fluorouracil has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Huang, C; Jia, YM; Li, J; Liu, XH; Song, BA; Wu, XQ | 1 |
| Bar, J; Lukaschuk, N; Oren, M; Seger, R; Wilder, S; Zalcenstein, A | 1 |
| Arvind, R; Kaneda, Y; Matsumura, K; Omura, K; Sakai, E; Shimamoto, H; Tsuchida, N; Zhang, S | 1 |
| Chae, HS; Kang, JH; Kim, JO; Lee, SK; Shin, JY | 1 |
| Chen, J; Hu, C; Huang, XF; Katsifis, A | 1 |
| Bae, S; Chen, X; Datta, PK; Singh, K; Washington, MK; Zhang, B | 1 |
| Cheung, AL; Guan, XY; Law, S; Li, B; Li, J; Qin, YR; Tsao, SW; Xu, WW; Zhang, LY | 1 |
| Chen, X; Dou, L; Leng, C; Luo, X; Wu, C; Zhang, B; Zhang, Z | 1 |
| Li, LQ; Lu, SD; Peng, NF; Peng, YC; Xie, ZB; You, XM; Zhong, JH | 1 |
| Chen, H; Deng, Y; Duan, G; Li, X; Liu, H; Ma, Z; Qiu, L; Xiao, L; Xu, X; Zhao, LE; Zhu, Z | 1 |
11 other study(ies) available for fluorouracil and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Novel coumarin-dihydropyrazole thio-ethanone derivatives: design, synthesis and anticancer activity.
Topics: Antineoplastic Agents; Cell Line, Tumor; Coumarins; Drug Design; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Pyrazoles; Sulfhydryl Compounds | 2014 |
The PI3K inhibitor LY294002 prevents p53 induction by DNA damage and attenuates chemotherapy-induced apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Cell Line, Tumor; Chromones; Cisplatin; DNA Damage; Doxorubicin; Female; Fluorouracil; Humans; Mice; Mice, Inbred C57BL; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Tumor Suppressor Protein p53 | 2005 |
Role of caspase 8 as a determinant in chemosensitivity of p53-mutated head and neck squamous cell carcinoma cell lines.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Squamous Cell; Caspase 8; Caspases; Cell Line, Tumor; Chromones; Cisplatin; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Head and Neck Neoplasms; Humans; Membrane Glycoproteins; Morpholines; Mutation; Phosphorylation; Proto-Oncogene Proteins c-akt; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53 | 2006 |
LY294002 may overcome 5-FU resistance via down-regulation of activated p-AKT in Epstein-Barr virus-positive gastric cancer cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Cell Transformation, Neoplastic; Chromones; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Epstein-Barr Virus Infections; Fluorouracil; Herpesvirus 4, Human; Humans; Mitochondria; Morpholines; NF-kappa B; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Stomach Neoplasms; Tumor Cells, Cultured; Viral Matrix Proteins | 2010 |
Insulin decreases therapeutic efficacy in colon cancer cell line HT29 via the activation of the PI3K/Akt pathway.
Topics: Antineoplastic Agents; Cell Survival; Chromones; Colonic Neoplasms; Cycloheximide; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Activation; Fluorouracil; HT29 Cells; Humans; Insulin; Morpholines; Obesity; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Signal Transduction; Time Factors | 2011 |
Loss of Smad4 in colorectal cancer induces resistance to 5-fluorouracil through activating Akt pathway.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis Regulatory Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chromones; Colorectal Neoplasms; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Fluorouracil; Humans; Inhibitor of Apoptosis Proteins; Mice; Mice, Inbred BALB C; Morpholines; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Repressor Proteins; Retinoblastoma Protein; Smad4 Protein; Survivin; Up-Regulation; Vascular Endothelial Growth Factor A; Wound Healing; Xenograft Model Antitumor Assays | 2014 |
Suppression of esophageal tumor growth and chemoresistance by directly targeting the PI3K/AKT pathway.
Topics: Androstadienes; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chromones; Drug Resistance, Neoplasm; Enzyme Inhibitors; Esophageal Neoplasms; Female; Fluorouracil; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Morpholines; Neoplasm Transplantation; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Wortmannin | 2014 |
Smad4 sensitizes colorectal cancer to 5-fluorouracil through cell cycle arrest by inhibiting the PI3K/Akt/CDC2/survivin cascade.
Topics: Animals; Apoptosis; CDC2 Protein Kinase; Cell Cycle Checkpoints; Cell Proliferation; Chromones; Colorectal Neoplasms; Cyclin-Dependent Kinases; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Smad4 Protein; Survivin; Xenograft Model Antitumor Assays | 2016 |
Combination of 5-fluorouracil and 2-morphilino-8-phenyl-4H-chromen-4-one may inhibit liver cancer stem cell activity.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromones; Fluorouracil; Humans; Immunohistochemistry; Liver Neoplasms; Mice; Mice, Nude; Morpholines; Neoplastic Stem Cells; Polymerase Chain Reaction; Xenograft Model Antitumor Assays | 2016 |
DJ-1 is involved in the multidrug resistance of SGC7901 gastric cancer cells through PTEN/PI3K/Akt/Nrf2 pathway.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Chromones; Cisplatin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Gene Knockdown Techniques; Humans; Kelch-Like ECH-Associated Protein 1; Morpholines; NF-E2-Related Factor 2; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Deglycase DJ-1; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; PTEN Phosphohydrolase; Signal Transduction; Stomach Neoplasms; Up-Regulation; Vincristine | 2020 |