fluorouracil has been researched along with acyclovir in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 11 (42.31) | 29.6817 |
| 2010's | 12 (46.15) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Allen, TM; Knaus, EE; Kumar, R; Tovell, DR; Tyrrell, DL; Wiebe, LI; Xu, LH | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Cordeiro, MN; Fernández, F; García-Mera, X; Helguera, AM; Rodríguez-Borges, JE | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Agrofoglio, LA; Andrei, G; Balzarini, J; Montagu, A; Roy, V; Snoeck, R | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Andrei, G; Kokosza, K; Piotrowska, DG; Schols, D; Snoeck, R | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Cargnin, S; Genazzani, AA; Massarotti, A; Pirali, T; Serafini, M | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Fickenscher, H; Hiller, C; Slavin, S; Wittmann, S | 1 |
| Olsen, BA | 1 |
| Iwaki, M; Ogiso, T; Okajima, K; Shiraki, T; Tanino, T; Wada, T | 1 |
| Amrikachi, M; Hsu, S; Woodruff, CA | 1 |
| Aldunate-Calvo, S; García-Montesinos-De la Peña, M; Gómez-Sánchez, MJ; Oteiza-López, L; Sáenz-Bañuelos, JJ; Tihista-Jiménez, JA | 1 |
| Arnold, RD; Chavre, S; Chu, CK; De, C; Hagen, FK; Liu, D; Moffat, JF; Singh, US; White, C; Zheng, B | 1 |
| Imoto, H; Kiyozaki, H; Obitsu, T; Rikiyama, T; Saito, M; Takata, O; Taniyama, Y | 1 |
| Battistelli, S; Benedetti, S; Canonico, B; Catalani, S; Galati, R; Luchetti, F; Palma, F; Papa, S | 1 |
2 review(s) available for fluorouracil and acyclovir
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Essential Medicinal Chemistry of Essential Medicines.
Topics: Administration, Oral; Chemistry, Pharmaceutical; Drugs, Essential; Formularies as Topic; Humans; Injections; Molecular Structure; Stereoisomerism; World Health Organization | 2020 |
24 other study(ies) available for fluorouracil and acyclovir
| Article | Year |
|---|---|
Synthesis and antiviral and cytotoxic activity of iodohydrin and iodomethoxy derivatives of 5-vinyl-2'-deoxyuridines, 2'-fluoro-2'-deoxyuridine, and uridine.
Topics: Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Biological Transport; Cell Survival; Chemical Phenomena; Chemistry; Deoxyuridine; In Vitro Techniques; Leukemia L1210; Leukemia P388; Mice; Tumor Cells, Cultured; Uridine; Vinyl Compounds | 1990 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Probing the anticancer activity of nucleoside analogues: a QSAR model approach using an internally consistent training set.
Topics: Algorithms; Antineoplastic Agents; Databases, Factual; Discriminant Analysis; Models, Molecular; Nucleosides; Quantitative Structure-Activity Relationship | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Synthesis of new C5-(1-substituted-1,2,3-triazol-4 or 5-yl)-2'-deoxyuridines and their antiviral evaluation.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Proliferation; Cells, Cultured; Chlorocebus aethiops; Cyclization; Deoxyuridine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Mice; Microbial Sensitivity Tests; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship; T-Lymphocytes; Vero Cells; Viruses | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Design, antiviral and cytostatic properties of isoxazolidine-containing amonafide analogues.
Topics: Acrylamides; Adenine; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Survival; Cycloaddition Reaction; Cytomegalovirus; Cytostatic Agents; Drug Design; Enterovirus; Humans; Isoxazoles; Naphthalimides; Nitrogen Oxides; Organophosphonates; Phlebovirus; Simplexvirus; Structure-Activity Relationship; Vaccinia virus | 2015 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Functional long-term thymidine kinase suicide gene expression in human T cells using a herpesvirus saimiri vector.
Topics: Acyclovir; Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Cells, Cultured; Fluorouracil; Ganciclovir; Gene Expression; Genetic Therapy; Genetic Vectors; Herpesvirus 2, Saimiriine; Humans; Recombination, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Saguinus; T-Lymphocytes; Thymidine Kinase; Transgenes | 2000 |
Hydrophilic interaction chromatography using amino and silica columns for the determination of polar pharmaceuticals and impurities.
Topics: Acetamides; Acyclovir; Amines; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Flucytosine; Fluorouracil; Guanine; Molecular Weight; Pharmaceutical Preparations; Sensitivity and Specificity; Silicon Dioxide | 2001 |
Transfollicular drug delivery: penetration of drugs through human scalp skin and comparison of penetration between scalp and abdominal skins in vitro.
Topics: Abdomen; Acyclovir; Administration, Cutaneous; Adult; Drug Delivery Systems; Female; Fluorouracil; Hair Follicle; Humans; In Vitro Techniques; Ketoprofen; Male; Melatonin; Middle Aged; Scalp; Skin Absorption | 2002 |
Zosteriform metastatic transitional cell carcinoma.
Topics: Acyclovir; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Drug Eruptions; Female; Fluorouracil; Humans; Interferons; Middle Aged; Urinary Bladder Neoplasms | 2005 |
[Herpes simplex virus bronchopneumonitis in patient with acute respiratory failure after surgery].
Topics: Acute Disease; Acyclovir; Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antiviral Agents; Bronchoalveolar Lavage Fluid; Bronchopneumonia; Combined Modality Therapy; Diagnosis, Differential; Female; Fluorouracil; Herpes Simplex; Humans; Immunocompromised Host; Pneumonia, Aspiration; Pneumonia, Viral; Postoperative Complications; Radiotherapy, Adjuvant; Rectal Neoplasms; Respiration, Artificial; Respiratory Insufficiency | 2010 |
β-l-1-[5-(E-2-bromovinyl)-2-(hydroxymethyl)-1,3-(dioxolan-4-yl)] uracil (l-BHDU) prevents varicella-zoster virus replication in a SCID-Hu mouse model and does not interfere with 5-fluorouracil catabolism.
Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Chickenpox; Dioxolanes; Drug Therapy, Combination; Fluorouracil; Foscarnet; Herpes Zoster; Herpesvirus 3, Human; Humans; Mice; Mice, Inbred BALB C; Mice, SCID; Nucleosides; Organ Culture Techniques; Skin; Uracil; Virus Replication | 2014 |
Herpes simplex virus-1 encephalitis induced by chemoradiotherapy and steroids in an esophageal cancer patient: a case report.
Topics: Acyclovir; Aged; Chemoradiotherapy; Cisplatin; Dexamethasone; Encephalitis, Herpes Simplex; Esophageal Neoplasms; Female; Fluorouracil; Herpesvirus 1, Human; Humans; Magnetic Resonance Imaging; Steroids | 2016 |
Acyclovir induces cell cycle perturbation and apoptosis in Jurkat leukemia cells, and enhances chemotherapeutic drug cytotoxicity.
Topics: Acyclovir; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Apoptosis; Cell Cycle; Cell Survival; Cisplatin; DNA Fragmentation; Dose-Response Relationship, Drug; Flow Cytometry; Fluorouracil; Humans; Jurkat Cells; K562 Cells; Leukemia; Time Factors; U937 Cells | 2018 |