fluorouracil and 2-piperidone

fluorouracil has been researched along with 2-piperidone in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
James, LJ; Pardee, AB1
Alves, AP; Bezerra, DP; Costa-Lotufo, LV; de Alencar, NM; de Castro, FO; de Moraes, MO; Elmiro, FJ; Lima, MA; Lima, MW; Mesquita, RO; Pessoa, C; Silveira, ER1
Jadhav, RL; Magdum, CS; Patil, MV1
Chen, X; Li, W; Shang, SQ; Shen, HQ; Zhao, XL1
Akagi, Y; Matono, K; Ogata, Y; Shirouzu, K; Tsuda, H; Uchida, S; Ushijima, M1
Balzarini, J; Das, U; De Clercq, E; Dimmock, JR; Dimmock, SG; Iwamoto, S; Karki, SS; Kawase, M; Sakagami, H; Umemura, N1

Trials

1 trial(s) available for fluorouracil and 2-piperidone

ArticleYear
Randomized phase II study of 5-fluorouracil hepatic arterial infusion with or without antineoplastons as an adjuvant therapy after hepatectomy for liver metastases from colorectal cancer.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Combinations; Fluorouracil; Glutamine; Hepatectomy; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Middle Aged; Phenylacetates; Piperidones; Survival Analysis; Treatment Outcome

2015

Other Studies

5 other study(ies) available for fluorouracil and 2-piperidone

ArticleYear
Selective killing of transformed baby hamster kidney (BHK) cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1975, Volume: 72, Issue:12

    Topics: Antibiotics, Antineoplastic; Caffeine; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cyclohexanones; Cycloheximide; Fluorouracil; Piperidones; Polyomavirus; Puromycin; Urea

1975
In vitro and in vivo antitumor effect of 5-FU combined with piplartine and piperine.
    Journal of applied toxicology : JAT, 2008, Volume: 28, Issue:2

    Topics: Alanine Transaminase; Alkaloids; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Aspartate Aminotransferases; Benzodioxoles; Cell Proliferation; Dose-Response Relationship, Drug; Female; Fluorouracil; HL-60 Cells; Humans; Inhibitory Concentration 50; Kidney; Leukopenia; Liver; Mice; Piperidines; Piperidones; Polyunsaturated Alkamides; Sarcoma 180; Urea

2008
Synthesis and anticancer evaluation of furfurylidene 4-piperidone analogs.
    Archiv der Pharmazie, 2014, Volume: 347, Issue:6

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Survival; Doxorubicin; Drug Design; Fluorouracil; Humans; K562 Cells; Male; Mice; Molecular Structure; Piperidones; Structure-Activity Relationship; Time Factors; Tumor Burden

2014
Dual Inhibition of Cdc7 and Cdk9 by PHA-767491 Suppresses Hepatocarcinoma Synergistically with 5-Fluorouracil.
    Current cancer drug targets, 2015, Volume: 15, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Line, Tumor; Checkpoint Kinase 1; Cyclin-Dependent Kinase 9; Female; Fluorouracil; Humans; Liver Neoplasms; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; Myeloid Cell Leukemia Sequence 1 Protein; Phosphorylation; Piperidones; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Pyrroles; Xenograft Model Antitumor Assays

2015
3,5-Bis(3-alkylaminomethyl-4-hydroxybenzylidene)-4-piperidones: A Novel Class of Potent Tumor-Selective Cytotoxins.
    Journal of medicinal chemistry, 2016, Jan-28, Volume: 59, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Benzylidene Compounds; Cell Line, Tumor; Cell Proliferation; Cytotoxins; DNA Fragmentation; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Melphalan; Mice; Piperidones; Poly(ADP-ribose) Polymerases; Structure-Activity Relationship

2016