fluorouracil and alendronate

fluorouracil has been researched along with alendronate in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Goltz, D; Jauch, C; Schott, H; Schott, TC; Schwendener, RA1
Fehm, T; Kootz, B; Neubauer, H; Schott, S; Seeger, H; Wallwiener, M1
Königsrainer, A; Königsrainer, I; Küper, M; Schott, H; Schott, TC; Weinreich, J1
Busch, C; Noor, S; Schem, C; Schott, S; Tiwari, S; Tower, RJ; Vallet, S1
Campbell, GM; Damm, T; Desel, C; Fuchs, S; Glüer, CC; Heilmann, T; Kneissl, P; Rambow, AC; Schem, C; Schott, S; Tiwari, S; Tower, RJ; Trauzold, A; Zuhayra, M1
de Almeida, JM; Ervolino, E; Fiorin, LG; Furquim, EMA; Matheus, HR; Novaes, VCN; Oliveira, FLP; Piovezan, BR1

Reviews

1 review(s) available for fluorouracil and alendronate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

7 other study(ies) available for fluorouracil and alendronate

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
N⁴-[Alkyl-(hydroxyphosphono)phosphonate]-cytidine-new drugs covalently linking antimetabolites (5-FdU, araU or AZT) with bone-targeting bisphosphonates (alendronate or pamidronate).
    Bioorganic & medicinal chemistry, 2011, Jun-01, Volume: 19, Issue:11

    Topics: Alendronate; Animals; Antimetabolites, Antineoplastic; Arabinofuranosyluracil; Bone and Bones; Bone Density Conservation Agents; Cell Line, Tumor; Cytidine; Diphosphonates; Drug Screening Assays, Antitumor; Durapatite; Fluorouracil; Humans; Macrophages; Mice; Pamidronate; Uridine; Zidovudine

2011
Cytotoxicity of the new antimetabolite-bisphosphonate (5-FdU-alendronate) in comparison to standard therapeutics on breast and ovarian cancer cell lines in the ATP tumor chemosensitivity assay.
    Investigational new drugs, 2012, Volume: 30, Issue:4

    Topics: Adenosine Triphosphate; Alendronate; Antimetabolites, Antineoplastic; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Diphosphonates; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Imidazoles; Inhibitory Concentration 50; Ovarian Neoplasms; Reference Standards; Zoledronic Acid

2012
Cytostatic activity of a 5-fluoro-2'-deoxyuridine-alendronate conjugate against gastric adenocarcinoma and non-malignant intestinal and fibroblast cell lines.
    Anticancer research, 2012, Volume: 32, Issue:10

    Topics: Adenocarcinoma; Alendronate; Bone Density Conservation Agents; Bone Neoplasms; Cell Line; Cell Line, Tumor; Cytostatic Agents; Drug Resistance, Neoplasm; Fibroblasts; Fluorouracil; Humans; Intestines; Stomach Neoplasms

2012
In vitro and in vivo toxicity of 5-FdU-alendronate, a novel cytotoxic bone-seeking duplex drug against bone metastasis.
    Investigational new drugs, 2015, Volume: 33, Issue:4

    Topics: Alendronate; Animals; Antimetabolites, Antineoplastic; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Survival; Chick Embryo; Drug Combinations; Female; Fluorouracil; Glomerular Filtration Rate; Humans; Kidney; Mice, Nude; Osteoclasts

2015
Pharmacologically Inactive Bisphosphonates as an Alternative Strategy for Targeting Osteoclasts: In Vivo Assessment of 5-Fluorodeoxyuridine-Alendronate in a Preclinical Model of Breast Cancer Bone Metastases.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2017, Volume: 32, Issue:3

    Topics: Alendronate; Animals; Apoptosis; Biomarkers, Tumor; Bone Neoplasms; Bone Resorption; Caspases; Cell Cycle; Cell Line, Tumor; Diphosphonates; Female; Fluorouracil; Humans; Mammary Neoplasms, Animal; Mass Spectrometry; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteogenesis; Protein Prenylation; rap1 GTP-Binding Proteins; RAW 264.7 Cells; Xenograft Model Antitumor Assays

2017
Sodium alendronate is an effective adjunctive therapy for treating periodontitis in male rats treated with anticancer chemotherapy.
    Archives of oral biology, 2023, Volume: 155

    Topics: Alendronate; Alveolar Bone Loss; Animals; Dental Scaling; Fluorouracil; Male; Osteocalcin; Periodontitis; Rats; Rats, Wistar; Sodium

2023