Compounds > fluorouracil

fluorouracil and 3-methyladenine

fluorouracil has been researched along with 3-methyladenine in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (8.33)	29.6817
2010's	11 (91.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Faried, A; Hou, N; Kuwano, H; Li, J; Takeuchi, T; Tsutsumi, S	1
Bu, XX; Guo, XL; Hu, F; Li, R; Ma, NN; Song, JR; Sun, K; Tao, SF; Wei, LX; Wu, MC; Xiong, HY; Zhang, SS	1
Faried, A; Hou, N; Kuwano, H; Li, J; Tsutsumi, S	1
Deng, WJ; Guo, XL; Hu, F; Li, D; Song, JR; Song, YJ; Sun, K; Wei, LX; Wu, MC; Xie, XQ; Zhang, SS; Zhao, QD	1
Dong, DL; Guo, WT; Liu, X; Sheng, Y; Sun, B; Xing, Y; Zhang, YH	1
Cheng, PC; Chiang, WF; Hong, WZ; Lee, SY; Lin, MH; Lin, PY; Liu, SY; Liu, YC; Yen, CY	1
Chen, K; Duan, WM; Gong, FR; Gui, Q; Li, DM; Li, W; Lian, L; Liu, L; Shen, M; Tao, M; Wang, WJ; Wu, MY; Xu, MD; Zhu, J	1
Chen, L; Wang, J; Zhang, J; Zhang, L	1
Fang, JM; Guo, XL; Hu, F; Wang, H; Wei, LΧ; Xu, Q; Zhu, ZΖ	1
Chen, SH; Huang, KJ; Kuo, CH; Lee, YR; Lin, CY	1
Liu, T; Yang, JW; Zhang, QH	1
Ji, Z; Yang, S; Zhang, J; Zhang, L	1

Other Studies

12 other study(ies) available for fluorouracil and 3-methyladenine

Article	Year
Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells. Annals of surgical oncology, 2009, Volume: 16, Issue:3 Topics: Adenine; Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Blotting, Western; Caspase 3; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cytochromes c; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Humans	2009
Autophagic cell death induced by 5-FU in Bax or PUMA deficient human colon cancer cell. Cancer letters, 2010, Feb-01, Volume: 288, Issue:1 Topics: Adenine; Antimetabolites, Antineoplastic; Apoptosis Regulatory Proteins; Autophagy; bcl-2-Associated X Protein; Colonic Neoplasms; Dose-Response Relationship, Drug; Fluorouracil; HCT116 Cells; Humans; Intracellular Signaling Peptides and Proteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Signal Transduction; TOR Serine-Threonine Kinases	2010
Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model. European journal of cancer (Oxford, England : 1990), 2010, Volume: 46, Issue:10 Topics: Adenine; AMP-Activated Protein Kinase Kinases; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Autophagy-Related Protein 7; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Enzyme Inhibitors; Fluorouracil; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Protein Kinases; Random Allocation; RNA, Small Interfering; Transplantation, Heterologous; Tumor Suppressor Protein p53; Ubiquitin-Activating Enzymes	2010
Targeting autophagy potentiates chemotherapy-induced apoptosis and proliferation inhibition in hepatocarcinoma cells. Cancer letters, 2012, Jul-28, Volume: 320, Issue:2 Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cisplatin; Fluorouracil; Humans; Liver Neoplasms; Male; Membrane Potential, Mitochondrial; Membrane Proteins; Mice; Mice, Nude; Neoplasm Transplantation	2012
3-Methyladenine induces cell death and its interaction with chemotherapeutic drugs is independent of autophagy. Biochemical and biophysical research communications, 2013, Mar-01, Volume: 432, Issue:1 Topics: Adenine; Antineoplastic Agents; Autophagy; Cisplatin; Drug Agonism; Drug Synergism; Fluorouracil; HeLa Cells; Humans; MCF-7 Cells; Microtubule-Associated Proteins; Tamoxifen	2013
Long-term stimulation of areca nut components results in increased chemoresistance through elevated autophagic activity. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2014, Volume: 43, Issue:2 Topics: Actins; Adenine; Antimetabolites, Antineoplastic; Antineoplastic Agents; Areca; Autophagy; Autophagy-Related Proteins; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Chloroquine; Cisplatin; Cysteine Endopeptidases; Drug Resistance, Neoplasm; Fluorouracil; Glucose; Humans; Indicators and Reagents; Jurkat Cells; Microtubule-Associated Proteins; Mouth Neoplasms; Plant Extracts; Tetrazolium Salts; Time Factors	2014
Participation of autophagy in the cytotoxicity against breast cancer cells by cisplatin. Oncology reports, 2015, Volume: 34, Issue:1 Topics: Adenine; Antineoplastic Agents; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cisplatin; Cyclophosphamide; Docetaxel; Epirubicin; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Taxoids	2015
Autophagy in human skin squamous cell carcinoma: Inhibition by 3-MA enhances the effect of 5-FU-induced chemotherapy sensitivity. Oncology reports, 2015, Volume: 34, Issue:6 Topics: Adenine; Apoptosis; Autophagy; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Synergism; Fluorouracil; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Neoplasm Invasiveness; Proto-Oncogene Proteins c-bcl-2; Skin Neoplasms; Survivin	2015
Inhibition of autophagy in hepatocarcinoma cells promotes chemotherapeutic agent-induced apoptosis during nutrient deprivation. Oncology reports, 2018, Volume: 39, Issue:2 Topics: Adenine; Antineoplastic Agents; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Carcinoma, Hepatocellular; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Cisplatin; Fluorouracil; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; Mitochondria	2018
Honokiol inhibits in vitro and in vivo growth of oral squamous cell carcinoma through induction of apoptosis, cell cycle arrest and autophagy. Journal of cellular and molecular medicine, 2018, Volume: 22, Issue:3 Topics: Adenine; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Biphenyl Compounds; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Fluorouracil; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Lignans; Macrolides; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mouth Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Tumor Burden; Xenograft Model Antitumor Assays	2018
Autophagy facilitates anticancer effect of 5-fluorouracil in HCT-116 cells. Journal of cancer research and therapeutics, 2018, Volume: 14, Issue:Supplement Topics: Adenine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Beclin-1; Cell Proliferation; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; HCT116 Cells; Humans; Microtubule-Associated Proteins; RNA, Small Interfering; Sirolimus	2018
Photodynamic therapy enhances skin cancer chemotherapy effects through autophagy regulation. Photodiagnosis and photodynamic therapy, 2019, Volume: 28 Topics: Adenine; Aminolevulinic Acid; Autophagy; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Fluorouracil; Humans; Melanoma; Photochemotherapy; Photosensitizing Agents; Skin Neoplasms	2019