Compounds > fluorouracil

fluorouracil and 2'-deoxyuridylic acid

fluorouracil has been researched along with 2'-deoxyuridylic acid in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19906 (60.00)18.7374
1990's2 (20.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, TL; Erlichman, C1
Allegra, CJ; Chu, E; Lai, GM; Zinn, S1
Allegra, CJ; Fischer, PH; Grem, JL; Miller, EM; Mulcahy, RT1
Houghton, JA; Houghton, PJ; Torrance, PM; Weiss, KD; Williams, LG1
Berne, M; Bernstein, L; Frösing, R; Gustavsson, BG; Hayes, AA; Spears, CP1
Carlsson, G; Frösing, R; Gustavsson, BG; Spears, CP1
Chabner, BA; Donehower, RC; Liang, CM1
Heidelberger, C1
Carli, D; Cohen, S; Dumontet, C; Guitton, J; Honorat, M; Megherbi, M; Payen, L; Vignal, B1
Dong, Y; Guan, Z; Niu, B; Wang, J; Wang, X; Zhu, Z1

Other Studies

10 other study(ies) available for fluorouracil and 2'-deoxyuridylic acid

ArticleYear
Biochemical modulation of 5-fluorouracil with or without leucovorin by a low dose of brequinar in MGH-U1 cells.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Cell Survival; Cytidine Triphosphate; Deoxyuracil Nucleotides; Dose-Response Relationship, Drug; Drug Interactions; Fluorodeoxyuridylate; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; Leucovorin; Phosphoribosyl Pyrophosphate; Thymidylate Synthase; Tumor Cells, Cultured; Uridine Triphosphate

1992
Resistance of a human ovarian cancer line to 5-fluorouracil associated with decreased levels of 5-fluorouracil in DNA.
    Molecular pharmacology, 1990, Volume: 38, Issue:3

    Topics: Deoxyuracil Nucleotides; DNA Repair; DNA, Neoplasm; Drug Resistance; Female; Fluorouracil; Humans; Ovarian Neoplasms; RNA, Neoplasm; Thymidylate Synthase; Tumor Cells, Cultured

1990
Interaction of deoxyuridine with fluorouracil and dipyridamole in a human colon cancer cell line.
    Biochemical pharmacology, 1989, Jan-01, Volume: 38, Issue:1

    Topics: Cell Survival; Colonic Neoplasms; Deoxyuracil Nucleotides; Deoxyuridine; Dipyridamole; DNA; DNA Damage; Drug Interactions; Fluorouracil; Humans; RNA; Tumor Cells, Cultured

1989
Relationship between 5-fluoro-2'-deoxyuridylate, 2'-deoxyuridylate, and thymidylate synthase activity subsequent to 5-fluorouracil administration, in xenografts of human colon adenocarcinomas.
    Biochemical pharmacology, 1986, Apr-15, Volume: 35, Issue:8

    Topics: Adenocarcinoma; Adenosine Monophosphate; Animals; Cell Line; Colonic Neoplasms; Deoxyuracil Nucleotides; Drug Resistance; Fluorodeoxyuridylate; Fluorouracil; Humans; Hydrogen-Ion Concentration; Mice; Neoplasm Transplantation; Phosphoric Monoester Hydrolases; Thymidylate Synthase; Transplantation, Heterologous

1986
Mechanisms of innate resistance to thymidylate synthase inhibition after 5-fluorouracil.
    Cancer research, 1988, Oct-15, Volume: 48, Issue:20

    Topics: Adenocarcinoma; Breast Neoplasms; Colonic Neoplasms; Deoxyuracil Nucleotides; Drug Resistance; Fluorodeoxyuridylate; Fluorouracil; Humans; Pancreatic Neoplasms; Stomach Neoplasms; Thymidylate Synthase

1988
Pharmacodynamics of 5-fluorouracil and leucovorin.
    Advances in experimental medicine and biology, 1988, Volume: 244

    Topics: Adenocarcinoma; Animals; Bone Marrow; Colonic Neoplasms; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Fluorouracil; Humans; Intestinal Mucosa; Leucovorin; Liver; Pancreatic Neoplasms; Rats; Rats, Inbred Strains; Rectal Neoplasms; Stomach Neoplasms; Thymidylate Synthase

1988
Biochemical interactions between N-(phosphonacetyl)-L-aspartate and 5-fluorouracil.
    Molecular pharmacology, 1982, Volume: 21, Issue:1

    Topics: Animals; Aspartic Acid; Cells, Cultured; Deoxyuracil Nucleotides; Drug Interactions; Fluorodeoxyuridylate; Fluorouracil; Kinetics; Lacticaseibacillus casei; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; Sarcoma 180; Thymidylate Synthase

1982
On the rational development of a new drug: the example of the fluorinated pyrimidines.
    Cancer treatment reports, 1981, Volume: 65 Suppl 3

    Topics: Animals; Antimetabolites, Antineoplastic; Biotransformation; Deoxyuracil Nucleotides; DNA, Neoplasm; Fluorodeoxyuridylate; Fluorouracil; Humans; RNA, Neoplasm; Thymidylate Synthase

1981
Simultaneous quantification of 5-FU, 5-FUrd, 5-FdUrd, 5-FdUMP, dUMP and TMP in cultured cell models by LC-MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Oct-01, Volume: 877, Issue:27

    Topics: Cell Line; Cell Line, Tumor; Chromatography, Liquid; Deoxyuracil Nucleotides; Drug Stability; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Thymidine Monophosphate

2009
Inhibition of thymidylate synthase affects neural tube development in mice.
    Reproductive toxicology (Elmsford, N.Y.), 2018, Volume: 76

    Topics: Animals; Apoptosis; Cell Proliferation; Deoxyuracil Nucleotides; Embryonic Development; Fluorouracil; Mice, Inbred C57BL; Neural Tube; Neural Tube Defects; Neuroepithelial Cells; Thymidine; Thymidylate Synthase

2018