC; Tan, BK | 1 |
| Choi, EJ; Kim, GH | 1 |
| Alp, E; Konac, E; Menevse, S; Onen, HI; Turktekin, M; Yilmaz, A | 1 |
| Chan, LP; Chen, PR; Chiang, FY; Chou, TH; Ding, HY; Kuo, PL; Liang, CH | 1 |
| Fei, C; Jinlong, Y; Qiang, L; Yanping, L; Zhou, L; Zonghai, H | 1 |
| Gonzalez de Mejia, E; Johnson, JL | 1 |
| Guo, XJ; Guo, YB; Hu, XY; Liang, JY; Liu, L | 1 |
| Amaral Mendes, R; Gómez Garcia, F; Lopez-Jornet, P; Martinez Diaz, F; Molina Prats, P | 1 |
| Gaballah, HH; Gaber, RA; Mohamed, DA | 1 |
| Banerjee, S; Mandal, M; Sen, K | 1 |
| Choi, J; Hwang, S; Lim, W; Song, G; Song, J; Yang, C | 1 |
| Abalo, R; Capasso, R; Entrialgo-Cadierno, R; Fernández, J; Lombó, F; Silván, B; Uranga, JA; Villar, CJ | 1 |
| Butnariu, M; Calina, D; Cho, WC; Hossain, R; Islam, MS; Islam, MT; Khalipha, ABR; Khan, RA; Martorell, M; Ray, P; Sarkar, C; Sharifi-Rad, J; Umbetova, A | 1 |
| Boehme, LF; Fliegert, R; Gaida, MM; Ghadban, T; Giannou, A; Giese, N; Goetz, MR; Güngör, C; Hackert, T; Hausen, A; Heinrich, S; Izbicki, JR; Nitschke, C; Niv, MY; Reeh, M; Stern, L; Zhang, T | 1 |
| Bartel, J; Clemens-Schutjer, D; Fidler, P; Hayes, DL; Lee, JK; Leitch, JM; Loprinzi, CL; Michalak, JC; Novotny, P; O'Fallon, JR | 1 |
| Carrard, VC; Curra, M; Lauxen, IS; Martins, MA; Martins, MD; Pavesi, VC; Pellicioli, AC; Sant'Ana Filho, M | 1 |
1 review(s) available for fluorouracil and apigenin
| Article | Year |
|---|---|
Antiproliferative and palliative activity of flavonoids in colorectal cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apigenin; Cell Proliferation; Colorectal Neoplasms; Drug Synergism; Flavanones; Flavonoids; Fluorouracil; HCT116 Cells; HT29 Cells; Humans; Luteolin; Palliative Care; Propiophenones | 2021 |
1 trial(s) available for fluorouracil and apigenin
| Article | Year |
|---|---|
Prospective evaluation of a chamomile mouthwash for prevention of 5-FU-induced oral mucositis.
Topics: Antimetabolites, Antineoplastic; Chamomile; Double-Blind Method; Female; Flavonoids; Fluorouracil; Humans; Male; Middle Aged; Mouthwashes; Oils, Volatile; Plants, Medicinal; Stomatitis | 1996 |
20 other study(ies) available for fluorouracil and apigenin
| Article | Year |
|---|---|
Constituents of Chinese propolis and their antiproliferative activities.
Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Caffeic Acids; China; Chromatography, Thin Layer; Colonic Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; Free Radical Scavengers; Mice; Molecular Structure; Phenylethyl Alcohol; Picrates; Propolis; Spectrophotometry, Infrared; Tumor Cells, Cultured | 2002 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Anti-proliferative effect of apigenin and its apoptotic induction in human Hep G2 cells.
Topics: Animals; Antineoplastic Agents; Apigenin; Apoptosis; Cell Line; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; DNA Fragmentation; Fluorouracil; Humans; Liver; Mice; Tumor Suppressor Protein p53 | 2006 |
Comparative anticancer effects of flavonoids and diazepam in cultured cancer cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apigenin; Cell Line, Tumor; Cell Survival; Diazepam; Drug Screening Assays, Antitumor; Fatty Acid Synthases; Fatty Acid Synthesis Inhibitors; Flavonoids; Flavonols; Fluorouracil; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypnotics and Sedatives; Isoquinolines; Lovastatin; Vascular Endothelial Growth Factor A | 2008 |
In vitro antiproliferative characteristics of flavonoids and diazepam on SNU-C4 colorectal adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Apigenin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Diazepam; Drug Screening Assays, Antitumor; Drug Synergism; Flavonoids; Flavonols; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Hypnotics and Sedatives; Inhibitory Concentration 50; RNA, Messenger | 2009 |
Scutellarin sensitizes drug-evoked colon cancer cell apoptosis through enhanced caspase-6 activation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apigenin; Apoptosis; Blotting, Western; Caspase 6; Colonic Neoplasms; Drug Therapy, Combination; Enzyme Activation; Fluorouracil; Glucuronates; Humans; Resveratrol; Stilbenes; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2009 |
5-Fluorouracil combined with apigenin enhances anticancer activity through induction of apoptosis in human breast cancer MDA-MB-453 cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apigenin; Apoptosis; Breast Neoplasms; Caspase 3; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; Humans; Inhibitory Concentration 50; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2 | 2009 |
Evaluation of the effects of the flavonoid apigenin on apoptotic pathway gene expression on the colon cancer cell line (HT29).
Topics: Anticarcinogenic Agents; Apigenin; Apoptosis; Caspase 3; Caspase 8; Cell Cycle Checkpoints; Cyclin D1; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Synergism; Fluorouracil; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; L-Lactate Dehydrogenase; Microscopy, Fluorescence; RNA, Messenger; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2011 |
Apigenin induces apoptosis via tumor necrosis factor receptor- and Bcl-2-mediated pathway and enhances susceptibility of head and neck squamous cell carcinoma to 5-fluorouracil and cisplatin.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apigenin; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Caspases; Cell Cycle Checkpoints; Cell Survival; Cells, Cultured; Cisplatin; Drug Synergism; Flow Cytometry; Fluorouracil; Head and Neck Neoplasms; Humans; Lipid Peroxidation; Liver; Melanoma; Mice; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Neoplasms; Squamous Cell Carcinoma of Head and Neck; TNF-Related Apoptosis-Inducing Ligand | 2012 |
Study of the mechanism of bystander effect of KDR-CDglyTK system mediated by adenovirus for the treatment of gastric cancer.
Topics: Adenoviridae; Antimetabolites, Antineoplastic; Antiviral Agents; Apigenin; Bystander Effect; Cell Communication; Cell Line, Tumor; Cell Survival; Fluorescence Recovery After Photobleaching; Fluorouracil; Ganciclovir; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; HeLa Cells; Humans; Promoter Regions, Genetic; Stomach Neoplasms; Transfection | 2013 |
Interactions between dietary flavonoids apigenin or luteolin and chemotherapeutic drugs to potentiate anti-proliferative effect on human pancreatic cancer cells, in vitro.
Topics: Antineoplastic Agents; Apigenin; Apoptosis; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Synergism; Fluorouracil; Gemcitabine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Luteolin; Pancreatic Neoplasms; Signal Transduction; Transcription Factor RelA | 2013 |
5-Fluorouracil combined with apigenin enhances anticancer activity through mitochondrial membrane potential (ΔΨm)-mediated apoptosis in hepatocellular carcinoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apigenin; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Drug Synergism; Fluorouracil; Humans; Liver Neoplasms; Male; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Mitochondria; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Xenograft Model Antitumor Assays | 2015 |
The therapeutic effects of apigenin and dexamethasone on 5-fluorouracil-induced oral mucositis - a pilot study using a Syrian hamster model.
Topics: Animals; Anti-Inflammatory Agents; Apigenin; Dexamethasone; Disease Models, Animal; Fluorouracil; Male; Mesocricetus; Pilot Projects; Stomatitis | 2017 |
Apigenin potentiates the antitumor activity of 5-FU on solid Ehrlich carcinoma: Crosstalk between apoptotic and JNK-mediated autophagic cell death platforms.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apigenin; Apoptosis; Carcinoma, Ehrlich Tumor; Cell Death; Drug Synergism; Fluorouracil; Ki-67 Antigen; Male; MAP Kinase Kinase 4; Mice; Myeloid Cell Leukemia Sequence 1 Protein; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
Dual drug loaded liposome bearing apigenin and 5-Fluorouracil for synergistic therapeutic efficacy in colorectal cancer.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apigenin; Cell Cycle; Cell Proliferation; Chorioallantoic Membrane; Colorectal Neoplasms; Drug Carriers; Drug Synergism; Fluorouracil; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liposomes; Mice; Mice, Nude; NIH 3T3 Cells; TOR Serine-Threonine Kinases; Tumor Burden; Xenograft Model Antitumor Assays | 2019 |
Apigenin enhances apoptosis induction by 5-fluorouracil through regulation of thymidylate synthase in colorectal cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apigenin; Apoptosis; Colorectal Neoplasms; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; Humans; Thymidylate Synthase | 2021 |
Natural Compounds or Their Derivatives against Breast Cancer: A Computational Study.
Topics: Apigenin; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Citrinin; Curcumin; Female; Fluorouracil; Genes, BRCA1; Genetic Predisposition to Disease; Germ-Line Mutation; Humans; Molecular Docking Simulation | 2022 |
Potential role of the bitter taste receptor T2R14 in the prolonged survival and enhanced chemoresponsiveness induced by apigenin.
Topics: Apigenin; Fluorouracil; Humans; Receptors, G-Protein-Coupled; Signal Transduction; Taste | 2023 |
Effect of topical chamomile on immunohistochemical levels of IL-1β and TNF-α in 5-fluorouracil-induced oral mucositis in hamsters.
Topics: Administration, Topical; Animals; Antimetabolites, Antineoplastic; Chamomile; Cricetinae; Female; Fluorouracil; Immunohistochemistry; Interleukin-1beta; Stomatitis; Tumor Necrosis Factor-alpha | 2013 |